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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Irf5_Irf6

Z-value: 0.85

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Transcription factors associated with Irf5_Irf6

Gene Symbol Gene ID Gene Info
Irf5
ENSMUSG00000029771.13 Irf5
Irf6
ENSMUSG00000026638.16 Irf6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Irf6mm39_v1_chr1_+_192835414_1928355160.546.2e-04Click!
Irf5mm39_v1_chr6_+_29531247_295312690.115.2e-01Click!

Activity profile of Irf5_Irf6 motif

Sorted Z-values of Irf5_Irf6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf5_Irf6

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_-_35081129 4.30 ENSMUST00000154526.8
Cfb
complement factor B
chr17_-_35081456 4.25 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
Cfb
complement factor B
chr1_+_130754413 3.65 ENSMUST00000027675.14
ENSMUST00000133792.8
Pigr
polymeric immunoglobulin receptor
chr5_+_21391282 1.88 ENSMUST00000036031.13
ENSMUST00000198937.2
Gsap
gamma-secretase activating protein
chr17_+_31652073 1.84 ENSMUST00000237363.2
Pde9a
phosphodiesterase 9A
chr17_+_31652029 1.78 ENSMUST00000136384.9
Pde9a
phosphodiesterase 9A
chr3_-_142101418 1.73 ENSMUST00000029941.16
ENSMUST00000058626.9
Pdlim5
PDZ and LIM domain 5
chr9_+_44953723 1.48 ENSMUST00000034600.5
Mpzl2
myelin protein zero-like 2
chr17_+_35780977 1.46 ENSMUST00000174525.8
ENSMUST00000068291.7
H2-Q10
histocompatibility 2, Q region locus 10
chr4_-_46536088 1.39 ENSMUST00000102924.3
ENSMUST00000046897.13
Trim14
tripartite motif-containing 14
chr6_-_39095144 1.36 ENSMUST00000038398.7
Parp12
poly (ADP-ribose) polymerase family, member 12
chr14_-_73622638 1.26 ENSMUST00000228637.2
ENSMUST00000022704.9
Itm2b
integral membrane protein 2B
chr4_-_40239778 1.25 ENSMUST00000037907.13
Ddx58
DEAD/H box helicase 58
chr16_-_35691914 1.24 ENSMUST00000042665.9
Parp14
poly (ADP-ribose) polymerase family, member 14
chr9_-_123680927 1.24 ENSMUST00000184082.3
ENSMUST00000167595.9
Fyco1
FYVE and coiled-coil domain containing 1
chr1_+_52158693 1.21 ENSMUST00000189347.7
Stat1
signal transducer and activator of transcription 1
chr6_+_113448388 1.12 ENSMUST00000058300.14
Il17rc
interleukin 17 receptor C
chr1_+_52158599 1.11 ENSMUST00000186574.7
ENSMUST00000070968.14
ENSMUST00000191435.7
ENSMUST00000186857.7
ENSMUST00000188681.7
Stat1
signal transducer and activator of transcription 1
chr1_+_52158721 1.07 ENSMUST00000186057.7
Stat1
signal transducer and activator of transcription 1
chrM_+_9459 1.06 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr9_-_123680726 1.05 ENSMUST00000084715.14
Fyco1
FYVE and coiled-coil domain containing 1
chr14_-_78970160 1.05 ENSMUST00000226342.3
Dgkh
diacylglycerol kinase, eta
chr9_+_55234197 0.97 ENSMUST00000085754.10
ENSMUST00000034862.5
Tmem266
transmembrane protein 266
chr6_-_13607963 0.96 ENSMUST00000031554.9
ENSMUST00000149123.3
Tmem168
transmembrane protein 168
chr1_+_175459559 0.91 ENSMUST00000040250.15
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_+_175459735 0.89 ENSMUST00000097458.4
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr17_-_34506744 0.89 ENSMUST00000174751.2
ENSMUST00000040655.14
H2-Aa
histocompatibility 2, class II antigen A, alpha
chr3_-_142101339 0.87 ENSMUST00000198381.5
ENSMUST00000090134.12
ENSMUST00000196908.5
Pdlim5
PDZ and LIM domain 5
chr7_+_128125339 0.84 ENSMUST00000033136.9
Bag3
BCL2-associated athanogene 3
chr13_-_100689212 0.82 ENSMUST00000022140.12
Ocln
occludin
chr7_-_140846328 0.78 ENSMUST00000106023.8
ENSMUST00000097952.9
ENSMUST00000026571.11
Irf7
interferon regulatory factor 7
chr6_-_84564623 0.75 ENSMUST00000205228.3
Cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
chr13_-_100688949 0.73 ENSMUST00000159515.2
ENSMUST00000160859.8
ENSMUST00000069756.11
Ocln
occludin
chr16_+_23428650 0.72 ENSMUST00000038423.6
ENSMUST00000211349.2
Rtp4
receptor transporter protein 4
chr7_-_65020655 0.69 ENSMUST00000032729.8
Tjp1
tight junction protein 1
chr10_+_80085275 0.68 ENSMUST00000020361.7
Ndufs7
NADH:ubiquinone oxidoreductase core subunit S7
chr11_-_78875657 0.67 ENSMUST00000073001.5
Lgals9
lectin, galactose binding, soluble 9
chr16_+_35758836 0.61 ENSMUST00000114878.8
Parp9
poly (ADP-ribose) polymerase family, member 9
chr11_-_78875689 0.58 ENSMUST00000108269.10
ENSMUST00000108268.10
Lgals9
lectin, galactose binding, soluble 9
chr13_-_100689105 0.58 ENSMUST00000159459.8
Ocln
occludin
chr12_-_32000209 0.55 ENSMUST00000176084.2
ENSMUST00000176103.8
ENSMUST00000167458.9
Hbp1
high mobility group box transcription factor 1
chr5_-_91550853 0.55 ENSMUST00000121044.6
Btc
betacellulin, epidermal growth factor family member
chr2_-_6327884 0.55 ENSMUST00000238876.2
1700014B07Rik
RIKEN cDNA 1700014B07 gene
chr11_+_72192455 0.52 ENSMUST00000151440.8
ENSMUST00000146233.8
ENSMUST00000140842.9
Xaf1
XIAP associated factor 1
chr6_-_124888643 0.52 ENSMUST00000032217.2
Lag3
lymphocyte-activation gene 3
chr2_-_69416365 0.51 ENSMUST00000100051.9
ENSMUST00000092551.5
ENSMUST00000080953.12
Lrp2
low density lipoprotein receptor-related protein 2
chr2_-_77000878 0.49 ENSMUST00000111833.3
Ccdc141
coiled-coil domain containing 141
chr12_-_32000169 0.48 ENSMUST00000176520.8
Hbp1
high mobility group box transcription factor 1
chr6_-_38331187 0.46 ENSMUST00000114900.8
ENSMUST00000143702.5
Zc3hav1
zinc finger CCCH type, antiviral 1
chr4_-_40239700 0.45 ENSMUST00000142055.2
Ddx58
DEAD/H box helicase 58
chr1_-_105284383 0.45 ENSMUST00000058688.7
Rnf152
ring finger protein 152
chr16_-_67417687 0.44 ENSMUST00000120594.8
Cadm2
cell adhesion molecule 2
chr16_-_35759461 0.42 ENSMUST00000081933.14
ENSMUST00000114885.3
Dtx3l
deltex 3-like, E3 ubiquitin ligase
chrM_+_8603 0.42 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr4_-_116508842 0.36 ENSMUST00000030455.15
Akr1a1
aldo-keto reductase family 1, member A1 (aldehyde reductase)
chr1_+_182236728 0.35 ENSMUST00000117245.2
Trp53bp2
transformation related protein 53 binding protein 2
chr16_-_67417768 0.35 ENSMUST00000114292.8
ENSMUST00000120898.8
Cadm2
cell adhesion molecule 2
chr2_-_166904902 0.32 ENSMUST00000048988.14
Znfx1
zinc finger, NFX1-type containing 1
chr1_-_105284407 0.30 ENSMUST00000172299.2
Rnf152
ring finger protein 152
chr2_-_77349909 0.30 ENSMUST00000111830.9
Zfp385b
zinc finger protein 385B
chr15_-_76127600 0.28 ENSMUST00000165738.8
ENSMUST00000075689.7
Parp10
poly (ADP-ribose) polymerase family, member 10
chr1_-_75293997 0.27 ENSMUST00000189282.3
ENSMUST00000191254.7
Dnpep
aspartyl aminopeptidase
chr7_+_130294403 0.23 ENSMUST00000207282.2
Tacc2
transforming, acidic coiled-coil containing protein 2
chr9_+_95836839 0.22 ENSMUST00000189106.2
Xrn1
5'-3' exoribonuclease 1
chr12_-_73160181 0.22 ENSMUST00000043208.8
ENSMUST00000175693.3
Six4
sine oculis-related homeobox 4
chr8_-_36293588 0.21 ENSMUST00000060128.7
Cldn23
claudin 23
chr3_+_142202642 0.20 ENSMUST00000090127.7
Gbp5
guanylate binding protein 5
chrX_+_20714782 0.20 ENSMUST00000001155.11
ENSMUST00000122312.8
ENSMUST00000120356.8
ENSMUST00000122850.2
Araf
Araf proto-oncogene, serine/threonine kinase
chr13_-_30170031 0.19 ENSMUST00000102948.11
E2f3
E2F transcription factor 3
chr9_+_95836869 0.19 ENSMUST00000190665.2
Xrn1
5'-3' exoribonuclease 1
chr1_-_163141278 0.19 ENSMUST00000027878.14
Prrx1
paired related homeobox 1
chr9_+_117869642 0.19 ENSMUST00000134433.8
Azi2
5-azacytidine induced gene 2
chr19_-_7272758 0.18 ENSMUST00000025921.15
Mark2
MAP/microtubule affinity regulating kinase 2
chr9_+_117869577 0.18 ENSMUST00000133580.8
Azi2
5-azacytidine induced gene 2
chr6_-_70313491 0.17 ENSMUST00000103388.4
Igkv6-20
immunoglobulin kappa variable 6-20
chr17_-_32408431 0.17 ENSMUST00000087721.10
ENSMUST00000162117.3
Ephx3
epoxide hydrolase 3
chr2_-_77000936 0.17 ENSMUST00000164114.9
ENSMUST00000049544.14
Ccdc141
coiled-coil domain containing 141
chr19_+_44744484 0.16 ENSMUST00000174490.9
Pax2
paired box 2
chr1_-_163141230 0.16 ENSMUST00000174397.3
ENSMUST00000075805.13
Prrx1
paired related homeobox 1
chr9_+_117869543 0.15 ENSMUST00000044454.12
Azi2
5-azacytidine induced gene 2
chr1_-_75293942 0.15 ENSMUST00000187075.7
Dnpep
aspartyl aminopeptidase
chr12_+_119354110 0.14 ENSMUST00000222058.2
Macc1
metastasis associated in colon cancer 1
chr5_+_92957231 0.13 ENSMUST00000113054.9
Shroom3
shroom family member 3
chr11_+_29080733 0.13 ENSMUST00000020756.9
Pnpt1
polyribonucleotide nucleotidyltransferase 1
chr10_-_114638202 0.13 ENSMUST00000239411.2
Trhde
TRH-degrading enzyme
chr13_-_59970383 0.11 ENSMUST00000225987.2
Tut7
terminal uridylyl transferase 7
chr17_+_34863738 0.09 ENSMUST00000036720.9
Fkbpl
FK506 binding protein-like
chr6_+_70663930 0.09 ENSMUST00000103402.2
Igkv3-3
immunoglobulin kappa variable 3-3
chr17_+_34863779 0.09 ENSMUST00000174796.2
Fkbpl
FK506 binding protein-like
chr12_-_32000534 0.07 ENSMUST00000172314.9
Hbp1
high mobility group box transcription factor 1
chr8_+_62381115 0.07 ENSMUST00000154398.8
ENSMUST00000156980.8
ENSMUST00000093485.3
ENSMUST00000070631.15
Ddx60
DExD/H box helicase 60
chr19_-_5610628 0.04 ENSMUST00000025861.3
Ovol1
ovo like zinc finger 1
chr9_-_123691077 0.04 ENSMUST00000182350.3
Xcr1
chemokine (C motif) receptor 1
chr3_+_135144481 0.02 ENSMUST00000199582.5
Ube2d3
ubiquitin-conjugating enzyme E2D 3
chr2_-_44912927 0.00 ENSMUST00000202432.4
Zeb2
zinc finger E-box binding homeobox 2
chr9_+_56979307 0.00 ENSMUST00000169879.8
Sin3a
transcriptional regulator, SIN3A (yeast)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0002414 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.1 3.4 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
0.5 8.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 2.3 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.4 1.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.3 1.7 GO:0009597 detection of virus(GO:0009597)
0.3 1.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.3 1.3 GO:0043321 regulation of natural killer cell degranulation(GO:0043321)
0.2 3.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.8 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 0.8 GO:1902811 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 2.1 GO:0070673 response to interleukin-18(GO:0070673)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 1.9 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.2 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.1 0.4 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.1 1.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.2 GO:0021634 optic nerve formation(GO:0021634) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.1 1.1 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1 0.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 1.4 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 1.0 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.0 0.6 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.0 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.9 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.8 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 2.6 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.6 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.4 GO:0090503 histone mRNA catabolic process(GO:0071044) RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 1.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.3 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.5 GO:0045056 transcytosis(GO:0045056)
0.0 1.1 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.0 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.7 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.2 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 3.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 6.0 GO:0072562 blood microparticle(GO:0072562)
0.0 2.0 GO:0005776 autophagosome(GO:0005776)
0.0 3.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 3.6 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 2.0 GO:0043296 apical junction complex(GO:0043296)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.6 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.3 3.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 0.5 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 1.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 1.3 GO:0016936 galactoside binding(GO:0016936)
0.1 0.8 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 3.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 3.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.7 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 2.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 2.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.7 GO:0071253 connexin binding(GO:0071253)
0.1 1.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 3.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 8.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 1.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 8.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 3.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 3.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 3.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex