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avrg: GSE58827: Dynamics of the Mouse Liver
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Results for Sox3_Sox10
Z-value: 0.78
Motif logo
Transcription factors associated with Sox3_Sox10
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
Sox3
|
ENSMUSG00000045179.10 | Sox3 |
|
Sox10
|
ENSMUSG00000033006.11 | Sox10 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Sox10 | mm39_v1_chr15_-_79048674_79048696 | 0.26 | 1.2e-01 | Click! |
| Sox3 | mm39_v1_chrX_-_59937036_59937051 | 0.03 | 8.6e-01 | Click! |
Activity profile of Sox3_Sox10 motif
Sorted Z-values of Sox3_Sox10 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of Sox3_Sox10
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 9.6 | GO:0034118 | erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118) |
| 1.5 | 4.5 | GO:0060217 | hemangioblast cell differentiation(GO:0060217) |
| 0.9 | 3.5 | GO:0046898 | response to cycloheximide(GO:0046898) |
| 0.7 | 2.2 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
| 0.7 | 2.7 | GO:0035442 | positive regulation of cellular pH reduction(GO:0032849) dipeptide transmembrane transport(GO:0035442) regulation of oligopeptide transport(GO:0090088) regulation of dipeptide transport(GO:0090089) positive regulation of oligopeptide transport(GO:2000878) positive regulation of dipeptide transport(GO:2000880) regulation of dipeptide transmembrane transport(GO:2001148) positive regulation of dipeptide transmembrane transport(GO:2001150) |
| 0.7 | 2.0 | GO:0034378 | chylomicron assembly(GO:0034378) |
| 0.6 | 2.3 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 0.6 | 4.5 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
| 0.5 | 4.4 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.5 | 3.1 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 0.4 | 2.6 | GO:1903182 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
| 0.3 | 2.8 | GO:0030035 | microspike assembly(GO:0030035) |
| 0.3 | 1.1 | GO:1990091 | sodium-dependent self proteolysis(GO:1990091) |
| 0.3 | 3.0 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 0.3 | 4.0 | GO:0034242 | negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) |
| 0.3 | 1.0 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 0.2 | 1.2 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.2 | 1.4 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 0.2 | 0.7 | GO:0045297 | mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297) seminal vesicle development(GO:0061107) |
| 0.2 | 0.8 | GO:0003290 | atrial septum secundum morphogenesis(GO:0003290) |
| 0.2 | 1.6 | GO:0002326 | B cell lineage commitment(GO:0002326) |
| 0.2 | 1.6 | GO:0033632 | regulation of cell-cell adhesion mediated by integrin(GO:0033632) |
| 0.2 | 0.6 | GO:0045660 | positive regulation of neutrophil differentiation(GO:0045660) |
| 0.2 | 0.8 | GO:1904207 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 0.2 | 4.4 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 0.2 | 1.3 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 0.2 | 0.6 | GO:0061536 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.2 | 1.1 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
| 0.2 | 0.6 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 0.2 | 1.5 | GO:0036135 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
| 0.2 | 2.5 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.2 | 2.3 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.2 | 2.6 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) |
| 0.2 | 1.1 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
| 0.2 | 1.1 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 0.2 | 0.6 | GO:0009051 | angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) pentose-phosphate shunt, oxidative branch(GO:0009051) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.2 | 0.5 | GO:0051329 | interphase(GO:0051325) mitotic interphase(GO:0051329) |
| 0.2 | 0.5 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
| 0.1 | 0.7 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) |
| 0.1 | 1.0 | GO:0010288 | response to lead ion(GO:0010288) |
| 0.1 | 0.4 | GO:0072356 | chromosome passenger complex localization to kinetochore(GO:0072356) |
| 0.1 | 0.6 | GO:1904009 | response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009) |
| 0.1 | 0.8 | GO:0031133 | regulation of axon diameter(GO:0031133) |
| 0.1 | 0.8 | GO:1902963 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.1 | 0.4 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 0.1 | 0.7 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 0.1 | 2.8 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.1 | 0.5 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) |
| 0.1 | 0.4 | GO:0006285 | base-excision repair, AP site formation(GO:0006285) |
| 0.1 | 0.3 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.1 | 0.4 | GO:0015825 | L-serine transport(GO:0015825) |
| 0.1 | 1.5 | GO:0035879 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.1 | 1.8 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.1 | 0.9 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.1 | 0.3 | GO:0036145 | dendritic cell homeostasis(GO:0036145) |
| 0.1 | 0.2 | GO:0002343 | peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344) |
| 0.1 | 0.8 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.1 | 2.1 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 0.1 | 0.6 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.1 | 0.3 | GO:0000451 | rRNA 2'-O-methylation(GO:0000451) |
| 0.1 | 1.2 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 0.8 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
| 0.1 | 1.3 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.1 | 2.4 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.1 | 0.3 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
| 0.1 | 0.5 | GO:0009597 | detection of virus(GO:0009597) |
| 0.1 | 0.3 | GO:0098749 | cerebellar neuron development(GO:0098749) |
| 0.1 | 0.5 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 0.1 | 1.1 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
| 0.1 | 0.6 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 0.1 | 0.4 | GO:0046351 | disaccharide biosynthetic process(GO:0046351) |
| 0.1 | 0.4 | GO:0071226 | positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) cellular response to molecule of fungal origin(GO:0071226) |
| 0.1 | 0.4 | GO:0060221 | retinal rod cell differentiation(GO:0060221) |
| 0.1 | 0.3 | GO:0001543 | ovarian follicle rupture(GO:0001543) |
| 0.1 | 1.3 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.1 | 0.3 | GO:0090367 | negative regulation of mRNA modification(GO:0090367) |
| 0.1 | 0.4 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
| 0.1 | 0.5 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.1 | 2.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 0.3 | GO:0070649 | formin-nucleated actin cable assembly(GO:0070649) |
| 0.1 | 0.3 | GO:0019417 | sulfur oxidation(GO:0019417) |
| 0.1 | 0.7 | GO:0010897 | negative regulation of triglyceride catabolic process(GO:0010897) |
| 0.1 | 0.7 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.1 | 0.5 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
| 0.1 | 0.3 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.1 | 1.1 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.1 | 0.2 | GO:0030472 | mitotic spindle organization in nucleus(GO:0030472) |
| 0.1 | 0.5 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 0.1 | 0.4 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
| 0.1 | 0.6 | GO:0060313 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 0.1 | 0.5 | GO:0021888 | hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) |
| 0.1 | 0.5 | GO:0006868 | glutamine transport(GO:0006868) |
| 0.1 | 0.2 | GO:0061511 | centriole elongation(GO:0061511) |
| 0.1 | 0.2 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 0.1 | 0.3 | GO:1902896 | terminal web assembly(GO:1902896) |
| 0.1 | 0.5 | GO:0060948 | cardiac vascular smooth muscle cell development(GO:0060948) |
| 0.1 | 0.2 | GO:2000744 | anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744) |
| 0.1 | 0.3 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
| 0.1 | 0.2 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
| 0.1 | 0.3 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 0.1 | 0.1 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 0.1 | 0.2 | GO:1990428 | miRNA transport(GO:1990428) |
| 0.1 | 0.5 | GO:0036506 | maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 0.1 | 0.3 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.1 | 0.4 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.1 | 0.3 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 0.1 | 0.2 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.1 | 0.3 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
| 0.1 | 0.2 | GO:0097276 | creatinine homeostasis(GO:0097273) cellular ammonia homeostasis(GO:0097275) cellular creatinine homeostasis(GO:0097276) cellular urea homeostasis(GO:0097277) |
| 0.1 | 0.6 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.1 | 0.9 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.1 | 0.1 | GO:0003273 | cell migration involved in endocardial cushion formation(GO:0003273) |
| 0.1 | 0.1 | GO:0003162 | atrioventricular node development(GO:0003162) |
| 0.1 | 0.3 | GO:0015960 | diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) |
| 0.1 | 0.2 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.1 | 0.2 | GO:0007228 | positive regulation of hh target transcription factor activity(GO:0007228) |
| 0.1 | 0.5 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.1 | 1.1 | GO:0035090 | maintenance of apical/basal cell polarity(GO:0035090) |
| 0.1 | 0.5 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.1 | 0.4 | GO:0033277 | abortive mitotic cell cycle(GO:0033277) |
| 0.1 | 1.3 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.1 | 0.2 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
| 0.1 | 1.0 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.1 | 0.3 | GO:0035822 | meiotic gene conversion(GO:0006311) gene conversion(GO:0035822) |
| 0.0 | 0.2 | GO:0031394 | positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
| 0.0 | 0.6 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) regulation of apoptotic DNA fragmentation(GO:1902510) |
| 0.0 | 0.0 | GO:0033030 | negative regulation of neutrophil apoptotic process(GO:0033030) |
| 0.0 | 0.1 | GO:1903896 | positive regulation of IRE1-mediated unfolded protein response(GO:1903896) |
| 0.0 | 0.2 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
| 0.0 | 1.0 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 0.0 | 0.2 | GO:0061188 | regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188) |
| 0.0 | 0.2 | GO:0060398 | regulation of growth hormone receptor signaling pathway(GO:0060398) |
| 0.0 | 0.2 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 0.0 | 0.1 | GO:0052055 | modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) |
| 0.0 | 0.2 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.0 | 0.3 | GO:0060686 | esophagus smooth muscle contraction(GO:0014846) negative regulation of prostatic bud formation(GO:0060686) |
| 0.0 | 0.4 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.0 | 0.3 | GO:2001205 | negative regulation of osteoclast development(GO:2001205) |
| 0.0 | 0.1 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
| 0.0 | 0.1 | GO:0060821 | inactivation of X chromosome by DNA methylation(GO:0060821) |
| 0.0 | 0.7 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
| 0.0 | 0.7 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.2 | GO:1902081 | regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) |
| 0.0 | 0.2 | GO:0035795 | negative regulation of mitochondrial membrane permeability(GO:0035795) |
| 0.0 | 0.2 | GO:0051582 | positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) |
| 0.0 | 0.2 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 0.0 | 0.1 | GO:0033189 | response to vitamin A(GO:0033189) |
| 0.0 | 0.1 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 0.0 | 0.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.0 | 0.1 | GO:2000118 | regulation of sodium-dependent phosphate transport(GO:2000118) |
| 0.0 | 1.6 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.0 | 0.2 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 0.0 | 0.2 | GO:1903751 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 0.0 | 0.5 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.0 | 0.5 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
| 0.0 | 0.2 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.0 | 0.2 | GO:0086023 | adrenergic receptor signaling pathway involved in heart process(GO:0086023) |
| 0.0 | 0.1 | GO:2000481 | positive regulation of cAMP-dependent protein kinase activity(GO:2000481) |
| 0.0 | 0.1 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.0 | 0.1 | GO:0040010 | positive regulation of growth rate(GO:0040010) |
| 0.0 | 0.2 | GO:1902808 | positive regulation of cell cycle G1/S phase transition(GO:1902808) |
| 0.0 | 0.1 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.0 | 0.3 | GO:0001835 | blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
| 0.0 | 0.1 | GO:1902164 | positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) |
| 0.0 | 0.5 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.0 | 0.2 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.0 | 0.1 | GO:0010966 | regulation of phosphate transport(GO:0010966) |
| 0.0 | 0.3 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.0 | 0.4 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 0.0 | 0.3 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.0 | 5.0 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 0.6 | GO:0046457 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
| 0.0 | 0.6 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.0 | 0.1 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.0 | 0.1 | GO:0046021 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
| 0.0 | 0.1 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) |
| 0.0 | 1.5 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 2.1 | GO:0001541 | ovarian follicle development(GO:0001541) |
| 0.0 | 0.4 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.0 | 3.3 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.0 | 0.2 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.0 | 0.4 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
| 0.0 | 0.3 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.0 | 0.1 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 0.0 | 0.7 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.0 | 0.2 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
| 0.0 | 0.1 | GO:0055011 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 0.0 | 0.8 | GO:1990845 | adaptive thermogenesis(GO:1990845) |
| 0.0 | 0.7 | GO:0021860 | pyramidal neuron development(GO:0021860) |
| 0.0 | 0.3 | GO:0051461 | positive regulation of corticotropin secretion(GO:0051461) |
| 0.0 | 0.2 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 0.0 | 0.3 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.1 | GO:0008594 | photoreceptor cell morphogenesis(GO:0008594) |
| 0.0 | 0.2 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
| 0.0 | 0.1 | GO:0098912 | membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) |
| 0.0 | 0.1 | GO:2000078 | positive regulation of type B pancreatic cell development(GO:2000078) |
| 0.0 | 0.1 | GO:0071544 | diphosphoinositol polyphosphate catabolic process(GO:0071544) |
| 0.0 | 0.5 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 0.7 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 0.2 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.0 | 0.2 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 0.0 | 0.1 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.0 | 0.2 | GO:0038094 | Fc-gamma receptor signaling pathway(GO:0038094) |
| 0.0 | 0.1 | GO:2000328 | regulation of T-helper 17 cell lineage commitment(GO:2000328) |
| 0.0 | 0.2 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.0 | 0.1 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 0.0 | 0.2 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 0.0 | 0.5 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
| 0.0 | 0.1 | GO:2001200 | positive regulation of dendritic cell differentiation(GO:2001200) |
| 0.0 | 0.1 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
| 0.0 | 1.3 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
| 0.0 | 0.1 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 0.0 | 0.1 | GO:0002304 | gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305) |
| 0.0 | 0.1 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.0 | 0.3 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
| 0.0 | 0.9 | GO:0035411 | catenin import into nucleus(GO:0035411) |
| 0.0 | 0.1 | GO:2000646 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) positive regulation of receptor catabolic process(GO:2000646) |
| 0.0 | 0.2 | GO:0019661 | glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
| 0.0 | 0.8 | GO:0009299 | mRNA transcription(GO:0009299) |
| 0.0 | 0.6 | GO:0030220 | platelet formation(GO:0030220) |
| 0.0 | 0.3 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.0 | 0.0 | GO:0001922 | B-1 B cell homeostasis(GO:0001922) |
| 0.0 | 0.2 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 0.4 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.0 | 0.2 | GO:1904672 | regulation of somatic stem cell population maintenance(GO:1904672) |
| 0.0 | 0.2 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 0.0 | 0.8 | GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042) |
| 0.0 | 0.1 | GO:0030576 | Cajal body organization(GO:0030576) |
| 0.0 | 0.5 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.2 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.0 | 0.1 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 0.3 | GO:0086036 | regulation of cardiac muscle cell membrane potential(GO:0086036) |
| 0.0 | 0.2 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 0.0 | 0.1 | GO:2000656 | MAPK import into nucleus(GO:0000189) regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657) |
| 0.0 | 0.1 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
| 0.0 | 0.2 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.0 | 0.2 | GO:1904251 | regulation of bile acid metabolic process(GO:1904251) |
| 0.0 | 0.1 | GO:0045212 | neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.0 | 0.1 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
| 0.0 | 0.1 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
| 0.0 | 0.1 | GO:0070543 | response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 0.0 | 0.1 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.0 | 0.4 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.0 | 0.3 | GO:0006379 | mRNA cleavage(GO:0006379) |
| 0.0 | 0.2 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
| 0.0 | 0.1 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.0 | 0.2 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
| 0.0 | 0.1 | GO:0061366 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
| 0.0 | 0.4 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 0.0 | GO:0009609 | response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) |
| 0.0 | 0.4 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.0 | 0.7 | GO:0043631 | mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631) |
| 0.0 | 0.4 | GO:0006541 | glutamine metabolic process(GO:0006541) |
| 0.0 | 0.0 | GO:1904306 | positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306) |
| 0.0 | 0.0 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.0 | 0.3 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.0 | 0.4 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 0.1 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
| 0.0 | 0.3 | GO:0046185 | aldehyde catabolic process(GO:0046185) |
| 0.0 | 0.1 | GO:0071850 | mitotic cell cycle arrest(GO:0071850) |
| 0.0 | 0.0 | GO:0061723 | glycophagy(GO:0061723) |
| 0.0 | 0.2 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.0 | 0.1 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.0 | 0.1 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.0 | 0.1 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.1 | GO:0021840 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) |
| 0.0 | 0.2 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.0 | 0.2 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.0 | 0.3 | GO:0030903 | notochord development(GO:0030903) |
| 0.0 | 1.6 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
| 0.0 | 0.3 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 0.3 | GO:0090026 | positive regulation of monocyte chemotaxis(GO:0090026) |
| 0.0 | 0.2 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 0.2 | GO:0070102 | interleukin-6-mediated signaling pathway(GO:0070102) |
| 0.0 | 0.1 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.0 | 0.5 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.0 | 0.0 | GO:0061762 | CAMKK-AMPK signaling cascade(GO:0061762) |
| 0.0 | 0.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.2 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.5 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.0 | 0.1 | GO:0061577 | calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) |
| 0.0 | 0.1 | GO:0010940 | positive regulation of necrotic cell death(GO:0010940) |
| 0.0 | 1.0 | GO:2000045 | regulation of G1/S transition of mitotic cell cycle(GO:2000045) |
| 0.0 | 0.1 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.0 | 0.4 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.1 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.0 | 0.3 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.0 | 0.1 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.0 | 0.0 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 0.0 | 0.1 | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639) |
| 0.0 | 0.1 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
| 0.0 | 0.2 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.1 | GO:0010818 | T cell chemotaxis(GO:0010818) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 4.5 | GO:0033193 | Lsd1/2 complex(GO:0033193) |
| 0.7 | 4.4 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.5 | 2.6 | GO:0044393 | microspike(GO:0044393) |
| 0.5 | 1.9 | GO:0008623 | CHRAC(GO:0008623) |
| 0.4 | 2.6 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
| 0.4 | 9.5 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.3 | 3.5 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.3 | 1.0 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 0.2 | 2.0 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.2 | 4.4 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.2 | 1.4 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.2 | 1.1 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.2 | 0.7 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 0.2 | 0.9 | GO:0042585 | germinal vesicle(GO:0042585) |
| 0.1 | 0.7 | GO:0071914 | prominosome(GO:0071914) |
| 0.1 | 0.9 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.1 | 0.7 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 0.1 | 0.8 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.1 | 1.0 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.1 | 0.9 | GO:0005638 | lamin filament(GO:0005638) |
| 0.1 | 0.2 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.1 | 0.8 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.1 | 0.6 | GO:0043293 | apoptosome(GO:0043293) |
| 0.1 | 1.3 | GO:0097451 | glial limiting end-foot(GO:0097451) |
| 0.1 | 1.1 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.1 | 0.3 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.1 | 1.2 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.1 | 0.6 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.1 | 0.5 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.1 | 1.0 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.1 | 0.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.1 | 0.2 | GO:0034455 | t-UTP complex(GO:0034455) |
| 0.1 | 0.3 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.1 | 0.5 | GO:0031523 | Myb complex(GO:0031523) |
| 0.1 | 1.1 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.1 | 0.5 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.1 | 0.9 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.1 | 0.2 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.1 | 0.2 | GO:0090537 | CERF complex(GO:0090537) |
| 0.1 | 1.1 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.1 | 0.5 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.1 | 0.2 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.1 | 0.5 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.1 | 0.4 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.1 | 0.2 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.1 | 0.4 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.1 | 0.2 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 0.1 | 0.4 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.0 | 0.8 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.3 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 0.7 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.0 | 3.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 0.3 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.0 | 0.5 | GO:0060091 | kinocilium(GO:0060091) |
| 0.0 | 0.7 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 0.2 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
| 0.0 | 0.3 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 1.1 | GO:0042581 | specific granule(GO:0042581) |
| 0.0 | 0.2 | GO:0061673 | mitotic spindle astral microtubule(GO:0061673) |
| 0.0 | 0.2 | GO:0031680 | G-protein beta/gamma-subunit complex(GO:0031680) |
| 0.0 | 0.4 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 1.7 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 0.5 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 0.4 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.0 | 0.8 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.3 | GO:1990752 | microtubule end(GO:1990752) |
| 0.0 | 0.1 | GO:0002095 | caveolar macromolecular signaling complex(GO:0002095) |
| 0.0 | 0.4 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.0 | 0.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 1.8 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.7 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 0.4 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 0.1 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.0 | 0.6 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.5 | GO:0051286 | cell tip(GO:0051286) |
| 0.0 | 0.2 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.0 | 0.5 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 0.8 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.0 | 2.6 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.1 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.0 | 0.2 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.0 | 2.6 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 1.6 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.0 | 0.5 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.0 | 3.0 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 0.7 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.2 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.0 | 4.3 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 0.3 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
| 0.0 | 0.1 | GO:0070722 | Tle3-Aes complex(GO:0070722) |
| 0.0 | 2.5 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 2.0 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.1 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.0 | 0.1 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.0 | 0.3 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.2 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.0 | 0.2 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.0 | 2.1 | GO:0005930 | axoneme(GO:0005930) |
| 0.0 | 0.2 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.0 | 1.3 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.1 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.0 | 0.2 | GO:0032009 | early phagosome(GO:0032009) |
| 0.0 | 0.2 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.0 | 0.6 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.0 | 0.2 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.0 | 0.1 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.0 | 0.2 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.0 | 0.1 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.0 | 0.1 | GO:0002177 | manchette(GO:0002177) |
| 0.0 | 0.2 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 0.3 | GO:0045120 | pronucleus(GO:0045120) |
| 0.0 | 0.1 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.0 | 0.2 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.1 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 0.1 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 0.0 | 0.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.1 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 0.6 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.1 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.5 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.1 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.0 | 0.1 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.0 | 0.1 | GO:0005914 | spot adherens junction(GO:0005914) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 4.3 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 0.7 | 4.4 | GO:0016728 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.6 | 2.2 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.5 | 3.1 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
| 0.4 | 2.6 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
| 0.4 | 9.6 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.3 | 3.5 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.3 | 0.9 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 0.3 | 2.7 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.2 | 2.8 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.2 | 1.8 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
| 0.2 | 1.0 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.2 | 1.1 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.2 | 0.5 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.1 | 2.2 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 0.1 | GO:0031762 | alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762) |
| 0.1 | 0.4 | GO:0004356 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) |
| 0.1 | 0.4 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 0.1 | 0.6 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 0.1 | 2.8 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.1 | 1.5 | GO:1990715 | mRNA CDS binding(GO:1990715) |
| 0.1 | 0.8 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.1 | 0.4 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.1 | 0.6 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 0.1 | 1.9 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 0.6 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.1 | 0.3 | GO:0070039 | rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039) |
| 0.1 | 0.8 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.1 | 0.9 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.1 | 1.1 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.1 | 0.2 | GO:0032129 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 0.1 | 0.4 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.1 | 1.9 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 0.4 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 0.1 | 0.7 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.1 | 0.8 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.1 | 0.5 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.1 | 0.2 | GO:0045142 | ATP-dependent DNA/RNA helicase activity(GO:0033680) triplex DNA binding(GO:0045142) |
| 0.1 | 0.5 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.1 | 0.7 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.1 | 6.1 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 1.1 | GO:0031432 | titin binding(GO:0031432) |
| 0.1 | 0.2 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
| 0.1 | 0.5 | GO:0052723 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.1 | 0.5 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.1 | 0.2 | GO:0005302 | L-tyrosine transmembrane transporter activity(GO:0005302) |
| 0.1 | 2.8 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.1 | 0.9 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.1 | 0.2 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.1 | 0.4 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.1 | 0.5 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.1 | 0.3 | GO:0038025 | reelin receptor activity(GO:0038025) |
| 0.1 | 3.7 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 0.4 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.1 | 0.2 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.1 | 0.3 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
| 0.1 | 0.5 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 0.4 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 0.1 | 1.2 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 0.6 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.1 | 0.9 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 0.6 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.1 | 0.2 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) |
| 0.1 | 0.8 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.1 | 0.6 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.1 | 11.5 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.1 | 0.5 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.1 | 0.4 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.1 | 0.7 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
| 0.0 | 0.5 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.0 | 0.2 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.0 | 0.1 | GO:0016781 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
| 0.0 | 0.7 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.0 | 0.4 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.0 | 1.1 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 1.4 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.0 | 0.7 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 0.2 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.0 | 0.2 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
| 0.0 | 0.5 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.0 | 0.5 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
| 0.0 | 0.2 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 0.0 | 0.2 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.0 | 0.3 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.6 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.0 | 2.0 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.2 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.0 | 0.3 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.0 | 0.1 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.0 | 0.1 | GO:0015275 | stretch-activated, cation-selective, calcium channel activity(GO:0015275) |
| 0.0 | 0.8 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 0.1 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.0 | 0.5 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.0 | 0.3 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 0.0 | 0.4 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.0 | 0.3 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.0 | 0.1 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) |
| 0.0 | 1.2 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.4 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 1.1 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
| 0.0 | 0.3 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.0 | 0.3 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
| 0.0 | 0.2 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.0 | 2.2 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 1.6 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 3.1 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.6 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 0.0 | 0.2 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.0 | 0.1 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 0.0 | 1.0 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.5 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 0.1 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.0 | 0.2 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.0 | 0.1 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.0 | 0.2 | GO:0019158 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.0 | 0.1 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.0 | 0.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.1 | GO:0015100 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.0 | 0.2 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 0.0 | 0.1 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.0 | 0.2 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.0 | 0.1 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
| 0.0 | 0.3 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 0.0 | 0.2 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 0.2 | GO:0005113 | patched binding(GO:0005113) |
| 0.0 | 0.1 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 0.0 | 0.2 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.0 | 0.1 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.0 | 0.3 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.0 | 0.2 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.0 | 0.6 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 0.1 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
| 0.0 | 0.2 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.0 | 0.2 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 0.0 | 0.2 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.1 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.0 | 4.1 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 0.4 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 0.6 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 1.0 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.0 | 0.2 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.0 | 0.2 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.2 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.0 | 0.9 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.1 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
| 0.0 | 0.1 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.0 | 1.3 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 0.4 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
| 0.0 | 0.1 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 0.0 | 0.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.2 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.0 | 0.4 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.0 | 0.1 | GO:0070052 | collagen V binding(GO:0070052) |
| 0.0 | 0.3 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.0 | 0.2 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.0 | 1.9 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 0.1 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.0 | 0.1 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.0 | 0.3 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.1 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.0 | 0.2 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.0 | 0.2 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.0 | 0.2 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.5 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.4 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.0 | 0.2 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 0.3 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
| 0.0 | 0.4 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 0.3 | GO:0030295 | protein kinase activator activity(GO:0030295) |
| 0.0 | 0.3 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 0.0 | GO:0003681 | bent DNA binding(GO:0003681) |
| 0.0 | 0.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.3 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.0 | 2.3 | GO:0003774 | motor activity(GO:0003774) |
| 0.0 | 0.3 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 0.1 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.0 | 0.0 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.0 | 0.2 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 0.2 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.0 | 0.7 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.0 | 0.1 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.0 | 0.1 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 0.0 | 0.1 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.0 | 0.5 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.1 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.0 | 0.1 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.0 | 0.4 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.5 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.3 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.2 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.0 | 0.0 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.0 | 0.2 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.1 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.2 | 1.0 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 3.1 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 5.7 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 2.3 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.1 | 7.7 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 4.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 2.2 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 2.1 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.1 | 3.3 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 2.8 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 1.2 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 0.5 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 1.4 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 0.6 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.0 | 1.3 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 0.4 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 0.7 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 0.1 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.8 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.5 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 0.7 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.4 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.5 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 0.2 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.0 | 0.4 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 0.3 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.4 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.5 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 0.1 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.0 | 0.6 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.0 | 0.9 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.9 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 0.3 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.0 | 0.8 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.0 | 0.1 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.2 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.0 | 0.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 0.2 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.2 | PID ENDOTHELIN PATHWAY | Endothelins |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.4 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.2 | 3.5 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.1 | 3.2 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 3.9 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.1 | 0.3 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.1 | 0.9 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.1 | 2.2 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 3.4 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 1.2 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 0.6 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.1 | 1.3 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.1 | 1.6 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 1.2 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.5 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.0 | 1.1 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.0 | 2.3 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 0.5 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 5.0 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.3 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.0 | 0.4 | REACTOME ACYL CHAIN REMODELLING OF PC | Genes involved in Acyl chain remodelling of PC |
| 0.0 | 1.6 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 2.2 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 5.3 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.2 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 0.0 | 1.3 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.9 | REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
| 0.0 | 0.6 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.0 | 0.3 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.0 | 0.9 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.0 | 1.1 | REACTOME G PROTEIN BETA GAMMA SIGNALLING | Genes involved in G-protein beta:gamma signalling |
| 0.0 | 0.3 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.3 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.4 | REACTOME PD1 SIGNALING | Genes involved in PD-1 signaling |
| 0.0 | 2.0 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 0.1 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.0 | 0.9 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 0.2 | REACTOME MRNA CAPPING | Genes involved in mRNA Capping |
| 0.0 | 0.2 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.0 | 0.9 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.0 | 0.9 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.6 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.0 | 0.4 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 0.4 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.0 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 0.0 | 1.8 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 0.7 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.2 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.0 | 1.0 | REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | Genes involved in Recruitment of mitotic centrosome proteins and complexes |
| 0.0 | 0.6 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 0.3 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 0.3 | REACTOME MEIOSIS | Genes involved in Meiosis |
| 0.0 | 0.3 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.1 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 0.6 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.2 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |