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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nkx3-1

Z-value: 1.81

Motif logo

Transcription factors associated with Nkx3-1

Gene Symbol Gene ID Gene Info
ENSMUSG00000022061.9 Nkx3-1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx3-1mm39_v1_chr14_+_69428087_694281400.086.4e-01Click!

Activity profile of Nkx3-1 motif

Sorted Z-values of Nkx3-1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx3-1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_137157824 43.15 ENSMUST00000102522.5
chymotrypsin-like elastase family, member 3B
chr19_+_58748132 34.01 ENSMUST00000026081.5
pancreatic lipase-related protein 2
chr6_-_41012435 33.78 ENSMUST00000031931.6
RIKEN cDNA 2210010C04 gene
chr6_+_78402956 30.29 ENSMUST00000079926.6
regenerating islet-derived 1
chr3_-_113325938 23.38 ENSMUST00000132353.2
amylase 2a1
chr3_-_113198765 19.06 ENSMUST00000179568.3
amylase 2a4
chr3_-_113231368 17.63 ENSMUST00000179314.3
amylase 2a3
chr3_-_113263974 17.24 ENSMUST00000098667.5
amylase 2a2
chr3_-_113166153 17.14 ENSMUST00000098673.5
amylase 2a5
chr4_-_137137088 15.83 ENSMUST00000024200.7
chymotrypsin-like elastase family, member 3A
chr4_-_115353326 9.95 ENSMUST00000030487.3
cytochrome P450, family 4, subfamily a, polypeptide 14
chr5_-_145816774 5.96 ENSMUST00000035918.8
cytochrome P450, family 3, subfamily a, polypeptide 11
chr5_-_145742672 5.49 ENSMUST00000067479.6
cytochrome P450, family 3, subfamily a, polypeptide 44
chr1_+_139429430 4.98 ENSMUST00000027615.7
coagulation factor XIII, beta subunit
chr13_-_41981893 4.34 ENSMUST00000137905.2
androgen dependent TFPI regulating protein
chr13_-_41981812 4.30 ENSMUST00000223337.2
ENSMUST00000221691.2
androgen dependent TFPI regulating protein
chr5_-_145406533 3.97 ENSMUST00000031633.5
cytochrome P450, family 3, subfamily a, polypeptide 16
chr3_+_146276147 3.59 ENSMUST00000199489.5
urate oxidase
chr13_-_42000958 3.25 ENSMUST00000072012.10
androgen dependent TFPI regulating protein
chrX_-_74918122 3.21 ENSMUST00000033547.14
plastin 3 (T-isoform)
chr18_+_12732951 3.20 ENSMUST00000234255.2
ENSMUST00000169401.8
tetratricopeptide repeat domain 39C
chrX_-_74918709 3.19 ENSMUST00000114059.10
plastin 3 (T-isoform)
chr9_+_77829191 3.04 ENSMUST00000133757.8
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr9_-_103099262 3.03 ENSMUST00000170904.2
transferrin
chr5_-_134776101 2.93 ENSMUST00000015138.13
elastin
chr6_+_54016543 2.50 ENSMUST00000046856.14
chimerin 2
chr11_-_21320452 2.48 ENSMUST00000102875.11
UDP-glucose pyrophosphorylase 2
chr3_+_62327089 2.46 ENSMUST00000161057.2
Rho guanine nucleotide exchange factor (GEF) 26
chr8_+_46984016 2.43 ENSMUST00000152423.2
acyl-CoA synthetase long-chain family member 1
chr9_+_74883377 2.39 ENSMUST00000081746.7
family with sequence similarity 214, member A
chr8_+_114860297 2.35 ENSMUST00000073521.12
ENSMUST00000066514.13
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr11_-_121410152 2.34 ENSMUST00000092298.6
zinc finger protein 750
chr11_-_61269131 2.26 ENSMUST00000148671.2
solute carrier family 47, member 1
chr6_-_108162513 2.21 ENSMUST00000167338.8
ENSMUST00000172188.2
ENSMUST00000032191.16
sulfatase modifying factor 1
chr8_+_114860375 2.19 ENSMUST00000147605.8
ENSMUST00000134593.2
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr5_-_145521533 2.14 ENSMUST00000075837.8
cytochrome P450, family 3, subfamily a, polypeptide 41B
chr15_-_96918203 2.13 ENSMUST00000166223.2
solute carrier family 38, member 4
chr8_+_114860342 2.12 ENSMUST00000109109.8
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr8_-_96534043 2.09 ENSMUST00000213046.2
CCR4-NOT transcription complex, subunit 1
chr9_+_106325860 2.08 ENSMUST00000185527.3
abhydrolase domain containing 14b
chr2_-_84605764 2.07 ENSMUST00000111641.2
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr5_-_145656934 1.98 ENSMUST00000094111.6
cytochrome P450, family 3, subfamily a, polypeptide 41A
chr2_-_84605732 1.96 ENSMUST00000023994.10
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr1_-_162694076 1.90 ENSMUST00000046049.14
flavin containing monooxygenase 1
chr3_-_95595157 1.89 ENSMUST00000015994.4
ENSMUST00000148854.2
ENSMUST00000117782.8
ADAMTS-like 4
chr4_-_108075119 1.89 ENSMUST00000223127.2
ENSMUST00000043793.7
ENSMUST00000106690.9
zyg-11 family member A, cell cycle regulator
chr15_-_74869684 1.86 ENSMUST00000190188.2
ENSMUST00000189068.7
ENSMUST00000186526.7
ENSMUST00000187171.2
ENSMUST00000187994.7
lymphocyte antigen 6 complex, locus A
chr2_-_93680024 1.81 ENSMUST00000068513.11
ENSMUST00000041593.15
ENSMUST00000130077.2
1-aminocyclopropane-1-carboxylate synthase (non-functional)
chr7_-_126522014 1.68 ENSMUST00000134134.3
ENSMUST00000119781.8
ENSMUST00000121612.4
transmembrane protein 219
chr5_-_38649291 1.67 ENSMUST00000129099.8
solute carrier family 2 (facilitated glucose transporter), member 9
chr1_+_157334347 1.63 ENSMUST00000027881.15
SEC16 homolog B (S. cerevisiae)
chr1_-_174749379 1.63 ENSMUST00000055294.4
gremlin 2, DAN family BMP antagonist
chr12_+_8062331 1.63 ENSMUST00000171239.2
apolipoprotein B
chr1_+_157334298 1.62 ENSMUST00000086130.9
SEC16 homolog B (S. cerevisiae)
chr2_+_22959223 1.62 ENSMUST00000114523.10
acyl-Coenzyme A binding domain containing 5
chr11_+_68989763 1.59 ENSMUST00000021271.14
period circadian clock 1
chr6_-_83504471 1.57 ENSMUST00000141904.8
actin, gamma 2, smooth muscle, enteric
chr4_+_134124691 1.56 ENSMUST00000105870.8
platelet-activating factor acetylhydrolase 2
chr3_+_90155479 1.53 ENSMUST00000015467.9
solute carrier family 39 (zinc transporter), member 1
chr11_+_97576724 1.48 ENSMUST00000107583.3
CDGSH iron sulfur domain 3
chr6_-_83504756 1.38 ENSMUST00000152029.2
actin, gamma 2, smooth muscle, enteric
chr2_+_22959452 1.33 ENSMUST00000155602.4
acyl-Coenzyme A binding domain containing 5
chr16_-_11727262 1.23 ENSMUST00000127972.8
ENSMUST00000121750.2
ENSMUST00000096272.11
ENSMUST00000073371.7
calcineurin-like phosphoesterase domain containing 1
chr2_+_22958179 1.21 ENSMUST00000227663.2
ENSMUST00000028121.15
ENSMUST00000227809.2
ENSMUST00000144088.2
acyl-Coenzyme A binding domain containing 5
chr18_-_12995681 1.19 ENSMUST00000121808.8
ENSMUST00000118313.8
oxysterol binding protein-like 1A
chr1_+_171330978 1.14 ENSMUST00000081527.2
Aly/REF export factor 2
chr3_+_57332735 1.07 ENSMUST00000029377.8
transmembrane 4 superfamily member 4
chr11_-_58504307 1.03 ENSMUST00000048801.8
LY6/PLAUR domain containing 8 like
chr5_+_8710059 1.02 ENSMUST00000047753.5
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
chr17_+_29487881 0.98 ENSMUST00000234845.2
ENSMUST00000235038.2
ENSMUST00000235050.2
ENSMUST00000120346.9
ENSMUST00000234377.2
ENSMUST00000235074.2
ENSMUST00000235040.2
ENSMUST00000234256.2
ENSMUST00000234459.2
cDNA sequence BC004004
chr10_-_4382311 0.94 ENSMUST00000126102.8
ENSMUST00000131853.2
ENSMUST00000042251.11
required for meiotic nuclear division 1 homolog
chr10_-_128047658 0.94 ENSMUST00000061995.10
SPRY domain containing 4
chr3_-_49711706 0.92 ENSMUST00000191794.2
protocadherin 18
chr15_-_74869483 0.90 ENSMUST00000023248.13
lymphocyte antigen 6 complex, locus A
chr9_+_103917821 0.90 ENSMUST00000216593.2
ENSMUST00000147249.3
nephronophthisis 3 (adolescent)
predicted gene 28305
chr13_+_51562675 0.84 ENSMUST00000087978.5
sphingosine-1-phosphate receptor 3
chr2_+_25293056 0.83 ENSMUST00000071442.12
neural proliferation, differentiation and control 1
chr10_-_59277570 0.82 ENSMUST00000009798.5
oncoprotein induced transcript 3
chr8_-_96534085 0.78 ENSMUST00000098473.11
ENSMUST00000211887.2
CCR4-NOT transcription complex, subunit 1
chr9_+_89081407 0.78 ENSMUST00000138109.2
predicted gene 29094
chr17_-_78725510 0.77 ENSMUST00000234029.2
ENSMUST00000234530.2
ENSMUST00000234052.2
ENSMUST00000070039.14
ENSMUST00000112487.3
fasciculation and elongation protein zeta 2 (zygin II)
chr19_-_10217968 0.71 ENSMUST00000189897.2
ENSMUST00000186056.7
ENSMUST00000088013.12
myelin regulatory factor
chrX_+_7786061 0.69 ENSMUST00000041096.4
proprotein convertase subtilisin/kexin type 1 inhibitor
chr17_+_35354172 0.67 ENSMUST00000172571.8
ENSMUST00000173491.8
BCL2-associated athanogene 6
chr2_+_25293140 0.67 ENSMUST00000154809.8
ENSMUST00000055921.14
ENSMUST00000141567.8
neural proliferation, differentiation and control 1
chr1_-_155910567 0.61 ENSMUST00000141878.8
torsin A interacting protein 1
chr9_+_89081262 0.59 ENSMUST00000068569.5
B cell leukemia/lymphoma 2 related protein A1b
chr9_+_78099229 0.56 ENSMUST00000034903.7
glutathione S-transferase, alpha 4
chr13_+_35059285 0.54 ENSMUST00000077853.5
pre-mRNA processing factor 4B
chr6_+_94477294 0.52 ENSMUST00000061118.11
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26
chr13_+_21496295 0.51 ENSMUST00000004453.9
glutathione peroxidase 6
chr8_-_106738514 0.50 ENSMUST00000058579.7
DEAD box helicase 28
chr11_-_101169753 0.50 ENSMUST00000168089.2
ENSMUST00000017332.4
cytochrome C oxidase assembly factor 3
chr11_-_103588487 0.50 ENSMUST00000107013.3
golgi SNAP receptor complex member 2
chr6_-_69415741 0.47 ENSMUST00000103354.3
immunoglobulin kappa variable 4-59
chr17_-_15784582 0.45 ENSMUST00000147532.8
PR domain containing 9
chr3_-_54962899 0.44 ENSMUST00000199144.5
cyclin A1
chr3_-_57483175 0.43 ENSMUST00000029380.14
WW domain containing transcription regulator 1
chr4_+_43406435 0.43 ENSMUST00000098106.9
ENSMUST00000139198.2
RUN and SH3 domain containing 2
chr5_+_21577640 0.42 ENSMUST00000035799.6
fibrinogen-like protein 2
chr7_+_126844359 0.42 ENSMUST00000205583.2
zinc finger protein 771
chr9_-_20887967 0.41 ENSMUST00000214218.2
sphingosine-1-phosphate receptor 2
chr12_+_101370932 0.39 ENSMUST00000055156.5
cation channel sperm associated auxiliary subunit beta
chr2_+_132688558 0.39 ENSMUST00000028835.13
ENSMUST00000110122.10
cardiolipin synthase 1
chr10_+_18345706 0.39 ENSMUST00000162891.8
ENSMUST00000100054.4
NHS-like 1
chr17_+_35354148 0.36 ENSMUST00000166426.9
ENSMUST00000025250.14
BCL2-associated athanogene 6
chr17_+_85264134 0.36 ENSMUST00000112305.10
protein phosphatase 1B, magnesium dependent, beta isoform
chr2_-_112198366 0.36 ENSMUST00000028551.4
ER membrane protein complex subunit 4
chr3_-_54962922 0.35 ENSMUST00000197238.5
cyclin A1
chr15_+_79113563 0.34 ENSMUST00000018295.14
ENSMUST00000053926.12
protein interacting with C kinase 1
predicted gene, 49486
chr17_-_66079681 0.33 ENSMUST00000070673.9
RAB31, member RAS oncogene family
chr9_-_62444318 0.33 ENSMUST00000048043.12
coronin, actin binding protein, 2B
chr7_+_12568647 0.32 ENSMUST00000004614.15
zinc finger protein 110
chr18_+_37106851 0.32 ENSMUST00000192631.2
protocadherin alpha 7
chrX_-_8072714 0.32 ENSMUST00000089403.10
ENSMUST00000077595.12
ENSMUST00000089402.10
ENSMUST00000082320.12
porcupine O-acyltransferase
chr7_-_23936985 0.30 ENSMUST00000206362.2
zinc finger protein 109
chr5_+_73071607 0.28 ENSMUST00000144843.8
SLAIN motif family, member 2
chr6_-_124834670 0.27 ENSMUST00000023958.10
prolyl 3-hydroxylase 3
chr16_-_48592319 0.26 ENSMUST00000239408.2
T cell receptor associated transmembrane adaptor 1
chr6_-_69282389 0.25 ENSMUST00000103350.3
immunoglobulin kappa variable 4-68
chr4_+_116565898 0.25 ENSMUST00000135499.8
coiled-coil domain containing 163
chr6_-_69261303 0.24 ENSMUST00000103349.2
immunoglobulin kappa variable 4-69
chr8_-_41494890 0.22 ENSMUST00000051379.14
mitochondrial tumor suppressor 1
chr3_-_100936859 0.22 ENSMUST00000147399.9
CD101 antigen
chrY_+_51121799 0.21 ENSMUST00000185327.7
predicted gene, 21117
chrY_+_73680584 0.21 ENSMUST00000189346.2
predicted gene, 20903
chr5_-_86893645 0.20 ENSMUST00000161306.2
transmembrane protease, serine 11e
chr6_-_69626340 0.20 ENSMUST00000198328.2
immunoglobulin kappa variable 4-53
chr6_+_68279392 0.20 ENSMUST00000103322.3
immunoglobulin kappa variable 2-109
chrY_-_35876871 0.20 ENSMUST00000188585.7
predicted gene, 20896
chrY_+_81469276 0.20 ENSMUST00000187135.2
predicted gene, 20911
chrY_+_88064584 0.20 ENSMUST00000187146.2
predicted gene 28102
chrY_-_35087178 0.20 ENSMUST00000186996.7
predicted gene, 20855
chrY_+_87128072 0.20 ENSMUST00000189543.7
predicted gene, 21477
chrY_+_71480718 0.20 ENSMUST00000188958.2
predicted gene, 20869
chrY_+_84757954 0.19 ENSMUST00000186110.2
predicted gene, 21409
chrY_+_84108548 0.19 ENSMUST00000185776.7
predicted gene, 21095
chrY_+_49567735 0.19 ENSMUST00000189354.7
predicted gene, 21209
chrY_+_62199394 0.19 ENSMUST00000186938.7
predicted gene, 21518
chrY_+_79330834 0.19 ENSMUST00000185338.7
predicted gene, 20916
chrY_+_55728335 0.19 ENSMUST00000185713.7
predicted gene, 21858
chrY_-_72258387 0.19 ENSMUST00000191305.7
predicted gene, 20843
chrY_+_76772869 0.19 ENSMUST00000189238.2
predicted gene, 21173
chrY_-_68843997 0.19 ENSMUST00000191123.2
predicted gene, 20817
chrY_-_22046833 0.19 ENSMUST00000192521.2
predicted gene, 31571
chrY_+_75726591 0.19 ENSMUST00000188672.2
predicted gene, 20850
chrY_+_77704077 0.19 ENSMUST00000190551.7
predicted gene, 21650
chrY_+_57195716 0.19 ENSMUST00000189109.7
ENSMUST00000191355.7
ENSMUST00000190292.2
Sycp3 like Y-linked
chrY_+_57714225 0.19 ENSMUST00000190573.2
predicted gene 28961
chr2_+_3115250 0.19 ENSMUST00000072955.12
family with sequence similarity 171, member A1
chrY_+_65386218 0.19 ENSMUST00000190282.7
ENSMUST00000185550.7
predicted gene, 20736
chrY_+_52776619 0.19 ENSMUST00000191553.7
predicted gene, 21258
chrY_+_86073041 0.19 ENSMUST00000188754.2
predicted gene, 20820
chrY_-_20993657 0.19 ENSMUST00000191675.2
predicted gene, 29866
chrY_+_63236955 0.19 ENSMUST00000187768.2
predicted gene, 21627
chrY_+_71703312 0.19 ENSMUST00000189315.2
predicted gene, 20870
chrY_+_83042216 0.19 ENSMUST00000187165.2
predicted gene 28827
chrY_+_74481800 0.19 ENSMUST00000189924.2
predicted gene 29110
chrY_+_80938264 0.19 ENSMUST00000185340.2
predicted gene 28897
chrY_+_50604830 0.19 ENSMUST00000185245.2
predicted gene, 20883
chrY_-_22856736 0.19 ENSMUST00000192892.2
predicted gene, 21366
chrY_+_53840528 0.19 ENSMUST00000186578.2
predicted gene, 20929
chrY_+_82236496 0.19 ENSMUST00000185636.2
predicted gene, 21317
chrY_+_87562235 0.19 ENSMUST00000186493.2
predicted gene, 20906
chrY_-_36690635 0.19 ENSMUST00000185565.2
predicted gene, 20835
chrY_-_37214948 0.19 ENSMUST00000190782.2
predicted gene, 20905
chrY_+_61655274 0.19 ENSMUST00000189455.2
predicted gene, 21497
chrY_+_48861106 0.19 ENSMUST00000185924.2
predicted gene 28553
chrY_+_70453151 0.19 ENSMUST00000186890.7
predicted gene, 20888
chrY_+_51848699 0.19 ENSMUST00000187477.2
predicted gene, 20920
chrY_+_64481794 0.19 ENSMUST00000186004.2
predicted gene, 20908
chrY_+_55210299 0.19 ENSMUST00000187293.7
predicted gene, 20931
chrY_+_75207125 0.19 ENSMUST00000190173.2
predicted gene, 20814
chrY_+_78224262 0.19 ENSMUST00000185575.2
predicted gene 29564
chrY_+_80145048 0.19 ENSMUST00000187433.7
predicted gene, 21760
chr6_-_69245427 0.19 ENSMUST00000103348.3
immunoglobulin kappa chain variable 4-70
chr1_+_170983081 0.19 ENSMUST00000111334.2
myelin protein zero
chr5_-_21629661 0.19 ENSMUST00000115245.8
ENSMUST00000030552.7
coiled-coil domain containing 146
chr16_-_48592372 0.17 ENSMUST00000231701.3
T cell receptor associated transmembrane adaptor 1
chr1_-_173569301 0.17 ENSMUST00000042610.15
ENSMUST00000127730.2
interferon activated gene 207
chrY_+_8257907 0.16 ENSMUST00000186739.2
predicted gene, 20824
chr16_-_58695131 0.16 ENSMUST00000217377.2
olfactory receptor 177
chrY_+_89064075 0.16 ENSMUST00000186443.2
predicted gene, 21294
chr9_-_20888054 0.16 ENSMUST00000054197.7
sphingosine-1-phosphate receptor 2
chr5_-_110194352 0.15 ENSMUST00000167969.2
predicted gene, 17655
chr6_-_69553484 0.15 ENSMUST00000103357.4
immunoglobulin kappa variable 4-57
chr5_+_138159333 0.13 ENSMUST00000019638.15
ENSMUST00000110951.8
COP9 signalosome subunit 6
chrY_+_19113007 0.13 ENSMUST00000194086.2
predicted gene, 35134
chrY_+_14400710 0.12 ENSMUST00000192683.2
predicted gene, 30737
chrY_-_40272248 0.12 ENSMUST00000191443.7
predicted gene, 21865
chr14_-_55101505 0.12 ENSMUST00000142283.4
homeodomain leucine zipper-encoding gene
chrY_-_68306157 0.12 ENSMUST00000189084.7
ENSMUST00000189422.7
predicted gene, 20937
chr10_-_89568106 0.11 ENSMUST00000020109.5
ARP6 actin-related protein 6
chr14_+_53947359 0.11 ENSMUST00000103638.6
T cell receptor alpha variable 6-7-DV9
chr12_-_100125860 0.11 ENSMUST00000021596.9
ENSMUST00000221954.2
nrde-2 necessary for RNA interference, domain containing
chrY_-_38457583 0.11 ENSMUST00000185240.2
predicted gene, 20897
chr10_-_129751466 0.11 ENSMUST00000213438.2
olfactory receptor 816
chr1_-_4430481 0.10 ENSMUST00000027032.6
retinitis pigmentosa 1 (human)
chrY_-_26732144 0.10 ENSMUST00000189518.2
predicted gene, 20890
chrY_-_27477265 0.10 ENSMUST00000188744.2
predicted gene, 21488

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 34.0 GO:0019374 galactolipid metabolic process(GO:0019374)
1.8 30.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
1.7 6.7 GO:0034031 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
1.3 4.0 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.8 2.5 GO:0019255 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.5 1.6 GO:0060300 regulation of cytokine activity(GO:0060300)
0.4 3.0 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.4 4.2 GO:0030242 pexophagy(GO:0030242)
0.3 60.2 GO:0008203 cholesterol metabolic process(GO:0008203)
0.3 3.3 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.3 1.6 GO:0097167 circadian regulation of translation(GO:0097167)
0.3 1.0 GO:2001025 positive regulation of response to drug(GO:2001025)
0.3 3.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 6.4 GO:0051639 actin filament network formation(GO:0051639)
0.2 2.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2 5.2 GO:0046415 urate metabolic process(GO:0046415)
0.2 2.4 GO:0044539 long-chain fatty acid import(GO:0044539)
0.2 0.5 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 2.3 GO:0015695 organic cation transport(GO:0015695)
0.1 0.5 GO:0051182 coenzyme transport(GO:0051182)
0.1 1.0 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.9 GO:0048496 determination of pancreatic left/right asymmetry(GO:0035469) maintenance of organ identity(GO:0048496)
0.1 1.9 GO:0070995 NADPH oxidation(GO:0070995)
0.1 1.4 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 0.5 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 2.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 1.0 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 0.7 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.8 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.8 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.4 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.3 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.0 0.4 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 1.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 2.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.7 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.9 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 25.7 GO:0055114 oxidation-reduction process(GO:0055114)
0.0 2.9 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.2 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 64.3 GO:0042588 zymogen granule(GO:0042588)
0.8 3.0 GO:0097447 dendritic tree(GO:0097447)
0.6 2.9 GO:0071953 elastic fiber(GO:0071953)
0.5 1.6 GO:0034359 mature chylomicron(GO:0034359)
0.3 3.0 GO:0097433 dense body(GO:0097433)
0.3 2.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 0.9 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 0.8 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.2 0.3 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 1.9 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 1.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 6.4 GO:0032420 stereocilium(GO:0032420)
0.1 16.8 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.9 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 5.8 GO:0000800 lateral element(GO:0000800)
0.0 100.9 GO:0005615 extracellular space(GO:0005615)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 20.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 49.4 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 1.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 13.2 GO:0005783 endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.2 71.1 GO:0004556 alpha-amylase activity(GO:0004556)
2.4 19.5 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
2.1 34.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
1.4 10.0 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
1.3 6.7 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.5 2.4 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.4 3.0 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.4 91.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.4 2.5 GO:0070569 uridylyltransferase activity(GO:0070569)
0.3 1.0 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.3 3.6 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.3 3.0 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 2.3 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.2 1.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 1.6 GO:0036122 BMP binding(GO:0036122)
0.2 30.3 GO:0008083 growth factor activity(GO:0008083)
0.1 4.0 GO:0001848 complement binding(GO:0001848)
0.1 2.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.6 GO:0035473 lipase binding(GO:0035473)
0.1 1.6 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 0.3 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 0.5 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 3.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.3 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.0 2.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.7 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 1.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.6 GO:0051400 BH domain binding(GO:0051400)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 2.1 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 69.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 2.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 4.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 35.4 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.3 5.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 2.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 2.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 5.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 4.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 2.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 2.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling