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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nfat5

Z-value: 0.54

Motif logo

Transcription factors associated with Nfat5

Gene Symbol Gene ID Gene Info
ENSMUSG00000003847.17 Nfat5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfat5mm39_v1_chr8_+_108020092_1080201180.372.6e-02Click!

Activity profile of Nfat5 motif

Sorted Z-values of Nfat5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfat5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_99383938 1.83 ENSMUST00000006969.8
keratin 23
chr1_+_87983099 1.75 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr3_-_98631847 1.70 ENSMUST00000107021.8
ENSMUST00000107022.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr10_-_95251327 1.58 ENSMUST00000172070.8
ENSMUST00000150432.8
suppressor of cytokine signaling 2
chr1_+_87983189 1.48 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr10_-_95251145 1.41 ENSMUST00000119917.2
suppressor of cytokine signaling 2
chr5_-_104169696 1.28 ENSMUST00000119025.2
hydroxysteroid (17-beta) dehydrogenase 11
chr5_-_104169785 1.24 ENSMUST00000031251.16
hydroxysteroid (17-beta) dehydrogenase 11
chr1_+_24717711 1.04 ENSMUST00000191471.7
LMBR1 domain containing 1
chr4_-_49506538 1.04 ENSMUST00000043056.9
bile acid-Coenzyme A: amino acid N-acyltransferase
chr10_-_78187524 1.03 ENSMUST00000166360.8
1-acylglycerol-3-phosphate O-acyltransferase 3
chr10_-_78187887 1.03 ENSMUST00000105388.8
1-acylglycerol-3-phosphate O-acyltransferase 3
chr1_+_24717722 1.01 ENSMUST00000186096.7
LMBR1 domain containing 1
chr6_+_91661074 1.00 ENSMUST00000205480.2
ENSMUST00000206545.2
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr10_-_78188046 0.98 ENSMUST00000146899.2
1-acylglycerol-3-phosphate O-acyltransferase 3
chr10_-_78187545 0.94 ENSMUST00000105390.8
1-acylglycerol-3-phosphate O-acyltransferase 3
chr1_-_93373145 0.92 ENSMUST00000186787.7
high density lipoprotein (HDL) binding protein
chr1_+_24717793 0.92 ENSMUST00000186190.2
LMBR1 domain containing 1
chr10_-_125164399 0.90 ENSMUST00000063318.10
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr11_-_88754543 0.81 ENSMUST00000107904.3
A kinase (PRKA) anchor protein 1
chr6_+_91661034 0.75 ENSMUST00000032185.9
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr10_+_21870565 0.73 ENSMUST00000020145.12
serum/glucocorticoid regulated kinase 1
chr5_+_120649233 0.71 ENSMUST00000068326.14
ENSMUST00000111890.9
ENSMUST00000076051.12
ENSMUST00000147496.2
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr2_+_67948057 0.71 ENSMUST00000112346.3
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr15_+_25933632 0.68 ENSMUST00000228327.2
reticulophagy regulator 1
chr14_+_5894220 0.66 ENSMUST00000063750.8
retinoic acid receptor, beta
chr19_+_25214322 0.62 ENSMUST00000049400.15
KN motif and ankyrin repeat domains 1
chr11_+_120382666 0.58 ENSMUST00000026899.4
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr7_-_80052491 0.56 ENSMUST00000122232.8
furin (paired basic amino acid cleaving enzyme)
chr2_-_177567397 0.53 ENSMUST00000108934.9
ENSMUST00000081529.11
zinc finger protein 972
chrX_-_153999440 0.52 ENSMUST00000026318.15
spermidine/spermine N1-acetyl transferase 1
chr2_-_30305313 0.50 ENSMUST00000132981.9
ENSMUST00000129494.2
carnitine acetyltransferase
chr18_+_36693646 0.47 ENSMUST00000155329.9
ankyrin repeat and KH domain containing 1
chr10_+_21869776 0.44 ENSMUST00000092673.11
serum/glucocorticoid regulated kinase 1
chr10_-_29411857 0.44 ENSMUST00000092623.5
R-spondin 3
chrX_-_153999333 0.43 ENSMUST00000112551.4
spermidine/spermine N1-acetyl transferase 1
chr18_+_36693024 0.43 ENSMUST00000134146.8
ankyrin repeat and KH domain containing 1
chr3_-_27764571 0.42 ENSMUST00000046157.10
fibronectin type III domain containing 3B
chr4_+_19575128 0.40 ENSMUST00000108253.8
ENSMUST00000029888.4
regulator of microtubule dynamics 1
chr3_-_27764522 0.39 ENSMUST00000195008.6
fibronectin type III domain containing 3B
chr7_-_141472218 0.39 ENSMUST00000151890.3
toll interacting protein
chr11_-_118292678 0.39 ENSMUST00000106290.4
lectin, galactoside-binding, soluble, 3 binding protein
chr14_-_4808744 0.38 ENSMUST00000022303.17
ENSMUST00000091471.12
thyroid hormone receptor beta
chr15_+_99476935 0.36 ENSMUST00000023752.6
aquaporin 2
chr15_-_75766321 0.36 ENSMUST00000023237.8
nicotinate phosphoribosyltransferase
chr12_-_83643964 0.35 ENSMUST00000048319.6
zinc finger, FYVE domain containing 1
chr9_+_92339422 0.34 ENSMUST00000034941.9
phospholipid scramblase 4
chr16_+_84571011 0.34 ENSMUST00000114195.8
junction adhesion molecule 2
chrX_+_138585728 0.33 ENSMUST00000096313.4
TBC1 domain family, member 8B
chrX_-_16683578 0.33 ENSMUST00000040820.13
monoamine oxidase B
chr6_+_73225616 0.32 ENSMUST00000203632.2
succinate-CoA ligase, GDP-forming, alpha subunit
chr12_-_83643883 0.31 ENSMUST00000221919.2
zinc finger, FYVE domain containing 1
chr10_+_4561974 0.30 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chr7_-_30298287 0.30 ENSMUST00000108150.2
zinc finger and BTB domain containing 32
chr4_-_82423985 0.29 ENSMUST00000107245.9
ENSMUST00000107246.2
nuclear factor I/B
chr2_-_30305472 0.28 ENSMUST00000134120.2
ENSMUST00000102854.10
carnitine acetyltransferase
chr11_+_118913788 0.26 ENSMUST00000026662.8
chromobox 2
chr6_-_101354858 0.26 ENSMUST00000075994.11
PDZ domain containing RING finger 3
chr11_-_118292758 0.25 ENSMUST00000043722.10
lectin, galactoside-binding, soluble, 3 binding protein
chr6_-_144155197 0.24 ENSMUST00000038815.14
ENSMUST00000111749.8
ENSMUST00000170367.9
SRY (sex determining region Y)-box 5
chr12_+_98886826 0.24 ENSMUST00000085109.10
ENSMUST00000079146.13
tetratricopeptide repeat domain 8
chr10_+_84458143 0.24 ENSMUST00000077175.7
polymerase (RNA) III (DNA directed) polypeptide B
chr4_-_82423944 0.23 ENSMUST00000107248.8
ENSMUST00000107247.8
nuclear factor I/B
chr15_-_38079089 0.23 ENSMUST00000110336.4
ubiquitin protein ligase E3 component n-recognin 5
chr19_-_10502468 0.22 ENSMUST00000025570.8
ENSMUST00000236455.2
succinate dehydrogenase complex assembly factor 2
chr19_+_56414114 0.20 ENSMUST00000238892.2
caspase 7
chr1_+_88334678 0.20 ENSMUST00000027518.12
secreted phosphoprotein 2
chr7_-_97066937 0.19 ENSMUST00000043077.8
thyroid hormone responsive
chr1_+_192984278 0.19 ENSMUST00000016315.16
laminin, beta 3
chr11_+_83741657 0.19 ENSMUST00000021016.10
HNF1 homeobox B
chr19_+_10502612 0.13 ENSMUST00000237321.2
ENSMUST00000038379.5
cleavage and polyadenylation specific factor 7
chr11_+_83741689 0.13 ENSMUST00000108114.9
HNF1 homeobox B
chr5_-_66775979 0.13 ENSMUST00000162382.8
ENSMUST00000159786.8
ENSMUST00000162349.8
ENSMUST00000087256.12
ENSMUST00000160103.8
ENSMUST00000160870.8
amyloid beta (A4) precursor protein-binding, family B, member 2
chr7_-_126224848 0.11 ENSMUST00000032961.4
nuclear protein transcription regulator 1
chr19_-_10502546 0.11 ENSMUST00000237827.2
succinate dehydrogenase complex assembly factor 2
chr9_-_105398346 0.10 ENSMUST00000176770.8
ENSMUST00000085133.13
ATPase, Ca++-sequestering
chr16_+_27208660 0.10 ENSMUST00000143823.2
coiled-coil domain containing 50
chr14_-_78866714 0.10 ENSMUST00000228362.2
ENSMUST00000227767.2
diacylglycerol kinase, eta
chr2_-_30305401 0.09 ENSMUST00000142096.2
carnitine acetyltransferase
chr9_+_7764042 0.09 ENSMUST00000052865.16
transmembrane protein 123
chr5_-_69749617 0.09 ENSMUST00000173927.8
ENSMUST00000120789.8
ENSMUST00000031117.13
glucosamine-6-phosphate deaminase 2
chr19_+_10502679 0.07 ENSMUST00000235674.2
cleavage and polyadenylation specific factor 7
chr8_+_126456710 0.07 ENSMUST00000143504.8
nucleoside-triphosphatase, cancer-related
chr8_-_70426910 0.07 ENSMUST00000116463.4
GATA zinc finger domain containing 2A
chr16_+_84571249 0.06 ENSMUST00000098407.3
junction adhesion molecule 2
chr6_-_144155167 0.06 ENSMUST00000077160.12
SRY (sex determining region Y)-box 5
chr1_+_165312738 0.05 ENSMUST00000111440.8
ENSMUST00000027852.15
ENSMUST00000111439.8
adenylate cyclase 10
chr6_+_67701864 0.03 ENSMUST00000103304.3
immunoglobulin kappa variable 1-133
chr2_-_11506511 0.03 ENSMUST00000183869.8
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr18_-_78640066 0.03 ENSMUST00000235389.2
ENSMUST00000237674.2
solute carrier family 14 (urea transporter), member 2
chrX_-_17437801 0.03 ENSMUST00000177213.8
FUN14 domain containing 1
chr2_-_90054837 0.02 ENSMUST00000213994.3
olfactory receptor 1506
chr8_-_25581354 0.02 ENSMUST00000125466.2
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chrX_+_37861548 0.02 ENSMUST00000050744.6
RIKEN cDNA 6030498E09 gene
chr14_+_59716265 0.02 ENSMUST00000224893.2
calcium binding protein 39-like
chr7_+_140658101 0.01 ENSMUST00000106039.9
plakophilin 3
chr18_+_61408073 0.01 ENSMUST00000135688.2
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr7_+_108549545 0.01 ENSMUST00000207583.2
tubby bipartite transcription factor
chr11_+_97206542 0.01 ENSMUST00000019026.10
ENSMUST00000132168.2
mitochondrial ribosomal protein L45
chr13_+_23343482 0.01 ENSMUST00000226845.2
ENSMUST00000228666.2
ENSMUST00000227388.2
vomeronasal 1 receptor 219
chr9_-_29874401 0.00 ENSMUST00000075069.11
neurotrimin

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:0038016 insulin receptor internalization(GO:0038016)
0.6 2.5 GO:0006710 androgen catabolic process(GO:0006710)
0.6 1.8 GO:0015734 beta-alanine transport(GO:0001762) taurine transport(GO:0015734)
0.3 3.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.6 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 1.0 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.6 GO:0015744 succinate transport(GO:0015744)
0.1 0.6 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.0 GO:0019530 taurine metabolic process(GO:0019530)
0.1 0.9 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.9 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.4 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.8 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 3.0 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.3 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.7 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.3 GO:0061228 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.1 0.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.7 GO:0061709 reticulophagy(GO:0061709)
0.1 1.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.3 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 0.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.2 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.1 0.8 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.1 0.3 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.3 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.7 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.4 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.1 GO:0032468 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.0 3.6 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.4 GO:0036010 protein localization to endosome(GO:0036010)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.5 GO:0030061 mitochondrial crista(GO:0030061)
0.1 3.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.4 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 2.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 1.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0005368 beta-alanine transmembrane transporter activity(GO:0001761) taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
0.5 3.0 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 3.0 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 1.0 GO:0019809 spermidine binding(GO:0019809)
0.2 0.9 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.2 0.6 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.2 0.7 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.2 0.7 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 4.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 2.5 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 1.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.4 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.3 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 3.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.4 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.8 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 1.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.4 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.6 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.0 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 4.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)