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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Nr6a1

Z-value: 1.63

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Transcription factors associated with Nr6a1

Gene Symbol Gene ID Gene Info
Nr6a1
ENSMUSG00000063972.14 Nr6a1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr6a1mm39_v1_chr2_-_38816229_388163660.212.2e-01Click!

Activity profile of Nr6a1 motif

Sorted Z-values of Nr6a1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr6a1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_+_22769844 10.87 ENSMUST00000232422.2
Hrg
histidine-rich glycoprotein
chr16_+_22769822 10.80 ENSMUST00000023590.9
Hrg
histidine-rich glycoprotein
chr17_-_57535003 7.85 ENSMUST00000177046.2
ENSMUST00000024988.15
C3
complement component 3
chr7_-_105249308 7.55 ENSMUST00000210531.2
ENSMUST00000033185.10
Hpx
hemopexin
chr6_+_42222841 6.50 ENSMUST00000031897.8
Gstk1
glutathione S-transferase kappa 1
chr1_+_160806241 6.23 ENSMUST00000195760.2
Serpinc1
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr1_+_160806194 6.20 ENSMUST00000064725.11
ENSMUST00000191936.2
Serpinc1
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr3_+_107137924 5.84 ENSMUST00000179399.3
A630076J17Rik
RIKEN cDNA A630076J17 gene
chr9_-_118986123 5.49 ENSMUST00000010795.5
Acaa1b
acetyl-Coenzyme A acyltransferase 1B
chr6_+_90310252 5.08 ENSMUST00000046128.12
ENSMUST00000164761.6
Uroc1
urocanase domain containing 1
chr15_+_31572251 3.93 ENSMUST00000161088.3
Cmbl
carboxymethylenebutenolidase-like (Pseudomonas)
chr2_+_24944367 3.89 ENSMUST00000100334.11
ENSMUST00000152122.8
ENSMUST00000116574.10
ENSMUST00000006646.15
Nsmf
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr2_+_24944407 3.82 ENSMUST00000102931.11
ENSMUST00000074422.14
ENSMUST00000132172.8
ENSMUST00000114388.8
Nsmf
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr14_+_79086665 3.80 ENSMUST00000227255.2
Vwa8
von Willebrand factor A domain containing 8
chr14_+_79086492 3.64 ENSMUST00000040990.7
Vwa8
von Willebrand factor A domain containing 8
chr5_-_108822619 3.08 ENSMUST00000119270.2
ENSMUST00000163328.8
ENSMUST00000136227.2
Slc26a1
solute carrier family 26 (sulfate transporter), member 1
chr11_-_60702081 3.06 ENSMUST00000018744.15
Shmt1
serine hydroxymethyltransferase 1 (soluble)
chr6_-_124613044 2.90 ENSMUST00000068797.3
ENSMUST00000218020.2
C1s2
complement component 1, s subcomponent 2
chr12_-_28673259 2.72 ENSMUST00000220836.2
Colec11
collectin sub-family member 11
chr12_-_28673311 2.64 ENSMUST00000036136.9
Colec11
collectin sub-family member 11
chr1_+_131898325 2.31 ENSMUST00000027695.8
Slc45a3
solute carrier family 45, member 3
chr4_-_82423511 2.25 ENSMUST00000050872.15
ENSMUST00000064770.9
Nfib
nuclear factor I/B
chr7_+_44890497 2.24 ENSMUST00000213347.2
Slc6a16
solute carrier family 6, member 16
chr4_+_138161958 2.17 ENSMUST00000044058.11
ENSMUST00000105813.8
ENSMUST00000105815.2
Mul1
mitochondrial ubiquitin ligase activator of NFKB 1
chr10_+_21854540 2.11 ENSMUST00000142174.8
ENSMUST00000164659.8
Sgk1
serum/glucocorticoid regulated kinase 1
chr9_+_122634589 2.09 ENSMUST00000052740.14
Tcaim
T cell activation inhibitor, mitochondrial
chr17_-_26004507 1.86 ENSMUST00000140738.8
ENSMUST00000145053.2
ENSMUST00000138759.8
ENSMUST00000133071.8
ENSMUST00000077938.10
Haghl
hydroxyacylglutathione hydrolase-like
chr6_-_57512355 1.82 ENSMUST00000042766.6
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr5_-_36641456 1.70 ENSMUST00000119916.2
ENSMUST00000031097.8
Tada2b
transcriptional adaptor 2B
chr11_-_100661762 1.70 ENSMUST00000139341.2
ENSMUST00000017891.14
Ghdc
GH3 domain containing
chr9_-_50515089 1.69 ENSMUST00000000175.6
Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
chr2_+_127267069 1.68 ENSMUST00000062211.4
Gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr2_+_32496957 1.68 ENSMUST00000113290.8
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr13_-_25204272 1.52 ENSMUST00000021772.4
Mrs2
MRS2 magnesium transporter
chr4_-_82423985 1.51 ENSMUST00000107245.9
ENSMUST00000107246.2
Nfib
nuclear factor I/B
chr10_-_68377672 1.49 ENSMUST00000020103.9
Cabcoco1
ciliary associated calcium binding coiled-coil 1
chr13_+_31740117 1.47 ENSMUST00000042118.11
Foxq1
forkhead box Q1
chr4_-_45530330 1.45 ENSMUST00000061986.12
Shb
src homology 2 domain-containing transforming protein B
chr2_+_32496990 1.44 ENSMUST00000095045.9
ENSMUST00000095044.10
ENSMUST00000126636.8
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr5_+_8943943 1.39 ENSMUST00000196067.2
Abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr17_-_26004298 1.36 ENSMUST00000150324.8
Haghl
hydroxyacylglutathione hydrolase-like
chr8_-_110419867 1.30 ENSMUST00000034164.6
Ist1
increased sodium tolerance 1 homolog (yeast)
chr4_-_82423944 1.29 ENSMUST00000107248.8
ENSMUST00000107247.8
Nfib
nuclear factor I/B
chr17_-_46956054 1.28 ENSMUST00000003642.7
Klc4
kinesin light chain 4
chr18_-_6135888 1.19 ENSMUST00000182383.8
ENSMUST00000062584.14
ENSMUST00000077128.13
ENSMUST00000182038.2
ENSMUST00000182213.8
ENSMUST00000182559.8
Arhgap12
Rho GTPase activating protein 12
chr5_-_137609691 1.13 ENSMUST00000031731.14
Pcolce
procollagen C-endopeptidase enhancer protein
chr5_-_137609634 0.94 ENSMUST00000054564.13
Pcolce
procollagen C-endopeptidase enhancer protein
chr5_-_137608886 0.94 ENSMUST00000142675.8
Pcolce
procollagen C-endopeptidase enhancer protein
chr7_-_132178101 0.90 ENSMUST00000084500.8
Oat
ornithine aminotransferase
chr12_-_114752425 0.87 ENSMUST00000103510.2
Ighv1-26
immunoglobulin heavy variable 1-26
chr18_+_65020760 0.83 ENSMUST00000235343.2
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr11_-_76654375 0.82 ENSMUST00000010536.9
Gosr1
golgi SNAP receptor complex member 1
chr17_+_73225292 0.75 ENSMUST00000024857.14
Lbh
limb-bud and heart
chr11_+_83742961 0.75 ENSMUST00000146786.8
Hnf1b
HNF1 homeobox B
chr18_+_65020910 0.74 ENSMUST00000236736.2
ENSMUST00000235743.2
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr12_-_115884332 0.73 ENSMUST00000103548.3
Ighv1-81
immunoglobulin heavy variable 1-81
chr18_+_65020885 0.70 ENSMUST00000236209.2
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr2_+_179713586 0.69 ENSMUST00000108901.8
Mtg2
mitochondrial ribosome associated GTPase 2
chr12_+_44268134 0.68 ENSMUST00000122902.8
Pnpla8
patatin-like phospholipase domain containing 8
chr12_-_115916604 0.65 ENSMUST00000196991.2
Ighv1-82
immunoglobulin heavy variable 1-82
chr9_+_53212871 0.63 ENSMUST00000051014.2
Exph5
exophilin 5
chr9_-_121668527 0.62 ENSMUST00000135986.9
Ccdc13
coiled-coil domain containing 13
chr12_-_114547622 0.61 ENSMUST00000193893.6
ENSMUST00000103498.3
Ighv1-9
immunoglobulin heavy variable V1-9
chrX_-_7884688 0.55 ENSMUST00000033503.3
Glod5
glyoxalase domain containing 5
chr19_+_46695889 0.53 ENSMUST00000003655.9
As3mt
arsenite methyltransferase
chr5_+_36641922 0.51 ENSMUST00000060100.3
Ccdc96
coiled-coil domain containing 96
chr5_+_137015873 0.41 ENSMUST00000004968.11
Plod3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr14_+_76725876 0.41 ENSMUST00000101618.9
Tsc22d1
TSC22 domain family, member 1
chr12_-_114672701 0.39 ENSMUST00000103505.3
ENSMUST00000193855.2
Ighv1-19
immunoglobulin heavy variable V1-19
chr6_+_21985902 0.38 ENSMUST00000115383.9
Cped1
cadherin-like and PC-esterase domain containing 1
chr9_+_45311000 0.37 ENSMUST00000216289.2
Fxyd2
FXYD domain-containing ion transport regulator 2
chr5_+_92524813 0.35 ENSMUST00000120781.8
Art3
ADP-ribosyltransferase 3
chr12_-_114646685 0.33 ENSMUST00000194350.6
ENSMUST00000103504.3
Ighv1-18
immunoglobulin heavy variable V1-18
chr5_+_30437579 0.33 ENSMUST00000145167.9
Selenoi
selenoprotein I
chr12_-_113896002 0.32 ENSMUST00000103463.3
Ighv14-1
immunoglobulin heavy variable 14-1
chr5_-_137015683 0.30 ENSMUST00000034953.14
ENSMUST00000085941.12
Znhit1
zinc finger, HIT domain containing 1
chr12_-_114878652 0.26 ENSMUST00000103515.2
Ighv1-39
immunoglobulin heavy variable 1-39
chr18_+_65158873 0.24 ENSMUST00000226058.2
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr16_+_10297923 0.21 ENSMUST00000230395.2
Ciita
class II transactivator
chr5_+_129802127 0.21 ENSMUST00000086046.10
ENSMUST00000186265.6
Nipsnap2
nipsnap homolog 2
chr13_+_113931038 0.20 ENSMUST00000091201.7
Arl15
ADP-ribosylation factor-like 15
chr16_+_11140779 0.18 ENSMUST00000115814.4
Snx29
sorting nexin 29
chr10_+_23846604 0.16 ENSMUST00000092659.4
Taar5
trace amine-associated receptor 5
chr1_+_151304293 0.16 ENSMUST00000065625.12
Trmt1l
tRNA methyltransferase 1 like
chr7_+_16678568 0.16 ENSMUST00000094807.6
Pnmal2
PNMA-like 2
chr19_+_47843461 0.15 ENSMUST00000237121.2
Gsto1
glutathione S-transferase omega 1
chr13_+_25239947 0.13 ENSMUST00000036932.15
Dcdc2a
doublecortin domain containing 2a
chr15_-_98063441 0.12 ENSMUST00000123922.2
Asb8
ankyrin repeat and SOCS box-containing 8
chr2_+_157266175 0.09 ENSMUST00000029175.14
ENSMUST00000092576.11
Src
Rous sarcoma oncogene
chr1_+_171156942 0.08 ENSMUST00000111299.8
ENSMUST00000064950.11
Dedd
death effector domain-containing
chr14_+_58310143 0.08 ENSMUST00000022545.14
Fgf9
fibroblast growth factor 9
chr12_-_71183371 0.07 ENSMUST00000221367.2
ENSMUST00000220482.2
ENSMUST00000221892.2
ENSMUST00000221178.2
ENSMUST00000221559.2
ENSMUST00000166120.9
ENSMUST00000021486.10
ENSMUST00000221797.2
ENSMUST00000221815.2
Timm9
translocase of inner mitochondrial membrane 9
chr1_+_171156568 0.05 ENSMUST00000111300.8
Dedd
death effector domain-containing
chr15_+_99936516 0.04 ENSMUST00000100203.10
Dip2b
disco interacting protein 2 homolog B
chr5_-_123711098 0.03 ENSMUST00000031388.13
Vps33a
VPS33A CORVET/HOPS core subunit
chr12_+_78240999 0.02 ENSMUST00000211288.3
Gm6657
predicted gene 6657
chr12_-_114579763 0.02 ENSMUST00000103500.2
Ighv1-12
immunoglobulin heavy variable V1-12

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.7 GO:0097037 heme export(GO:0097037)
2.0 7.9 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.9 7.6 GO:0015886 heme transport(GO:0015886)
1.6 12.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
1.3 7.7 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
1.3 5.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.0 3.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
1.0 5.1 GO:0006548 histidine catabolic process(GO:0006548)
0.6 2.3 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.5 1.4 GO:1903412 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
0.4 2.2 GO:1904925 negative regulation of mitochondrial fusion(GO:0010637) negative regulation of defense response to virus by host(GO:0050689) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.3 3.1 GO:0019532 oxalate transport(GO:0019532)
0.3 1.7 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.3 1.3 GO:0009838 abscission(GO:0009838)
0.3 3.2 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 3.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 0.7 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.2 2.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 2.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 0.7 GO:0035565 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.2 1.7 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 1.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 2.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.9 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.8 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.1 0.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 1.5 GO:0015693 magnesium ion transport(GO:0015693)
0.1 6.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.2 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.0 0.8 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 1.7 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.5 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.7 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.5 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.2 GO:0045345 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 3.0 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 1.2 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.7 GO:0061474 phagolysosome membrane(GO:0061474)
0.4 1.7 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 5.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 7.7 GO:0097440 apical dendrite(GO:0097440)
0.1 27.7 GO:0072562 blood microparticle(GO:0072562)
0.1 1.7 GO:0030914 STAGA complex(GO:0030914)
0.1 1.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.3 GO:0090543 Flemming body(GO:0090543)
0.0 5.4 GO:0005581 collagen trimer(GO:0005581)
0.0 8.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.8 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.6 GO:0015232 heme transporter activity(GO:0015232)
1.0 3.1 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372)
0.6 2.3 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.6 1.7 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.4 3.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.4 5.5 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.3 6.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.3 2.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 1.4 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.2 33.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 5.4 GO:0005537 mannose binding(GO:0005537)
0.2 1.7 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 2.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 5.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.3 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 1.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 2.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 5.1 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 7.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 7.9 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 3.0 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.9 GO:0008483 transaminase activity(GO:0008483)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0045174 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 6.5 GO:0016887 ATPase activity(GO:0016887)
0.0 1.3 GO:0003777 microtubule motor activity(GO:0003777)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 12.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 21.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 5.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 12.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.1 PID INSULIN PATHWAY Insulin Pathway
0.0 3.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 12.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.6 7.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 5.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 21.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 3.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME KINESINS Genes involved in Kinesins
0.0 1.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 6.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development