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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nfix

Z-value: 1.51

Motif logo

Transcription factors associated with Nfix

Gene Symbol Gene ID Gene Info
ENSMUSG00000001911.17 Nfix

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfixmm39_v1_chr8_-_85500998_855011080.572.7e-04Click!

Activity profile of Nfix motif

Sorted Z-values of Nfix motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfix

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_97066937 8.15 ENSMUST00000043077.8
thyroid hormone responsive
chr7_+_140343652 5.83 ENSMUST00000026552.9
ENSMUST00000209253.2
ENSMUST00000210235.2
cytochrome P450, family 2, subfamily e, polypeptide 1
chr7_+_130633776 5.59 ENSMUST00000084509.7
ENSMUST00000213064.3
ENSMUST00000208311.4
deleted in malignant brain tumors 1
chr7_-_126651847 5.26 ENSMUST00000205424.2
zymogen granule protein 16
chr5_+_115604321 5.09 ENSMUST00000145785.8
ENSMUST00000031495.11
ENSMUST00000112071.8
ENSMUST00000125568.2
phospholipase A2, group IB, pancreas
chr8_-_93857899 4.87 ENSMUST00000034189.17
carboxylesterase 1C
chr6_-_141801897 4.63 ENSMUST00000165990.8
solute carrier organic anion transporter family, member 1a4
chr6_-_141801918 4.23 ENSMUST00000163678.2
solute carrier organic anion transporter family, member 1a4
chr19_-_43512929 2.68 ENSMUST00000026196.14
glutamic-oxaloacetic transaminase 1, soluble
chr19_-_46661321 2.49 ENSMUST00000026012.8
cytochrome P450, family 17, subfamily a, polypeptide 1
chr9_-_103099262 2.40 ENSMUST00000170904.2
transferrin
chr5_-_77262968 2.39 ENSMUST00000081964.7
HOP homeobox
chr19_-_46661501 2.33 ENSMUST00000236174.2
cytochrome P450, family 17, subfamily a, polypeptide 1
chr17_-_74257164 2.26 ENSMUST00000024866.6
xanthine dehydrogenase
chr19_-_40175709 2.20 ENSMUST00000051846.13
cytochrome P450, family 2, subfamily c, polypeptide 70
chr5_+_90608751 2.20 ENSMUST00000031314.10
albumin
chr6_-_78355834 2.14 ENSMUST00000089667.8
ENSMUST00000167492.4
regenerating islet-derived 3 delta
chr10_+_57660948 2.13 ENSMUST00000020024.12
fatty acid binding protein 7, brain
chr3_-_129126362 2.11 ENSMUST00000029658.14
glutamyl aminopeptidase
chr1_+_87998487 2.09 ENSMUST00000073772.5
UDP glucuronosyltransferase 1 family, polypeptide A9
chr6_-_136852792 1.93 ENSMUST00000032342.3
matrix Gla protein
chr3_+_62245765 1.73 ENSMUST00000079300.13
Rho guanine nucleotide exchange factor (GEF) 26
chr2_+_121978156 1.68 ENSMUST00000102476.5
beta-2 microglobulin
chr1_+_133292898 1.65 ENSMUST00000129213.2
ethanolamine kinase 2
chr1_-_162687369 1.64 ENSMUST00000193078.6
flavin containing monooxygenase 1
chr5_-_87054796 1.60 ENSMUST00000031181.16
ENSMUST00000113333.2
UDP glucuronosyltransferase 2 family, polypeptide B34
chr11_+_101258368 1.52 ENSMUST00000019469.3
glucose-6-phosphatase, catalytic
chr5_-_137919873 1.51 ENSMUST00000031741.8
cytochrome P450, family 3, subfamily a, polypeptide 13
chr17_-_35081129 1.48 ENSMUST00000154526.8
complement factor B
chr17_-_35081456 1.47 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr7_-_48497771 1.46 ENSMUST00000032658.14
cysteine and glycine-rich protein 3
chr11_-_100012384 1.39 ENSMUST00000007275.3
keratin 13
chr1_+_133109059 1.34 ENSMUST00000187285.7
pleckstrin homology domain containing, family A member 6
chr10_+_116111441 1.28 ENSMUST00000218553.2
protein tyrosine phosphatase, receptor type, B
chr10_-_89342493 1.23 ENSMUST00000058126.15
ENSMUST00000105296.9
nuclear receptor subfamily 1, group H, member 4
chr10_-_127206300 1.22 ENSMUST00000026472.10
inhibin beta-C
chr11_+_68986043 1.21 ENSMUST00000101004.9
period circadian clock 1
chr11_+_115353290 1.19 ENSMUST00000106532.4
ENSMUST00000092445.12
ENSMUST00000153466.2
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr7_-_25358406 1.18 ENSMUST00000071329.8
branched chain ketoacid dehydrogenase E1, alpha polypeptide
chr1_-_162726053 1.14 ENSMUST00000143123.3
flavin containing monooxygenase 2
chr11_+_67167950 1.14 ENSMUST00000019625.12
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr9_+_106324952 1.10 ENSMUST00000215475.2
ENSMUST00000187106.7
ENSMUST00000190167.7
abhydrolase domain containing 14b
chr2_+_133394079 1.08 ENSMUST00000028836.7
bone morphogenetic protein 2
chr8_-_95405234 0.99 ENSMUST00000213043.2
plasma membrane proteolipid
chr7_+_26895206 0.95 ENSMUST00000179391.8
ENSMUST00000108379.8
cDNA sequence BC024978
chr14_+_66074751 0.92 ENSMUST00000022614.7
coiled-coil domain containing 25
chr11_+_50917831 0.90 ENSMUST00000072152.2
olfactory receptor 54
chr15_-_101621332 0.90 ENSMUST00000023709.7
keratin 5
chr6_+_78347844 0.89 ENSMUST00000096904.6
ENSMUST00000203266.2
regenerating islet-derived 3 beta
chr11_+_67090878 0.87 ENSMUST00000124516.8
ENSMUST00000018637.15
ENSMUST00000129018.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chrX_+_37405054 0.85 ENSMUST00000016471.9
ENSMUST00000115134.2
ATPase, (Na+)/K+ transporting, beta 4 polypeptide
chr2_+_33106062 0.83 ENSMUST00000004208.7
angiopoietin-like 2
chr3_+_122277372 0.82 ENSMUST00000197073.2
breast cancer anti-estrogen resistance 3
chr16_+_20492014 0.80 ENSMUST00000154950.8
ENSMUST00000115461.8
ENSMUST00000136713.5
eukaryotic translation initiation factor 4, gamma 1
chr8_-_23680954 0.77 ENSMUST00000209507.2
glycerol-3-phosphate acyltransferase 4
chr3_+_87855973 0.77 ENSMUST00000005019.6
cellular retinoic acid binding protein II
chr5_-_123887434 0.76 ENSMUST00000182955.8
ENSMUST00000182489.8
ENSMUST00000183147.9
ENSMUST00000050827.14
ENSMUST00000057795.12
ENSMUST00000111515.8
ENSMUST00000182309.8
arginine/serine-rich coiled-coil 2
chrX_-_47297436 0.75 ENSMUST00000037960.11
zinc finger, DHHC domain containing 9
chr15_-_101833160 0.73 ENSMUST00000023797.8
keratin 4
chr1_+_152275575 0.73 ENSMUST00000044311.9
collagen beta(1-O)galactosyltransferase 2
chr16_+_42727926 0.72 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr1_-_172047282 0.72 ENSMUST00000170700.2
ENSMUST00000003554.11
calsequestrin 1
chr4_+_105014536 0.72 ENSMUST00000064139.8
phospholipid phosphatase 3
chr2_+_34661982 0.71 ENSMUST00000028222.13
ENSMUST00000100171.3
heat shock protein 5
chr2_+_33106121 0.70 ENSMUST00000193373.3
angiopoietin-like 2
chr6_+_34723304 0.70 ENSMUST00000142716.3
caldesmon 1
chrX_-_8059597 0.69 ENSMUST00000143223.2
ENSMUST00000033509.15
phenylalkylamine Ca2+ antagonist (emopamil) binding protein
chr1_-_155293141 0.68 ENSMUST00000111775.8
ENSMUST00000111774.2
xenotropic and polytropic retrovirus receptor 1
chr10_+_57661010 0.68 ENSMUST00000165013.2
fatty acid binding protein 7, brain
chr16_+_22676589 0.68 ENSMUST00000004574.14
ENSMUST00000178320.2
ENSMUST00000166487.10
DnaJ heat shock protein family (Hsp40) member B11
chr3_+_89987749 0.67 ENSMUST00000127955.2
tropomyosin 3, gamma
chrX_-_105647282 0.65 ENSMUST00000113480.2
cysteinyl leukotriene receptor 1
chr6_-_33037107 0.65 ENSMUST00000115091.2
ENSMUST00000127666.8
coiled-coil-helix-coiled-coil-helix domain containing 3
chr3_+_63203235 0.65 ENSMUST00000194134.6
membrane metallo endopeptidase
chr4_+_102427247 0.64 ENSMUST00000097950.9
phosphodiesterase 4B, cAMP specific
chrX_-_111315519 0.64 ENSMUST00000124335.8
spermidine/spermine N1-acetyl transferase-like 1
chr2_-_69172944 0.64 ENSMUST00000102709.8
ENSMUST00000102710.10
ENSMUST00000180142.2
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr4_-_123466853 0.61 ENSMUST00000238555.2
microtubule-actin crosslinking factor 1
chr10_+_4561974 0.61 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chr8_+_91554933 0.61 ENSMUST00000048665.8
chromodomain helicase DNA binding protein 9
chr3_-_144738526 0.60 ENSMUST00000029919.7
chloride channel accessory 1
chr2_-_113883285 0.60 ENSMUST00000090269.7
actin, alpha, cardiac muscle 1
chrX_-_50294652 0.60 ENSMUST00000114875.8
muscleblind like splicing factor 3
chr6_-_33037191 0.60 ENSMUST00000066379.11
coiled-coil-helix-coiled-coil-helix domain containing 3
chr6_-_5256282 0.59 ENSMUST00000031773.9
paraoxonase 3
chr13_+_120151915 0.59 ENSMUST00000225543.2
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
chr9_+_43978369 0.58 ENSMUST00000177054.8
ubiquitin specific peptidase 2
chr7_+_126396779 0.58 ENSMUST00000205324.2
TLC domain containing 3B
chr19_+_8828132 0.58 ENSMUST00000235683.2
ENSMUST00000096257.3
LRRN4 C-terminal like
chr4_-_141351110 0.57 ENSMUST00000038661.8
solute carrier family 25, member 34
chr3_+_99203818 0.55 ENSMUST00000150756.3
T-box 15
chr16_+_51851917 0.55 ENSMUST00000227062.2
Casitas B-lineage lymphoma b
chr12_+_36042899 0.55 ENSMUST00000020898.12
anterior gradient 2
chr2_-_5680801 0.55 ENSMUST00000114987.4
calcium/calmodulin-dependent protein kinase ID
chr13_+_25127127 0.54 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr1_+_164624200 0.54 ENSMUST00000027861.6
dermatopontin
chr19_-_11806388 0.53 ENSMUST00000061235.3
olfactory receptor 1417
chr14_-_31503869 0.53 ENSMUST00000227089.2
ankyrin repeat domain 28
chr19_+_56276375 0.53 ENSMUST00000166049.8
hyaluronic acid binding protein 2
chr5_-_151351628 0.53 ENSMUST00000202365.2
ENSMUST00000186838.2
predicted gene 42906
RIKEN cDNA D730045B01 gene
chrX_+_162691978 0.52 ENSMUST00000069041.15
adaptor-related protein complex 1, sigma 2 subunit
chrX_-_99456185 0.51 ENSMUST00000033567.15
acyl-CoA wax alcohol acyltransferase 2
chr7_-_5128936 0.51 ENSMUST00000147835.4
RAS-like, family 2, locus 9
chrX_-_47297746 0.51 ENSMUST00000088935.4
zinc finger, DHHC domain containing 9
chr16_+_51851588 0.50 ENSMUST00000114471.3
Casitas B-lineage lymphoma b
chr11_+_98274637 0.49 ENSMUST00000008021.3
titin-cap
chr11_+_77353431 0.49 ENSMUST00000130255.2
coronin 6
chr6_+_15727798 0.49 ENSMUST00000128849.3
MyoD family inhibitor domain containing
chr4_-_129121676 0.49 ENSMUST00000106051.8
expressed sequence C77080
chr5_-_31250817 0.49 ENSMUST00000031037.14
solute carrier family 30 (zinc transporter), member 3
chr7_+_114344920 0.49 ENSMUST00000136645.8
ENSMUST00000169913.8
INSC spindle orientation adaptor protein
chr4_+_95467701 0.48 ENSMUST00000150830.2
ENSMUST00000134012.9
FGGY carbohydrate kinase domain containing
chrX_+_100420873 0.47 ENSMUST00000052130.14
gap junction protein, beta 1
chr14_-_36628263 0.47 ENSMUST00000183007.2
coiled-coil serine rich 2
chr1_-_162687488 0.47 ENSMUST00000134098.8
ENSMUST00000111518.3
flavin containing monooxygenase 1
chr11_-_83959380 0.46 ENSMUST00000164891.8
dual specificity phosphatase 14
chr6_-_115228800 0.45 ENSMUST00000205131.2
tissue inhibitor of metalloproteinase 4
chr19_+_56276343 0.44 ENSMUST00000095948.11
hyaluronic acid binding protein 2
chr10_-_125164826 0.43 ENSMUST00000211781.2
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr1_-_57008986 0.43 ENSMUST00000176759.2
ENSMUST00000177424.2
special AT-rich sequence binding protein 2
chr7_+_140425460 0.43 ENSMUST00000035300.7
secretoglobin, family 1C, member 1
chr12_+_84687721 0.43 ENSMUST00000221915.2
ENSMUST00000166772.9
vertebrae development associated
chr17_+_45817750 0.43 ENSMUST00000024733.9
alanyl-tRNA synthetase 2, mitochondrial
chr5_+_92535705 0.43 ENSMUST00000138687.2
ENSMUST00000124509.2
ADP-ribosyltransferase 3
chr14_+_65903840 0.43 ENSMUST00000022610.15
scavenger receptor class A, member 5
chr12_-_84408576 0.43 ENSMUST00000021659.2
ENSMUST00000065536.9
family with sequence similarity 161, member B
chr9_+_89791943 0.42 ENSMUST00000189545.2
ENSMUST00000034909.11
ENSMUST00000034912.6
RAS protein-specific guanine nucleotide-releasing factor 1
chr10_-_12743915 0.42 ENSMUST00000219584.2
utrophin
chr13_+_93440265 0.42 ENSMUST00000109494.8
homer scaffolding protein 1
chr10_-_75658355 0.42 ENSMUST00000160211.2
glutathione S-transferase, theta 4
chr10_-_12744025 0.41 ENSMUST00000219660.2
utrophin
chr13_+_42862957 0.39 ENSMUST00000066928.12
ENSMUST00000148891.8
phosphatase and actin regulator 1
chr5_+_149335214 0.39 ENSMUST00000093110.12
mesenteric estrogen dependent adipogenesis
chr3_-_121076745 0.39 ENSMUST00000135818.8
ENSMUST00000137234.2
TLC domain containing 4
chr15_-_78090591 0.39 ENSMUST00000120592.2
parvalbumin
chr10_-_89093441 0.38 ENSMUST00000182341.8
ENSMUST00000182613.8
anoctamin 4
chr19_-_34856853 0.38 ENSMUST00000036584.13
pantothenate kinase 1
chr18_-_23171713 0.38 ENSMUST00000081423.13
nucleolar protein 4
chr10_-_105410280 0.38 ENSMUST00000061506.9
transmembrane and tetratricopeptide repeat containing 2
chr16_+_41353212 0.38 ENSMUST00000078873.11
limbic system-associated membrane protein
chr2_-_142743354 0.38 ENSMUST00000211861.2
kinesin family member 16B
chrX_-_111316476 0.37 ENSMUST00000026601.3
spermidine/spermine N1-acetyl transferase-like 1
chr5_+_92535532 0.37 ENSMUST00000145072.8
ADP-ribosyltransferase 3
chr11_+_67689094 0.37 ENSMUST00000168612.8
dehydrogenase/reductase (SDR family) member 7C
chrX_+_162692126 0.37 ENSMUST00000033734.14
ENSMUST00000112294.9
adaptor-related protein complex 1, sigma 2 subunit
chr2_-_22930188 0.37 ENSMUST00000114544.10
ENSMUST00000139038.8
ENSMUST00000126112.8
ENSMUST00000178908.2
ENSMUST00000078977.14
ENSMUST00000140164.8
ENSMUST00000149719.8
abl interactor 1
chr7_+_27879650 0.37 ENSMUST00000172467.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr11_-_78313043 0.37 ENSMUST00000001122.6
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr6_+_78347636 0.37 ENSMUST00000204873.3
regenerating islet-derived 3 beta
chr2_-_147028309 0.36 ENSMUST00000067075.7
NK2 homeobox 2
chr8_-_37200051 0.36 ENSMUST00000098826.10
deleted in liver cancer 1
chr9_+_21095399 0.36 ENSMUST00000115458.9
phosphodiesterase 4A, cAMP specific
chr15_+_10952418 0.36 ENSMUST00000022853.15
ENSMUST00000110523.2
C1q and tumor necrosis factor related protein 3
chr3_-_7678785 0.35 ENSMUST00000194279.6
interleukin 7
chr4_-_129155185 0.35 ENSMUST00000145261.8
expressed sequence C77080
chr8_+_91555449 0.35 ENSMUST00000109614.9
chromodomain helicase DNA binding protein 9
chr17_-_15163362 0.35 ENSMUST00000238668.2
ENSMUST00000228330.2
WD repeat domain 27
chr8_+_31581635 0.35 ENSMUST00000161713.2
dual specificity phosphatase 26 (putative)
chr1_+_93271340 0.34 ENSMUST00000185498.7
protein phosphatase 1, regulatory subunit 7
chr2_+_20742115 0.34 ENSMUST00000114606.8
ENSMUST00000114608.3
enhancer trap locus 4
chr16_-_3726503 0.34 ENSMUST00000115859.8
RIKEN cDNA 1700037C18 gene
chr11_+_115802828 0.33 ENSMUST00000132961.2
small integral membrane protein 6
chr9_-_87613301 0.33 ENSMUST00000034991.8
T-box18
chr2_-_160155536 0.33 ENSMUST00000109475.3
predicted gene 826
chr5_-_104125226 0.33 ENSMUST00000048118.15
hydroxysteroid (17-beta) dehydrogenase 13
chr5_+_24618380 0.33 ENSMUST00000049346.10
acid-sensing (proton-gated) ion channel 3
chr12_-_45120895 0.30 ENSMUST00000120531.8
ENSMUST00000143376.8
syntaxin binding protein 6 (amisyn)
chr5_-_147662798 0.30 ENSMUST00000110529.6
ENSMUST00000031653.12
FMS-like tyrosine kinase 1
chr6_-_5256225 0.30 ENSMUST00000125686.8
paraoxonase 3
chr12_-_70394074 0.30 ENSMUST00000223160.2
ENSMUST00000222316.2
ENSMUST00000167755.3
ENSMUST00000110520.10
ENSMUST00000110522.10
ENSMUST00000221041.2
ENSMUST00000222603.3
tripartite motif-containing 9
chr19_-_11833365 0.30 ENSMUST00000079875.4
olfactory receptor 1418
chr7_+_133239272 0.30 ENSMUST00000051169.13
erythroid differentiation regulatory factor 1
chr12_-_55539372 0.30 ENSMUST00000021413.9
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr15_-_64794139 0.30 ENSMUST00000023007.7
ENSMUST00000228014.2
adenylate cyclase 8
chr13_+_49761506 0.29 ENSMUST00000021822.7
osteoglycin
chr7_+_133239414 0.29 ENSMUST00000128901.9
erythroid differentiation regulatory factor 1
chr11_+_49500090 0.29 ENSMUST00000020617.3
FMS-like tyrosine kinase 4
chr6_+_113460258 0.28 ENSMUST00000032422.6
cysteine-rich with EGF-like domains 1
chr11_+_69047815 0.28 ENSMUST00000036424.3
arachidonate 12-lipoxygenase, 12R type
chr5_-_104125270 0.28 ENSMUST00000112803.3
hydroxysteroid (17-beta) dehydrogenase 13
chr10_+_21869776 0.28 ENSMUST00000092673.11
serum/glucocorticoid regulated kinase 1
chr7_+_141276575 0.28 ENSMUST00000185406.8
mucin 2
chr11_-_43727071 0.28 ENSMUST00000167574.2
adrenergic receptor, alpha 1b
chrX_+_113384297 0.28 ENSMUST00000133447.2
kelch-like 4
chr3_-_89186940 0.27 ENSMUST00000118860.2
ENSMUST00000029566.9
ephrin A1
chr1_-_86353932 0.27 ENSMUST00000212541.2
neuromedin U receptor 1
chr3_-_7678796 0.27 ENSMUST00000192202.6
interleukin 7
chr11_-_114686712 0.27 ENSMUST00000000206.4
BTB (POZ) domain containing 17
chr15_-_98769056 0.27 ENSMUST00000178486.9
ENSMUST00000023741.16
lysine (K)-specific methyltransferase 2D
chr6_+_83055581 0.27 ENSMUST00000177177.8
ENSMUST00000176089.2
polycomb group ring finger 1
chrX_-_50294867 0.27 ENSMUST00000114876.9
muscleblind like splicing factor 3
chr1_+_169757498 0.26 ENSMUST00000175731.3
coiled-coil domain containing 190
chr9_-_123546605 0.26 ENSMUST00000163207.2
leucine zipper transcription factor-like 1
chr6_-_125290809 0.26 ENSMUST00000032489.8
lymphotoxin B receptor
chr10_-_125164399 0.26 ENSMUST00000063318.10
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr17_-_14279793 0.26 ENSMUST00000186636.3
predicted gene 7358
chr4_-_42661893 0.26 ENSMUST00000108006.4
interleukin 11 receptor, alpha chain 2
chr5_-_104125192 0.25 ENSMUST00000120320.8
hydroxysteroid (17-beta) dehydrogenase 13
chr18_+_34380738 0.25 ENSMUST00000066133.7
APC, WNT signaling pathway regulator
chr11_-_84771021 0.25 ENSMUST00000067058.3
ENSMUST00000108080.3
phosphatidylinositol glycan anchor biosynthesis, class W

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.9 2.7 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.7 2.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.6 1.7 GO:0002481 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.5 1.5 GO:1903920 positive regulation of actin filament severing(GO:1903920)
0.5 2.3 GO:0009115 xanthine catabolic process(GO:0009115)
0.3 9.1 GO:0017144 drug metabolic process(GO:0017144)
0.3 1.2 GO:0034971 histone H3-R17 methylation(GO:0034971) bile acid signaling pathway(GO:0038183)
0.3 2.1 GO:0002003 angiotensin maturation(GO:0002003)
0.3 2.4 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3 1.1 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.2 4.8 GO:0042448 progesterone metabolic process(GO:0042448)
0.2 0.7 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 0.9 GO:0046226 coumarin metabolic process(GO:0009804) coumarin catabolic process(GO:0046226)
0.2 2.4 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.2 5.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 2.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 8.6 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.2 1.0 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 1.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.2 3.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 9.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 0.8 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.2 0.6 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.2 0.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 0.3 GO:2000729 mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 1.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 1.5 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.7 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330)
0.1 0.9 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 0.6 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.4 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 1.5 GO:0036476 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 1.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 2.8 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.6 GO:0046618 drug export(GO:0046618)
0.1 1.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 1.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.3 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 1.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.7 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.7 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.3 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.1 0.5 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 1.3 GO:0042407 cristae formation(GO:0042407)
0.1 2.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.3 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.5 GO:0097501 stress response to metal ion(GO:0097501)
0.1 0.3 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.4 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 0.2 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.1 1.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.5 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.1 0.4 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 1.1 GO:0030049 muscle filament sliding(GO:0030049)
0.1 1.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.3 GO:0014028 notochord formation(GO:0014028)
0.1 0.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.3 GO:0050968 sensory perception of sour taste(GO:0050915) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 0.2 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.1 0.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:0007403 glial cell fate determination(GO:0007403)
0.0 0.6 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.2 GO:0002786 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.0 0.3 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.3 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.2 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0021558 trochlear nerve development(GO:0021558)
0.0 0.2 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0 0.5 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.2 GO:0060578 subthalamic nucleus development(GO:0021763) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.2 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.6 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.6 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.5 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.0 0.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.5 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.6 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 1.4 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.1 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.7 GO:0016556 mRNA modification(GO:0016556)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.6 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:0033280 response to vitamin D(GO:0033280)
0.0 0.5 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.7 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.9 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 0.9 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 0.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.0 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.4 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.5 GO:0060487 lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 4.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 0.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 0.9 GO:0070722 Tle3-Aes complex(GO:0070722)
0.2 0.6 GO:0042643 actomyosin, actin portion(GO:0042643)
0.2 1.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 1.3 GO:0061617 MICOS complex(GO:0061617)
0.2 2.1 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.4 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.1 3.1 GO:0045095 keratin filament(GO:0045095)
0.1 1.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.3 GO:0042588 zymogen granule(GO:0042588)
0.1 2.0 GO:0032982 myosin filament(GO:0032982)
0.1 0.7 GO:0030478 actin cap(GO:0030478)
0.1 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 8.1 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.9 GO:0070938 contractile ring(GO:0070938)
0.0 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 2.1 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 4.7 GO:0072562 blood microparticle(GO:0072562)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 3.3 GO:0044306 neuron projection terminus(GO:0044306)
0.0 5.0 GO:0030141 secretory granule(GO:0030141)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 22.4 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.6 5.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.5 2.3 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.4 9.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.4 1.6 GO:0004103 choline kinase activity(GO:0004103)
0.4 1.2 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.4 1.5 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 2.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 3.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 1.0 GO:0019809 spermidine binding(GO:0019809)
0.3 9.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.2 1.2 GO:0038181 bile acid receptor activity(GO:0038181)
0.2 4.8 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 0.9 GO:0004063 aryldialkylphosphatase activity(GO:0004063)
0.2 1.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.6 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 0.7 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 0.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 0.5 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.7 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.5 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 2.1 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.5 GO:0070287 ferritin receptor activity(GO:0070287)
0.1 0.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.7 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.5 GO:0051373 FATZ binding(GO:0051373)
0.1 0.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.3 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.1 3.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 4.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 2.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.5 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.4 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.2 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.8 GO:0019841 retinol binding(GO:0019841)
0.0 0.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.3 GO:0017166 vinculin binding(GO:0017166)
0.0 1.1 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0052795 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 4.3 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.5 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 3.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 6.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.3 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.9 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 6.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 3.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.3 PID BMP PATHWAY BMP receptor signaling
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 4.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.6 1.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 4.8 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.3 5.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 2.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 3.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 2.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 3.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 0.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 2.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway