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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Pitx2_Otx2

Z-value: 3.46

Motif logo

Transcription factors associated with Pitx2_Otx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000028023.17 Pitx2
ENSMUSG00000021848.17 Otx2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pitx2mm39_v1_chr3_+_129007599_1290076210.661.2e-05Click!
Otx2mm39_v1_chr14_-_48902555_489025720.334.8e-02Click!

Activity profile of Pitx2_Otx2 motif

Sorted Z-values of Pitx2_Otx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx2_Otx2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_+_110248815 36.30 ENSMUST00000035061.9
neutrophilic granule protein
chr16_+_36004452 35.63 ENSMUST00000114858.2
cystatin domain containing 4
chr5_+_90638580 27.28 ENSMUST00000042755.7
ENSMUST00000200693.2
alpha fetoprotein
chr16_-_36188086 26.46 ENSMUST00000096089.3
cystatin domain containing 5
chr8_+_85628557 22.04 ENSMUST00000067060.10
ENSMUST00000239392.2
Kruppel-like factor 1 (erythroid)
chr10_+_79722081 20.70 ENSMUST00000046091.7
elastase, neutrophil expressed
chr10_+_128736827 19.50 ENSMUST00000219317.2
CD63 antigen
chr6_-_88875646 18.08 ENSMUST00000058011.8
minichromosome maintenance complex component 2
chr3_-_90603013 17.38 ENSMUST00000069960.12
ENSMUST00000117167.2
S100 calcium binding protein A9 (calgranulin B)
chr16_+_36097313 17.33 ENSMUST00000232150.2
stefin A1
chr17_-_35407403 17.33 ENSMUST00000097336.5
leukocyte specific transcript 1
chr17_+_36172210 17.20 ENSMUST00000074259.15
ENSMUST00000174873.2
nurim (nuclear envelope membrane protein)
chr11_-_6470918 15.89 ENSMUST00000003459.4
myosin IG
chr14_-_70867588 15.58 ENSMUST00000228009.2
dematin actin binding protein
chr7_+_16515265 15.57 ENSMUST00000108496.9
solute carrier family 1 (neutral amino acid transporter), member 5
chr10_-_62178453 14.61 ENSMUST00000143179.2
ENSMUST00000130422.8
hexokinase 1
chr15_-_78739717 14.36 ENSMUST00000044584.6
lectin, galactose-binding, soluble 2
chr7_-_45173193 13.26 ENSMUST00000211212.2
protein phosphatase 1, regulatory subunit 15A
chr2_+_91376650 12.94 ENSMUST00000099716.11
ENSMUST00000046769.16
ENSMUST00000111337.3
cytoskeleton associated protein 5
chr3_-_36626101 12.52 ENSMUST00000029270.10
cyclin A2
chr2_-_32278245 12.05 ENSMUST00000192241.2
lipocalin 2
chr11_-_97886997 11.84 ENSMUST00000042971.16
ADP-ribosylation factor-like 5C
chr7_-_45175570 11.76 ENSMUST00000167273.2
ENSMUST00000042105.11
protein phosphatase 1, regulatory subunit 15A
chr2_-_165242307 11.58 ENSMUST00000029213.5
osteoclast stimulatory transmembrane protein
chr7_+_140711181 11.58 ENSMUST00000026568.10
phosphatidylserine synthase 2
chr7_-_143014726 11.53 ENSMUST00000167912.9
ENSMUST00000037287.8
cyclin-dependent kinase inhibitor 1C (P57)
chr14_+_31888061 11.47 ENSMUST00000164341.2
nuclear receptor coactivator 4
chr7_-_143013899 11.45 ENSMUST00000208137.2
ENSMUST00000207910.2
cyclin-dependent kinase inhibitor 1C (P57)
chr16_+_36097505 11.39 ENSMUST00000042097.11
stefin A1
chr11_+_61847589 11.36 ENSMUST00000201671.4
ENSMUST00000202178.4
sperm antigen with calponin homology and coiled-coil domains 1
chr9_-_70328816 11.09 ENSMUST00000034742.8
cyclin B2
chr6_-_115739284 11.04 ENSMUST00000166254.7
ENSMUST00000170625.8
transmembrane protein 40
chr12_+_83572774 11.03 ENSMUST00000223291.2
DDB1 and CUL4 associated factor 4
chr11_-_116472272 10.82 ENSMUST00000082152.5
ubiquitin-conjugating enzyme E2O
chr10_-_128237087 10.78 ENSMUST00000042666.13
solute carrier family 39 (metal ion transporter), member 5
chr11_-_83177548 10.73 ENSMUST00000163961.3
schlafen 14
chr17_-_26163906 10.68 ENSMUST00000085027.4
ENSMUST00000237570.2
NHL repeat containing 4
phosphatidylinositol glycan anchor biosynthesis, class Q
chrX_+_8137881 10.36 ENSMUST00000115590.2
solute carrier family 38, member 5
chrX_-_7844265 10.22 ENSMUST00000125418.2
GATA binding protein 1
chr4_-_117039809 10.17 ENSMUST00000065896.9
kinesin family member 2C
chr11_+_117673107 10.07 ENSMUST00000050874.14
ENSMUST00000106334.9
transmembrane channel-like gene family 8
chr17_-_35304582 9.92 ENSMUST00000038507.7
lymphocyte antigen 6 complex, locus G6F
chr17_+_36172235 9.63 ENSMUST00000172931.2
nurim (nuclear envelope membrane protein)
chr10_+_80128248 9.62 ENSMUST00000068408.14
ENSMUST00000062674.7
ribosomal protein S15
chr9_+_20940669 9.61 ENSMUST00000001040.7
ENSMUST00000215077.2
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr17_+_29712008 9.56 ENSMUST00000234665.2
proviral integration site 1
chr18_-_60635059 9.40 ENSMUST00000042710.8
small integral membrane protein 3
chr17_-_6923299 9.32 ENSMUST00000179554.3
dynein light chain Tctex-type 1F
chr9_+_72345267 9.22 ENSMUST00000183809.8
meiosis-specific nuclear structural protein 1
chr11_+_94901104 9.10 ENSMUST00000124735.2
sterile alpha motif domain containing 14
chr11_-_106889291 9.09 ENSMUST00000124541.8
karyopherin (importin) alpha 2
chr15_+_97682210 9.09 ENSMUST00000117892.2
ENSMUST00000229084.2
solute carrier family 48 (heme transporter), member 1
chr9_-_107863062 8.81 ENSMUST00000048568.6
inka box actin regulator 1
chr7_+_28140450 8.75 ENSMUST00000135686.2
glia maturation factor, gamma
chr17_-_33932346 8.63 ENSMUST00000173392.2
membrane associated ring-CH-type finger 2
chr11_+_61847622 8.61 ENSMUST00000202389.4
sperm antigen with calponin homology and coiled-coil domains 1
chr10_+_128744689 8.50 ENSMUST00000105229.9
CD63 antigen
chr6_-_125168637 8.49 ENSMUST00000043848.11
non-SMC condensin I complex, subunit D2
chr1_-_153425791 8.19 ENSMUST00000041874.9
N-acetylneuraminate pyruvate lyase
chr11_-_55075855 8.13 ENSMUST00000039305.6
solute carrier family 36 (proton/amino acid symporter), member 2
chr17_+_6697511 8.08 ENSMUST00000179569.3
dynein light chain Tctex-type 1B
chr16_+_38182569 7.96 ENSMUST00000023494.13
ENSMUST00000114739.2
popeye domain containing 2
chr7_-_19410749 7.91 ENSMUST00000003074.16
apolipoprotein C-II
chr4_-_117013396 7.82 ENSMUST00000102696.5
ribosomal protein S8
chr18_+_34869412 7.73 ENSMUST00000105038.3
predicted gene 3550
chr16_-_36154692 7.67 ENSMUST00000114850.3
cystatin domain containing 6
chrX_+_162923474 7.65 ENSMUST00000073973.11
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr13_-_113237505 7.64 ENSMUST00000224282.2
ENSMUST00000023897.7
granzyme A
chr7_+_28140352 7.47 ENSMUST00000078845.13
glia maturation factor, gamma
chrX_-_9335525 7.45 ENSMUST00000015484.10
cytochrome b-245, beta polypeptide
chr15_-_82128888 7.43 ENSMUST00000089155.6
ENSMUST00000089157.11
centromere protein M
chr14_-_47655621 7.41 ENSMUST00000180299.8
DLG associated protein 5
chr5_-_100720063 7.32 ENSMUST00000031264.12
placenta-specific 8
chr8_-_124709859 7.21 ENSMUST00000075578.7
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr6_+_72521374 7.19 ENSMUST00000071044.13
ENSMUST00000114072.8
capping protein (actin filament), gelsolin-like
chr17_-_25946370 7.11 ENSMUST00000170070.3
ENSMUST00000048054.14
CTF18, chromosome transmission fidelity factor 18
chr8_-_122634418 7.07 ENSMUST00000045557.10
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr16_+_36030773 7.04 ENSMUST00000089628.4
cystatin A family member 3
chr7_-_24997291 7.00 ENSMUST00000148150.8
ENSMUST00000155118.2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr11_+_32155415 6.97 ENSMUST00000039601.10
ENSMUST00000149043.3
small nuclear ribonucleoprotein 25 (U11/U12)
chr10_+_20223516 6.94 ENSMUST00000169712.3
ENSMUST00000217608.2
mitochondrial fission regulator 2
chr3_-_152045986 6.92 ENSMUST00000199397.2
ENSMUST00000199334.5
ENSMUST00000068243.11
ENSMUST00000073089.13
mitoguardin 1
chr7_-_128019874 6.84 ENSMUST00000145739.3
ENSMUST00000033133.12
regulator of G-protein signalling 10
chr8_+_23629080 6.82 ENSMUST00000033947.15
ankyrin 1, erythroid
chr6_+_86605146 6.74 ENSMUST00000043400.9
aspartic peptidase, retroviral-like 1
chr7_-_117715394 6.59 ENSMUST00000131374.8
ribosomal protein S15A
chr16_-_8610165 6.57 ENSMUST00000160405.8
ubiquitin specific peptidase 7
chr11_+_114559350 6.55 ENSMUST00000106602.10
ENSMUST00000077915.10
ENSMUST00000106599.8
ENSMUST00000082092.5
ribosomal protein L38
chr6_+_34331054 6.52 ENSMUST00000038406.7
aldo-keto reductase family 1, member B8
chr5_+_110478558 6.48 ENSMUST00000112481.2
polymerase (DNA directed), epsilon
chr17_+_56259617 6.47 ENSMUST00000003274.8
Epstein-Barr virus induced gene 3
chr9_+_72345801 6.40 ENSMUST00000184604.8
ENSMUST00000034746.10
meiosis-specific nuclear structural protein 1
chr4_-_116851550 6.37 ENSMUST00000130273.8
uroporphyrinogen decarboxylase
chr7_-_133304244 6.36 ENSMUST00000209636.2
ENSMUST00000153698.3
uroporphyrinogen III synthase
chrX_-_7956682 6.30 ENSMUST00000033505.7
Wiskott-Aldrich syndrome
chr17_+_29333116 6.28 ENSMUST00000233717.2
ENSMUST00000141239.2
RAB44, member RAS oncogene family
chr5_-_129856237 6.28 ENSMUST00000118268.9
phosphoserine phosphatase
chr11_-_102815910 6.14 ENSMUST00000021311.10
kinesin family member 18B
chr11_-_115918784 6.10 ENSMUST00000106454.8
H3.3 histone B
chr10_+_7543260 6.09 ENSMUST00000040135.9
nucleoporin 43
chr5_-_129856267 6.03 ENSMUST00000201394.4
phosphoserine phosphatase
chr4_-_116851571 5.99 ENSMUST00000030446.15
uroporphyrinogen decarboxylase
chr9_-_114811807 5.81 ENSMUST00000053150.8
ribosomal protein S27, retrogene
chr15_-_99268311 5.79 ENSMUST00000081224.14
ENSMUST00000120633.2
ENSMUST00000088233.13
formin-like 3
chr9_+_62754252 5.73 ENSMUST00000124984.2
ceroid-lipofuscinosis, neuronal 6
chr7_-_100164007 5.70 ENSMUST00000207405.2
DnaJ heat shock protein family (Hsp40) member B13
chr5_+_108048367 5.69 ENSMUST00000082223.13
ribosomal protein L5
chr11_-_117673008 5.64 ENSMUST00000152304.3
transmembrane channel-like gene family 6
chr7_+_19024994 5.60 ENSMUST00000108468.5
reticulon 2 (Z-band associated protein)
chr4_-_149221998 5.59 ENSMUST00000176124.8
ENSMUST00000177408.2
ENSMUST00000105695.2
centromere protein S
chr19_-_6996791 5.54 ENSMUST00000040772.9
fermitin family member 3
chr15_-_76554065 5.51 ENSMUST00000037824.6
forkhead box H1
chr17_+_48539782 5.50 ENSMUST00000113251.10
ENSMUST00000048782.7
triggering receptor expressed on myeloid cells 1
chr19_+_4204605 5.49 ENSMUST00000061086.9
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr7_-_24997393 5.41 ENSMUST00000005583.12
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr9_-_58648826 5.38 ENSMUST00000098674.6
REC114 meiotic recombination protein
chr19_-_17316906 5.38 ENSMUST00000169897.2
glucosaminyl (N-acetyl) transferase 1, core 2
chr9_+_103182352 5.34 ENSMUST00000035164.10
topoisomerase (DNA) II binding protein 1
chr7_-_110581652 5.33 ENSMUST00000005751.13
inositol 1,4,5-triphosphate receptor associated 1
chr4_-_149222057 5.30 ENSMUST00000030813.10
centromere protein S
chr3_-_105839980 5.29 ENSMUST00000098758.5
RIKEN cDNA I830077J02 gene
chr19_+_8861096 5.28 ENSMUST00000187504.7
LBH domain containing 1
chr6_+_35154319 5.27 ENSMUST00000201374.4
ENSMUST00000043815.16
nucleoporin 205
chr3_+_129672205 5.19 ENSMUST00000029629.15
phospholipase A2, group XIIA
chr8_+_23629046 5.17 ENSMUST00000121075.8
ankyrin 1, erythroid
chr11_+_68936457 5.11 ENSMUST00000108666.8
ENSMUST00000021277.6
aurora kinase B
chrX_-_161747552 5.08 ENSMUST00000038769.3
S100 calcium binding protein G
chr14_+_71011744 5.06 ENSMUST00000022698.8
docking protein 2
chr11_+_101333115 5.03 ENSMUST00000077856.13
ribosomal protein L27
chr19_+_8870362 5.02 ENSMUST00000096249.7
integrator complex subunit 5
chr4_+_154096188 5.00 ENSMUST00000169622.8
ENSMUST00000030894.15
leucine rich repeat containing 47
chr17_+_6869070 4.97 ENSMUST00000092966.5
dynein light chain Tctex-type 1C
chr11_-_101979297 4.93 ENSMUST00000017458.11
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr19_+_37364791 4.90 ENSMUST00000012587.4
kinesin family member 11
chr15_-_89310060 4.87 ENSMUST00000109313.9
carnitine palmitoyltransferase 1b, muscle
chr14_-_54949596 4.86 ENSMUST00000064290.8
CCAAT/enhancer binding protein (C/EBP), epsilon
chr7_+_141027763 4.83 ENSMUST00000106003.2
ribosomal protein, large P2
chr8_+_118225008 4.81 ENSMUST00000081232.9
phospholipase C, gamma 2
chr14_+_66043515 4.81 ENSMUST00000139644.2
PDZ binding kinase
chr6_-_131270136 4.79 ENSMUST00000032307.12
mago homolog B, exon junction complex core component
chr7_-_30144933 4.74 ENSMUST00000006828.9
amyloid beta (A4) precursor-like protein 1
chr15_+_59186876 4.65 ENSMUST00000022977.14
ENSMUST00000100640.5
squalene epoxidase
chr15_-_83479312 4.62 ENSMUST00000016901.5
tubulin tyrosine ligase-like family, member 12
chr5_-_139722046 4.61 ENSMUST00000044642.14
MICAL-like 2
chr10_+_62782786 4.57 ENSMUST00000131422.8
DNA replication helicase/nuclease 2
chr2_-_126342551 4.56 ENSMUST00000129187.2
ATPase, class I, type 8B, member 4
chr4_-_156340276 4.54 ENSMUST00000220228.2
ENSMUST00000218788.2
ENSMUST00000179919.3
sterile alpha motif domain containing 11
chr1_-_128520002 4.51 ENSMUST00000052172.7
ENSMUST00000142893.2
chemokine (C-X-C motif) receptor 4
chr13_-_97235745 4.48 ENSMUST00000071118.7
predicted gene 6169
chr7_-_30119227 4.48 ENSMUST00000208740.2
ENSMUST00000075062.5
hematopoietic cell signal transducer
chr15_+_80832685 4.45 ENSMUST00000023043.10
ENSMUST00000164806.6
ENSMUST00000207170.2
ENSMUST00000168756.8
adenylosuccinate lyase
chr2_+_32477069 4.43 ENSMUST00000102818.11
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr8_-_11685726 4.40 ENSMUST00000033905.13
ENSMUST00000169782.3
ankyrin repeat domain 10
chr2_-_5900130 4.40 ENSMUST00000026926.5
ENSMUST00000193792.6
ENSMUST00000102981.10
Sec61, alpha subunit 2 (S. cerevisiae)
chr10_+_128073900 4.38 ENSMUST00000105245.3
timeless circadian clock 1
chr5_+_115697526 4.32 ENSMUST00000086519.12
ENSMUST00000156359.2
ENSMUST00000152976.2
ribosomal protein, large, P0
chr11_-_5102218 4.29 ENSMUST00000163299.8
ENSMUST00000062821.13
EMI domain containing 1
chr7_+_127503251 4.28 ENSMUST00000071056.14
branched chain ketoacid dehydrogenase kinase
chr14_+_43951187 4.28 ENSMUST00000094051.6
predicted gene 7324
chr1_-_172722589 4.26 ENSMUST00000027824.7
serum amyloid P-component
chr12_-_69205882 4.22 ENSMUST00000037023.9
ribosomal protein S29
chr8_+_61343444 4.21 ENSMUST00000146863.2
ENSMUST00000037190.15
histone PARylation factor 1
chr10_-_79875479 4.17 ENSMUST00000004786.10
polymerase (RNA) II (DNA directed) polypeptide E
chr7_-_47178610 4.14 ENSMUST00000172559.2
MAS-related GPR, member A2B
chr11_-_84719779 4.12 ENSMUST00000047560.8
dehydrogenase/reductase (SDR family) member 11
chr12_-_75678092 4.12 ENSMUST00000238938.2
ribosomal protein, large P2, pseudogene 1
chr2_+_174257597 4.11 ENSMUST00000109075.8
ENSMUST00000016397.7
negative elongation factor complex member C/D, Th1l
chr2_-_34645241 4.11 ENSMUST00000102800.9
GTPase activating protein and VPS9 domains 1
chr4_+_156194427 4.09 ENSMUST00000072554.13
ENSMUST00000169550.8
ENSMUST00000105576.2
RIKEN cDNA 9430015G10 gene
chr14_-_54655079 4.07 ENSMUST00000226753.2
ENSMUST00000197440.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr5_+_139239247 4.07 ENSMUST00000138508.8
ENSMUST00000110878.2
golgi to ER traffic protein 4
chr10_+_79650496 4.01 ENSMUST00000218857.2
ENSMUST00000220365.2
paralemmin
chr9_+_20799471 3.99 ENSMUST00000004203.6
peter pan homolog
chr7_+_101530524 3.98 ENSMUST00000106978.8
anaphase promoting complex C subunit 15
chr14_-_99231754 3.97 ENSMUST00000081987.5
ribosomal protein L36A, pseudogene 1
chr15_-_36598263 3.97 ENSMUST00000155116.2
poly(A) binding protein, cytoplasmic 1
chr18_+_35932894 3.95 ENSMUST00000236484.2
ENSMUST00000236550.2
ENSMUST00000235919.2
ubiquitin-conjugating enzyme E2D 2A
predicted gene, 50371
chr11_-_120238917 3.95 ENSMUST00000106215.11
actin, gamma, cytoplasmic 1
chr15_-_82128538 3.93 ENSMUST00000229747.2
ENSMUST00000230408.2
centromere protein M
chr14_-_70414236 3.92 ENSMUST00000153735.8
PDZ and LIM domain 2
chr9_+_119939414 3.92 ENSMUST00000035106.12
solute carrier family 25, member 38
chr1_-_23948764 3.91 ENSMUST00000129254.8
small ArfGAP 1
chr4_+_130640436 3.89 ENSMUST00000151698.8
lysosomal-associated protein transmembrane 5
chr12_-_79027531 3.88 ENSMUST00000174072.8
transmembrane protein 229B
chr11_-_78074377 3.86 ENSMUST00000102483.5
ribosomal protein L23A
chr10_+_79832313 3.83 ENSMUST00000132517.8
ATP-binding cassette, sub-family A (ABC1), member 7
chr16_-_4536943 3.82 ENSMUST00000120056.8
ENSMUST00000074970.8
NmrA-like family domain containing 1
chr7_+_16726633 3.79 ENSMUST00000094805.5
coiled-coil domain containing 8
chr1_-_167112784 3.77 ENSMUST00000053686.9
uridine-cytidine kinase 2
chr16_+_55786638 3.77 ENSMUST00000023269.5
ribosomal protein L24
chr18_-_74340842 3.74 ENSMUST00000040188.16
spindle and kinetochore associated complex subunit 1
chr16_+_17437205 3.74 ENSMUST00000006053.13
ENSMUST00000231311.2
ENSMUST00000163476.10
ENSMUST00000231257.2
ENSMUST00000165363.10
ENSMUST00000232043.2
ENSMUST00000090159.13
ENSMUST00000232442.2
sphingomyelin phosphodiesterase 4
chr6_+_42326760 3.73 ENSMUST00000203652.3
ENSMUST00000070635.13
zyxin
chr10_+_127159568 3.71 ENSMUST00000219026.2
Rho GTPase activating protein 9
chr7_+_65710086 3.68 ENSMUST00000153609.8
small nuclear ribonucleoprotein polypeptide A'
chr13_-_38842967 3.67 ENSMUST00000001757.9
eukaryotic translation elongation factor 1 epsilon 1
chr3_-_54823287 3.67 ENSMUST00000070342.4
serine rich and transmembrane domain containing 1
chr7_-_6699422 3.66 ENSMUST00000122432.4
ENSMUST00000002336.16
zinc finger, imprinted 1
chr16_-_4536992 3.65 ENSMUST00000115851.10
NmrA-like family domain containing 1
chr5_+_114924106 3.61 ENSMUST00000137519.2
ankyrin repeat domain 13a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.1 36.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
8.3 25.0 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
6.9 20.7 GO:0070947 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780) neutrophil mediated killing of fungus(GO:0070947)
5.8 17.4 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
5.4 16.2 GO:0071846 actin filament debranching(GO:0071846)
5.2 15.6 GO:0015825 L-serine transport(GO:0015825)
4.7 28.0 GO:2000680 regulation of rubidium ion transport(GO:2000680)
4.0 12.0 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
3.9 23.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
3.7 18.7 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
3.4 13.8 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
3.4 10.2 GO:0030221 basophil differentiation(GO:0030221)
3.0 12.0 GO:0036233 glycine import(GO:0036233)
2.9 11.6 GO:0034241 positive regulation of macrophage fusion(GO:0034241) positive regulation of osteoclast proliferation(GO:0090290)
2.6 15.6 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
2.4 19.4 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
2.2 6.5 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
2.2 6.5 GO:0045004 DNA replication proofreading(GO:0045004)
2.2 10.8 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
2.1 6.3 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
2.1 22.9 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
2.0 7.9 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
1.9 7.7 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
1.9 5.7 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
1.9 7.6 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
1.7 5.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
1.7 11.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
1.6 4.9 GO:0032976 release of matrix enzymes from mitochondria(GO:0032976) B cell receptor apoptotic signaling pathway(GO:1990117)
1.6 4.8 GO:0006597 spermine biosynthetic process(GO:0006597)
1.6 27.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
1.6 8.0 GO:0060931 sinoatrial node cell development(GO:0060931)
1.6 4.7 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
1.5 18.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.5 4.4 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
1.4 5.7 GO:1904158 axonemal central apparatus assembly(GO:1904158)
1.4 4.3 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.4 4.2 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
1.3 10.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.3 4.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
1.3 6.6 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.3 23.5 GO:0043249 erythrocyte maturation(GO:0043249)
1.3 9.1 GO:0015886 heme transport(GO:0015886)
1.3 3.8 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
1.3 3.8 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) CMP metabolic process(GO:0046035)
1.3 3.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
1.2 6.1 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
1.2 10.7 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.2 8.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
1.1 3.4 GO:0002880 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
1.1 4.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
1.1 5.6 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.1 5.5 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
1.1 3.3 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
1.1 6.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
1.1 4.3 GO:0017126 nucleologenesis(GO:0017126)
1.1 9.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.0 2.0 GO:0002358 B cell homeostatic proliferation(GO:0002358)
1.0 4.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
1.0 2.9 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
1.0 2.9 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
1.0 7.6 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.9 2.8 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.9 9.4 GO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.9 2.7 GO:0033189 response to vitamin A(GO:0033189)
0.9 0.9 GO:0071029 polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.9 4.4 GO:0015966 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.9 4.4 GO:1901355 response to rapamycin(GO:1901355)
0.9 6.9 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.9 6.0 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.9 3.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.9 3.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.9 2.6 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.8 8.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.8 3.4 GO:2001188 negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.8 2.5 GO:1904456 negative regulation of neuronal action potential(GO:1904456)
0.8 5.8 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.8 24.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.8 12.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.8 2.5 GO:0046101 GMP catabolic process(GO:0046038) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.8 16.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.8 4.7 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.8 6.3 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.8 3.9 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.8 10.7 GO:0015816 glycine transport(GO:0015816)
0.8 2.3 GO:1990764 gastrin-induced gastric acid secretion(GO:0001698) positive regulation of actin filament-based movement(GO:1903116) regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) negative regulation of forebrain neuron differentiation(GO:2000978)
0.7 5.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.7 5.0 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.7 2.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.7 5.6 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.7 2.8 GO:0035546 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.7 2.1 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.7 13.5 GO:0051382 kinetochore assembly(GO:0051382)
0.7 4.0 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.6 13.2 GO:0070986 left/right axis specification(GO:0070986)
0.6 1.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.6 3.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.6 5.5 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.6 2.5 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.6 3.0 GO:0009597 detection of virus(GO:0009597)
0.6 2.4 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.6 5.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.6 3.0 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.6 1.7 GO:0009233 menaquinone metabolic process(GO:0009233)
0.6 3.4 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.6 2.2 GO:0015744 succinate transport(GO:0015744)
0.6 12.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.6 2.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.6 1.7 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.6 1.7 GO:0034769 basement membrane disassembly(GO:0034769)
0.6 1.7 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.5 4.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.5 4.9 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.5 15.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.5 1.6 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.5 5.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.5 3.7 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.5 6.8 GO:1904667 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.5 2.1 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.5 5.7 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.5 0.5 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.5 4.1 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.5 7.1 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.5 2.0 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.5 1.4 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904)
0.5 2.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.5 2.4 GO:0070543 response to linoleic acid(GO:0070543)
0.5 2.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.5 4.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.4 1.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.4 10.8 GO:0016180 snRNA processing(GO:0016180)
0.4 2.6 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.4 1.7 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.4 3.4 GO:0048539 bone marrow development(GO:0048539)
0.4 2.0 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.4 1.6 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.4 8.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.4 1.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.4 5.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.4 1.9 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.4 17.7 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.4 3.0 GO:0070294 renal sodium ion absorption(GO:0070294)
0.4 1.1 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.4 7.7 GO:0006999 nuclear pore organization(GO:0006999)
0.4 3.3 GO:0006004 fucose metabolic process(GO:0006004)
0.4 0.7 GO:0009644 response to high light intensity(GO:0009644)
0.4 1.8 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.4 1.8 GO:1990743 protein sialylation(GO:1990743)
0.4 0.7 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.4 2.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 15.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 2.8 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.3 3.8 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.3 0.3 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.3 1.4 GO:0015811 L-cystine transport(GO:0015811)
0.3 1.7 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.3 1.4 GO:1902896 terminal web assembly(GO:1902896)
0.3 3.4 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.3 11.2 GO:0048821 erythrocyte development(GO:0048821)
0.3 13.4 GO:0055069 zinc ion homeostasis(GO:0055069)
0.3 1.0 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.3 1.0 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685) negative regulation of interleukin-18 production(GO:0032701)
0.3 1.3 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.3 3.5 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.3 3.2 GO:0030916 otic vesicle formation(GO:0030916)
0.3 3.2 GO:0035878 nail development(GO:0035878)
0.3 1.3 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.3 5.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.3 1.5 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.3 4.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3 1.2 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.3 1.5 GO:1903936 response to diamide(GO:0072737) cellular response to diamide(GO:0072738) cellular response to sodium arsenite(GO:1903936)
0.3 3.0 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 4.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.3 1.2 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.3 0.9 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.3 0.9 GO:0002543 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.3 1.4 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.3 0.9 GO:1904266 regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.3 7.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.3 3.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.3 2.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.3 1.7 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.3 0.3 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.3 13.0 GO:0016572 histone phosphorylation(GO:0016572)
0.3 5.4 GO:0060352 cell adhesion molecule production(GO:0060352)
0.3 2.4 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.3 0.8 GO:2000642 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.3 2.1 GO:0006527 arginine catabolic process(GO:0006527)
0.3 0.5 GO:0036337 Fas signaling pathway(GO:0036337)
0.3 2.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.3 2.3 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.3 2.3 GO:0009249 protein lipoylation(GO:0009249)
0.2 2.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 1.7 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 1.7 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.2 1.7 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.2 1.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 2.3 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.2 8.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.2 8.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.2 1.8 GO:0033277 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) abortive mitotic cell cycle(GO:0033277)
0.2 0.9 GO:0048478 replication fork protection(GO:0048478)
0.2 2.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 0.7 GO:0002355 detection of tumor cell(GO:0002355)
0.2 5.2 GO:0019081 viral translation(GO:0019081)
0.2 0.9 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.2 1.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.2 1.5 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 1.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 10.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 0.8 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.2 5.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 2.5 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.2 9.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.2 2.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 1.2 GO:0034227 tRNA thio-modification(GO:0034227)
0.2 2.8 GO:0071294 cellular response to zinc ion(GO:0071294)
0.2 4.9 GO:0042572 retinol metabolic process(GO:0042572)
0.2 2.4 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.2 2.9 GO:0032099 negative regulation of appetite(GO:0032099)
0.2 1.4 GO:0035989 tendon development(GO:0035989)
0.2 1.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 2.1 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2 1.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 2.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.2 4.2 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 4.6 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2 7.9 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.2 0.4 GO:0090135 actin filament branching(GO:0090135)
0.2 7.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 1.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.2 0.9 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.2 0.4 GO:0006649 phospholipid transfer to membrane(GO:0006649)
0.2 1.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 0.5 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 0.9 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 10.9 GO:0043029 T cell homeostasis(GO:0043029)
0.2 2.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.2 1.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 0.2 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.2 1.5 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 1.0 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 1.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 3.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.2 0.5 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2 3.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 2.5 GO:0046599 regulation of centriole replication(GO:0046599)
0.2 3.5 GO:0035855 megakaryocyte development(GO:0035855)
0.2 0.5 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.2 0.9 GO:0070586 cell-cell adhesion involved in gastrulation(GO:0070586)
0.2 2.6 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.2 3.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.2 0.8 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.2 0.5 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 9.5 GO:0016925 protein sumoylation(GO:0016925)
0.2 1.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 24.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 1.9 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 2.7 GO:0000338 protein deneddylation(GO:0000338)
0.1 1.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 2.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 3.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.7 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 3.9 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 1.6 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 1.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.7 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.1 0.6 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 3.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 1.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 6.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 5.0 GO:0032456 endocytic recycling(GO:0032456)
0.1 2.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 1.0 GO:0006449 regulation of translational termination(GO:0006449)
0.1 8.0 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.1 0.4 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 5.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 3.6 GO:0030225 macrophage differentiation(GO:0030225)
0.1 0.8 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.1 0.3 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.1 2.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.3 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 2.7 GO:0030220 platelet formation(GO:0030220)
0.1 1.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 3.7 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 0.3 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 2.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 5.4 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.6 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 1.4 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.1 2.5 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 4.7 GO:0009409 response to cold(GO:0009409)
0.1 2.0 GO:0031297 replication fork processing(GO:0031297) DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.1 1.8 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.4 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.9 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 1.7 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.4 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.1 0.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 1.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1 1.2 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.1 3.9 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.1 0.9 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.1 1.1 GO:0016926 protein desumoylation(GO:0016926)
0.1 12.9 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 1.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 1.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 1.2 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.4 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 2.7 GO:0030488 tRNA methylation(GO:0030488)
0.1 17.5 GO:0008360 regulation of cell shape(GO:0008360)
0.1 0.3 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.1 3.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 4.0 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.3 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 0.3 GO:0035565 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.1 0.8 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.4 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.6 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.3 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.6 GO:0061370 estrogen biosynthetic process(GO:0006703) testosterone biosynthetic process(GO:0061370)
0.1 1.7 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 0.9 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.2 GO:0021764 amygdala development(GO:0021764)
0.1 0.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.1 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 2.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 1.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 3.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.2 GO:1900738 psychomotor behavior(GO:0036343) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.5 GO:0090042 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.1 0.7 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 0.2 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1 0.3 GO:0098885 modification of postsynaptic actin cytoskeleton(GO:0098885)
0.1 0.4 GO:0044857 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 1.3 GO:0006400 tRNA modification(GO:0006400)
0.0 0.9 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 2.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.0 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.3 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 1.3 GO:0006706 steroid catabolic process(GO:0006706)
0.0 1.2 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 3.3 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 1.1 GO:0043276 anoikis(GO:0043276)
0.0 2.6 GO:0007088 regulation of mitotic nuclear division(GO:0007088)
0.0 0.9 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 2.5 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 1.6 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.6 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 1.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.7 GO:0002076 osteoblast development(GO:0002076) negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 1.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0002396 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.7 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.5 GO:0007398 ectoderm development(GO:0007398)
0.0 0.1 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.1 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 1.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.6 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0070829 chromatin maintenance(GO:0070827) heterochromatin maintenance(GO:0070829)
0.0 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 0.4 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.3 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 1.8 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 1.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.2 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.0 0.8 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 1.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.9 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.4 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.6 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 1.0 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.6 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.5 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.4 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.2 GO:0051642 centrosome localization(GO:0051642)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 28.0 GO:0031904 endosome lumen(GO:0031904)
2.7 10.9 GO:0071821 FANCM-MHF complex(GO:0071821)
2.2 15.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
2.2 6.6 GO:0070992 translation initiation complex(GO:0070992)
1.7 8.7 GO:0031510 SUMO activating enzyme complex(GO:0031510)
1.7 8.5 GO:0000799 nuclear condensin complex(GO:0000799)
1.7 25.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
1.6 18.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.6 4.9 GO:0097144 BAX complex(GO:0097144)
1.6 4.7 GO:1990879 CST complex(GO:1990879)
1.5 4.6 GO:0005760 gamma DNA polymerase complex(GO:0005760)
1.5 5.9 GO:0032021 NELF complex(GO:0032021)
1.4 5.6 GO:0014802 terminal cisterna(GO:0014802)
1.3 6.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.3 29.8 GO:0005652 nuclear lamina(GO:0005652)
1.2 8.3 GO:0044611 nuclear pore inner ring(GO:0044611)
1.1 3.4 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
1.1 18.0 GO:0044754 autolysosome(GO:0044754)
1.1 5.5 GO:0032444 activin responsive factor complex(GO:0032444)
1.1 10.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.0 12.5 GO:0001940 male pronucleus(GO:0001940)
1.0 5.8 GO:0032133 chromosome passenger complex(GO:0032133)
1.0 2.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.8 51.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.8 3.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.8 2.3 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.7 7.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.7 4.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.7 14.0 GO:0005682 U5 snRNP(GO:0005682)
0.7 5.5 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.7 4.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.7 10.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.6 3.9 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.6 3.8 GO:1990393 3M complex(GO:1990393)
0.6 14.4 GO:0005686 U2 snRNP(GO:0005686)
0.6 10.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.6 44.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.6 2.3 GO:1990769 proximal neuron projection(GO:1990769)
0.6 6.1 GO:0000235 astral microtubule(GO:0000235)
0.6 18.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.6 1.7 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.5 3.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.5 9.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.5 17.6 GO:0001891 phagocytic cup(GO:0001891)
0.5 7.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.5 11.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.5 7.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.5 2.0 GO:0035101 FACT complex(GO:0035101)
0.5 6.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.5 9.6 GO:0032039 integrator complex(GO:0032039)
0.5 1.5 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.5 1.0 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.5 1.9 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.5 18.8 GO:0035371 microtubule plus-end(GO:0035371)
0.5 1.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.5 2.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.5 3.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.5 2.8 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.5 1.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.5 4.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.4 6.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.4 10.0 GO:0097526 spliceosomal tri-snRNP complex(GO:0097526)
0.4 2.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.4 7.0 GO:0090543 Flemming body(GO:0090543)
0.4 2.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467) nuclear SCF ubiquitin ligase complex(GO:0043224)
0.4 1.2 GO:0034455 t-UTP complex(GO:0034455)
0.4 2.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.4 11.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.4 5.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.4 3.4 GO:0070545 PeBoW complex(GO:0070545)
0.4 1.1 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.4 3.7 GO:0031415 NatA complex(GO:0031415)
0.4 2.6 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.4 1.4 GO:0060171 stereocilium membrane(GO:0060171)
0.4 6.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.4 15.4 GO:0097228 sperm principal piece(GO:0097228)
0.4 4.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.4 2.5 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.3 1.7 GO:0001939 female pronucleus(GO:0001939)
0.3 2.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.3 2.6 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.3 0.3 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.3 2.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.3 4.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 3.7 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3 4.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 1.5 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.3 1.8 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.3 7.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.3 1.8 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3 11.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 2.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3 1.7 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.3 1.4 GO:1990745 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.3 1.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.3 3.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 5.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3 1.3 GO:0071797 LUBAC complex(GO:0071797)
0.3 0.8 GO:0000814 ESCRT II complex(GO:0000814)
0.3 1.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2 3.0 GO:0000974 Prp19 complex(GO:0000974)
0.2 2.2 GO:0000439 core TFIIH complex(GO:0000439)
0.2 4.7 GO:0030914 STAGA complex(GO:0030914)
0.2 1.9 GO:0042575 DNA polymerase complex(GO:0042575)
0.2 2.8 GO:0032009 early phagosome(GO:0032009)
0.2 8.1 GO:0001741 XY body(GO:0001741)
0.2 1.9 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 6.1 GO:0002102 podosome(GO:0002102)
0.2 3.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 3.0 GO:0031209 SCAR complex(GO:0031209)
0.2 3.7 GO:0071564 npBAF complex(GO:0071564)
0.2 14.5 GO:0005643 nuclear pore(GO:0005643)
0.2 27.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 2.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 10.1 GO:0001772 immunological synapse(GO:0001772)
0.2 0.6 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.2 3.5 GO:0033202 DNA helicase complex(GO:0033202)
0.2 0.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 1.9 GO:0042629 mast cell granule(GO:0042629)
0.2 5.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 24.2 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 0.5 GO:0000791 euchromatin(GO:0000791)
0.2 1.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 15.7 GO:0036126 sperm flagellum(GO:0036126)
0.2 3.3 GO:0035253 ciliary rootlet(GO:0035253)
0.2 1.8 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 0.8 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 3.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.9 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.6 GO:0042788 polysomal ribosome(GO:0042788)
0.1 4.6 GO:0005876 spindle microtubule(GO:0005876)
0.1 3.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 13.8 GO:0000776 kinetochore(GO:0000776)
0.1 1.8 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 4.3 GO:0043596 nuclear replication fork(GO:0043596)
0.1 1.7 GO:0090544 BAF-type complex(GO:0090544)
0.1 1.2 GO:0042382 paraspeckles(GO:0042382)
0.1 1.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.2 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.2 GO:0045179 apical cortex(GO:0045179)
0.1 2.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.8 GO:0070847 core mediator complex(GO:0070847)
0.1 0.9 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 0.8 GO:0030891 VCB complex(GO:0030891)
0.1 1.0 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 4.0 GO:0043034 costamere(GO:0043034)
0.1 0.7 GO:0071914 prominosome(GO:0071914)
0.1 0.9 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 3.6 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.4 GO:0032432 actin filament bundle(GO:0032432)
0.1 0.3 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 1.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.8 GO:1990909 Wnt signalosome(GO:1990909)
0.1 3.3 GO:0030684 preribosome(GO:0030684)
0.1 0.9 GO:0016342 catenin complex(GO:0016342)
0.1 0.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 27.1 GO:0000790 nuclear chromatin(GO:0000790)
0.1 2.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.9 GO:0032982 myosin filament(GO:0032982)
0.1 1.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 4.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 4.5 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 1.6 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 4.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 4.2 GO:0014704 intercalated disc(GO:0014704)
0.1 5.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 2.8 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.9 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 2.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 11.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.3 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.0 3.3 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 2.1 GO:0000502 proteasome complex(GO:0000502)
0.0 2.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.5 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 13.6 GO:0005911 cell-cell junction(GO:0005911)
0.0 2.8 GO:0016605 PML body(GO:0016605)
0.0 5.2 GO:0042383 sarcolemma(GO:0042383)
0.0 1.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0034719 SMN complex(GO:0032797) SMN-Sm protein complex(GO:0034719)
0.0 2.7 GO:0005819 spindle(GO:0005819)
0.0 5.6 GO:0043679 axon terminus(GO:0043679)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 20.4 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 29.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 10.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.6 GO:0019814 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.0 6.8 GO:0016604 nuclear body(GO:0016604)
0.0 0.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.6 GO:0030175 filopodium(GO:0030175)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 27.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
2.9 8.7 GO:0019948 SUMO activating enzyme activity(GO:0019948)
2.8 2.8 GO:0045142 triplex DNA binding(GO:0045142)
2.7 8.1 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
2.2 17.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
2.1 12.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
2.0 8.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.9 7.7 GO:0032093 SAM domain binding(GO:0032093)
1.8 14.4 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.8 12.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
1.6 14.6 GO:0016936 galactoside binding(GO:0016936)
1.5 4.6 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
1.5 9.1 GO:0015232 heme transporter activity(GO:0015232)
1.4 12.5 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.3 4.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.3 6.5 GO:0004074 biliverdin reductase activity(GO:0004074)
1.3 3.8 GO:0090556 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
1.3 23.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
1.3 7.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
1.2 13.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
1.2 7.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
1.2 15.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
1.2 16.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.2 4.7 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
1.2 5.9 GO:0030620 U2 snRNA binding(GO:0030620)
1.1 11.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.1 3.4 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
1.1 3.3 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
1.1 6.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.0 3.0 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
1.0 18.1 GO:0003688 DNA replication origin binding(GO:0003688)
1.0 23.6 GO:0051010 microtubule plus-end binding(GO:0051010)
1.0 10.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.0 3.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.9 4.6 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.9 2.8 GO:0004948 calcitonin receptor activity(GO:0004948)
0.9 10.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.9 11.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.9 6.0 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.8 3.3 GO:0072354 histone kinase activity (H3-T3 specific)(GO:0072354)
0.8 4.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.8 2.4 GO:0030622 U4atac snRNA binding(GO:0030622)
0.8 10.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.7 2.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.7 2.9 GO:1990932 5.8S rRNA binding(GO:1990932)
0.7 2.8 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.7 2.0 GO:0036004 GAF domain binding(GO:0036004)
0.6 6.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.6 4.5 GO:0032027 myosin light chain binding(GO:0032027)
0.6 5.1 GO:0005499 vitamin D binding(GO:0005499)
0.6 0.6 GO:0070401 NADP+ binding(GO:0070401)
0.6 7.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.6 7.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.6 25.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.6 5.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.6 4.0 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.6 5.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.6 7.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.6 1.7 GO:0098770 FBXO family protein binding(GO:0098770)
0.5 1.6 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.5 3.8 GO:0004849 uridine kinase activity(GO:0004849)
0.5 3.7 GO:0008097 5S rRNA binding(GO:0008097)
0.5 4.3 GO:0001849 complement component C1q binding(GO:0001849)
0.5 4.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.5 4.9 GO:0051434 BH3 domain binding(GO:0051434)
0.5 1.5 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.5 2.4 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.5 4.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.5 2.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.5 2.3 GO:0070573 metallodipeptidase activity(GO:0070573)
0.5 8.2 GO:0008301 DNA binding, bending(GO:0008301)
0.5 5.0 GO:0042731 PH domain binding(GO:0042731)
0.4 82.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 3.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.4 1.7 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.4 10.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.4 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.4 1.6 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.4 2.8 GO:0019211 phosphatase activator activity(GO:0019211)
0.4 18.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.4 3.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.4 20.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 1.6 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.4 15.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.4 1.5 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.4 3.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.4 3.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.4 1.8 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.4 6.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.4 1.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.4 35.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 3.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 1.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.3 1.7 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.3 2.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 12.5 GO:0008198 ferrous iron binding(GO:0008198)
0.3 2.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.3 2.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.3 1.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.3 4.7 GO:0050897 cobalt ion binding(GO:0050897)
0.3 4.7 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.3 1.9 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.3 1.5 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.3 4.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.3 1.8 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.3 8.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 1.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.3 1.8 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.3 0.9 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.3 4.6 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.3 4.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.3 2.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 6.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 1.1 GO:0050436 microfibril binding(GO:0050436)
0.3 2.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.3 1.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 1.9 GO:0019808 polyamine binding(GO:0019808)
0.3 8.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.3 6.3 GO:0043274 phospholipase binding(GO:0043274)
0.3 13.6 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.3 0.8 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.3 1.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 1.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 1.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 3.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 6.3 GO:0031005 filamin binding(GO:0031005)
0.2 8.6 GO:0070717 poly-purine tract binding(GO:0070717)
0.2 2.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 3.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 16.7 GO:0043022 ribosome binding(GO:0043022)
0.2 2.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.2 5.2 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.2 4.9 GO:0070628 proteasome binding(GO:0070628)
0.2 6.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 5.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 2.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 0.2 GO:0070052 collagen V binding(GO:0070052)
0.2 4.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 0.6 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 5.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 10.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 1.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 14.6 GO:0030507 spectrin binding(GO:0030507)
0.2 1.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 2.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 5.1 GO:0019843 rRNA binding(GO:0019843)
0.2 5.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 4.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 2.3 GO:0015266 protein channel activity(GO:0015266)
0.2 2.5 GO:0030275 LRR domain binding(GO:0030275)
0.2 3.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 2.0 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.2 1.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 0.9 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 2.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 2.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 4.6 GO:0070410 co-SMAD binding(GO:0070410)
0.2 0.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 2.0 GO:0035325 Toll-like receptor binding(GO:0035325)
0.2 1.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 3.8 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.7 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 6.9 GO:0030552 cAMP binding(GO:0030552)
0.1 5.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.3 GO:0004568 chitinase activity(GO:0004568)
0.1 2.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612) clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 1.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.8 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 5.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 11.5 GO:0002039 p53 binding(GO:0002039)
0.1 6.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.1 2.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 2.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 20.7 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 2.9 GO:0016594 glycine binding(GO:0016594)
0.1 3.7 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 2.3 GO:0005521 lamin binding(GO:0005521)
0.1 0.4 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.1 4.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 14.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 0.4 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.7 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.3 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.3 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.1 1.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.2 GO:0043236 laminin binding(GO:0043236)
0.1 1.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.7 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 5.3 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 2.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 4.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 0.8 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.9 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.9 GO:0036310 annealing helicase activity(GO:0036310)
0.1 2.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 4.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.6 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 0.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 2.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.0 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958) cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 6.0 GO:0030276 clathrin binding(GO:0030276)
0.1 0.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.8 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.1 0.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.2 GO:0032183 SUMO binding(GO:0032183)
0.1 0.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 10.0 GO:0005178 integrin binding(GO:0005178)
0.1 1.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.3 GO:0051373 FATZ binding(GO:0051373)
0.1 1.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.2 GO:0031177 phosphopantetheine binding(GO:0031177)
0.1 2.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 4.6 GO:0097110 scaffold protein binding(GO:0097110)
0.1 2.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.2 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 2.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.8 GO:0034061 DNA polymerase activity(GO:0034061)
0.1 3.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 3.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 4.2 GO:0019894 kinesin binding(GO:0019894)
0.1 1.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 5.6 GO:0051087 chaperone binding(GO:0051087)
0.1 6.3 GO:0002020 protease binding(GO:0002020)
0.1 3.6 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.1 3.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 1.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 4.0 GO:0005518 collagen binding(GO:0005518)
0.1 1.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 1.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.9 GO:0000146 microfilament motor activity(GO:0000146)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 3.2 GO:0032947 protein complex scaffold(GO:0032947)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.3 GO:0000049 tRNA binding(GO:0000049)
0.0 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 8.7 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 1.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 2.2 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 22.3 GO:0003682 chromatin binding(GO:0003682)
0.0 5.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 17.2 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 1.4 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 2.0 GO:0019210 kinase inhibitor activity(GO:0019210)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 5.5 GO:0045296 cadherin binding(GO:0045296)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 5.8 GO:0005549 odorant binding(GO:0005549)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.9 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.4 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.7 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.3 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 1.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 45.4 PID ATR PATHWAY ATR signaling pathway
0.6 1.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.5 25.8 PID AURORA A PATHWAY Aurora A signaling
0.5 18.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.4 24.1 PID BMP PATHWAY BMP receptor signaling
0.4 14.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4 20.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.4 31.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 18.9 PID AURORA B PATHWAY Aurora B signaling
0.4 13.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.4 5.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.3 8.9 PID IL5 PATHWAY IL5-mediated signaling events
0.3 12.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.3 11.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 2.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 11.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 21.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 5.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 7.3 PID IL27 PATHWAY IL27-mediated signaling events
0.2 5.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 14.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 21.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 9.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 4.7 PID MYC PATHWAY C-MYC pathway
0.2 1.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 10.3 PID P53 REGULATION PATHWAY p53 pathway
0.1 4.6 PID CONE PATHWAY Visual signal transduction: Cones
0.1 5.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 7.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 4.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 5.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 9.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 4.9 ST GA13 PATHWAY G alpha 13 Pathway
0.1 6.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 1.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 4.2 PID TNF PATHWAY TNF receptor signaling pathway
0.1 1.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 3.0 PID RAS PATHWAY Regulation of Ras family activation
0.1 4.5 PID LKB1 PATHWAY LKB1 signaling events
0.1 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 1.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 3.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 0.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 3.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.3 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.4 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 5.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 4.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
1.2 23.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
1.1 18.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.0 25.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.8 104.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.8 24.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.7 21.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.7 45.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.6 33.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.6 10.0 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.6 1.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.5 11.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.5 2.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.5 15.1 REACTOME KINESINS Genes involved in Kinesins
0.5 13.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.4 12.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.4 13.2 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.4 5.8 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.4 6.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 7.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.4 11.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.4 9.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 33.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 18.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 4.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.3 20.6 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.3 2.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.3 5.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 5.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3 4.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 7.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3 5.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.3 5.6 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.3 4.3 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.2 4.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 4.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 5.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 26.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.2 12.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 2.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 11.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 4.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 6.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 1.6 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.2 4.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.2 3.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 2.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 20.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 5.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 4.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 6.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 3.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 4.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 2.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 3.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 5.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 8.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 5.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 1.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 4.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 5.5 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 5.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 11.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 3.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 3.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 5.7 REACTOME TRANSLATION Genes involved in Translation
0.1 1.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 11.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.5 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.0 0.7 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 2.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.0 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 4.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling