Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Otx1

Z-value: 1.01

Motif logo

logo of

Transcription factors associated with Otx1

Gene Symbol Gene ID Gene Info
Otx1
ENSMUSG00000005917.16 Otx1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Otx1mm39_v1_chr11_-_21951605_219516310.281.0e-01Click!

Activity profile of Otx1 motif

Sorted Z-values of Otx1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Otx1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr10_+_3923086 4.61 ENSMUST00000117291.8
ENSMUST00000120585.8
ENSMUST00000043735.8
Mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr8_+_117822593 3.95 ENSMUST00000034308.16
ENSMUST00000176860.2
Bco1
beta-carotene oxygenase 1
chr14_-_87378641 3.77 ENSMUST00000168889.3
ENSMUST00000022599.14
Diaph3
diaphanous related formin 3
chr11_+_94827050 3.72 ENSMUST00000001547.8
Col1a1
collagen, type I, alpha 1
chr2_+_91376650 3.25 ENSMUST00000099716.11
ENSMUST00000046769.16
ENSMUST00000111337.3
Ckap5
cytoskeleton associated protein 5
chr17_+_36172210 2.85 ENSMUST00000074259.15
ENSMUST00000174873.2
Nrm
nurim (nuclear envelope membrane protein)
chr11_+_78237492 2.48 ENSMUST00000100755.4
Unc119
unc-119 lipid binding chaperone
chr7_-_19410749 2.30 ENSMUST00000003074.16
Apoc2
apolipoprotein C-II
chr9_+_108356935 2.11 ENSMUST00000194147.2
ENSMUST00000065014.10
ENSMUST00000195483.6
ENSMUST00000195058.2
Lamb2
laminin, beta 2
chr10_-_93725619 1.94 ENSMUST00000181091.8
ENSMUST00000181217.8
ENSMUST00000047910.15
ENSMUST00000180688.2
Metap2
methionine aminopeptidase 2
chr13_-_61084358 1.85 ENSMUST00000225859.2
ENSMUST00000225167.2
ENSMUST00000021880.10
Gm49391
Ctla2a
predicted gene, 49391
cytotoxic T lymphocyte-associated protein 2 alpha
chr15_+_80017315 1.76 ENSMUST00000023050.9
Tab1
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chrX_-_165992145 1.67 ENSMUST00000112176.8
Tmsb4x
thymosin, beta 4, X chromosome
chr8_+_55024446 1.67 ENSMUST00000239166.2
ENSMUST00000239106.2
ENSMUST00000239152.2
Asb5
ankyrin repeat and SOCs box-containing 5
chr17_+_36172235 1.55 ENSMUST00000172931.2
Nrm
nurim (nuclear envelope membrane protein)
chr16_+_49620883 1.50 ENSMUST00000229640.2
Cd47
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr1_-_165535617 1.46 ENSMUST00000040357.11
Rcsd1
RCSD domain containing 1
chr11_-_106889291 1.45 ENSMUST00000124541.8
Kpna2
karyopherin (importin) alpha 2
chr9_-_62895197 1.42 ENSMUST00000216209.2
Pias1
protein inhibitor of activated STAT 1
chr5_-_104261556 1.40 ENSMUST00000031249.8
Sparcl1
SPARC-like 1
chr4_-_11965691 1.39 ENSMUST00000108301.8
ENSMUST00000095144.10
ENSMUST00000108302.8
Pdp1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr9_+_117888124 1.38 ENSMUST00000123690.2
Azi2
5-azacytidine induced gene 2
chr5_-_104261285 1.33 ENSMUST00000199947.2
Sparcl1
SPARC-like 1
chr1_-_85664246 1.31 ENSMUST00000064788.14
A630001G21Rik
RIKEN cDNA A630001G21 gene
chr5_-_65117375 1.26 ENSMUST00000062315.7
ENSMUST00000239485.2
ENSMUST00000201307.3
Tlr6
toll-like receptor 6
chr12_-_26506422 1.17 ENSMUST00000020970.10
Rsad2
radical S-adenosyl methionine domain containing 2
chr5_-_5799315 1.15 ENSMUST00000015796.9
Steap1
six transmembrane epithelial antigen of the prostate 1
chr11_+_115455260 1.14 ENSMUST00000021085.11
Nup85
nucleoporin 85
chr6_-_68609426 1.13 ENSMUST00000103328.3
Igkv10-96
immunoglobulin kappa variable 10-96
chr9_-_53521585 1.12 ENSMUST00000034547.6
Acat1
acetyl-Coenzyme A acetyltransferase 1
chr17_+_47922497 1.12 ENSMUST00000024778.3
Med20
mediator complex subunit 20
chr10_-_111829393 1.10 ENSMUST00000161870.3
Glipr1
GLI pathogenesis-related 1 (glioma)
chr6_-_136805184 1.06 ENSMUST00000116514.4
Wbp11
WW domain binding protein 11
chr18_+_24087725 1.00 ENSMUST00000225682.2
ENSMUST00000060762.6
Zfp397
zinc finger protein 397
chr4_-_137512682 0.98 ENSMUST00000133473.2
Alpl
alkaline phosphatase, liver/bone/kidney
chrX_+_36390430 0.95 ENSMUST00000016553.5
Nkap
NFKB activating protein
chr3_+_101284391 0.95 ENSMUST00000043983.11
Igsf3
immunoglobulin superfamily, member 3
chr12_-_114621406 0.94 ENSMUST00000192077.2
Ighv1-15
immunoglobulin heavy variable 1-15
chr12_-_13299197 0.89 ENSMUST00000071103.10
Ddx1
DEAD box helicase 1
chr2_-_153067297 0.89 ENSMUST00000099194.4
Tspyl3
TSPY-like 3
chr18_-_68562385 0.88 ENSMUST00000052347.8
Mc2r
melanocortin 2 receptor
chr1_-_53391778 0.88 ENSMUST00000236737.2
ENSMUST00000027264.10
ENSMUST00000123519.9
Gm50478
Asnsd1
predicted gene, 50478
asparagine synthetase domain containing 1
chr11_+_3913970 0.86 ENSMUST00000109985.8
ENSMUST00000020705.5
Pes1
pescadillo ribosomal biogenesis factor 1
chr1_-_118239146 0.85 ENSMUST00000027623.9
Tsn
translin
chr2_-_12306722 0.82 ENSMUST00000028106.11
Itga8
integrin alpha 8
chr13_+_21363602 0.77 ENSMUST00000222544.2
Trim27
tripartite motif-containing 27
chr16_+_91444730 0.76 ENSMUST00000119368.8
ENSMUST00000114037.9
ENSMUST00000114036.9
ENSMUST00000122302.8
Son
Son DNA binding protein
chr15_+_102391614 0.75 ENSMUST00000229432.2
Pcbp2
poly(rC) binding protein 2
chr1_+_118249558 0.74 ENSMUST00000027626.13
ENSMUST00000112688.10
Nifk
nucleolar protein interacting with the FHA domain of MKI67
chr5_+_25427860 0.71 ENSMUST00000045737.14
Galnt11
polypeptide N-acetylgalactosaminyltransferase 11
chr12_+_70499869 0.70 ENSMUST00000021471.13
Tmx1
thioredoxin-related transmembrane protein 1
chr13_-_61045252 0.69 ENSMUST00000021884.10
Ctla2b
cytotoxic T lymphocyte-associated protein 2 beta
chr2_-_151822114 0.68 ENSMUST00000062047.6
Fam110a
family with sequence similarity 110, member A
chr19_-_10847121 0.67 ENSMUST00000120524.2
ENSMUST00000025645.14
Tmem132a
transmembrane protein 132A
chr17_-_47922374 0.66 ENSMUST00000024783.9
Bysl
bystin-like
chr19_+_5074070 0.63 ENSMUST00000025826.7
ENSMUST00000237371.2
ENSMUST00000235416.2
Slc29a2
solute carrier family 29 (nucleoside transporters), member 2
chr9_-_20432562 0.61 ENSMUST00000215908.2
ENSMUST00000068296.8
ENSMUST00000174462.8
ENSMUST00000213418.2
Zfp266
zinc finger protein 266
chr1_+_186947683 0.60 ENSMUST00000065573.14
ENSMUST00000110943.9
ENSMUST00000044812.12
Gpatch2
G patch domain containing 2
chr8_-_46604742 0.57 ENSMUST00000041582.15
Snx25
sorting nexin 25
chr1_+_131838294 0.56 ENSMUST00000062264.8
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr6_+_58810674 0.55 ENSMUST00000041401.11
Herc3
hect domain and RLD 3
chr13_+_36142822 0.55 ENSMUST00000225537.2
Ppp1r3g
protein phosphatase 1, regulatory subunit 3G
chr10_-_39009844 0.55 ENSMUST00000134279.8
ENSMUST00000139743.8
ENSMUST00000149949.8
ENSMUST00000124941.8
ENSMUST00000125042.8
ENSMUST00000063204.9
Fam229b
family with sequence similarity 229, member B
chr13_-_63579497 0.53 ENSMUST00000160931.2
ENSMUST00000099444.10
ENSMUST00000220684.2
ENSMUST00000161977.8
ENSMUST00000163091.8
Fancc
Fanconi anemia, complementation group C
chr7_-_4066154 0.52 ENSMUST00000086401.10
ENSMUST00000068865.13
Lair1
leukocyte-associated Ig-like receptor 1
chr11_-_59678462 0.51 ENSMUST00000125307.2
Pld6
phospholipase D family, member 6
chr10_-_127047396 0.48 ENSMUST00000013970.9
Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr13_+_21364069 0.48 ENSMUST00000021761.13
Trim27
tripartite motif-containing 27
chr6_+_68657317 0.48 ENSMUST00000198735.2
Igkv10-95
immunoglobulin kappa variable 10-95
chr2_+_154498917 0.47 ENSMUST00000044277.10
Chmp4b
charged multivesicular body protein 4B
chr13_-_61045212 0.47 ENSMUST00000171347.9
Ctla2b
cytotoxic T lymphocyte-associated protein 2 beta
chr8_-_94825556 0.46 ENSMUST00000034206.6
Bbs2
Bardet-Biedl syndrome 2 (human)
chr13_+_21364330 0.46 ENSMUST00000223065.2
Trim27
tripartite motif-containing 27
chr19_+_12257218 0.45 ENSMUST00000207186.4
ENSMUST00000207915.2
Olfr1434
olfactory receptor 1434
chr4_-_123644091 0.44 ENSMUST00000102636.4
Akirin1
akirin 1
chr5_+_53713137 0.44 ENSMUST00000087360.9
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr6_+_67838100 0.44 ENSMUST00000200586.2
ENSMUST00000103309.3
Igkv17-127
immunoglobulin kappa variable 17-127
chr5_-_69748126 0.40 ENSMUST00000166298.8
Gnpda2
glucosamine-6-phosphate deaminase 2
chr4_-_126094910 0.39 ENSMUST00000136157.8
Thrap3
thyroid hormone receptor associated protein 3
chr2_+_112096154 0.39 ENSMUST00000110991.9
Slc12a6
solute carrier family 12, member 6
chr16_-_63684477 0.39 ENSMUST00000232654.2
ENSMUST00000064405.8
Epha3
Eph receptor A3
chr6_+_70332836 0.37 ENSMUST00000103390.3
Igkv8-18
immunoglobulin kappa variable 8-18
chr5_+_31454787 0.36 ENSMUST00000201166.4
ENSMUST00000072228.9
Gckr
glucokinase regulatory protein
chr7_+_27537982 0.33 ENSMUST00000205701.2
Zfp59
zinc finger protein 59
chr17_+_28075415 0.33 ENSMUST00000114849.3
Uhrf1bp1
UHRF1 (ICBP90) binding protein 1
chr19_-_42768374 0.33 ENSMUST00000069298.13
ENSMUST00000160455.8
ENSMUST00000162004.8
Hps1
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
chr16_-_18885809 0.33 ENSMUST00000200211.2
Iglj3
immunoglobulin lambda joining 3
chr7_-_4066125 0.32 ENSMUST00000108600.9
ENSMUST00000205296.2
Lair1
leukocyte-associated Ig-like receptor 1
chr12_-_98225676 0.31 ENSMUST00000021390.9
Galc
galactosylceramidase
chr17_+_21031817 0.31 ENSMUST00000232810.2
ENSMUST00000233712.2
ENSMUST00000232852.2
Vmn1r229
vomeronasal 1 receptor 229
chr3_+_95018324 0.31 ENSMUST00000009102.9
Vps72
vacuolar protein sorting 72
chr13_+_41169740 0.31 ENSMUST00000021790.7
Tmem14c
transmembrane protein 14C
chr7_+_103628383 0.30 ENSMUST00000098185.2
Olfr635
olfactory receptor 635
chr7_-_4066194 0.30 ENSMUST00000086400.13
Lair1
leukocyte-associated Ig-like receptor 1
chr4_+_74160705 0.29 ENSMUST00000077851.10
Kdm4c
lysine (K)-specific demethylase 4C
chr2_-_37312881 0.29 ENSMUST00000112936.4
ENSMUST00000112934.8
Rc3h2
ring finger and CCCH-type zinc finger domains 2
chr7_-_7250327 0.29 ENSMUST00000170922.2
Vmn2r29
vomeronasal 2, receptor 29
chr1_+_131838220 0.28 ENSMUST00000189946.7
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr2_-_156022054 0.28 ENSMUST00000126992.8
ENSMUST00000146288.8
ENSMUST00000029149.13
ENSMUST00000109587.9
ENSMUST00000109584.8
Rbm39
RNA binding motif protein 39
chr7_-_37970734 0.28 ENSMUST00000032585.8
Pop4
processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)
chr6_+_108771840 0.27 ENSMUST00000204483.2
Arl8b
ADP-ribosylation factor-like 8B
chr1_+_186947934 0.25 ENSMUST00000160471.8
Gpatch2
G patch domain containing 2
chr1_-_186947651 0.25 ENSMUST00000183819.8
Spata17
spermatogenesis associated 17
chr2_+_85715984 0.24 ENSMUST00000213441.3
Olfr1023
olfactory receptor 1023
chr15_+_78819119 0.24 ENSMUST00000138880.9
ENSMUST00000041164.4
Nol12
nucleolar protein 12
chr2_-_89273344 0.24 ENSMUST00000216123.2
Olfr1240
olfactory receptor 1240
chr3_+_66892979 0.24 ENSMUST00000162362.8
ENSMUST00000065074.14
ENSMUST00000065047.13
Rsrc1
arginine/serine-rich coiled-coil 1
chr13_-_21934675 0.24 ENSMUST00000102983.2
H4c12
H4 clustered histone 12
chr12_-_114012399 0.22 ENSMUST00000103468.3
Ighv11-2
immunoglobulin heavy variable V11-2
chr12_-_65120674 0.21 ENSMUST00000220983.2
ENSMUST00000220730.2
ENSMUST00000021332.10
Fkbp3
FK506 binding protein 3
chr8_-_96615138 0.21 ENSMUST00000034097.8
Got2
glutamatic-oxaloacetic transaminase 2, mitochondrial
chr8_-_55171699 0.20 ENSMUST00000144711.9
Wdr17
WD repeat domain 17
chr19_-_7017295 0.18 ENSMUST00000025918.9
Stip1
stress-induced phosphoprotein 1
chr5_-_100521343 0.17 ENSMUST00000182433.8
Sec31a
Sec31 homolog A (S. cerevisiae)
chr18_-_70274639 0.16 ENSMUST00000121693.8
Rab27b
RAB27B, member RAS oncogene family
chr3_+_66893031 0.15 ENSMUST00000046542.13
ENSMUST00000162693.8
Rsrc1
arginine/serine-rich coiled-coil 1
chr11_-_116165024 0.14 ENSMUST00000021133.16
Srp68
signal recognition particle 68
chr2_+_112114906 0.11 ENSMUST00000053666.8
Slc12a6
solute carrier family 12, member 6
chr19_-_41921676 0.11 ENSMUST00000075280.12
ENSMUST00000112123.4
Exosc1
exosome component 1
chr7_+_86444235 0.11 ENSMUST00000233099.2
ENSMUST00000164996.2
Vmn2r77
vomeronasal 2, receptor 77
chr1_-_186947618 0.10 ENSMUST00000110945.4
ENSMUST00000183931.8
ENSMUST00000027908.13
Spata17
spermatogenesis associated 17
chr7_-_7483017 0.09 ENSMUST00000094866.7
Vmn2r32
vomeronasal 2, receptor 32
chr10_-_7423341 0.09 ENSMUST00000169796.4
ENSMUST00000218087.2
Ulbp1
UL16 binding protein 1
chr6_-_67919524 0.08 ENSMUST00000196768.2
Igkv9-124
immunoglobulin kappa chain variable 9-124
chr11_-_116164928 0.08 ENSMUST00000106425.4
Srp68
signal recognition particle 68
chr2_-_87881473 0.08 ENSMUST00000183862.3
Olfr1162
olfactory receptor 1162
chr14_-_75185281 0.07 ENSMUST00000088970.7
ENSMUST00000228252.2
Lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr13_+_18901459 0.05 ENSMUST00000072961.6
Vps41
VPS41 HOPS complex subunit
chr7_-_7822866 0.05 ENSMUST00000169683.2
Vmn2r35
vomeronasal 2, receptor 35
chr7_+_135207505 0.04 ENSMUST00000210833.2
Ptpre
protein tyrosine phosphatase, receptor type, E
chr18_-_46730381 0.04 ENSMUST00000036030.14
Tmed7
transmembrane p24 trafficking protein 7
chr7_-_9687512 0.03 ENSMUST00000165611.2
Vmn2r48
vomeronasal 2, receptor 48
chr7_-_9839668 0.03 ENSMUST00000094863.6
Vmn2r51
vomeronasal 2, receptor 51
chr15_-_57128522 0.03 ENSMUST00000137764.2
ENSMUST00000022995.13
Slc22a22
solute carrier family 22 (organic cation transporter), member 22
chr9_+_106330437 0.02 ENSMUST00000185874.7
Pcbp4
poly(rC) binding protein 4
chr7_+_48038274 0.01 ENSMUST00000056676.5
Mrgprb8
MAS-related GPR, member B8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.7 2.1 GO:0072248 metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.6 2.5 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.6 2.3 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.5 3.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.5 3.7 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.4 1.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.3 1.3 GO:0035666 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136) TRIF-dependent toll-like receptor signaling pathway(GO:0035666) detection of bacterial lipopeptide(GO:0070340)
0.3 1.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.3 1.7 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.3 1.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.3 0.8 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.2 0.9 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.2 0.8 GO:0060382 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.2 4.0 GO:0042574 retinal metabolic process(GO:0042574)
0.2 3.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2 0.5 GO:0030719 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.1 1.5 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.1 1.5 GO:0008228 opsonization(GO:0008228)
0.1 1.9 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 0.4 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 1.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.5 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.5 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 1.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.7 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.4 GO:1905068 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 1.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.9 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.5 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.2 GO:0006533 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.1 0.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) nucleolus organization(GO:0007000)
0.1 0.9 GO:0032808 lacrimal gland development(GO:0032808)
0.1 1.9 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 1.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.5 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.4 GO:0009750 response to fructose(GO:0009750)
0.0 1.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0048069 eye pigmentation(GO:0048069) melanosome assembly(GO:1903232)
0.0 0.5 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.6 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 1.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 1.4 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.5 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 1.1 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.3 GO:0043486 histone exchange(GO:0043486)
0.0 0.8 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0005584 collagen type I trimer(GO:0005584)
0.5 2.1 GO:0005608 laminin-3 complex(GO:0005608)
0.2 0.9 GO:0071920 cleavage body(GO:0071920)
0.2 2.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 4.4 GO:0005652 nuclear lamina(GO:0005652)
0.1 3.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.9 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 2.7 GO:0051233 spindle midzone(GO:0051233)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 1.0 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.7 GO:0030904 retromer complex(GO:0030904)
0.0 0.5 GO:0034464 BBSome(GO:0034464)
0.0 1.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0031082 BLOC complex(GO:0031082)
0.0 5.4 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.4 2.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.3 1.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 1.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.3 1.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.9 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2 3.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 1.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 0.9 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.2 0.5 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 1.1 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 0.9 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 1.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 3.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.4 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.5 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 4.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.5 GO:2001069 glycogen binding(GO:2001069)
0.1 1.8 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.3 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.8 GO:0050733 RS domain binding(GO:0050733)
0.1 0.2 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.8 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 1.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 1.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.6 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 3.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 1.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 5.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 3.3 PID AURORA A PATHWAY Aurora A signaling
0.0 1.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 3.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 1.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 2.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 3.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 2.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins