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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Maf_Nrl

Z-value: 2.49

Motif logo

Transcription factors associated with Maf_Nrl

Gene Symbol Gene ID Gene Info
ENSMUSG00000055435.7 Maf
ENSMUSG00000040632.17 Nrl

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nrlmm39_v1_chr14_-_55762416_55762423-0.643.1e-05Click!
Mafmm39_v1_chr8_-_116433733_116433835-0.626.3e-05Click!

Activity profile of Maf_Nrl motif

Sorted Z-values of Maf_Nrl motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Maf_Nrl

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_87695352 24.48 ENSMUST00000121952.8
ENSMUST00000126490.8
insulin-like growth factor 1
chr10_+_87695886 21.32 ENSMUST00000062862.13
insulin-like growth factor 1
chr7_+_26821266 19.52 ENSMUST00000206552.2
cytochrome P450, family 2, subfamily f, polypeptide 2
chr9_-_46146558 15.29 ENSMUST00000121916.8
ENSMUST00000034586.9
apolipoprotein C-III
chr19_+_38995463 14.89 ENSMUST00000025966.5
cytochrome P450, family 2, subfamily c, polypeptide 55
chr19_+_20579322 13.06 ENSMUST00000087638.4
aldehyde dehydrogenase family 1, subfamily A1
chr10_+_87695117 12.81 ENSMUST00000105300.9
insulin-like growth factor 1
chr19_-_20704896 11.64 ENSMUST00000025656.4
aldehyde dehydrogenase family 1, subfamily A7
chr10_+_87696339 11.34 ENSMUST00000121161.8
insulin-like growth factor 1
chr4_+_104623505 10.59 ENSMUST00000031663.10
ENSMUST00000065072.7
complement component 8, beta polypeptide
chr10_+_87694924 10.36 ENSMUST00000095360.11
insulin-like growth factor 1
chr9_-_46146928 8.77 ENSMUST00000118649.8
apolipoprotein C-III
chr16_-_45975440 7.31 ENSMUST00000059524.7
predicted gene 4737
chr5_-_77262968 4.92 ENSMUST00000081964.7
HOP homeobox
chr4_+_140970161 4.64 ENSMUST00000138096.8
ENSMUST00000006618.9
ENSMUST00000125392.8
Rho guanine nucleotide exchange factor (GEF) 19
chr19_-_4087907 4.53 ENSMUST00000237982.2
glutathione S-transferase, pi 1
chr19_-_4087940 4.48 ENSMUST00000237893.2
ENSMUST00000169613.4
glutathione S-transferase, pi 1
chr1_+_127657142 4.10 ENSMUST00000038006.8
amino carboxymuconate semialdehyde decarboxylase
chr19_-_4092218 4.09 ENSMUST00000237999.2
ENSMUST00000042700.12
glutathione S-transferase, pi 2
chr15_+_10224052 4.06 ENSMUST00000128450.8
ENSMUST00000148257.8
ENSMUST00000128921.8
prolactin receptor
chr19_-_21630143 3.36 ENSMUST00000179768.8
ENSMUST00000178523.2
ENSMUST00000038830.10
RIKEN cDNA 1110059E24 gene
chr4_-_82623972 3.17 ENSMUST00000155821.2
nuclear factor I/B
chr8_+_120163857 2.86 ENSMUST00000152420.8
ENSMUST00000212112.2
ENSMUST00000098365.4
oxidative stress induced growth inhibitor 1
chr6_+_129510331 2.62 ENSMUST00000204956.2
ENSMUST00000204639.2
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr7_+_100970435 2.62 ENSMUST00000210192.2
ENSMUST00000172630.8
START domain containing 10
chr6_+_83031502 2.41 ENSMUST00000092618.9
ancient ubiquitous protein 1
chr17_-_24428351 2.39 ENSMUST00000024931.6
netrin 3
chr17_-_34250474 2.37 ENSMUST00000171872.3
ENSMUST00000025186.16
solute carrier family 39 (zinc transporter), member 7
chr18_-_35760260 2.35 ENSMUST00000025212.8
solute carrier family 23 (nucleobase transporters), member 1
chr13_-_64277115 2.34 ENSMUST00000220792.2
ENSMUST00000222866.2
ENSMUST00000099441.6
ENSMUST00000222168.2
solute carrier family 35, member D2
chr11_-_53313950 2.31 ENSMUST00000036045.6
liver-expressed antimicrobial peptide 2
chr17_-_34250616 2.31 ENSMUST00000169397.9
solute carrier family 39 (zinc transporter), member 7
chr4_-_41741278 2.30 ENSMUST00000059354.15
ENSMUST00000071561.7
sigma non-opioid intracellular receptor 1
chr7_+_100971034 2.26 ENSMUST00000173270.8
START domain containing 10
chr5_-_24628514 2.19 ENSMUST00000030814.11
cyclin-dependent kinase 5
chr14_+_67470884 2.19 ENSMUST00000176161.8
early B cell factor 2
chr7_+_100970910 2.17 ENSMUST00000174291.8
ENSMUST00000167888.9
ENSMUST00000172662.2
START domain containing 10
chr14_-_73622638 2.16 ENSMUST00000228637.2
ENSMUST00000022704.9
integral membrane protein 2B
chr2_-_32584132 2.14 ENSMUST00000028148.11
folylpolyglutamyl synthetase
chr16_-_56987670 2.12 ENSMUST00000023432.10
nitrilase family, member 2
chr6_-_138013901 2.11 ENSMUST00000150278.3
solute carrier family 15, member 5
chr11_+_80319424 2.08 ENSMUST00000173938.8
ENSMUST00000017572.14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr6_+_90439544 2.04 ENSMUST00000032174.12
Kruppel-like factor 15
chr18_+_5593566 2.02 ENSMUST00000160910.2
zinc finger E-box binding homeobox 1
chr18_-_43192483 2.00 ENSMUST00000025377.14
protein phosphatase 2, regulatory subunit B, beta
chr13_+_64309675 1.99 ENSMUST00000021929.10
hyaluronic acid binding protein 4
chr17_-_25394445 1.94 ENSMUST00000224277.2
proline and glutamate rich with coiled coil 1
chr2_+_34661982 1.93 ENSMUST00000028222.13
ENSMUST00000100171.3
heat shock protein 5
chr7_+_18962252 1.88 ENSMUST00000063976.9
optic atrophy 3
chr12_+_10440755 1.88 ENSMUST00000020947.7
retinol dehydrogenase 14 (all-trans and 9-cis)
chr6_+_90439596 1.88 ENSMUST00000203039.3
Kruppel-like factor 15
chr4_-_6275629 1.88 ENSMUST00000029905.2
cytochrome P450, family 7, subfamily a, polypeptide 1
chr10_-_24588030 1.79 ENSMUST00000105520.8
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr9_+_44966464 1.78 ENSMUST00000114664.8
myelin protein zero-like 3
chr18_-_35788255 1.73 ENSMUST00000190196.5
proline rich basic protein 1
chr9_+_110074574 1.68 ENSMUST00000197850.5
chondroitin sulfate proteoglycan 5
chr4_+_84802592 1.67 ENSMUST00000102819.10
centlein, centrosomal protein
chr4_-_63072367 1.65 ENSMUST00000030041.5
alpha 1 microglobulin/bikunin precursor
chr1_-_74932266 1.63 ENSMUST00000006721.3
crystallin, beta A2
chr3_+_95801325 1.61 ENSMUST00000197081.2
ENSMUST00000056710.10
aph1 homolog A, gamma secretase subunit
chr4_+_56740070 1.59 ENSMUST00000181745.2
predicted gene, 26657
chr9_-_107556823 1.58 ENSMUST00000010205.9
guanine nucleotide binding protein, alpha transducing 1
chr3_-_33137209 1.57 ENSMUST00000194016.6
ENSMUST00000193681.6
ENSMUST00000192093.6
ENSMUST00000193289.6
peroxisomal biogenesis factor 5-like
chr1_-_66974694 1.54 ENSMUST00000186202.7
myosin, light polypeptide 1
chr2_+_152873772 1.51 ENSMUST00000037235.7
X-linked Kx blood group related 7
chr14_+_73790105 1.50 ENSMUST00000160507.8
ENSMUST00000022706.7
succinate-Coenzyme A ligase, ADP-forming, beta subunit
chr18_+_21134928 1.49 ENSMUST00000234536.2
ENSMUST00000052396.7
ring finger protein 138
chr3_-_58433313 1.49 ENSMUST00000029385.9
stress-associated endoplasmic reticulum protein 1
chr15_+_57558048 1.48 ENSMUST00000096430.11
zinc fingers and homeoboxes 2
chr17_-_13271183 1.48 ENSMUST00000091648.4
G protein-coupled receptor 31, D17Leh66b region
chr9_-_106124917 1.47 ENSMUST00000112524.9
ENSMUST00000219129.2
aminolevulinic acid synthase 1
chr13_+_42862957 1.47 ENSMUST00000066928.12
ENSMUST00000148891.8
phosphatase and actin regulator 1
chr9_+_46139878 1.44 ENSMUST00000034588.9
ENSMUST00000132155.2
apolipoprotein A-I
chr2_-_156728988 1.44 ENSMUST00000029164.9
Src-like-adaptor 2
chr4_+_59003121 1.44 ENSMUST00000095070.4
ENSMUST00000174664.2
DnaJ heat shock protein family (Hsp40) member C25
predicted gene 20503
chr1_-_183150867 1.41 ENSMUST00000194543.4
melanoma inhibitory activity 3
chr2_-_156729092 1.41 ENSMUST00000109561.4
Src-like-adaptor 2
chr5_+_110692162 1.39 ENSMUST00000040001.14
polypeptide N-acetylgalactosaminyltransferase 9
chr1_+_186699613 1.39 ENSMUST00000045108.2
DNA segment, Chr 1, Pasteur Institute 1
chr9_-_63306497 1.38 ENSMUST00000168665.3
RIKEN cDNA 2300009A05 gene
chr1_-_20854490 1.35 ENSMUST00000039046.10
interleukin 17F
chr3_-_33137165 1.35 ENSMUST00000078226.10
ENSMUST00000108224.8
peroxisomal biogenesis factor 5-like
chr18_+_21135079 1.33 ENSMUST00000234545.2
ring finger protein 138
chr3_+_40905216 1.33 ENSMUST00000191872.6
ENSMUST00000200432.2
La ribonucleoprotein domain family, member 1B
chr3_-_49711765 1.31 ENSMUST00000035931.13
protocadherin 18
chr7_+_18962301 1.31 ENSMUST00000161711.2
optic atrophy 3
chr18_-_35788240 1.31 ENSMUST00000097619.2
proline rich basic protein 1
chr17_-_26288447 1.30 ENSMUST00000122103.9
ENSMUST00000120691.9
RAB11 family interacting protein 3 (class II)
chr14_+_54491637 1.29 ENSMUST00000180359.8
ENSMUST00000199338.2
abhydrolase domain containing 4
chr5_-_30401416 1.27 ENSMUST00000125367.4
adhesion G protein-coupled receptor F3
chr8_+_127898139 1.25 ENSMUST00000238870.2
par-3 family cell polarity regulator
chr12_+_108859557 1.22 ENSMUST00000221377.2
WD repeat domain 25
chr3_-_84128160 1.22 ENSMUST00000154152.2
ENSMUST00000107693.9
ENSMUST00000107695.9
tripartite motif-containing 2
chr4_-_57300361 1.21 ENSMUST00000153926.8
protein tyrosine phosphatase, non-receptor type 3
chr6_-_29380423 1.21 ENSMUST00000147483.3
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
chr5_-_113229445 1.21 ENSMUST00000131708.2
ENSMUST00000117143.8
ENSMUST00000119627.8
crystallin, beta B3
chr3_+_95190255 1.19 ENSMUST00000039537.14
ENSMUST00000107187.9
MINDY lysine 48 deubiquitinase 1
chr13_-_53627110 1.18 ENSMUST00000021922.10
msh homeobox 2
chr10_+_86541675 1.17 ENSMUST00000075632.14
ENSMUST00000217747.2
ENSMUST00000061458.9
tetratricopeptide repeat domain 41
chr9_-_57513510 1.17 ENSMUST00000215487.2
ENSMUST00000045068.10
complexin 3
chr10_+_4660119 1.15 ENSMUST00000105588.8
ENSMUST00000105589.2
estrogen receptor 1 (alpha)
chr10_-_23985432 1.14 ENSMUST00000041180.7
trace amine-associated receptor 9
chr11_+_69214895 1.14 ENSMUST00000060956.13
trafficking protein particle complex 1
chr12_+_80690985 1.13 ENSMUST00000219405.2
ENSMUST00000085245.7
solute carrier family 39 (zinc transporter), member 9
chr2_+_6327431 1.12 ENSMUST00000114937.8
USP6 N-terminal like
chr3_-_49711706 1.12 ENSMUST00000191794.2
protocadherin 18
chr15_+_89338116 1.12 ENSMUST00000023291.6
mitogen-activated protein kinase 8 interacting protein 2
chr5_-_24628483 1.12 ENSMUST00000198990.2
cyclin-dependent kinase 5
chr16_-_92622659 1.11 ENSMUST00000186296.2
runt related transcription factor 1
chr7_-_126062272 1.10 ENSMUST00000032974.13
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr8_-_3928495 1.06 ENSMUST00000209176.2
ENSMUST00000011445.8
CD209d antigen
chr17_+_12803019 1.05 ENSMUST00000046959.9
ENSMUST00000233066.2
solute carrier family 22 (organic cation transporter), member 2
chr17_-_45125468 1.05 ENSMUST00000159943.8
ENSMUST00000160673.8
runt related transcription factor 2
chr2_+_125876883 1.04 ENSMUST00000110442.2
fibroblast growth factor 7
chr5_+_31274064 1.04 ENSMUST00000202769.2
tripartite motif-containing 54
chr11_-_100139728 1.03 ENSMUST00000007280.9
keratin 16
chr11_-_86574586 1.03 ENSMUST00000018315.10
vacuole membrane protein 1
chr11_+_99770013 1.03 ENSMUST00000078442.4
predicted gene 11567
chr5_-_25113358 1.02 ENSMUST00000114975.8
ENSMUST00000150135.8
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr11_+_69214883 1.02 ENSMUST00000102601.10
trafficking protein particle complex 1
chr6_+_115908709 1.01 ENSMUST00000032471.9
rhodopsin
chr8_-_23680954 1.00 ENSMUST00000209507.2
glycerol-3-phosphate acyltransferase 4
chr13_+_84370405 0.99 ENSMUST00000057495.10
ENSMUST00000225069.2
transmembrane protein 161B
chr6_+_110622533 0.99 ENSMUST00000071076.13
ENSMUST00000172951.2
glutamate receptor, metabotropic 7
chr6_-_29380467 0.98 ENSMUST00000080428.13
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
chr8_-_3976808 0.98 ENSMUST00000188386.2
ENSMUST00000084086.9
ENSMUST00000171635.8
CD209b antigen
chr2_+_58991352 0.95 ENSMUST00000037903.15
plakophilin 4
chr17_-_45125537 0.95 ENSMUST00000113571.10
runt related transcription factor 2
chr12_-_28602302 0.95 ENSMUST00000020963.8
ENSMUST00000221349.2
doublecortin domain containing 2C
chr5_-_77555881 0.93 ENSMUST00000163898.6
ENSMUST00000046746.10
insulin-like growth factor binding protein 7
chr2_+_181405106 0.93 ENSMUST00000081125.11
myelin transcription factor 1
chr16_+_20367327 0.92 ENSMUST00000003319.6
ENSMUST00000232680.2
ENSMUST00000232490.2
ATP-binding cassette, sub-family F (GCN20), member 3
chr5_+_31274046 0.92 ENSMUST00000013771.15
tripartite motif-containing 54
chr1_+_85949827 0.91 ENSMUST00000131151.3
spermatogenesis associated 3
chr16_-_15681145 0.91 ENSMUST00000229680.2
mitotic spindle organizing protein 2
chr5_+_102992873 0.90 ENSMUST00000070000.6
Rho GTPase activating protein 24
chr7_-_79036222 0.90 ENSMUST00000205638.2
ENSMUST00000206320.3
ENSMUST00000205442.2
retinaldehyde binding protein 1
chr14_-_63402374 0.90 ENSMUST00000238526.2
farnesyl diphosphate farnesyl transferase 1
chr15_-_85387428 0.90 ENSMUST00000178942.2
RIKEN cDNA 7530416G11 gene
chr7_+_98916677 0.89 ENSMUST00000127492.2
microtubule-associated protein 6
chr16_+_20491465 0.88 ENSMUST00000044783.14
ENSMUST00000115463.8
ENSMUST00000142344.8
ENSMUST00000073840.12
ENSMUST00000143939.8
ENSMUST00000128594.8
ENSMUST00000150333.8
ENSMUST00000231618.2
ENSMUST00000140576.8
ENSMUST00000115457.8
eukaryotic translation initiation factor 4, gamma 1
chrX_+_70860378 0.87 ENSMUST00000114575.4
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr12_+_108860192 0.86 ENSMUST00000220667.2
ENSMUST00000167816.8
ENSMUST00000047115.9
WD repeat domain 25
chr11_+_69214789 0.85 ENSMUST00000102602.8
trafficking protein particle complex 1
chr14_-_34310637 0.85 ENSMUST00000227819.2
LIM domain binding 3
chr7_+_27770655 0.85 ENSMUST00000138392.8
ENSMUST00000076648.8
Fc fragment of IgG binding protein
chr1_-_65142521 0.84 ENSMUST00000061497.9
crystallin, gamma A
chr16_-_62667307 0.82 ENSMUST00000232561.2
ENSMUST00000089289.6
ADP-ribosylation factor-like 13B
chr17_-_35391583 0.82 ENSMUST00000173106.2
allograft inflammatory factor 1
chr1_-_167294349 0.80 ENSMUST00000036643.6
leucine rich repeat containing 52
chr11_+_69214971 0.79 ENSMUST00000108662.2
trafficking protein particle complex 1
chrX_+_70860357 0.79 ENSMUST00000114576.9
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr2_-_26028814 0.79 ENSMUST00000163836.2
transmembrane protein 250, pseudogene
chr3_+_99203818 0.79 ENSMUST00000150756.3
T-box 15
chr9_+_7272514 0.79 ENSMUST00000015394.10
matrix metallopeptidase 13
chr16_+_17149235 0.78 ENSMUST00000023450.15
ENSMUST00000231884.2
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr3_+_45332831 0.77 ENSMUST00000193252.2
ENSMUST00000171554.8
ENSMUST00000166126.7
ENSMUST00000170695.4
protocadherin 10
chr13_+_83720484 0.77 ENSMUST00000196207.5
myocyte enhancer factor 2C
chr3_+_135531834 0.76 ENSMUST00000029810.6
solute carrier family 39 (metal ion transporter), member 8
chr1_+_173877941 0.76 ENSMUST00000062665.4
olfactory receptor 432
chr12_-_90705212 0.75 ENSMUST00000082432.6
deiodinase, iodothyronine, type II
chr10_+_34359513 0.75 ENSMUST00000170771.3
fyn-related kinase
chr2_-_29983618 0.75 ENSMUST00000081838.7
ENSMUST00000102865.11
zinc finger, DHHC domain containing 12
chr11_-_106192627 0.74 ENSMUST00000103071.4
growth hormone
chr14_-_34310602 0.74 ENSMUST00000064098.14
ENSMUST00000090040.12
ENSMUST00000022330.9
ENSMUST00000022327.13
LIM domain binding 3
chr2_+_78699360 0.73 ENSMUST00000028398.14
ubiquitin-conjugating enzyme E2E 3
chr5_-_31117617 0.73 ENSMUST00000202567.2
ENSMUST00000074840.12
prolactin regulatory element binding
chr12_-_85871281 0.72 ENSMUST00000021676.12
ENSMUST00000142331.2
ergosterol biosynthesis 28
chr7_-_79036654 0.72 ENSMUST00000206695.2
retinaldehyde binding protein 1
chrX_-_103900834 0.72 ENSMUST00000033575.7
MAGE family member E2
chrX_-_90619517 0.72 ENSMUST00000078832.5
RIKEN cDNA 1700084M14 gene
chr11_+_60913386 0.71 ENSMUST00000089184.11
potassium inwardly-rectifying channel, subfamily J, member 12
chr12_+_35097179 0.70 ENSMUST00000163677.3
ENSMUST00000048519.17
sorting nexin 13
chr15_-_76084776 0.70 ENSMUST00000169108.8
ENSMUST00000170728.8
plectin
chr14_-_54491365 0.70 ENSMUST00000128231.2
defender against cell death 1
chr7_+_27196760 0.69 ENSMUST00000238964.2
periaxin
chrX_-_18327610 0.69 ENSMUST00000044188.5
divergent protein kinase domain 2B
chr12_+_30634425 0.69 ENSMUST00000057151.10
transmembrane protein 18
chr4_+_123010035 0.68 ENSMUST00000102648.6
3-oxoacid CoA transferase 2B
chr14_-_34310438 0.68 ENSMUST00000228044.2
ENSMUST00000022328.14
LIM domain binding 3
chr3_-_64417263 0.67 ENSMUST00000177184.9
vomeronasal 2, receptor 5
chr8_-_11528615 0.67 ENSMUST00000033900.7
RAB20, member RAS oncogene family
chr7_+_97049210 0.66 ENSMUST00000032882.9
ENSMUST00000149122.2
NADH:ubiquinone oxidoreductase subunit C2
chr6_-_120470768 0.66 ENSMUST00000178687.2
transmembrane protein 121B
chr4_+_143076327 0.65 ENSMUST00000052458.3
leucine rich repeat containing 38
chr9_+_103879745 0.65 ENSMUST00000035167.15
ENSMUST00000194774.6
nephronophthisis 3 (adolescent)
chr19_-_24839219 0.65 ENSMUST00000047666.5
phosphoglucomutase 5
chr2_-_167030706 0.64 ENSMUST00000207917.2
potassium voltage gated channel, Shab-related subfamily, member 1
chr19_+_38253105 0.64 ENSMUST00000196090.2
leucine-rich repeat LGI family, member 1
chr18_-_60866186 0.64 ENSMUST00000237885.2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr8_+_122996308 0.64 ENSMUST00000055537.3
zinc finger protein 469
chr9_-_34967081 0.64 ENSMUST00000215463.2
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr4_+_129878627 0.63 ENSMUST00000120204.8
adhesion G protein-coupled receptor B2
chr11_-_77616103 0.63 ENSMUST00000078623.5
crystallin, beta A1
chr19_+_38253077 0.62 ENSMUST00000198045.5
leucine-rich repeat LGI family, member 1
chr4_-_123217391 0.62 ENSMUST00000102640.2
3-oxoacid CoA transferase 2A
chr9_-_87613301 0.61 ENSMUST00000034991.8
T-box18
chr6_-_56339251 0.61 ENSMUST00000166102.8
phosphodiesterase 1C
chr2_+_125876566 0.61 ENSMUST00000064794.14
fibroblast growth factor 7
chr1_-_136188611 0.61 ENSMUST00000086395.7
G protein-coupled receptor 25

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.5 80.3 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
6.5 19.5 GO:0018931 naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
6.0 24.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
3.0 9.0 GO:2000469 negative regulation of peroxidase activity(GO:2000469)
1.5 13.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.2 14.9 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.8 3.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.8 7.0 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.8 2.3 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.7 2.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.7 11.9 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.7 4.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.7 4.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.6 1.9 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.6 10.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.6 1.7 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.5 1.6 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.4 3.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.4 1.2 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.4 1.9 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.4 1.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.4 1.1 GO:0090076 maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
0.4 5.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.4 1.4 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.3 1.4 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336) positive regulation of progesterone secretion(GO:2000872)
0.3 2.8 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.3 3.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.3 1.4 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.3 0.8 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
0.3 2.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.3 1.6 GO:0050917 sensory perception of umami taste(GO:0050917) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.3 1.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.3 1.0 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.2 2.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.2 1.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 1.2 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.2 1.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.2 5.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.2 0.6 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 0.8 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.2 0.8 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.2 0.5 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.2 1.3 GO:0003383 apical constriction(GO:0003383)
0.2 1.8 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.2 0.5 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.2 0.5 GO:1901147 optic nerve formation(GO:0021634) pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) optic chiasma development(GO:0061360) kidney field specification(GO:0072004) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.2 2.0 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 1.5 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.2 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.2 4.9 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.2 2.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 1.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 2.9 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.2 0.6 GO:0043056 forward locomotion(GO:0043056)
0.1 1.0 GO:0001878 response to yeast(GO:0001878)
0.1 1.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 2.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 2.1 GO:0043248 proteasome assembly(GO:0043248)
0.1 3.9 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.4 GO:0002501 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.5 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 1.3 GO:0045414 regulation of interleukin-8 biosynthetic process(GO:0045414)
0.1 1.7 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.7 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 1.1 GO:0046958 nonassociative learning(GO:0046958)
0.1 2.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.5 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.4 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 3.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 1.9 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.7 GO:0090383 phagosome acidification(GO:0090383)
0.1 1.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.6 GO:0071910 determination of pancreatic left/right asymmetry(GO:0035469) maintenance of organ identity(GO:0048496) determination of liver left/right asymmetry(GO:0071910)
0.1 0.8 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.1 0.9 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 2.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.6 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 1.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.3 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.6 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.7 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 1.2 GO:0015695 organic cation transport(GO:0015695)
0.1 2.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 1.8 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 1.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.3 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 2.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.2 GO:0033967 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 1.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.4 GO:0046618 xenobiotic transport(GO:0042908) drug export(GO:0046618)
0.1 0.3 GO:1904306 positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.1 0.8 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.7 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527)
0.1 0.4 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 0.8 GO:0051546 keratinocyte migration(GO:0051546)
0.1 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.2 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.3 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 0.3 GO:0009624 response to nematode(GO:0009624)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 4.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.0 GO:0071260 hyaluronan metabolic process(GO:0030212) cellular response to mechanical stimulus(GO:0071260)
0.0 0.4 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.4 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093) histone H2A K63-linked ubiquitination(GO:0070535)
0.0 1.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 2.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.7 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 2.4 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 3.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.7 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.2 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.6 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.3 GO:0060746 parental behavior(GO:0060746)
0.0 1.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.0 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.4 GO:0021559 trigeminal nerve development(GO:0021559)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 5.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.5 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.5 GO:0030049 muscle filament sliding(GO:0030049)
0.0 0.1 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.4 GO:0006968 cellular defense response(GO:0006968)
0.0 0.5 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 2.9 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 1.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.7 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.4 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 1.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.6 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.4 GO:0031424 keratinization(GO:0031424)
0.0 0.7 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.7 GO:0035019 somatic stem cell population maintenance(GO:0035019)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.0 80.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
2.6 13.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
2.1 23.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.2 10.6 GO:0005579 membrane attack complex(GO:0005579)
0.8 3.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.5 4.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.5 2.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.4 7.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.4 1.4 GO:0070722 Tle3-Aes complex(GO:0070722)
0.3 1.8 GO:0097441 basilar dendrite(GO:0097441)
0.2 0.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 2.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 1.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 0.6 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 3.8 GO:0030008 TRAPP complex(GO:0030008)
0.2 1.3 GO:0033269 internode region of axon(GO:0033269)
0.2 3.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.1 GO:0031673 H zone(GO:0031673)
0.1 0.6 GO:0005914 spot adherens junction(GO:0005914)
0.1 1.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 3.7 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.4 GO:0044307 dendritic branch(GO:0044307)
0.1 3.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 0.5 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.1 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 3.2 GO:0035861 site of double-strand break(GO:0035861)
0.1 2.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 2.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 1.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.0 GO:1904602 serotonin-activated cation-selective channel complex(GO:1904602)
0.0 1.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 2.3 GO:0005811 lipid particle(GO:0005811)
0.0 1.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0045095 keratin filament(GO:0045095)
0.0 1.5 GO:0005882 intermediate filament(GO:0005882)
0.0 2.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 2.6 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 28.7 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 25.5 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
4.9 24.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
4.4 13.1 GO:0035730 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
3.7 14.9 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
1.8 80.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.8 3.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.8 4.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.8 2.3 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.7 2.1 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.6 3.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.6 19.5 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.5 2.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.5 1.5 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.5 1.5 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.5 1.4 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.4 1.6 GO:0019862 IgA binding(GO:0019862)
0.4 3.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.4 1.2 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4 2.3 GO:0004985 opioid receptor activity(GO:0004985)
0.4 1.8 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.3 1.0 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.3 1.3 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.3 3.4 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.2 1.0 GO:0070905 serine binding(GO:0070905)
0.2 1.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 2.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.2 1.2 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.2 0.8 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 0.5 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.2 1.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.4 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.1 0.7 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 5.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.6 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.4 GO:0015152 glucose-6-phosphate transmembrane transporter activity(GO:0015152)
0.1 1.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 1.9 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 0.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.9 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 1.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.6 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.6 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 4.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 2.0 GO:0005537 mannose binding(GO:0005537)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.2 GO:0001566 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 4.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.9 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223)
0.1 1.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.8 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.2 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 3.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.5 GO:0019213 deacetylase activity(GO:0019213)
0.1 0.6 GO:0031433 telethonin binding(GO:0031433)
0.1 0.5 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.4 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 2.0 GO:0070888 E-box binding(GO:0070888)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 2.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 3.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 1.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0003680 AT DNA binding(GO:0003680)
0.0 2.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 2.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 4.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 2.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.1 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 2.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.8 GO:0017022 myosin binding(GO:0017022)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 2.4 GO:0030674 protein binding, bridging(GO:0030674)
0.0 2.5 GO:0008083 growth factor activity(GO:0008083)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0000149 SNARE binding(GO:0000149)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 79.9 PID IGF1 PATHWAY IGF1 pathway
0.1 3.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 4.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 3.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 2.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.0 PID ATR PATHWAY ATR signaling pathway
0.0 3.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 3.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 13.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.2 23.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.4 2.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 3.5 REACTOME OPSINS Genes involved in Opsins
0.3 10.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 4.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 5.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 9.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 4.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 3.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.9 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.6 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 6.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.7 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 1.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 3.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 2.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.8 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling