Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Mga

Z-value: 1.61

Motif logo

Transcription factors associated with Mga

Gene Symbol Gene ID Gene Info
ENSMUSG00000033943.16 Mga

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mgamm39_v1_chr2_+_119727689_1197277860.438.3e-03Click!

Activity profile of Mga motif

Sorted Z-values of Mga motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Mga

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr14_-_56339915 15.28 ENSMUST00000015583.2
cathepsin G
chr5_+_149202157 6.22 ENSMUST00000200806.4
arachidonate 5-lipoxygenase activating protein
chr17_+_36172210 4.86 ENSMUST00000074259.15
ENSMUST00000174873.2
nurim (nuclear envelope membrane protein)
chr14_+_66043281 4.41 ENSMUST00000022612.10
PDZ binding kinase
chr5_-_120915693 4.18 ENSMUST00000044833.9
2'-5' oligoadenylate synthetase 3
chr11_-_120930193 4.17 ENSMUST00000026159.6
CD7 antigen
chr15_-_66673425 4.02 ENSMUST00000168589.8
src-like adaptor
chr2_+_84966569 3.54 ENSMUST00000057019.9
apelin receptor
chr11_+_116422712 3.31 ENSMUST00000100201.10
sphingosine kinase 1
chr6_+_123206802 3.16 ENSMUST00000112554.9
ENSMUST00000024118.11
ENSMUST00000117130.8
C-type lectin domain family 4, member n
chr8_-_34578880 3.16 ENSMUST00000080152.5
predicted pseudogene 10131
chr19_-_40576817 2.91 ENSMUST00000175932.2
ENSMUST00000176955.8
ENSMUST00000149476.3
aldehyde dehydrogenase 18 family, member A1
chr7_-_30579686 2.88 ENSMUST00000188157.7
ENSMUST00000190753.2
ENSMUST00000186154.7
ENSMUST00000190617.7
CD22 antigen
chr16_+_90182895 2.87 ENSMUST00000065856.8
hormonally upregulated Neu-associated kinase
chr12_+_111387023 2.86 ENSMUST00000220852.2
exocyst complex component 3-like 4
chr12_-_114252202 2.81 ENSMUST00000195124.6
ENSMUST00000103481.3
immunoglobulin heavy variable 3-6
chr5_+_137744228 2.40 ENSMUST00000100539.10
TSC22 domain family, member 4
chr19_+_53298906 2.30 ENSMUST00000003870.15
MAX interactor 1, dimerization protein
chr4_-_41314877 2.26 ENSMUST00000030145.9
DDB1 and CUL4 associated factor 12
chr6_+_129374441 2.20 ENSMUST00000112081.9
ENSMUST00000112079.3
C-type lectin domain family 1, member b
chr6_-_56900709 2.20 ENSMUST00000205087.2
5'-nucleotidase, cytosolic III
chr8_-_84831391 2.15 ENSMUST00000041367.9
ENSMUST00000210279.2
DDB1 and CUL4 associated factor 15
chrX_+_20483742 2.13 ENSMUST00000115375.8
ENSMUST00000115374.8
ENSMUST00000084383.10
RNA binding motif protein 10
chr6_+_129374260 2.06 ENSMUST00000032262.14
C-type lectin domain family 1, member b
chrX_+_161684735 1.91 ENSMUST00000112302.8
ENSMUST00000112301.8
cytidine 5'-triphosphate synthase 2
chr17_-_32569480 1.77 ENSMUST00000235265.2
ENSMUST00000236503.2
ENSMUST00000050214.9
A kinase (PRKA) anchor protein 8-like
chr19_+_47217279 1.73 ENSMUST00000111807.5
neuralized E3 ubiquitin protein ligase 1A
chr7_+_27186335 1.71 ENSMUST00000008528.8
SERTA domain containing 1
chr4_-_116982804 1.68 ENSMUST00000183310.2
BTB (POZ) domain containing 19
chr17_+_23898223 1.66 ENSMUST00000024699.4
ENSMUST00000232719.2
claudin 6
chr6_+_67838100 1.49 ENSMUST00000200586.2
ENSMUST00000103309.3
immunoglobulin kappa variable 17-127
chr6_-_69835868 1.46 ENSMUST00000103369.2
immunoglobulin kappa chain variable 12-41
chr2_-_129213050 1.44 ENSMUST00000028881.14
interleukin 1 beta
chrX_+_35152460 1.42 ENSMUST00000033419.13
dedicator of cytokinesis 11
chr11_+_116421923 1.34 ENSMUST00000138840.8
sphingosine kinase 1
chr9_+_59198829 1.28 ENSMUST00000217570.2
ENSMUST00000026266.9
ADP-dependent glucokinase
chr15_+_54274151 1.19 ENSMUST00000036737.4
collectin sub-family member 10
chr4_+_132291369 1.19 ENSMUST00000070690.8
platelet-activating factor receptor
chr19_+_54033681 1.11 ENSMUST00000237285.2
adrenergic receptor, alpha 2a
chr15_+_51740825 1.10 ENSMUST00000137116.3
ENSMUST00000161651.2
ENSMUST00000059599.10
UTP23 small subunit processome component
chr6_-_148797648 1.02 ENSMUST00000072324.12
ENSMUST00000111569.9
caprin family member 2
chr6_+_68414401 1.01 ENSMUST00000103324.3
immunoglobulin kappa chain variable 15-103
chr10_+_75047897 0.98 ENSMUST00000218766.2
sperm antigen with calponin homology and coiled-coil domains 1-like
chr4_-_62443273 0.96 ENSMUST00000030091.10
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr9_-_96993169 0.92 ENSMUST00000085206.11
solute carrier family 25, member 36
chr6_+_5390386 0.90 ENSMUST00000183358.2
ankyrin repeat and SOCS box-containing 4
chr2_+_151414524 0.88 ENSMUST00000028950.9
syndecan binding protein (syntenin) 2
chr8_+_83891972 0.83 ENSMUST00000034145.11
TBC1 domain family, member 9
chr1_-_130390418 0.78 ENSMUST00000027650.13
CD55 molecule, decay accelerating factor for complement
chr9_-_96360676 0.75 ENSMUST00000057500.6
ring finger protein 7
chr17_-_8046125 0.74 ENSMUST00000239425.2
ENSMUST00000167580.8
fibronectin type III domain containing 1
chr8_+_123338357 0.72 ENSMUST00000015157.10
trafficking protein particle complex 2-like
chr7_-_3828640 0.67 ENSMUST00000189095.7
ENSMUST00000094911.5
ENSMUST00000153846.8
ENSMUST00000108619.8
ENSMUST00000108620.8
predicted gene 15448
chr17_+_23898633 0.67 ENSMUST00000233364.2
claudin 6
chr3_+_105778174 0.63 ENSMUST00000164730.2
ENSMUST00000010279.10
adenosine A3 receptor
transmembrane and immunoglobulin domain containing 3
chr3_+_87283687 0.63 ENSMUST00000163661.8
ENSMUST00000072480.9
Fc receptor-like 1
chr3_+_75982890 0.60 ENSMUST00000160261.8
follistatin-like 5
chr3_-_146227144 0.57 ENSMUST00000199079.2
ENSMUST00000029838.11
ribosome production factor 1 homolog
chr11_+_113548201 0.56 ENSMUST00000148736.8
ENSMUST00000142069.8
ENSMUST00000134418.8
component of oligomeric golgi complex 1
chr17_+_21031817 0.54 ENSMUST00000232810.2
ENSMUST00000233712.2
ENSMUST00000232852.2
vomeronasal 1 receptor 229
chr2_-_111400026 0.51 ENSMUST00000217772.2
ENSMUST00000207283.3
olfactory receptor 1295
chr16_-_35951553 0.49 ENSMUST00000161638.2
ENSMUST00000096090.3
cystatin A1
chr19_-_5660057 0.48 ENSMUST00000236229.2
ENSMUST00000235701.2
ENSMUST00000236264.2
K(lysine) acetyltransferase 5
chr14_-_60414932 0.44 ENSMUST00000140924.3
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr9_-_109278192 0.44 ENSMUST00000084984.8
F-box and WD-40 domain protein 16
chr19_+_46064302 0.41 ENSMUST00000165017.2
ENSMUST00000223741.2
ENSMUST00000225780.2
nucleolar and coiled-body phosphoprotein 1
chr14_+_3576275 0.41 ENSMUST00000151926.8
ubiquitin-conjugating enzyme E2E 2
chr15_+_51741138 0.40 ENSMUST00000136129.2
UTP23 small subunit processome component
chr6_+_70699533 0.40 ENSMUST00000103405.2
immunoglobulin kappa joining 1
chr7_+_48438751 0.38 ENSMUST00000118927.8
ENSMUST00000125280.8
zinc finger, DHHC domain containing 13
chr9_-_96360648 0.33 ENSMUST00000071301.5
ring finger protein 7
chr12_+_84363603 0.26 ENSMUST00000045931.12
zinc finger protein 410
chr1_+_52047368 0.26 ENSMUST00000027277.7
signal transducer and activator of transcription 4
chr6_-_41613322 0.25 ENSMUST00000031902.7
transient receptor potential cation channel, subfamily V, member 6
chr9_-_109531768 0.25 ENSMUST00000098359.4
F-box and WD-40 domain protein 18
chr6_-_68857658 0.24 ENSMUST00000198756.2
predicted gene 42543
chr9_-_109575157 0.22 ENSMUST00000071917.4
F-box and WD-40 domain protein 26
chr4_-_132459762 0.22 ENSMUST00000045550.5
X-linked Kx blood group related 8
chr12_-_54742597 0.19 ENSMUST00000110713.10
ENSMUST00000162106.8
ENSMUST00000160085.2
ENSMUST00000161592.8
ENSMUST00000163433.8
ENSMUST00000067272.9
E2F-associated phosphoprotein
chr3_+_87283767 0.14 ENSMUST00000194786.6
ENSMUST00000191666.2
Fc receptor-like 1
chr2_-_88768449 0.12 ENSMUST00000215205.2
ENSMUST00000213412.2
olfactory receptor 1211
chr7_-_10292412 0.12 ENSMUST00000236246.2
vomeronasal 1 receptor 68
chr9_-_117081518 0.11 ENSMUST00000111773.10
ENSMUST00000068962.14
ENSMUST00000044901.14
RNA binding motif, single stranded interacting protein
chr5_-_124490296 0.10 ENSMUST00000111472.6
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr6_+_67873135 0.07 ENSMUST00000103310.3
immunoglobulin kappa variable 14-126
chr2_+_83474779 0.06 ENSMUST00000081591.7
zinc finger CCCH-type containing 15
chr9_-_109397316 0.06 ENSMUST00000198112.2
ENSMUST00000198397.5
ENSMUST00000056745.12
F-box and WD-40 domain protein 15
chr9_-_85631361 0.03 ENSMUST00000039213.15
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr19_+_38043506 0.02 ENSMUST00000237408.2
centrosomal protein 55
chr19_+_13628455 0.02 ENSMUST00000213900.2
olfactory receptor 1490
chr2_+_3337194 0.01 ENSMUST00000115089.2
ENSMUST00000228935.2
acyl-Coenzyme A binding domain containing 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 15.3 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
1.0 6.2 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
1.0 2.9 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.9 3.5 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.7 4.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.5 4.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.5 1.4 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.3 1.5 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.3 1.2 GO:1902941 regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
0.2 2.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.8 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.2 0.8 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.2 0.9 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.2 2.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.2 2.9 GO:0051601 exocyst localization(GO:0051601)
0.2 1.1 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 1.9 GO:0046036 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.1 1.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 2.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 3.2 GO:0050832 defense response to fungus(GO:0050832)
0.1 1.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 4.3 GO:0030220 platelet formation(GO:0030220)
0.1 0.9 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 4.2 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 0.6 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 4.4 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 1.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.4 GO:0003011 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 4.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.4 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.7 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 1.0 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 1.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 2.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.5 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.3 GO:0006096 glycolytic process(GO:0006096)
0.0 1.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.2 GO:1904888 cranial skeletal system development(GO:1904888)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 4.9 GO:0005652 nuclear lamina(GO:0005652)
0.2 1.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 15.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 2.9 GO:0000145 exocyst(GO:0000145)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.7 GO:0097440 apical dendrite(GO:0097440)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 2.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 6.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 3.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 1.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.2 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
1.0 2.9 GO:0004350 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.5 4.6 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.5 1.9 GO:0003883 CTP synthase activity(GO:0003883)
0.4 1.7 GO:0045183 translation factor activity, non-nucleic acid binding(GO:0045183)
0.3 4.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 1.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 1.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 2.9 GO:0015026 coreceptor activity(GO:0015026)
0.1 1.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 2.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 2.4 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 15.3 GO:0008201 heparin binding(GO:0008201)
0.1 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 4.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.8 GO:0005521 lamin binding(GO:0005521)
0.1 1.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.9 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 2.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 6.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0043274 phospholipase binding(GO:0043274)
0.0 2.9 GO:0000149 SNARE binding(GO:0000149)
0.0 1.5 GO:0003823 antigen binding(GO:0003823)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 15.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 4.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 1.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 4.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 2.9 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 5.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 4.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 15.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 4.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 5.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 2.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 1.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 3.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors