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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Onecut2_Onecut3

Z-value: 0.92

Motif logo

Transcription factors associated with Onecut2_Onecut3

Gene Symbol Gene ID Gene Info
ENSMUSG00000045991.20 Onecut2
ENSMUSG00000045518.9 Onecut3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Onecut3mm39_v1_chr10_+_80330669_80330714-0.438.3e-03Click!
Onecut2mm39_v1_chr18_+_64473091_644731140.363.1e-02Click!

Activity profile of Onecut2_Onecut3 motif

Sorted Z-values of Onecut2_Onecut3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Onecut2_Onecut3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_61972348 4.79 ENSMUST00000074018.4
major urinary protein 20
chr9_-_86577940 4.75 ENSMUST00000034989.15
malic enzyme 1, NADP(+)-dependent, cytosolic
chr6_-_128503666 4.45 ENSMUST00000143664.2
ENSMUST00000112132.8
PZP, alpha-2-macroglobulin like
chr3_-_81883509 4.37 ENSMUST00000029645.14
ENSMUST00000193879.2
tryptophan 2,3-dioxygenase
chr15_+_10224052 4.36 ENSMUST00000128450.8
ENSMUST00000148257.8
ENSMUST00000128921.8
prolactin receptor
chr3_+_20011251 2.86 ENSMUST00000108328.8
ceruloplasmin
chr3_+_20011201 2.73 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
ceruloplasmin
chr3_+_20011405 2.46 ENSMUST00000108325.9
ceruloplasmin
chr16_-_10360893 2.22 ENSMUST00000184863.8
ENSMUST00000038281.6
dexamethasone-induced transcript
chr7_+_119360141 2.21 ENSMUST00000106528.8
ENSMUST00000106527.8
ENSMUST00000063770.10
ENSMUST00000106529.8
acyl-CoA synthetase medium-chain family member 3
chr6_-_21852508 2.07 ENSMUST00000031678.10
tetraspanin 12
chr7_+_43856724 2.06 ENSMUST00000077354.5
kallikrein 1-related pepidase b4
chr10_+_128089965 1.88 ENSMUST00000060782.5
ENSMUST00000218722.2
apolipoprotein N
chr1_-_180083859 1.80 ENSMUST00000111108.10
presenilin 2
chr1_+_171041583 1.65 ENSMUST00000111328.8
nuclear receptor subfamily 1, group I, member 3
chr7_+_51537645 1.62 ENSMUST00000208711.2
growth arrest specific 2
chr1_+_171041539 1.58 ENSMUST00000005820.11
ENSMUST00000075469.12
ENSMUST00000155126.8
nuclear receptor subfamily 1, group I, member 3
chr5_-_87288177 1.46 ENSMUST00000067790.7
UDP glucuronosyltransferase 2 family, polypeptide B5
chr15_-_89361571 1.41 ENSMUST00000165199.8
arylsulfatase A
chr11_+_78389913 1.40 ENSMUST00000017488.5
vitronectin
chr6_-_85879510 1.32 ENSMUST00000159755.8
N-acetyltransferase 8 (GCN5-related) family member 4
chr7_-_27010068 1.27 ENSMUST00000125455.2
latent transforming growth factor beta binding protein 4
chr19_-_30152814 1.26 ENSMUST00000025778.9
glycine decarboxylase
chr15_+_54975713 1.26 ENSMUST00000096433.10
DEP domain containing MTOR-interacting protein
chr9_+_55234197 1.09 ENSMUST00000085754.10
ENSMUST00000034862.5
transmembrane protein 266
chr14_-_4488167 1.05 ENSMUST00000022304.12
thyroid hormone receptor beta
chr1_+_88030951 1.02 ENSMUST00000113135.6
ENSMUST00000113138.8
UDP glucuronosyltransferase 1 family, polypeptide A7C
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr8_-_118398264 1.01 ENSMUST00000037955.14
short chain dehydrogenase/reductase family 42E, member 1
chr1_+_167426019 0.99 ENSMUST00000111386.8
ENSMUST00000111384.8
retinoid X receptor gamma
chr9_-_51874846 0.98 ENSMUST00000034552.8
ENSMUST00000214013.2
ferredoxin 1
chr1_+_172525613 0.98 ENSMUST00000038495.5
C-reactive protein, pentraxin-related
chr17_-_35081129 0.93 ENSMUST00000154526.8
complement factor B
chr17_-_35081456 0.92 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr8_-_85500010 0.92 ENSMUST00000109764.8
nuclear factor I/X
chr12_+_103498542 0.91 ENSMUST00000021631.12
protein phosphatase 4, regulatory subunit 4
chr11_+_97576619 0.90 ENSMUST00000107584.8
ENSMUST00000107585.9
CDGSH iron sulfur domain 3
chr15_-_96929086 0.89 ENSMUST00000230086.2
solute carrier family 38, member 4
chr2_-_147888816 0.86 ENSMUST00000172928.2
ENSMUST00000047315.10
forkhead box A2
chr17_-_32639936 0.81 ENSMUST00000170392.9
ENSMUST00000237165.2
ENSMUST00000235892.2
ENSMUST00000114455.3
peptidoglycan recognition protein 2
chr1_+_34199333 0.81 ENSMUST00000183302.6
ENSMUST00000185897.7
ENSMUST00000185269.7
dystonin
chr18_+_20380397 0.81 ENSMUST00000054128.7
desmoglein 1 gamma
chr2_-_91025441 0.79 ENSMUST00000002177.9
nuclear receptor subfamily 1, group H, member 3
chr15_+_54975814 0.79 ENSMUST00000100660.11
DEP domain containing MTOR-interacting protein
chr10_+_128626772 0.77 ENSMUST00000219404.2
ENSMUST00000026411.8
matrix metallopeptidase 19
chr13_+_60749735 0.77 ENSMUST00000226059.2
ENSMUST00000077453.13
death associated protein kinase 1
chr7_+_130633776 0.73 ENSMUST00000084509.7
ENSMUST00000213064.3
ENSMUST00000208311.4
deleted in malignant brain tumors 1
chr11_+_97576724 0.73 ENSMUST00000107583.3
CDGSH iron sulfur domain 3
chr5_-_147831610 0.72 ENSMUST00000118527.8
ENSMUST00000031655.4
ENSMUST00000138244.2
solute carrier family 46, member 3
chr8_-_85500998 0.66 ENSMUST00000109762.8
nuclear factor I/X
chr1_+_167425953 0.65 ENSMUST00000015987.10
retinoid X receptor gamma
chr7_-_49286594 0.60 ENSMUST00000032717.7
developing brain homeobox 1
chr2_-_91025492 0.60 ENSMUST00000111354.2
nuclear receptor subfamily 1, group H, member 3
chr10_-_89568106 0.58 ENSMUST00000020109.5
ARP6 actin-related protein 6
chr3_-_10416369 0.57 ENSMUST00000108377.8
ENSMUST00000037839.12
zinc finger, AN1-type domain 1
chr12_+_59178072 0.57 ENSMUST00000176464.8
ENSMUST00000170992.9
ENSMUST00000176322.8
MIA SH3 domain ER export factor 2
chr4_+_135648041 0.55 ENSMUST00000030434.5
fucosidase, alpha-L- 1, tissue
chr2_-_93988229 0.54 ENSMUST00000028619.5
hydroxysteroid (17-beta) dehydrogenase 12
chr13_+_60749995 0.54 ENSMUST00000044083.9
death associated protein kinase 1
chr10_-_125225298 0.53 ENSMUST00000210780.2
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr2_-_94236991 0.53 ENSMUST00000111237.9
ENSMUST00000094801.5
ENSMUST00000111238.8
tetratricopeptide repeat domain 17
chr6_+_48906825 0.52 ENSMUST00000031837.8
diamine oxidase-like protein 1
chr13_+_119625345 0.52 ENSMUST00000099147.5
transmembrane protein 267
chr7_+_112118817 0.50 ENSMUST00000106640.2
parvin, alpha
chr12_+_59178258 0.49 ENSMUST00000177162.8
MIA SH3 domain ER export factor 2
chr7_-_34354924 0.49 ENSMUST00000032709.3
potassium channel tetramerisation domain containing 15
chr8_-_22966831 0.48 ENSMUST00000163774.3
ENSMUST00000033935.16
small integral membrane protein 19
chr4_-_109013807 0.48 ENSMUST00000161363.2
oxysterol binding protein-like 9
chr7_-_90125178 0.48 ENSMUST00000032843.9
transmembrane protein 126B
chr2_-_10135449 0.47 ENSMUST00000042290.14
inter-alpha trypsin inhibitor, heavy chain 2
chr7_+_30676465 0.46 ENSMUST00000058093.6
family with sequence similarity 187, member B
chr2_+_144435974 0.46 ENSMUST00000136628.2
small integral membrane protein 26
chr1_-_136881336 0.46 ENSMUST00000192929.6
nuclear receptor subfamily 5, group A, member 2
chr2_-_160169414 0.45 ENSMUST00000099127.3
predicted gene 826
chr17_+_45817750 0.44 ENSMUST00000024733.9
alanyl-tRNA synthetase 2, mitochondrial
chr3_+_137849608 0.44 ENSMUST00000159481.8
ENSMUST00000161141.2
tRNA methyltransferase 10A
chr19_+_44980565 0.43 ENSMUST00000179305.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr18_-_24663260 0.42 ENSMUST00000046206.5
regulation of nuclear pre-mRNA domain containing 1A
chr15_+_92495007 0.42 ENSMUST00000035399.10
PDZ domain containing RING finger 4
chr9_-_64160899 0.42 ENSMUST00000005066.9
mitogen-activated protein kinase kinase 1
chrX_-_112095181 0.41 ENSMUST00000026607.15
ENSMUST00000113388.3
choroidermia (RAB escort protein 1)
chr8_+_48277493 0.41 ENSMUST00000038693.8
claudin 22
chr14_-_20231871 0.40 ENSMUST00000024011.10
potassium channel, subfamily K, member 5
chr8_+_123103348 0.39 ENSMUST00000017622.12
ENSMUST00000093073.12
ENSMUST00000176699.2
zinc finger CCCH-type containing 18
chr2_-_63014622 0.39 ENSMUST00000075052.10
ENSMUST00000112454.8
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr6_-_67743756 0.38 ENSMUST00000103306.2
immunoglobulin kappa variable 1-131
chr18_+_36431732 0.37 ENSMUST00000210490.3
IgA inducing protein
chrX_-_110446022 0.37 ENSMUST00000156639.2
ribosomal protein S6 kinase polypeptide 6
chr14_-_56448874 0.37 ENSMUST00000022757.5
granzyme F
chr6_-_52160816 0.35 ENSMUST00000134831.2
homeobox A3
chr16_-_28748410 0.35 ENSMUST00000100023.3
Mab-21 domain containing 2
chr18_+_77877611 0.35 ENSMUST00000238172.2
proline-serine-threonine phosphatase-interacting protein 2
chr13_-_22913799 0.34 ENSMUST00000237024.2
ENSMUST00000236800.2
vomeronasal 1 receptor 207
chr7_+_18853778 0.32 ENSMUST00000053109.5
F-box protein 46
chr1_+_138201460 0.31 ENSMUST00000027643.6
ATPase, H+ transporting, lysosomal V1 subunit G3
chr8_-_73188887 0.31 ENSMUST00000109974.2
calreticulin 3
chr17_+_79359617 0.31 ENSMUST00000233916.2
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr17_-_35023521 0.31 ENSMUST00000025223.9
cytochrome P450, family 21, subfamily a, polypeptide 1
chr9_+_21279802 0.30 ENSMUST00000214474.2
interleukin enhancer binding factor 3
chrX_+_106193060 0.30 ENSMUST00000125676.8
ENSMUST00000180182.2
purinergic receptor P2Y, G-protein coupled 10B
chr6_-_92458324 0.29 ENSMUST00000113445.2
prickle planar cell polarity protein 2
chr3_-_98496123 0.29 ENSMUST00000178221.4
predicted gene 10681
chr9_+_57604895 0.29 ENSMUST00000034865.6
cytochrome P450, family 1, subfamily a, polypeptide 1
chr6_-_127746390 0.29 ENSMUST00000032500.9
protein arginine N-methyltransferase 8
chr4_+_145237329 0.29 ENSMUST00000105742.8
ENSMUST00000136309.8
zinc finger protein 990
chr12_+_76812301 0.28 ENSMUST00000041262.14
ENSMUST00000126408.2
ENSMUST00000110399.3
ENSMUST00000137826.8
churchill domain containing 1
farnesyltransferase, CAAX box, beta
chr6_+_127049865 0.28 ENSMUST00000000186.9
fibroblast growth factor 23
chr17_+_35327255 0.28 ENSMUST00000037849.3
lymphocyte antigen 6 complex, locus G5C
chr2_-_63014514 0.27 ENSMUST00000112452.2
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr13_-_22961570 0.27 ENSMUST00000227136.2
vomeronasal 1 receptor 208
chr19_+_38253077 0.26 ENSMUST00000198045.5
leucine-rich repeat LGI family, member 1
chr11_-_99241924 0.26 ENSMUST00000017732.3
keratin 27
chr8_+_22966736 0.25 ENSMUST00000067786.9
solute carrier family 20, member 2
chr4_+_146033882 0.25 ENSMUST00000105730.2
ENSMUST00000091878.6
zinc finger protein 987
chr19_+_38253105 0.24 ENSMUST00000196090.2
leucine-rich repeat LGI family, member 1
chr7_+_108549545 0.24 ENSMUST00000207583.2
tubby bipartite transcription factor
chr2_-_85592444 0.24 ENSMUST00000214255.2
olfactory receptor 1012
chr10_-_107321938 0.24 ENSMUST00000000445.2
myogenic factor 5
chr6_+_78382131 0.24 ENSMUST00000023906.4
regenerating islet-derived 2
chr8_+_22966889 0.24 ENSMUST00000209305.2
solute carrier family 20, member 2
chr3_+_115801869 0.24 ENSMUST00000106502.2
exostosin-like glycosyltransferase 2
chr12_-_88288251 0.23 ENSMUST00000177747.2
eukaryotic translation initiation factor 1A domain containing 15
chr2_+_81883566 0.23 ENSMUST00000047527.8
zinc finger protein 804A
chr7_+_101512922 0.23 ENSMUST00000209334.2
anaphase promoting complex C subunit 15
chr8_-_68270936 0.22 ENSMUST00000120071.8
pleckstrin and Sec7 domain containing 3
chr4_+_88640042 0.22 ENSMUST00000181601.2
predicted gene, 26566
chrX_+_106193167 0.22 ENSMUST00000137107.2
ENSMUST00000067249.3
purinergic receptor P2Y, G-protein coupled 10B
chrX_+_118836893 0.21 ENSMUST00000040961.3
ENSMUST00000113366.2
poly(A) binding protein, cytoplasmic 5
chr8_-_88686188 0.21 ENSMUST00000109655.9
zinc finger protein 423
chr11_+_87590720 0.21 ENSMUST00000040089.5
ring finger protein 43
chr7_+_123061535 0.21 ENSMUST00000098056.6
aquaporin 8
chr8_+_67149815 0.20 ENSMUST00000212588.2
neuropeptide Y receptor Y1
chr13_+_35059285 0.20 ENSMUST00000077853.5
pre-mRNA processing factor 4B
chr13_+_67052978 0.20 ENSMUST00000168767.9
predicted gene 10767
chr7_-_23907518 0.19 ENSMUST00000086006.12
zinc finger protein 111
chr14_-_68893253 0.19 ENSMUST00000225767.3
ENSMUST00000111072.8
ENSMUST00000022642.6
ENSMUST00000224039.2
a disintegrin and metallopeptidase domain 28
chr4_+_146093394 0.19 ENSMUST00000168483.9
zinc finger protein 600
chr13_-_55563028 0.19 ENSMUST00000054146.5
profilin 3
chr8_-_72124359 0.19 ENSMUST00000177517.8
ENSMUST00000030170.15
unc-13 homolog A
chr6_-_42301488 0.19 ENSMUST00000095974.4
family with sequence similarity 131, member B
chr2_+_36308959 0.19 ENSMUST00000216645.2
olfactory receptor 339
chr4_+_147106307 0.18 ENSMUST00000075775.6
reduced expression 2
chr12_-_36268171 0.18 ENSMUST00000020853.8
leucine rich repeat containing 72
chr18_+_62790356 0.18 ENSMUST00000162511.3
serine peptidase inhibitor, Kazal type 10
chr15_+_102927366 0.18 ENSMUST00000165375.3
homeobox C4
chr6_+_134617903 0.18 ENSMUST00000062755.10
BLOC-1 related complex subunit 5
chr17_-_90763300 0.17 ENSMUST00000159778.8
ENSMUST00000174337.8
ENSMUST00000172466.8
neurexin I
chr16_-_10131804 0.17 ENSMUST00000078357.5
epithelial membrane protein 2
chr16_+_48130819 0.16 ENSMUST00000097175.5
developmental pluripotency associated 2
chr9_+_78522783 0.16 ENSMUST00000093812.5
CD109 antigen
chr13_-_22993852 0.16 ENSMUST00000227038.2
ENSMUST00000227265.2
vomeronasal 1 receptor 209
chr1_-_5140504 0.16 ENSMUST00000147158.2
ENSMUST00000118000.8
regulator of G-protein signaling 20
chr13_-_8998267 0.16 ENSMUST00000187196.7
predicted gene 9745
chr5_+_31684331 0.16 ENSMUST00000114533.9
ENSMUST00000202214.4
ENSMUST00000201858.4
ENSMUST00000202950.4
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr12_+_4819022 0.16 ENSMUST00000219503.2
profilin family, member 4
chr3_-_30194559 0.16 ENSMUST00000108271.10
MDS1 and EVI1 complex locus
chr2_+_111156865 0.16 ENSMUST00000208176.3
olfactory receptor 1281
chr13_+_9002896 0.16 ENSMUST00000038598.3
isopentenyl-diphosphate delta isomerase 2
chr6_+_116185077 0.16 ENSMUST00000204051.2
WASH complex subunit 2`
chr2_-_111942878 0.15 ENSMUST00000217078.2
olfactory receptor 1315, pseudogene 1
chr11_+_115197980 0.15 ENSMUST00000055490.9
otopetrin 2
chr6_+_141470105 0.15 ENSMUST00000032362.12
ENSMUST00000205214.3
solute carrier organic anion transporter family, member 1c1
chr17_-_24199523 0.15 ENSMUST00000234765.2
protease, serine 30
chr18_+_37646674 0.15 ENSMUST00000061405.6
protocadherin beta 21
chr8_-_5155347 0.15 ENSMUST00000023835.3
solute carrier family 10, member 2
chr9_+_45749869 0.15 ENSMUST00000078111.11
ENSMUST00000034591.11
beta-site APP cleaving enzyme 1
chr6_+_116184991 0.14 ENSMUST00000036759.11
ENSMUST00000204476.3
WASH complex subunit 2`
chr7_-_119461027 0.14 ENSMUST00000137888.2
ENSMUST00000142120.2
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr7_+_123061497 0.14 ENSMUST00000033023.10
aquaporin 8
chr4_+_43384320 0.14 ENSMUST00000136360.2
RUN and SH3 domain containing 2
chr6_+_116483477 0.14 ENSMUST00000075756.3
olfactory receptor 212
chr6_-_122833109 0.14 ENSMUST00000042081.9
complement component 3a receptor 1
chr5_-_52723700 0.14 ENSMUST00000039750.7
leucine-rich repeat LGI family, member 2
chr1_-_170042947 0.13 ENSMUST00000027979.14
ENSMUST00000123399.2
U2AF homology motif (UHM) kinase 1
chr5_-_74838461 0.13 ENSMUST00000117525.8
ENSMUST00000113531.9
ENSMUST00000039744.13
ENSMUST00000121690.8
ligand of numb-protein X 1
chr10_+_76089674 0.13 ENSMUST00000036387.8
S100 protein, beta polypeptide, neural
chr19_+_38252984 0.13 ENSMUST00000198518.5
ENSMUST00000199812.5
leucine-rich repeat LGI family, member 1
chr7_+_87233554 0.13 ENSMUST00000125009.9
glutamate receptor, metabotropic 5
chr10_+_77885669 0.13 ENSMUST00000000746.12
DNA (cytosine-5-)-methyltransferase 3-like
chr7_-_37722938 0.13 ENSMUST00000206581.2
URI1, prefoldin-like chaperone
chr3_+_91921890 0.13 ENSMUST00000047660.5
peptidoglycan recognition protein 3
chrX_+_105059305 0.12 ENSMUST00000033582.5
cytochrome c oxidase subunit 7B
chr2_+_59442378 0.12 ENSMUST00000112568.8
ENSMUST00000037526.11
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chrX_+_106192510 0.12 ENSMUST00000147521.8
ENSMUST00000167673.2
purinergic receptor P2Y, G-protein coupled 10B
chr2_-_30249202 0.12 ENSMUST00000100215.11
ENSMUST00000113620.10
ENSMUST00000163668.3
ENSMUST00000028214.15
ENSMUST00000113621.10
SH3-domain GRB2-like endophilin B2
chr2_-_17395765 0.12 ENSMUST00000177966.2
nebulette
chr3_+_29136172 0.12 ENSMUST00000124809.8
EGF-like and EMI domain containing 1
chr7_-_140087224 0.12 ENSMUST00000209873.2
ENSMUST00000064392.8
ENSMUST00000215768.2
ENSMUST00000215340.2
olfactory receptor 536
chr16_+_95059121 0.12 ENSMUST00000113858.3
potassium inwardly-rectifying channel, subfamily J, member 15
chr7_+_27290969 0.12 ENSMUST00000108344.9
thymoma viral proto-oncogene 2
chr14_-_50536787 0.12 ENSMUST00000163469.2
olfactory receptor 733
chr7_-_103928939 0.12 ENSMUST00000051795.10
tripartite motif-containing 5
chr10_+_126836578 0.11 ENSMUST00000026500.12
ENSMUST00000142698.8
advillin
chrY_+_897782 0.11 ENSMUST00000189069.7
ENSMUST00000055032.14
lysine (K)-specific demethylase 5D
chr16_-_45352346 0.11 ENSMUST00000232600.2
predicted gene, 17783
chr17_+_43671314 0.11 ENSMUST00000226087.2
adhesion G protein-coupled receptor F5
chr4_-_115797118 0.11 ENSMUST00000124071.9
ENSMUST00000084338.7
diencephalon/mesencephalon homeobox 1
chr13_-_103042554 0.11 ENSMUST00000171791.8
microtubule associated serine/threonine kinase family member 4
chr11_-_98220466 0.11 ENSMUST00000041685.7
neurogenic differentiation 2
chr4_+_147576874 0.11 ENSMUST00000105721.9
zinc finger protein 982
chrX_-_74205226 0.11 ENSMUST00000165080.2
small integral membrane protein 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.8 4.8 GO:0008355 olfactory learning(GO:0008355)
0.7 4.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.6 4.7 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.4 1.3 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.3 1.4 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.3 1.0 GO:0006711 estrogen catabolic process(GO:0006711)
0.3 0.3 GO:0009804 coumarin metabolic process(GO:0009804)
0.3 0.9 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2 0.9 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.2 8.1 GO:0006825 copper ion transport(GO:0006825)
0.2 1.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 0.9 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 1.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 1.9 GO:0043589 skin morphogenesis(GO:0043589)
0.1 1.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302) liver regeneration(GO:0097421)
0.1 0.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.3 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 1.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 2.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.5 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.3 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.1 4.6 GO:0007566 embryo implantation(GO:0007566)
0.1 0.4 GO:0010159 specification of organ position(GO:0010159) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 1.0 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 2.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.2 GO:0042694 muscle cell fate specification(GO:0042694)
0.1 2.1 GO:0010842 retina layer formation(GO:0010842)
0.0 1.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:1903800 regulation of Golgi inheritance(GO:0090170) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.5 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 1.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:0097473 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.5 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.8 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.6 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.2 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 1.4 GO:0009268 response to pH(GO:0009268)
0.0 2.2 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.4 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.1 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.0 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.3 GO:0042448 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212) progesterone metabolic process(GO:0042448)
0.0 0.3 GO:0030432 peristalsis(GO:0030432)
0.0 0.5 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457) histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0051977 lysophospholipid transport(GO:0051977)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0001967 suckling behavior(GO:0001967)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 8.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.8 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.3 GO:0046691 intracellular canaliculus(GO:0046691)
0.1 1.8 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.0 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:1990462 omegasome(GO:1990462)
0.0 0.9 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
1.1 4.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
1.0 4.8 GO:0005186 pheromone activity(GO:0005186)
0.9 4.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.7 7.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 4.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.3 4.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.3 2.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.2 1.0 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.2 1.4 GO:0032810 sterol response element binding(GO:0032810)
0.2 0.5 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.2 1.8 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 0.5 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 1.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 1.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 0.9 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 1.0 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 2.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.2 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 1.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.3 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.1 0.4 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 2.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.3 GO:0016594 glycine binding(GO:0016594)
0.0 1.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 1.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0001602 peptide YY receptor activity(GO:0001601) pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 1.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.3 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 2.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 4.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.7 PID IFNG PATHWAY IFN-gamma pathway
0.0 3.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 8.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 2.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 1.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 4.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.8 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 1.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 7.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 4.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions