Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Pax8

Z-value: 0.72

Motif logo

logo of

Transcription factors associated with Pax8

Gene Symbol Gene ID Gene Info
Pax8
ENSMUSG00000026976.16 Pax8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pax8mm39_v1_chr2_-_24365607_24365619-0.382.3e-02Click!

Activity profile of Pax8 motif

Sorted Z-values of Pax8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_165591315 1.09 ENSMUST00000111432.10
Creg1
cellular repressor of E1A-stimulated genes 1
chr9_-_103107495 0.85 ENSMUST00000035158.16
Trf
transferrin
chr5_-_87739442 0.84 ENSMUST00000031201.9
Sult1e1
sulfotransferase family 1E, member 1
chr9_-_103107460 0.74 ENSMUST00000165296.8
ENSMUST00000112645.8
Trf
transferrin
chr4_+_103171002 0.57 ENSMUST00000035780.4
Oma1
OMA1 zinc metallopeptidase
chr6_-_138020409 0.57 ENSMUST00000111873.8
ENSMUST00000141280.3
Slc15a5
solute carrier family 15, member 5
chr1_-_136877277 0.52 ENSMUST00000168126.7
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chr5_-_151051000 0.42 ENSMUST00000202111.4
Stard13
StAR-related lipid transfer (START) domain containing 13
chr7_+_114367971 0.40 ENSMUST00000117543.3
ENSMUST00000151464.2
Insc
INSC spindle orientation adaptor protein
chr11_+_78389913 0.39 ENSMUST00000017488.5
Vtn
vitronectin
chr7_-_30560989 0.38 ENSMUST00000052700.6
Ffar1
free fatty acid receptor 1
chr6_+_127049865 0.36 ENSMUST00000000186.9
Fgf23
fibroblast growth factor 23
chr14_+_50683002 0.36 ENSMUST00000214792.2
Olfr740
olfactory receptor 740
chr2_+_164540421 0.35 ENSMUST00000017454.8
Spint4
serine protease inhibitor, Kunitz type 4
chr13_-_63712140 0.33 ENSMUST00000195756.6
Ptch1
patched 1
chr4_-_71676202 0.29 ENSMUST00000084489.3
Gm11232
predicted gene 11232
chr14_+_53828314 0.27 ENSMUST00000103654.3
Trav9-2
T cell receptor alpha variable 9-2
chr18_+_89215438 0.26 ENSMUST00000237110.2
Cd226
CD226 antigen
chr13_-_25454058 0.25 ENSMUST00000057866.13
Nrsn1
neurensin 1
chr18_-_66993567 0.25 ENSMUST00000057942.4
Mc4r
melanocortin 4 receptor
chr1_+_6557455 0.24 ENSMUST00000140079.8
ENSMUST00000131494.8
St18
suppression of tumorigenicity 18
chr14_+_50876845 0.24 ENSMUST00000213127.2
Olfr745
olfactory receptor 745
chr5_+_107655487 0.24 ENSMUST00000143074.2
Gm42669
predicted gene 42669
chr18_+_69654992 0.24 ENSMUST00000201627.4
Tcf4
transcription factor 4
chr9_+_32027335 0.23 ENSMUST00000174641.8
Arhgap32
Rho GTPase activating protein 32
chr2_+_153684901 0.23 ENSMUST00000175856.3
Efcab8
EF-hand calcium binding domain 8
chr18_+_69654900 0.21 ENSMUST00000202057.4
Tcf4
transcription factor 4
chr9_-_108474757 0.21 ENSMUST00000193621.2
ENSMUST00000006853.11
P4htm
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr13_-_62668265 0.21 ENSMUST00000082203.7
Zfp934
zinc finger protein 934
chr11_-_69692542 0.21 ENSMUST00000011285.11
ENSMUST00000102585.2
Fgf11
fibroblast growth factor 11
chrX_+_81992467 0.20 ENSMUST00000114000.8
Dmd
dystrophin, muscular dystrophy
chrX_-_7439082 0.20 ENSMUST00000132788.2
Ppp1r3f
protein phosphatase 1, regulatory subunit 3F
chr5_+_91222470 0.19 ENSMUST00000031324.6
Ereg
epiregulin
chr4_-_57301475 0.19 ENSMUST00000130900.2
Ptpn3
protein tyrosine phosphatase, non-receptor type 3
chr1_+_65225886 0.18 ENSMUST00000097707.5
Pikfyve
phosphoinositide kinase, FYVE type zinc finger containing
chr1_+_149975782 0.18 ENSMUST00000035065.9
Ptgs2
prostaglandin-endoperoxide synthase 2
chr11_-_105346120 0.18 ENSMUST00000138977.8
Marchf10
membrane associated ring-CH-type finger 10
chr8_+_61108574 0.18 ENSMUST00000034066.4
Mfap3l
microfibrillar-associated protein 3-like
chr2_-_73605387 0.17 ENSMUST00000166199.9
Chn1
chimerin 1
chr2_+_85822163 0.17 ENSMUST00000050942.3
Olfr1031
olfactory receptor 1031
chr6_+_30610973 0.17 ENSMUST00000062758.11
Cpa5
carboxypeptidase A5
chr13_-_62924903 0.16 ENSMUST00000167516.3
Gm5141
predicted gene 5141
chr11_-_87788066 0.15 ENSMUST00000217095.2
ENSMUST00000215150.2
Olfr463
olfactory receptor 463
chr6_+_30611028 0.15 ENSMUST00000115138.8
Cpa5
carboxypeptidase A5
chr14_+_53220658 0.15 ENSMUST00000200548.2
Trav9d-4
T cell receptor alpha variable 9D-4
chr14_+_50741057 0.13 ENSMUST00000217437.2
ENSMUST00000213935.2
Olfr742
olfactory receptor 742
chr3_-_64417263 0.13 ENSMUST00000177184.9
Vmn2r5
vomeronasal 2, receptor 5
chr12_-_28632514 0.12 ENSMUST00000110917.2
ENSMUST00000020965.14
Allc
allantoicase
chr7_+_112341233 0.10 ENSMUST00000164363.9
Tead1
TEA domain family member 1
chr14_+_33675934 0.10 ENSMUST00000035695.10
Rbp3
retinol binding protein 3, interstitial
chr10_+_112151245 0.09 ENSMUST00000218445.2
Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr7_-_29605504 0.09 ENSMUST00000053521.15
Zfp27
zinc finger protein 27
chr12_-_114370581 0.09 ENSMUST00000191918.2
Ighv6-4
immunoglobulin heavy variable V6-4
chr1_+_74582044 0.08 ENSMUST00000113749.8
ENSMUST00000067916.13
ENSMUST00000113747.8
ENSMUST00000113750.8
Plcd4
phospholipase C, delta 4
chr2_+_128809268 0.08 ENSMUST00000110320.9
ENSMUST00000110319.3
Zc3h6
zinc finger CCCH type containing 6
chr7_-_78432774 0.07 ENSMUST00000032841.7
Mrpl46
mitochondrial ribosomal protein L46
chr4_+_119397710 0.07 ENSMUST00000160219.2
Foxj3
forkhead box J3
chr4_+_6191084 0.07 ENSMUST00000029907.6
Ubxn2b
UBX domain protein 2B
chr4_-_43429077 0.07 ENSMUST00000107929.10
ENSMUST00000107928.9
ENSMUST00000171134.9
ENSMUST00000052829.10
Fam166b
family with sequence similarity 166, member B
chr2_-_25471703 0.07 ENSMUST00000114217.3
ENSMUST00000191602.2
Ajm1
apical junction component 1
chr3_-_123029745 0.06 ENSMUST00000106426.8
Synpo2
synaptopodin 2
chr16_+_34605282 0.06 ENSMUST00000023538.9
Mylk
myosin, light polypeptide kinase
chr3_-_123029782 0.05 ENSMUST00000106427.8
ENSMUST00000198584.2
Synpo2
synaptopodin 2
chr18_-_12254506 0.04 ENSMUST00000092075.5
Tmem241
transmembrane protein 241
chr6_-_68784692 0.02 ENSMUST00000103334.4
Igkv4-90
immunoglobulin kappa chain variable 4-90
chr18_-_60743169 0.02 ENSMUST00000115318.4
Synpo
synaptopodin
chr19_+_46064302 0.01 ENSMUST00000165017.2
ENSMUST00000223741.2
ENSMUST00000225780.2
Nolc1
nucleolar and coiled-body phosphoprotein 1
chr11_+_100900278 0.00 ENSMUST00000103110.10
ENSMUST00000044721.13
ENSMUST00000168757.9
Atp6v0a1
ATPase, H+ transporting, lysosomal V0 subunit A1
chr14_+_53100756 0.00 ENSMUST00000103616.5
ENSMUST00000186370.2
Trav15d-1-dv6d-1
T cell receptor alpha variable 15D-1-DV6D-1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0006711 estrogen catabolic process(GO:0006711)
0.2 1.6 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 0.6 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.4 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.2 GO:0021629 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.3 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.4 GO:0097421 smooth muscle cell-matrix adhesion(GO:0061302) liver regeneration(GO:0097421)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.3 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.0 0.2 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 GO:0097433 dense body(GO:0097433)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.8 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.3 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development