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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Sox18_Sox12

Z-value: 2.11

Motif logo

Transcription factors associated with Sox18_Sox12

Gene Symbol Gene ID Gene Info
ENSMUSG00000046470.6 Sox18
ENSMUSG00000051817.9 Sox12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox12mm39_v1_chr2_-_152239966_152239997-0.901.8e-13Click!
Sox18mm39_v1_chr2_-_181313415_181313438-0.581.8e-04Click!

Activity profile of Sox18_Sox12 motif

Sorted Z-values of Sox18_Sox12 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox18_Sox12

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_+_40078132 12.96 ENSMUST00000068094.13
ENSMUST00000080171.3
cytochrome P450, family 2, subfamily c, polypeptide 50
chr2_+_102489558 9.98 ENSMUST00000111213.8
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_+_102536701 8.53 ENSMUST00000123759.8
ENSMUST00000005220.11
ENSMUST00000111212.8
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr19_-_40062174 7.60 ENSMUST00000048959.5
cytochrome P450, family 2, subfamily c, polypeptide 54
chr4_+_134123631 7.36 ENSMUST00000105869.9
platelet-activating factor acetylhydrolase 2
chr3_-_113371392 7.23 ENSMUST00000067980.12
amylase 1, salivary
chr5_-_87074380 6.91 ENSMUST00000031183.3
UDP glucuronosyltransferase 2 family, polypeptide B1
chr1_-_72251466 6.90 ENSMUST00000048860.9
melanoregulin
chr13_+_4099001 6.82 ENSMUST00000118717.10
aldo-keto reductase family 1, member C14
chr19_-_8382424 6.22 ENSMUST00000064507.12
ENSMUST00000120540.2
ENSMUST00000096269.11
solute carrier family 22, member 30
chr18_-_75094323 6.06 ENSMUST00000066532.5
lipase, endothelial
chr1_-_130589349 5.81 ENSMUST00000027657.14
complement component 4 binding protein
chr7_+_127399776 5.47 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr1_-_130589321 5.13 ENSMUST00000137276.3
complement component 4 binding protein
chr19_-_7779943 4.97 ENSMUST00000120522.8
solute carrier family 22 (organic cation transporter), member 26
chr9_+_74883377 4.95 ENSMUST00000081746.7
family with sequence similarity 214, member A
chr19_-_7780025 4.55 ENSMUST00000065634.8
solute carrier family 22 (organic cation transporter), member 26
chr16_+_22739028 4.20 ENSMUST00000232097.2
fetuin beta
chr19_-_8109346 4.10 ENSMUST00000065651.5
solute carrier family 22, member 28
chr10_-_127843377 3.81 ENSMUST00000219447.2
ENSMUST00000219780.2
ENSMUST00000219707.2
ENSMUST00000219953.2
ENSMUST00000219183.2
hydroxysteroid (17-beta) dehydrogenase 6
chr1_-_140111138 3.79 ENSMUST00000111976.9
ENSMUST00000066859.13
complement component factor h
chr13_-_55574582 3.77 ENSMUST00000170921.2
coagulation factor XII (Hageman factor)
chr6_+_42222841 3.72 ENSMUST00000031897.8
glutathione S-transferase kappa 1
chr1_+_67162176 3.72 ENSMUST00000027144.8
carbamoyl-phosphate synthetase 1
chr13_-_55574596 3.61 ENSMUST00000021948.15
coagulation factor XII (Hageman factor)
chr2_+_121978156 3.60 ENSMUST00000102476.5
beta-2 microglobulin
chr14_-_52151537 3.59 ENSMUST00000227402.2
ENSMUST00000227237.2
N-myc downstream regulated gene 2
chr1_-_140111018 3.52 ENSMUST00000192880.6
ENSMUST00000111977.8
complement component factor h
chr6_-_141892686 3.49 ENSMUST00000042119.6
solute carrier organic anion transporter family, member 1a1
chr12_+_40495951 3.43 ENSMUST00000037488.8
dedicator of cytokinesis 4
chr19_+_4761181 3.39 ENSMUST00000008991.8
spectrin beta, non-erythrocytic 2
chr6_-_141892517 3.28 ENSMUST00000168119.8
solute carrier organic anion transporter family, member 1a1
chr9_-_36708569 3.26 ENSMUST00000163192.11
etoposide induced 2.4 mRNA
chr9_-_36708599 3.16 ENSMUST00000238932.2
ENSMUST00000115086.13
etoposide induced 2.4 mRNA
chr7_-_25239229 3.11 ENSMUST00000044547.10
ENSMUST00000066503.14
ENSMUST00000064862.13
carcinoembryonic antigen-related cell adhesion molecule 2
chr3_+_63203235 3.08 ENSMUST00000194134.6
membrane metallo endopeptidase
chr11_+_101258368 3.07 ENSMUST00000019469.3
glucose-6-phosphatase, catalytic
chr1_+_176642226 3.07 ENSMUST00000056773.15
ENSMUST00000027785.15
serologically defined colon cancer antigen 8
chr8_-_93956143 3.01 ENSMUST00000176282.2
ENSMUST00000034173.14
carboxylesterase 1E
chr17_-_59320257 2.85 ENSMUST00000174122.2
ENSMUST00000025065.12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr3_-_113367891 2.81 ENSMUST00000142505.9
amylase 1, salivary
chr16_-_91415873 2.80 ENSMUST00000143058.2
ENSMUST00000049244.10
ENSMUST00000169982.2
ENSMUST00000133731.2
DnaJ heat shock protein family (Hsp40) member C28
chr2_+_172994841 2.78 ENSMUST00000029017.6
phosphoenolpyruvate carboxykinase 1, cytosolic
chrM_+_10167 2.74 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr8_+_3543131 2.72 ENSMUST00000061508.8
ENSMUST00000207318.2
zinc finger protein 358
chr14_+_63075127 2.63 ENSMUST00000014691.10
WD repeat and FYVE domain containing 2
chr1_-_133849131 2.56 ENSMUST00000048432.6
proline arginine-rich end leucine-rich repeat
chr6_+_122285615 2.51 ENSMUST00000007602.15
ENSMUST00000112610.2
mannose-6-phosphate receptor, cation dependent
chr3_+_79792238 2.44 ENSMUST00000135021.2
golgi associated kinase 1B
chr8_-_110305672 2.43 ENSMUST00000074898.8
haptoglobin
chrM_+_9870 2.39 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr3_+_67337429 2.30 ENSMUST00000077271.9
G elongation factor, mitochondrial 1
chrX_+_99811325 2.22 ENSMUST00000000901.13
ENSMUST00000113736.9
ENSMUST00000087984.11
discs large MAGUK scaffold protein 3
chr18_-_56705960 2.22 ENSMUST00000174518.8
aldehyde dehydrogenase family 7, member A1
chr1_+_44159106 2.21 ENSMUST00000114709.3
ENSMUST00000129068.2
basic, immunoglobulin-like variable motif containing
chrX_+_20416019 2.16 ENSMUST00000023832.7
regucalcin
chr9_-_29323032 2.16 ENSMUST00000115236.2
neurotrimin
chr6_-_47790272 2.13 ENSMUST00000077290.9
protein disulfide isomerase associated 4
chr13_-_25204272 2.13 ENSMUST00000021772.4
MRS2 magnesium transporter
chr5_-_87739442 2.12 ENSMUST00000031201.9
sulfotransferase family 1E, member 1
chr4_-_129132963 2.11 ENSMUST00000097873.10
expressed sequence C77080
chr3_+_79793237 2.09 ENSMUST00000029567.9
golgi associated kinase 1B
chr7_-_103320398 2.08 ENSMUST00000062144.4
olfactory receptor 624
chrX_+_139808351 2.03 ENSMUST00000033806.5
V-set and immunoglobulin domain containing 1
chr8_-_45747883 2.03 ENSMUST00000026907.6
kallikrein B, plasma 1
chr6_+_121709891 1.82 ENSMUST00000204124.2
predicted gene 7298
chr2_+_126394327 1.80 ENSMUST00000061491.14
solute carrier family 27 (fatty acid transporter), member 2
chrX_+_138464065 1.80 ENSMUST00000113027.8
ring finger protein 128
chr15_+_39609320 1.78 ENSMUST00000227368.2
ENSMUST00000228556.2
ENSMUST00000022913.6
ENSMUST00000228701.2
ENSMUST00000227792.2
dendrocyte expressed seven transmembrane protein
chrX_+_141011173 1.76 ENSMUST00000112914.8
nuclear transport factor 2-like export factor 2
chr14_-_34032311 1.74 ENSMUST00000111917.3
ENSMUST00000228704.2
shieldin complex subunit 2
chr15_+_31602252 1.72 ENSMUST00000042702.7
ENSMUST00000161061.3
ATP synthase C subunit lysine N-methyltransferase
chr1_+_165616315 1.69 ENSMUST00000161559.3
CD247 antigen
chr2_-_160701523 1.67 ENSMUST00000103112.8
zinc fingers and homeoboxes 3
chr13_+_24511387 1.67 ENSMUST00000224953.2
ENSMUST00000050859.13
ENSMUST00000167746.8
ENSMUST00000224819.2
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chrM_+_11735 1.66 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chr11_+_4823951 1.65 ENSMUST00000038570.9
nipsnap homolog 1
chr1_-_169575203 1.64 ENSMUST00000027991.12
ENSMUST00000111357.2
regulator of G-protein signaling 4
chr3_+_89366425 1.63 ENSMUST00000029564.12
phosphomevalonate kinase
chr9_-_121745354 1.58 ENSMUST00000062474.5
cytochrome P450, family 8, subfamily b, polypeptide 1
chr1_+_171041583 1.58 ENSMUST00000111328.8
nuclear receptor subfamily 1, group I, member 3
chr13_+_93810911 1.55 ENSMUST00000048001.8
dimethylglycine dehydrogenase precursor
chr17_+_53873964 1.55 ENSMUST00000000724.15
K(lysine) acetyltransferase 2B
chr7_-_140462187 1.52 ENSMUST00000211179.2
sirtuin 3
chr1_+_171041539 1.51 ENSMUST00000005820.11
ENSMUST00000075469.12
ENSMUST00000155126.8
nuclear receptor subfamily 1, group I, member 3
chr7_-_140462221 1.51 ENSMUST00000026559.14
sirtuin 3
chr13_-_63036096 1.47 ENSMUST00000092888.11
fructose bisphosphatase 1
chr19_-_34504871 1.43 ENSMUST00000178114.2
ENSMUST00000049572.15
lysosomal acid lipase A
chrX_+_141010919 1.43 ENSMUST00000042329.12
nuclear transport factor 2-like export factor 2
chr13_-_14237958 1.41 ENSMUST00000223174.2
geranylgeranyl diphosphate synthase 1
chr5_-_31265562 1.41 ENSMUST00000201396.2
ENSMUST00000202740.4
solute carrier family 30 (zinc transporter), member 3
chrM_+_14138 1.37 ENSMUST00000082421.1
mitochondrially encoded cytochrome b
chr1_+_52884172 1.35 ENSMUST00000159352.8
ENSMUST00000044478.7
3-hydroxyisobutyryl-Coenzyme A hydrolase
chr15_-_100576715 1.34 ENSMUST00000229869.2
chymotrypsin-like elastase family, member 1
chr3_+_95801263 1.32 ENSMUST00000015894.12
aph1 homolog A, gamma secretase subunit
chrM_+_9459 1.32 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr4_-_119217079 1.30 ENSMUST00000143494.3
ENSMUST00000154606.9
coiled-coil domain containing 30
chr4_-_49549489 1.28 ENSMUST00000029987.10
aldolase B, fructose-bisphosphate
chr13_+_14238361 1.28 ENSMUST00000129488.8
ENSMUST00000110536.8
ENSMUST00000110534.8
ENSMUST00000039538.15
ENSMUST00000110533.2
AT rich interactive domain 4B (RBP1-like)
chr7_+_99659121 1.28 ENSMUST00000107084.8
chordin-like 2
chr13_+_113171645 1.24 ENSMUST00000180543.8
ENSMUST00000181568.8
ENSMUST00000109244.9
ENSMUST00000181117.8
ENSMUST00000181741.2
cell division cycle 20B
chr1_-_46927230 1.22 ENSMUST00000185520.2
solute carrier family 39 (zinc transporter), member 10
chr17_+_37083802 1.22 ENSMUST00000041531.7
histocompatibility 2, M region locus 10.5
chr17_-_40553176 1.21 ENSMUST00000026499.6
cysteine-rich secretory protein 3
chr13_-_93810808 1.21 ENSMUST00000015941.8
betaine-homocysteine methyltransferase 2
chr14_-_34032450 1.16 ENSMUST00000227375.2
shieldin complex subunit 2
chr10_+_80084955 1.15 ENSMUST00000105364.8
NADH:ubiquinone oxidoreductase core subunit S7
chr19_-_8196196 1.15 ENSMUST00000113298.9
solute carrier family 22. member 29
chr9_-_39918243 1.13 ENSMUST00000073932.4
olfactory receptor 980
chr5_+_14564932 1.10 ENSMUST00000182407.8
ENSMUST00000030691.17
piccolo (presynaptic cytomatrix protein)
chrM_-_14061 1.09 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chr4_-_148234123 1.08 ENSMUST00000126615.8
F-box protein 6
chr12_-_76224025 1.07 ENSMUST00000101291.11
ENSMUST00000218621.2
ENSMUST00000076634.5
estrogen receptor 2 (beta)
chr10_-_12689345 1.07 ENSMUST00000217899.2
utrophin
chr12_+_44268134 1.06 ENSMUST00000122902.8
patatin-like phospholipase domain containing 8
chr18_+_21134302 1.06 ENSMUST00000234107.2
ENSMUST00000072847.12
ring finger protein 138
chr1_+_131794962 1.05 ENSMUST00000112386.8
ENSMUST00000027693.8
RAB29, member RAS oncogene family
chr12_-_40495753 1.02 ENSMUST00000069692.10
ENSMUST00000069637.15
zinc finger protein 277
chr3_+_95801325 1.01 ENSMUST00000197081.2
ENSMUST00000056710.10
aph1 homolog A, gamma secretase subunit
chrX_-_84820250 1.01 ENSMUST00000113978.9
glycerol kinase
chr5_-_120610828 1.01 ENSMUST00000052258.14
ENSMUST00000031594.13
serine dehydratase-like
chr8_-_71315902 0.99 ENSMUST00000212611.2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr4_+_60003438 0.99 ENSMUST00000107517.8
ENSMUST00000107520.2
major urinary protein 6
chr14_+_11307729 0.98 ENSMUST00000160956.2
ENSMUST00000160340.8
ENSMUST00000162278.8
fragile histidine triad gene
chr7_+_18962252 0.97 ENSMUST00000063976.9
optic atrophy 3
chr9_+_107765320 0.96 ENSMUST00000191906.6
ENSMUST00000035202.4
MON1 homolog A, secretory traffciking associated
chr9_-_29323500 0.95 ENSMUST00000115237.8
neurotrimin
chr3_+_63202940 0.95 ENSMUST00000194150.6
membrane metallo endopeptidase
chr3_+_59939175 0.93 ENSMUST00000029325.5
arylacetamide deacetylase
chr5_-_91550853 0.93 ENSMUST00000121044.6
betacellulin, epidermal growth factor family member
chr3_+_108561247 0.92 ENSMUST00000124384.8
ENSMUST00000029483.15
chloride channel CLIC-like 1
chr3_-_57599956 0.90 ENSMUST00000238789.2
ENSMUST00000197088.5
ENSMUST00000099091.4
ankrin repeat and ubiquitin domain containing 1
chrM_+_7779 0.89 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chr1_+_165616250 0.89 ENSMUST00000161971.8
ENSMUST00000187313.7
ENSMUST00000178336.8
ENSMUST00000005907.12
ENSMUST00000027849.11
CD247 antigen
chr9_-_48391838 0.88 ENSMUST00000216470.2
ENSMUST00000217037.2
ENSMUST00000034524.5
ENSMUST00000213895.2
RNA exonuclease 2
chr18_+_69477541 0.88 ENSMUST00000114985.10
ENSMUST00000128706.8
ENSMUST00000201781.4
ENSMUST00000202674.4
transcription factor 4
chr13_+_63387870 0.88 ENSMUST00000159152.3
ENSMUST00000221820.2
aminopeptidase O
chr16_+_56024676 0.88 ENSMUST00000160116.8
ENSMUST00000069936.8
interphotoreceptor matrix proteoglycan 2
chr9_+_7692087 0.87 ENSMUST00000018767.8
matrix metallopeptidase 7
chr8_-_68363564 0.86 ENSMUST00000093468.12
pleckstrin and Sec7 domain containing 3
chr17_+_12803019 0.86 ENSMUST00000046959.9
ENSMUST00000233066.2
solute carrier family 22 (organic cation transporter), member 2
chr16_-_23339329 0.85 ENSMUST00000230040.2
ENSMUST00000229619.2
mannan-binding lectin serine peptidase 1
chr10_+_34359395 0.84 ENSMUST00000019913.15
fyn-related kinase
chr2_-_87322762 0.84 ENSMUST00000026957.4
PRAME like 7
chr3_+_96543143 0.82 ENSMUST00000165842.3
peroxisomal biogenesis factor 11 beta
chr10_-_121146940 0.81 ENSMUST00000064107.7
TBC1 domain family, member 30
chr13_+_47276132 0.81 ENSMUST00000068891.12
ring finger protein 144B
chr15_-_65784246 0.81 ENSMUST00000060522.11
otoconin 90
chr17_-_18498018 0.80 ENSMUST00000172190.4
ENSMUST00000231815.3
vomeronasal 2, receptor 94
chr13_+_63387827 0.80 ENSMUST00000222929.2
aminopeptidase O
chr2_+_158508609 0.80 ENSMUST00000103116.10
protein phosphatase 1, regulatory subunit 16B
chr11_-_42073737 0.79 ENSMUST00000206085.2
ENSMUST00000020707.12
ENSMUST00000132971.3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr2_+_15060051 0.77 ENSMUST00000069870.11
ENSMUST00000239125.2
ENSMUST00000193836.3
ADP-ribosylation factor-like 5B
chr15_-_65784103 0.77 ENSMUST00000079776.14
otoconin 90
chr14_-_68893253 0.77 ENSMUST00000225767.3
ENSMUST00000111072.8
ENSMUST00000022642.6
ENSMUST00000224039.2
a disintegrin and metallopeptidase domain 28
chr6_+_54241830 0.77 ENSMUST00000146114.8
chimerin 2
chr2_+_36575800 0.77 ENSMUST00000213258.2
olfactory receptor 346
chr11_+_108811626 0.75 ENSMUST00000140821.2
axin 2
chr17_-_37938000 0.75 ENSMUST00000223366.2
ENSMUST00000216128.2
olfactory receptor 115
olfactory receptor 116
chr12_+_9080014 0.74 ENSMUST00000219488.2
ENSMUST00000219470.2
tetratricopeptide repeat domain 32
chr4_-_70453140 0.73 ENSMUST00000107359.9
multiple EGF-like-domains 9
chrM_+_7758 0.72 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr14_-_63415235 0.71 ENSMUST00000054963.10
farnesyl diphosphate farnesyl transferase 1
chr19_+_46611826 0.71 ENSMUST00000111855.5
WW domain binding protein 1 like
chr11_+_21041291 0.71 ENSMUST00000093290.12
pellino 1
chr2_-_26012751 0.70 ENSMUST00000140993.2
ENSMUST00000028300.6
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr4_-_15945359 0.70 ENSMUST00000029877.9
2,4-dienoyl CoA reductase 1, mitochondrial
chrM_+_2743 0.69 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr6_+_68518603 0.69 ENSMUST00000168090.3
ENSMUST00000103326.3
immunoglobulin kappa variable 1-99
chr13_-_21726945 0.68 ENSMUST00000205976.3
ENSMUST00000175637.3
olfactory receptor 1366
chr1_-_155022501 0.68 ENSMUST00000027744.10
major histocompatibility complex, class I-related
chr4_-_114991478 0.66 ENSMUST00000106545.8
cytochrome P450, family 4, subfamily x, polypeptide 1
chr15_-_82872073 0.65 ENSMUST00000229439.2
transcription factor 20
chr10_+_34359513 0.64 ENSMUST00000170771.3
fyn-related kinase
chr17_+_46807637 0.64 ENSMUST00000046497.8
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr13_-_14237980 0.64 ENSMUST00000222687.2
ENSMUST00000221338.2
ENSMUST00000221713.2
ENSMUST00000170957.3
geranylgeranyl diphosphate synthase 1
chr10_+_28544556 0.63 ENSMUST00000161345.2
thymocyte selection associated
chr17_+_29487881 0.63 ENSMUST00000234845.2
ENSMUST00000235038.2
ENSMUST00000235050.2
ENSMUST00000120346.9
ENSMUST00000234377.2
ENSMUST00000235074.2
ENSMUST00000235040.2
ENSMUST00000234256.2
ENSMUST00000234459.2
cDNA sequence BC004004
chr1_-_130867810 0.63 ENSMUST00000112465.2
ENSMUST00000187410.7
ENSMUST00000187916.7
interleukin 19
chr11_+_108811168 0.63 ENSMUST00000052915.14
axin 2
chr4_-_114991174 0.62 ENSMUST00000051400.8
cytochrome P450, family 4, subfamily x, polypeptide 1
chr1_+_191449946 0.62 ENSMUST00000133076.7
ENSMUST00000110855.8
lysophosphatidylglycerol acyltransferase 1
chr16_-_37474772 0.61 ENSMUST00000023514.4
NADH:ubiquinone oxidoreductase subunit B4
chr18_+_13139992 0.60 ENSMUST00000041676.3
ENSMUST00000234084.2
ENSMUST00000234565.2
histamine receptor H4
chr11_-_99276868 0.60 ENSMUST00000211768.2
keratin 10
chr14_+_31058589 0.60 ENSMUST00000022451.14
calpain 7
chr7_+_106740521 0.59 ENSMUST00000210474.2
olfactory receptor 716
chr18_+_60426444 0.59 ENSMUST00000171297.2
RIKEN cDNA F830016B08 gene
chr16_-_59459745 0.58 ENSMUST00000099646.10
ADP-ribosylation factor-like 6
chr18_+_37106851 0.58 ENSMUST00000192631.2
protocadherin alpha 7
chr12_-_56583582 0.58 ENSMUST00000001536.9
NK2 homeobox 1
chr6_+_41107047 0.57 ENSMUST00000103271.2
T cell receptor beta, variable 13-3
chr15_+_25742397 0.55 ENSMUST00000135981.8
myosin X
chr2_+_30282266 0.55 ENSMUST00000028209.15
dolichyl pyrophosphate phosphatase 1
chr13_+_67052978 0.55 ENSMUST00000168767.9
predicted gene 10767
chr10_-_117074501 0.54 ENSMUST00000159193.8
ENSMUST00000020392.5
RIKEN cDNA 9530003J23 gene
chr1_-_183766195 0.54 ENSMUST00000050306.8
RIKEN cDNA 1700056E22 gene
chr12_+_87840841 0.53 ENSMUST00000110147.3
eukaryotic translation initiation factor 1A domain containing 3
chr1_+_177819001 0.53 ENSMUST00000094273.10
ENSMUST00000238506.2
ENSMUST00000239155.2
cation channel sperm associated auxiliary subunit epsilon 2
chr8_-_45863572 0.52 ENSMUST00000209651.2
ENSMUST00000211370.2
ENSMUST00000034056.12
ENSMUST00000167106.3
toll-like receptor 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 18.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
2.5 7.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
2.3 6.9 GO:0018879 biphenyl metabolic process(GO:0018879)
1.8 21.6 GO:0043651 linoleic acid metabolic process(GO:0043651)
1.5 6.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
1.4 21.0 GO:0015747 urate transport(GO:0015747)
1.2 3.6 GO:1904437 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.9 7.3 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.8 2.4 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.7 2.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.7 2.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.7 2.8 GO:0061402 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.7 3.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.7 2.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.6 6.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.6 1.8 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.6 3.6 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.6 4.0 GO:0071492 cellular response to UV-A(GO:0071492)
0.6 2.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.5 2.2 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.5 3.7 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.5 5.5 GO:0035754 B cell chemotaxis(GO:0035754)
0.5 2.9 GO:0006742 NADP catabolic process(GO:0006742)
0.4 1.8 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.4 1.7 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.4 1.6 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.4 1.1 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.3 1.0 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.3 1.3 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.3 3.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3 0.9 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.3 3.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 1.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.3 1.5 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.3 1.3 GO:0006116 NADH oxidation(GO:0006116)
0.2 6.9 GO:0032402 melanosome transport(GO:0032402)
0.2 0.7 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2 2.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 3.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.2 0.7 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.2 1.4 GO:2000054 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.2 2.5 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.2 1.2 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.2 0.8 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.2 0.6 GO:0021759 globus pallidus development(GO:0021759)
0.2 1.3 GO:0060309 elastin catabolic process(GO:0060309)
0.2 2.8 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.2 1.8 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 1.6 GO:0019695 choline metabolic process(GO:0019695)
0.2 1.4 GO:0033762 response to glucagon(GO:0033762)
0.2 0.8 GO:0044375 regulation of peroxisome size(GO:0044375)
0.2 1.1 GO:0007527 adult somatic muscle development(GO:0007527)
0.2 5.0 GO:0035634 response to stilbenoid(GO:0035634)
0.2 2.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.4 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.1 0.8 GO:0045356 regulation of dendritic cell cytokine production(GO:0002730) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 1.4 GO:0097501 stress response to metal ion(GO:0097501)
0.1 0.6 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.3 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 1.0 GO:0019532 oxalate transport(GO:0019532)
0.1 0.3 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.1 1.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.0 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.1 0.3 GO:0016598 protein arginylation(GO:0016598)
0.1 0.4 GO:0016240 autophagosome docking(GO:0016240)
0.1 4.0 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.3 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.4 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.3 GO:0006788 heme oxidation(GO:0006788)
0.1 0.2 GO:1904000 positive regulation of eating behavior(GO:1904000)
0.1 0.4 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.2 GO:0001966 thigmotaxis(GO:0001966)
0.1 0.5 GO:1990839 response to endothelin(GO:1990839)
0.1 0.6 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.1 GO:0042940 D-amino acid transport(GO:0042940)
0.1 2.1 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.5 GO:0006083 acetate metabolic process(GO:0006083)
0.1 0.3 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 1.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.6 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125) deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.3 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 1.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.4 GO:0060266 regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.3 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.9 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 0.3 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 9.3 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.1 0.3 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1 0.9 GO:0035810 positive regulation of urine volume(GO:0035810)
0.1 0.5 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 1.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 1.1 GO:0043383 negative T cell selection(GO:0043383)
0.0 2.6 GO:0070207 protein homotrimerization(GO:0070207)
0.0 7.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 2.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 3.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.8 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 1.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.9 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.9 GO:0071420 cellular response to histamine(GO:0071420)
0.0 2.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.4 GO:0019682 glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.7 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 2.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.6 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 3.6 GO:0007569 cell aging(GO:0007569)
0.0 0.5 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.5 GO:0006577 amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 1.0 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.9 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.3 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.0 0.6 GO:0097264 self proteolysis(GO:0097264)
0.0 0.7 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 2.9 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 1.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.7 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.6 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.8 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.9 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.3 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.6 GO:0009988 cell-cell recognition(GO:0009988)
0.0 0.6 GO:0031424 keratinization(GO:0031424)
0.0 7.2 GO:0016042 lipid catabolic process(GO:0016042)
0.0 1.3 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.4 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.6 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 1.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.6 GO:0001562 response to protozoan(GO:0001562)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 1.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0002355 detection of tumor cell(GO:0002355)
0.0 0.3 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.5 GO:0006879 cellular iron ion homeostasis(GO:0006879)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 3.4 GO:0008091 spectrin(GO:0008091)
0.4 1.1 GO:0044317 rod spherule(GO:0044317)
0.3 18.2 GO:0030673 axolemma(GO:0030673)
0.3 4.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 1.3 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 2.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 7.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 2.8 GO:0017119 Golgi transport complex(GO:0017119)
0.2 2.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 0.7 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.2 0.5 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 3.1 GO:0042101 T cell receptor complex(GO:0042101)
0.1 2.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.4 GO:0097632 extrinsic component of pre-autophagosomal structure membrane(GO:0097632)
0.1 13.0 GO:0070469 respiratory chain(GO:0070469)
0.1 1.6 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 3.1 GO:0034451 centriolar satellite(GO:0034451)
0.1 2.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 1.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.3 GO:0046691 intracellular canaliculus(GO:0046691)
0.1 0.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 1.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 4.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.5 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 2.5 GO:0030904 retromer complex(GO:0030904)
0.0 2.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 9.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 3.6 GO:0032420 stereocilium(GO:0032420)
0.0 1.1 GO:0070938 contractile ring(GO:0070938)
0.0 0.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0071546 pi-body(GO:0071546)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 10.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 6.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.4 GO:0000243 commitment complex(GO:0000243)
0.0 6.4 GO:0005769 early endosome(GO:0005769)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 5.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 33.7 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 20.6 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
3.1 18.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.4 10.0 GO:0004556 alpha-amylase activity(GO:0004556)
1.4 5.5 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
1.2 3.7 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
1.2 21.0 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.1 7.6 GO:0001851 complement component C3b binding(GO:0001851)
1.0 6.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.9 5.6 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.9 2.8 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.8 3.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.7 6.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.6 1.7 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity(GO:0030338)
0.6 2.2 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.5 7.4 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.5 2.0 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.5 1.4 GO:0004771 sterol esterase activity(GO:0004771)
0.5 3.8 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.5 2.9 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.4 1.6 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.4 1.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4 11.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 2.4 GO:0030492 hemoglobin binding(GO:0030492)
0.3 1.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.3 1.0 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.3 0.9 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.3 2.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.3 3.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 1.0 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.2 3.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 4.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.4 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 0.5 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 6.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 3.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.2 5.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 0.5 GO:0019807 aspartoacylase activity(GO:0019807)
0.2 3.0 GO:0070403 NAD+ binding(GO:0070403)
0.2 0.5 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 0.5 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.2 1.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 1.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 3.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.7 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 1.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.5 GO:0047874 dolichyldiphosphatase activity(GO:0047874)
0.1 2.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 1.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.1 1.5 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 1.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 2.6 GO:0005537 mannose binding(GO:0005537)
0.1 0.8 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 2.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 2.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.6 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0031768 ghrelin receptor binding(GO:0031768)
0.1 0.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 1.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.1 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.3 GO:0019809 spermidine binding(GO:0019809)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.4 GO:0070411 I-SMAD binding(GO:0070411)
0.1 2.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 11.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 5.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.7 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 5.7 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 1.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.4 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 1.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.4 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 1.2 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 1.0 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 1.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.9 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.8 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 1.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.6 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 2.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 7.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 3.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 10.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 3.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 ST P38 MAPK PATHWAY p38 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.6 8.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5 7.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.4 9.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 2.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 3.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 18.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 2.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 4.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.3 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 2.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 4.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 3.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.6 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 2.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins