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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Rara

Z-value: 0.70

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Transcription factors associated with Rara

Gene Symbol Gene ID Gene Info
Rara
ENSMUSG00000037992.17 Rara

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Raramm39_v1_chr11_+_98828495_98828559-0.124.8e-01Click!

Activity profile of Rara motif

Sorted Z-values of Rara motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Rara

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_-_5865124 3.10 ENSMUST00000109823.9
ENSMUST00000109822.8
Gck
glucokinase
chr19_+_37686240 2.56 ENSMUST00000025946.7
Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
chr8_-_72966663 2.30 ENSMUST00000098630.5
Cib3
calcium and integrin binding family member 3
chr4_-_46991842 2.01 ENSMUST00000107749.4
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr19_-_7780025 1.86 ENSMUST00000065634.8
Slc22a26
solute carrier family 22 (organic cation transporter), member 26
chr19_-_7779943 1.67 ENSMUST00000120522.8
Slc22a26
solute carrier family 22 (organic cation transporter), member 26
chrX_-_74918122 1.44 ENSMUST00000033547.14
Pls3
plastin 3 (T-isoform)
chr2_+_32498997 1.11 ENSMUST00000143625.2
ENSMUST00000128811.2
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr6_-_124519240 1.00 ENSMUST00000159463.8
ENSMUST00000162844.2
ENSMUST00000160505.8
ENSMUST00000162443.8
C1s1
complement component 1, s subcomponent 1
chr3_+_122305819 0.94 ENSMUST00000199344.2
Bcar3
breast cancer anti-estrogen resistance 3
chr5_-_105387395 0.90 ENSMUST00000065588.7
Gbp10
guanylate-binding protein 10
chr7_-_44320244 0.90 ENSMUST00000048102.15
Myh14
myosin, heavy polypeptide 14
chr12_+_108859557 0.90 ENSMUST00000221377.2
Wdr25
WD repeat domain 25
chr10_+_4561974 0.88 ENSMUST00000105590.8
ENSMUST00000067086.14
Esr1
estrogen receptor 1 (alpha)
chr11_+_98851238 0.82 ENSMUST00000107473.3
Rara
retinoic acid receptor, alpha
chr1_-_14374794 0.66 ENSMUST00000190337.7
Eya1
EYA transcriptional coactivator and phosphatase 1
chr1_+_157286124 0.64 ENSMUST00000193791.6
ENSMUST00000046743.11
ENSMUST00000119891.7
Cryzl2
crystallin zeta like 2
chr1_-_14374842 0.64 ENSMUST00000188857.7
ENSMUST00000185453.7
Eya1
EYA transcriptional coactivator and phosphatase 1
chr3_+_79792238 0.49 ENSMUST00000135021.2
Gask1b
golgi associated kinase 1B
chr5_-_113285852 0.49 ENSMUST00000212276.2
2900026A02Rik
RIKEN cDNA 2900026A02 gene
chr16_-_94657531 0.48 ENSMUST00000232562.2
ENSMUST00000165538.3
Kcnj6
potassium inwardly-rectifying channel, subfamily J, member 6
chr5_-_114411851 0.47 ENSMUST00000044790.12
Foxn4
forkhead box N4
chr2_+_120807498 0.46 ENSMUST00000067582.14
Tmem62
transmembrane protein 62
chr2_+_32498716 0.44 ENSMUST00000129165.2
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr5_+_88073483 0.43 ENSMUST00000113271.3
Csn3
casein kappa
chr11_-_5211558 0.38 ENSMUST00000020662.15
Kremen1
kringle containing transmembrane protein 1
chr7_+_16884194 0.37 ENSMUST00000108491.8
Ceacam3
carcinoembryonic antigen-related cell adhesion molecule 3
chr5_+_114991722 0.37 ENSMUST00000031547.12
4930519G04Rik
RIKEN cDNA 4930519G04 gene
chr3_-_36529753 0.37 ENSMUST00000199478.2
Anxa5
annexin A5
chr7_-_18350423 0.36 ENSMUST00000057810.7
Psg23
pregnancy-specific glycoprotein 23
chr4_-_123458465 0.35 ENSMUST00000238731.2
Macf1
microtubule-actin crosslinking factor 1
chr12_-_54909568 0.34 ENSMUST00000078124.8
Cfl2
cofilin 2, muscle
chr5_+_88073438 0.33 ENSMUST00000001667.13
ENSMUST00000113267.8
Csn3
casein kappa
chr4_+_48045143 0.33 ENSMUST00000030025.10
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr2_+_169475436 0.32 ENSMUST00000109157.2
Tshz2
teashirt zinc finger family member 2
chr4_+_150938376 0.31 ENSMUST00000073600.9
Errfi1
ERBB receptor feedback inhibitor 1
chr4_-_152402915 0.30 ENSMUST00000170820.3
ENSMUST00000076183.12
Rnf207
ring finger protein 207
chr8_+_106877025 0.29 ENSMUST00000212963.2
ENSMUST00000034377.8
Pla2g15
phospholipase A2, group XV
chr1_-_172034251 0.28 ENSMUST00000155109.2
Pea15a
phosphoprotein enriched in astrocytes 15A
chr10_-_8638215 0.28 ENSMUST00000212553.2
Sash1
SAM and SH3 domain containing 1
chr3_-_88194517 0.28 ENSMUST00000165196.8
Gm38392
predicted gene, 38392
chr5_+_14075281 0.28 ENSMUST00000073957.8
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr6_-_13677928 0.27 ENSMUST00000203078.2
ENSMUST00000045235.8
Bmt2
base methyltransferase of 25S rRNA 2
chr3_-_87965757 0.26 ENSMUST00000029708.8
Naxe
NAD(P)HX epimerase
chrX_-_104918911 0.25 ENSMUST00000200471.2
Atrx
ATRX, chromatin remodeler
chr9_-_56325344 0.24 ENSMUST00000061552.15
Peak1
pseudopodium-enriched atypical kinase 1
chr17_-_67939702 0.24 ENSMUST00000097290.4
Lrrc30
leucine rich repeat containing 30
chr2_+_173561208 0.23 ENSMUST00000073081.6
1700010B08Rik
RIKEN cDNA 1700010B08 gene
chr7_-_30156826 0.23 ENSMUST00000045817.14
Kirrel2
kirre like nephrin family adhesion molecule 2
chr2_+_181007177 0.23 ENSMUST00000108807.9
Zgpat
zinc finger, CCCH-type with G patch domain
chr3_+_121220146 0.23 ENSMUST00000029773.13
Cnn3
calponin 3, acidic
chr6_+_41107047 0.23 ENSMUST00000103271.2
Trbv13-3
T cell receptor beta, variable 13-3
chr9_-_56325307 0.23 ENSMUST00000186735.2
Peak1
pseudopodium-enriched atypical kinase 1
chr4_-_128503774 0.23 ENSMUST00000141040.2
ENSMUST00000147876.2
ENSMUST00000097877.9
Zscan20
zinc finger and SCAN domains 20
chr14_+_58308004 0.21 ENSMUST00000165526.9
Fgf9
fibroblast growth factor 9
chr2_-_5017526 0.21 ENSMUST00000027980.8
Mcm10
minichromosome maintenance 10 replication initiation factor
chr11_+_49184124 0.19 ENSMUST00000189851.3
Olfr1392
olfactory receptor 1392
chr6_+_114108190 0.18 ENSMUST00000032451.9
Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chrX_-_104919201 0.18 ENSMUST00000198209.2
Atrx
ATRX, chromatin remodeler
chr13_+_83720484 0.17 ENSMUST00000196207.5
Mef2c
myocyte enhancer factor 2C
chr17_-_56440817 0.17 ENSMUST00000167545.3
Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr4_+_119590971 0.17 ENSMUST00000084306.5
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr3_+_79791798 0.16 ENSMUST00000118853.8
ENSMUST00000145992.2
Gask1b
golgi associated kinase 1B
chr14_-_30075424 0.16 ENSMUST00000224198.3
ENSMUST00000238675.2
ENSMUST00000112249.10
ENSMUST00000224785.3
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr8_+_91681550 0.16 ENSMUST00000210947.2
Chd9
chromodomain helicase DNA binding protein 9
chr1_+_93096316 0.15 ENSMUST00000138595.3
Crocc2
ciliary rootlet coiled-coil, rootletin family member 2
chr2_-_90900525 0.14 ENSMUST00000153367.2
ENSMUST00000079976.10
Slc39a13
solute carrier family 39 (metal ion transporter), member 13
chr14_+_5894220 0.13 ENSMUST00000063750.8
Rarb
retinoic acid receptor, beta
chr13_+_83720457 0.13 ENSMUST00000196730.5
Mef2c
myocyte enhancer factor 2C
chr12_-_108859123 0.13 ENSMUST00000161154.2
ENSMUST00000161410.8
Wars
tryptophanyl-tRNA synthetase
chr3_+_93376058 0.13 ENSMUST00000029516.3
Tchhl1
trichohyalin-like 1
chrX_-_58612709 0.12 ENSMUST00000124402.2
Fgf13
fibroblast growth factor 13
chr14_-_75185281 0.12 ENSMUST00000088970.7
ENSMUST00000228252.2
Lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr14_-_70445086 0.12 ENSMUST00000022682.6
Sorbs3
sorbin and SH3 domain containing 3
chr3_+_89136353 0.11 ENSMUST00000041142.4
Muc1
mucin 1, transmembrane
chr3_+_96011810 0.11 ENSMUST00000132980.8
ENSMUST00000138206.8
ENSMUST00000090785.9
ENSMUST00000035519.12
Otud7b
OTU domain containing 7B
chr1_+_131678223 0.11 ENSMUST00000147800.2
Slc26a9
solute carrier family 26, member 9
chr7_+_15280907 0.11 ENSMUST00000067288.15
Obox1
oocyte specific homeobox 1
chr11_-_50844572 0.10 ENSMUST00000162420.2
ENSMUST00000051159.3
Prop1
paired like homeodomain factor 1
chr7_-_141009346 0.10 ENSMUST00000124444.2
Cend1
cell cycle exit and neuronal differentiation 1
chr19_-_12209960 0.10 ENSMUST00000207710.3
Olfr1432
olfactory receptor 1432
chrX_+_159865500 0.09 ENSMUST00000238603.2
Scml2
Scm polycomb group protein like 2
chr13_-_65200204 0.09 ENSMUST00000222769.2
Prss47
protease, serine 47
chr4_+_32238950 0.09 ENSMUST00000037416.13
Bach2
BTB and CNC homology, basic leucine zipper transcription factor 2
chr14_-_70043079 0.09 ENSMUST00000022665.4
Rhobtb2
Rho-related BTB domain containing 2
chr7_-_141009264 0.08 ENSMUST00000164387.2
ENSMUST00000137488.2
ENSMUST00000084436.10
Cend1
cell cycle exit and neuronal differentiation 1
chr8_-_120505104 0.08 ENSMUST00000212534.2
ENSMUST00000049156.7
Meak7
MTOR associated protein , eak-7 homolog
chr6_-_54949587 0.08 ENSMUST00000060655.15
Nod1
nucleotide-binding oligomerization domain containing 1
chr13_-_65200574 0.08 ENSMUST00000203968.3
Prss47
protease, serine 47
chr7_+_4925781 0.07 ENSMUST00000207527.2
ENSMUST00000207687.2
ENSMUST00000208754.2
Nat14
N-acetyltransferase 14
chr1_-_172034354 0.07 ENSMUST00000013842.12
ENSMUST00000111247.8
Pea15a
phosphoprotein enriched in astrocytes 15A
chr9_-_96513529 0.06 ENSMUST00000034984.8
Rasa2
RAS p21 protein activator 2
chr7_-_18390645 0.06 ENSMUST00000094793.12
ENSMUST00000182128.2
Psg21
pregnancy-specific glycoprotein 21
chr3_+_79252668 0.06 ENSMUST00000164216.6
ENSMUST00000199658.2
Gm17359
predicted gene, 17359
chr7_+_120234399 0.06 ENSMUST00000033176.7
ENSMUST00000208400.2
Uqcrc2
ubiquinol cytochrome c reductase core protein 2
chr6_+_67873135 0.05 ENSMUST00000103310.3
Igkv14-126
immunoglobulin kappa variable 14-126
chr5_-_137623331 0.05 ENSMUST00000031732.14
Fbxo24
F-box protein 24
chr7_+_17447163 0.04 ENSMUST00000081907.8
Ceacam5
carcinoembryonic antigen-related cell adhesion molecule 5
chr13_+_95012107 0.04 ENSMUST00000022195.13
Otp
orthopedia homeobox
chr5_+_53424471 0.03 ENSMUST00000147148.5
Smim20
small integral membrane protein 20
chr18_-_39652468 0.03 ENSMUST00000237944.2
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr13_+_49574694 0.03 ENSMUST00000220447.2
Ippk
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr4_+_42969934 0.03 ENSMUST00000190902.2
ENSMUST00000030163.12
1700022I11Rik
RIKEN cDNA 1700022I11 gene
chr15_-_102274781 0.02 ENSMUST00000078508.7
Sp7
Sp7 transcription factor 7
chr11_+_87457544 0.02 ENSMUST00000060360.7
Septin4
septin 4
chr1_-_163231196 0.01 ENSMUST00000045138.6
Gorab
golgin, RAB6-interacting
chr7_+_45522551 0.01 ENSMUST00000211234.2
Kdelr1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr3_-_94922525 0.00 ENSMUST00000128438.2
ENSMUST00000149747.2
ENSMUST00000019482.8
Zfp687
zinc finger protein 687

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.4 2.6 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.3 0.8 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 3.5 GO:0015747 urate transport(GO:0015747)
0.1 0.9 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 1.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.3 GO:1903116 positive regulation of actin filament-based movement(GO:1903116)
0.1 0.3 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.3 GO:1900623 positive regulation of mast cell cytokine production(GO:0032765) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:1901582 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.1 0.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.4 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.3 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.3 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0021941 radial glia guided migration of cerebellar granule cell(GO:0021933) negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
0.0 2.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.3 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.9 GO:0071625 vocalization behavior(GO:0071625)
0.0 1.1 GO:0001562 response to protozoan(GO:0001562)
0.0 0.1 GO:0060126 hypophysis morphogenesis(GO:0048850) somatotropin secreting cell differentiation(GO:0060126)
0.0 0.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.5 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.8 GO:0007595 lactation(GO:0007595)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 3.0 GO:0045180 basal cortex(GO:0045180)
0.1 0.9 GO:0097513 myosin II filament(GO:0097513)
0.1 0.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.4 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 1.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 2.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 3.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.3 0.9 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 3.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 1.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.2 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.0 0.3 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 3.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation