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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Pgr_Nr3c1

Z-value: 1.18

Motif logo

Transcription factors associated with Pgr_Nr3c1

Gene Symbol Gene ID Gene Info
ENSMUSG00000031870.17 Pgr
ENSMUSG00000024431.16 Nr3c1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pgrmm39_v1_chr9_+_8900460_8900503-0.202.3e-01Click!
Nr3c1mm39_v1_chr18_-_39623698_396237710.134.4e-01Click!

Activity profile of Pgr_Nr3c1 motif

Sorted Z-values of Pgr_Nr3c1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pgr_Nr3c1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_30623592 16.55 ENSMUST00000217812.2
ENSMUST00000074671.9
hepcidin antimicrobial peptide 2
chr6_+_125297596 6.09 ENSMUST00000176655.8
ENSMUST00000176110.8
sodium channel, nonvoltage-gated 1 alpha
chr16_-_10360893 5.18 ENSMUST00000184863.8
ENSMUST00000038281.6
dexamethasone-induced transcript
chr6_-_124519240 4.06 ENSMUST00000159463.8
ENSMUST00000162844.2
ENSMUST00000160505.8
ENSMUST00000162443.8
complement component 1, s subcomponent 1
chr1_+_88066086 3.91 ENSMUST00000014263.6
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr17_-_34962823 3.44 ENSMUST00000069507.9
complement component 4B (Chido blood group)
chr15_+_25843225 3.25 ENSMUST00000022881.15
reticulophagy regulator 1
chrX_+_100427331 3.15 ENSMUST00000119190.2
gap junction protein, beta 1
chr6_+_42222841 2.97 ENSMUST00000031897.8
glutathione S-transferase kappa 1
chr13_+_25127127 2.96 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr11_-_3881960 2.64 ENSMUST00000109990.8
transcobalamin 2
chr11_-_95966407 2.56 ENSMUST00000107686.8
ENSMUST00000107684.2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
chr11_-_3881789 2.54 ENSMUST00000109992.8
ENSMUST00000109988.2
transcobalamin 2
chr10_-_108846816 2.53 ENSMUST00000105276.8
ENSMUST00000064054.14
synaptotagmin I
chr6_+_125298296 2.51 ENSMUST00000081440.14
sodium channel, nonvoltage-gated 1 alpha
chr11_-_3881995 2.26 ENSMUST00000020710.11
ENSMUST00000109989.10
ENSMUST00000109991.8
ENSMUST00000109993.9
transcobalamin 2
chr18_+_20798337 2.09 ENSMUST00000075312.5
transthyretin
chr6_-_116050081 1.94 ENSMUST00000173548.3
transmembrane and coiled coil domains 1
chr5_-_66238313 1.94 ENSMUST00000202700.4
ENSMUST00000094757.9
ENSMUST00000113724.6
RNA binding motif protein 47
chr5_+_30971915 1.89 ENSMUST00000031058.15
microtubule-associated protein, RP/EB family, member 3
chr11_+_117716711 1.88 ENSMUST00000073388.13
arylformamidase
chr11_-_95966477 1.85 ENSMUST00000090541.12
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
chr19_-_6134703 1.82 ENSMUST00000161548.8
zinc finger like protein 1
chr11_+_117716759 1.78 ENSMUST00000149668.2
arylformamidase
chr6_-_35303057 1.73 ENSMUST00000051176.9
family with sequence similarity 180, member A
chr10_-_67972401 1.72 ENSMUST00000218532.2
AT rich interactive domain 5B (MRF1-like)
chr3_-_95811993 1.66 ENSMUST00000147962.3
ENSMUST00000036181.15
carbonic anhydrase 14
chr5_+_30972067 1.63 ENSMUST00000200692.4
microtubule-associated protein, RP/EB family, member 3
chr4_-_119279551 1.56 ENSMUST00000106316.2
ENSMUST00000030385.13
phosphopantothenoylcysteine synthetase
chr5_-_121710768 1.55 ENSMUST00000200541.5
aldehyde dehydrogenase 2, mitochondrial
chr6_-_138056914 1.51 ENSMUST00000171804.4
solute carrier family 15, member 5
chr6_-_47790272 1.45 ENSMUST00000077290.9
protein disulfide isomerase associated 4
chr3_-_97775557 1.39 ENSMUST00000107038.6
phosphodiesterase 4D interacting protein (myomegalin)
chr13_+_58956495 1.19 ENSMUST00000225950.2
ENSMUST00000225583.2
neurotrophic tyrosine kinase, receptor, type 2
chr8_-_3767547 1.09 ENSMUST00000058040.7
C-type lectin domain family 4, member g
chr5_+_65288418 1.05 ENSMUST00000101191.10
ENSMUST00000204348.3
kelch-like 5
chr2_-_103133503 1.05 ENSMUST00000111176.9
ets homologous factor
chr3_-_57599956 1.05 ENSMUST00000238789.2
ENSMUST00000197088.5
ENSMUST00000099091.4
ankrin repeat and ubiquitin domain containing 1
chr3_+_29568055 1.04 ENSMUST00000140288.2
EGF-like and EMI domain containing 1
chr10_-_127504416 1.03 ENSMUST00000129252.2
Ngfi-A binding protein 2
chr3_-_89294430 1.02 ENSMUST00000107433.8
zinc finger and BTB domain containing 7B
chr7_+_30252687 1.02 ENSMUST00000044048.8
heat shock protein, alpha-crystallin-related, B6
chr15_-_81283795 1.00 ENSMUST00000023039.15
suppression of tumorigenicity 13
chr2_-_103133524 0.94 ENSMUST00000090475.10
ets homologous factor
chr2_+_91086489 0.92 ENSMUST00000154959.8
ENSMUST00000059566.11
protein kinase C and casein kinase substrate in neurons 3
chr19_-_6134903 0.91 ENSMUST00000160977.8
ENSMUST00000159859.2
ENSMUST00000025707.9
ENSMUST00000160712.8
ENSMUST00000237738.2
zinc finger like protein 1
chr17_+_43671314 0.86 ENSMUST00000226087.2
adhesion G protein-coupled receptor F5
chr14_-_124914516 0.84 ENSMUST00000095529.10
fibroblast growth factor 14
chr16_+_34815177 0.84 ENSMUST00000231589.2
myosin, light polypeptide kinase
chr3_-_133250129 0.84 ENSMUST00000196398.5
ENSMUST00000098603.8
tet methylcytosine dioxygenase 2
chr5_-_24806960 0.83 ENSMUST00000030791.12
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_-_71692320 0.79 ENSMUST00000186940.7
ENSMUST00000188894.7
ENSMUST00000188674.7
ENSMUST00000189821.7
ENSMUST00000187938.7
ENSMUST00000190780.7
ENSMUST00000186736.2
ENSMUST00000055226.13
ENSMUST00000186129.7
fibronectin 1
chr8_+_124100588 0.76 ENSMUST00000211932.2
ENSMUST00000212569.2
transcription factor 25 (basic helix-loop-helix)
chr2_-_63014622 0.76 ENSMUST00000075052.10
ENSMUST00000112454.8
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr15_-_89361571 0.76 ENSMUST00000165199.8
arylsulfatase A
chr15_-_81284244 0.75 ENSMUST00000172107.8
ENSMUST00000169204.2
ENSMUST00000163382.2
suppression of tumorigenicity 13
chr2_+_91086299 0.74 ENSMUST00000134699.8
protein kinase C and casein kinase substrate in neurons 3
chr16_+_43184191 0.68 ENSMUST00000156367.8
zinc finger and BTB domain containing 20
chr7_-_126184935 0.68 ENSMUST00000084589.11
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr11_-_121410152 0.67 ENSMUST00000092298.6
zinc finger protein 750
chr14_-_78545472 0.67 ENSMUST00000022592.8
tumor necrosis factor (ligand) superfamily, member 11
chr11_-_48707763 0.66 ENSMUST00000140800.2
tripartite motif-containing 41
chr15_+_81284333 0.64 ENSMUST00000163754.9
ENSMUST00000041609.11
X-prolyl aminopeptidase 3, mitochondrial
chr4_+_99952988 0.64 ENSMUST00000039630.6
receptor tyrosine kinase-like orphan receptor 1
chr19_-_55304392 0.61 ENSMUST00000224291.2
ENSMUST00000225495.2
ENSMUST00000076891.7
ENSMUST00000224897.2
zinc finger, DHHC domain containing 6
chr6_-_93769426 0.59 ENSMUST00000204788.2
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr15_-_50753792 0.59 ENSMUST00000185183.2
transcriptional repressor GATA binding 1
chr15_-_65784246 0.59 ENSMUST00000060522.11
otoconin 90
chr8_+_124100492 0.58 ENSMUST00000212571.2
ENSMUST00000212470.2
ENSMUST00000108840.4
ENSMUST00000057934.10
transcription factor 25 (basic helix-loop-helix)
chr9_+_72832904 0.58 ENSMUST00000038489.6
pygopus 1
chr15_-_65784103 0.57 ENSMUST00000079776.14
otoconin 90
chr2_-_77000878 0.56 ENSMUST00000111833.3
coiled-coil domain containing 141
chr17_-_25300112 0.54 ENSMUST00000024984.7
transmembrane protein 204
chr19_+_4560500 0.54 ENSMUST00000068004.13
ENSMUST00000224726.3
pyruvate carboxylase
chr2_-_63014514 0.53 ENSMUST00000112452.2
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr10_-_107330580 0.52 ENSMUST00000044210.5
myogenic factor 6
chr2_-_126718037 0.51 ENSMUST00000028843.12
transient receptor potential cation channel, subfamily M, member 7
chr6_+_17491231 0.51 ENSMUST00000080469.12
met proto-oncogene
chr3_+_87704258 0.49 ENSMUST00000029711.9
ENSMUST00000107582.3
insulin receptor-related receptor
chr17_-_46342739 0.48 ENSMUST00000024747.14
vascular endothelial growth factor A
chr15_-_98796373 0.48 ENSMUST00000229775.2
ENSMUST00000023737.6
desert hedgehog
chr4_-_91264670 0.47 ENSMUST00000107109.9
ENSMUST00000107111.9
ENSMUST00000107120.8
ELAV like RNA binding protein 1
chr14_-_69969959 0.46 ENSMUST00000036381.10
charged multivesicular body protein 7
chr9_+_46184362 0.46 ENSMUST00000156440.8
ENSMUST00000114552.4
ZPR1 zinc finger
chr9_-_119548388 0.46 ENSMUST00000213392.2
sodium channel, voltage-gated, type X, alpha
chr9_+_103917821 0.46 ENSMUST00000216593.2
ENSMUST00000147249.3
nephronophthisis 3 (adolescent)
predicted gene 28305
chr11_+_83599841 0.45 ENSMUST00000001009.14
WAP four-disulfide core domain 18
chr11_-_100830366 0.44 ENSMUST00000127638.8
signal transducer and activator of transcription 3
chr16_-_5040125 0.44 ENSMUST00000050160.6
expressed sequence AU021092
chr16_+_43067641 0.42 ENSMUST00000079441.13
ENSMUST00000114691.8
zinc finger and BTB domain containing 20
chr7_+_28834391 0.42 ENSMUST00000160194.8
RAS guanyl releasing protein 4
chr8_+_47192767 0.42 ENSMUST00000034041.9
ENSMUST00000208507.2
ENSMUST00000207105.2
interferon regulatory factor 2
chr6_+_41139948 0.41 ENSMUST00000103275.4
T cell receptor beta, variable 17
chr4_-_91264727 0.41 ENSMUST00000107124.10
ELAV like RNA binding protein 1
chr11_+_88184872 0.41 ENSMUST00000037268.6
coiled-coil domain containing 182
chr13_-_101831020 0.40 ENSMUST00000185795.2
phosphoinositide-3-kinase regulatory subunit 1
chr6_-_87312681 0.40 ENSMUST00000204805.3
anthrax toxin receptor 1
chr6_+_125298168 0.38 ENSMUST00000176365.2
sodium channel, nonvoltage-gated 1 alpha
chr2_-_126718129 0.36 ENSMUST00000103224.10
transient receptor potential cation channel, subfamily M, member 7
chr11_-_48708159 0.35 ENSMUST00000047145.14
tripartite motif-containing 41
chr9_-_119548098 0.34 ENSMUST00000084787.6
sodium channel, voltage-gated, type X, alpha
chrX_+_158039107 0.33 ENSMUST00000148570.8
ribosomal protein S6 kinase polypeptide 3
chr14_+_123897383 0.33 ENSMUST00000049681.14
integrin, beta-like 1
chr6_-_54941673 0.32 ENSMUST00000203837.2
nucleotide-binding oligomerization domain containing 1
chr15_-_99603371 0.31 ENSMUST00000163472.3
predicted gene, 17349
chr7_+_26896401 0.30 ENSMUST00000155931.2
cDNA sequence BC024978
chr1_+_59669482 0.30 ENSMUST00000190490.2
predicted gene 973
chr6_-_72338379 0.30 ENSMUST00000130064.8
ring finger protein 181
chr8_+_47193275 0.30 ENSMUST00000207571.3
interferon regulatory factor 2
chr6_+_21949570 0.30 ENSMUST00000031680.10
ENSMUST00000115389.8
ENSMUST00000151473.8
inhibitor of growth family, member 3
chr12_-_75782406 0.29 ENSMUST00000220285.2
sphingosine-1-phosphate phosphatase 1
chr9_-_117080869 0.28 ENSMUST00000172564.3
RNA binding motif, single stranded interacting protein
chr11_-_78388560 0.28 ENSMUST00000061174.7
sterile alpha and HEAT/Armadillo motif containing 1
chr11_+_73244561 0.27 ENSMUST00000108465.4
olfactory receptor 20
chr10_+_127256192 0.27 ENSMUST00000171434.8
R3H domain containing 2
chr13_-_55979191 0.26 ENSMUST00000021968.7
paired-like homeodomain transcription factor 1
chrX_+_158038915 0.26 ENSMUST00000112492.8
ribosomal protein S6 kinase polypeptide 3
chr2_-_65397850 0.26 ENSMUST00000238483.2
ENSMUST00000100069.9
sodium channel, voltage-gated, type III, alpha
chr19_+_55304703 0.25 ENSMUST00000225529.2
ENSMUST00000223690.2
ENSMUST00000095950.3
vesicle transport through interaction with t-SNAREs 1A
chr7_-_109215960 0.25 ENSMUST00000077909.9
DENN domain containing 2B
chr11_+_83363905 0.23 ENSMUST00000021018.11
TATA-box binding protein associated factor 15
chr18_+_37822865 0.23 ENSMUST00000195112.2
protocadherin gamma subfamily B, 2
chr6_+_34686373 0.22 ENSMUST00000115021.8
caldesmon 1
chr4_+_134042423 0.21 ENSMUST00000105875.8
ENSMUST00000030638.7
tripartite motif-containing 63
chr2_-_77000936 0.21 ENSMUST00000164114.9
ENSMUST00000049544.14
coiled-coil domain containing 141
chr3_-_137773149 0.21 ENSMUST00000053318.4
predicted gene 5105
chr11_+_110956980 0.20 ENSMUST00000042970.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr17_-_48739874 0.19 ENSMUST00000046549.5
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr11_+_97732108 0.19 ENSMUST00000155954.3
ENSMUST00000164364.2
ENSMUST00000170806.2
RIKEN cDNA B230217C12 gene
chr19_+_53781721 0.19 ENSMUST00000162910.2
RNA binding motif protein 20
chr6_+_32027216 0.18 ENSMUST00000031778.6
RIKEN cDNA 1700012A03 gene
chr14_-_32186721 0.18 ENSMUST00000191501.2
solute carrier family 18 (vesicular monoamine), member 3
chr8_+_125302843 0.17 ENSMUST00000093033.6
ENSMUST00000133086.2
calpain 9
chr14_-_51433380 0.17 ENSMUST00000051274.2
angiogenin, ribonuclease A family, member 2
chr4_-_141125885 0.17 ENSMUST00000133676.3
ENSMUST00000042617.14
chloride channel, voltage-sensitive Ka
chr17_+_34863779 0.16 ENSMUST00000174796.2
FK506 binding protein-like
chr17_-_71153283 0.16 ENSMUST00000156484.2
TGFB-induced factor homeobox 1
chr11_+_69047815 0.15 ENSMUST00000036424.3
arachidonate 12-lipoxygenase, 12R type
chr16_+_93526987 0.15 ENSMUST00000227156.2
DOP1 leucine zipper like protein B
chr18_+_23548534 0.15 ENSMUST00000221880.2
ENSMUST00000220904.2
ENSMUST00000047954.15
dystrobrevin alpha
chr2_-_65397809 0.15 ENSMUST00000066432.12
sodium channel, voltage-gated, type III, alpha
chr8_+_47192911 0.15 ENSMUST00000208433.2
interferon regulatory factor 2
chr11_+_98277276 0.15 ENSMUST00000041301.8
phenylethanolamine-N-methyltransferase
chr1_-_57011595 0.15 ENSMUST00000042857.14
special AT-rich sequence binding protein 2
chr12_-_31763859 0.15 ENSMUST00000057783.6
ENSMUST00000236002.2
ENSMUST00000174480.3
ENSMUST00000176710.2
G protein-coupled receptor 22
chr4_+_99184137 0.14 ENSMUST00000094955.3
predicted gene 12689
chr1_-_139304832 0.14 ENSMUST00000198445.5
crumbs family member 1, photoreceptor morphogenesis associated
chr11_-_23845207 0.14 ENSMUST00000102863.3
ENSMUST00000020513.10
poly(A) polymerase gamma
chr16_-_92118313 0.13 ENSMUST00000062638.8
family with sequence similarity 243
chr14_-_23604866 0.13 ENSMUST00000212576.2
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr2_-_93826699 0.13 ENSMUST00000183110.2
predicted gene, 27027
chr2_+_79538124 0.13 ENSMUST00000090760.9
ENSMUST00000040863.11
ENSMUST00000111780.3
protein phosphatase 1, regulatory inhibitor subunit 1C
chr2_+_74552322 0.13 ENSMUST00000047904.4
homeobox D4
chr10_-_105410280 0.12 ENSMUST00000061506.9
transmembrane and tetratricopeptide repeat containing 2
chr4_+_136012019 0.11 ENSMUST00000130223.8
zinc finger protein 46
chr11_+_101315893 0.11 ENSMUST00000040561.6
RUN domain containing 1
chr8_-_68427217 0.11 ENSMUST00000098696.10
ENSMUST00000038959.16
ENSMUST00000093469.11
pleckstrin and Sec7 domain containing 3
chr7_-_74958121 0.11 ENSMUST00000085164.7
synaptic vesicle glycoprotein 2 b
chr12_-_73093953 0.10 ENSMUST00000050029.8
sine oculis-related homeobox 1
chr13_-_98773862 0.10 ENSMUST00000050389.5
transmembrane protein 174
chr16_-_59090028 0.10 ENSMUST00000099656.2
olfactory receptor 201
chr14_+_63235512 0.10 ENSMUST00000100492.5
defensin beta 47
chr14_+_55887661 0.09 ENSMUST00000226497.2
ENSMUST00000228041.2
testis-specific serine kinase 4
chr15_+_102862862 0.09 ENSMUST00000001701.4
homeobox C11
chr1_-_9818601 0.08 ENSMUST00000057438.7
valosin containing protein (p97)/p47 complex interacting protein 1
chr5_+_139338362 0.08 ENSMUST00000031521.13
cytochrome P450, family 2, subfamily w, polypeptide 1
chr5_-_100521343 0.08 ENSMUST00000182433.8
Sec31 homolog A (S. cerevisiae)
chr4_+_126156118 0.07 ENSMUST00000030660.9
trafficking protein particle complex 3
chr2_-_79959178 0.07 ENSMUST00000102654.11
ENSMUST00000102655.10
phosphodiesterase 1A, calmodulin-dependent
chr2_+_14179324 0.06 ENSMUST00000077517.9
transmembrane protein 236
chr1_-_139304779 0.06 ENSMUST00000196402.5
ENSMUST00000059825.12
crumbs family member 1, photoreceptor morphogenesis associated
chr14_+_53279810 0.06 ENSMUST00000198439.5
ENSMUST00000103605.3
T cell receptor alpha variable 8D-2
chr18_+_23548192 0.06 ENSMUST00000222515.2
dystrobrevin alpha
chr2_-_166885414 0.05 ENSMUST00000067584.7
zinc finger, NFX1-type containing 1
chr7_+_30487322 0.05 ENSMUST00000189673.7
ENSMUST00000190990.7
ENSMUST00000189962.7
ENSMUST00000187493.7
ENSMUST00000098559.3
keratinocyte differentiation associated protein
chr16_+_90628001 0.04 ENSMUST00000099543.10
eva-1 homolog C (C. elegans)
chr9_+_49014020 0.04 ENSMUST00000070390.12
ENSMUST00000167095.8
transmembrane protease, serine 5 (spinesin)
chr2_+_25179903 0.04 ENSMUST00000028337.7
leucine rich repeat containing 26
chr18_+_23548455 0.04 ENSMUST00000115832.4
dystrobrevin alpha
chr10_-_53252210 0.04 ENSMUST00000095691.7
centrosomal protein 85-like
chr4_+_136011969 0.03 ENSMUST00000144217.8
zinc finger protein 46
chr5_+_124065481 0.03 ENSMUST00000166129.5
predicted gene 43518
chr10_+_52265049 0.03 ENSMUST00000219730.2
nephrocan
chr2_-_76503382 0.02 ENSMUST00000002809.14
FK506 binding protein 7
chr5_-_31296173 0.02 ENSMUST00000043475.7
ENSMUST00000201184.2
urocortin
chr14_-_63275282 0.02 ENSMUST00000111207.8
ENSMUST00000100490.3
defensin beta 30
chr14_+_32555912 0.02 ENSMUST00000104926.3
family with sequence similarity 170, member B
chr3_-_33136153 0.02 ENSMUST00000108225.10
peroxisomal biogenesis factor 5-like
chrX_-_50031587 0.01 ENSMUST00000060650.7
FERM domain containing 7
chr19_+_22425534 0.01 ENSMUST00000235522.2
ENSMUST00000236372.2
ENSMUST00000238066.2
ENSMUST00000235780.2
ENSMUST00000236804.2
transient receptor potential cation channel, subfamily M, member 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 16.6 GO:0034757 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
1.2 7.4 GO:0015889 cobalamin transport(GO:0015889)
0.9 3.5 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.7 3.0 GO:0006507 GPI anchor release(GO:0006507) regulation of high-density lipoprotein particle clearance(GO:0010982)
0.5 1.5 GO:1903334 positive regulation of protein folding(GO:1903334)
0.4 3.2 GO:0061709 reticulophagy(GO:0061709)
0.3 3.7 GO:0006569 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.3 3.9 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.3 4.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 3.2 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.3 2.5 GO:0005513 detection of calcium ion(GO:0005513)
0.3 0.8 GO:0071288 cellular response to mercury ion(GO:0071288)
0.3 2.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 1.0 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.3 1.8 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.2 0.8 GO:0019858 cytosine metabolic process(GO:0019858)
0.2 1.2 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.2 0.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.7 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.2 1.7 GO:0015670 carbon dioxide transport(GO:0015670)
0.2 0.5 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.2 2.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 9.0 GO:0050909 sensory perception of taste(GO:0050909)
0.2 0.5 GO:0038190 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
0.2 0.5 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.9 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.7 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 1.7 GO:0060613 fat pad development(GO:0060613)
0.1 4.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.8 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 1.0 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 1.4 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.1 0.8 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 0.8 GO:0086043 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.1 0.5 GO:0071931 Cajal body organization(GO:0030576) positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.1 0.4 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 1.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.4 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.5 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.5 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 0.2 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.5 GO:0048496 determination of pancreatic left/right asymmetry(GO:0035469) maintenance of organ identity(GO:0048496)
0.1 1.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.1 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.3 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.1 GO:0042414 epinephrine metabolic process(GO:0042414)
0.0 0.3 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 3.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.4 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.2 GO:0072053 renal inner medulla development(GO:0072053)
0.0 1.2 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 1.0 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.6 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.0 1.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0034465 response to carbon monoxide(GO:0034465) eye blink reflex(GO:0060082)
0.0 3.4 GO:0006956 complement activation(GO:0006956)
0.0 0.6 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.8 GO:0051642 centrosome localization(GO:0051642)
0.0 0.8 GO:0009268 response to pH(GO:0009268)
0.0 0.5 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.9 GO:0034706 sodium channel complex(GO:0034706)
0.3 4.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 2.5 GO:0031045 dense core granule(GO:0031045)
0.1 3.2 GO:0005922 connexon complex(GO:0005922)
0.1 0.5 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 3.4 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 1.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0016014 dystrobrevin complex(GO:0016014)
0.1 0.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 3.5 GO:0035371 microtubule plus-end(GO:0035371)
0.1 2.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.5 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 3.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.0 GO:0043196 varicosity(GO:0043196)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 3.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 7.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 25.0 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.7 9.0 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.7 7.4 GO:0031419 cobalamin binding(GO:0031419)
0.4 3.4 GO:0001849 complement component C1q binding(GO:0001849)
0.3 3.0 GO:0004630 phospholipase D activity(GO:0004630)
0.2 4.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 1.6 GO:0070404 NADH binding(GO:0070404)
0.2 1.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.2 3.2 GO:0005243 gap junction channel activity(GO:0005243)
0.2 1.8 GO:0032564 dATP binding(GO:0032564)
0.2 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 2.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.5 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 3.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.5 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 16.6 GO:0005179 hormone activity(GO:0005179)
0.1 1.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 3.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.5 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.8 GO:0045340 mercury ion binding(GO:0045340)
0.1 0.3 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.2 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.4 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 1.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.5 GO:0005113 patched binding(GO:0005113)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 3.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.5 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 1.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 4.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.6 GO:0004177 aminopeptidase activity(GO:0004177)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 2.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.8 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 2.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 4.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 3.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.5 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling