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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Pou5f1

Z-value: 2.13

Motif logo

Transcription factors associated with Pou5f1

Gene Symbol Gene ID Gene Info
ENSMUSG00000024406.17 Pou5f1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou5f1mm39_v1_chr17_+_35816915_358169680.095.8e-01Click!

Activity profile of Pou5f1 motif

Sorted Z-values of Pou5f1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou5f1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_69496655 14.01 ENSMUST00000047889.13
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr10_+_75784126 9.00 ENSMUST00000000926.3
pre-B lymphocyte gene 3
chr17_+_41121979 8.61 ENSMUST00000024721.8
ENSMUST00000233740.2
Rhesus blood group-associated A glycoprotein
chr6_-_67014383 8.21 ENSMUST00000043098.9
growth arrest and DNA-damage-inducible 45 alpha
chr11_-_106205320 7.58 ENSMUST00000167143.2
CD79B antigen
chr8_+_94899292 7.40 ENSMUST00000034214.8
ENSMUST00000212806.2
metallothionein 2
chr11_+_95227836 6.81 ENSMUST00000037502.7
family with sequence similarity 117, member A
chr1_-_132318039 6.70 ENSMUST00000132435.2
transmembrane and coiled-coil domains 2
chr7_-_4815542 6.17 ENSMUST00000079496.9
ubiquitin-conjugating enzyme E2S
chr17_+_28426752 5.95 ENSMUST00000002327.6
ENSMUST00000233560.2
ENSMUST00000233958.2
ENSMUST00000233170.2
differentially expressed in FDCP 6
chr7_+_28682253 5.64 ENSMUST00000085835.8
mitogen-activated protein kinase kinase kinase kinase 1
chr17_+_27775637 5.56 ENSMUST00000117254.9
ENSMUST00000231243.2
ENSMUST00000231358.2
ENSMUST00000118570.2
ENSMUST00000231796.2
high mobility group AT-hook 1
chr6_-_83513222 5.48 ENSMUST00000075161.12
actin, gamma 2, smooth muscle, enteric
chr17_+_27775613 5.43 ENSMUST00000231780.2
ENSMUST00000232253.2
ENSMUST00000232552.2
ENSMUST00000117600.9
high mobility group AT-hook 1
chr17_+_27775471 5.41 ENSMUST00000118599.9
ENSMUST00000232265.2
ENSMUST00000232013.2
ENSMUST00000114888.11
ENSMUST00000231874.2
ENSMUST00000119486.9
ENSMUST00000231825.2
ENSMUST00000231866.2
high mobility group AT-hook 1
chr12_-_36092475 5.21 ENSMUST00000020896.17
tetraspanin 13
chr4_-_152561896 4.76 ENSMUST00000238738.2
ENSMUST00000162017.3
ENSMUST00000030768.10
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr15_-_66703471 4.74 ENSMUST00000164163.8
src-like adaptor
chr6_-_67014348 4.67 ENSMUST00000204369.2
growth arrest and DNA-damage-inducible 45 alpha
chr6_-_68713748 4.52 ENSMUST00000183936.2
ENSMUST00000196863.2
immunoglobulin kappa chain variable 19-93
chr6_+_29694181 4.52 ENSMUST00000046750.14
ENSMUST00000115250.4
tetraspanin 33
chr11_-_115968745 4.43 ENSMUST00000156545.2
ENSMUST00000075036.9
ENSMUST00000106451.8
unc-13 homolog D
chr1_-_45542442 4.38 ENSMUST00000086430.5
collagen, type V, alpha 2
chr1_+_91468409 4.26 ENSMUST00000027538.9
ENSMUST00000190484.7
ENSMUST00000186068.2
ankyrin repeat and SOCS box-containing 1
chr12_-_113542610 4.23 ENSMUST00000195468.6
ENSMUST00000103442.3
immunoglobulin heavy variable 5-2
chr2_-_152239966 4.23 ENSMUST00000063332.9
ENSMUST00000182625.2
SRY (sex determining region Y)-box 12
chr8_+_69333143 4.19 ENSMUST00000015712.15
lipoprotein lipase
chr4_-_63965161 4.15 ENSMUST00000107377.10
tenascin C
chr6_+_145067457 4.09 ENSMUST00000032396.13
lymphoid-restricted membrane protein
chr4_+_152123772 4.00 ENSMUST00000084116.13
ENSMUST00000103197.5
nucleolar protein 9
chr8_+_23464860 3.91 ENSMUST00000110688.9
ENSMUST00000121802.9
ankyrin 1, erythroid
chr10_+_115653152 3.84 ENSMUST00000080630.11
ENSMUST00000179196.3
ENSMUST00000035563.15
tetraspanin 8
chr4_-_128699838 3.76 ENSMUST00000106072.9
ENSMUST00000170934.3
zinc finger protein 362
chr14_-_20319242 3.69 ENSMUST00000024155.9
potassium channel, subfamily K, member 16
chr6_-_67014191 3.64 ENSMUST00000204282.2
growth arrest and DNA-damage-inducible 45 alpha
chr6_-_56878854 3.61 ENSMUST00000101367.9
5'-nucleotidase, cytosolic III
chr10_+_79762858 3.58 ENSMUST00000019708.12
ENSMUST00000105377.8
AT rich interactive domain 3A (BRIGHT-like)
chr2_+_90927053 3.50 ENSMUST00000132741.3
spleen focus forming virus (SFFV) proviral integration oncogene
chr8_+_23548541 3.45 ENSMUST00000173248.8
ankyrin 1, erythroid
chr8_+_71069476 3.41 ENSMUST00000052437.6
leucine rich repeat containing 25
chr6_-_83513184 3.37 ENSMUST00000205926.2
actin, gamma 2, smooth muscle, enteric
chr12_-_113552322 3.36 ENSMUST00000103443.3
immunoglobulin heavy variable 2-2
chr17_-_35827676 3.28 ENSMUST00000160885.2
ENSMUST00000159009.2
ENSMUST00000161012.8
transcription factor 19
chr1_+_87603952 3.24 ENSMUST00000170300.8
ENSMUST00000167032.2
inositol polyphosphate-5-phosphatase D
chr19_-_34231600 3.24 ENSMUST00000238147.2
actin, alpha 2, smooth muscle, aorta
chr7_-_44180700 3.17 ENSMUST00000205506.2
Spi-B transcription factor (Spi-1/PU.1 related)
chr11_+_44508137 3.15 ENSMUST00000109268.2
ENSMUST00000101326.10
ENSMUST00000081265.12
early B cell factor 1
chr10_-_88520877 3.15 ENSMUST00000138734.2
Spi-C transcription factor (Spi-1/PU.1 related)
chr13_-_22017677 3.07 ENSMUST00000081342.7
H2A clustered histone 24
chr14_-_67953035 3.06 ENSMUST00000163100.8
ENSMUST00000132705.8
ENSMUST00000124045.3
cell division cycle associated 2
chr6_+_68247469 3.01 ENSMUST00000103321.3
immunoglobulin kappa variable 1-110
chr19_+_8919228 3.00 ENSMUST00000096240.3
metastasis-associated gene family, member 2
chr12_-_113589576 3.00 ENSMUST00000103446.2
immunoglobulin heavy variable 5-6
chr7_+_110372860 2.99 ENSMUST00000143786.2
adenosine monophosphate deaminase 3
chr13_-_29137673 2.94 ENSMUST00000067230.6
SRY (sex determining region Y)-box 4
chr19_+_6450553 2.92 ENSMUST00000146831.8
ENSMUST00000035716.15
ENSMUST00000138555.8
ENSMUST00000167240.8
RAS, guanyl releasing protein 2
chr11_-_115968576 2.91 ENSMUST00000106450.8
unc-13 homolog D
chr11_+_98632631 2.89 ENSMUST00000064187.12
thyroid hormone receptor alpha
chr14_+_71127540 2.87 ENSMUST00000022699.10
glial cell line derived neurotrophic factor family receptor alpha 2
chr5_+_137628377 2.86 ENSMUST00000175968.8
leucine-rich repeats and calponin homology (CH) domain containing 4
chr5_+_137627431 2.85 ENSMUST00000176667.8
leucine-rich repeats and calponin homology (CH) domain containing 4
chr6_+_67586695 2.85 ENSMUST00000103303.3
immunoglobulin kappa variable 1-135
chr12_-_113823290 2.85 ENSMUST00000103459.5
immunoglobulin heavy variable 5-17
chr2_+_72306503 2.83 ENSMUST00000102691.11
ENSMUST00000157019.2
cell division cycle associated 7
chrX_+_92718695 2.83 ENSMUST00000045898.4
phosphate cytidylyltransferase 1, choline, beta isoform
chr12_-_114252202 2.75 ENSMUST00000195124.6
ENSMUST00000103481.3
immunoglobulin heavy variable 3-6
chr17_+_28426831 2.72 ENSMUST00000233264.2
differentially expressed in FDCP 6
chr7_+_121888520 2.71 ENSMUST00000064989.12
ENSMUST00000064921.5
protein kinase C, beta
chr5_+_76988444 2.70 ENSMUST00000120639.9
ENSMUST00000163347.8
ENSMUST00000121851.2
capping protein inhibiting regulator of actin
chr11_+_58845502 2.70 ENSMUST00000108817.5
ENSMUST00000047697.12
H2A.W histone
tripartite motif-containing 17
chr11_-_3454766 2.66 ENSMUST00000044507.12
inositol polyphosphate 5-phosphatase J
chr12_-_114443071 2.65 ENSMUST00000103492.2
immunoglobulin heavy variable 10-1
chr17_-_35383867 2.65 ENSMUST00000025253.12
proline-rich coiled-coil 2A
chr13_+_97377604 2.63 ENSMUST00000041623.9
ectodermal-neural cortex 1
chr12_-_113561594 2.62 ENSMUST00000103444.3
immunoglobulin heavy variable 5-4
chr5_+_66833434 2.62 ENSMUST00000031131.11
ubiquitin carboxy-terminal hydrolase L1
chr1_+_91468266 2.59 ENSMUST00000086843.11
ankyrin repeat and SOCS box-containing 1
chr11_+_83741689 2.58 ENSMUST00000108114.9
HNF1 homeobox B
chr11_+_83741657 2.54 ENSMUST00000021016.10
HNF1 homeobox B
chr12_-_101784727 2.51 ENSMUST00000222587.2
fibulin 5
chr17_+_29709723 2.41 ENSMUST00000024811.9
proviral integration site 1
chr16_+_17051423 2.34 ENSMUST00000090190.14
ENSMUST00000232082.2
ENSMUST00000232426.2
hypermethylated in cancer 2
predicted gene, 49573
chr6_-_69792108 2.33 ENSMUST00000103367.3
immunoglobulin kappa variable 12-44
chr5_-_123126550 2.28 ENSMUST00000086200.11
ENSMUST00000156474.8
lysine (K)-specific demethylase 2B
chr14_-_103220066 2.16 ENSMUST00000184744.2
potassium channel tetramerisation domain containing 12
chr7_+_110373447 2.15 ENSMUST00000147587.2
adenosine monophosphate deaminase 3
chr6_+_68233361 2.14 ENSMUST00000103320.3
immunoglobulin kappa variable 14-111
chr11_+_98632696 2.14 ENSMUST00000103139.11
thyroid hormone receptor alpha
chr10_-_79744726 2.13 ENSMUST00000165684.8
ENSMUST00000164705.8
ENSMUST00000105378.9
ENSMUST00000170409.2
mediator complex subunit 16
chr6_-_70094604 2.11 ENSMUST00000103378.3
immunoglobulin kappa chain variable 8-30
chr6_+_136495784 2.10 ENSMUST00000032335.13
ENSMUST00000185724.7
activating transcription factor 7 interacting protein
chr12_-_101785307 2.09 ENSMUST00000021603.9
fibulin 5
chr11_-_115968373 2.08 ENSMUST00000174822.8
unc-13 homolog D
chr2_-_25086810 2.08 ENSMUST00000081869.7
torsin family 4, member A
chr5_-_123127148 2.06 ENSMUST00000046073.16
lysine (K)-specific demethylase 2B
chr2_+_160487801 2.05 ENSMUST00000109468.3
topoisomerase (DNA) I
chr10_-_117212860 2.04 ENSMUST00000069168.13
ENSMUST00000176686.8
cleavage and polyadenylation specific factor 6
chr17_-_28705055 2.04 ENSMUST00000233870.2
FK506 binding protein 5
chr4_-_43562397 2.03 ENSMUST00000030187.14
talin 1
chr7_-_44702269 2.01 ENSMUST00000057293.8
proline rich 12
chrX_-_165992311 2.01 ENSMUST00000112172.4
thymosin, beta 4, X chromosome
chr1_-_143879877 2.00 ENSMUST00000127206.8
regulator of G-protein signaling 2
chr6_+_68098030 1.99 ENSMUST00000103317.3
immunoglobulin kappa variable 1-117
chr12_-_114355789 1.99 ENSMUST00000103486.2
immunoglobulin heavy variable 6-3
chr17_-_28705082 1.98 ENSMUST00000079413.11
FK506 binding protein 5
chr12_-_114321838 1.98 ENSMUST00000125484.3
immunoglobulin heavy variable 13-2
chr3_+_5815863 1.97 ENSMUST00000192045.2
predicted pseudogene 8797
chr2_+_25070749 1.95 ENSMUST00000104999.4
Notch-regulated ankyrin repeat protein
chr5_+_64969679 1.94 ENSMUST00000166409.6
ENSMUST00000197879.2
Kruppel-like factor 3 (basic)
chr12_-_113649535 1.92 ENSMUST00000103449.4
ENSMUST00000195707.3
immunoglobulin heavy variable 2-5
chr14_+_71127882 1.91 ENSMUST00000227697.2
glial cell line derived neurotrophic factor family receptor alpha 2
chr9_+_86625694 1.90 ENSMUST00000179574.2
ENSMUST00000036426.13
protease, serine 35
chr11_+_98632953 1.90 ENSMUST00000153043.8
thyroid hormone receptor alpha
chr14_+_62529924 1.89 ENSMUST00000166879.8
ribonuclease H2, subunit B
chrX_-_165992145 1.88 ENSMUST00000112176.8
thymosin, beta 4, X chromosome
chr16_+_91526169 1.87 ENSMUST00000114001.8
ENSMUST00000113999.8
ENSMUST00000064797.12
ENSMUST00000114002.9
ENSMUST00000095909.10
ENSMUST00000056482.14
ENSMUST00000113996.8
intersectin 1 (SH3 domain protein 1A)
chr15_+_12824925 1.86 ENSMUST00000090292.13
drosha, ribonuclease type III
chr13_-_22227114 1.85 ENSMUST00000091741.6
H2A clustered histone 11
chr12_-_113860566 1.85 ENSMUST00000103474.5
immunoglobulin heavy variable 7-1
chr9_-_71803354 1.84 ENSMUST00000184448.8
transcription factor 12
chr12_-_114398864 1.83 ENSMUST00000103489.2
immunoglobulin heavy variable 6-6
chr15_+_6609322 1.81 ENSMUST00000090461.12
FYN binding protein
chr12_-_114752425 1.79 ENSMUST00000103510.2
immunoglobulin heavy variable 1-26
chr10_+_97315465 1.77 ENSMUST00000105287.11
decorin
chr6_-_69741999 1.76 ENSMUST00000103365.3
immunoglobulin kappa variable 12-46
chr8_+_121215155 1.75 ENSMUST00000034279.16
genetic suppressor element 1, coiled-coil protein
chr2_+_124452493 1.74 ENSMUST00000103239.10
ENSMUST00000103240.9
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr12_-_114487525 1.72 ENSMUST00000103495.3
immunoglobulin heavy variable V10-3
chr1_+_12788720 1.70 ENSMUST00000088585.10
sulfatase 1
chr6_+_68026941 1.68 ENSMUST00000103316.2
immunoglobulin kappa chain variable 9-120
chr15_+_12824901 1.65 ENSMUST00000169061.8
drosha, ribonuclease type III
chr12_-_113666198 1.62 ENSMUST00000103450.4
immunoglobulin heavy variable 5-12
chr1_-_91386976 1.58 ENSMUST00000069620.10
period circadian clock 2
chr17_+_28059036 1.56 ENSMUST00000071006.9
U1 small nuclear ribonucleoprotein C
chr4_+_128582519 1.55 ENSMUST00000106080.8
polyhomeotic 2
chr13_-_95661726 1.55 ENSMUST00000022185.10
coagulation factor II (thrombin) receptor-like 1
chr10_+_79763164 1.52 ENSMUST00000105376.2
AT rich interactive domain 3A (BRIGHT-like)
chrX_-_56384089 1.50 ENSMUST00000033468.11
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr2_-_25086770 1.50 ENSMUST00000142857.2
ENSMUST00000137920.2
torsin family 4, member A
chr19_-_40982576 1.49 ENSMUST00000117695.8
B cell linker
chr12_-_113575237 1.49 ENSMUST00000178229.3
immunoglobulin heavy variable 2-3
chr6_-_70237939 1.48 ENSMUST00000103386.3
immunoglobulin kappa variable 6-23
chr6_-_70292451 1.47 ENSMUST00000103387.3
immunoglobulin kappa variable 8-21
chr12_-_113790741 1.46 ENSMUST00000103457.3
ENSMUST00000192877.2
immunoglobulin heavy variable 5-15
chr11_-_5787743 1.46 ENSMUST00000109837.8
polymerase (DNA directed), mu
chr6_+_68279392 1.45 ENSMUST00000103322.3
immunoglobulin kappa variable 2-109
chr9_-_85209162 1.45 ENSMUST00000034802.15
terminal nucleotidyltransferase 5A
chr1_-_143879738 1.43 ENSMUST00000153527.3
regulator of G-protein signaling 2
chr19_+_6450641 1.42 ENSMUST00000113467.2
RAS, guanyl releasing protein 2
chr5_+_21748523 1.41 ENSMUST00000035651.6
leucine rich repeat containing 17
chr13_+_22227359 1.37 ENSMUST00000110452.2
H2B clustered histone 11
chr6_-_69282389 1.37 ENSMUST00000103350.3
immunoglobulin kappa variable 4-68
chr9_-_85209340 1.36 ENSMUST00000187711.2
terminal nucleotidyltransferase 5A
chr3_+_96177010 1.36 ENSMUST00000051089.4
ENSMUST00000177113.2
predicted gene 42743
H2B clustered histone 18
chr3_-_97134680 1.33 ENSMUST00000046521.14
B cell CLL/lymphoma 9
chr12_-_113802603 1.32 ENSMUST00000103458.3
ENSMUST00000193652.2
immunoglobulin heavy variable 5-16
chr14_+_79753055 1.31 ENSMUST00000110835.3
ENSMUST00000227192.2
E74-like factor 1
chr12_-_114117264 1.31 ENSMUST00000103461.5
immunoglobulin heavy variable 7-3
chr12_-_115258124 1.30 ENSMUST00000192591.2
immunoglobulin heavy variable 8-8
chr12_-_114621406 1.30 ENSMUST00000192077.2
immunoglobulin heavy variable 1-15
chr12_-_113733922 1.28 ENSMUST00000180013.3
immunoglobulin heavy variable 2-9-1
chr8_+_55407872 1.26 ENSMUST00000033915.9
glycoprotein m6a
chr18_+_36780913 1.25 ENSMUST00000140061.8
multiple ankyrin repeats single KH domain binding protein 3
chr6_+_70348416 1.25 ENSMUST00000103391.4
immunoglobulin kappa variable 6-17
chr8_-_116434517 1.22 ENSMUST00000109104.2
avian musculoaponeurotic fibrosarcoma oncogene homolog
chr6_-_70383976 1.19 ENSMUST00000103393.2
immunoglobulin kappa variable 6-15
chr12_-_113912416 1.13 ENSMUST00000103464.3
immunoglobulin heavy variable 4-1
chr12_-_114672701 1.13 ENSMUST00000103505.3
ENSMUST00000193855.2
immunoglobulin heavy variable V1-19
chr6_-_70318437 1.13 ENSMUST00000196599.2
immunoglobulin kappa variable 8-19
chr17_+_27276262 1.11 ENSMUST00000049308.9
inositol 1,4,5-triphosphate receptor 3
chr4_+_3678108 1.09 ENSMUST00000041377.13
ENSMUST00000103010.4
LYN proto-oncogene, Src family tyrosine kinase
chr12_-_114226570 1.09 ENSMUST00000103479.4
ENSMUST00000195619.2
immunoglobulin heavy variable 3-5
chr6_-_29216276 1.08 ENSMUST00000162215.8
inosine monophosphate dehydrogenase 1
chr6_+_68657317 1.07 ENSMUST00000198735.2
immunoglobulin kappa variable 10-95
chr16_-_4698148 1.06 ENSMUST00000037843.7
UBA-like domain containing 1
chr10_+_119655294 1.06 ENSMUST00000105262.9
ENSMUST00000147454.8
ENSMUST00000138410.8
ENSMUST00000144825.8
ENSMUST00000148954.8
ENSMUST00000144959.8
glutamate receptor interacting protein 1
chr16_+_23043474 1.06 ENSMUST00000023601.14
beta galactoside alpha 2,6 sialyltransferase 1
chr8_+_31640332 1.05 ENSMUST00000209851.2
ENSMUST00000098842.3
ENSMUST00000210129.2
TELO2 interacting protein 2
chr6_-_70149254 1.05 ENSMUST00000197272.2
immunoglobulin kappa chain variable 8-27
chr7_+_24981604 1.04 ENSMUST00000163320.8
ENSMUST00000005578.13
capicua transcriptional repressor
chr2_+_28083105 1.03 ENSMUST00000100244.10
olfactomedin 1
chr7_-_15781838 1.03 ENSMUST00000210781.2
BRD4 interacting chromatin remodeling complex associated protein
chr9_-_57168777 1.02 ENSMUST00000217657.2
RIKEN cDNA 1700017B05 gene
chr11_+_115272732 1.01 ENSMUST00000053288.6
cerebellar degeneration-related protein 2-like
chr12_-_115172211 1.00 ENSMUST00000103526.3
immunoglobulin heavy variable 1-55
chr6_-_70364222 0.99 ENSMUST00000103392.3
ENSMUST00000195945.2
immunoglobulin kappa variable 8-16
chr5_-_115791032 0.99 ENSMUST00000121746.8
ENSMUST00000118576.8
BICD family like cargo adaptor 1
chr13_+_21906214 0.98 ENSMUST00000224651.2
H2B clustered histone 14
chr7_-_28071919 0.98 ENSMUST00000119990.8
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr6_-_70194405 0.98 ENSMUST00000103384.2
immunoglobulin kappa chain variable 8-24
chr7_-_37472979 0.97 ENSMUST00000176534.8
zinc finger protein 536
chr9_+_75093177 0.97 ENSMUST00000129281.8
ENSMUST00000148144.8
ENSMUST00000130384.2
myosin VA
chr8_-_116433733 0.96 ENSMUST00000069009.7
avian musculoaponeurotic fibrosarcoma oncogene homolog
chr10_+_128542120 0.96 ENSMUST00000054125.9
premelanosome protein
chr7_-_125799644 0.95 ENSMUST00000168189.8
exportin 6
chr5_+_75316552 0.94 ENSMUST00000168162.5
platelet derived growth factor receptor, alpha polypeptide
chr3_+_75982890 0.94 ENSMUST00000160261.8
follistatin-like 5
chr8_-_65489834 0.93 ENSMUST00000142822.4
apelin receptor early endogenous ligand
chr13_+_23930717 0.93 ENSMUST00000099703.5
H2B clustered histone 3
chr13_+_5911481 0.92 ENSMUST00000000080.8
Kruppel-like factor 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 14.0 GO:1903288 positive regulation of potassium ion import(GO:1903288)
2.2 8.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
1.7 6.9 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
1.3 4.0 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
1.3 5.1 GO:0061215 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
1.2 6.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
1.2 16.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
1.2 9.4 GO:0002432 granuloma formation(GO:0002432)
1.1 4.3 GO:0021993 initiation of neural tube closure(GO:0021993)
1.0 4.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
1.0 4.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.9 7.4 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.9 9.0 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.8 3.2 GO:0045659 negative regulation of neutrophil differentiation(GO:0045659)
0.7 3.5 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.7 4.6 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.6 4.2 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.6 2.9 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.5 2.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.5 1.6 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.5 1.6 GO:0070948 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
0.5 5.1 GO:0032264 IMP salvage(GO:0032264)
0.5 3.4 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.4 1.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.4 1.3 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.4 3.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.4 2.6 GO:0007412 axon target recognition(GO:0007412)
0.4 0.8 GO:0032741 positive regulation of interleukin-18 production(GO:0032741)
0.4 1.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.4 3.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.3 48.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.3 5.7 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 0.9 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3 2.7 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.3 16.4 GO:0006284 base-excision repair(GO:0006284)
0.3 1.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 0.5 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257)
0.3 0.8 GO:2000040 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.3 4.8 GO:0070995 NADPH oxidation(GO:0070995)
0.2 2.0 GO:0048539 bone marrow development(GO:0048539)
0.2 3.9 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2 2.0 GO:0006265 DNA topological change(GO:0006265)
0.2 0.9 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.2 2.4 GO:1902033 regulation of hematopoietic stem cell proliferation(GO:1902033)
0.2 1.1 GO:1990743 protein sialylation(GO:1990743)
0.2 4.8 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.2 3.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.0 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.2 0.8 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.2 1.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.2 1.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 3.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 0.7 GO:0006649 phospholipid transfer to membrane(GO:0006649)
0.2 7.4 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.2 0.8 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 0.8 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 1.8 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 2.0 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 1.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.6 GO:1902896 terminal web assembly(GO:1902896)
0.1 1.5 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 4.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.0 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.7 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.2 GO:2000471 regulation of eosinophil degranulation(GO:0043309) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.1 2.7 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 8.3 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 1.9 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.9 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031) adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.1 2.9 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.5 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 0.7 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.1 22.6 GO:0002377 immunoglobulin production(GO:0002377)
0.1 6.5 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 1.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.6 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.1 0.2 GO:0071336 hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336)
0.1 0.4 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 4.1 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 0.5 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 1.0 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 0.7 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.4 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 4.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.7 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.1 0.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 1.3 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 1.3 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 3.1 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 3.1 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 1.5 GO:0030225 macrophage differentiation(GO:0030225)
0.0 3.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.7 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.7 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 2.9 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 2.3 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.0 0.2 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.0 1.6 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 2.2 GO:0045576 mast cell activation(GO:0045576)
0.0 0.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.5 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0060762 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) germline stem cell asymmetric division(GO:0098728)
0.0 1.6 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 1.7 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 4.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 2.9 GO:0007338 single fertilization(GO:0007338)
0.0 2.3 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 1.7 GO:0001824 blastocyst development(GO:0001824)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.9 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 2.7 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.3 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.0 0.5 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 16.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.6 4.8 GO:1990031 pinceau fiber(GO:1990031)
1.5 4.4 GO:0005588 collagen type V trimer(GO:0005588)
1.4 14.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.2 3.5 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.9 9.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.9 4.6 GO:0071953 elastic fiber(GO:0071953)
0.8 7.6 GO:0019815 B cell receptor complex(GO:0019815)
0.4 48.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.4 4.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.4 3.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 1.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 2.0 GO:0031298 replication fork protection complex(GO:0031298)
0.3 1.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.3 7.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 1.0 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.2 2.0 GO:0042382 paraspeckles(GO:0042382)
0.2 6.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 4.2 GO:0042627 chylomicron(GO:0042627)
0.1 0.8 GO:0036019 endolysosome(GO:0036019)
0.1 4.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.6 GO:0031251 PAN complex(GO:0031251)
0.1 1.0 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 1.6 GO:0000243 commitment complex(GO:0000243)
0.1 2.0 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.8 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 0.4 GO:0035976 AP1 complex(GO:0035976)
0.1 4.7 GO:0031519 PcG protein complex(GO:0031519)
0.1 1.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.6 GO:0031143 pseudopodium(GO:0031143)
0.1 1.6 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.9 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.6 GO:1990357 terminal web(GO:1990357)
0.1 1.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 2.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 19.5 GO:0016607 nuclear speck(GO:0016607)
0.0 5.3 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 5.6 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0043512 inhibin A complex(GO:0043512)
0.0 2.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 6.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 2.0 GO:0005902 microvillus(GO:0005902)
0.0 4.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.7 GO:0031526 brush border membrane(GO:0031526)
0.0 1.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 4.6 GO:0001726 ruffle(GO:0001726)
0.0 3.4 GO:0030027 lamellipodium(GO:0030027)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 3.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 5.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 21.0 GO:0005615 extracellular space(GO:0005615)
0.0 2.1 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 16.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.7 6.9 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
1.2 14.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.0 4.8 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.9 2.7 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.7 7.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.7 2.8 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.7 3.5 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.7 2.0 GO:0097100 supercoiled DNA binding(GO:0097100)
0.7 2.6 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.6 4.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.6 12.3 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.5 5.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 3.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.4 4.1 GO:0045545 syndecan binding(GO:0045545)
0.4 1.6 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.4 1.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.4 48.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.4 5.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 0.9 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.3 0.8 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.3 1.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.3 1.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.3 1.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 2.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.2 2.7 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 1.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 3.5 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.7 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.2 4.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 0.8 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 4.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 2.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 1.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 0.8 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 3.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 2.0 GO:0030274 LIM domain binding(GO:0030274)
0.1 3.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.6 GO:1990188 euchromatin binding(GO:1990188)
0.1 1.0 GO:0034452 dynactin binding(GO:0034452)
0.1 2.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 6.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 2.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.9 GO:0046790 virion binding(GO:0046790)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.8 GO:0035497 cAMP response element binding(GO:0035497)
0.1 4.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.8 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 6.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 18.1 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 5.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.2 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.1 3.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.8 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 1.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.1 2.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 3.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 1.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 4.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.5 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 2.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.9 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 1.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 6.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.9 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 4.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 3.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 2.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.4 15.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 3.5 PID IL5 PATHWAY IL5-mediated signaling events
0.2 21.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 10.3 PID BCR 5PATHWAY BCR signaling pathway
0.1 8.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 7.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 4.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 9.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 5.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 4.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 1.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 1.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 1.6 ST GA12 PATHWAY G alpha 12 Pathway
0.1 2.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 3.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 6.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 4.8 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 3.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 16.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3 13.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.3 13.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 3.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 12.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 8.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 5.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 3.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 7.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 4.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 9.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 3.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 2.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 4.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 6.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.9 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.8 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 13.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 4.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 3.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 3.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport