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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Rest

Z-value: 2.12

Motif logo

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Transcription factors associated with Rest

Gene Symbol Gene ID Gene Info
Rest
ENSMUSG00000029249.16 Rest

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Restmm39_v1_chr5_+_77413282_77413396-0.729.6e-07Click!

Activity profile of Rest motif

Sorted Z-values of Rest motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Rest

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_+_102284229 4.92 ENSMUST00000107105.9
ENSMUST00000107102.8
ENSMUST00000107103.8
ENSMUST00000006750.8
Rundc3a
RUN domain containing 3A
chr13_-_54897425 4.62 ENSMUST00000099506.2
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr2_+_152873772 4.58 ENSMUST00000037235.7
Xkr7
X-linked Kx blood group related 7
chr15_-_76406602 4.47 ENSMUST00000096365.5
Scrt1
scratch family zinc finger 1
chr13_-_54897660 4.03 ENSMUST00000135343.2
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr19_+_42244143 3.64 ENSMUST00000087123.6
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr2_+_155617251 3.36 ENSMUST00000029141.6
Mmp24
matrix metallopeptidase 24
chr1_-_175319842 3.28 ENSMUST00000195324.6
ENSMUST00000192227.6
ENSMUST00000194555.6
Rgs7
regulator of G protein signaling 7
chr2_-_179746227 3.12 ENSMUST00000056480.10
Hrh3
histamine receptor H3
chr17_-_25459086 2.96 ENSMUST00000038973.7
ENSMUST00000115154.11
Gnptg
N-acetylglucosamine-1-phosphotransferase, gamma subunit
chr15_-_76406102 2.82 ENSMUST00000164703.2
Scrt1
scratch family zinc finger 1
chrX_+_7504913 2.41 ENSMUST00000128890.2
Syp
synaptophysin
chr7_-_27095964 2.33 ENSMUST00000108363.8
Sptbn4
spectrin beta, non-erythrocytic 4
chr9_-_21996693 2.20 ENSMUST00000179422.8
ENSMUST00000098937.10
ENSMUST00000177967.2
ENSMUST00000180180.8
Ecsit
ECSIT signalling integrator
chr9_+_59485475 2.13 ENSMUST00000118549.8
ENSMUST00000034840.10
Celf6
CUGBP, Elav-like family member 6
chr11_+_77821626 2.07 ENSMUST00000093995.10
ENSMUST00000000646.14
Sez6
seizure related gene 6
chr12_+_102915709 1.94 ENSMUST00000179002.8
Unc79
unc-79 homolog
chr12_+_113104085 1.92 ENSMUST00000200380.5
Crip2
cysteine rich protein 2
chr1_+_34618738 1.90 ENSMUST00000052670.11
Amer3
APC membrane recruitment 3
chr11_-_3724706 1.88 ENSMUST00000155197.2
Osbp2
oxysterol binding protein 2
chr7_-_81143631 1.81 ENSMUST00000082090.15
Ap3b2
adaptor-related protein complex 3, beta 2 subunit
chr9_+_40785277 1.81 ENSMUST00000067375.5
Bsx
brain specific homeobox
chr5_+_137059522 1.80 ENSMUST00000187382.2
Vgf
VGF nerve growth factor inducible
chr5_+_137059127 1.77 ENSMUST00000041543.9
ENSMUST00000186451.2
Vgf
VGF nerve growth factor inducible
chr7_-_81143412 1.74 ENSMUST00000238438.2
ENSMUST00000238711.2
Ap3b2
adaptor-related protein complex 3, beta 2 subunit
chr12_-_84745388 1.73 ENSMUST00000221905.2
ENSMUST00000222422.2
ENSMUST00000095550.4
Syndig1l
synapse differentiation inducing 1 like
chr12_-_70394272 1.67 ENSMUST00000221370.2
Trim9
tripartite motif-containing 9
chr8_+_56393488 1.63 ENSMUST00000000275.10
Glra3
glycine receptor, alpha 3 subunit
chr12_+_113103817 1.63 ENSMUST00000084882.9
Crip2
cysteine rich protein 2
chr2_+_164810139 1.63 ENSMUST00000202479.4
Slc12a5
solute carrier family 12, member 5
chr14_-_62718581 1.63 ENSMUST00000186010.8
Gm4131
predicted gene 4131
chr2_-_26098293 1.62 ENSMUST00000054099.16
Lhx3
LIM homeobox protein 3
chr3_+_94385661 1.62 ENSMUST00000200342.5
Celf3
CUGBP, Elav-like family member 3
chr11_+_80367839 1.61 ENSMUST00000053413.12
ENSMUST00000147694.2
Cdk5r1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr4_-_129015027 1.57 ENSMUST00000030572.10
Hpca
hippocalcin
chr19_+_22116392 1.57 ENSMUST00000237357.2
ENSMUST00000237820.2
ENSMUST00000236312.2
ENSMUST00000074770.13
ENSMUST00000087576.12
Trpm3
transient receptor potential cation channel, subfamily M, member 3
chr7_+_63094489 1.56 ENSMUST00000058476.14
Otud7a
OTU domain containing 7A
chr12_-_70394074 1.55 ENSMUST00000223160.2
ENSMUST00000222316.2
ENSMUST00000167755.3
ENSMUST00000110520.10
ENSMUST00000110522.10
ENSMUST00000221041.2
ENSMUST00000222603.3
Trim9
tripartite motif-containing 9
chr4_+_152243324 1.53 ENSMUST00000030782.2
Hes2
hes family bHLH transcription factor 2
chr6_-_121450547 1.52 ENSMUST00000046373.8
ENSMUST00000151397.3
Iqsec3
IQ motif and Sec7 domain 3
chr19_+_5088854 1.47 ENSMUST00000053705.8
ENSMUST00000235776.2
B4gat1
beta-1,4-glucuronyltransferase 1
chr6_+_8948608 1.46 ENSMUST00000160300.2
Nxph1
neurexophilin 1
chr11_-_55498559 1.46 ENSMUST00000108853.8
ENSMUST00000075603.5
Glra1
glycine receptor, alpha 1 subunit
chrX_-_72913410 1.46 ENSMUST00000066576.12
ENSMUST00000114430.8
L1cam
L1 cell adhesion molecule
chr5_+_28047147 1.41 ENSMUST00000036227.7
Htr5a
5-hydroxytryptamine (serotonin) receptor 5A
chr7_+_98089623 1.41 ENSMUST00000206435.2
Gucy2d
guanylate cyclase 2d
chr17_+_28794615 1.37 ENSMUST00000232862.2
ENSMUST00000080780.8
Lhfpl5
lipoma HMGIC fusion partner-like 5
chr9_+_40180726 1.36 ENSMUST00000171835.9
Scn3b
sodium channel, voltage-gated, type III, beta
chr17_+_28794727 1.34 ENSMUST00000232974.2
Lhfpl5
lipoma HMGIC fusion partner-like 5
chr7_+_49559859 1.29 ENSMUST00000056442.12
Slc6a5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr9_+_104446682 1.25 ENSMUST00000057742.15
Cpne4
copine IV
chr9_+_104446957 1.25 ENSMUST00000077190.7
Cpne4
copine IV
chr2_-_180956293 1.24 ENSMUST00000103045.4
Stmn3
stathmin-like 3
chr18_-_31580436 1.22 ENSMUST00000025110.5
Syt4
synaptotagmin IV
chr4_-_153567221 1.22 ENSMUST00000105646.3
Ajap1
adherens junction associated protein 1
chr13_-_100037149 1.20 ENSMUST00000022150.8
Cartpt
CART prepropeptide
chr3_-_89671888 1.20 ENSMUST00000200558.5
ENSMUST00000029562.5
Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr3_-_80710097 1.19 ENSMUST00000075316.10
ENSMUST00000107745.8
Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr17_+_25459138 1.19 ENSMUST00000063574.7
Tsr3
TSR3 20S rRNA accumulation
chr4_+_101407608 1.17 ENSMUST00000094953.11
ENSMUST00000106933.2
Dnajc6
DnaJ heat shock protein family (Hsp40) member C6
chr3_+_94385602 1.17 ENSMUST00000199884.5
ENSMUST00000198316.5
ENSMUST00000197558.5
Celf3
CUGBP, Elav-like family member 3
chr12_+_119909692 1.15 ENSMUST00000058644.15
Tmem196
transmembrane protein 196
chr17_-_91400499 1.15 ENSMUST00000160844.10
Nrxn1
neurexin I
chrX_-_20787150 1.14 ENSMUST00000081893.7
ENSMUST00000115345.8
Syn1
synapsin I
chr2_+_22512195 1.13 ENSMUST00000028123.4
Gad2
glutamic acid decarboxylase 2
chr17_+_69746321 1.12 ENSMUST00000169935.2
Akain1
A kinase (PRKA) anchor inhibitor 1
chr7_+_27353331 1.11 ENSMUST00000008088.9
Ttc9b
tetratricopeptide repeat domain 9B
chr12_-_112477536 1.11 ENSMUST00000066791.7
Tmem179
transmembrane protein 179
chr4_-_49681954 1.07 ENSMUST00000029991.3
Ppp3r2
protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II)
chr6_-_134864731 1.06 ENSMUST00000203762.4
ENSMUST00000215088.2
ENSMUST00000066107.10
Gpr19
G protein-coupled receptor 19
chr16_-_37205302 1.06 ENSMUST00000114781.8
ENSMUST00000114780.8
Stxbp5l
syntaxin binding protein 5-like
chr2_-_122144125 1.06 ENSMUST00000147788.8
ENSMUST00000154412.2
ENSMUST00000110537.8
ENSMUST00000148417.8
Duoxa1
dual oxidase maturation factor 1
chr17_-_91400142 1.05 ENSMUST00000160800.9
Nrxn1
neurexin I
chr15_-_76606361 1.05 ENSMUST00000049956.5
Lrrc24
leucine rich repeat containing 24
chr16_-_37205277 1.04 ENSMUST00000114787.8
ENSMUST00000114782.8
ENSMUST00000114775.8
Stxbp5l
syntaxin binding protein 5-like
chr13_-_57043550 1.03 ENSMUST00000022023.13
ENSMUST00000174457.9
ENSMUST00000109871.8
Trpc7
transient receptor potential cation channel, subfamily C, member 7
chr7_-_79244677 1.02 ENSMUST00000172788.3
Rhcg
Rhesus blood group-associated C glycoprotein
chr1_-_192717958 0.95 ENSMUST00000016344.9
Syt14
synaptotagmin XIV
chr2_-_27032441 0.93 ENSMUST00000151224.3
Fam163b
family with sequence similarity 163, member B
chr13_-_24175141 0.92 ENSMUST00000021770.8
Scgn
secretagogin, EF-hand calcium binding protein
chr1_-_84673903 0.90 ENSMUST00000049126.13
Dner
delta/notch-like EGF repeat containing
chr11_-_55499014 0.90 ENSMUST00000102716.10
Glra1
glycine receptor, alpha 1 subunit
chr8_-_105036664 0.86 ENSMUST00000160596.8
ENSMUST00000164175.2
Cmtm1
CKLF-like MARVEL transmembrane domain containing 1
chr10_+_6738809 0.85 ENSMUST00000105602.8
ENSMUST00000078634.12
ENSMUST00000000783.13
ENSMUST00000092731.11
ENSMUST00000154906.8
ENSMUST00000105605.8
ENSMUST00000135502.8
ENSMUST00000052751.14
ENSMUST00000105611.8
ENSMUST00000105603.2
ENSMUST00000105604.8
Oprm1
opioid receptor, mu 1
chr1_+_159351337 0.85 ENSMUST00000192069.6
Tnr
tenascin R
chr11_-_35689711 0.84 ENSMUST00000160726.4
Fbll1
fibrillarin-like 1
chr7_+_28455563 0.82 ENSMUST00000178767.3
Ccer2
coiled-coil glutamate-rich protein 2
chr15_-_11038077 0.81 ENSMUST00000058007.7
Rxfp3
relaxin family peptide receptor 3
chr5_-_121147593 0.79 ENSMUST00000079204.9
Rph3a
rabphilin 3A
chr19_+_8906916 0.76 ENSMUST00000096241.6
Eml3
echinoderm microtubule associated protein like 3
chr5_-_31296173 0.75 ENSMUST00000043475.7
ENSMUST00000201184.2
Ucn
urocortin
chr8_-_105036739 0.74 ENSMUST00000159039.2
Cmtm1
CKLF-like MARVEL transmembrane domain containing 1
chr10_+_5589210 0.69 ENSMUST00000019906.6
Vip
vasoactive intestinal polypeptide
chr5_-_121148143 0.68 ENSMUST00000202406.4
ENSMUST00000200792.2
Rph3a
rabphilin 3A
chr1_-_92830604 0.66 ENSMUST00000160548.8
ENSMUST00000112998.2
Ankmy1
ankyrin repeat and MYND domain containing 1
chr8_+_85673616 0.66 ENSMUST00000067472.14
ENSMUST00000109740.9
Rtbdn
retbindin
chr5_+_38417710 0.66 ENSMUST00000119047.8
Tmem128
transmembrane protein 128
chr2_-_37007795 0.65 ENSMUST00000213817.2
ENSMUST00000215927.2
Olfr362
olfactory receptor 362
chr13_-_105191403 0.64 ENSMUST00000063551.7
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr2_-_25209107 0.64 ENSMUST00000114318.10
ENSMUST00000114310.10
ENSMUST00000114308.10
ENSMUST00000114317.10
ENSMUST00000028335.13
ENSMUST00000114314.10
ENSMUST00000114307.8
Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr2_-_25209199 0.64 ENSMUST00000114312.2
Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr1_+_70764874 0.63 ENSMUST00000053922.12
ENSMUST00000161937.2
ENSMUST00000162182.2
Vwc2l
von Willebrand factor C domain-containing protein 2-like
chr10_-_128505096 0.62 ENSMUST00000238610.2
ENSMUST00000238712.2
Ikzf4
IKAROS family zinc finger 4
chr9_-_121620150 0.62 ENSMUST00000215910.2
ENSMUST00000215477.2
ENSMUST00000163981.3
Hhatl
hedgehog acyltransferase-like
chr11_+_76092909 0.60 ENSMUST00000169560.2
Tlcd3a
TLC domain containing 3A
chr5_-_116729870 0.59 ENSMUST00000076124.7
Srrm4
serine/arginine repetitive matrix 4
chr7_-_3619132 0.57 ENSMUST00000039507.15
ENSMUST00000108645.8
ENSMUST00000148012.2
Oscar
osteoclast associated receptor
chr11_+_73244561 0.57 ENSMUST00000108465.4
Olfr20
olfactory receptor 20
chr2_-_28806639 0.54 ENSMUST00000113847.3
Barhl1
BarH like homeobox 1
chr11_+_76092833 0.48 ENSMUST00000094014.10
Tlcd3a
TLC domain containing 3A
chr15_+_101371353 0.48 ENSMUST00000088049.5
Krt86
keratin 86
chr7_-_6489812 0.47 ENSMUST00000086318.5
ENSMUST00000209866.4
Olfr5
olfactory receptor 5
chr2_+_151985467 0.47 ENSMUST00000089112.6
Tcf15
transcription factor 15
chr12_+_31440842 0.45 ENSMUST00000167432.8
Slc26a3
solute carrier family 26, member 3
chr15_+_91083678 0.41 ENSMUST00000190436.7
CN725425
cDNA sequence CN725425
chr9_+_40180497 0.40 ENSMUST00000049941.12
Scn3b
sodium channel, voltage-gated, type III, beta
chr7_+_6459167 0.39 ENSMUST00000214301.3
Olfr1336
olfactory receptor 1336
chr9_+_40180569 0.34 ENSMUST00000176185.8
Scn3b
sodium channel, voltage-gated, type III, beta
chr2_+_132623198 0.34 ENSMUST00000028826.4
Chgb
chromogranin B
chr6_+_113259262 0.31 ENSMUST00000041203.6
Cpne9
copine family member IX
chr16_+_43574389 0.22 ENSMUST00000229953.2
Drd3
dopamine receptor D3
chr19_-_8906686 0.19 ENSMUST00000096242.5
Rom1
rod outer segment membrane protein 1
chr7_+_122270623 0.15 ENSMUST00000182095.2
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr7_+_122270599 0.07 ENSMUST00000182563.2
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr10_-_115423644 0.06 ENSMUST00000020350.15
Lgr5
leucine rich repeat containing G protein coupled receptor 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
1.0 3.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.8 2.4 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.7 2.9 GO:0021586 pons maturation(GO:0021586)
0.6 3.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.5 1.6 GO:0040040 thermosensory behavior(GO:0040040)
0.5 1.6 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.5 5.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.5 1.6 GO:0031283 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.5 1.4 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.4 0.9 GO:0071317 cellular response to isoquinoline alkaloid(GO:0071317)
0.4 1.2 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.4 2.2 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.3 3.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3 1.2 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.3 1.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.3 0.8 GO:0033967 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.3 1.6 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.3 4.9 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.3 1.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 4.3 GO:0043084 penile erection(GO:0043084)
0.2 2.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 1.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.2 0.6 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.2 2.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.2 3.4 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.2 0.8 GO:0048690 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2 0.8 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 1.9 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 3.6 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 1.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 1.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 1.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 1.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.2 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.1 2.7 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) auditory receptor cell stereocilium organization(GO:0060088)
0.1 1.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 1.1 GO:0007320 insemination(GO:0007320)
0.1 2.8 GO:0030575 nuclear body organization(GO:0030575)
0.1 7.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.1 1.8 GO:0060056 mammary gland involution(GO:0060056)
0.1 2.1 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 1.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.1 2.1 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.5 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.9 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.5 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 1.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 1.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 2.1 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 2.2 GO:0051341 regulation of oxidoreductase activity(GO:0051341)
0.0 0.8 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 1.2 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.0 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 2.3 GO:0008091 spectrin(GO:0008091)
0.3 1.3 GO:0044307 dendritic branch(GO:0044307)
0.2 3.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.2 3.6 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.2 0.8 GO:0072534 perineuronal net(GO:0072534)
0.2 0.7 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.2 7.2 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 2.7 GO:0032426 stereocilium tip(GO:0032426)
0.1 1.6 GO:0044327 dendritic spine head(GO:0044327)
0.1 2.5 GO:0044292 dendrite terminus(GO:0044292)
0.1 2.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 2.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 4.0 GO:0097440 apical dendrite(GO:0097440)
0.1 1.2 GO:0031045 dense core granule(GO:0031045)
0.1 3.8 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 2.5 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 3.6 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.8 GO:0043196 varicosity(GO:0043196)
0.0 1.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 1.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 10.7 GO:0016604 nuclear body(GO:0016604)
0.0 3.1 GO:0043209 myelin sheath(GO:0043209)
0.0 3.6 GO:0005938 cell cortex(GO:0005938)
0.0 5.6 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.9 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.7 3.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.6 4.0 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.4 3.1 GO:0004969 histamine receptor activity(GO:0004969)
0.4 1.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.3 0.8 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.3 2.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 0.8 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.2 2.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 1.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 4.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 0.8 GO:0004966 galanin receptor activity(GO:0004966)
0.2 1.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.3 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 2.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 4.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.6 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.5 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 1.4 GO:0051378 serotonin binding(GO:0051378)
0.1 3.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 3.4 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.1 1.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 4.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.8 GO:0046625 sphingolipid binding(GO:0046625)
0.0 1.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 6.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 3.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 3.8 GO:0000149 SNARE binding(GO:0000149)
0.0 8.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.2 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 1.1 GO:0048306 calcium-dependent protein binding(GO:0048306)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 3.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 3.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 4.0 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 5.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 2.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 1.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.9 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 2.2 REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.0 2.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 3.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation