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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Lhx8

Z-value: 1.87

Motif logo

Transcription factors associated with Lhx8

Gene Symbol Gene ID Gene Info
ENSMUSG00000096225.8 Lhx8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lhx8mm39_v1_chr3_-_154036180_154036296-0.192.7e-01Click!

Activity profile of Lhx8 motif

Sorted Z-values of Lhx8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx8

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_130589349 13.78 ENSMUST00000027657.14
complement component 4 binding protein
chr19_+_39980868 10.36 ENSMUST00000049178.3
cytochrome P450, family 2. subfamily c, polypeptide 37
chr5_-_87572060 9.79 ENSMUST00000072818.6
UDP glucuronosyltransferase 2 family, polypeptide B38
chr1_+_21310803 8.19 ENSMUST00000027067.15
glutathione S-transferase, alpha 3
chr1_+_21310821 7.78 ENSMUST00000121676.8
ENSMUST00000124990.3
glutathione S-transferase, alpha 3
chr3_+_130411097 7.45 ENSMUST00000166187.8
ENSMUST00000072271.13
ethanolamine phosphate phospholyase
chr19_-_4092218 6.51 ENSMUST00000237999.2
ENSMUST00000042700.12
glutathione S-transferase, pi 2
chr3_-_113368407 6.47 ENSMUST00000106540.8
amylase 1, salivary
chr7_-_48493388 5.65 ENSMUST00000167786.4
cysteine and glycine-rich protein 3
chr3_+_130411294 5.39 ENSMUST00000163620.8
ethanolamine phosphate phospholyase
chr5_-_87402659 5.04 ENSMUST00000075858.4
UDP glucuronosyltransferase 2 family, polypeptide B37
chr1_-_72323464 5.02 ENSMUST00000027381.13
peroxisomal trans-2-enoyl-CoA reductase
chr1_-_72323407 4.87 ENSMUST00000097698.5
peroxisomal trans-2-enoyl-CoA reductase
chr5_+_90666791 4.76 ENSMUST00000113179.9
ENSMUST00000128740.2
afamin
chr9_+_118931532 4.71 ENSMUST00000165231.8
ENSMUST00000140326.8
deleted in lung and esophageal cancer 1
chr2_+_172994841 4.58 ENSMUST00000029017.6
phosphoenolpyruvate carboxykinase 1, cytosolic
chr1_+_180878797 4.42 ENSMUST00000036819.7
RIKEN cDNA 9130409I23 gene
chr2_-_110136074 4.20 ENSMUST00000046233.9
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr17_+_79934096 4.17 ENSMUST00000224618.2
regulator of microtubule dynamics 2
chr9_-_43151179 3.97 ENSMUST00000034512.7
out at first homolog
chr10_-_4382311 3.73 ENSMUST00000126102.8
ENSMUST00000131853.2
ENSMUST00000042251.11
required for meiotic nuclear division 1 homolog
chr2_-_52448552 3.67 ENSMUST00000102760.10
ENSMUST00000102761.9
calcium channel, voltage-dependent, beta 4 subunit
chr8_+_46080746 3.45 ENSMUST00000145458.9
ENSMUST00000134321.8
sorbin and SH3 domain containing 2
chr10_-_4382283 3.39 ENSMUST00000155172.8
required for meiotic nuclear division 1 homolog
chr3_+_20011405 2.80 ENSMUST00000108325.9
ceruloplasmin
chr12_+_112940086 2.77 ENSMUST00000165079.8
ENSMUST00000221500.2
ENSMUST00000221104.2
ENSMUST00000002880.7
ENSMUST00000222209.2
BTB (POZ) domain containing 6
chr4_-_96479793 2.61 ENSMUST00000055693.9
cytochrome P450, family 2, subfamily j, polypeptide 9
chr7_-_59654849 2.45 ENSMUST00000059305.17
small nuclear ribonucleoprotein N
chr14_-_30213408 2.24 ENSMUST00000112250.6
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr11_-_12414850 2.08 ENSMUST00000109650.8
cordon-bleu WH2 repeat
chr7_-_59654797 1.99 ENSMUST00000194059.2
SNRPN upstream reading frame
chr6_-_71417607 1.92 ENSMUST00000002292.15
required for meiotic nuclear division 5 homolog A
chr8_+_67933573 1.90 ENSMUST00000212171.2
N-acetyl transferase 1
chr14_+_47069582 1.85 ENSMUST00000068532.10
cell growth regulator with ring finger domain 1
chr3_-_72964276 1.84 ENSMUST00000192477.2
SLIT and NTRK-like family, member 3
chr5_+_137551774 1.76 ENSMUST00000136088.8
ENSMUST00000139395.8
actin-like 6B
chr8_-_41507808 1.75 ENSMUST00000093534.11
mitochondrial tumor suppressor 1
chr6_+_67701864 1.74 ENSMUST00000103304.3
immunoglobulin kappa variable 1-133
chr8_+_124169707 1.71 ENSMUST00000093049.10
ENSMUST00000065534.10
ENSMUST00000001522.10
ENSMUST00000124741.8
ENSMUST00000108832.8
ENSMUST00000132063.8
ENSMUST00000128424.8
differentially expressed in FDCP 8
chr12_-_56583582 1.70 ENSMUST00000001536.9
NK2 homeobox 1
chr1_+_107289659 1.67 ENSMUST00000027566.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr14_+_73380577 1.67 ENSMUST00000165567.8
ENSMUST00000022702.13
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr5_+_137551790 1.61 ENSMUST00000136565.8
ENSMUST00000149292.8
ENSMUST00000125489.2
actin-like 6B
chr16_-_48592319 1.60 ENSMUST00000239408.2
T cell receptor associated transmembrane adaptor 1
chr14_+_73380539 1.60 ENSMUST00000169513.8
ENSMUST00000165727.8
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr11_-_102470287 1.56 ENSMUST00000107081.8
predicted gene 11627
chr4_+_53011880 1.49 ENSMUST00000015391.10
nipsnap homolog 3B
chr4_-_144447974 1.40 ENSMUST00000036876.8
AADACL4 family member 3
chr17_+_24851647 1.40 ENSMUST00000047611.4
nth (endonuclease III)-like 1 (E.coli)
chr16_-_48592372 1.38 ENSMUST00000231701.3
T cell receptor associated transmembrane adaptor 1
chr5_-_145128376 1.30 ENSMUST00000037056.9
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2
chr13_-_66375387 1.29 ENSMUST00000167981.3
predicted gene 10772
chr15_+_54609011 1.26 ENSMUST00000050027.9
cellular communication network factor 3
chr8_+_124170027 1.24 ENSMUST00000108830.2
differentially expressed in FDCP 8
chr11_+_104122341 1.22 ENSMUST00000106993.10
microtubule-associated protein tau
chr1_-_170695328 1.21 ENSMUST00000027974.7
activating transcription factor 6
chr3_-_57599956 1.18 ENSMUST00000238789.2
ENSMUST00000197088.5
ENSMUST00000099091.4
ankrin repeat and ubiquitin domain containing 1
chr3_-_52924616 1.18 ENSMUST00000193432.6
ENSMUST00000195183.2
ENSMUST00000036665.10
component of oligomeric golgi complex 6
chr4_-_95965767 1.15 ENSMUST00000030305.13
ENSMUST00000107078.9
cytochrome P450, family 2, subfamily j, polypeptide 13
chr5_-_145128321 1.15 ENSMUST00000161845.2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2
chr14_+_73380485 1.09 ENSMUST00000170677.8
ENSMUST00000167401.8
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr8_+_72973560 1.08 ENSMUST00000003123.10
family with sequence similarity 32, member A
chr11_-_102469896 1.04 ENSMUST00000107080.2
predicted gene 11627
chr8_+_105558204 1.03 ENSMUST00000059449.7
carboxyesterase 2B
chr6_-_3763618 1.03 ENSMUST00000171613.8
calcitonin receptor
chr15_-_99717956 0.99 ENSMUST00000109024.9
LIM domain and actin binding 1
chr2_+_89842475 0.98 ENSMUST00000214382.2
ENSMUST00000217065.3
olfactory receptor 1263
chr2_+_177200363 0.93 ENSMUST00000108940.3
predicted gene 14403
chr1_+_6557455 0.91 ENSMUST00000140079.8
ENSMUST00000131494.8
suppression of tumorigenicity 18
chr14_+_53743184 0.91 ENSMUST00000103583.5
T cell receptor alpha variable 10
chr14_-_48900192 0.89 ENSMUST00000122009.8
orthodenticle homeobox 2
chr4_-_95965747 0.88 ENSMUST00000097973.3
cytochrome P450, family 2, subfamily j, polypeptide 13
chr13_+_65660492 0.87 ENSMUST00000081471.3
predicted gene 10139
chr6_+_41155309 0.84 ENSMUST00000103276.3
T cell receptor beta, variable 19
chr15_-_103337982 0.84 ENSMUST00000146736.8
gametocyte specific factor 1
chr1_+_33947250 0.82 ENSMUST00000183034.5
dystonin
chr14_+_48683581 0.82 ENSMUST00000227440.2
ENSMUST00000124720.8
ENSMUST00000226422.2
ENSMUST00000226400.2
transmembrane protein 260
chr1_+_163875783 0.82 ENSMUST00000027874.6
selectin, endothelial cell
chr6_+_15185399 0.80 ENSMUST00000115474.8
ENSMUST00000115472.8
ENSMUST00000031545.14
forkhead box P2
chr2_+_73142945 0.78 ENSMUST00000090811.11
ENSMUST00000112050.2
secernin 3
chr14_-_36628263 0.77 ENSMUST00000183007.2
coiled-coil serine rich 2
chr6_+_15184630 0.76 ENSMUST00000115470.3
forkhead box P2
chr12_-_113928438 0.75 ENSMUST00000103478.4
immunoglobulin heavy variable 3-1
chr7_+_19093665 0.75 ENSMUST00000140836.8
protein phosphatase 1, regulatory subunit 13 like
chr2_-_155534295 0.75 ENSMUST00000041059.12
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr6_+_67736650 0.72 ENSMUST00000103305.2
immunoglobulin kappa variable 1-132
chr6_+_15185202 0.72 ENSMUST00000154448.2
forkhead box P2
chr11_+_102175985 0.68 ENSMUST00000156326.2
transmembrane and ubiquitin-like domain containing 2
chr6_-_136150491 0.67 ENSMUST00000111905.8
ENSMUST00000152012.8
ENSMUST00000143943.8
ENSMUST00000125905.2
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr2_+_36263531 0.67 ENSMUST00000072114.4
ENSMUST00000217511.2
olfactory receptor 338
chrM_+_7779 0.65 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chr14_-_7648948 0.65 ENSMUST00000112630.9
ENSMUST00000112631.9
NIMA (never in mitosis gene a)- related kinase 10
chr5_+_34493633 0.60 ENSMUST00000182709.8
ENSMUST00000030992.13
ring finger protein 4
chr1_+_88234454 0.59 ENSMUST00000040210.14
transient receptor potential cation channel, subfamily M, member 8
chr14_+_73380163 0.56 ENSMUST00000170368.8
ENSMUST00000171767.8
ENSMUST00000163533.8
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr2_-_155534235 0.56 ENSMUST00000103140.5
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr11_-_73290321 0.55 ENSMUST00000131253.2
ENSMUST00000120303.9
olfactory receptor 1
chrX_-_162544319 0.52 ENSMUST00000059320.4
ring finger protein 138, retrogene 1
chr10_+_103987773 0.52 ENSMUST00000180692.3
predicted gene 6763
chr10_+_103996282 0.52 ENSMUST00000181166.3
predicted gene 8764
chr10_+_104030318 0.52 ENSMUST00000181036.2
predicted gene 4340
chr10_+_103979263 0.52 ENSMUST00000180664.2
predicted gene, 21293
chr10_+_104004791 0.52 ENSMUST00000180568.2
predicted gene, 21304
chr10_+_104013300 0.52 ENSMUST00000181239.2
predicted gene, 21312
chr10_+_104021809 0.52 ENSMUST00000181707.2
predicted gene, 20765
chr6_-_119085508 0.52 ENSMUST00000188522.7
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr7_+_140261864 0.50 ENSMUST00000214637.3
olfactory receptor 45
chr3_-_94490023 0.49 ENSMUST00000029783.16
sorting nexin family member 27
chr5_-_77053226 0.48 ENSMUST00000135954.2
aminoadipate-semialdehyde dehydrogenase
chr7_+_114318746 0.48 ENSMUST00000182044.2
calcitonin-related polypeptide, beta
chr7_+_90739904 0.46 ENSMUST00000107196.10
ENSMUST00000074273.10
discs large MAGUK scaffold protein 2
chr14_+_53698556 0.46 ENSMUST00000181728.3
T cell receptor alpha variable 7-4
chr12_-_114217671 0.46 ENSMUST00000193408.2
immunoglobulin heavy variable V3-4
chr18_+_23548192 0.46 ENSMUST00000222515.2
dystrobrevin alpha
chr1_+_134313676 0.45 ENSMUST00000162187.2
MGAT4 family, member F
chr17_+_35150229 0.45 ENSMUST00000007253.6
neuraminidase 1
chrM_+_7758 0.45 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr1_+_17215581 0.41 ENSMUST00000026879.8
ganglioside-induced differentiation-associated-protein 1
chr5_-_62923463 0.41 ENSMUST00000076623.8
ENSMUST00000159470.3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_+_137777111 0.41 ENSMUST00000126126.8
ENSMUST00000031739.6
protein phosphatase 1, regulatory subunit 35
chr7_-_3218909 0.41 ENSMUST00000203937.2
expressed sequence AU018091
chr19_-_12302465 0.41 ENSMUST00000207241.3
olfactory receptor 1437
chr15_+_101013619 0.41 ENSMUST00000070875.8
ENSMUST00000231158.2
ankyrin repeat domain 33
chr14_+_61005570 0.40 ENSMUST00000025940.7
C1q and tumor necrosis factor related protein 9
chr9_+_37400317 0.39 ENSMUST00000239459.2
Myb/SANT-like DNA-binding domain containing 2
chr2_+_153785839 0.39 ENSMUST00000099181.2
BPI fold containing family B, member 4
chr15_+_101013704 0.37 ENSMUST00000229954.2
ankyrin repeat domain 33
chr18_+_23548534 0.37 ENSMUST00000221880.2
ENSMUST00000220904.2
ENSMUST00000047954.15
dystrobrevin alpha
chrX_-_156198282 0.36 ENSMUST00000079945.11
ENSMUST00000138396.3
phosphate regulating endopeptidase homolog, X-linked
chr5_+_124068728 0.36 ENSMUST00000094320.10
ENSMUST00000165148.4
coiled-coil domain containing 62
chr2_-_113844100 0.34 ENSMUST00000090275.5
gap junction protein, delta 2
chr1_-_59200718 0.32 ENSMUST00000078874.14
ENSMUST00000066374.14
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr7_-_3218968 0.32 ENSMUST00000171749.3
expressed sequence AU018091
chr18_+_23548455 0.32 ENSMUST00000115832.4
dystrobrevin alpha
chr7_-_106709576 0.31 ENSMUST00000215713.2
olfactory receptor 715B
chr3_-_30654012 0.30 ENSMUST00000047630.7
actin related protein T3
chr12_-_73093953 0.30 ENSMUST00000050029.8
sine oculis-related homeobox 1
chr16_+_35361635 0.28 ENSMUST00000120756.8
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr5_-_77053310 0.28 ENSMUST00000146570.8
ENSMUST00000142450.2
ENSMUST00000120963.8
aminoadipate-semialdehyde dehydrogenase
chr19_+_44748354 0.27 ENSMUST00000173346.4
paired box 2
chr3_-_82957104 0.26 ENSMUST00000048246.5
fibrinogen beta chain
chr12_-_113379925 0.26 ENSMUST00000194162.6
ENSMUST00000192250.2
immunoglobulin heavy constant delta
chr10_+_104029903 0.24 ENSMUST00000181615.8
predicted gene 4340
chr10_+_103978848 0.24 ENSMUST00000181634.8
predicted gene, 21293
chr10_+_103987358 0.24 ENSMUST00000181287.5
predicted gene 6763
chr10_+_103995867 0.24 ENSMUST00000181179.5
predicted gene 8764
chr10_+_104004376 0.24 ENSMUST00000181059.8
predicted gene, 21304
chr10_+_104012885 0.24 ENSMUST00000180889.8
predicted gene, 21312
chr10_+_104021394 0.24 ENSMUST00000181703.8
predicted gene, 20765
chr13_+_23431304 0.24 ENSMUST00000235331.2
ENSMUST00000236495.2
ENSMUST00000238002.2
vomeronasal 1 receptor 223
chr7_+_43701714 0.24 ENSMUST00000079859.7
kallikrein 1-related peptidase b27
chr14_+_48683797 0.24 ENSMUST00000111735.10
transmembrane protein 260
chr1_+_92545510 0.23 ENSMUST00000213247.2
olfactory receptor 12
chr10_-_17898977 0.23 ENSMUST00000020002.9
ABRA C-terminal like
chr3_+_107198528 0.23 ENSMUST00000029502.14
solute carrier family 16 (monocarboxylic acid transporters), member 4
chr19_-_34579356 0.21 ENSMUST00000168254.3
interferon induced protein with tetratricpeptide repeats 1B like 1
chr2_-_34760960 0.21 ENSMUST00000028225.12
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
chr9_+_58036759 0.21 ENSMUST00000133287.8
stimulated by retinoic acid gene 6
chr13_+_23953896 0.20 ENSMUST00000226039.2
tripartite motif-containing 38
chr8_+_89309408 0.20 ENSMUST00000211113.2
naked cuticle 1
chr7_-_12002196 0.20 ENSMUST00000227973.2
ENSMUST00000228764.2
ENSMUST00000228482.2
ENSMUST00000227080.2
vomeronasal 1 receptor 81
chr9_+_58036604 0.20 ENSMUST00000034880.10
stimulated by retinoic acid gene 6
chr15_+_21111428 0.19 ENSMUST00000075132.8
cadherin 12
chr9_-_78285942 0.19 ENSMUST00000034900.8
oocyte expressed protein
chr4_-_155729865 0.19 ENSMUST00000115821.3
predicted gene 10563
chr7_-_130931235 0.18 ENSMUST00000188899.2
family with sequence similarity 24 member B
chr14_+_53048391 0.17 ENSMUST00000103646.5
T cell receptor alpha variable 10D
chr15_-_101441254 0.17 ENSMUST00000023720.8
keratin 84
chr1_-_134477400 0.16 ENSMUST00000172898.2
MGAT4 family, member E
chr7_-_104677667 0.16 ENSMUST00000215899.2
ENSMUST00000214318.3
olfactory receptor 675
chr9_+_38202403 0.15 ENSMUST00000216276.2
ENSMUST00000215219.2
olfactory receptor 896, pseudogene 1
chrX_+_149372903 0.14 ENSMUST00000080884.11
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr8_-_95929420 0.14 ENSMUST00000212842.2
kinesin family member C3
chr11_+_16207705 0.13 ENSMUST00000109645.9
ENSMUST00000109647.3
V-set and transmembrane domain containing 2A
chr15_-_98118858 0.13 ENSMUST00000142443.8
ENSMUST00000170618.8
predicted gene 44579
olfactory receptor 287
chr3_-_100592747 0.13 ENSMUST00000008907.14
mannosidase, alpha, class 1A, member 2
chr7_-_106563137 0.12 ENSMUST00000213552.2
ENSMUST00000040983.6
ENSMUST00000213651.2
olfactory receptor 6
chr10_-_129448439 0.11 ENSMUST00000214584.3
olfactory receptor 796
chr2_-_13798843 0.10 ENSMUST00000003509.10
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr5_-_109207435 0.09 ENSMUST00000164875.3
vomeronasal 2, receptor 11
chr13_-_21744063 0.07 ENSMUST00000217519.2
olfactory receptor 1535
chr2_+_112114906 0.06 ENSMUST00000053666.8
solute carrier family 12, member 6
chr10_+_5589210 0.05 ENSMUST00000019906.6
vasoactive intestinal polypeptide
chr14_+_53007210 0.05 ENSMUST00000178768.4
T cell receptor alpha variable 7D-4
chr9_+_7344357 0.04 ENSMUST00000150167.2
ENSMUST00000120655.8
matrix metallopeptidase 12
chr2_+_21210527 0.03 ENSMUST00000054591.10
ENSMUST00000102952.8
ENSMUST00000138965.8
ENSMUST00000138914.8
ENSMUST00000102951.2
threonine synthase-like 1 (bacterial)
chr11_-_75828504 0.03 ENSMUST00000108420.9
rabphilin 3A-like (without C2 domains)
chr16_+_23247883 0.01 ENSMUST00000038730.7
receptor transporter protein 1
chr7_-_104628324 0.01 ENSMUST00000217091.2
ENSMUST00000210963.3
olfactory receptor 671
chr5_-_76511634 0.00 ENSMUST00000031146.3
neuromedin U

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 16.0 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377)
3.3 9.9 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
1.9 5.6 GO:1903920 positive regulation of actin filament severing(GO:1903920)
1.1 4.6 GO:0061402 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
1.1 4.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.6 1.7 GO:0021759 globus pallidus development(GO:0021759)
0.5 7.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.5 3.0 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.5 1.4 GO:0006285 base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.4 2.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 10.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.3 3.7 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 2.1 GO:0001757 somite specification(GO:0001757)
0.2 0.8 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.9 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 2.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.7 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 1.2 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 0.3 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.3 GO:0061360 optic nerve formation(GO:0021634) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.1 4.8 GO:0051180 vitamin transport(GO:0051180)
0.1 0.5 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 0.6 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 1.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 2.8 GO:0046688 response to copper ion(GO:0046688)
0.1 6.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 4.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.6 GO:0050955 thermoception(GO:0050955)
0.1 0.4 GO:0009313 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.1 8.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.9 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.4 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 3.4 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 1.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 3.6 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 5.3 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.0 0.8 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.7 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.8 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 1.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.3 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.5 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.1 GO:0006000 fructose metabolic process(GO:0006000)
0.0 4.7 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.5 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 1.0 GO:0031529 ruffle organization(GO:0031529)
0.0 1.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.0 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.4 1.9 GO:0034657 GID complex(GO:0034657)
0.4 1.1 GO:0016014 dystrobrevin complex(GO:0016014)
0.2 2.1 GO:1990357 terminal web(GO:1990357)
0.2 3.6 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.2 2.4 GO:0005687 U4 snRNP(GO:0005687)
0.2 2.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.2 GO:0045298 tubulin complex(GO:0045298)
0.1 3.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 1.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.8 GO:0031673 H zone(GO:0031673)
0.1 9.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 3.0 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.2 GO:0017119 Golgi transport complex(GO:0017119)
0.1 3.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.5 GO:0071203 WASH complex(GO:0071203)
0.0 2.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 5.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 4.4 GO:0030018 Z disc(GO:0030018)
0.0 1.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 12.8 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
2.5 9.9 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
2.2 6.5 GO:0035730 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
1.6 4.8 GO:0008431 vitamin E binding(GO:0008431)
1.5 4.6 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.1 4.4 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.9 6.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.8 5.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.7 2.2 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.4 1.9 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.4 14.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.4 1.4 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.3 1.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.3 16.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.3 10.4 GO:0070330 aromatase activity(GO:0070330)
0.3 2.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.2 GO:0099609 microtubule lateral binding(GO:0099609)
0.2 4.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 0.6 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.8 GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity(GO:0004043)
0.1 1.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.4 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.7 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.8 GO:0033691 sialic acid binding(GO:0033691)
0.1 3.1 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 4.2 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.8 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 2.0 GO:0051117 ATPase binding(GO:0051117)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 2.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.7 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 16.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 4.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 2.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 3.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway