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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Rarb

Z-value: 0.67

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Transcription factors associated with Rarb

Gene Symbol Gene ID Gene Info
Rarb
ENSMUSG00000017491.10 Rarb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rarbmm39_v1_chr14_+_5894220_58942540.182.8e-01Click!

Activity profile of Rarb motif

Sorted Z-values of Rarb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Rarb

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_-_85797946 2.77 ENSMUST00000032074.5
Nat8f5
N-acetyltransferase 8 (GCN5-related) family member 5
chr5_-_87074380 1.68 ENSMUST00000031183.3
Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
chr12_+_8027767 1.43 ENSMUST00000037520.14
Apob
apolipoprotein B
chr12_+_8027640 1.39 ENSMUST00000171271.8
ENSMUST00000037811.13
Apob
apolipoprotein B
chr5_-_87288177 1.24 ENSMUST00000067790.7
Ugt2b5
UDP glucuronosyltransferase 2 family, polypeptide B5
chr5_-_87054796 1.02 ENSMUST00000031181.16
ENSMUST00000113333.2
Ugt2b34
UDP glucuronosyltransferase 2 family, polypeptide B34
chr7_-_115630282 0.80 ENSMUST00000206034.2
ENSMUST00000106612.8
Sox6
SRY (sex determining region Y)-box 6
chr1_+_4878046 0.78 ENSMUST00000027036.11
ENSMUST00000150971.8
ENSMUST00000119612.9
ENSMUST00000137887.8
ENSMUST00000115529.8
Lypla1
lysophospholipase 1
chr5_-_33375509 0.61 ENSMUST00000201475.2
Spon2
spondin 2, extracellular matrix protein
chr19_+_28967875 0.56 ENSMUST00000224599.2
ENSMUST00000050148.5
Cdc37l1
cell division cycle 37-like 1
chr1_+_191553556 0.49 ENSMUST00000027931.8
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr6_+_108771840 0.45 ENSMUST00000204483.2
Arl8b
ADP-ribosylation factor-like 8B
chr10_-_92558219 0.45 ENSMUST00000020163.7
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr17_+_12803019 0.40 ENSMUST00000046959.9
ENSMUST00000233066.2
Slc22a2
solute carrier family 22 (organic cation transporter), member 2
chr10_+_67021509 0.39 ENSMUST00000173689.8
Jmjd1c
jumonji domain containing 1C
chr2_+_3771709 0.35 ENSMUST00000177037.2
Fam107b
family with sequence similarity 107, member B
chr6_-_85797917 0.35 ENSMUST00000174143.2
Nat8f6
N-acetyltransferase 8 (GCN5-related) family member 6
chr7_+_35148461 0.23 ENSMUST00000118969.8
Slc7a9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr2_+_30171055 0.23 ENSMUST00000143119.3
Gm28038
predicted gene, 28038
chr10_-_126737185 0.22 ENSMUST00000168520.3
ENSMUST00000026504.13
Atp23
ATP23 metallopeptidase and ATP synthase assembly factor homolog
chr7_+_35148579 0.19 ENSMUST00000032703.10
Slc7a9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr7_+_35148188 0.19 ENSMUST00000118383.8
Slc7a9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr11_+_105069591 0.13 ENSMUST00000106939.9
Tlk2
tousled-like kinase 2 (Arabidopsis)
chr19_+_44980565 0.12 ENSMUST00000179305.2
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr7_+_45267024 0.09 ENSMUST00000008605.6
ENSMUST00000209379.2
Fut1
fucosyltransferase 1
chr15_-_98560739 0.08 ENSMUST00000162384.2
ENSMUST00000003450.15
Ddx23
DEAD box helicase 23
chr7_+_127503251 0.05 ENSMUST00000071056.14
Bckdk
branched chain ketoacid dehydrogenase kinase
chr2_-_163259012 0.04 ENSMUST00000127038.2
Oser1
oxidative stress responsive serine rich 1
chr4_-_118314647 0.03 ENSMUST00000106375.2
ENSMUST00000168404.9
ENSMUST00000006556.11
Mpl
myeloproliferative leukemia virus oncogene
chr19_-_8763609 0.02 ENSMUST00000177216.8
ENSMUST00000176610.9
ENSMUST00000177056.8
Taf6l
TATA-box binding protein associated factor 6 like
chr11_+_76795346 0.02 ENSMUST00000072633.4
Tmigd1
transmembrane and immunoglobulin domain containing 1
chr11_-_71092124 0.02 ENSMUST00000108514.10
Nlrp1b
NLR family, pyrin domain containing 1B
chr19_-_8763771 0.01 ENSMUST00000176496.8
Taf6l
TATA-box binding protein associated factor 6 like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0018879 biphenyl metabolic process(GO:0018879)
0.2 2.8 GO:0006642 triglyceride mobilization(GO:0006642)
0.2 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.6 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.8 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.5 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.8 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 2.8 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.4 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.0 0.5 GO:0071539 protein localization to centrosome(GO:0071539)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0034359 mature chylomicron(GO:0034359)
0.1 0.5 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 GO:0035473 lipase binding(GO:0035473)
0.2 0.6 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.4 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.1 3.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 2.8 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.5 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions