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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nr3c2

Z-value: 0.38

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Transcription factors associated with Nr3c2

Gene Symbol Gene ID Gene Info
Nr3c2
ENSMUSG00000031618.14 Nr3c2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr3c2mm39_v1_chr8_+_77626400_77626456-0.372.8e-02Click!

Activity profile of Nr3c2 motif

Sorted Z-values of Nr3c2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr3c2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr8_+_94905710 2.34 ENSMUST00000034215.8
ENSMUST00000212291.2
ENSMUST00000211807.2
Mt1
metallothionein 1
chr8_+_71858647 0.89 ENSMUST00000119976.8
ENSMUST00000120725.2
Ankle1
ankyrin repeat and LEM domain containing 1
chr4_-_149221998 0.84 ENSMUST00000176124.8
ENSMUST00000177408.2
ENSMUST00000105695.2
Cenps
centromere protein S
chr10_-_117118226 0.76 ENSMUST00000092163.9
Lyz2
lysozyme 2
chr11_+_68989763 0.72 ENSMUST00000021271.14
Per1
period circadian clock 1
chr4_-_149222057 0.70 ENSMUST00000030813.10
Cenps
centromere protein S
chr9_+_123195986 0.63 ENSMUST00000038863.9
ENSMUST00000216843.2
Lars2
leucyl-tRNA synthetase, mitochondrial
chr16_+_38167352 0.55 ENSMUST00000050273.9
ENSMUST00000120495.2
ENSMUST00000119704.2
Cox17
Gm21987
cytochrome c oxidase assembly protein 17, copper chaperone
predicted gene 21987
chr5_+_31855009 0.49 ENSMUST00000201352.4
ENSMUST00000202815.4
Babam2
BRISC and BRCA1 A complex member 2
chr5_-_31854942 0.45 ENSMUST00000031018.10
Rbks
ribokinase
chr15_-_81931783 0.36 ENSMUST00000080622.9
Snu13
SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
chr8_-_25730878 0.34 ENSMUST00000210488.2
ENSMUST00000210933.2
Tacc1
transforming, acidic coiled-coil containing protein 1
chr11_+_96822213 0.33 ENSMUST00000107633.2
Prr15l
proline rich 15-like
chr5_+_123280250 0.30 ENSMUST00000174836.8
ENSMUST00000163030.9
Setd1b
SET domain containing 1B
chr16_+_16844217 0.27 ENSMUST00000232067.2
Mapk1
mitogen-activated protein kinase 1
chr7_-_141934524 0.24 ENSMUST00000209263.2
Gm49369
predicted gene, 49369
chr11_-_75345482 0.23 ENSMUST00000173320.8
Wdr81
WD repeat domain 81
chr4_-_9643636 0.16 ENSMUST00000108333.8
ENSMUST00000108334.8
ENSMUST00000108335.8
ENSMUST00000152526.8
ENSMUST00000103004.10
Asph
aspartate-beta-hydroxylase
chr6_-_69220672 0.16 ENSMUST00000196201.2
Igkv4-71
immunoglobulin kappa chain variable 4-71
chr6_+_136495784 0.15 ENSMUST00000032335.13
ENSMUST00000185724.7
Atf7ip
activating transcription factor 7 interacting protein
chr5_-_135494775 0.13 ENSMUST00000212301.2
Hip1
huntingtin interacting protein 1
chr10_-_14593935 0.13 ENSMUST00000020016.5
Gje1
gap junction protein, epsilon 1
chr6_-_69584812 0.12 ENSMUST00000103359.3
Igkv4-55
immunoglobulin kappa variable 4-55
chr6_+_136495818 0.11 ENSMUST00000186577.7
Atf7ip
activating transcription factor 7 interacting protein
chr15_-_85705935 0.10 ENSMUST00000064370.6
Pkdrej
polycystin (PKD) family receptor for egg jelly
chr6_+_52691204 0.09 ENSMUST00000138040.8
ENSMUST00000129660.2
Tax1bp1
Tax1 (human T cell leukemia virus type I) binding protein 1
chr6_-_69020489 0.09 ENSMUST00000103342.4
Igkv4-79
immunoglobulin kappa variable 4-79
chr6_+_34840151 0.08 ENSMUST00000202010.2
Tmem140
transmembrane protein 140
chr11_-_71092282 0.07 ENSMUST00000108515.9
Nlrp1b
NLR family, pyrin domain containing 1B
chr1_-_74974707 0.07 ENSMUST00000094844.4
Cfap65
cilia and flagella associated protein 65
chr11_-_71092124 0.07 ENSMUST00000108514.10
Nlrp1b
NLR family, pyrin domain containing 1B
chr9_-_75504926 0.07 ENSMUST00000164100.2
Tmod2
tropomodulin 2
chr6_-_69204417 0.07 ENSMUST00000103346.3
Igkv4-72
immunoglobulin kappa chain variable 4-72
chr6_-_69377328 0.07 ENSMUST00000198345.2
Igkv4-62
immunoglobulin kappa variable 4-62
chr11_+_50905063 0.06 ENSMUST00000217480.2
ENSMUST00000215409.2
Olfr54
olfactory receptor 54
chr6_-_69037208 0.06 ENSMUST00000103343.4
Igkv4-78
immunoglobulin kappa variable 4-78
chr17_+_23562715 0.06 ENSMUST00000168175.3
ENSMUST00000234796.2
Vmn2r115
vomeronasal 2, receptor 115
chr8_-_95328348 0.05 ENSMUST00000212547.2
ENSMUST00000212507.2
ENSMUST00000034226.8
Psme3ip1
proteasome activator subunit 3 interacting protein 1
chr14_+_35816874 0.05 ENSMUST00000226305.2
4930474N05Rik
RIKEN cDNA 4930474N05 gene
chr6_-_69609162 0.05 ENSMUST00000199437.2
Igkv4-54
immunoglobulin kappa chain variable 4-54
chr5_+_112436599 0.05 ENSMUST00000151947.3
Tpst2
protein-tyrosine sulfotransferase 2
chr1_+_173959083 0.05 ENSMUST00000214751.2
Olfr424
olfactory receptor 424
chr17_-_22792463 0.05 ENSMUST00000092491.7
ENSMUST00000234223.2
ENSMUST00000234296.2
ENSMUST00000234027.2
Vmn2r111
vomeronasal 2, receptor 111
chr14_+_54000594 0.04 ENSMUST00000103589.6
Trav14-3
T cell receptor alpha variable 14-3
chr10_+_26698556 0.03 ENSMUST00000135866.2
Arhgap18
Rho GTPase activating protein 18
chr10_+_128061699 0.03 ENSMUST00000026455.8
Mip
major intrinsic protein of lens fiber
chr7_+_106630381 0.03 ENSMUST00000213623.2
Olfr713
olfactory receptor 713
chr11_+_98277276 0.03 ENSMUST00000041301.8
Pnmt
phenylethanolamine-N-methyltransferase
chr9_+_99494550 0.03 ENSMUST00000042553.8
A4gnt
alpha-1,4-N-acetylglucosaminyltransferase
chr7_+_118199375 0.02 ENSMUST00000121744.9
Tmc5
transmembrane channel-like gene family 5
chr6_-_6882068 0.02 ENSMUST00000142635.2
ENSMUST00000052609.9
Dlx5
distal-less homeobox 5
chr17_+_22819932 0.02 ENSMUST00000097381.5
ENSMUST00000234882.2
Vmn2r112
vomeronasal 2, receptor 112
chr17_-_23531402 0.01 ENSMUST00000168033.3
Vmn2r114
vomeronasal 2, receptor 114
chr13_-_120374288 0.01 ENSMUST00000179502.2
Gm21761
predicted gene, 21761
chr13_+_120616163 0.01 ENSMUST00000179071.2
Gm20767
predicted gene, 20767
chr6_-_126512375 0.01 ENSMUST00000060972.5
Kcna5
potassium voltage-gated channel, shaker-related subfamily, member 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.5 GO:1904959 regulation of cytochrome-c oxidase activity(GO:1904959)
0.3 2.3 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.2 0.6 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.1 0.9 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.1 0.7 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.4 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 1.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.5 GO:0070552 BRISC complex(GO:0070552)
0.0 0.9 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.4 GO:0031428 dense fibrillar component(GO:0001651) box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.1 0.4 GO:0030622 U4atac snRNA binding(GO:0030622)
0.1 0.8 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.5 GO:0016531 copper chaperone activity(GO:0016531)
0.0 2.3 GO:0005507 copper ion binding(GO:0005507)
0.0 0.0 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 1.6 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression