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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Pax2

Z-value: 2.50

Motif logo

Transcription factors associated with Pax2

Gene Symbol Gene ID Gene Info
ENSMUSG00000004231.16 Pax2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pax2mm39_v1_chr19_+_44745833_44745833-0.241.7e-01Click!

Activity profile of Pax2 motif

Sorted Z-values of Pax2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_84497718 10.87 ENSMUST00000085192.7
ENSMUST00000220491.2
aldehyde dehydrogenase family 6, subfamily A1
chr14_+_55798362 7.44 ENSMUST00000072530.11
ENSMUST00000128490.9
DDB1 and CUL4 associated factor 11
chr14_+_55797468 7.16 ENSMUST00000147981.2
ENSMUST00000133256.8
DDB1 and CUL4 associated factor 11
chr14_+_55797934 6.97 ENSMUST00000121622.8
ENSMUST00000143431.2
ENSMUST00000150481.8
DDB1 and CUL4 associated factor 11
chr7_-_34914675 6.53 ENSMUST00000118444.3
ENSMUST00000122409.8
low density lipoprotein receptor-related protein 3
chr3_+_89960121 6.30 ENSMUST00000160640.8
ENSMUST00000029552.13
ENSMUST00000162114.8
ENSMUST00000068798.13
RIKEN cDNA 4933434E20 gene
chr8_+_13209141 5.78 ENSMUST00000033824.8
lysosomal-associated membrane protein 1
chr16_-_97763780 5.54 ENSMUST00000232187.2
ENSMUST00000231263.2
ENSMUST00000052089.9
ENSMUST00000063605.15
ENSMUST00000113734.9
ENSMUST00000231560.2
ENSMUST00000232165.2
zinc finger and BTB domain containing 21
C2 calcium-dependent domain containing 2
chr16_+_44979086 5.49 ENSMUST00000023343.4
autophagy related 3
chr14_-_47426863 5.41 ENSMUST00000089959.7
GTP cyclohydrolase 1
chr10_-_62322551 4.48 ENSMUST00000105447.11
VPS26 retromer complex component A
chr17_-_46956920 4.44 ENSMUST00000233974.2
kinesin light chain 4
chr17_-_27158514 4.29 ENSMUST00000114935.9
ENSMUST00000025027.10
cutA divalent cation tolerance homolog
chr4_-_148123223 4.24 ENSMUST00000030879.12
ENSMUST00000137724.8
chloride channel, voltage-sensitive 6
chr10_+_41395410 4.07 ENSMUST00000019962.15
CD164 antigen
chr6_+_129510117 4.06 ENSMUST00000032264.9
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr14_+_4230569 4.05 ENSMUST00000090543.6
nuclear receptor subfamily 1, group D, member 2
chr1_+_128171859 3.97 ENSMUST00000027592.6
UBX domain protein 4
chr14_+_55797443 3.91 ENSMUST00000117236.8
DDB1 and CUL4 associated factor 11
chr1_+_13738967 3.88 ENSMUST00000088542.4
X-linked Kx blood group related 9
chr1_+_106099482 3.86 ENSMUST00000061047.7
PH domain and leucine rich repeat protein phosphatase 1
chr6_+_17463925 3.82 ENSMUST00000115442.8
met proto-oncogene
chr16_-_44979013 3.72 ENSMUST00000023344.10
solute carrier family 35, member A5
chr3_+_67490068 3.61 ENSMUST00000029344.10
major facilitator superfamily domain containing 1
chr14_+_14475188 3.54 ENSMUST00000026315.8
deoxyribonuclease 1-like 3
chr3_+_95226093 3.52 ENSMUST00000139866.2
ceramide synthase 2
chr10_-_62322356 3.44 ENSMUST00000092473.5
VPS26 retromer complex component A
chr10_+_41395870 3.40 ENSMUST00000189300.2
CD164 antigen
chr15_+_99291100 3.39 ENSMUST00000159209.8
transmembrane BAX inhibitor motif containing 6
chr15_+_99291491 3.37 ENSMUST00000159531.3
transmembrane BAX inhibitor motif containing 6
chr15_-_81283795 3.36 ENSMUST00000023039.15
suppression of tumorigenicity 13
chr15_+_99291455 3.20 ENSMUST00000162624.8
transmembrane BAX inhibitor motif containing 6
chr3_-_146302343 3.09 ENSMUST00000029836.9
deoxyribonuclease II beta
chr4_-_155430153 3.08 ENSMUST00000103178.11
protein kinase C, zeta
chr1_+_88139678 2.97 ENSMUST00000073049.7
UDP glucuronosyltransferase 1 family, polypeptide A1
chr9_-_64160899 2.97 ENSMUST00000005066.9
mitogen-activated protein kinase kinase 1
chr1_-_136888118 2.96 ENSMUST00000192357.6
ENSMUST00000027649.14
nuclear receptor subfamily 5, group A, member 2
chr11_+_35660288 2.95 ENSMUST00000018990.8
pantothenate kinase 3
chr15_-_81284244 2.89 ENSMUST00000172107.8
ENSMUST00000169204.2
ENSMUST00000163382.2
suppression of tumorigenicity 13
chr16_-_44978929 2.87 ENSMUST00000181177.2
solute carrier family 35, member A5
chr4_+_62278932 2.79 ENSMUST00000084526.12
solute carrier family 31, member 1
chr5_-_151113619 2.78 ENSMUST00000062015.15
ENSMUST00000110483.9
StAR-related lipid transfer (START) domain containing 13
chr10_-_62322451 2.76 ENSMUST00000217868.2
VPS26 retromer complex component A
chr13_-_64422775 2.76 ENSMUST00000221634.2
ENSMUST00000039318.16
CDC14 cell division cycle 14B
chr2_+_164675697 2.76 ENSMUST00000143780.9
cathepsin A
chr1_+_75119419 2.74 ENSMUST00000097694.11
ENSMUST00000190240.7
reticulophagy regulator family member 2
chr1_-_183078488 2.70 ENSMUST00000057062.12
BRO1 domain and CAAX motif containing
chrX_-_161671421 2.68 ENSMUST00000033723.4
synapse associated protein 1
chr16_-_44978986 2.67 ENSMUST00000180636.8
solute carrier family 35, member A5
chr2_+_155223728 2.67 ENSMUST00000043237.14
ENSMUST00000174685.8
transformation related protein 53 inducible nuclear protein 2
chr7_+_109617456 2.61 ENSMUST00000084731.5
importin 7
chr1_+_75119472 2.60 ENSMUST00000189650.7
reticulophagy regulator family member 2
chr1_-_175319842 2.59 ENSMUST00000195324.6
ENSMUST00000192227.6
ENSMUST00000194555.6
regulator of G protein signaling 7
chr17_-_64170786 2.58 ENSMUST00000050753.4
RIKEN cDNA A930002H24 gene
chr6_-_113508536 2.56 ENSMUST00000032425.7
ER membrane protein complex subunit 3
chr18_-_31742946 2.55 ENSMUST00000060396.7
solute carrier family 25, member 46
chr6_+_90439596 2.55 ENSMUST00000203039.3
Kruppel-like factor 15
chr6_+_90439544 2.53 ENSMUST00000032174.12
Kruppel-like factor 15
chr4_-_129083251 2.52 ENSMUST00000117965.8
S100P binding protein
chr5_-_66309244 2.49 ENSMUST00000167950.8
RNA binding motif protein 47
chr7_+_46445512 2.47 ENSMUST00000006774.11
ENSMUST00000165031.8
general transcription factor II H, polypeptide 1
chr2_+_166647426 2.47 ENSMUST00000099078.10
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr6_+_121320339 2.46 ENSMUST00000168295.2
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr5_-_124564014 2.43 ENSMUST00000196329.5
ENSMUST00000196644.5
strawberry notch 1
chr6_-_33037107 2.43 ENSMUST00000115091.2
ENSMUST00000127666.8
coiled-coil-helix-coiled-coil-helix domain containing 3
chr1_+_75119809 2.42 ENSMUST00000186037.7
ENSMUST00000187901.2
reticulophagy regulator family member 2
chr5_-_66308421 2.39 ENSMUST00000200775.4
ENSMUST00000094756.11
RNA binding motif protein 47
chr6_-_33037191 2.37 ENSMUST00000066379.11
coiled-coil-helix-coiled-coil-helix domain containing 3
chrX_+_67722230 2.35 ENSMUST00000114656.8
FMRP translational regulator 1
chr17_+_46694646 2.35 ENSMUST00000113481.9
ENSMUST00000138127.8
zinc finger protein 318
chr6_+_17463748 2.31 ENSMUST00000115443.8
met proto-oncogene
chr3_-_95789338 2.29 ENSMUST00000161994.2
circadian associated repressor of transcription
chr9_+_43978290 2.27 ENSMUST00000034508.14
ubiquitin specific peptidase 2
chr5_-_124563611 2.25 ENSMUST00000198420.5
strawberry notch 1
chr11_-_120521382 2.24 ENSMUST00000106181.8
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr11_+_53241561 2.18 ENSMUST00000060945.12
AF4/FMR2 family, member 4
chr7_-_45109262 2.13 ENSMUST00000094434.13
ferritin light polypeptide 1
chr2_-_48839218 2.08 ENSMUST00000090976.10
ENSMUST00000149679.8
origin recognition complex, subunit 4
chr3_-_95789505 2.07 ENSMUST00000159863.2
ENSMUST00000159739.8
ENSMUST00000036418.10
ENSMUST00000161866.8
circadian associated repressor of transcription
chr16_-_4867703 2.06 ENSMUST00000115844.3
ENSMUST00000023189.15
glyoxylate reductase 1 homolog (Arabidopsis)
chr9_-_21913833 2.04 ENSMUST00000115336.10
outer dynein arm docking complex subunit 3
chr8_-_85573489 2.03 ENSMUST00000003912.7
calreticulin
chr11_+_120563844 2.02 ENSMUST00000106158.9
ENSMUST00000103016.8
ENSMUST00000168714.9
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr7_+_44499818 2.00 ENSMUST00000136232.2
ENSMUST00000207223.2
AKT1 substrate 1 (proline-rich)
chr5_+_138170259 2.00 ENSMUST00000019662.11
ENSMUST00000151318.8
adaptor-related protein complex AP-4, mu 1
chr2_-_48839276 1.98 ENSMUST00000028098.11
origin recognition complex, subunit 4
chr4_+_99544536 1.97 ENSMUST00000087285.5
forkhead box D3
chr14_+_4230658 1.96 ENSMUST00000225491.2
nuclear receptor subfamily 1, group D, member 2
chr12_+_84498196 1.95 ENSMUST00000137170.3
lin-52 homolog (C. elegans)
chr2_+_126549239 1.91 ENSMUST00000028841.14
ENSMUST00000110416.3
ubiquitin specific peptidase 8
chr7_-_127545896 1.91 ENSMUST00000118755.8
ENSMUST00000094026.10
protease, serine 36
chr11_+_120564185 1.90 ENSMUST00000135346.8
ENSMUST00000127269.8
ENSMUST00000131727.9
ENSMUST00000149389.8
ENSMUST00000153346.8
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr15_+_81284333 1.89 ENSMUST00000163754.9
ENSMUST00000041609.11
X-prolyl aminopeptidase 3, mitochondrial
chr17_+_44114894 1.84 ENSMUST00000044895.13
regulator of calcineurin 2
chr9_-_21913896 1.84 ENSMUST00000044926.6
outer dynein arm docking complex subunit 3
chr10_-_63174801 1.84 ENSMUST00000020257.13
ENSMUST00000177694.8
ENSMUST00000105442.3
sirtuin 1
chr13_-_64422693 1.83 ENSMUST00000109770.2
CDC14 cell division cycle 14B
chr5_-_124563969 1.80 ENSMUST00000065263.12
strawberry notch 1
chr2_+_155224105 1.77 ENSMUST00000134218.2
transformation related protein 53 inducible nuclear protein 2
chr6_+_143112936 1.76 ENSMUST00000204947.3
ENSMUST00000032413.7
ENSMUST00000205256.2
ethanolamine kinase 1
chr2_-_30176324 1.75 ENSMUST00000100219.5
dolichol kinase
chr2_+_91287846 1.74 ENSMUST00000028689.4
low density lipoprotein receptor-related protein 4
chr16_-_44978546 1.74 ENSMUST00000114600.2
solute carrier family 35, member A5
chr3_+_96542746 1.71 ENSMUST00000118557.8
peroxisomal biogenesis factor 11 beta
chr5_-_123822351 1.68 ENSMUST00000111564.8
ENSMUST00000063905.12
CAP-GLY domain containing linker protein 1
chr3_+_96543143 1.68 ENSMUST00000165842.3
peroxisomal biogenesis factor 11 beta
chr3_+_96542933 1.65 ENSMUST00000048766.15
peroxisomal biogenesis factor 11 beta
chr1_+_191638854 1.65 ENSMUST00000044954.7
solute carrier family 30 (zinc transporter), member 1
chr2_+_48839505 1.65 ENSMUST00000112745.8
ENSMUST00000112754.8
methyl-CpG binding domain protein 5
chr5_-_113285852 1.65 ENSMUST00000212276.2
RIKEN cDNA 2900026A02 gene
chrX_+_165127688 1.64 ENSMUST00000112223.8
ENSMUST00000112224.8
ENSMUST00000112229.9
ENSMUST00000112228.8
ENSMUST00000112227.9
ENSMUST00000112226.3
glycoprotein m6b
chr5_-_124563636 1.64 ENSMUST00000196711.5
ENSMUST00000200474.5
ENSMUST00000199808.5
strawberry notch 1
chr2_+_155118217 1.63 ENSMUST00000029128.4
microtubule-associated protein 1 light chain 3 alpha
chr1_-_10302895 1.62 ENSMUST00000088615.11
ENSMUST00000131556.2
ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
chr19_-_60456742 1.61 ENSMUST00000051277.4
prolactin releasing hormone receptor
chr6_+_17463819 1.61 ENSMUST00000140070.8
met proto-oncogene
chr9_+_43978369 1.60 ENSMUST00000177054.8
ubiquitin specific peptidase 2
chr16_-_5021843 1.58 ENSMUST00000147567.2
ENSMUST00000023911.11
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr2_+_19662529 1.58 ENSMUST00000052168.6
OTU domain containing 1
chr4_-_129083392 1.57 ENSMUST00000117497.8
ENSMUST00000117350.2
S100P binding protein
chr11_+_117545037 1.57 ENSMUST00000026658.13
trinucleotide repeat containing 6C
chr15_-_53209513 1.56 ENSMUST00000077273.9
exostosin glycosyltransferase 1
chr1_+_171173252 1.56 ENSMUST00000006579.5
prefoldin 2
chr4_-_129083439 1.55 ENSMUST00000106059.8
S100P binding protein
chr2_-_37593287 1.51 ENSMUST00000072186.12
spermatid perinuclear RNA binding protein
chr5_+_24633206 1.48 ENSMUST00000115049.9
solute carrier family 4 (anion exchanger), member 2
chr7_-_129867967 1.48 ENSMUST00000117872.8
ENSMUST00000120187.9
fibroblast growth factor receptor 2
chr16_-_44978816 1.48 ENSMUST00000181750.2
solute carrier family 35, member A5
chrX_+_70860378 1.47 ENSMUST00000114575.4
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr14_+_30741115 1.47 ENSMUST00000112094.8
ENSMUST00000144009.2
polybromo 1
chr5_-_123822338 1.46 ENSMUST00000111561.8
CAP-GLY domain containing linker protein 1
chr11_-_101062111 1.46 ENSMUST00000164474.8
ENSMUST00000043397.14
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr1_+_131935342 1.45 ENSMUST00000086556.12
ELK4, member of ETS oncogene family
chr2_+_3514071 1.39 ENSMUST00000036350.3
cerebral dopamine neurotrophic factor
chr1_-_183078800 1.39 ENSMUST00000163528.8
BRO1 domain and CAAX motif containing
chr7_+_44499374 1.38 ENSMUST00000141311.8
ENSMUST00000107880.9
ENSMUST00000208384.2
AKT1 substrate 1 (proline-rich)
chr1_-_155617773 1.38 ENSMUST00000027740.14
LIM homeobox protein 4
chr19_-_42117420 1.37 ENSMUST00000161873.2
ENSMUST00000018965.4
arginine vasopressin-induced 1
chr17_-_65920481 1.36 ENSMUST00000024897.10
vesicle-associated membrane protein, associated protein A
chr10_+_126899396 1.36 ENSMUST00000006911.12
cyclin-dependent kinase 4
chr14_-_72840373 1.35 ENSMUST00000162825.8
fibronectin type III domain containing 3A
chr1_-_20854490 1.35 ENSMUST00000039046.10
interleukin 17F
chr7_+_27878894 1.35 ENSMUST00000085901.13
ENSMUST00000172761.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr7_+_125307060 1.35 ENSMUST00000124223.8
ENSMUST00000069660.13
katanin interacting protein
chr11_+_117545618 1.34 ENSMUST00000106344.8
trinucleotide repeat containing 6C
chr10_-_17823736 1.31 ENSMUST00000037879.8
hdc homolog, cell cycle regulator
chr4_+_48585275 1.29 ENSMUST00000123476.8
transmembrane protein with EGF-like and two follistatin-like domains 1
chr1_-_130643471 1.28 ENSMUST00000066863.13
ENSMUST00000169659.8
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr13_-_64300964 1.27 ENSMUST00000059817.12
ENSMUST00000117241.2
zinc finger protein 367
chrX_+_70860357 1.26 ENSMUST00000114576.9
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr11_-_101061153 1.25 ENSMUST00000123864.2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr7_+_121666388 1.25 ENSMUST00000033158.6
ubiquitin family domain containing 1
chr6_+_7555053 1.24 ENSMUST00000090679.9
ENSMUST00000184986.2
tachykinin 1
chr1_+_87254729 1.23 ENSMUST00000172794.8
ENSMUST00000164992.9
ENSMUST00000173173.8
GRB10 interacting GYF protein 2
chr1_-_30912662 1.19 ENSMUST00000186733.7
PHD finger protein 3
chr10_-_128759331 1.17 ENSMUST00000153731.8
ENSMUST00000026405.10
biogenesis of lysosomal organelles complex-1, subunit 1
chr10_+_121200984 1.15 ENSMUST00000040344.7
glucosamine (N-acetyl)-6-sulfatase
chr8_+_3550533 1.15 ENSMUST00000208306.2
mucolipin 1
chr2_+_160573604 1.15 ENSMUST00000174885.2
ENSMUST00000109462.8
phospholipase C, gamma 1
chr8_+_3550450 1.14 ENSMUST00000004683.13
ENSMUST00000160338.2
mucolipin 1
chr10_+_98750268 1.14 ENSMUST00000219557.2
ATPase, Ca++ transporting, plasma membrane 1
chr9_-_91247831 1.13 ENSMUST00000065360.5
zinc finger protein of the cerebellum 1
chr7_-_121666486 1.11 ENSMUST00000033159.4
glutamyl-tRNA synthetase 2, mitochondrial
chr14_+_30741082 1.11 ENSMUST00000112098.11
ENSMUST00000112095.8
ENSMUST00000112106.8
ENSMUST00000146325.8
polybromo 1
chr3_-_89820451 1.11 ENSMUST00000029559.7
ENSMUST00000197679.5
interleukin 6 receptor, alpha
chr1_-_30912916 1.09 ENSMUST00000188780.2
PHD finger protein 3
chr7_-_46445085 1.07 ENSMUST00000123725.2
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
chr13_-_92268156 1.07 ENSMUST00000151408.9
ENSMUST00000216219.2
RAS protein-specific guanine nucleotide-releasing factor 2
chr9_-_91247809 1.07 ENSMUST00000034927.13
zinc finger protein of the cerebellum 1
chr12_+_4284009 1.04 ENSMUST00000179139.3
peptidyl-tRNA hydrolase domain containing 1
chr4_-_126096112 1.03 ENSMUST00000142125.2
ENSMUST00000106141.3
thyroid hormone receptor associated protein 3
chrX_+_67722147 1.03 ENSMUST00000088546.12
FMRP translational regulator 1
chr7_-_46445305 1.02 ENSMUST00000107653.8
ENSMUST00000107654.8
ENSMUST00000014562.14
ENSMUST00000152759.8
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
chr17_-_56916771 1.02 ENSMUST00000052832.6
mitochondrial contact site and cristae organizing system subunit 13
chr4_-_119279551 1.01 ENSMUST00000106316.2
ENSMUST00000030385.13
phosphopantothenoylcysteine synthetase
chr6_+_116184991 1.01 ENSMUST00000036759.11
ENSMUST00000204476.3
WASH complex subunit 2`
chr5_-_66308666 0.99 ENSMUST00000201561.4
RNA binding motif protein 47
chr9_+_59446823 0.99 ENSMUST00000026262.8
hexosaminidase A
chr6_-_108162513 0.97 ENSMUST00000167338.8
ENSMUST00000172188.2
ENSMUST00000032191.16
sulfatase modifying factor 1
chr12_-_85421467 0.97 ENSMUST00000040766.9
transmembrane p24 trafficking protein 10
chr1_+_183078573 0.97 ENSMUST00000109166.8
axin interactor, dorsalization associated
chr10_-_127504416 0.97 ENSMUST00000129252.2
Ngfi-A binding protein 2
chr1_-_43131598 0.94 ENSMUST00000188728.2
transforming growth factor, beta receptor associated protein 1
chr4_-_129083335 0.93 ENSMUST00000106061.9
ENSMUST00000072431.13
S100P binding protein
chr14_+_30741140 0.92 ENSMUST00000052239.12
polybromo 1
chr2_+_180570793 0.92 ENSMUST00000108875.2
baculoviral IAP repeat-containing 7 (livin)
chr7_+_16043502 0.91 ENSMUST00000002152.13
BCL2 binding component 3
chr11_-_83320281 0.91 ENSMUST00000052521.9
growth arrest-specific 2 like 2
chr15_+_59520199 0.91 ENSMUST00000067543.8
tribbles pseudokinase 1
chr15_+_59520493 0.89 ENSMUST00000118228.2
tribbles pseudokinase 1
chr15_-_93234681 0.87 ENSMUST00000080299.7
YY1 associated factor 2
chr16_+_17577464 0.86 ENSMUST00000129199.8
kelch-like 22
chr5_-_24745970 0.86 ENSMUST00000117900.8
ankyrin repeat and SOCS box-containing 10
chr17_-_67939702 0.85 ENSMUST00000097290.4
leucine rich repeat containing 30
chr11_-_118931731 0.84 ENSMUST00000026663.8
chromobox 8
chr5_-_65855199 0.84 ENSMUST00000031104.7
PDS5 cohesin associated factor A
chr2_+_74557418 0.84 ENSMUST00000111980.4
homeobox D4
chr17_+_34043536 0.84 ENSMUST00000048249.8
NADH:ubiquinone oxidoreductase subunit A7
chr7_+_125307116 0.83 ENSMUST00000148701.4
katanin interacting protein
chr4_+_126971167 0.81 ENSMUST00000046751.13
ENSMUST00000094713.4
zinc finger, MYM-type 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.9 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
2.0 10.0 GO:0031438 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
1.9 5.8 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
1.4 5.4 GO:0014916 regulation of lung blood pressure(GO:0014916)
1.3 3.9 GO:1901254 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
1.1 7.7 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.0 5.0 GO:0044375 regulation of peroxisome size(GO:0044375)
1.0 3.0 GO:0018879 biphenyl metabolic process(GO:0018879)
0.9 2.8 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.9 6.2 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.9 3.5 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.9 2.6 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.8 2.5 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.7 2.2 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365)
0.7 3.5 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.7 2.0 GO:0002501 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.6 3.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.6 1.8 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.6 2.8 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.6 1.7 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.5 3.0 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.5 2.5 GO:0009992 cellular water homeostasis(GO:0009992)
0.5 3.9 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.5 1.4 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.5 0.5 GO:0072301 regulation of metanephric glomerular mesangial cell proliferation(GO:0072301)
0.5 5.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.4 3.1 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.4 1.7 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.4 2.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.4 2.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.4 4.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.4 1.2 GO:0035934 corticosterone secretion(GO:0035934)
0.4 1.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.4 6.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.4 1.6 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.4 2.8 GO:0072719 cellular response to cisplatin(GO:0072719) copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.4 10.7 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.4 1.4 GO:0021918 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.3 4.8 GO:0042407 cristae formation(GO:0042407)
0.3 1.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.3 1.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.3 1.4 GO:0045423 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.2 3.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 8.2 GO:0045475 locomotor rhythm(GO:0045475)
0.2 1.0 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.2 4.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 5.5 GO:0044804 nucleophagy(GO:0044804) negative regulation of phagocytosis(GO:0050765)
0.2 1.5 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 2.7 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 1.0 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.2 0.9 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 2.9 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 1.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 1.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 3.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.2 1.4 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.2 5.1 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.2 6.0 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.2 0.8 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2 1.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.2 0.6 GO:0061055 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.2 1.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.6 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.1 2.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 1.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.4 GO:0060112 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982) generation of ovulation cycle rhythm(GO:0060112)
0.1 0.6 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.9 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 1.8 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 1.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.5 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 3.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 2.0 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.0 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.3 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845) negative regulation of histone phosphorylation(GO:0033128)
0.1 1.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.1 1.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.6 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 2.0 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 1.4 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 7.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.9 GO:0003094 glomerular filtration(GO:0003094)
0.1 0.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.5 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 17.0 GO:0008643 carbohydrate transport(GO:0008643)
0.1 1.8 GO:0007614 short-term memory(GO:0007614) locomotion involved in locomotory behavior(GO:0031987)
0.1 2.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 5.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 2.3 GO:0097352 autophagosome maturation(GO:0097352)
0.1 0.6 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 1.1 GO:0070050 negative thymic T cell selection(GO:0045060) neuron cellular homeostasis(GO:0070050)
0.1 1.1 GO:1990403 embryonic brain development(GO:1990403)
0.1 1.8 GO:0061157 mRNA destabilization(GO:0061157)
0.1 0.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 1.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.5 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.0 0.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 1.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.9 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 2.0 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 2.9 GO:0000045 autophagosome assembly(GO:0000045)
0.0 4.0 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 2.7 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.0 0.9 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 2.2 GO:0007628 adult walking behavior(GO:0007628)
0.0 0.8 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 1.1 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.5 GO:0090190 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 1.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0042637 catagen(GO:0042637)
0.0 0.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.7 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 1.4 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.5 GO:0006821 chloride transport(GO:0006821)
0.0 2.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.6 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.7 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 1.2 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 2.2 GO:0007286 spermatid development(GO:0007286)
0.0 0.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.2 GO:0060394 maintenance of gastrointestinal epithelium(GO:0030277) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 1.1 GO:0030203 glycosaminoglycan metabolic process(GO:0030203)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 10.7 GO:0030906 retromer, cargo-selective complex(GO:0030906)
1.9 5.8 GO:0061474 phagolysosome membrane(GO:0061474)
1.0 3.9 GO:0019034 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
0.6 25.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.6 2.5 GO:0005879 axonemal microtubule(GO:0005879) symmetric synapse(GO:0032280)
0.6 4.8 GO:0061617 MICOS complex(GO:0061617)
0.5 2.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.4 4.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 5.8 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.3 3.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.3 3.4 GO:0031931 TORC1 complex(GO:0031931)
0.3 1.8 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 3.1 GO:0045179 apical cortex(GO:0045179)
0.3 1.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 2.5 GO:0000439 core TFIIH complex(GO:0000439)
0.3 3.8 GO:0044754 autolysosome(GO:0044754)
0.2 1.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 2.0 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.2 3.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 2.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 4.9 GO:0000421 autophagosome membrane(GO:0000421)
0.2 5.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 1.6 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.1 GO:0005827 polar microtubule(GO:0005827)
0.1 1.8 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.9 GO:0033263 CORVET complex(GO:0033263)
0.1 1.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.7 GO:0071203 WASH complex(GO:0071203)
0.1 1.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 2.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 2.6 GO:0044292 dendrite terminus(GO:0044292)
0.1 3.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.9 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.7 GO:0016600 flotillin complex(GO:0016600)
0.1 3.5 GO:0090544 BAF-type complex(GO:0090544)
0.1 7.7 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.1 GO:0000786 nucleosome(GO:0000786)
0.1 3.5 GO:0005776 autophagosome(GO:0005776)
0.1 1.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.6 GO:0010369 chromocenter(GO:0010369)
0.1 1.0 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 13.7 GO:0000139 Golgi membrane(GO:0000139)
0.0 20.5 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 2.8 GO:0005811 lipid particle(GO:0005811)
0.0 3.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 3.5 GO:0000922 spindle pole(GO:0000922)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 2.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 4.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 3.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 1.1 GO:0032420 stereocilium(GO:0032420)
0.0 4.9 GO:0005938 cell cortex(GO:0005938)
0.0 4.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 3.9 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
1.8 5.5 GO:0019776 Atg8 ligase activity(GO:0019776)
1.7 10.0 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.7 6.2 GO:0032564 dATP binding(GO:0032564)
0.7 2.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.6 3.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.6 1.8 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.6 5.4 GO:0019238 cyclohydrolase activity(GO:0019238)
0.5 1.6 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.5 3.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.5 3.9 GO:0033592 RNA strand annealing activity(GO:0033592)
0.5 12.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.5 6.0 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.5 2.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.5 1.4 GO:0033149 FFAT motif binding(GO:0033149)
0.4 1.1 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.4 3.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.4 1.8 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.4 2.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.3 0.8 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.2 5.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 4.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 2.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 1.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 1.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 4.1 GO:0030957 Tat protein binding(GO:0030957)
0.2 2.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.6 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 1.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 4.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 0.9 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 2.8 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 10.9 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.2 1.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 3.5 GO:0004697 protein kinase C activity(GO:0004697)
0.1 1.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 2.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 3.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 3.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.8 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.5 GO:0044729 double-stranded methylated DNA binding(GO:0010385) hemi-methylated DNA-binding(GO:0044729)
0.1 2.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.6 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 1.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 2.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 2.2 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 4.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 7.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 8.6 GO:0008565 protein transporter activity(GO:0008565)
0.1 1.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.2 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 4.4 GO:0070888 E-box binding(GO:0070888)
0.1 1.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 1.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.5 GO:1901612 cardiolipin binding(GO:1901612)
0.1 1.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 2.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 2.6 GO:0005507 copper ion binding(GO:0005507)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 4.4 GO:0043130 ubiquitin binding(GO:0043130)
0.0 2.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 3.6 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 1.9 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 1.0 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 3.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 2.1 GO:0005506 iron ion binding(GO:0005506)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 7.7 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 4.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 4.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 3.1 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.2 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 2.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 4.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.3 5.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 3.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 4.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 3.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 2.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 3.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 8.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.2 3.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 2.2 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.2 2.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 4.4 REACTOME KINESINS Genes involved in Kinesins
0.1 1.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 3.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 4.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 4.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 4.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 2.9 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 2.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 1.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 0.8 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 5.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 3.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 4.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors