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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nkx3-2

Z-value: 2.43

Motif logo

Transcription factors associated with Nkx3-2

Gene Symbol Gene ID Gene Info
ENSMUSG00000049691.9 Nkx3-2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx3-2mm39_v1_chr5_-_41921834_419218440.307.3e-02Click!

Activity profile of Nkx3-2 motif

Sorted Z-values of Nkx3-2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx3-2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_90638580 19.88 ENSMUST00000042755.7
ENSMUST00000200693.2
alpha fetoprotein
chr8_+_81220410 14.40 ENSMUST00000063359.8
glycophorin A
chr14_-_20319242 10.07 ENSMUST00000024155.9
potassium channel, subfamily K, member 16
chr8_-_73059104 8.95 ENSMUST00000075602.8
predicted pseudogene 10282
chr11_+_70529944 8.80 ENSMUST00000055184.7
ENSMUST00000108551.3
glycoprotein 1b, alpha polypeptide
chr2_-_165242307 8.47 ENSMUST00000029213.5
osteoclast stimulatory transmembrane protein
chr7_+_142559414 7.89 ENSMUST00000082008.12
ENSMUST00000105925.8
ENSMUST00000105924.8
tetraspanin 32
chr1_-_75110511 7.49 ENSMUST00000027405.6
solute carrier family 23 (nucleobase transporters), member 3
chr14_-_79539063 7.45 ENSMUST00000022595.8
regulator of cell cycle
chr7_+_142559375 6.97 ENSMUST00000075172.12
ENSMUST00000105923.8
tetraspanin 32
chrX_-_135104589 6.56 ENSMUST00000066819.11
transcription elongation factor A (SII)-like 5
chr7_+_78563964 6.23 ENSMUST00000120331.4
interferon-stimulated protein
chr10_+_79824418 5.79 ENSMUST00000004784.11
ENSMUST00000105374.2
calponin 2
chr1_+_91294133 5.66 ENSMUST00000086861.12
erythroferrone
chr15_-_103161237 5.58 ENSMUST00000154510.8
nuclear factor, erythroid derived 2
chr7_-_110581652 5.56 ENSMUST00000005751.13
inositol 1,4,5-triphosphate receptor associated 1
chr7_-_103502404 5.29 ENSMUST00000033229.5
hemoglobin Y, beta-like embryonic chain
chr15_+_34306812 5.29 ENSMUST00000226766.2
ENSMUST00000163455.9
ENSMUST00000022947.7
ENSMUST00000228570.2
ENSMUST00000227759.2
matrilin 2
chr11_+_120653613 4.88 ENSMUST00000105046.4
high mobility group AT-hook 1B
chr9_+_110856425 4.78 ENSMUST00000199313.2
lactotransferrin
chr10_+_127350820 4.62 ENSMUST00000035735.11
Ndufa4, mitochondrial complex associated like 2
chr4_-_140501507 4.46 ENSMUST00000026381.7
peptidyl arginine deiminase, type IV
chr8_-_86107593 4.44 ENSMUST00000122452.8
myosin light chain kinase 3
chr15_-_100567377 4.35 ENSMUST00000182814.8
ENSMUST00000238935.2
ENSMUST00000182068.8
ENSMUST00000182574.2
ENSMUST00000182775.8
bridging integrator 2
chr19_-_24533183 4.23 ENSMUST00000112673.9
ENSMUST00000025800.15
phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
chr4_+_130253925 4.21 ENSMUST00000105994.4
small nuclear ribonucleoprotein 40 (U5)
chr7_+_142559475 3.89 ENSMUST00000143512.3
tetraspanin 32
chrX_-_135104386 3.73 ENSMUST00000151592.8
ENSMUST00000131510.2
transcription elongation factor A (SII)-like 5
chr10_+_79852487 3.60 ENSMUST00000099501.10
Rho GTPase activating protein 45
chr8_-_4829519 3.50 ENSMUST00000022945.9
Shc SH2-domain binding protein 1
chr3_-_67371161 3.43 ENSMUST00000058981.3
latexin
chr18_+_50186349 3.42 ENSMUST00000148159.3
tumor necrosis factor, alpha-induced protein 8
chr6_+_116327853 3.34 ENSMUST00000140884.8
ENSMUST00000129170.8
membrane associated ring-CH-type finger 8
chr8_+_46338498 3.22 ENSMUST00000034053.7
PDZ and LIM domain 3
chr4_+_63477018 3.16 ENSMUST00000077709.11
transmembrane protein 268
chr7_+_127503251 3.16 ENSMUST00000071056.14
branched chain ketoacid dehydrogenase kinase
chr2_-_34645241 3.15 ENSMUST00000102800.9
GTPase activating protein and VPS9 domains 1
chr11_+_117673107 3.07 ENSMUST00000050874.14
ENSMUST00000106334.9
transmembrane channel-like gene family 8
chr9_+_48073296 3.05 ENSMUST00000216998.2
ENSMUST00000215780.2
neurexophilin and PC-esterase domain family, member 4
chr8_-_123278054 3.04 ENSMUST00000156333.9
ENSMUST00000067252.14
piezo-type mechanosensitive ion channel component 1
chr1_+_136395673 3.01 ENSMUST00000189413.7
ENSMUST00000047817.12
kinesin family member 14
chr9_-_62719208 2.92 ENSMUST00000034775.10
fem 1 homolog b
chr1_+_160898283 2.91 ENSMUST00000028035.14
ENSMUST00000111620.10
ENSMUST00000111618.8
centromere protein L
chr7_-_29979758 2.83 ENSMUST00000108190.8
WD repeat domain 62
chr1_-_181670599 2.83 ENSMUST00000193030.6
lamin B receptor
chr15_-_102112657 2.78 ENSMUST00000231030.2
ENSMUST00000230687.2
ENSMUST00000229514.2
ENSMUST00000229345.2
cysteine sulfinic acid decarboxylase
chr5_+_64250268 2.68 ENSMUST00000087324.7
phosphoglucomutase 2
chr9_-_45180433 2.67 ENSMUST00000176222.2
ENSMUST00000034594.16
interleukin 10 receptor, alpha
chr2_+_32253016 2.66 ENSMUST00000132028.8
ENSMUST00000136079.8
CDKN1A interacting zinc finger protein 1
chr8_+_27575611 2.65 ENSMUST00000178514.8
ENSMUST00000033876.14
adhesion G protein-coupled receptor A2
chr1_-_171061902 2.64 ENSMUST00000079957.12
Fc receptor, IgE, high affinity I, gamma polypeptide
chr15_-_100567412 2.63 ENSMUST00000183211.8
bridging integrator 2
chr7_+_97102411 2.63 ENSMUST00000121987.3
ENSMUST00000050732.14
ENSMUST00000205577.2
ENSMUST00000206279.2
potassium channel tetramerisation domain containing 14
chr19_-_7218512 2.53 ENSMUST00000025675.11
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr19_-_7218363 2.49 ENSMUST00000236769.2
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr5_+_30360246 2.48 ENSMUST00000026841.15
ENSMUST00000123980.8
ENSMUST00000114783.6
ENSMUST00000114786.8
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr18_+_23885390 2.45 ENSMUST00000170802.8
ENSMUST00000155708.8
ENSMUST00000118826.9
microtubule-associated protein, RP/EB family, member 2
chr17_-_71833752 2.40 ENSMUST00000232863.2
ENSMUST00000024851.10
NDC80 kinetochore complex component
chr10_-_128755127 2.38 ENSMUST00000149961.2
ENSMUST00000026406.14
retinol dehydrogenase 5
chr2_-_156833932 2.35 ENSMUST00000109558.2
ENSMUST00000069600.13
ENSMUST00000072298.13
N-myc downstream regulated gene 3
chr2_+_32253692 2.35 ENSMUST00000113331.8
ENSMUST00000113338.9
CDKN1A interacting zinc finger protein 1
chr3_+_95071617 2.33 ENSMUST00000168321.8
ENSMUST00000107217.6
ENSMUST00000202315.3
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr16_+_22710785 2.23 ENSMUST00000023583.7
ENSMUST00000232098.2
alpha-2-HS-glycoprotein
chr8_+_46338557 2.19 ENSMUST00000210422.2
PDZ and LIM domain 3
chr2_-_35351259 2.14 ENSMUST00000113001.9
ENSMUST00000113002.9
glycoprotein galactosyltransferase alpha 1, 3
chrX_+_164953444 2.10 ENSMUST00000130880.9
ENSMUST00000056410.11
ENSMUST00000096252.10
ENSMUST00000087169.11
gem nuclear organelle associated protein 8
chr18_-_35781422 2.09 ENSMUST00000237462.2
marginal zone B and B1 cell-specific protein 1
chrX_-_7814087 2.06 ENSMUST00000115642.8
ENSMUST00000033501.15
ENSMUST00000145675.8
histone deacetylase 6
chr11_+_117673198 2.01 ENSMUST00000117781.8
transmembrane channel-like gene family 8
chr2_+_32253204 1.99 ENSMUST00000048964.14
ENSMUST00000113332.8
CDKN1A interacting zinc finger protein 1
chr7_-_125090540 1.99 ENSMUST00000138616.3
NSE1 homolog, SMC5-SMC6 complex component
chr17_+_34812361 1.96 ENSMUST00000174532.2
pre B cell leukemia homeobox 2
chr16_+_57173456 1.94 ENSMUST00000159816.8
filamin A interacting protein 1-like
chr16_+_4704103 1.93 ENSMUST00000023159.10
ENSMUST00000070658.16
ENSMUST00000229038.2
mahogunin, ring finger 1
chrX_-_101295787 1.92 ENSMUST00000050551.10
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr4_-_56802266 1.92 ENSMUST00000030140.3
elongator complex protein 1
chrX_+_149829131 1.90 ENSMUST00000112685.8
FYVE, RhoGEF and PH domain containing 1
chrX_+_139857640 1.90 ENSMUST00000112971.2
autophagy related 4A, cysteine peptidase
chr16_-_18884431 1.89 ENSMUST00000200235.2
immunoglobulin lambda constant 3
chr3_-_81981946 1.83 ENSMUST00000029635.14
ENSMUST00000193597.2
guanylate cyclase 1, soluble, beta 1
chr16_+_4704166 1.83 ENSMUST00000230990.2
mahogunin, ring finger 1
chr15_-_100585789 1.81 ENSMUST00000023775.9
chymotrypsin-like elastase family, member 1
chr6_-_72357398 1.78 ENSMUST00000101285.10
ENSMUST00000074231.6
vesicle-associated membrane protein 5
chr2_+_24276616 1.77 ENSMUST00000166388.2
pleckstrin and Sec7 domain containing 4
chr9_-_107971640 1.77 ENSMUST00000081309.13
ENSMUST00000191985.2
acylpeptide hydrolase
chr13_+_56757389 1.74 ENSMUST00000045173.10
transforming growth factor, beta induced
chr19_+_45035942 1.74 ENSMUST00000237222.2
ENSMUST00000111954.11
sideroflexin 3
chr2_-_35351408 1.71 ENSMUST00000102794.8
glycoprotein galactosyltransferase alpha 1, 3
chr7_-_125090757 1.70 ENSMUST00000033006.14
NSE1 homolog, SMC5-SMC6 complex component
chr7_-_5016237 1.67 ENSMUST00000208944.2
Flt3 interacting zinc finger protein 1
chr5_-_110987441 1.66 ENSMUST00000145318.2
HscB iron-sulfur cluster co-chaperone
chr13_-_24945423 1.66 ENSMUST00000176890.8
ENSMUST00000175689.8
geminin
chr9_-_56151334 1.66 ENSMUST00000188142.7
pseudopodium-enriched atypical kinase 1
chr16_+_22713593 1.61 ENSMUST00000232674.2
alpha-2-HS-glycoprotein
chr8_+_105066924 1.60 ENSMUST00000212081.2
CKLF-like MARVEL transmembrane domain containing 3
chr19_+_45036037 1.57 ENSMUST00000062213.13
sideroflexin 3
chr4_+_149670889 1.56 ENSMUST00000105691.8
calsyntenin 1
chr7_-_19093383 1.55 ENSMUST00000047036.10
CD3E antigen, epsilon polypeptide associated protein
chrX_+_139857688 1.54 ENSMUST00000239541.1
autophagy related 4A, cysteine peptidase
chr10_+_52109707 1.52 ENSMUST00000069004.14
ENSMUST00000218582.2
discoidin, CUB and LCCL domain containing 1
chr5_-_30360113 1.51 ENSMUST00000156859.3
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
chrX_-_100312629 1.51 ENSMUST00000117736.2
predicted gene 20489
chr1_+_135764092 1.49 ENSMUST00000188028.7
ENSMUST00000178204.8
ENSMUST00000190451.7
ENSMUST00000189732.7
ENSMUST00000189355.7
troponin T2, cardiac
chr7_+_127836502 1.45 ENSMUST00000044660.6
armadillo repeat containing 5
chr8_+_104828253 1.45 ENSMUST00000034339.10
cadherin 5
chr2_+_29509704 1.42 ENSMUST00000095087.11
ENSMUST00000091146.12
ENSMUST00000102872.11
ENSMUST00000147755.10
Rap guanine nucleotide exchange factor (GEF) 1
chr5_-_113163339 1.42 ENSMUST00000197776.2
ENSMUST00000065167.9
G protein-coupled receptor kinase 3
chr1_-_192880260 1.42 ENSMUST00000161367.2
TRAF3 interacting protein 3
chrX_+_100317629 1.42 ENSMUST00000117706.8
mediator complex subunit 12
chr11_-_117673008 1.40 ENSMUST00000152304.3
transmembrane channel-like gene family 6
chr2_+_121337226 1.39 ENSMUST00000099473.10
ENSMUST00000110602.9
WD repeat domain 76
chr2_+_130266253 1.38 ENSMUST00000128994.8
ENSMUST00000028900.11
VSP16 CORVET/HOPS core subunit
chr9_+_98445757 1.38 ENSMUST00000035033.7
coatomer protein complex, subunit beta 2 (beta prime)
chr13_-_100753419 1.36 ENSMUST00000168772.2
ENSMUST00000163163.9
ENSMUST00000022137.14
MARVEL (membrane-associating) domain containing 2
chr11_-_121119864 1.36 ENSMUST00000137299.8
cytochrome b 245 chaperone 1
chr5_-_124327776 1.34 ENSMUST00000159677.8
phosphatidylinositol transfer protein, membrane-associated 2
chr8_+_75940572 1.32 ENSMUST00000139848.8
RASD family, member 2
chr11_-_100510992 1.32 ENSMUST00000014339.15
ENSMUST00000239490.2
ENSMUST00000239410.2
DnaJ heat shock protein family (Hsp40) member C7
chr3_+_89344006 1.28 ENSMUST00000038942.10
ENSMUST00000130858.8
ENSMUST00000146630.8
ENSMUST00000145753.2
pre B cell leukemia transcription factor interacting protein 1
chr5_+_115644727 1.26 ENSMUST00000067268.15
ENSMUST00000086523.7
ENSMUST00000212819.3
paxillin
chr6_+_83112793 1.26 ENSMUST00000065512.11
rhotekin
chr9_-_58220469 1.24 ENSMUST00000061799.10
lysyl oxidase-like 1
chr19_-_4927910 1.23 ENSMUST00000006626.5
actinin alpha 3
chr1_+_39940189 1.21 ENSMUST00000191761.6
ENSMUST00000193682.6
ENSMUST00000195860.6
ENSMUST00000195259.6
ENSMUST00000195636.6
ENSMUST00000192509.6
mitogen-activated protein kinase kinase kinase kinase 4
chr9_-_45895635 1.21 ENSMUST00000215427.2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr11_-_78642480 1.20 ENSMUST00000059468.6
cyclin Q
chr4_+_56802338 1.20 ENSMUST00000045368.12
actin binding transcription modulator
chr9_+_64024429 1.17 ENSMUST00000034969.14
lactase-like
chr19_-_24178000 1.16 ENSMUST00000233658.3
tight junction protein 2
chr7_+_43000765 1.15 ENSMUST00000012798.14
ENSMUST00000122423.8
sialic acid binding Ig-like lectin F
chr11_+_43365103 1.15 ENSMUST00000173002.8
ENSMUST00000057679.10
C1q and tumor necrosis factor related protein 2
chr8_-_112737952 1.15 ENSMUST00000034426.14
lysyl-tRNA synthetase
chr11_-_101877832 1.15 ENSMUST00000107173.9
ENSMUST00000107172.8
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
chr9_+_69902697 1.13 ENSMUST00000165389.8
BCL2/adenovirus E1B interacting protein 2
chr19_+_45036220 1.12 ENSMUST00000084493.8
sideroflexin 3
chr11_+_72580823 1.12 ENSMUST00000155998.2
ankyrin repeat and FYVE domain containing 1
chr16_+_20354225 1.11 ENSMUST00000090023.13
ENSMUST00000007216.9
ENSMUST00000232001.2
adaptor-related protein complex 2, mu 1 subunit
chr11_-_5787743 1.10 ENSMUST00000109837.8
polymerase (DNA directed), mu
chr7_+_140436870 1.09 ENSMUST00000026558.7
RIC8 guanine nucleotide exchange factor A
chr2_+_87696836 1.08 ENSMUST00000213308.3
olfactory receptor 1152
chr18_-_36648850 1.08 ENSMUST00000025363.7
heparin-binding EGF-like growth factor
chr8_+_4216556 1.08 ENSMUST00000239400.2
ENSMUST00000177053.8
ENSMUST00000176149.9
ENSMUST00000176072.9
ENSMUST00000176825.3
ecotropic viral integration site 5 like
chr7_+_122564859 1.07 ENSMUST00000148880.2
retinoblastoma binding protein 6, ubiquitin ligase
chr8_-_112737898 1.04 ENSMUST00000093120.13
ENSMUST00000164470.3
ENSMUST00000211990.2
lysyl-tRNA synthetase
chr10_+_17931459 1.04 ENSMUST00000154718.8
ENSMUST00000126390.8
ENSMUST00000164556.8
ENSMUST00000150029.8
RalBP1 associated Eps domain containing protein
chr8_-_123404811 1.03 ENSMUST00000006525.14
ENSMUST00000064674.13
CBFA2/RUNX1 translocation partner 3
chr2_+_158636727 1.02 ENSMUST00000029186.14
ENSMUST00000109478.9
ENSMUST00000156893.2
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr4_-_40239700 1.01 ENSMUST00000142055.2
DEAD/H box helicase 58
chr9_-_44646487 1.01 ENSMUST00000034611.15
pleckstrin homology like domain, family B, member 1
chr11_+_82782938 1.00 ENSMUST00000018988.6
fibronectin type III domain containing 8
chr8_-_94825556 0.99 ENSMUST00000034206.6
Bardet-Biedl syndrome 2 (human)
chr10_-_79936987 0.99 ENSMUST00000218630.2
strawberry notch 2
chr3_-_95214102 0.98 ENSMUST00000107183.8
ENSMUST00000164406.8
ENSMUST00000123365.2
annexin A9
chr4_-_58206596 0.96 ENSMUST00000042850.9
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chrX_-_7813792 0.95 ENSMUST00000133349.2
histone deacetylase 6
chr2_+_128540822 0.94 ENSMUST00000014505.5
MER proto-oncogene tyrosine kinase
chr7_+_43000838 0.93 ENSMUST00000206299.2
ENSMUST00000121494.2
sialic acid binding Ig-like lectin F
chr7_-_103778992 0.92 ENSMUST00000053743.6
ubiquilin 5
chr4_-_151129020 0.88 ENSMUST00000103204.11
period circadian clock 3
chr7_-_44542098 0.87 ENSMUST00000003049.8
mediator complex subunit 25
chr8_-_110292366 0.86 ENSMUST00000042601.9
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr15_-_102112159 0.86 ENSMUST00000229252.2
ENSMUST00000229770.2
cysteine sulfinic acid decarboxylase
chr13_-_113063890 0.85 ENSMUST00000022281.5
Mtr4 exosome RNA helicase
chr5_+_136112765 0.84 ENSMUST00000042135.14
RAS p21 protein activator 4
chr11_-_94440025 0.84 ENSMUST00000040487.4
radical S-adenosyl methionine domain containing 1
chr1_+_172168764 0.80 ENSMUST00000056136.4
potassium inwardly-rectifying channel, subfamily J, member 10
chr8_+_40876827 0.80 ENSMUST00000049389.11
ENSMUST00000128166.8
ENSMUST00000167766.2
zinc finger, DHHC domain containing 2
chr13_+_43938251 0.78 ENSMUST00000015540.4
CD83 antigen
chr7_-_109559671 0.78 ENSMUST00000080437.13
DENN/MADD domain containing 5A
chr4_-_130253703 0.77 ENSMUST00000134159.3
zinc finger, CCHC domain containing 17
chr17_+_36134450 0.76 ENSMUST00000172846.2
flotillin 1
chr6_+_49344673 0.76 ENSMUST00000060561.15
ENSMUST00000121903.2
ENSMUST00000134786.2
family with sequence similarity 221, member A
chr8_-_57003828 0.72 ENSMUST00000134162.8
ENSMUST00000140107.8
ENSMUST00000040330.15
ENSMUST00000135337.8
centrosomal protein 44
chr17_-_43854530 0.71 ENSMUST00000178772.3
ankyrin repeat domain 66
chr10_+_129153986 0.70 ENSMUST00000215503.2
olfactory receptor 780
chr13_-_100753181 0.70 ENSMUST00000225754.2
MARVEL (membrane-associating) domain containing 2
chr9_-_107971729 0.69 ENSMUST00000193254.6
acylpeptide hydrolase
chr11_-_100510423 0.69 ENSMUST00000137688.9
ENSMUST00000239389.2
ENSMUST00000155152.9
ENSMUST00000154972.9
ENSMUST00000239479.2
ENSMUST00000132886.3
DnaJ heat shock protein family (Hsp40) member C7
chr8_-_69541852 0.68 ENSMUST00000037478.13
ENSMUST00000148856.2
solute carrier family 18 (vesicular monoamine), member 1
chr7_-_109559593 0.68 ENSMUST00000106722.2
DENN/MADD domain containing 5A
chr19_-_5438685 0.67 ENSMUST00000044207.5
squamous cell carcinoma antigen recognized by T cells 1
chr7_+_92390811 0.66 ENSMUST00000032879.15
RAB30, member RAS oncogene family
chr18_+_74401322 0.66 ENSMUST00000224047.2
methyl-CpG binding domain protein 1
chr3_-_95214443 0.66 ENSMUST00000015846.9
annexin A9
chr11_+_49141410 0.65 ENSMUST00000129588.2
mannoside acetylglucosaminyltransferase 1
chr2_-_165129675 0.65 ENSMUST00000109299.8
ENSMUST00000109298.8
ENSMUST00000130393.2
ENSMUST00000017808.14
ENSMUST00000131409.2
ENSMUST00000156134.8
ENSMUST00000133961.8
solute carrier family 35, member C2
chr11_+_69886652 0.64 ENSMUST00000101526.9
PHD finger protein 23
chr17_+_15616464 0.61 ENSMUST00000055352.8
family with sequence similarity 120, member B
chr6_+_83011154 0.61 ENSMUST00000000707.9
ENSMUST00000101257.4
lysyl oxidase-like 3
chr11_-_32217547 0.58 ENSMUST00000109389.9
ENSMUST00000129010.2
ENSMUST00000020530.12
nitrogen permease regulator-like 3
chr11_+_117672902 0.58 ENSMUST00000127080.9
transmembrane channel-like gene family 8
chr11_+_69886603 0.58 ENSMUST00000018716.10
PHD finger protein 23
chr16_+_21023505 0.57 ENSMUST00000006112.7
Eph receptor B3
chr7_-_30855295 0.56 ENSMUST00000186723.3
GRAM domain containing 1A
chrX_-_99670174 0.54 ENSMUST00000015812.12
PDZ domain containing 11
chrX_-_99669507 0.54 ENSMUST00000059099.7
PDZ domain containing 11
chr11_-_109613040 0.53 ENSMUST00000020938.8
FAM20A, golgi associated secretory pathway pseudokinase
chr4_+_156110621 0.53 ENSMUST00000103173.10
ENSMUST00000040274.13
ENSMUST00000122001.3
tumor necrosis factor receptor superfamily, member 18
chr10_-_13350106 0.51 ENSMUST00000105545.12
phosphatase and actin regulator 2
chr11_+_49141339 0.51 ENSMUST00000101293.11
mannoside acetylglucosaminyltransferase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.4 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.1 8.5 GO:0090290 positive regulation of macrophage fusion(GO:0034241) positive regulation of osteoclast proliferation(GO:0090290)
1.8 5.3 GO:0031104 dendrite regeneration(GO:0031104)
1.7 7.0 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
1.7 18.7 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
1.2 19.9 GO:0001542 ovulation from ovarian follicle(GO:0001542)
1.2 14.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
1.2 4.8 GO:0042710 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) membrane disruption in other organism(GO:0051673) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
1.0 6.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.0 3.0 GO:0021693 cerebellar Purkinje cell layer structural organization(GO:0021693)
1.0 3.8 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.9 4.5 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.8 2.5 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.7 2.2 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.7 2.9 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.7 3.6 GO:0042412 taurine biosynthetic process(GO:0042412)
0.7 4.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.7 2.6 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.6 3.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.6 5.3 GO:0015671 oxygen transport(GO:0015671)
0.6 10.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.5 3.4 GO:0051697 protein delipidation(GO:0051697)
0.4 2.7 GO:0019388 galactose catabolic process(GO:0019388)
0.4 2.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.4 1.2 GO:0014862 regulation of the force of skeletal muscle contraction(GO:0014728) regulation of skeletal muscle contraction by chemo-mechanical energy conversion(GO:0014862)
0.4 1.9 GO:0071104 response to interleukin-9(GO:0071104)
0.4 5.6 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.4 1.5 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.4 1.1 GO:0051542 elastin biosynthetic process(GO:0051542)
0.3 8.8 GO:0042730 fibrinolysis(GO:0042730)
0.3 2.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 1.0 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.3 0.9 GO:0036034 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.3 1.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
0.3 3.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.3 2.4 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.3 1.8 GO:0060309 elastin catabolic process(GO:0060309)
0.2 1.0 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.2 6.0 GO:2000193 positive regulation of fatty acid transport(GO:2000193)
0.2 1.7 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 1.4 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 0.8 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) regulation of resting membrane potential(GO:0060075)
0.2 7.0 GO:0097320 membrane tubulation(GO:0097320)
0.2 5.7 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.2 0.2 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.2 5.8 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.2 1.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.2 0.9 GO:0097350 neutrophil clearance(GO:0097350)
0.2 1.1 GO:0032439 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.2 1.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.2 1.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 5.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 1.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 0.3 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 0.6 GO:0015786 UDP-glucose transport(GO:0015786)
0.2 1.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 1.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 3.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.2 0.8 GO:0009597 detection of virus(GO:0009597)
0.1 1.0 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 1.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.4 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.1 3.8 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 3.7 GO:0006301 postreplication repair(GO:0006301)
0.1 0.8 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 1.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.5 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 2.4 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.6 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 2.6 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.7 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.7 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 0.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 1.1 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.8 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 1.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 1.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.0 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 1.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 1.1 GO:0070586 cell-cell adhesion involved in gastrulation(GO:0070586)
0.1 0.5 GO:0098735 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.1 2.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 4.2 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.1 1.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 2.1 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.1 2.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 1.4 GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 3.4 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 1.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.3 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 1.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 1.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 4.2 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 1.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.5 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 1.8 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.5 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.7 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.2 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.8 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 1.7 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.9 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187) circadian sleep/wake cycle, sleep(GO:0050802)
0.0 3.5 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 1.5 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.6 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.0 0.6 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0070255 regulation of mucus secretion(GO:0070255)
0.0 1.2 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 1.9 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.6 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.5 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 3.8 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026) peptidyl-lysine dimethylation(GO:0018027)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 4.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.1 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.7 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 1.1 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 1.1 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 1.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 18.7 GO:0070442 integrin alphaIIb-beta3 complex(GO:0070442)
0.9 2.6 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.8 4.8 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.7 5.3 GO:0005833 hemoglobin complex(GO:0005833)
0.6 2.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.5 3.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.4 3.7 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 8.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.3 5.0 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 4.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 2.1 GO:0061689 paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.2 1.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 7.0 GO:0001891 phagocytic cup(GO:0001891)
0.2 5.3 GO:0005682 U5 snRNP(GO:0005682)
0.2 2.1 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.2 1.4 GO:0033263 CORVET complex(GO:0033263)
0.1 2.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 2.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 2.8 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 6.7 GO:0015030 Cajal body(GO:0015030)
0.1 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.5 GO:0001652 granular component(GO:0001652)
0.1 1.0 GO:0034464 BBSome(GO:0034464)
0.1 1.0 GO:0045180 basal cortex(GO:0045180)
0.1 3.0 GO:0051233 spindle midzone(GO:0051233)
0.1 1.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 2.4 GO:0035371 microtubule plus-end(GO:0035371)
0.1 3.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 7.3 GO:0005604 basement membrane(GO:0005604)
0.0 1.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 6.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.2 GO:0016235 aggresome(GO:0016235)
0.0 0.8 GO:0097449 astrocyte projection(GO:0097449)
0.0 1.5 GO:0030904 retromer complex(GO:0030904)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 3.1 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 11.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 1.2 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.2 GO:0005921 gap junction(GO:0005921)
0.0 4.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.1 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 12.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.7 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 12.0 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 2.8 GO:0001726 ruffle(GO:0001726)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 3.6 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 3.9 GO:0005769 early endosome(GO:0005769)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 1.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0061702 inflammasome complex(GO:0061702)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 19.9 GO:0004566 beta-glucuronidase activity(GO:0004566)
1.3 4.0 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
1.3 5.3 GO:0031721 hemoglobin alpha binding(GO:0031721)
1.2 6.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.9 4.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.6 3.8 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.6 3.8 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
0.6 5.0 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.5 10.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.5 2.6 GO:0019767 IgE receptor activity(GO:0019767)
0.5 3.6 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.5 2.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.5 4.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.5 4.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 2.7 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.4 2.7 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.3 2.9 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3 1.3 GO:0051435 BH4 domain binding(GO:0051435)
0.3 1.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.3 1.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.3 15.9 GO:0050699 WW domain binding(GO:0050699)
0.3 2.8 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 1.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 1.5 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.2 7.4 GO:0070412 R-SMAD binding(GO:0070412)
0.2 1.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 1.2 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 0.7 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.2 0.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2 4.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 1.9 GO:0050693 LBD domain binding(GO:0050693)
0.2 4.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 3.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 7.2 GO:0030332 cyclin binding(GO:0030332)
0.1 2.5 GO:0008242 omega peptidase activity(GO:0008242)
0.1 1.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 2.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 3.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 3.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 2.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 2.9 GO:0005123 death receptor binding(GO:0005123)
0.1 0.5 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.7 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.1 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.1 8.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 3.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 2.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.8 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 3.5 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.4 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 2.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 5.4 GO:0005179 hormone activity(GO:0005179)
0.0 1.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 2.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.9 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 2.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 5.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 2.0 GO:0031072 heat shock protein binding(GO:0031072)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 19.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 3.8 PID BMP PATHWAY BMP receptor signaling
0.1 5.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 2.4 PID AURORA B PATHWAY Aurora B signaling
0.0 3.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.1 PID ARF 3PATHWAY Arf1 pathway
0.0 2.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 2.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 5.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 6.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 11.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.7 10.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 6.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.7 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 6.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 4.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 4.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 5.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 2.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline