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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Maff

Z-value: 2.60

Motif logo

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Transcription factors associated with Maff

Gene Symbol Gene ID Gene Info
Maff
ENSMUSG00000042622.15 Maff

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Maffmm39_v1_chr15_+_79232137_792322640.821.2e-09Click!

Activity profile of Maff motif

Sorted Z-values of Maff motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Maff

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_-_106126794 17.06 ENSMUST00000082219.6
Chil4
chitinase-like 4
chr19_+_58717319 13.82 ENSMUST00000048644.6
ENSMUST00000236445.2
Pnliprp1
pancreatic lipase related protein 1
chr15_-_78456898 13.71 ENSMUST00000043214.8
Rac2
Rac family small GTPase 2
chr1_-_88133472 11.83 ENSMUST00000119972.4
Dnajb3
DnaJ heat shock protein family (Hsp40) member B3
chr7_-_110462446 11.13 ENSMUST00000033050.5
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr13_-_55677109 9.72 ENSMUST00000223563.2
Dok3
docking protein 3
chr5_+_140491305 9.65 ENSMUST00000043050.9
ENSMUST00000124142.2
Chst12
carbohydrate sulfotransferase 12
chr2_-_69036489 7.66 ENSMUST00000127243.8
ENSMUST00000149643.2
ENSMUST00000167875.9
ENSMUST00000005365.15
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr14_+_30853010 7.60 ENSMUST00000227096.2
Nt5dc2
5'-nucleotidase domain containing 2
chr5_-_67973195 6.84 ENSMUST00000141443.2
Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr7_+_30193047 6.77 ENSMUST00000058280.13
ENSMUST00000133318.8
ENSMUST00000142575.8
ENSMUST00000131040.2
Prodh2
proline dehydrogenase (oxidase) 2
chr5_+_107112186 6.65 ENSMUST00000117196.9
ENSMUST00000031221.12
ENSMUST00000076467.13
Cdc7
cell division cycle 7 (S. cerevisiae)
chr11_-_109364424 6.21 ENSMUST00000070152.12
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr2_-_69036472 6.18 ENSMUST00000112320.8
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chrX_+_92718695 5.91 ENSMUST00000045898.4
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr1_+_135945705 5.72 ENSMUST00000063719.15
Tmem9
transmembrane protein 9
chr2_-_127673738 5.71 ENSMUST00000028858.8
Bub1
BUB1, mitotic checkpoint serine/threonine kinase
chr11_+_67167950 5.51 ENSMUST00000019625.12
Myh8
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr7_-_108769719 5.14 ENSMUST00000208136.2
ENSMUST00000036992.9
Lmo1
LIM domain only 1
chr6_-_40976413 5.09 ENSMUST00000166306.3
Gm2663
predicted gene 2663
chr7_+_44117444 5.09 ENSMUST00000206887.2
ENSMUST00000117324.8
ENSMUST00000120852.8
ENSMUST00000134398.3
ENSMUST00000118628.8
Josd2
Josephin domain containing 2
chr7_+_44117511 4.99 ENSMUST00000121922.3
ENSMUST00000208117.2
Josd2
Josephin domain containing 2
chr1_+_135945798 4.71 ENSMUST00000117950.2
Tmem9
transmembrane protein 9
chr5_+_8106527 4.64 ENSMUST00000148633.4
Sri
sorcin
chr5_+_103902426 4.52 ENSMUST00000153165.8
ENSMUST00000031256.6
Aff1
AF4/FMR2 family, member 1
chr6_+_40941688 4.50 ENSMUST00000076638.7
1810009J06Rik
RIKEN cDNA 1810009J06 gene
chr7_-_100613579 4.29 ENSMUST00000060174.6
P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr8_+_72050292 4.07 ENSMUST00000143662.8
Niban3
niban apoptosis regulator 3
chr8_-_12722099 3.91 ENSMUST00000000776.15
Tubgcp3
tubulin, gamma complex associated protein 3
chr6_+_4003904 3.85 ENSMUST00000031670.10
Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr7_+_44117475 3.74 ENSMUST00000118493.8
Josd2
Josephin domain containing 2
chr3_+_28859585 3.71 ENSMUST00000043867.11
ENSMUST00000194649.2
Rpl22l1
ribosomal protein L22 like 1
chr10_-_88440996 3.61 ENSMUST00000121629.8
Mybpc1
myosin binding protein C, slow-type
chr3_+_127584251 3.60 ENSMUST00000164447.3
Tifa
TRAF-interacting protein with forkhead-associated domain
chr10_-_88440869 3.56 ENSMUST00000119185.8
ENSMUST00000238199.2
Mybpc1
myosin binding protein C, slow-type
chr7_+_30014235 3.55 ENSMUST00000054594.15
ENSMUST00000177078.8
ENSMUST00000176504.8
ENSMUST00000176304.8
Syne4
spectrin repeat containing, nuclear envelope family member 4
chr7_+_44117404 3.48 ENSMUST00000035844.11
Josd2
Josephin domain containing 2
chr10_+_127927443 3.13 ENSMUST00000238829.2
ENSMUST00000217851.2
ENSMUST00000220049.2
Baz2a
bromodomain adjacent to zinc finger domain, 2A
chr3_+_127584449 3.12 ENSMUST00000171621.3
Tifa
TRAF-interacting protein with forkhead-associated domain
chr11_+_75542902 2.88 ENSMUST00000102504.10
Myo1c
myosin IC
chr9_-_57673128 2.79 ENSMUST00000065330.8
Clk3
CDC-like kinase 3
chr19_+_53186430 2.75 ENSMUST00000237099.2
Add3
adducin 3 (gamma)
chr8_-_123302187 2.59 ENSMUST00000213062.2
Aprt
adenine phosphoribosyl transferase
chr17_+_28059129 2.53 ENSMUST00000233657.2
Snrpc
U1 small nuclear ribonucleoprotein C
chr9_+_65368207 2.40 ENSMUST00000034955.8
ENSMUST00000213957.2
Spg21
SPG21, maspardin
chr17_+_28059099 2.40 ENSMUST00000233752.2
Snrpc
U1 small nuclear ribonucleoprotein C
chr15_+_99870661 2.39 ENSMUST00000100206.4
Larp4
La ribonucleoprotein domain family, member 4
chr4_-_139079842 2.26 ENSMUST00000102503.10
Mrto4
mRNA turnover 4, ribosome maturation factor
chr7_-_12771554 2.26 ENSMUST00000125964.8
Ube2m
ubiquitin-conjugating enzyme E2M
chr14_+_119025306 2.21 ENSMUST00000047761.13
ENSMUST00000071546.14
Cldn10
claudin 10
chr11_+_76836545 2.19 ENSMUST00000125145.8
Blmh
bleomycin hydrolase
chr17_+_28059036 2.17 ENSMUST00000071006.9
Snrpc
U1 small nuclear ribonucleoprotein C
chr4_-_109333866 2.11 ENSMUST00000030284.10
Rnf11
ring finger protein 11
chr4_-_136613498 2.01 ENSMUST00000046384.9
C1qb
complement component 1, q subcomponent, beta polypeptide
chr11_+_75542328 1.99 ENSMUST00000069057.13
Myo1c
myosin IC
chr14_+_20979466 1.83 ENSMUST00000022369.9
Vcl
vinculin
chr4_-_139079609 1.76 ENSMUST00000030513.13
ENSMUST00000155257.8
Mrto4
mRNA turnover 4, ribosome maturation factor
chr1_+_75358758 1.73 ENSMUST00000148515.8
ENSMUST00000113590.8
Speg
SPEG complex locus
chr7_+_35148188 1.71 ENSMUST00000118383.8
Slc7a9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr11_-_120520954 1.64 ENSMUST00000106180.2
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr18_-_38471962 1.41 ENSMUST00000139885.2
ENSMUST00000235590.2
ENSMUST00000237487.2
ENSMUST00000063814.15
Gnpda1
glucosamine-6-phosphate deaminase 1
chr17_+_35960600 1.36 ENSMUST00000171166.3
Sfta2
surfactant associated 2
chr7_+_35148461 1.34 ENSMUST00000118969.8
Slc7a9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr11_-_119119287 1.29 ENSMUST00000207655.2
ENSMUST00000036113.4
Tbc1d16
TBC1 domain family, member 16
chr3_+_58322119 1.22 ENSMUST00000099090.7
ENSMUST00000199164.2
Tsc22d2
TSC22 domain family, member 2
chr7_+_35148579 1.11 ENSMUST00000032703.10
Slc7a9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr5_-_35683035 1.06 ENSMUST00000038676.7
Cpz
carboxypeptidase Z
chr1_+_72346572 1.05 ENSMUST00000027379.10
Xrcc5
X-ray repair complementing defective repair in Chinese hamster cells 5
chr16_+_72460029 1.00 ENSMUST00000023600.8
Robo1
roundabout guidance receptor 1
chr11_+_74721733 0.97 ENSMUST00000000291.9
Mnt
max binding protein
chr18_+_13107535 0.90 ENSMUST00000234035.2
ENSMUST00000235053.2
Impact
impact, RWD domain protein
chr12_-_16696958 0.89 ENSMUST00000238839.2
Lpin1
lipin 1
chr15_+_99870787 0.88 ENSMUST00000231160.2
Larp4
La ribonucleoprotein domain family, member 4
chr3_+_109481223 0.86 ENSMUST00000106576.3
Vav3
vav 3 oncogene
chr17_+_71511642 0.84 ENSMUST00000126681.8
Lpin2
lipin 2
chr10_-_121462219 0.81 ENSMUST00000039810.8
ENSMUST00000218004.2
Xpot
exportin, tRNA (nuclear export receptor for tRNAs)
chr14_-_36857202 0.75 ENSMUST00000165649.4
ENSMUST00000224769.2
Ghitm
growth hormone inducible transmembrane protein
chr11_+_76836330 0.74 ENSMUST00000021197.10
Blmh
bleomycin hydrolase
chr12_+_16944896 0.73 ENSMUST00000020904.8
Rock2
Rho-associated coiled-coil containing protein kinase 2
chr11_-_69471056 0.72 ENSMUST00000132548.2
Wrap53
WD repeat containing, antisense to Trp53
chr2_-_130239434 0.71 ENSMUST00000028897.8
Cpxm1
carboxypeptidase X 1 (M14 family)
chr19_-_8906686 0.60 ENSMUST00000096242.5
Rom1
rod outer segment membrane protein 1
chr14_-_36857083 0.59 ENSMUST00000042564.17
Ghitm
growth hormone inducible transmembrane protein
chr7_-_4687916 0.55 ENSMUST00000206306.2
ENSMUST00000205952.2
ENSMUST00000079970.6
Hspbp1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr16_-_16377982 0.50 ENSMUST00000161861.8
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr10_+_101517348 0.48 ENSMUST00000179929.8
ENSMUST00000219195.2
ENSMUST00000127504.9
Mgat4c
MGAT4 family, member C
chr8_-_84420633 0.47 ENSMUST00000144258.8
Pkn1
protein kinase N1
chr6_+_30401864 0.46 ENSMUST00000068240.13
ENSMUST00000068259.10
ENSMUST00000132581.8
Klhdc10
kelch domain containing 10
chr14_+_15369152 0.38 ENSMUST00000167923.8
Gm3696
predicted gene 3696
chr18_-_39652468 0.35 ENSMUST00000237944.2
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr9_+_45749869 0.35 ENSMUST00000078111.11
ENSMUST00000034591.11
Bace1
beta-site APP cleaving enzyme 1
chr19_-_11301919 0.34 ENSMUST00000159269.2
Ms4a7
membrane-spanning 4-domains, subfamily A, member 7
chr6_+_83771953 0.29 ENSMUST00000037376.14
Nagk
N-acetylglucosamine kinase
chr6_+_120750510 0.29 ENSMUST00000112682.4
Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr12_+_104229376 0.25 ENSMUST00000109958.3
Serpina3i
serine (or cysteine) peptidase inhibitor, clade A, member 3I
chr2_-_20948230 0.18 ENSMUST00000140230.2
Arhgap21
Rho GTPase activating protein 21
chr15_+_99870714 0.17 ENSMUST00000230956.2
Larp4
La ribonucleoprotein domain family, member 4
chr11_+_81992662 0.12 ENSMUST00000000194.4
Ccl12
chemokine (C-C motif) ligand 12
chr8_+_124138163 0.10 ENSMUST00000071134.4
ENSMUST00000212743.2
Tubb3
tubulin, beta 3 class III
chr16_+_96295011 0.02 ENSMUST00000233816.2
Pcp4
Purkinje cell protein 4
chr14_-_44239726 0.00 ENSMUST00000096869.3
Ang6
angiogenin, ribonuclease A family, member 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
2.3 6.8 GO:0010133 proline catabolic process to glutamate(GO:0010133)
1.9 17.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.4 13.7 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
1.1 5.7 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
1.1 6.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
1.0 4.2 GO:0015811 L-cystine transport(GO:0015811)
0.8 7.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.8 6.8 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.7 5.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.7 2.9 GO:0043418 homocysteine catabolic process(GO:0043418)
0.7 1.4 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.6 2.6 GO:0046084 adenine salvage(GO:0006168) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.6 4.9 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.6 11.1 GO:0006026 aminoglycan catabolic process(GO:0006026) glycosaminoglycan catabolic process(GO:0006027)
0.5 4.6 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.5 4.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.4 7.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 1.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.3 3.9 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3 3.5 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3 0.9 GO:1901561 cellular response to benomyl(GO:0072755) response to benomyl(GO:1901561)
0.3 3.1 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.3 1.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.3 5.5 GO:0030049 muscle filament sliding(GO:0030049)
0.2 0.8 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.7 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 4.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 17.3 GO:0016579 protein deubiquitination(GO:0016579)
0.1 13.4 GO:0007052 mitotic spindle organization(GO:0007052)
0.1 0.7 GO:0090666 telomere assembly(GO:0032202) scaRNA localization to Cajal body(GO:0090666)
0.1 1.8 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 2.3 GO:0045116 protein neddylation(GO:0045116)
0.1 5.9 GO:0001541 ovarian follicle development(GO:0001541)
0.1 0.9 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.5 GO:0030035 microspike assembly(GO:0030035)
0.1 0.5 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.4 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 3.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.6 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 6.2 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.9 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 3.4 GO:0045727 positive regulation of translation(GO:0045727)
0.0 2.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 1.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 7.6 GO:0016311 dephosphorylation(GO:0016311)
0.0 2.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.2 GO:0006970 response to osmotic stress(GO:0006970)
0.0 1.4 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 3.5 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 1.0 GO:0007569 cell aging(GO:0007569)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 13.8 GO:0031262 Ndc80 complex(GO:0031262)
1.9 5.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.2 4.6 GO:0042584 chromaffin granule membrane(GO:0042584)
1.0 3.9 GO:0008275 gamma-tubulin small complex(GO:0008275)
1.0 4.9 GO:0045160 myosin I complex(GO:0045160)
0.5 3.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.5 7.1 GO:0000243 commitment complex(GO:0000243)
0.5 5.5 GO:0032982 myosin filament(GO:0032982)
0.3 7.2 GO:0005859 muscle myosin complex(GO:0005859)
0.2 1.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 3.5 GO:0044453 nuclear membrane part(GO:0044453)
0.1 6.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.8 GO:0005916 fascia adherens(GO:0005916)
0.1 4.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 11.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 13.7 GO:0005884 actin filament(GO:0005884)
0.1 2.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 3.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 10.8 GO:0005770 late endosome(GO:0005770)
0.0 4.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 6.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.0 GO:0030673 axolemma(GO:0030673)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 2.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 2.7 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 4.3 GO:0016324 apical plasma membrane(GO:0016324)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
1.9 17.1 GO:0004568 chitinase activity(GO:0004568)
1.8 7.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
1.5 5.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
1.1 4.3 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
1.0 4.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.9 2.6 GO:0003999 adenine binding(GO:0002055) adenine phosphoribosyltransferase activity(GO:0003999)
0.8 2.3 GO:0018169 ribosomal S6-glutamic acid ligase activity(GO:0018169)
0.7 13.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.5 1.4 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.4 11.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 7.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.3 10.4 GO:0000146 microfilament motor activity(GO:0000146)
0.3 7.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 3.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 6.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 2.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 3.1 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.2 6.8 GO:0071949 FAD binding(GO:0071949)
0.2 17.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 4.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 9.7 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 1.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 3.4 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.3 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 6.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.4 GO:0038051 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 2.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 11.8 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 9.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.7 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 2.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 3.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 8.2 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 13.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 2.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 5.7 PID AURORA B PATHWAY Aurora B signaling
0.1 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 2.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 3.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 11.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 9.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.4 14.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.3 2.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 7.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 3.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 12.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 3.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 19.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 6.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 6.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 4.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.8 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 1.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 4.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation