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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Ikzf2

Z-value: 1.39

Motif logo

Transcription factors associated with Ikzf2

Gene Symbol Gene ID Gene Info
ENSMUSG00000025997.14 Ikzf2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ikzf2mm39_v1_chr1_-_69724939_697249870.634.1e-05Click!

Activity profile of Ikzf2 motif

Sorted Z-values of Ikzf2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Ikzf2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_103800553 5.63 ENSMUST00000111140.3
ENSMUST00000111139.3
LIM domain only 2
chr15_+_80456775 5.53 ENSMUST00000229980.2
GRB2-related adaptor protein 2
chr2_+_103800459 5.53 ENSMUST00000111143.8
ENSMUST00000138815.2
LIM domain only 2
chr16_+_32427789 5.38 ENSMUST00000120680.2
transferrin receptor
chr14_-_70864448 5.08 ENSMUST00000110984.4
dematin actin binding protein
chr14_-_70864666 4.62 ENSMUST00000022694.17
dematin actin binding protein
chr10_+_115653152 4.46 ENSMUST00000080630.11
ENSMUST00000179196.3
ENSMUST00000035563.15
tetraspanin 8
chr5_-_148329615 3.47 ENSMUST00000138257.8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr15_-_66703471 3.41 ENSMUST00000164163.8
src-like adaptor
chr5_+_110478558 3.37 ENSMUST00000112481.2
polymerase (DNA directed), epsilon
chr6_-_40562700 3.25 ENSMUST00000177178.2
ENSMUST00000129948.9
ENSMUST00000101491.11
C-type lectin domain family 5, member a
chr11_+_31822211 3.11 ENSMUST00000020543.13
ENSMUST00000109412.9
cytoplasmic polyadenylation element binding protein 4
chr11_-_96859484 3.07 ENSMUST00000107623.8
Sp2 transcription factor
chr16_-_75706161 3.06 ENSMUST00000114239.9
SAM domain, SH3 domain and nuclear localization signals, 1
chr11_+_31823096 3.02 ENSMUST00000155278.2
cytoplasmic polyadenylation element binding protein 4
chr15_+_79578141 2.93 ENSMUST00000230898.2
ENSMUST00000229046.2
GTP binding protein 1
chr17_+_73144531 2.84 ENSMUST00000233886.2
yippee like 5
chr8_-_81466126 2.69 ENSMUST00000043359.9
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr9_+_123902143 2.60 ENSMUST00000168841.3
ENSMUST00000055918.7
chemokine (C-C motif) receptor 2
chr10_+_129219952 2.58 ENSMUST00000214064.2
olfactory receptor 784
chr4_-_149783097 2.48 ENSMUST00000038859.14
ENSMUST00000105690.9
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chrX_+_70600481 2.48 ENSMUST00000123100.2
high mobility group box 3
chr6_+_72526236 2.46 ENSMUST00000114071.8
capping protein (actin filament), gelsolin-like
chr1_-_133537953 2.44 ENSMUST00000164574.2
ENSMUST00000166291.8
ENSMUST00000164096.2
ENSMUST00000166915.8
small nuclear ribonucleoprotein E
chr11_-_78074377 2.35 ENSMUST00000102483.5
ribosomal protein L23A
chr13_-_103901010 2.35 ENSMUST00000210489.2
splicing regulatory glutamine/lysine-rich protein 1
chr4_+_134195631 2.30 ENSMUST00000030636.11
ENSMUST00000127279.8
ENSMUST00000105867.8
stathmin 1
chr16_-_19801781 2.25 ENSMUST00000058839.10
kelch-like 6
chr3_+_60436163 2.17 ENSMUST00000194201.6
ENSMUST00000193517.6
muscleblind like splicing factor 1
chr10_+_58230203 2.07 ENSMUST00000105468.2
LIM and senescent cell antigen-like domains 1
chr10_+_7543260 2.01 ENSMUST00000040135.9
nucleoporin 43
chr10_+_58230183 1.97 ENSMUST00000020077.11
LIM and senescent cell antigen-like domains 1
chr3_+_60436570 1.97 ENSMUST00000192607.6
muscleblind like splicing factor 1
chr13_-_61084358 1.96 ENSMUST00000225859.2
ENSMUST00000225167.2
ENSMUST00000021880.10
predicted gene, 49391
cytotoxic T lymphocyte-associated protein 2 alpha
chr19_-_53932581 1.95 ENSMUST00000236885.2
ENSMUST00000236098.2
ENSMUST00000236370.2
BBSome interacting protein 1
chr4_-_149783009 1.94 ENSMUST00000134534.8
ENSMUST00000146612.8
ENSMUST00000105688.10
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr1_-_160079007 1.85 ENSMUST00000191909.6
RAB GTPase activating protein 1-like
chr2_-_25498459 1.84 ENSMUST00000058137.9
RAB, member RAS oncogene family-like 6
chr2_-_26299173 1.82 ENSMUST00000145701.8
inositol polyphosphate-5-phosphatase E
chrX_+_162923474 1.73 ENSMUST00000073973.11
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr13_-_76205115 1.71 ENSMUST00000056130.8
G protein-coupled receptor 150
chrX_+_133501928 1.69 ENSMUST00000074950.11
ENSMUST00000113203.2
ENSMUST00000113202.8
ENSMUST00000050331.13
ENSMUST00000059297.6
heterogeneous nuclear ribonucleoprotein H2
chr16_-_90524214 1.67 ENSMUST00000099554.5
MIS18 kinetochore protein A
chr5_+_108213608 1.65 ENSMUST00000081567.11
ENSMUST00000170319.8
ENSMUST00000112626.8
metal response element binding transcription factor 2
chr13_+_23759930 1.64 ENSMUST00000105105.4
H3 clustered histone 4
chr7_+_46496929 1.61 ENSMUST00000132157.2
ENSMUST00000210631.2
lactate dehydrogenase A
chr4_-_92079986 1.57 ENSMUST00000123179.2
predicted gene 12666
chr6_+_72526414 1.53 ENSMUST00000155705.8
capping protein (actin filament), gelsolin-like
chr19_-_53932867 1.46 ENSMUST00000235688.2
ENSMUST00000235348.2
BBSome interacting protein 1
chr2_-_72810754 1.46 ENSMUST00000066003.7
trans-acting transcription factor 3
chr1_-_84818223 1.43 ENSMUST00000186465.7
thyroid hormone receptor interactor 12
chr6_+_4003904 1.42 ENSMUST00000031670.10
guanine nucleotide binding protein (G protein), gamma 11
chr4_-_44168252 1.40 ENSMUST00000145760.8
ENSMUST00000128426.8
ring finger protein 38
chrX_+_156481906 1.38 ENSMUST00000136141.2
ENSMUST00000190091.7
small muscle protein, X-linked
chr8_+_79755194 1.35 ENSMUST00000119254.8
ENSMUST00000238669.2
zinc finger protein 827
chr2_-_72810782 1.35 ENSMUST00000102689.10
trans-acting transcription factor 3
chr7_+_46496506 1.34 ENSMUST00000209984.2
lactate dehydrogenase A
chr2_-_26299112 1.30 ENSMUST00000114090.8
inositol polyphosphate-5-phosphatase E
chr5_+_31070739 1.29 ENSMUST00000031055.8
elastin microfibril interfacer 1
chr12_-_111947487 1.21 ENSMUST00000190536.2
retinal degeneration 3-like
chr8_+_121215155 1.21 ENSMUST00000034279.16
genetic suppressor element 1, coiled-coil protein
chr10_-_68377672 1.21 ENSMUST00000020103.9
ciliary associated calcium binding coiled-coil 1
chr17_-_56878438 1.19 ENSMUST00000131056.2
scaffold attachment factor B2
chr12_-_111947536 1.18 ENSMUST00000185354.2
retinal degeneration 3-like
chrX_+_156482116 1.18 ENSMUST00000112521.8
small muscle protein, X-linked
chrX_+_41241049 1.16 ENSMUST00000128799.3
stromal antigen 2
chr12_-_83486669 1.16 ENSMUST00000177801.2
D4, zinc and double PHD fingers, family 3
chr9_-_41068771 1.15 ENSMUST00000136530.8
ubiquitin associated and SH3 domain containing, B
chr7_+_46496552 1.14 ENSMUST00000005051.6
lactate dehydrogenase A
chr4_-_121072264 1.12 ENSMUST00000056635.13
rearranged L-myc fusion sequence
chr1_-_118239146 1.12 ENSMUST00000027623.9
translin
chr2_+_174171799 1.11 ENSMUST00000109085.8
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr13_+_23922783 1.09 ENSMUST00000040914.3
H1.2 linker histone, cluster member
chr3_+_89043440 1.07 ENSMUST00000047111.13
pyruvate kinase liver and red blood cell
chrX_+_111003193 1.03 ENSMUST00000130247.9
ENSMUST00000038546.7
testis expressed gene 16
chr6_-_35110560 1.03 ENSMUST00000202143.4
ENSMUST00000114993.9
ENSMUST00000114989.9
ENSMUST00000044163.10
ENSMUST00000202417.2
CCR4-NOT transcription complex, subunit 4
chr12_-_113823290 1.03 ENSMUST00000103459.5
immunoglobulin heavy variable 5-17
chr3_-_95902949 1.02 ENSMUST00000123006.8
ENSMUST00000130043.8
pleckstrin homology domain containing, family O member 1
chr18_+_69652837 1.01 ENSMUST00000201410.4
ENSMUST00000202937.4
transcription factor 4
chr3_-_69767208 0.97 ENSMUST00000171529.4
ENSMUST00000051239.13
serine palmitoyltransferase, small subunit B
chr17_+_24026892 0.92 ENSMUST00000191385.3
serine/arginine repetitive matrix 2
chr10_-_18890281 0.91 ENSMUST00000146388.2
tumor necrosis factor, alpha-induced protein 3
chr2_+_112097087 0.91 ENSMUST00000110987.9
ENSMUST00000028549.14
solute carrier family 12, member 6
chr13_-_54737857 0.90 ENSMUST00000148222.2
ENSMUST00000026987.12
NOP16 nucleolar protein
chr3_-_95903313 0.90 ENSMUST00000015889.10
pleckstrin homology domain containing, family O member 1
chr18_+_69652550 0.88 ENSMUST00000201205.4
transcription factor 4
chr13_+_83652352 0.88 ENSMUST00000198916.5
ENSMUST00000200123.5
ENSMUST00000005722.14
ENSMUST00000163888.8
myocyte enhancer factor 2C
chr9_+_123901979 0.85 ENSMUST00000171719.8
chemokine (C-C motif) receptor 2
chr5_-_116162415 0.82 ENSMUST00000031486.14
ENSMUST00000111999.8
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr18_+_69652751 0.82 ENSMUST00000200966.4
transcription factor 4
chr15_-_77037756 0.82 ENSMUST00000227314.2
ENSMUST00000227930.2
ENSMUST00000227533.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr19_-_53933052 0.81 ENSMUST00000135402.4
BBSome interacting protein 1
chr15_-_77037972 0.78 ENSMUST00000111581.4
ENSMUST00000166610.8
RNA binding protein, fox-1 homolog (C. elegans) 2
chr15_-_83033508 0.78 ENSMUST00000100375.11
polymerase (DNA-directed), delta interacting protein 3
chr7_-_133833734 0.77 ENSMUST00000134504.8
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr1_-_39517761 0.73 ENSMUST00000193823.2
ENSMUST00000054462.11
TBC1 domain family, member 8
chr19_-_29721012 0.71 ENSMUST00000175764.9
RIKEN cDNA 9930021J03 gene
chr3_-_95903145 0.71 ENSMUST00000143485.2
pleckstrin homology domain containing, family O member 1
chr12_-_113700190 0.71 ENSMUST00000103452.3
ENSMUST00000192264.2
immunoglobulin heavy variable 5-9-1
chr6_+_92793440 0.70 ENSMUST00000057977.4
RIKEN cDNA A730049H05 gene
chr5_-_103359117 0.69 ENSMUST00000112846.8
ENSMUST00000170792.9
ENSMUST00000112847.9
ENSMUST00000238446.3
ENSMUST00000133069.8
mitogen-activated protein kinase 10
chr15_-_83033559 0.69 ENSMUST00000058793.14
polymerase (DNA-directed), delta interacting protein 3
chr2_-_31006302 0.68 ENSMUST00000149196.2
formin binding protein 1
chr18_+_69652880 0.68 ENSMUST00000200813.4
transcription factor 4
chr12_-_113666198 0.67 ENSMUST00000103450.4
immunoglobulin heavy variable 5-12
chr3_+_159545309 0.67 ENSMUST00000068952.10
ENSMUST00000198878.2
wntless WNT ligand secretion mediator
chrX_+_105964224 0.67 ENSMUST00000060576.8
lysophosphatidic acid receptor 4
chr3_+_84832783 0.62 ENSMUST00000107675.8
F-box and WD-40 domain protein 7
chr1_-_69725045 0.61 ENSMUST00000190771.7
IKAROS family zinc finger 2
chr3_+_75982890 0.59 ENSMUST00000160261.8
follistatin-like 5
chr18_-_15284476 0.58 ENSMUST00000025992.7
potassium channel tetramerisation domain containing 1
chr19_-_59931432 0.57 ENSMUST00000170819.2
RAB11 family interacting protein 2 (class I)
chr6_-_128599833 0.57 ENSMUST00000171306.5
ENSMUST00000204819.3
ENSMUST00000032512.15
killer cell lectin-like receptor subfamily B member 1A
chr9_-_13245834 0.56 ENSMUST00000110582.4
Jrk-like
chr7_-_133833854 0.54 ENSMUST00000127524.2
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr17_-_75858835 0.52 ENSMUST00000234785.2
ENSMUST00000112507.4
family with sequence similarity 98, member A
chr1_-_69724939 0.51 ENSMUST00000027146.9
IKAROS family zinc finger 2
chr16_+_92089268 0.51 ENSMUST00000047383.10
potassium voltage-gated channel, Isk-related subfamily, gene 2
chr9_+_53448322 0.49 ENSMUST00000035850.8
nuclear protein in the AT region
chr18_-_36859732 0.49 ENSMUST00000061829.8
CD14 antigen
chr2_-_7400780 0.48 ENSMUST00000002176.13
CUGBP, Elav-like family member 2
chr13_+_49761506 0.44 ENSMUST00000021822.7
osteoglycin
chr2_+_118730823 0.44 ENSMUST00000151162.2
bromo adjacent homology domain containing 1
chrX_-_166907286 0.43 ENSMUST00000239138.2
FERM and PDZ domain containing 4
chr12_+_98737274 0.43 ENSMUST00000021399.9
zinc finger CCCH type containing 14
chr5_+_4073343 0.42 ENSMUST00000238634.2
A kinase (PRKA) anchor protein (yotiao) 9
chr10_-_44334683 0.41 ENSMUST00000105490.3
PR domain containing 1, with ZNF domain
chr19_+_55882942 0.39 ENSMUST00000142291.8
transcription factor 7 like 2, T cell specific, HMG box
chr5_-_88675700 0.38 ENSMUST00000087033.6
immunoglobulin joining chain
chr11_+_67090878 0.34 ENSMUST00000124516.8
ENSMUST00000018637.15
ENSMUST00000129018.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr17_+_6320731 0.32 ENSMUST00000088940.6
transmembrane protein 181A
chr3_-_61273228 0.31 ENSMUST00000066298.3
RIKEN cDNA B430305J03 gene
chr19_-_41065544 0.31 ENSMUST00000087176.8
oligodendrocytic myelin paranodal and inner loop protein
chr18_+_47245204 0.31 ENSMUST00000234633.2
heat shock protein 1 (chaperonin 10), related sequence 1
chr18_-_4352944 0.30 ENSMUST00000025078.10
mitogen-activated protein kinase kinase kinase 8
chrX_+_163156359 0.30 ENSMUST00000033751.8
vascular endothelial growth factor D
chr11_+_22970464 0.29 ENSMUST00000094363.4
ENSMUST00000151877.2
family with sequence similarity 161, member A
chr5_+_53747556 0.29 ENSMUST00000037618.13
ENSMUST00000201912.4
recombination signal binding protein for immunoglobulin kappa J region
chr10_-_89270554 0.29 ENSMUST00000220071.2
growth arrest-specific 2 like 3
chr1_-_156766381 0.29 ENSMUST00000188656.7
Ral GEF with PH domain and SH3 binding motif 2
chr10_-_44334711 0.28 ENSMUST00000039174.11
PR domain containing 1, with ZNF domain
chr17_+_17594808 0.27 ENSMUST00000232396.2
ENSMUST00000232199.2
RIO kinase 2
chr15_-_83033471 0.25 ENSMUST00000129372.2
polymerase (DNA-directed), delta interacting protein 3
chr6_-_128765529 0.25 ENSMUST00000167691.9
ENSMUST00000174404.8
killer cell lectin-like receptor subfamily B member 1C
chr5_+_20433169 0.24 ENSMUST00000197553.5
ENSMUST00000208219.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr10_+_107998033 0.23 ENSMUST00000219263.2
protein phosphatase 1, regulatory subunit 12A
chr5_-_51725059 0.23 ENSMUST00000127135.3
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr15_-_77037926 0.22 ENSMUST00000228087.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_-_87159237 0.22 ENSMUST00000113966.8
ENSMUST00000113964.2
interleukin 1 receptor accessory protein-like 1
chr3_+_32451820 0.22 ENSMUST00000108243.8
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr11_+_29413734 0.21 ENSMUST00000155854.8
coiled coil domain containing 88A
chr1_-_156766351 0.18 ENSMUST00000189648.2
Ral GEF with PH domain and SH3 binding motif 2
chr9_-_117081518 0.18 ENSMUST00000111773.10
ENSMUST00000068962.14
ENSMUST00000044901.14
RNA binding motif, single stranded interacting protein
chr12_+_76371679 0.18 ENSMUST00000172992.2
A kinase (PRKA) anchor protein 5
chr11_+_69909659 0.17 ENSMUST00000232002.2
ENSMUST00000134376.10
ENSMUST00000231221.2
discs large MAGUK scaffold protein 4
chr12_+_76371634 0.17 ENSMUST00000154078.3
ENSMUST00000095610.9
A kinase (PRKA) anchor protein 5
chr10_+_25235748 0.16 ENSMUST00000218903.2
erythrocyte membrane protein band 4.1 like 2
chr2_-_7400997 0.14 ENSMUST00000137733.9
CUGBP, Elav-like family member 2
chr13_+_83652150 0.14 ENSMUST00000198199.5
myocyte enhancer factor 2C
chr6_-_121450547 0.13 ENSMUST00000046373.8
ENSMUST00000151397.3
IQ motif and Sec7 domain 3
chr2_-_140513320 0.13 ENSMUST00000056760.4
fibronectin leucine rich transmembrane protein 3
chr2_+_72128239 0.13 ENSMUST00000144111.2
mitogen-activated protein kinase kinase kinase 20
chrX_+_133088238 0.12 ENSMUST00000064476.5
ADP-ribosylation factor-like 13A
chr16_+_41353360 0.12 ENSMUST00000099761.10
limbic system-associated membrane protein
chr6_-_57938488 0.10 ENSMUST00000228097.2
vomeronasal 1 receptor 24
chr13_+_83652280 0.10 ENSMUST00000199450.5
myocyte enhancer factor 2C
chr5_-_3707166 0.09 ENSMUST00000196304.2
GATA zinc finger domain containing 1
chr5_+_108213562 0.07 ENSMUST00000172045.8
metal response element binding transcription factor 2
chr7_+_91321500 0.07 ENSMUST00000238619.2
ENSMUST00000238467.2
discs large MAGUK scaffold protein 2
chr13_-_57043550 0.06 ENSMUST00000022023.13
ENSMUST00000174457.9
ENSMUST00000109871.8
transient receptor potential cation channel, subfamily C, member 7
chr2_-_140513382 0.06 ENSMUST00000110057.3
fibronectin leucine rich transmembrane protein 3
chr16_-_26810402 0.05 ENSMUST00000231299.2
geminin coiled-coil domain containing
chr6_-_119173699 0.04 ENSMUST00000239204.2
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr14_-_72840373 0.04 ENSMUST00000162825.8
fibronectin type III domain containing 3A
chr16_-_88571089 0.04 ENSMUST00000054223.4
RIKEN cDNA 2310057N15 gene
chr2_+_57887896 0.02 ENSMUST00000112616.8
ENSMUST00000166729.2
polypeptide N-acetylgalactosaminyltransferase 5
chrX_-_4194587 0.01 ENSMUST00000179325.2
BTB domain containing 35, family member 20
chr3_-_37180093 0.01 ENSMUST00000029275.6
interleukin 2
chr11_-_55310724 0.01 ENSMUST00000108858.8
ENSMUST00000141530.2
secreted acidic cysteine rich glycoprotein
chr1_+_45350698 0.00 ENSMUST00000087883.13
collagen, type III, alpha 1
chrX_+_102465616 0.00 ENSMUST00000182089.2
predicted gene, 26992

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.7 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
1.2 3.5 GO:2000451 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
1.1 3.4 GO:0045004 DNA replication proofreading(GO:0045004)
0.7 2.7 GO:0016584 nucleosome positioning(GO:0016584)
0.7 11.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.6 6.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.5 4.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.4 1.7 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.4 2.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.4 4.1 GO:0019659 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.4 4.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 1.7 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.3 5.4 GO:0033572 transferrin transport(GO:0033572)
0.3 2.3 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 0.9 GO:0034147 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.3 1.7 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.3 2.8 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.2 4.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.2 1.4 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.2 0.7 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.2 0.9 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 0.7 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 3.5 GO:0015809 arginine transport(GO:0015809)
0.2 1.8 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 1.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 3.1 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 2.6 GO:0051451 myoblast migration(GO:0051451)
0.1 0.5 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.1 3.4 GO:0042118 endothelial cell activation(GO:0042118)
0.1 1.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.5 GO:0071725 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 1.0 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 3.3 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.1 1.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 4.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 1.1 GO:0015074 DNA integration(GO:0015074)
0.1 0.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 3.1 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 4.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.1 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 5.6 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 3.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 2.3 GO:0002467 germinal center formation(GO:0002467)
0.1 2.0 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.8 GO:0035878 nail development(GO:0035878)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 1.7 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 2.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.3 GO:0036394 amylase secretion(GO:0036394)
0.1 2.9 GO:0046039 GTP metabolic process(GO:0046039)
0.0 1.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.5 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 2.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0009405 pathogenesis(GO:0009405)
0.0 0.4 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 1.6 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.3 GO:2000197 regulation of ribonucleoprotein complex localization(GO:2000197)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 1.3 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 2.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.7 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 2.0 GO:0051028 mRNA transport(GO:0051028)
0.0 2.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.2 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 1.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 3.1 GO:0035264 multicellular organism growth(GO:0035264)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 9.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.7 3.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.4 5.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.4 2.6 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3 1.0 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.3 4.2 GO:0034464 BBSome(GO:0034464)
0.3 2.6 GO:0005927 muscle tendon junction(GO:0005927)
0.3 3.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.2 6.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 4.0 GO:0090543 Flemming body(GO:0090543)
0.2 2.4 GO:0005687 U4 snRNP(GO:0005687)
0.2 2.9 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 4.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 0.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 2.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 2.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 4.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.0 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.7 GO:0000346 transcription export complex(GO:0000346)
0.1 0.4 GO:0044307 dendritic branch(GO:0044307)
0.1 0.2 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.1 0.5 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 4.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 2.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.9 GO:0071565 nBAF complex(GO:0071565)
0.0 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.3 GO:0008305 integrin complex(GO:0008305)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 2.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 2.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 2.2 GO:0005930 axoneme(GO:0005930)
0.0 10.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.0 GO:0002095 caveolar macromolecular signaling complex(GO:0002095)
0.0 1.4 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 5.3 GO:0016607 nuclear speck(GO:0016607)
0.0 2.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
1.1 5.4 GO:0004998 transferrin receptor activity(GO:0004998)
1.0 3.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.4 1.3 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.4 3.5 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.4 4.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 4.6 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.3 3.4 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 2.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.3 6.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.3 4.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.3 1.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 0.9 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.2 1.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 3.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 1.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 2.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.2 11.2 GO:0070888 E-box binding(GO:0070888)
0.1 0.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 3.3 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 9.9 GO:0030507 spectrin binding(GO:0030507)
0.1 0.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0019862 IgA binding(GO:0019862)
0.1 0.5 GO:0071723 lipopeptide binding(GO:0071723)
0.1 1.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.5 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 3.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.8 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 2.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 1.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.3 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 1.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 2.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 2.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 2.4 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 4.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 9.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 4.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 3.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 3.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.6 PID CD40 PATHWAY CD40/CD40L signaling
0.0 2.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 3.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 4.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 2.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 3.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2 4.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.2 5.8 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.1 3.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 4.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 5.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 4.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 4.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.8 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 2.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 2.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 1.3 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions