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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Pknox2_Pknox1

Z-value: 0.86

Motif logo

Transcription factors associated with Pknox2_Pknox1

Gene Symbol Gene ID Gene Info
ENSMUSG00000035934.17 Pknox2
ENSMUSG00000006705.14 Pknox1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pknox1mm39_v1_chr17_+_31783708_317838470.501.9e-03Click!
Pknox2mm39_v1_chr9_-_37058590_37058703-0.115.1e-01Click!

Activity profile of Pknox2_Pknox1 motif

Sorted Z-values of Pknox2_Pknox1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pknox2_Pknox1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_123032821 3.97 ENSMUST00000219619.2
ENSMUST00000020334.9
ubiquitin specific peptidase 15
chr7_-_131012202 3.14 ENSMUST00000207243.2
ENSMUST00000128432.3
ENSMUST00000121033.8
ENSMUST00000046306.15
IKAROS family zinc finger 5
chr11_+_23206001 2.91 ENSMUST00000020538.13
ENSMUST00000109551.8
ENSMUST00000102870.8
ENSMUST00000102869.8
exportin 1
chr1_-_66984178 2.44 ENSMUST00000027151.12
myosin, light polypeptide 1
chr17_-_24360516 2.26 ENSMUST00000115411.8
ENSMUST00000115409.9
ENSMUST00000115407.9
ENSMUST00000102927.10
3-phosphoinositide dependent protein kinase 1
chr9_+_113760002 2.04 ENSMUST00000084885.12
ENSMUST00000009885.14
upstream binding protein 1
chr7_-_48530777 1.91 ENSMUST00000058745.15
E2F transcription factor 8
chr19_-_9876815 1.80 ENSMUST00000237147.2
ENSMUST00000025562.9
inner centromere protein
chr9_+_113760376 1.73 ENSMUST00000214095.2
ENSMUST00000116492.3
ENSMUST00000216558.2
upstream binding protein 1
chr7_-_48531344 1.73 ENSMUST00000119223.2
E2F transcription factor 8
chr1_-_66984521 1.62 ENSMUST00000160100.2
myosin, light polypeptide 1
chr19_-_9876745 1.62 ENSMUST00000237725.2
inner centromere protein
chr5_+_124585244 1.40 ENSMUST00000198451.2
lysine methyltransferase 5A
chr2_+_160487801 1.35 ENSMUST00000109468.3
topoisomerase (DNA) I
chr10_+_7668655 1.21 ENSMUST00000015901.11
peptidylprolyl isomerase (cyclophilin)-like 4
chr2_-_132420074 1.21 ENSMUST00000110136.8
ENSMUST00000124107.8
ENSMUST00000060955.12
glycerophosphocholine phosphodiesterase 1
chr11_-_79971750 1.15 ENSMUST00000103233.10
ENSMUST00000061283.15
cytokine receptor-like factor 3
chr11_-_4544751 1.11 ENSMUST00000109943.10
myotubularin related protein 3
chr1_+_134110142 0.98 ENSMUST00000082060.10
ENSMUST00000153856.8
ENSMUST00000133701.8
ENSMUST00000132873.8
chitinase-like 1
chr2_-_132420047 0.96 ENSMUST00000028822.14
glycerophosphocholine phosphodiesterase 1
chr2_-_132420164 0.96 ENSMUST00000110142.8
glycerophosphocholine phosphodiesterase 1
chr10_-_63174801 0.94 ENSMUST00000020257.13
ENSMUST00000177694.8
ENSMUST00000105442.3
sirtuin 1
chrX_-_108056995 0.94 ENSMUST00000033597.9
high-mobility group nucleosome binding domain 5
chr9_-_62888156 0.89 ENSMUST00000098651.6
ENSMUST00000214830.2
protein inhibitor of activated STAT 1
chr3_-_108352499 0.89 ENSMUST00000090553.12
ENSMUST00000153499.2
seryl-aminoacyl-tRNA synthetase
chr18_+_63841756 0.88 ENSMUST00000072726.7
ENSMUST00000235648.2
ENSMUST00000236879.2
WD repeat domain 7
chr7_-_141649003 0.87 ENSMUST00000039926.10
dual specificity phosphatase 8
chr9_+_123195986 0.84 ENSMUST00000038863.9
ENSMUST00000216843.2
leucyl-tRNA synthetase, mitochondrial
chr7_-_131012051 0.83 ENSMUST00000154602.8
ENSMUST00000142349.3
IKAROS family zinc finger 5
chr5_+_34919078 0.81 ENSMUST00000080036.3
huntingtin
chr1_+_156193607 0.81 ENSMUST00000102782.4
predicted gene 2000
chr17_-_48739874 0.80 ENSMUST00000046549.5
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr2_+_30306116 0.80 ENSMUST00000113601.10
ENSMUST00000113603.10
protein phosphatase 2 protein activator
chr3_+_51323383 0.78 ENSMUST00000029303.13
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr11_-_46203047 0.75 ENSMUST00000129474.2
ENSMUST00000093166.11
ENSMUST00000165599.9
cytoplasmic FMR1 interacting protein 2
chr8_+_89423645 0.73 ENSMUST00000043526.15
ENSMUST00000211554.2
ENSMUST00000209532.2
ENSMUST00000209559.2
CYLD lysine 63 deubiquitinase
chr11_+_117877118 0.73 ENSMUST00000132676.8
phosphatidylglycerophosphate synthase 1
chr1_+_134109888 0.72 ENSMUST00000156873.8
chitinase-like 1
chr3_+_116388600 0.70 ENSMUST00000198386.5
ENSMUST00000198311.5
ENSMUST00000197335.2
SAS-6 centriolar assembly protein
chr11_+_3152874 0.70 ENSMUST00000179770.8
ENSMUST00000110048.8
eukaryotic translation initiation factor 4E nuclear import factor 1
chr3_-_108352459 0.69 ENSMUST00000132467.8
ENSMUST00000102625.11
seryl-aminoacyl-tRNA synthetase
chr1_+_85721132 0.68 ENSMUST00000113360.8
ENSMUST00000126962.3
calcium binding protein 39
chr18_+_49965689 0.68 ENSMUST00000180611.8
Dmx-like 1
chr4_+_126915104 0.68 ENSMUST00000030623.8
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr5_+_93416091 0.68 ENSMUST00000121127.2
cyclin G2
chr10_-_123032881 0.67 ENSMUST00000220377.2
ubiquitin specific peptidase 15
chr13_+_63963054 0.67 ENSMUST00000021926.13
ENSMUST00000067821.13
ENSMUST00000144763.2
ENSMUST00000021925.14
ENSMUST00000238465.2
excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2
chr2_-_76812799 0.66 ENSMUST00000011934.13
ENSMUST00000099981.10
ENSMUST00000099980.10
ENSMUST00000111882.9
ENSMUST00000140091.8
titin
chr6_+_38086190 0.66 ENSMUST00000031851.5
transmembrane protein 213
chr3_+_95139598 0.65 ENSMUST00000107200.8
ENSMUST00000107199.2
CDC42 small effector 1
chr5_+_35146727 0.63 ENSMUST00000114284.8
regulator of G-protein signaling 12
chr16_-_10993919 0.63 ENSMUST00000142389.3
ENSMUST00000138185.9
zinc finger CCCH type containing 7 A
chr1_-_87029312 0.63 ENSMUST00000113270.3
alkaline phosphatase, intestinal
chr3_-_100591906 0.62 ENSMUST00000130066.2
mannosidase, alpha, class 1A, member 2
chr6_-_106777014 0.60 ENSMUST00000013882.10
ENSMUST00000113239.10
cereblon
chr13_-_64300964 0.59 ENSMUST00000059817.12
ENSMUST00000117241.2
zinc finger protein 367
chr9_+_67747668 0.56 ENSMUST00000077879.7
vacuolar protein sorting 13C
chr4_-_108158242 0.56 ENSMUST00000043616.7
zyg-ll family member B, cell cycle regulator
chr16_+_91188609 0.55 ENSMUST00000160764.2
predicted gene 21970
chr3_+_51324022 0.53 ENSMUST00000192419.6
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr10_-_117546660 0.51 ENSMUST00000020408.16
ENSMUST00000105263.9
transformed mouse 3T3 cell double minute 2
chr7_+_45084257 0.51 ENSMUST00000003964.17
glycogen synthase 1, muscle
chr5_+_35146880 0.49 ENSMUST00000114285.8
regulator of G-protein signaling 12
chr17_-_25155868 0.49 ENSMUST00000115228.9
ENSMUST00000117509.8
ENSMUST00000121723.8
ENSMUST00000119115.8
ENSMUST00000121787.8
ENSMUST00000088345.12
ENSMUST00000120035.8
ENSMUST00000115229.10
ENSMUST00000178969.8
mitogen-activated protein kinase 8 interacting protein 3
chr6_-_38086484 0.47 ENSMUST00000114908.5
ATPase, H+ transporting, lysosomal V0 subunit A4
chr7_-_45084012 0.47 ENSMUST00000107771.12
ENSMUST00000211666.2
RuvB-like protein 2
chr7_-_45083688 0.46 ENSMUST00000210439.2
RuvB-like protein 2
chr16_-_90808196 0.44 ENSMUST00000121759.8
synaptojanin 1
chr1_+_156386414 0.44 ENSMUST00000166172.9
ENSMUST00000027888.13
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr7_+_45084300 0.44 ENSMUST00000211150.2
glycogen synthase 1, muscle
chr11_+_78215026 0.42 ENSMUST00000102478.4
aldolase C, fructose-bisphosphate
chr4_+_11758147 0.41 ENSMUST00000029871.12
ENSMUST00000108303.2
cadherin 17
chr7_+_98352298 0.37 ENSMUST00000033009.16
THAP domain containing 12
chr13_+_109822527 0.37 ENSMUST00000074103.12
phosphodiesterase 4D, cAMP specific
chr2_+_163837423 0.36 ENSMUST00000131288.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr17_+_30845909 0.35 ENSMUST00000236140.2
ENSMUST00000236118.2
ENSMUST00000235390.2
dynein, axonemal, heavy chain 8
chr8_-_112248619 0.35 ENSMUST00000211981.2
ENSMUST00000034437.8
ENSMUST00000038193.15
WD repeat domain 59
chr5_-_122917341 0.34 ENSMUST00000198257.5
ENSMUST00000199599.2
ENSMUST00000196742.2
ENSMUST00000200109.5
ENSMUST00000111668.8
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr3_-_95139472 0.34 ENSMUST00000196025.5
ENSMUST00000198948.5
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
chr8_+_26091607 0.33 ENSMUST00000155861.8
nuclear receptor binding SET domain protein 3
chr8_-_81741495 0.32 ENSMUST00000042724.8
ubiquitin specific peptidase 38
chr3_+_137570248 0.32 ENSMUST00000041045.14
H2A.Z variant histone 1
chr3_-_27764571 0.32 ENSMUST00000046157.10
fibronectin type III domain containing 3B
chr3_-_27764522 0.31 ENSMUST00000195008.6
fibronectin type III domain containing 3B
chr3_-_51468236 0.30 ENSMUST00000037141.9
SET domain containing (lysine methyltransferase) 7
chr2_+_152753231 0.29 ENSMUST00000028970.8
myosin, light polypeptide kinase 2, skeletal muscle
chr10_-_62486948 0.28 ENSMUST00000020270.6
DExD box helicase 50
chr2_-_31031814 0.27 ENSMUST00000073879.12
ENSMUST00000100208.9
ENSMUST00000100207.9
ENSMUST00000113555.8
ENSMUST00000075326.11
ENSMUST00000113552.9
ENSMUST00000136181.8
ENSMUST00000113564.9
ENSMUST00000113562.9
ENSMUST00000113560.8
formin binding protein 1
chr5_-_138617952 0.27 ENSMUST00000063262.11
ENSMUST00000085852.11
ENSMUST00000110905.9
zinc finger protein 68
chr11_+_83855245 0.26 ENSMUST00000049714.15
ENSMUST00000092834.12
ENSMUST00000183714.8
ENSMUST00000183456.8
synergin, gamma
chr10_-_7668560 0.26 ENSMUST00000065124.2
glycoprotein integral membrane 1
chr11_-_97913420 0.26 ENSMUST00000103144.10
ENSMUST00000017552.13
ENSMUST00000092736.11
ENSMUST00000107562.2
calcium channel, voltage-dependent, beta 1 subunit
chr8_-_65146079 0.24 ENSMUST00000048967.9
carboxypeptidase E
chr13_+_46822992 0.24 ENSMUST00000099547.4
family with sequence similarity 8, member A1
chrX_+_48552803 0.24 ENSMUST00000130558.8
Rho GTPase activating protein 36
chr17_-_65920481 0.23 ENSMUST00000024897.10
vesicle-associated membrane protein, associated protein A
chr12_+_104094253 0.23 ENSMUST00000085052.3
serine (or cysteine) peptidase inhibitor, clade A, member 3B
chr10_+_82534841 0.21 ENSMUST00000020478.14
host cell factor C2
chr17_-_30845845 0.20 ENSMUST00000235547.2
ENSMUST00000188852.2
glyoxalase 1
RIKEN cDNA 1700097N02 gene
chr11_+_78717398 0.20 ENSMUST00000147875.9
ENSMUST00000141321.2
LYR motif containing 9
chr7_+_24920840 0.18 ENSMUST00000055604.6
zinc finger protein 526
chr1_-_74627264 0.18 ENSMUST00000066986.13
zinc finger protein 142
chr3_+_96577447 0.18 ENSMUST00000048427.9
ankyrin repeat domain 35
chr5_+_110434172 0.18 ENSMUST00000007296.12
ENSMUST00000112482.2
polymerase (DNA directed), epsilon
chr9_+_21336300 0.17 ENSMUST00000172482.8
ENSMUST00000174050.8
dynamin 2
chr1_+_135980639 0.17 ENSMUST00000112064.8
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr1_+_135980488 0.16 ENSMUST00000160641.8
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr2_+_111610658 0.16 ENSMUST00000054004.2
olfactory receptor 1302
chr1_+_106866678 0.15 ENSMUST00000112724.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12
chr17_+_29768757 0.15 ENSMUST00000048677.9
ENSMUST00000150388.3
TBC1 domain family, member 22B
predicted gene, 28052
chr14_+_55252911 0.15 ENSMUST00000022815.10
neuroguidin, EIF4E binding protein
chrX_-_101548965 0.14 ENSMUST00000087916.11
histone deacetylase 8
chr16_-_89940652 0.13 ENSMUST00000114124.9
T cell lymphoma invasion and metastasis 1
chr13_+_76532470 0.13 ENSMUST00000125209.8
multiple C2 domains, transmembrane 1
chr11_+_55095144 0.13 ENSMUST00000108872.9
ENSMUST00000147506.8
ENSMUST00000020499.14
solute carrier family 36 (proton/amino acid symporter), member 1
chr11_-_114686712 0.12 ENSMUST00000000206.4
BTB (POZ) domain containing 17
chr17_-_31738901 0.12 ENSMUST00000171291.2
ENSMUST00000237807.2
WD repeat domain 4
chr12_-_108860042 0.12 ENSMUST00000109848.10
tryptophanyl-tRNA synthetase
chr6_+_135042649 0.12 ENSMUST00000050104.8
G protein-coupled receptor, family C, group 5, member A
chr5_+_67765216 0.11 ENSMUST00000087241.7
shisa family member 3
chr2_+_162829422 0.10 ENSMUST00000117123.2
serum/glucocorticoid regulated kinase 2
chr16_+_55794244 0.10 ENSMUST00000050248.9
zinc finger and BTB domain containing 11
chr12_-_85420684 0.09 ENSMUST00000222585.2
transmembrane p24 trafficking protein 10
chr1_+_87052668 0.08 ENSMUST00000044878.4
alkaline phosphatase 3, intestine, not Mn requiring
chr2_+_129854256 0.08 ENSMUST00000110299.3
transglutaminase 3, E polypeptide
chr10_-_129738595 0.08 ENSMUST00000071557.2
olfactory receptor 815
chr9_+_68561042 0.08 ENSMUST00000034766.14
RAR-related orphan receptor alpha
chr9_+_107805647 0.08 ENSMUST00000085073.2
actin-like 11
chr1_+_135980508 0.08 ENSMUST00000112068.10
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr4_+_133970973 0.07 ENSMUST00000135228.8
ENSMUST00000144222.8
ENSMUST00000143448.8
ENSMUST00000125921.8
ENSMUST00000122952.8
ENSMUST00000131447.2
RIKEN cDNA E130218I03 gene
chr7_-_12743720 0.07 ENSMUST00000210282.2
ENSMUST00000172240.2
ENSMUST00000051390.9
ENSMUST00000209997.2
zinc finger and BTB domain containing 45
chr11_-_20781009 0.07 ENSMUST00000047028.9
lectin, galactoside binding-like
chr1_+_156443472 0.06 ENSMUST00000190749.2
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr17_+_30843328 0.06 ENSMUST00000170651.2
dynein, axonemal, heavy chain 8
chr15_+_99600475 0.05 ENSMUST00000228984.2
ENSMUST00000229845.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr2_+_162829250 0.05 ENSMUST00000018012.14
serum/glucocorticoid regulated kinase 2
chr5_+_24679154 0.04 ENSMUST00000199856.2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr4_-_119075362 0.04 ENSMUST00000212054.2
ENSMUST00000030394.3
transmembrane protein 269
chr8_-_116434517 0.03 ENSMUST00000109104.2
avian musculoaponeurotic fibrosarcoma oncogene homolog
chr3_-_84178089 0.03 ENSMUST00000054990.11
tripartite motif-containing 2
chr7_+_65693350 0.03 ENSMUST00000206065.2
predicted gene 45213
chr2_-_113588983 0.03 ENSMUST00000099575.4
gremlin 1, DAN family BMP antagonist
chr9_+_21336198 0.03 ENSMUST00000165766.9
ENSMUST00000173397.8
ENSMUST00000072362.14
ENSMUST00000091087.13
ENSMUST00000115404.11
dynamin 2
chr7_+_13132040 0.03 ENSMUST00000005791.14
calcium binding protein 5
chr10_-_29411857 0.02 ENSMUST00000092623.5
R-spondin 3
chr8_-_91860655 0.02 ENSMUST00000125257.3
AKT interacting protein
chr11_-_78277384 0.02 ENSMUST00000108294.2
forkhead box N1
chr12_+_108145802 0.01 ENSMUST00000221167.2
cyclin K
chr9_-_29874401 0.01 ENSMUST00000075069.11
neurotrimin
chr13_-_12121831 0.01 ENSMUST00000021750.15
ENSMUST00000170156.3
ENSMUST00000220597.2
ryanodine receptor 2, cardiac
chr6_-_71239216 0.01 ENSMUST00000129630.3
ENSMUST00000114186.9
ENSMUST00000074301.10
SET and MYND domain containing 1
chrX_+_13499008 0.00 ENSMUST00000096492.4
G protein-coupled receptor 34
chr5_+_57879201 0.00 ENSMUST00000199310.2
protocadherin 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.9 4.6 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.5 1.6 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.3 0.9 GO:2000612 regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.3 2.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 0.8 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.3 0.8 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.2 1.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.2 3.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 0.8 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
0.2 0.6 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2 0.7 GO:0043056 forward locomotion(GO:0043056)
0.2 0.9 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 1.3 GO:0006265 DNA topological change(GO:0006265)
0.1 0.4 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 1.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 1.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.5 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 0.7 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 0.3 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 1.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 2.3 GO:0006972 hyperosmotic response(GO:0006972)
0.1 1.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 1.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.3 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.1 0.7 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.2 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.1 0.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.2 GO:0045004 DNA replication proofreading(GO:0045004)
0.1 0.7 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 0.9 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.4 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:1904266 regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.6 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 1.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.3 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 4.3 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.7 GO:0007099 centriole replication(GO:0007099)
0.0 3.4 GO:0000910 cytokinesis(GO:0000910)
0.0 4.1 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.7 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.0 GO:0030578 PML body organization(GO:0030578)
0.0 0.6 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.9 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.0 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257)
0.0 0.7 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.9 GO:0006749 glutathione metabolic process(GO:0006749)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 GO:0000801 central element(GO:0000801)
0.2 0.7 GO:0043291 RAVE complex(GO:0043291)
0.2 2.9 GO:0005642 annulate lamellae(GO:0005642)
0.2 1.3 GO:0031298 replication fork protection complex(GO:0031298)
0.2 0.9 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.3 GO:0031415 NatA complex(GO:0031415)
0.1 0.9 GO:0097255 R2TP complex(GO:0097255)
0.1 0.7 GO:0098536 deuterosome(GO:0098536)
0.1 0.7 GO:0042382 paraspeckles(GO:0042382)
0.1 0.7 GO:0097542 ciliary tip(GO:0097542)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 4.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.9 GO:0097440 apical dendrite(GO:0097440)
0.0 0.4 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.8 3.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.5 1.6 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.4 1.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.3 0.9 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.3 0.9 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.3 0.8 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.2 2.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 0.8 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.2 2.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 1.7 GO:0008061 chitin binding(GO:0008061)
0.1 1.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.9 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.8 GO:0034452 dynactin binding(GO:0034452)
0.1 0.4 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.6 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 1.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.7 GO:0031433 telethonin binding(GO:0031433)
0.1 0.8 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 1.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.4 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 6.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.4 PID AURORA B PATHWAY Aurora B signaling
0.1 2.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 4.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 2.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.8 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 3.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 3.5 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation