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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Pbx2

Z-value: 1.65

Motif logo

Transcription factors associated with Pbx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000034673.15 Pbx2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pbx2mm39_v1_chr17_+_34811217_34811303-0.811.5e-09Click!

Activity profile of Pbx2 motif

Sorted Z-values of Pbx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pbx2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_61972348 24.16 ENSMUST00000074018.4
major urinary protein 20
chr13_-_24098981 9.57 ENSMUST00000110407.4
solute carrier family 17 (sodium phosphate), member 4
chr13_-_24098951 8.91 ENSMUST00000021769.16
solute carrier family 17 (sodium phosphate), member 4
chr7_-_46392403 8.83 ENSMUST00000128088.4
serum amyloid A 1
chr7_+_46401214 7.10 ENSMUST00000210769.2
ENSMUST00000210272.2
ENSMUST00000075982.4
serum amyloid A 2
chr6_-_3988900 5.42 ENSMUST00000183682.3
tissue factor pathway inhibitor 2
chr4_-_96552349 5.17 ENSMUST00000030299.8
cytochrome P450, family 2, subfamily j, polypeptide 5
chr3_-_107851021 5.15 ENSMUST00000106684.8
ENSMUST00000106685.9
glutathione S-transferase, mu 6
chrX_-_8059597 5.10 ENSMUST00000143223.2
ENSMUST00000033509.15
phenylalkylamine Ca2+ antagonist (emopamil) binding protein
chr3_-_107850707 4.89 ENSMUST00000106681.3
glutathione S-transferase, mu 6
chr5_-_87572060 4.78 ENSMUST00000072818.6
UDP glucuronosyltransferase 2 family, polypeptide B38
chr5_-_87288177 4.40 ENSMUST00000067790.7
UDP glucuronosyltransferase 2 family, polypeptide B5
chr2_-_62242562 4.40 ENSMUST00000047812.8
dipeptidylpeptidase 4
chr6_-_3988835 4.30 ENSMUST00000203257.2
tissue factor pathway inhibitor 2
chr3_+_130411097 3.99 ENSMUST00000166187.8
ENSMUST00000072271.13
ethanolamine phosphate phospholyase
chr7_+_51537645 3.66 ENSMUST00000208711.2
growth arrest specific 2
chr8_-_95422851 3.22 ENSMUST00000034227.6
plasma membrane proteolipid
chr19_+_39980868 3.19 ENSMUST00000049178.3
cytochrome P450, family 2. subfamily c, polypeptide 37
chr13_+_4099001 3.08 ENSMUST00000118717.10
aldo-keto reductase family 1, member C14
chr4_+_140970161 2.97 ENSMUST00000138096.8
ENSMUST00000006618.9
ENSMUST00000125392.8
Rho guanine nucleotide exchange factor (GEF) 19
chr2_-_34951443 2.92 ENSMUST00000028233.7
hemolytic complement
chr3_+_122688721 2.77 ENSMUST00000023820.6
fatty acid binding protein 2, intestinal
chrM_+_11735 2.76 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chr6_-_127086480 2.64 ENSMUST00000039913.9
Trp53 induced glycolysis regulatory phosphatase
chr11_+_70104736 2.58 ENSMUST00000171032.8
solute carrier family 16 (monocarboxylic acid transporters), member 11
chr11_-_109986763 2.39 ENSMUST00000046223.14
ENSMUST00000106664.10
ENSMUST00000106662.2
ATP-binding cassette, sub-family A (ABC1), member 8a
chr11_+_97576619 2.35 ENSMUST00000107584.8
ENSMUST00000107585.9
CDGSH iron sulfur domain 3
chr12_+_76302064 2.25 ENSMUST00000021443.7
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
chr1_+_155911136 2.19 ENSMUST00000111757.10
torsin A interacting protein 2
chr12_+_76302145 2.19 ENSMUST00000220046.2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
chr1_+_88066086 2.16 ENSMUST00000014263.6
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr6_+_8259405 2.02 ENSMUST00000160705.8
ENSMUST00000159433.8
UMAP1-MVP12 associated (UMA) domain containing 1
chr11_-_115078653 1.99 ENSMUST00000103041.8
N-acetyltransferase 9 (GCN5-related, putative)
chr6_+_8259379 1.97 ENSMUST00000162034.8
UMAP1-MVP12 associated (UMA) domain containing 1
chr6_+_124281607 1.93 ENSMUST00000032234.5
ENSMUST00000112541.8
CD163 antigen
chr6_+_8259288 1.91 ENSMUST00000159335.8
UMAP1-MVP12 associated (UMA) domain containing 1
chr19_-_3625698 1.90 ENSMUST00000172362.3
ENSMUST00000025846.16
ENSMUST00000226109.2
ENSMUST00000113997.9
protein phosphatase 6, regulatory subunit 3
chr2_-_75768752 1.83 ENSMUST00000099996.5
tetratricopeptide repeat domain 30B
chrX_-_36137764 1.80 ENSMUST00000047486.6
RIKEN cDNA C330007P06 gene
chr11_+_97576724 1.72 ENSMUST00000107583.3
CDGSH iron sulfur domain 3
chr3_-_65300000 1.69 ENSMUST00000029414.12
signal sequence receptor, gamma
chr15_+_92495007 1.65 ENSMUST00000035399.10
PDZ domain containing RING finger 4
chr13_-_86194889 1.60 ENSMUST00000131011.2
cytochrome c oxidase subunit 7C
chr10_-_62486948 1.57 ENSMUST00000020270.6
DExD box helicase 50
chr1_-_80191649 1.54 ENSMUST00000058748.2
family with sequence similarity 124, member B
chr12_+_44268134 1.53 ENSMUST00000122902.8
patatin-like phospholipase domain containing 8
chr11_-_60243695 1.53 ENSMUST00000095254.12
ENSMUST00000102683.11
ENSMUST00000093048.13
ENSMUST00000093046.13
ENSMUST00000064019.15
ENSMUST00000102682.5
target of myb1-like 2 (chicken)
chr19_+_8897732 1.41 ENSMUST00000096243.7
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr9_+_119170360 1.40 ENSMUST00000039784.12
acetyl-Coenzyme A acyltransferase 1A
chr11_-_96720738 1.40 ENSMUST00000107657.8
ENSMUST00000081775.12
nuclear factor, erythroid derived 2,-like 1
chr11_-_31621727 1.38 ENSMUST00000109415.2
biorientation of chromosomes in cell division 1
chr17_+_85265420 1.38 ENSMUST00000080217.14
ENSMUST00000112304.10
protein phosphatase 1B, magnesium dependent, beta isoform
chr5_-_25047577 1.32 ENSMUST00000030787.9
Ras homolog enriched in brain
chr8_-_41507808 1.30 ENSMUST00000093534.11
mitochondrial tumor suppressor 1
chr6_+_8259328 1.28 ENSMUST00000159378.8
UMAP1-MVP12 associated (UMA) domain containing 1
chr1_-_169796709 1.26 ENSMUST00000027989.13
ENSMUST00000111353.4
hydroxysteroid (17-beta) dehydrogenase 7
chr5_+_144192033 1.23 ENSMUST00000056578.7
brain protein I3
chr18_+_3383230 1.20 ENSMUST00000162301.8
ENSMUST00000161317.2
cullin 2
chrX_+_37689503 1.19 ENSMUST00000000365.3
malignant T cell amplified sequence 1
chr7_-_3298243 1.17 ENSMUST00000108653.4
NLR family, pyrin domain containing 12
chr2_-_177567397 1.17 ENSMUST00000108934.9
ENSMUST00000081529.11
zinc finger protein 972
chr1_+_136552639 1.14 ENSMUST00000047734.15
ENSMUST00000112046.2
zinc finger protein 281
chr3_+_20011201 1.13 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
ceruloplasmin
chr3_-_65299967 1.05 ENSMUST00000119896.2
signal sequence receptor, gamma
chr3_+_20011251 1.05 ENSMUST00000108328.8
ceruloplasmin
chr7_+_29607917 1.02 ENSMUST00000186475.2
zinc finger protein 383
chr9_-_108140925 0.98 ENSMUST00000171412.7
ENSMUST00000195429.6
ENSMUST00000080435.9
dystroglycan 1
chr1_+_44158111 0.96 ENSMUST00000155917.8
basic, immunoglobulin-like variable motif containing
chr7_-_12829100 0.88 ENSMUST00000209822.3
ENSMUST00000235753.2
vomeronasal 1 receptor 85
chr7_+_133239414 0.87 ENSMUST00000128901.9
erythroid differentiation regulatory factor 1
chr12_-_83968507 0.87 ENSMUST00000222439.2
ENSMUST00000135962.8
ENSMUST00000155112.8
ENSMUST00000136848.8
ENSMUST00000126943.2
ENSMUST00000117217.8
NUMB endocytic adaptor protein
chr4_-_150087587 0.87 ENSMUST00000084117.13
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr3_-_88679881 0.86 ENSMUST00000090945.5
synaptotagmin XI
chr15_-_100945261 0.83 ENSMUST00000222611.2
transmembrane and death domain 1
chr5_+_104318542 0.79 ENSMUST00000112771.2
dentin sialophosphoprotein
chr11_-_109986804 0.79 ENSMUST00000100287.9
ATP-binding cassette, sub-family A (ABC1), member 8a
chr1_-_85239791 0.75 ENSMUST00000162421.2
RIKEN cDNA C130026I21 gene
chr5_-_3697806 0.75 ENSMUST00000119783.2
ENSMUST00000007559.15
GATA zinc finger domain containing 1
chr7_+_43256593 0.74 ENSMUST00000120935.2
ENSMUST00000127765.8
ENSMUST00000032661.14
zinc finger protein 819
chr3_+_20111958 0.74 ENSMUST00000002502.12
helicase-like transcription factor
chr17_+_75742881 0.71 ENSMUST00000164192.9
RAS, guanyl releasing protein 3
chr3_+_29136449 0.71 ENSMUST00000146943.8
EGF-like and EMI domain containing 1
chr13_+_60749735 0.70 ENSMUST00000226059.2
ENSMUST00000077453.13
death associated protein kinase 1
chr14_+_53194239 0.69 ENSMUST00000199800.2
T cell receptor alpha variable 15D-2-DV6D-2
chr17_-_35265702 0.68 ENSMUST00000097338.11
mutS homolog 5
chr9_+_95441652 0.67 ENSMUST00000079597.7
progestin and adipoQ receptor family member IX
chr15_-_5137951 0.66 ENSMUST00000141020.2
caspase recruitment domain family, member 6
chr4_+_102843540 0.65 ENSMUST00000030248.12
ENSMUST00000125417.9
ENSMUST00000169211.3
dynein light chain Tctex-type 5
chr1_-_181992051 0.65 ENSMUST00000227629.2
ENSMUST00000227586.2
vomeronasal 1 receptor 1
chr8_+_91555449 0.65 ENSMUST00000109614.9
chromodomain helicase DNA binding protein 9
chr12_+_119278005 0.64 ENSMUST00000222784.2
metastasis associated in colon cancer 1
chr11_-_58504307 0.63 ENSMUST00000048801.8
LY6/PLAUR domain containing 8 like
chr1_+_60948149 0.63 ENSMUST00000027164.9
cytotoxic T-lymphocyte-associated protein 4
chr9_-_20371123 0.61 ENSMUST00000162438.2
zinc finger protein 26
chr18_-_23171713 0.60 ENSMUST00000081423.13
nucleolar protein 4
chrX_-_43879055 0.60 ENSMUST00000060481.9
DDB1 and CUL4 associated factor 12-like 1
chr6_-_13677928 0.59 ENSMUST00000203078.2
ENSMUST00000045235.8
base methyltransferase of 25S rRNA 2
chr1_-_155910546 0.58 ENSMUST00000169241.8
torsin A interacting protein 1
chr5_-_72893941 0.56 ENSMUST00000169534.6
TXK tyrosine kinase
chr2_-_101451383 0.56 ENSMUST00000090513.11
intraflagellar transport associated protein
chr11_-_99241924 0.55 ENSMUST00000017732.3
keratin 27
chr15_-_5137975 0.53 ENSMUST00000118365.3
caspase recruitment domain family, member 6
chr15_-_101471324 0.53 ENSMUST00000023714.5
keratin 90
chr4_-_118667141 0.52 ENSMUST00000084313.5
ENSMUST00000219094.2
olfactory receptor 1335
chr14_+_123897383 0.52 ENSMUST00000049681.14
integrin, beta-like 1
chr1_+_134487928 0.52 ENSMUST00000112198.3
lysine (K)-specific demethylase 5B
chr1_+_169756217 0.51 ENSMUST00000094348.4
coiled-coil domain containing 190
chr9_-_58277734 0.51 ENSMUST00000040217.6
TBC1 domain family, member 21
chr7_+_119289249 0.51 ENSMUST00000047045.10
acyl-CoA synthetase medium-chain family member 4
chr13_-_99653045 0.50 ENSMUST00000064762.6
microtubule-associated protein 1B
chr4_+_147576874 0.50 ENSMUST00000105721.9
zinc finger protein 982
chr2_-_136727599 0.50 ENSMUST00000231720.2
novel protein
chrX_+_36920563 0.49 ENSMUST00000096454.2
reproductive homeobox 7A
chr2_-_151510453 0.48 ENSMUST00000180195.8
ENSMUST00000096439.4
RAD21-like (S. pombe)
chr2_-_88590348 0.48 ENSMUST00000131038.4
ENSMUST00000213138.3
olfactory receptor 1199
chr3_+_145823205 0.47 ENSMUST00000140214.3
mucolipin 3
chr8_-_84963653 0.46 ENSMUST00000039480.7
zinc finger SWIM-type containing 4
chr14_+_63284438 0.45 ENSMUST00000067990.8
ENSMUST00000111203.2
defensin beta 42
chr1_+_134487893 0.45 ENSMUST00000047714.14
lysine (K)-specific demethylase 5B
chr17_-_52140305 0.44 ENSMUST00000133574.8
special AT-rich sequence binding protein 1
chr19_-_5168251 0.44 ENSMUST00000113728.8
ENSMUST00000113727.8
ENSMUST00000025798.13
kinesin light chain 2
chr8_-_55177510 0.44 ENSMUST00000175915.8
WD repeat domain 17
chr19_-_11833365 0.44 ENSMUST00000079875.4
olfactory receptor 1418
chrX_-_36986109 0.41 ENSMUST00000115156.2
reproductive homeobox 7B
chr1_+_157353696 0.41 ENSMUST00000111700.8
SEC16 homolog B (S. cerevisiae)
chr3_-_152687877 0.39 ENSMUST00000044278.6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr13_-_43324937 0.39 ENSMUST00000222160.2
ENSMUST00000179852.9
ENSMUST00000021797.9
TBC1 domain family, member 7
chr11_-_99313078 0.39 ENSMUST00000017741.4
keratin 12
chr1_-_138770167 0.39 ENSMUST00000112026.4
ENSMUST00000019374.14
LIM homeobox protein 9
chr7_+_106737534 0.39 ENSMUST00000213367.3
ENSMUST00000214819.3
ENSMUST00000216871.3
ENSMUST00000215284.3
ENSMUST00000209942.2
olfactory receptor 716
chr17_-_28584182 0.38 ENSMUST00000041819.14
tubby like protein 1
chr3_+_152052102 0.38 ENSMUST00000117492.9
ENSMUST00000026507.13
ENSMUST00000197748.5
ubiquitin specific peptidase 33
chr11_+_88964667 0.37 ENSMUST00000100619.11
predicted gene 525
chr6_+_40468167 0.37 ENSMUST00000064932.6
taste receptor, type 2, member 137
chr4_+_146033882 0.37 ENSMUST00000105730.2
ENSMUST00000091878.6
zinc finger protein 987
chr14_+_53574579 0.37 ENSMUST00000179580.3
T cell receptor alpha variable 13N-3
chr6_-_67743756 0.36 ENSMUST00000103306.2
immunoglobulin kappa variable 1-131
chr19_-_32080496 0.36 ENSMUST00000235213.2
ENSMUST00000236504.2
N-acylsphingosine amidohydrolase 2
chr7_-_121700958 0.35 ENSMUST00000139456.2
ENSMUST00000106471.9
ENSMUST00000123296.8
ENSMUST00000033157.10
NADH:ubiquinone oxidoreductase subunit AB1
chr7_+_99384352 0.34 ENSMUST00000098264.2
olfactory receptor 520
chr7_-_27749453 0.34 ENSMUST00000140053.3
ENSMUST00000032824.10
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr16_-_37205302 0.33 ENSMUST00000114781.8
ENSMUST00000114780.8
syntaxin binding protein 5-like
chr6_-_129303659 0.33 ENSMUST00000203159.2
C-type lectin domain family 2, member m
chr4_-_59138983 0.32 ENSMUST00000107547.2
shortage in chiasmata 1
chr13_-_21798192 0.32 ENSMUST00000051874.6
olfactory receptor 1362
chr7_+_18451998 0.32 ENSMUST00000051973.9
ENSMUST00000208221.2
ENSMUST00000108481.8
pregnancy-specific glycoprotein 22
chr7_-_18165959 0.30 ENSMUST00000019291.7
pregnancy-specific glycoprotein 28
chr1_+_60948307 0.29 ENSMUST00000097720.4
cytotoxic T-lymphocyte-associated protein 4
chr9_-_6269846 0.29 ENSMUST00000051706.6
DNA-damage inducible 1
chr3_-_98417351 0.29 ENSMUST00000179429.6
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4
chrX_-_20955370 0.28 ENSMUST00000040667.13
zinc finger protein 300
chr9_-_80347482 0.27 ENSMUST00000085289.12
ENSMUST00000185068.2
ENSMUST00000113250.10
interphotoreceptor matrix proteoglycan 1
chr18_+_46983105 0.26 ENSMUST00000025358.4
ENSMUST00000234519.2
laeverin
chr1_+_164103127 0.26 ENSMUST00000027867.7
coiled-coil domain containing 181
chr2_-_175017664 0.24 ENSMUST00000109054.3
predicted gene 14443
chr17_+_9068805 0.24 ENSMUST00000115720.8
phosphodiesterase 10A
chr2_-_89555356 0.24 ENSMUST00000216203.2
ENSMUST00000213196.2
olfactory receptor 1252
chr4_+_146599377 0.23 ENSMUST00000140089.7
ENSMUST00000179175.3
zinc finger protein 981
chr4_-_146993984 0.23 ENSMUST00000238583.2
ENSMUST00000049821.4
predicted gene, 21411
chr15_-_98118858 0.23 ENSMUST00000142443.8
ENSMUST00000170618.8
predicted gene 44579
olfactory receptor 287
chrX_-_121307036 0.23 ENSMUST00000079490.6
nucleosome assembly protein 1-like 3
chr7_-_103291882 0.23 ENSMUST00000213536.2
ENSMUST00000216570.2
olfactory receptor 622
chr9_-_70841881 0.22 ENSMUST00000214995.2
lipase, hepatic
chr7_+_6048160 0.22 ENSMUST00000037728.13
ENSMUST00000121583.2
NLR family, pyrin domain containing 4C
chr11_+_58311921 0.21 ENSMUST00000013797.3
RIKEN cDNA 1810065E05 gene
chr16_-_37205277 0.21 ENSMUST00000114787.8
ENSMUST00000114782.8
ENSMUST00000114775.8
syntaxin binding protein 5-like
chr4_-_147787010 0.20 ENSMUST00000117638.2
zinc finger protein 534
chr4_+_145397238 0.20 ENSMUST00000105738.9
zinc finger protein 980
chr13_-_25454058 0.20 ENSMUST00000057866.13
neurensin 1
chr9_+_92191415 0.20 ENSMUST00000150594.8
ENSMUST00000098477.8
RIKEN cDNA 1700057G04 gene
chr4_+_147056433 0.19 ENSMUST00000146688.3
zinc finger protein 989
chr9_+_38686470 0.18 ENSMUST00000071681.4
olfactory receptor 921
chrX_-_91643178 0.18 ENSMUST00000113955.2
MAGE family member B18
chr2_-_57942844 0.18 ENSMUST00000090940.6
ermin, ERM-like protein
chr2_+_29014106 0.18 ENSMUST00000129544.8
senataxin
chr12_+_103547657 0.18 ENSMUST00000190664.2
protein phosphatase 4, regulatory subunit 4
chr6_+_78347636 0.17 ENSMUST00000204873.3
regenerating islet-derived 3 beta
chr6_+_41112064 0.17 ENSMUST00000103272.4
T cell receptor beta, variable 14
chrX_+_72108393 0.17 ENSMUST00000060418.8
paraneoplastic antigen MA3
chr4_+_146093394 0.17 ENSMUST00000168483.9
zinc finger protein 600
chr3_-_151455514 0.17 ENSMUST00000029671.9
interferon-induced protein 44
chr4_+_12089373 0.16 ENSMUST00000095143.9
ENSMUST00000063839.6
RNA binding motif protein 12 B2
chr5_-_122492223 0.16 ENSMUST00000117263.8
ENSMUST00000049009.7
RAD9 checkpoint clamp component B
chr6_-_69920632 0.16 ENSMUST00000198880.5
ENSMUST00000103371.3
immunoglobulin kappa chain variable 12-38
chr15_+_82230155 0.16 ENSMUST00000023086.15
single-pass membrane protein with aspartate rich tail 1
chrX_+_111150171 0.16 ENSMUST00000164272.3
ENSMUST00000132037.2
RIKEN cDNA 4933403O08 gene
chr2_-_113588983 0.15 ENSMUST00000099575.4
gremlin 1, DAN family BMP antagonist
chr15_+_77392466 0.15 ENSMUST00000172191.3
apolipoprotein L 11a
chr12_-_55349760 0.15 ENSMUST00000021410.10
protein phosphatase 2, regulatory subunit B'', gamma
chr2_+_128809268 0.15 ENSMUST00000110320.9
ENSMUST00000110319.3
zinc finger CCCH type containing 6
chr4_+_147106307 0.15 ENSMUST00000075775.6
reduced expression 2
chr1_+_15875846 0.13 ENSMUST00000188371.7
ENSMUST00000027057.8
telomeric repeat binding factor 1
chr2_-_4656870 0.13 ENSMUST00000192470.2
ENSMUST00000035721.14
ENSMUST00000152362.7
pre-mRNA processing factor 18
chr16_-_50151350 0.13 ENSMUST00000114488.8
bobby sox HMG box containing
chr16_-_93400691 0.13 ENSMUST00000023669.14
ENSMUST00000233931.2
ENSMUST00000154355.3
SET domain containing 4
chr10_+_81442137 0.12 ENSMUST00000119492.2
cDNA sequence BC025920
chr19_-_32038838 0.12 ENSMUST00000096119.5
N-acylsphingosine amidohydrolase 2
chr5_+_8710059 0.12 ENSMUST00000047753.5
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
chr5_-_151510389 0.12 ENSMUST00000165928.4
vomeronasal 2, receptor 18
chr17_-_35334404 0.11 ENSMUST00000172854.2
ENSMUST00000062657.5
lymphocyte antigen 6 complex, locus G5B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 24.2 GO:0008355 olfactory learning(GO:0008355)
1.7 5.2 GO:2000863 positive regulation of estrogen secretion(GO:2000863)
1.1 4.4 GO:0000105 histidine biosynthetic process(GO:0000105) 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.9 2.6 GO:1902689 negative regulation of NAD metabolic process(GO:1902689) negative regulation of glucose catabolic process to lactate via pyruvate(GO:1904024)
0.9 4.4 GO:0036343 psychomotor behavior(GO:0036343)
0.7 2.9 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.5 1.5 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.5 1.0 GO:2000861 estrogen secretion(GO:0035937) regulation of estrogen secretion(GO:2000861)
0.4 1.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3 1.0 GO:0021682 nerve maturation(GO:0021682)
0.3 3.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3 0.9 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.3 18.0 GO:0006953 acute-phase response(GO:0006953)
0.3 1.4 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.3 0.8 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 0.9 GO:1905154 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.2 1.2 GO:0002188 translation reinitiation(GO:0002188)
0.2 1.4 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.2 2.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 2.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 0.9 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 2.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 1.3 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 17.9 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 0.3 GO:2001201 regulation of transforming growth factor-beta secretion(GO:2001201)
0.1 1.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 3.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.6 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 6.4 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.1 2.2 GO:0046688 response to copper ion(GO:0046688)
0.1 0.5 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.2 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.1 0.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.2 GO:1900158 negative regulation of monocyte chemotaxis(GO:0090027) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.9 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.2 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.0 2.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.7 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.4 GO:0009249 protein lipoylation(GO:0009249)
0.0 1.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 1.4 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 9.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.4 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:2001025 positive regulation of response to drug(GO:2001025)
0.0 0.1 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 1.9 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.0 0.5 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.0 0.7 GO:0006301 postreplication repair(GO:0006301)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 1.1 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.6 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 1.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 1.2 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 3.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.5 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 2.6 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.0 GO:0030845 regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010924) positive regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010925) phospholipase C-inhibiting G-protein coupled receptor signaling pathway(GO:0030845) regulation of cell diameter(GO:0060305)
0.0 0.3 GO:0035634 response to stilbenoid(GO:0035634)
0.0 3.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 3.3 GO:0006869 lipid transport(GO:0006869)
0.0 0.2 GO:0031573 DNA replication checkpoint(GO:0000076) intra-S DNA damage checkpoint(GO:0031573)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.4 GO:0071438 invadopodium membrane(GO:0071438)
0.4 16.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 2.9 GO:0005579 membrane attack complex(GO:0005579)
0.3 2.8 GO:0045179 apical cortex(GO:0045179)
0.1 1.2 GO:0030891 VCB complex(GO:0030891)
0.1 3.2 GO:0043218 compact myelin(GO:0043218)
0.1 0.2 GO:0033269 internode region of axon(GO:0033269)
0.1 1.0 GO:0016011 dystroglycan complex(GO:0016011)
0.1 0.5 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 0.9 GO:0032009 early phagosome(GO:0032009)
0.0 1.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 2.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 8.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 2.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 9.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0070187 telosome(GO:0070187)
0.0 28.2 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.9 GO:0030136 clathrin-coated vesicle(GO:0030136)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 24.2 GO:0005186 pheromone activity(GO:0005186)
1.3 4.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
1.2 18.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
1.1 4.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.7 5.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.5 3.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.5 1.4 GO:0008775 acetate CoA-transferase activity(GO:0008775)
0.4 15.9 GO:0042056 chemoattractant activity(GO:0042056)
0.3 12.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 2.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 0.9 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.3 2.6 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2 1.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 8.4 GO:0070330 aromatase activity(GO:0070330)
0.2 4.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 3.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 2.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 10.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 1.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.0 GO:0043237 laminin-1 binding(GO:0043237)
0.1 4.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.4 GO:0031177 phosphopantetheine binding(GO:0031177)
0.1 2.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.6 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.1 9.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 2.8 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.2 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.9 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 2.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 2.7 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 3.0 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 3.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 1.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 2.0 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 1.4 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 3.7 GO:0008017 microtubule binding(GO:0008017)
0.0 2.1 GO:0004386 helicase activity(GO:0004386)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.0 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 4.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 6.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 4.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 3.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 4.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 2.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism