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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Lef1

Z-value: 0.84

Motif logo

Transcription factors associated with Lef1

Gene Symbol Gene ID Gene Info
ENSMUSG00000027985.15 Lef1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lef1mm39_v1_chr3_+_130904000_130904120-0.251.4e-01Click!

Activity profile of Lef1 motif

Sorted Z-values of Lef1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Lef1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_70305267 2.24 ENSMUST00000100043.3
trans-acting transcription factor 5
chrX_+_108138965 1.31 ENSMUST00000033598.9
SH3-binding domain glutamic acid-rich protein like
chr10_-_128796834 1.28 ENSMUST00000026398.5
methyltransferase like 7B
chr1_-_139708906 1.15 ENSMUST00000111986.8
ENSMUST00000027612.11
ENSMUST00000111989.9
complement factor H-related 4
chr11_+_108811626 1.10 ENSMUST00000140821.2
axin 2
chr15_-_58078274 0.95 ENSMUST00000022986.8
F-box protein 32
chr4_-_151946219 0.88 ENSMUST00000097774.9
calmodulin binding transcription activator 1
chr4_-_151946155 0.83 ENSMUST00000049790.14
calmodulin binding transcription activator 1
chr18_-_61169262 0.77 ENSMUST00000025521.9
caudal type homeobox 1
chr10_-_95159933 0.75 ENSMUST00000053594.7
CASP2 and RIPK1 domain containing adaptor with death domain
chr6_-_52217821 0.74 ENSMUST00000121043.2
homeobox A10
chr1_+_16175998 0.71 ENSMUST00000027053.8
retinol dehydrogenase 10 (all-trans)
chr2_-_154916367 0.70 ENSMUST00000137242.2
ENSMUST00000054607.16
S-adenosylhomocysteine hydrolase
chr8_+_45960804 0.69 ENSMUST00000067065.14
ENSMUST00000124544.8
ENSMUST00000138049.9
ENSMUST00000132139.9
sorbin and SH3 domain containing 2
chr6_+_17463748 0.69 ENSMUST00000115443.8
met proto-oncogene
chr10_+_85763545 0.67 ENSMUST00000170396.3
achaete-scute family bHLH transcription factor 4
chr4_-_151946124 0.66 ENSMUST00000169423.9
calmodulin binding transcription activator 1
chr5_-_147244074 0.66 ENSMUST00000031650.4
caudal type homeobox 2
chr4_-_114844417 0.63 ENSMUST00000030491.9
cytidine monophosphate (UMP-CMP) kinase 1
chr8_-_86159398 0.63 ENSMUST00000047749.7
RIKEN cDNA 4921524J17 gene
chr8_+_45960931 0.61 ENSMUST00000171337.10
ENSMUST00000067107.15
sorbin and SH3 domain containing 2
chr17_+_74645936 0.60 ENSMUST00000224711.2
ENSMUST00000024869.8
ENSMUST00000233611.2
spastin
chr3_-_57483330 0.59 ENSMUST00000120977.2
WW domain containing transcription regulator 1
chrX_-_37653396 0.58 ENSMUST00000016681.15
cullin 4B
chr3_-_57483175 0.58 ENSMUST00000029380.14
WW domain containing transcription regulator 1
chr9_+_54771064 0.58 ENSMUST00000034843.9
iron responsive element binding protein 2
chr9_+_22365586 0.58 ENSMUST00000168332.2
predicted gene, 17545
chr6_-_47790272 0.57 ENSMUST00000077290.9
protein disulfide isomerase associated 4
chr9_+_59524521 0.57 ENSMUST00000026267.16
ENSMUST00000050483.15
poly (ADP-ribose) polymerase family, member 6
chr11_-_120551494 0.57 ENSMUST00000106178.9
notum palmitoleoyl-protein carboxylesterase
chr11_+_108812474 0.56 ENSMUST00000144511.2
axin 2
chr19_+_55730696 0.54 ENSMUST00000153888.9
ENSMUST00000127233.9
ENSMUST00000061496.17
ENSMUST00000111656.8
ENSMUST00000111657.11
transcription factor 7 like 2, T cell specific, HMG box
chr6_-_124519240 0.54 ENSMUST00000159463.8
ENSMUST00000162844.2
ENSMUST00000160505.8
ENSMUST00000162443.8
complement component 1, s subcomponent 1
chr1_+_59555423 0.54 ENSMUST00000114243.8
predicted gene 973
chr16_+_19916292 0.53 ENSMUST00000023509.5
ENSMUST00000232088.2
ENSMUST00000231842.2
kelch-like 24
chr13_+_89687915 0.53 ENSMUST00000022108.9
hyaluronan and proteoglycan link protein 1
chr18_-_12995913 0.53 ENSMUST00000121774.8
oxysterol binding protein-like 1A
chr4_+_116414855 0.51 ENSMUST00000030460.15
GC-rich promoter binding protein 1-like 1
chr3_-_75864195 0.51 ENSMUST00000038563.14
ENSMUST00000167078.8
ENSMUST00000117242.8
golgi integral membrane protein 4
chr5_+_92285748 0.51 ENSMUST00000031355.10
ENSMUST00000202155.2
USO1 vesicle docking factor
chr10_+_29019645 0.51 ENSMUST00000092629.4
SOGA family member 3
chr17_-_34822649 0.50 ENSMUST00000015622.8
ring finger protein 5
chr11_+_87959067 0.50 ENSMUST00000018521.11
vascular endothelial zinc finger 1
chr9_+_74883377 0.49 ENSMUST00000081746.7
family with sequence similarity 214, member A
chr3_-_127631068 0.49 ENSMUST00000051737.8
ENSMUST00000200409.5
adaptor-related protein complex 1 associated regulatory protein
chr2_+_74505350 0.48 ENSMUST00000001878.6
homeobox D12
chr2_-_75534985 0.48 ENSMUST00000102672.5
nuclear factor, erythroid derived 2, like 2
chr4_+_98919183 0.48 ENSMUST00000030280.7
angiopoietin-like 3
chr9_-_96634874 0.48 ENSMUST00000152594.8
zinc finger and BTB domain containing 38
chr3_-_53771185 0.47 ENSMUST00000122330.2
ENSMUST00000146598.8
ubiquitin-fold modifier 1
chr14_+_49409659 0.47 ENSMUST00000153488.9
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr2_+_29968225 0.47 ENSMUST00000150770.8
protein kinase N3
chr18_+_36098090 0.46 ENSMUST00000176873.8
ENSMUST00000177432.8
ENSMUST00000175734.2
pleckstrin and Sec7 domain containing 2
chr8_-_85500010 0.46 ENSMUST00000109764.8
nuclear factor I/X
chr6_-_86710250 0.46 ENSMUST00000001185.14
germ cell-less, spermatogenesis associated 1
chr8_+_109441276 0.46 ENSMUST00000043896.10
zinc finger homeobox 3
chr9_+_119978773 0.45 ENSMUST00000068698.15
ENSMUST00000215512.2
ENSMUST00000111627.3
ENSMUST00000093773.8
myelin-associated oligodendrocytic basic protein
chr7_-_144493560 0.45 ENSMUST00000093962.5
cyclin D1
chr5_+_30437579 0.45 ENSMUST00000145167.9
selenoprotein I
chr1_+_42734051 0.44 ENSMUST00000239323.2
ENSMUST00000199521.5
ENSMUST00000176807.3
POU domain, class 3, transcription factor 3
predicted gene 20646
chr15_-_44291226 0.44 ENSMUST00000227843.2
NudC domain containing 1
chr11_+_96162283 0.44 ENSMUST00000000010.9
ENSMUST00000174042.3
homeobox B9
chr9_+_43996236 0.43 ENSMUST00000065461.9
ENSMUST00000176416.8
ubiquitin specific peptidase 2
chr19_-_43663282 0.43 ENSMUST00000046038.9
ENSMUST00000236433.2
solute carrier family 25, member 28
chr18_-_23171713 0.43 ENSMUST00000081423.13
nucleolar protein 4
chr15_-_50753792 0.43 ENSMUST00000185183.2
transcriptional repressor GATA binding 1
chr2_-_65068917 0.42 ENSMUST00000090896.10
ENSMUST00000155082.2
Cobl-like 1
chr1_+_180468895 0.42 ENSMUST00000192725.6
lin-9 homolog (C. elegans)
chr1_-_173195236 0.42 ENSMUST00000005470.5
ENSMUST00000111220.8
cell adhesion molecule 3
chr4_+_97665992 0.41 ENSMUST00000107062.9
ENSMUST00000052018.12
ENSMUST00000107057.8
nuclear factor I/A
chr19_-_30526916 0.41 ENSMUST00000025803.9
dickkopf WNT signaling pathway inhibitor 1
chr12_-_83643883 0.41 ENSMUST00000221919.2
zinc finger, FYVE domain containing 1
chr17_+_48717007 0.41 ENSMUST00000167180.8
ENSMUST00000046651.7
ENSMUST00000233426.2
O-acyl-ADP-ribose deacylase 1
chr2_-_65397850 0.40 ENSMUST00000238483.2
ENSMUST00000100069.9
sodium channel, voltage-gated, type III, alpha
chr1_-_189075903 0.40 ENSMUST00000192723.2
ENSMUST00000110920.7
potassium channel, subfamily K, member 2
chr9_+_62249177 0.40 ENSMUST00000128636.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr11_+_110289941 0.39 ENSMUST00000020949.12
ENSMUST00000100260.2
mitogen-activated protein kinase kinase 6
chr5_-_28415020 0.39 ENSMUST00000118882.2
canopy FGF signaling regulator 1
chr11_-_120552001 0.38 ENSMUST00000150458.2
notum palmitoleoyl-protein carboxylesterase
chr2_-_170248421 0.38 ENSMUST00000154650.8
breast carcinoma amplified sequence 1
chr5_-_28415166 0.38 ENSMUST00000117098.2
canopy FGF signaling regulator 1
chr12_-_83643964 0.38 ENSMUST00000048319.6
zinc finger, FYVE domain containing 1
chr1_+_158190090 0.38 ENSMUST00000194369.6
ENSMUST00000195311.6
astrotactin 1
chr4_+_41465134 0.38 ENSMUST00000030154.7
nudix (nucleoside diphosphate linked moiety X)-type motif 2
chr4_-_91264727 0.38 ENSMUST00000107124.10
ELAV like RNA binding protein 1
chr19_+_55730316 0.38 ENSMUST00000111658.10
transcription factor 7 like 2, T cell specific, HMG box
chr8_+_23114035 0.37 ENSMUST00000033936.8
dickkopf WNT signaling pathway inhibitor 4
chr6_-_148846247 0.37 ENSMUST00000111562.8
ENSMUST00000081956.12
SIN3-HDAC complex associated factor
chrX_+_152281200 0.37 ENSMUST00000060714.10
ubiquilin 2
chr12_-_119202527 0.37 ENSMUST00000026360.9
integrin beta 8
chr4_-_91264670 0.37 ENSMUST00000107109.9
ENSMUST00000107111.9
ENSMUST00000107120.8
ELAV like RNA binding protein 1
chr15_-_84739292 0.37 ENSMUST00000016768.12
PHD finger protein 21B
chr1_+_131671751 0.37 ENSMUST00000049027.10
solute carrier family 26, member 9
chr13_-_111626562 0.37 ENSMUST00000091236.11
ENSMUST00000047627.14
GC-rich promoter binding protein 1
chr4_+_8691303 0.37 ENSMUST00000051558.10
chromodomain helicase DNA binding protein 7
chr2_-_65068960 0.37 ENSMUST00000112429.9
ENSMUST00000102726.8
ENSMUST00000112430.8
Cobl-like 1
chr14_-_48900192 0.36 ENSMUST00000122009.8
orthodenticle homeobox 2
chr3_-_69034425 0.36 ENSMUST00000194558.6
ENSMUST00000029353.9
karyopherin (importin) alpha 4
chr13_-_72111832 0.36 ENSMUST00000077337.9
Iroquois homeobox 1
chr17_+_74835290 0.36 ENSMUST00000180037.8
baculoviral IAP repeat-containing 6
chr13_+_9326513 0.36 ENSMUST00000174552.8
disco interacting protein 2 homolog C
chrX_+_128650579 0.35 ENSMUST00000113320.3
diaphanous related formin 2
chr9_+_62248611 0.35 ENSMUST00000085519.13
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr7_-_49286594 0.35 ENSMUST00000032717.7
developing brain homeobox 1
chr4_+_99544536 0.35 ENSMUST00000087285.5
forkhead box D3
chr4_+_47208004 0.35 ENSMUST00000082303.13
ENSMUST00000102917.11
collagen, type XV, alpha 1
chr9_-_51076724 0.34 ENSMUST00000210433.2
predicted gene, 32742
chr2_-_6726701 0.34 ENSMUST00000114927.9
CUGBP, Elav-like family member 2
chr1_+_191638854 0.34 ENSMUST00000044954.7
solute carrier family 30 (zinc transporter), member 1
chr6_-_94260806 0.34 ENSMUST00000203519.3
ENSMUST00000204347.3
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr3_+_59939175 0.34 ENSMUST00000029325.5
arylacetamide deacetylase
chr12_-_57592907 0.33 ENSMUST00000044380.8
forkhead box A1
chr3_+_94391676 0.33 ENSMUST00000198384.3
CUGBP, Elav-like family member 3
chr2_-_65397809 0.33 ENSMUST00000066432.12
sodium channel, voltage-gated, type III, alpha
chr2_+_15060051 0.33 ENSMUST00000069870.11
ENSMUST00000239125.2
ENSMUST00000193836.3
ADP-ribosylation factor-like 5B
chr1_+_158189831 0.33 ENSMUST00000193042.6
ENSMUST00000046110.16
astrotactin 1
chr16_-_4377640 0.33 ENSMUST00000005862.9
transcription factor AP4
chr1_-_189075515 0.33 ENSMUST00000193319.6
potassium channel, subfamily K, member 2
chr17_+_52909721 0.33 ENSMUST00000039366.11
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr14_-_80008745 0.32 ENSMUST00000039568.11
ENSMUST00000195355.2
protocadherin 8
chr13_-_101831020 0.32 ENSMUST00000185795.2
phosphoinositide-3-kinase regulatory subunit 1
chr13_-_104246084 0.32 ENSMUST00000224945.2
ENSMUST00000109315.5
neurolysin (metallopeptidase M3 family)
chr2_-_6726998 0.32 ENSMUST00000182657.2
CUGBP, Elav-like family member 2
chr14_+_70791496 0.32 ENSMUST00000022691.14
lysine demethylase and nuclear receptor corepressor
chr5_+_65288418 0.32 ENSMUST00000101191.10
ENSMUST00000204348.3
kelch-like 5
chr8_+_105897542 0.32 ENSMUST00000109394.3
core binding factor beta
chr6_+_15184630 0.32 ENSMUST00000115470.3
forkhead box P2
chrX_+_128650486 0.31 ENSMUST00000167619.9
ENSMUST00000037854.15
diaphanous related formin 2
chr1_-_155617773 0.31 ENSMUST00000027740.14
LIM homeobox protein 4
chr14_-_100522101 0.31 ENSMUST00000228216.2
Kruppel-like factor 12
chr11_-_33793461 0.31 ENSMUST00000101368.9
ENSMUST00000065970.6
ENSMUST00000109340.9
Kv channel-interacting protein 1
chr8_+_70945806 0.31 ENSMUST00000008032.14
cytokine receptor-like factor 1
chr10_-_25412010 0.31 ENSMUST00000179685.3
small leucine-rich protein 1
chr3_-_30563611 0.31 ENSMUST00000173899.8
MDS1 and EVI1 complex locus
chr4_-_148711453 0.31 ENSMUST00000165113.8
ENSMUST00000172073.8
ENSMUST00000105702.9
ENSMUST00000084125.10
TAR DNA binding protein
chr4_+_136038301 0.30 ENSMUST00000084219.12
heterogeneous nuclear ribonucleoprotein R
chrX_+_102365004 0.30 ENSMUST00000033689.3
caudal type homeobox 4
chr2_-_25982160 0.30 ENSMUST00000114159.9
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chrX_-_16777913 0.30 ENSMUST00000040134.8
Norrie disease (pseudoglioma) (human)
chr2_+_146063841 0.30 ENSMUST00000089257.6
insulinoma-associated 1
chr3_+_94391644 0.30 ENSMUST00000197677.5
CUGBP, Elav-like family member 3
chr2_+_18677195 0.30 ENSMUST00000171845.8
ENSMUST00000061158.5
COMM domain containing 3
chr7_-_126496534 0.30 ENSMUST00000120007.8
transmembrane protein 219
chrX_+_142301666 0.30 ENSMUST00000134402.8
p21 (RAC1) activated kinase 3
chr3_-_116217579 0.30 ENSMUST00000106491.7
ENSMUST00000090464.7
CDC14 cell division cycle 14A
chr5_+_150119860 0.30 ENSMUST00000202600.4
FRY microtubule binding protein
chr1_+_158189900 0.30 ENSMUST00000170718.7
astrotactin 1
chr15_+_44291470 0.30 ENSMUST00000226827.2
ENSMUST00000060652.5
ENY2 transcription and export complex 2 subunit
chr1_+_55445033 0.30 ENSMUST00000042986.10
phospholipase C-like 1
chr4_-_82623972 0.29 ENSMUST00000155821.2
nuclear factor I/B
chr9_+_109961048 0.29 ENSMUST00000088716.12
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr2_+_55327110 0.29 ENSMUST00000112633.3
ENSMUST00000112632.2
potassium inwardly-rectifying channel, subfamily J, member 3
chr9_-_75317233 0.29 ENSMUST00000049355.11
mitogen-activated protein kinase 6
chr17_+_26633794 0.29 ENSMUST00000182897.8
ENSMUST00000183077.8
ENSMUST00000053020.8
neuralized E3 ubiquitin protein ligase 1B
chr8_+_85807369 0.29 ENSMUST00000079764.14
WD repeat domain 83 opposite strand
chr13_-_30168374 0.29 ENSMUST00000221536.2
ENSMUST00000222730.2
E2F transcription factor 3
chr11_-_99907030 0.29 ENSMUST00000018399.3
keratin 33A
chr11_-_86698484 0.29 ENSMUST00000018569.14
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr11_+_108811168 0.29 ENSMUST00000052915.14
axin 2
chr5_+_53748323 0.29 ENSMUST00000201883.4
recombination signal binding protein for immunoglobulin kappa J region
chr18_+_35731658 0.29 ENSMUST00000041314.17
ENSMUST00000236666.2
ENSMUST00000236020.2
ENSMUST00000235400.2
polyadenylate-binding protein-interacting protein 2
chr16_-_4950285 0.28 ENSMUST00000035672.5
periplakin
chr9_-_59393893 0.28 ENSMUST00000171975.8
ariadne RBR E3 ubiquitin protein ligase 1
chr7_+_27879650 0.28 ENSMUST00000172467.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr19_-_14575395 0.28 ENSMUST00000052011.15
ENSMUST00000167776.3
transducin-like enhancer of split 4
chr2_-_69416365 0.28 ENSMUST00000100051.9
ENSMUST00000092551.5
ENSMUST00000080953.12
low density lipoprotein receptor-related protein 2
chr11_+_120382666 0.28 ENSMUST00000026899.4
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr19_+_55730242 0.28 ENSMUST00000111662.11
ENSMUST00000041717.14
transcription factor 7 like 2, T cell specific, HMG box
chr5_+_17779721 0.28 ENSMUST00000169603.2
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr4_+_13751297 0.28 ENSMUST00000105566.9
RUNX1 translocation partner 1
chr19_+_8816663 0.28 ENSMUST00000160556.8
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr6_+_110622533 0.28 ENSMUST00000071076.13
ENSMUST00000172951.2
glutamate receptor, metabotropic 7
chr5_-_132570710 0.28 ENSMUST00000182974.9
autism susceptibility candidate 2
chr4_-_21685781 0.28 ENSMUST00000076206.11
PR domain containing 13
chr12_-_56660054 0.28 ENSMUST00000072631.6
NK2 homeobox 9
chr8_-_85526653 0.28 ENSMUST00000126806.2
ENSMUST00000076715.13
nuclear factor I/X
chr10_+_69761630 0.27 ENSMUST00000182029.8
ankyrin 3, epithelial
chr7_+_82516491 0.27 ENSMUST00000082237.7
mex3 RNA binding family member B
chr4_-_20778530 0.27 ENSMUST00000119374.8
Na+/K+ transporting ATPase interacting 3
chr8_+_40964818 0.27 ENSMUST00000098817.4
vacuolar protein sorting 37A
chr12_+_76417040 0.27 ENSMUST00000042779.4
zinc finger and BTB domain containing 1
chr6_+_134012602 0.27 ENSMUST00000081028.13
ENSMUST00000111963.8
ets variant 6
chr4_-_20778847 0.27 ENSMUST00000102998.4
Na+/K+ transporting ATPase interacting 3
chr4_+_116415251 0.27 ENSMUST00000106475.2
GC-rich promoter binding protein 1-like 1
chr9_+_61280890 0.27 ENSMUST00000161689.8
transducin-like enhancer of split 3
chr6_-_52195663 0.26 ENSMUST00000134367.4
homeobox A7
chr19_+_21249636 0.26 ENSMUST00000237651.2
zinc finger, AN1-type domain 5
chr19_-_58443012 0.26 ENSMUST00000129100.8
ENSMUST00000123957.2
glial cell line derived neurotrophic factor family receptor alpha 1
chrX_-_163041185 0.26 ENSMUST00000112265.9
BMX non-receptor tyrosine kinase
chr3_+_130904000 0.26 ENSMUST00000029611.14
ENSMUST00000106341.9
ENSMUST00000066849.13
lymphoid enhancer binding factor 1
chr19_-_34855242 0.26 ENSMUST00000238065.2
pantothenate kinase 1
chr18_+_35731735 0.26 ENSMUST00000236868.2
polyadenylate-binding protein-interacting protein 2
chr5_+_93416091 0.26 ENSMUST00000121127.2
cyclin G2
chr5_+_108609087 0.26 ENSMUST00000112597.8
ENSMUST00000046975.12
polycomb group ring finger 3
chr6_-_52222776 0.26 ENSMUST00000048026.10
homeobox A11
chr3_+_103187162 0.26 ENSMUST00000106860.6
tripartite motif-containing 33
chr13_+_42205790 0.26 ENSMUST00000220525.2
human immunodeficiency virus type I enhancer binding protein 1
chr4_-_34882917 0.26 ENSMUST00000098163.9
ENSMUST00000047950.6
zinc finger protein 292
chr3_-_141637245 0.26 ENSMUST00000106232.8
bone morphogenetic protein receptor, type 1B
chr10_+_102348076 0.26 ENSMUST00000219445.2
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0061181 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.3 1.0 GO:1990697 protein depalmitoleylation(GO:1990697)
0.3 1.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.2 0.7 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.2 0.4 GO:0072240 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.2 0.4 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.2 0.6 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 0.6 GO:1903334 positive regulation of protein folding(GO:1903334)
0.2 0.9 GO:0046684 response to pyrethroid(GO:0046684)
0.2 0.7 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.2 0.5 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.2 0.6 GO:0006227 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1 1.4 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1 0.7 GO:0060431 primary lung bud formation(GO:0060431)
0.1 0.5 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.9 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.5 GO:0071895 odontoblast differentiation(GO:0071895)
0.1 1.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.6 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.1 0.2 GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983)
0.1 0.3 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 0.4 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 1.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.3 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.3 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.3 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.1 2.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.3 GO:2000184 glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) positive regulation of progesterone biosynthetic process(GO:2000184)
0.1 0.5 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.4 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.4 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.4 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.1 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 0.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.4 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.2 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.1 0.5 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.3 GO:0003358 noradrenergic neuron development(GO:0003358)
0.1 0.2 GO:0070237 positive regulation of activation-induced cell death of T cells(GO:0070237) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.1 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.1 GO:0100012 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.1 0.4 GO:0014826 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.1 0.3 GO:0015744 succinate transport(GO:0015744)
0.1 0.1 GO:0060031 planar cell polarity pathway involved in axis elongation(GO:0003402) Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.3 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 0.2 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.4 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 1.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.4 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 0.4 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.6 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.3 GO:0061317 Notch signaling pathway involved in heart induction(GO:0003137) regulation of Notch signaling pathway involved in heart induction(GO:0035480) positive regulation of Notch signaling pathway involved in heart induction(GO:0035481) arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) canonical Wnt signaling pathway involved in heart development(GO:0061316) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of cell adhesion involved in heart morphogenesis(GO:0061344) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.4 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 0.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.2 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.1 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.2 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.1 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.7 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.4 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 1.2 GO:0060065 uterus development(GO:0060065)
0.0 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.2 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.4 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0098963 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.0 0.2 GO:0043366 beta selection(GO:0043366)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.3 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.3 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.5 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.4 GO:0072189 ureter development(GO:0072189)
0.0 0.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.4 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.4 GO:2000794 regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.0 0.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.8 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0 0.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.2 GO:0007527 adult somatic muscle development(GO:0007527)
0.0 0.3 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.8 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 1.4 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.6 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.8 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.4 GO:0045760 positive regulation of action potential(GO:0045760)
0.0 0.1 GO:0060309 elastin catabolic process(GO:0060309)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.6 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.0 0.4 GO:0008272 sulfate transport(GO:0008272)
0.0 0.2 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.2 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 1.7 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.1 GO:0043056 forward locomotion(GO:0043056)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.2 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.0 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.3 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.1 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:0097106 postsynaptic density organization(GO:0097106)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.0 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.3 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:1990403 embryonic brain development(GO:1990403)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 1.0 GO:1903349 omegasome membrane(GO:1903349)
0.1 1.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.7 GO:0044305 calyx of Held(GO:0044305)
0.1 0.5 GO:0031417 NatC complex(GO:0031417)
0.1 0.3 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.1 0.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.3 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0 0.3 GO:0070449 elongin complex(GO:0070449)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0097413 Lewy body(GO:0097413)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 3.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 1.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0002142 stereocilia ankle link complex(GO:0002142)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.2 0.9 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 0.6 GO:0030350 iron-responsive element binding(GO:0030350)
0.2 0.6 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
0.1 0.5 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.8 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 0.4 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.3 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 1.8 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.3 GO:0070905 serine binding(GO:0070905)
0.1 0.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.2 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.2 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.0 0.4 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.0 0.5 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0070401 NADP+ binding(GO:0070401)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.7 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.7 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0042805 actinin binding(GO:0042805)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 6.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.0 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.3 GO:0043425 bHLH transcription factor binding(GO:0043425)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 4.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.1 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.3 ST ADRENERGIC Adrenergic Pathway
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.7 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 0.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling