avrg: GSE58827: Dynamics of the Mouse Liver

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Spib Links Ensembl NCBI MGI UniProt	ENSMUSG00000008193.14	Spib

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Spib	mm39_v1_chr7_-_44181477_44181502	0.87	5.8e-12	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr6_-_136918671 Show fit	41.29	ENSMUST00000032344.12	Arhgdib Links Ensembl NCBI MGI UniProt Show fit	Rho, GDP dissociation inhibitor (GDI) beta
chr14_+_80237691 Show fit	34.37	ENSMUST00000228749.2 ENSMUST00000088735.4	Olfm4 Links Ensembl NCBI MGI UniProt Show fit	olfactomedin 4
chr5_+_149201577 Show fit	27.78	ENSMUST00000071130.5	Alox5ap Links Ensembl NCBI MGI UniProt Show fit	arachidonate 5-lipoxygenase activating protein
chr11_-_103235475 Show fit	23.58	ENSMUST00000041385.14	Arhgap27 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 27
chr11_-_16958647 Show fit	23.27	ENSMUST00000102881.10	Plek Links Ensembl NCBI MGI UniProt Show fit	pleckstrin
chr5_+_149202157 Show fit	23.20	ENSMUST00000200806.4	Alox5ap Links Ensembl NCBI MGI UniProt Show fit	arachidonate 5-lipoxygenase activating protein
chr5_-_134258435 Show fit	23.06	ENSMUST00000016094.13 ENSMUST00000111275.8 ENSMUST00000144086.2	Ncf1 Links Ensembl NCBI MGI UniProt Show fit	neutrophil cytosolic factor 1
chr9_+_55997246 Show fit	22.82	ENSMUST00000059206.8	Pstpip1 Links Ensembl NCBI MGI UniProt Show fit	proline-serine-threonine phosphatase-interacting protein 1
chr15_-_66684442 Show fit	22.80	ENSMUST00000100572.10	Sla Links Ensembl NCBI MGI UniProt Show fit	src-like adaptor
chr7_+_99184645 Show fit	20.94	ENSMUST00000098266.9 ENSMUST00000179755.8	Arrb1 Links Ensembl NCBI MGI UniProt Show fit	arrestin, beta 1
chr11_+_11635908 Show fit	20.51	ENSMUST00000065433.12	Ikzf1 Links Ensembl NCBI MGI UniProt Show fit	IKAROS family zinc finger 1
chr7_-_44888220 Show fit	20.27	ENSMUST00000210372.2 ENSMUST00000209779.2 ENSMUST00000098461.10 ENSMUST00000211373.2	Cd37 Links Ensembl NCBI MGI UniProt Show fit	CD37 antigen
chr7_-_126303351 Show fit	19.80	ENSMUST00000106364.8	Coro1a Links Ensembl NCBI MGI UniProt Show fit	coronin, actin binding protein 1A
chr6_-_136918495 Show fit	19.69	ENSMUST00000111892.8	Arhgdib Links Ensembl NCBI MGI UniProt Show fit	Rho, GDP dissociation inhibitor (GDI) beta
chr7_-_126303887 Show fit	19.65	ENSMUST00000131415.8	Coro1a Links Ensembl NCBI MGI UniProt Show fit	coronin, actin binding protein 1A
chr15_+_78210190 Show fit	19.24	ENSMUST00000229034.2 ENSMUST00000096355.4	Csf2rb Links Ensembl NCBI MGI UniProt Show fit	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr7_-_45570828 Show fit	19.07	ENSMUST00000038876.13	Emp3 Links Ensembl NCBI MGI UniProt Show fit	epithelial membrane protein 3
chr1_-_170886924 Show fit	18.71	ENSMUST00000164044.8 ENSMUST00000169017.8	Fcgr3 Links Ensembl NCBI MGI UniProt Show fit	Fc receptor, IgG, low affinity III
chr2_-_181333597 Show fit	18.36	ENSMUST00000108778.8 ENSMUST00000165416.8	Rgs19 Links Ensembl NCBI MGI UniProt Show fit	regulator of G-protein signaling 19
chr2_+_24235300 Show fit	18.15	ENSMUST00000114485.9 ENSMUST00000114482.3	Il1rn Links Ensembl NCBI MGI UniProt Show fit	interleukin 1 receptor antagonist
chr14_-_70864448 Show fit	18.14	ENSMUST00000110984.4	Dmtn Links Ensembl NCBI MGI UniProt Show fit	dematin actin binding protein
chr15_+_78210242 Show fit	17.95	ENSMUST00000229678.2 ENSMUST00000231888.2	Csf2rb Links Ensembl NCBI MGI UniProt Show fit	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr17_+_57586094 Show fit	17.38	ENSMUST00000169220.9 ENSMUST00000005889.16 ENSMUST00000112870.5	Vav1 Links Ensembl NCBI MGI UniProt Show fit	vav 1 oncogene
chr15_-_63932176 Show fit	17.08	ENSMUST00000226675.2 ENSMUST00000228226.2 ENSMUST00000227024.2	Cyrib Links Ensembl NCBI MGI UniProt Show fit	CYFIP related Rac1 interactor B
chr15_-_78189917 Show fit	16.87	ENSMUST00000096356.5	Csf2rb2 Links Ensembl NCBI MGI UniProt Show fit	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr2_+_22664094 Show fit	16.83	ENSMUST00000014290.15	Apbb1ip Links Ensembl NCBI MGI UniProt Show fit	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr11_-_34674677 Show fit	16.71	ENSMUST00000093193.12 ENSMUST00000101365.9	Dock2 Links Ensembl NCBI MGI UniProt Show fit	dedicator of cyto-kinesis 2
chr7_-_45570538 Show fit	16.61	ENSMUST00000210297.2	Emp3 Links Ensembl NCBI MGI UniProt Show fit	epithelial membrane protein 3
chr4_+_130640611 Show fit	16.58	ENSMUST00000156225.8 ENSMUST00000156742.8	Laptm5 Links Ensembl NCBI MGI UniProt Show fit	lysosomal-associated protein transmembrane 5
chr15_-_36609208 Show fit	16.22	ENSMUST00000001809.15	Pabpc1 Links Ensembl NCBI MGI UniProt Show fit	poly(A) binding protein, cytoplasmic 1
chr2_-_165242307 Show fit	16.16	ENSMUST00000029213.5	Ocstamp Links Ensembl NCBI MGI UniProt Show fit	osteoclast stimulatory transmembrane protein
chr15_+_78209920 Show fit	16.08	ENSMUST00000230264.3	Csf2rb Links Ensembl NCBI MGI UniProt Show fit	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr9_-_114610879 Show fit	15.94	ENSMUST00000084867.9 ENSMUST00000216760.2 ENSMUST00000035009.16	Cmtm7 Links Ensembl NCBI MGI UniProt Show fit	CKLF-like MARVEL transmembrane domain containing 7
chr15_-_78456898 Show fit	15.93	ENSMUST00000043214.8	Rac2 Links Ensembl NCBI MGI UniProt Show fit	Rac family small GTPase 2
chr1_-_170755136 Show fit	15.91	ENSMUST00000046322.14 ENSMUST00000159171.2	Fcrla Links Ensembl NCBI MGI UniProt Show fit	Fc receptor-like A
chr6_+_38895902 Show fit	15.73	ENSMUST00000003017.13	Tbxas1 Links Ensembl NCBI MGI UniProt Show fit	thromboxane A synthase 1, platelet
chr14_-_70864666 Show fit	15.40	ENSMUST00000022694.17	Dmtn Links Ensembl NCBI MGI UniProt Show fit	dematin actin binding protein
chr4_+_140428777 Show fit	15.31	ENSMUST00000138808.8 ENSMUST00000038893.6	Rcc2 Links Ensembl NCBI MGI UniProt Show fit	regulator of chromosome condensation 2
chr15_-_82917495 Show fit	15.19	ENSMUST00000231165.2	Nfam1 Links Ensembl NCBI MGI UniProt Show fit	Nfat activating molecule with ITAM motif 1
chr2_-_181335697 Show fit	15.19	ENSMUST00000108779.8 ENSMUST00000108769.8 ENSMUST00000108772.8	Rgs19 Links Ensembl NCBI MGI UniProt Show fit	regulator of G-protein signaling 19
chr4_+_130640436 Show fit	15.09	ENSMUST00000151698.8	Laptm5 Links Ensembl NCBI MGI UniProt Show fit	lysosomal-associated protein transmembrane 5
chr19_+_4204605 Show fit	15.05	ENSMUST00000061086.9	Ptprcap Links Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr7_-_45570674 Show fit	14.95	ENSMUST00000210939.2	Emp3 Links Ensembl NCBI MGI UniProt Show fit	epithelial membrane protein 3
chr15_+_103362195 Show fit	14.94	ENSMUST00000047405.9	Nckap1l Links Ensembl NCBI MGI UniProt Show fit	NCK associated protein 1 like
chr17_+_35268942 Show fit	14.86	ENSMUST00000007257.10	Clic1 Links Ensembl NCBI MGI UniProt Show fit	chloride intracellular channel 1
chr6_+_129326927 Show fit	14.75	ENSMUST00000065289.6	Clec12a Links Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 12, member a
chr13_-_113237505 Show fit	14.53	ENSMUST00000224282.2 ENSMUST00000023897.7	Gzma Links Ensembl NCBI MGI UniProt Show fit	granzyme A
chr15_-_78189822 Show fit	13.94	ENSMUST00000230115.3	Csf2rb2 Links Ensembl NCBI MGI UniProt Show fit	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr7_-_126303689 Show fit	13.92	ENSMUST00000135087.8	Coro1a Links Ensembl NCBI MGI UniProt Show fit	coronin, actin binding protein 1A
chr1_-_171061902 Show fit	13.69	ENSMUST00000079957.12	Fcer1g Links Ensembl NCBI MGI UniProt Show fit	Fc receptor, IgE, high affinity I, gamma polypeptide
chr7_-_44888532 Show fit	13.65	ENSMUST00000033063.15	Cd37 Links Ensembl NCBI MGI UniProt Show fit	CD37 antigen
chr13_+_20978283 Show fit	13.13	ENSMUST00000021757.5 ENSMUST00000221982.2	Aoah Links Ensembl NCBI MGI UniProt Show fit	acyloxyacyl hydrolase
chr2_-_38895586 Show fit	12.97	ENSMUST00000080861.6	Rpl35 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein L35
chr7_-_44888465 Show fit	12.55	ENSMUST00000210078.2	Cd37 Links Ensembl NCBI MGI UniProt Show fit	CD37 antigen
chr16_+_36755338 Show fit	11.84	ENSMUST00000023531.15	Hcls1 Links Ensembl NCBI MGI UniProt Show fit	hematopoietic cell specific Lyn substrate 1
chr19_+_6449887 Show fit	11.82	ENSMUST00000146601.8 ENSMUST00000150713.8	Rasgrp2 Links Ensembl NCBI MGI UniProt Show fit	RAS, guanyl releasing protein 2
chr2_-_181335767 Show fit	11.73	ENSMUST00000002532.9	Rgs19 Links Ensembl NCBI MGI UniProt Show fit	regulator of G-protein signaling 19
chr2_-_181335518 Show fit	11.68	ENSMUST00000108776.8 ENSMUST00000108771.2	Rgs19 Links Ensembl NCBI MGI UniProt Show fit	regulator of G-protein signaling 19
chr1_+_87548026 Show fit	11.37	ENSMUST00000169754.8 ENSMUST00000042275.15 ENSMUST00000168783.8	Inpp5d Links Ensembl NCBI MGI UniProt Show fit	inositol polyphosphate-5-phosphatase D
chr19_+_6135013 Show fit	11.35	ENSMUST00000025704.3	Cdca5 Links Ensembl NCBI MGI UniProt Show fit	cell division cycle associated 5
chr7_-_3723381 Show fit	10.87	ENSMUST00000078451.7	Pirb Links Ensembl NCBI MGI UniProt Show fit	paired Ig-like receptor B
chr12_-_28685849 Show fit	10.84	ENSMUST00000221871.2	Rps7 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S7
chr17_+_48539782 Show fit	10.79	ENSMUST00000113251.10 ENSMUST00000048782.7	Trem1 Links Ensembl NCBI MGI UniProt Show fit	triggering receptor expressed on myeloid cells 1
chr2_+_91480460 Show fit	10.78	ENSMUST00000111331.9	Arhgap1 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 1
chr16_-_36486429 Show fit	10.64	ENSMUST00000089620.11	Cd86 Links Ensembl NCBI MGI UniProt Show fit	CD86 antigen
chr9_+_106080307 Show fit	10.47	ENSMUST00000024047.12 ENSMUST00000216348.2	Twf2 Links Ensembl NCBI MGI UniProt Show fit	twinfilin actin binding protein 2
chr12_+_105996961 Show fit	10.34	ENSMUST00000220629.2	Vrk1 Links Ensembl NCBI MGI UniProt Show fit	vaccinia related kinase 1
chr8_-_89362745 Show fit	10.11	ENSMUST00000034087.9	Snx20 Links Ensembl NCBI MGI UniProt Show fit	sorting nexin 20
chr12_-_28685913 Show fit	9.76	ENSMUST00000074267.5	Rps7 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S7
chr7_+_3339077 Show fit	9.56	ENSMUST00000203566.3	Myadm Links Ensembl NCBI MGI UniProt Show fit	myeloid-associated differentiation marker
chrX_+_20570145 Show fit	9.55	ENSMUST00000033383.3	Usp11 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 11
chr3_-_59118293 Show fit	9.38	ENSMUST00000040622.3	P2ry13 Links Ensembl NCBI MGI UniProt Show fit	purinergic receptor P2Y, G-protein coupled 13
chr7_+_3339059 Show fit	9.32	ENSMUST00000096744.8	Myadm Links Ensembl NCBI MGI UniProt Show fit	myeloid-associated differentiation marker
chr12_-_79027531 Show fit	9.31	ENSMUST00000174072.8	Tmem229b Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 229B
chr1_-_170755109 Show fit	9.30	ENSMUST00000162136.2 ENSMUST00000162887.2	Fcrla Links Ensembl NCBI MGI UniProt Show fit	Fc receptor-like A
chr1_+_171509565 Show fit	9.26	ENSMUST00000015499.14 ENSMUST00000068584.7	Cd48 Links Ensembl NCBI MGI UniProt Show fit	CD48 antigen
chr2_+_90927053 Show fit	9.26	ENSMUST00000132741.3	Spi1 Links Ensembl NCBI MGI UniProt Show fit	spleen focus forming virus (SFFV) proviral integration oncogene
chr4_+_119052476 Show fit	9.19	ENSMUST00000030395.9	Svbp Links Ensembl NCBI MGI UniProt Show fit	small vasohibin binding protein
chr19_+_10582920 Show fit	9.18	ENSMUST00000236280.2	Ddb1 Links Ensembl NCBI MGI UniProt Show fit	damage specific DNA binding protein 1
chrX_+_141464722 Show fit	9.07	ENSMUST00000112896.9	Tmem164 Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 164
chr2_+_91480513 Show fit	9.04	ENSMUST00000090614.11	Arhgap1 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 1
chr11_+_46701619 Show fit	8.94	ENSMUST00000068877.7	Timd4 Links Ensembl NCBI MGI UniProt Show fit	T cell immunoglobulin and mucin domain containing 4
chr10_-_81360059 Show fit	8.89	ENSMUST00000043709.8	Gna15 Links Ensembl NCBI MGI UniProt Show fit	guanine nucleotide binding protein, alpha 15
chr4_-_115980813 Show fit	8.77	ENSMUST00000102704.4 ENSMUST00000102705.10	Rad54l Links Ensembl NCBI MGI UniProt Show fit	RAD54 like (S. cerevisiae)
chr17_+_34823236 Show fit	8.68	ENSMUST00000174041.8	Agpat1 Links Ensembl NCBI MGI UniProt Show fit	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr3_-_96201248 Show fit	8.58	ENSMUST00000029748.8	Fcgr1 Links Ensembl NCBI MGI UniProt Show fit	Fc receptor, IgG, high affinity I
chr7_+_126808016 Show fit	8.57	ENSMUST00000206204.2 ENSMUST00000206772.2	Mylpf Links Ensembl NCBI MGI UniProt Show fit	myosin light chain, phosphorylatable, fast skeletal muscle
chr4_+_109200225 Show fit	8.48	ENSMUST00000030281.12	Eps15 Links Ensembl NCBI MGI UniProt Show fit	epidermal growth factor receptor pathway substrate 15
chr11_+_117006020 Show fit	8.45	ENSMUST00000103026.10 ENSMUST00000090433.6	Sec14l1 Links Ensembl NCBI MGI UniProt Show fit	SEC14-like lipid binding 1
chr7_-_99132843 Show fit	8.43	ENSMUST00000208532.2 ENSMUST00000107096.2 ENSMUST00000032998.13	Rps3 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S3
chr18_+_75133519 Show fit	8.37	ENSMUST00000079716.6	Rpl17 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein L17
chr6_-_83302890 Show fit	8.33	ENSMUST00000204472.2	Mthfd2 Links Ensembl NCBI MGI UniProt Show fit	methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr5_-_116162415 Show fit	8.07	ENSMUST00000031486.14 ENSMUST00000111999.8	Prkab1 Links Ensembl NCBI MGI UniProt Show fit	protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr7_-_28931873 Show fit	8.06	ENSMUST00000085818.6	Kcnk6 Links Ensembl NCBI MGI UniProt Show fit	potassium inwardly-rectifying channel, subfamily K, member 6
chr9_+_21437440 Show fit	8.04	ENSMUST00000086361.12 ENSMUST00000173769.3	AB124611 Links Ensembl NCBI MGI UniProt Show fit	cDNA sequence AB124611
chr2_+_24276616 Show fit	8.02	ENSMUST00000166388.2	Psd4 Links Ensembl NCBI MGI UniProt Show fit	pleckstrin and Sec7 domain containing 4
chr10_+_81229443 Show fit	7.98	ENSMUST00000118206.2	Smim24 Links Ensembl NCBI MGI UniProt Show fit	small integral membrane protein 24
chr3_-_105839980 Show fit	7.93	ENSMUST00000098758.5	I830077J02Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA I830077J02 gene
chr2_+_120294046 Show fit	7.76	ENSMUST00000028749.15 ENSMUST00000110721.9 ENSMUST00000239364.2	Capn3 Links Ensembl NCBI MGI UniProt Show fit	calpain 3
chr7_+_43057611 Show fit	7.76	ENSMUST00000005592.7	Siglecg Links Ensembl NCBI MGI UniProt Show fit	sialic acid binding Ig-like lectin G
chr13_+_30933209 Show fit	7.72	ENSMUST00000021784.10 ENSMUST00000110307.3 ENSMUST00000222125.2	Irf4 Links Ensembl NCBI MGI UniProt Show fit	interferon regulatory factor 4
chr11_+_87628356 Show fit	7.40	ENSMUST00000093955.12	Supt4a Links Ensembl NCBI MGI UniProt Show fit	SPT4A, DSIF elongation factor subunit
chr19_+_6449776 Show fit	7.36	ENSMUST00000113468.8	Rasgrp2 Links Ensembl NCBI MGI UniProt Show fit	RAS, guanyl releasing protein 2
chr4_+_119052693 Show fit	7.36	ENSMUST00000097908.4	Svbp Links Ensembl NCBI MGI UniProt Show fit	small vasohibin binding protein
chr19_+_10582987 Show fit	7.24	ENSMUST00000237337.2	Ddb1 Links Ensembl NCBI MGI UniProt Show fit	damage specific DNA binding protein 1
chr17_+_8144822 Show fit	7.18	ENSMUST00000036370.8	Tagap Links Ensembl NCBI MGI UniProt Show fit	T cell activation Rho GTPase activating protein
chr10_+_81093110 Show fit	7.13	ENSMUST00000117488.8 ENSMUST00000105328.10 ENSMUST00000121205.8	Matk Links Ensembl NCBI MGI UniProt Show fit	megakaryocyte-associated tyrosine kinase
chr7_-_100505486 Show fit	7.07	ENSMUST00000139604.8	Relt Links Ensembl NCBI MGI UniProt Show fit	RELT tumor necrosis factor receptor
chr1_+_171594690 Show fit	6.88	ENSMUST00000015460.5	Slamf1 Links Ensembl NCBI MGI UniProt Show fit	signaling lymphocytic activation molecule family member 1
chr11_-_115024807 Show fit	6.84	ENSMUST00000106561.8 ENSMUST00000051264.14 ENSMUST00000106562.3	Cd300lf Links Ensembl NCBI MGI UniProt Show fit	CD300 molecule like family member F
chr17_-_35827676 Show fit	6.78	ENSMUST00000160885.2 ENSMUST00000159009.2 ENSMUST00000161012.8	Tcf19 Links Ensembl NCBI MGI UniProt Show fit	transcription factor 19
chr17_+_36179273 Show fit	6.75	ENSMUST00000190496.2	Ppp1r18 Links Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory subunit 18
chr9_-_114811807 Show fit	6.70	ENSMUST00000053150.8	Rps27rt Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S27, retrogene
chr13_+_104365432 Show fit	6.69	ENSMUST00000070761.10 ENSMUST00000225557.2	Cenpk Links Ensembl NCBI MGI UniProt Show fit	centromere protein K
chr11_-_97673203 Show fit	6.68	ENSMUST00000128801.2 ENSMUST00000103146.5	Rpl23 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein L23
chr10_-_88192852 Show fit	6.54	ENSMUST00000020249.2	Dram1 Links Ensembl NCBI MGI UniProt Show fit	DNA-damage regulated autophagy modulator 1
chr2_+_25313240 Show fit	6.42	ENSMUST00000134259.8 ENSMUST00000100320.5	Fut7 Links Ensembl NCBI MGI UniProt Show fit	fucosyltransferase 7
chr9_+_64718596 Show fit	6.40	ENSMUST00000038890.6	Dennd4a Links Ensembl NCBI MGI UniProt Show fit	DENN/MADD domain containing 4A
chr4_+_119052548 Show fit	6.32	ENSMUST00000106345.3	Svbp Links Ensembl NCBI MGI UniProt Show fit	small vasohibin binding protein
chr4_+_132903646 Show fit	6.27	ENSMUST00000105912.2	Wasf2 Links Ensembl NCBI MGI UniProt Show fit	WASP family, member 2
chr7_-_80994933 Show fit	6.15	ENSMUST00000080813.5	Rps17 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S17
chr8_+_72943455 Show fit	6.11	ENSMUST00000072097.14	Hsh2d Links Ensembl NCBI MGI UniProt Show fit	hematopoietic SH2 domain containing
chr2_+_32611067 Show fit	6.11	ENSMUST00000074248.11	Sh2d3c Links Ensembl NCBI MGI UniProt Show fit	SH2 domain containing 3C
chr11_+_70021155 Show fit	6.10	ENSMUST00000041550.12 ENSMUST00000165951.8	Mgl2 Links Ensembl NCBI MGI UniProt Show fit	macrophage galactose N-acetyl-galactosamine specific lectin 2
chr6_-_124710030 Show fit	6.09	ENSMUST00000173647.2	Ptpn6 Links Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, non-receptor type 6
chr2_+_163916042 Show fit	5.91	ENSMUST00000018353.14	Stk4 Links Ensembl NCBI MGI UniProt Show fit	serine/threonine kinase 4
chr13_-_13568106 Show fit	5.81	ENSMUST00000021738.10 ENSMUST00000220628.2	Gpr137b Links Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 137B
chr4_-_136620376 Show fit	5.80	ENSMUST00000046332.6	C1qc Links Ensembl NCBI MGI UniProt Show fit	complement component 1, q subcomponent, C chain
chr12_+_98234884 Show fit	5.74	ENSMUST00000075072.6	Gpr65 Links Ensembl NCBI MGI UniProt Show fit	G-protein coupled receptor 65
chr6_+_122929591 Show fit	5.69	ENSMUST00000088468.7	Clec4a3 Links Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 4, member a3
chr4_-_136613498 Show fit	5.68	ENSMUST00000046384.9	C1qb Links Ensembl NCBI MGI UniProt Show fit	complement component 1, q subcomponent, beta polypeptide
chr8_-_25592385 Show fit	5.60	ENSMUST00000064883.14	Plekha2 Links Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr19_+_6108240 Show fit	5.38	ENSMUST00000237840.2	Fau Links Ensembl NCBI MGI UniProt Show fit	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr10_-_40178182 Show fit	5.38	ENSMUST00000099945.6 ENSMUST00000238953.2 ENSMUST00000238969.2	Amd1 Links Ensembl NCBI MGI UniProt Show fit	S-adenosylmethionine decarboxylase 1
chr4_-_117232650 Show fit	5.30	ENSMUST00000094853.9	Rnf220 Links Ensembl NCBI MGI UniProt Show fit	ring finger protein 220
chr4_-_141602190 Show fit	5.30	ENSMUST00000036854.4	Efhd2 Links Ensembl NCBI MGI UniProt Show fit	EF hand domain containing 2
chr1_-_125362321 Show fit	5.25	ENSMUST00000191544.7	Actr3 Links Ensembl NCBI MGI UniProt Show fit	ARP3 actin-related protein 3
chr15_+_97259060 Show fit	5.23	ENSMUST00000228521.2 ENSMUST00000226495.2	Pced1b Links Ensembl NCBI MGI UniProt Show fit	PC-esterase domain containing 1B
chr8_-_123302187 Show fit	5.08	ENSMUST00000213062.2	Aprt Links Ensembl NCBI MGI UniProt Show fit	adenine phosphoribosyl transferase
chrX_+_41238193 Show fit	5.08	ENSMUST00000115073.9 ENSMUST00000115072.8	Stag2 Links Ensembl NCBI MGI UniProt Show fit	stromal antigen 2
chr19_+_6107874 Show fit	5.02	ENSMUST00000178310.9	Fau Links Ensembl NCBI MGI UniProt Show fit	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr6_-_124710084 Show fit	4.97	ENSMUST00000112484.10	Ptpn6 Links Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, non-receptor type 6
chr15_+_80832685 Show fit	4.96	ENSMUST00000023043.10 ENSMUST00000164806.6 ENSMUST00000207170.2 ENSMUST00000168756.8	Adsl Links Ensembl NCBI MGI UniProt Show fit	adenylosuccinate lyase
chr19_+_6107957 Show fit	4.89	ENSMUST00000237859.2 ENSMUST00000043074.14 ENSMUST00000236336.2 ENSMUST00000179142.2 ENSMUST00000236217.2	Fau Links Ensembl NCBI MGI UniProt Show fit	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr7_-_3848050 Show fit	4.85	ENSMUST00000108615.10 ENSMUST00000119469.2	Pira2 Links Ensembl NCBI MGI UniProt Show fit	paired-Ig-like receptor A2
chr7_-_126807581 Show fit	4.83	ENSMUST00000120705.3	Tbc1d10b Links Ensembl NCBI MGI UniProt Show fit	TBC1 domain family, member 10b
chr2_+_43638814 Show fit	4.81	ENSMUST00000112824.8 ENSMUST00000055776.8	Arhgap15 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 15
chr13_-_23650045 Show fit	4.75	ENSMUST00000041674.14 ENSMUST00000110434.2	Btn1a1 Links Ensembl NCBI MGI UniProt Show fit	butyrophilin, subfamily 1, member A1
chr14_+_75368939 Show fit	4.61	ENSMUST00000125833.8 ENSMUST00000124499.8	Lcp1 Links Ensembl NCBI MGI UniProt Show fit	lymphocyte cytosolic protein 1
chr8_+_79754980 Show fit	4.55	ENSMUST00000087927.11 ENSMUST00000098614.9	Zfp827 Links Ensembl NCBI MGI UniProt Show fit	zinc finger protein 827
chr8_+_121215155 Show fit	4.37	ENSMUST00000034279.16	Gse1 Links Ensembl NCBI MGI UniProt Show fit	genetic suppressor element 1, coiled-coil protein
chr19_-_11313471 Show fit	4.34	ENSMUST00000056035.9 ENSMUST00000067532.11	Ms4a7 Links Ensembl NCBI MGI UniProt Show fit	membrane-spanning 4-domains, subfamily A, member 7
chr1_-_38704028 Show fit	4.29	ENSMUST00000039827.14	Aff3 Links Ensembl NCBI MGI UniProt Show fit	AF4/FMR2 family, member 3
chr4_+_124608569 Show fit	4.27	ENSMUST00000030734.5	Sf3a3 Links Ensembl NCBI MGI UniProt Show fit	splicing factor 3a, subunit 3
chr8_+_95472218 Show fit	4.24	ENSMUST00000034231.4	Ccl22 Links Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) ligand 22
chr11_+_120348919 Show fit	4.10	ENSMUST00000058370.14 ENSMUST00000175970.8 ENSMUST00000176120.2	Ccdc137 Links Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 137
chr6_+_60921456 Show fit	4.09	ENSMUST00000129603.4 ENSMUST00000204333.2	Mmrn1 Links Ensembl NCBI MGI UniProt Show fit	multimerin 1
chr4_-_135780660 Show fit	4.03	ENSMUST00000102536.11	Rpl11 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein L11
chr3_-_89959770 Show fit	4.02	ENSMUST00000029553.16 ENSMUST00000195995.5 ENSMUST00000064639.15 ENSMUST00000199834.5	Ubap2l Links Ensembl NCBI MGI UniProt Show fit	ubiquitin-associated protein 2-like
chr10_-_6930376 Show fit	3.92	ENSMUST00000105617.8	Ipcef1 Links Ensembl NCBI MGI UniProt Show fit	interaction protein for cytohesin exchange factors 1
chr14_-_66071412 Show fit	3.86	ENSMUST00000022613.10	Esco2 Links Ensembl NCBI MGI UniProt Show fit	establishment of sister chromatid cohesion N-acetyltransferase 2
chr11_-_115590318 Show fit	3.85	ENSMUST00000106497.8	Grb2 Links Ensembl NCBI MGI UniProt Show fit	growth factor receptor bound protein 2
chr7_+_101520843 Show fit	3.84	ENSMUST00000210984.2	Anapc15 Links Ensembl NCBI MGI UniProt Show fit	anaphase promoting complex C subunit 15
chrX_+_7656225 Show fit	3.79	ENSMUST00000136930.8 ENSMUST00000115675.9 ENSMUST00000101694.10	Gripap1 Links Ensembl NCBI MGI UniProt Show fit	GRIP1 associated protein 1
chr7_+_127078371 Show fit	3.75	ENSMUST00000205432.3	Fbrs Links Ensembl NCBI MGI UniProt Show fit	fibrosin
chr6_-_120799500 Show fit	3.67	ENSMUST00000204699.2	Atp6v1e1 Links Ensembl NCBI MGI UniProt Show fit	ATPase, H+ transporting, lysosomal V1 subunit E1
chr3_-_89959739 Show fit	3.60	ENSMUST00000199929.2 ENSMUST00000090908.11 ENSMUST00000198322.5 ENSMUST00000196843.5	Ubap2l Links Ensembl NCBI MGI UniProt Show fit	ubiquitin-associated protein 2-like
chr5_+_86219593 Show fit	3.60	ENSMUST00000198435.5 ENSMUST00000031171.9	Stap1 Links Ensembl NCBI MGI UniProt Show fit	signal transducing adaptor family member 1
chr2_-_91480096 Show fit	3.52	ENSMUST00000099714.10 ENSMUST00000111333.2	Zfp408 Links Ensembl NCBI MGI UniProt Show fit	zinc finger protein 408
chr19_-_40982576 Show fit	3.50	ENSMUST00000117695.8	Blnk Links Ensembl NCBI MGI UniProt Show fit	B cell linker
chr8_-_25730878 Show fit	3.44	ENSMUST00000210488.2 ENSMUST00000210933.2	Tacc1 Links Ensembl NCBI MGI UniProt Show fit	transforming, acidic coiled-coil containing protein 1
chr3_-_135313982 Show fit	3.44	ENSMUST00000132668.8	Nfkb1 Links Ensembl NCBI MGI UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr18_-_43610829 Show fit	3.43	ENSMUST00000057110.11	Eif3j2 Links Ensembl NCBI MGI UniProt Show fit	eukaryotic translation initiation factor 3, subunit J2
chr7_-_46658144 Show fit	3.42	ENSMUST00000061639.10	Spty2d1 Links Ensembl NCBI MGI UniProt Show fit	SPT2 chromatin protein domain containing 1
chr17_-_50497682 Show fit	3.30	ENSMUST00000044503.14	Rftn1 Links Ensembl NCBI MGI UniProt Show fit	raftlin lipid raft linker 1
chr9_+_123902143 Show fit	3.30	ENSMUST00000168841.3 ENSMUST00000055918.7	Ccr2 Links Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) receptor 2
chr19_-_5711650 Show fit	3.26	ENSMUST00000236006.2	Sipa1 Links Ensembl NCBI MGI UniProt Show fit	signal-induced proliferation associated gene 1
chr6_+_83303052 Show fit	3.26	ENSMUST00000038658.15	Mob1a Links Ensembl NCBI MGI UniProt Show fit	MOB kinase activator 1A
chr14_-_65830463 Show fit	3.23	ENSMUST00000225355.2 ENSMUST00000022609.7	Elp3 Links Ensembl NCBI MGI UniProt Show fit	elongator acetyltransferase complex subunit 3
chr4_-_92079986 Show fit	3.20	ENSMUST00000123179.2	Gm12666 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 12666
chr9_+_64718708 Show fit	3.18	ENSMUST00000213926.2	Dennd4a Links Ensembl NCBI MGI UniProt Show fit	DENN/MADD domain containing 4A
chr2_-_60793536 Show fit	3.16	ENSMUST00000028347.13	Rbms1 Links Ensembl NCBI MGI UniProt Show fit	RNA binding motif, single stranded interacting protein 1
chr3_+_60380463 Show fit	3.15	ENSMUST00000195077.6 ENSMUST00000193647.6 ENSMUST00000195001.2 ENSMUST00000192807.6	Mbnl1 Links Ensembl NCBI MGI UniProt Show fit	muscleblind like splicing factor 1
chr7_+_127187910 Show fit	3.09	ENSMUST00000205694.2 ENSMUST00000033088.8 ENSMUST00000206914.2	Rnf40 Links Ensembl NCBI MGI UniProt Show fit	ring finger protein 40
chr14_-_30645711 Show fit	3.08	ENSMUST00000006697.17	Itih3 Links Ensembl NCBI MGI UniProt Show fit	inter-alpha trypsin inhibitor, heavy chain 3
chr5_+_115680964 Show fit	3.05	ENSMUST00000137716.8	Pxn Links Ensembl NCBI MGI UniProt Show fit	paxillin
chr11_+_113548201 Show fit	3.04	ENSMUST00000148736.8 ENSMUST00000142069.8 ENSMUST00000134418.8	Cog1 Links Ensembl NCBI MGI UniProt Show fit	component of oligomeric golgi complex 1
chr16_-_89757693 Show fit	2.98	ENSMUST00000002588.11	Tiam1 Links Ensembl NCBI MGI UniProt Show fit	T cell lymphoma invasion and metastasis 1
chr10_+_96453408 Show fit	2.93	ENSMUST00000218953.2	Btg1 Links Ensembl NCBI MGI UniProt Show fit	BTG anti-proliferation factor 1
chrX_-_93166992 Show fit	2.92	ENSMUST00000088102.12 ENSMUST00000113927.8	Zfx Links Ensembl NCBI MGI UniProt Show fit	zinc finger protein X-linked
chr5_-_140368482 Show fit	2.90	ENSMUST00000196566.5	Snx8 Links Ensembl NCBI MGI UniProt Show fit	sorting nexin 8
chr13_+_102830029 Show fit	2.90	ENSMUST00000022124.10 ENSMUST00000171267.2 ENSMUST00000167144.2 ENSMUST00000170878.2	Cd180 Links Ensembl NCBI MGI UniProt Show fit	CD180 antigen
chr1_+_75498162 Show fit	2.90	ENSMUST00000027414.16 ENSMUST00000113553.2	Stk11ip Links Ensembl NCBI MGI UniProt Show fit	serine/threonine kinase 11 interacting protein
chr6_+_83302998 Show fit	2.89	ENSMUST00000055261.11	Mob1a Links Ensembl NCBI MGI UniProt Show fit	MOB kinase activator 1A
chr5_+_123280250 Show fit	2.83	ENSMUST00000174836.8 ENSMUST00000163030.9	Setd1b Links Ensembl NCBI MGI UniProt Show fit	SET domain containing 1B
chr9_+_106099797 Show fit	2.80	ENSMUST00000062241.11	Tlr9 Links Ensembl NCBI MGI UniProt Show fit	toll-like receptor 9
chr11_-_115590133 Show fit	2.78	ENSMUST00000106499.8	Grb2 Links Ensembl NCBI MGI UniProt Show fit	growth factor receptor bound protein 2
chr12_-_32258331 Show fit	2.76	ENSMUST00000220366.2	Pik3cg Links Ensembl NCBI MGI UniProt Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr2_-_91795910 Show fit	2.74	ENSMUST00000239257.2	Dgkz Links Ensembl NCBI MGI UniProt Show fit	diacylglycerol kinase zeta
chrX_+_168468186 Show fit	2.74	ENSMUST00000112107.8 ENSMUST00000112104.8	Mid1 Links Ensembl NCBI MGI UniProt Show fit	midline 1

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.1	27.3	GO:0001788	antibody-dependent cellular cytotoxicity(GO:0001788)
8.5	51.0	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
7.9	23.6	GO:0002277	myeloid dendritic cell activation involved in immune response(GO:0002277)
7.8	23.3	GO:0060305	regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010924) positive regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010925) phospholipase C-inhibiting G-protein coupled receptor signaling pathway(GO:0030845) regulation of cell diameter(GO:0060305)
7.7	23.1	GO:0070947	neutrophil mediated killing of fungus(GO:0070947)
6.9	55.1	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
6.8	20.5	GO:0045660	positive regulation of neutrophil differentiation(GO:0045660)
6.8	61.0	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
5.6	33.5	GO:0070560	calcium-mediated signaling using extracellular calcium source(GO:0035585) protein secretion by platelet(GO:0070560)
5.1	15.3	GO:0072356	chromosome passenger complex localization to kinetochore(GO:0072356)
4.6	13.7	GO:0001805	type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
4.3	47.3	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
4.0	16.2	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
3.7	14.9	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
3.6	18.1	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
3.4	10.3	GO:0072355	histone H3-T3 phosphorylation(GO:0072355)
3.3	19.8	GO:0032439	endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336)
2.8	11.4	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
2.7	16.4	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
2.6	20.9	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
2.6	7.7	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
2.4	9.8	GO:0002337	B-1a B cell differentiation(GO:0002337)
2.4	16.8	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
2.4	18.9	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
2.3	16.2	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
2.3	11.4	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
2.1	8.4	GO:1905053	regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
2.0	31.3	GO:1904667	negative regulation of ubiquitin protein ligase activity(GO:1904667)
1.9	7.8	GO:1990091	sodium-dependent self proteolysis(GO:1990091)
1.9	9.3	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
1.8	55.9	GO:0032060	bleb assembly(GO:0032060)
1.8	3.6	GO:1903972	regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
1.8	5.4	GO:0006597	spermine biosynthetic process(GO:0006597)
1.7	6.8	GO:0035963	TRIF-dependent toll-like receptor signaling pathway(GO:0035666) interleukin-4-mediated signaling pathway(GO:0035771) response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) negative regulation of apoptotic cell clearance(GO:2000426)
1.6	15.9	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
1.5	10.8	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
1.5	15.2	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
1.5	5.9	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.5	14.5	GO:0032074	negative regulation of nuclease activity(GO:0032074)
1.4	11.1	GO:0033277	abortive mitotic cell cycle(GO:0033277)
1.3	8.1	GO:0060075	regulation of resting membrane potential(GO:0060075)
1.3	5.1	GO:0046083	adenine salvage(GO:0006168) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
1.2	5.0	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
1.2	8.5	GO:0015871	choline transport(GO:0015871)
1.1	3.4	GO:1904629	negative regulation of interleukin-12 biosynthetic process(GO:0045083) response to diterpene(GO:1904629) cellular response to diterpene(GO:1904630) response to glucoside(GO:1904631) cellular response to glucoside(GO:1904632)
1.1	4.6	GO:0071477	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
1.1	8.9	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
1.0	10.5	GO:0032532	regulation of microvillus length(GO:0032532)
1.0	15.3	GO:0002227	innate immune response in mucosa(GO:0002227)
1.0	6.1	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
1.0	13.0	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.0	3.0	GO:1990751	regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
1.0	3.0	GO:1903977	immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of glial cell migration(GO:1903977) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.9	2.8	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
0.9	7.5	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.9	10.7	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
0.9	8.8	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.9	15.7	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.9	3.4	GO:0010847	regulation of chromatin assembly(GO:0010847)
0.8	8.5	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.7	5.8	GO:0045649	regulation of macrophage differentiation(GO:0045649) negative regulation of macrophage differentiation(GO:0045650)
0.7	6.2	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
0.7	3.3	GO:0042631	cellular response to water deprivation(GO:0042631)
0.6	2.6	GO:0001928	regulation of exocyst assembly(GO:0001928)
0.6	3.7	GO:2001168	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.6	7.4	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.6	13.9	GO:0034138	toll-like receptor 3 signaling pathway(GO:0034138)
0.6	36.2	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.6	1.8	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.6	1.7	GO:0043686	co-translational protein modification(GO:0043686)
0.6	8.4	GO:0036065	fucosylation(GO:0036065)
0.5	2.7	GO:0034421	post-translational protein acetylation(GO:0034421)
0.5	1.6	GO:2000019	negative regulation of male gonad development(GO:2000019)
0.5	2.1	GO:0033379	protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.5	1.0	GO:0001812	positive regulation of type I hypersensitivity(GO:0001812)
0.5	1.5	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.5	1.5	GO:0051659	maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
0.4	18.0	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.4	1.6	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.4	2.4	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.4	8.8	GO:0008340	determination of adult lifespan(GO:0008340)
0.4	2.2	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3	6.6	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3	21.8	GO:0010596	negative regulation of endothelial cell migration(GO:0010596)
0.3	7.4	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.3	2.9	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.3	9.4	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.3	5.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.3	6.3	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.3	1.8	GO:2000354	negative regulation of immature T cell proliferation(GO:0033087) regulation of ovarian follicle development(GO:2000354)
0.3	3.8	GO:0070572	positive regulation of neuron projection regeneration(GO:0070572)
0.3	27.7	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.3	8.3	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.3	3.0	GO:0035878	nail development(GO:0035878)
0.3	3.8	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.3	2.5	GO:0060762	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) germline stem cell asymmetric division(GO:0098728)
0.3	0.8	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.3	4.6	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.3	2.1	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3	19.2	GO:0071277	cellular response to calcium ion(GO:0071277)
0.3	9.3	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2	1.9	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.2	1.2	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2	2.4	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.2	2.9	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.2	4.6	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.2	1.5	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.2	6.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.2	6.8	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
0.2	14.9	GO:1902476	chloride transmembrane transport(GO:1902476)
0.2	1.0	GO:0032918	polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2	2.7	GO:0035372	protein localization to microtubule(GO:0035372)
0.2	72.2	GO:0019221	cytokine-mediated signaling pathway(GO:0019221)
0.2	1.4	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.2	5.7	GO:0010447	response to acidic pH(GO:0010447)
0.2	0.5	GO:1903027	regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1	0.6	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	2.0	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.1	4.9	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1	3.4	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	2.1	GO:0031507	heterochromatin assembly(GO:0031507)
0.1	2.3	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.1	23.2	GO:0000910	cytokinesis(GO:0000910)
0.1	6.2	GO:0035329	hippo signaling(GO:0035329)
0.1	2.0	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1	0.5	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.1	23.8	GO:1990823	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1	3.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	13.1	GO:0044264	cellular polysaccharide metabolic process(GO:0044264)
0.1	2.1	GO:0006744	ubiquinone biosynthetic process(GO:0006744)
0.1	2.4	GO:0006903	vesicle targeting(GO:0006903)
0.1	1.1	GO:0070933	histone H4 deacetylation(GO:0070933)
0.1	23.0	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.1	3.1	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991)
0.1	0.8	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.1	3.0	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.1	3.7	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1	9.6	GO:0016579	protein deubiquitination(GO:0016579)
0.1	3.5	GO:0034612	response to tumor necrosis factor(GO:0034612)
0.1	1.6	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1	1.4	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	0.2	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	0.8	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.0	3.4	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	0.2	GO:0002266	follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.0	3.7	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.3	GO:0034214	protein hexamerization(GO:0034214)
0.0	5.7	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.4	GO:0032484	Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0	0.1	GO:1903538	meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0	0.9	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	1.1	GO:0045761	regulation of adenylate cyclase activity(GO:0045761)
0.0	0.2	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.7	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.9	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.7	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.8	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	1.2	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	1.0	GO:0032091	negative regulation of protein binding(GO:0032091)
0.0	0.1	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.0	GO:0035696	monocyte extravasation(GO:0035696)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.8	33.5	GO:0031095	platelet dense tubular network membrane(GO:0031095)
4.6	13.7	GO:0032997	Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
2.9	22.8	GO:0005826	actomyosin contractile ring(GO:0005826)
2.8	19.8	GO:0097443	sorting endosome(GO:0097443)
2.3	16.4	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
2.1	53.4	GO:0032426	stereocilium tip(GO:0032426)
1.8	9.1	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.5	23.1	GO:0043020	NADPH oxidase complex(GO:0043020)
1.4	21.2	GO:0031209	SCAR complex(GO:0031209)
1.4	34.4	GO:0042581	specific granule(GO:0042581)
1.2	23.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
1.0	20.9	GO:0031143	pseudopodium(GO:0031143)
0.9	11.4	GO:0008278	cohesin complex(GO:0008278)
0.9	42.6	GO:0001772	immunological synapse(GO:0001772)
0.9	11.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.8	16.8	GO:0042101	T cell receptor complex(GO:0042101)
0.8	50.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.8	2.4	GO:0043614	multi-eIF complex(GO:0043614)
0.8	6.2	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.7	6.6	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.7	15.3	GO:1990023	mitotic spindle midzone(GO:1990023)
0.6	16.2	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.5	6.0	GO:0000788	nuclear nucleosome(GO:0000788)
0.5	2.8	GO:0036019	endolysosome(GO:0036019)
0.5	3.7	GO:0033503	HULC complex(GO:0033503)
0.5	2.3	GO:0034684	integrin alphav-beta5 complex(GO:0034684)
0.5	3.2	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.5	1.4	GO:0098843	postsynaptic endocytic zone(GO:0098843)
0.4	32.0	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.4	8.5	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.4	44.7	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.4	10.3	GO:0005795	Golgi stack(GO:0005795)
0.3	6.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.3	4.9	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.3	3.0	GO:0060091	kinocilium(GO:0060091)
0.3	8.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.3	3.6	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.3	34.8	GO:0032587	ruffle membrane(GO:0032587)
0.2	12.6	GO:0031901	early endosome membrane(GO:0031901)
0.2	1.8	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2	10.5	GO:0032420	stereocilium(GO:0032420)
0.2	21.4	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.2	3.0	GO:0017119	Golgi transport complex(GO:0017119)
0.2	14.9	GO:0034707	chloride channel complex(GO:0034707)
0.2	36.6	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2	2.1	GO:0042629	mast cell granule(GO:0042629)
0.2	11.4	GO:0030863	cortical cytoskeleton(GO:0030863)
0.2	1.5	GO:0031673	H zone(GO:0031673)
0.2	2.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.2	4.6	GO:0002102	podosome(GO:0002102)
0.2	2.2	GO:0016342	catenin complex(GO:0016342)
0.1	1.7	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	2.0	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	9.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	1.4	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.1	3.8	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	43.6	GO:0031965	nuclear membrane(GO:0031965)
0.1	7.4	GO:0008023	transcription elongation factor complex(GO:0008023)
0.1	28.0	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1	8.8	GO:0031519	PcG protein complex(GO:0031519)
0.1	13.9	GO:0045177	apical part of cell(GO:0045177)
0.1	2.6	GO:0000145	exocyst(GO:0000145)
0.1	0.5	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.1	11.5	GO:0005581	collagen trimer(GO:0005581)
0.1	4.9	GO:0045335	phagocytic vesicle(GO:0045335)
0.1	1.6	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	1.7	GO:0071004	U2-type prespliceosome(GO:0071004)
0.1	7.8	GO:0030315	T-tubule(GO:0030315)
0.1	12.7	GO:0030027	lamellipodium(GO:0030027)
0.1	1.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	1.5	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	2.7	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	1.8	GO:0008180	COP9 signalosome(GO:0008180)
0.0	5.0	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	1.9	GO:0030139	endocytic vesicle(GO:0030139)
0.0	0.9	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.9	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.7	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	12.1	GO:0005768	endosome(GO:0005768)
0.0	1.1	GO:0035861	site of double-strand break(GO:0035861)
0.0	3.6	GO:0000776	kinetochore(GO:0000776)
0.0	13.0	GO:0005911	cell-cell junction(GO:0005911)
0.0	2.0	GO:0030496	midbody(GO:0030496)
0.0	4.1	GO:0001650	fibrillar center(GO:0001650)
0.0	5.5	GO:0000139	Golgi membrane(GO:0000139)
0.0	109.3	GO:0016021	integral component of membrane(GO:0016021)
0.0	0.5	GO:0005903	brush border(GO:0005903)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.2	51.0	GO:0004051	arachidonate 5-lipoxygenase activity(GO:0004051)
7.0	20.9	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
6.8	61.0	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
6.0	18.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
3.5	31.3	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
3.4	10.3	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
2.9	14.7	GO:0019767	IgE receptor activity(GO:0019767)
2.8	8.4	GO:0097100	supercoiled DNA binding(GO:0097100)
2.5	53.4	GO:0032036	myosin heavy chain binding(GO:0032036)
1.8	23.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.7	6.8	GO:0005136	interleukin-4 receptor binding(GO:0005136)
1.7	5.1	GO:0002055	adenine binding(GO:0002055) adenine phosphoribosyltransferase activity(GO:0003999)
1.4	11.4	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312) PTB domain binding(GO:0051425)
1.4	8.4	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
1.4	8.3	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
1.2	5.0	GO:0016842	amidine-lyase activity(GO:0016842)
1.2	3.6	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
1.2	4.6	GO:0051435	BH4 domain binding(GO:0051435)
1.1	4.6	GO:0035827	rubidium ion transmembrane transporter activity(GO:0035827)
1.1	6.4	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.0	36.7	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
1.0	37.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
1.0	3.0	GO:0035717	chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.9	6.4	GO:0019808	polyamine binding(GO:0019808)
0.9	57.0	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.9	11.1	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.8	8.8	GO:0036310	annealing helicase activity(GO:0036310)
0.7	43.4	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.6	3.2	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.6	9.3	GO:0051525	NFAT protein binding(GO:0051525)
0.6	16.4	GO:0097602	cullin family protein binding(GO:0097602)
0.6	7.5	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.6	3.4	GO:0019770	IgG receptor activity(GO:0019770)
0.5	73.5	GO:0004896	cytokine receptor activity(GO:0004896)
0.5	7.8	GO:0031432	titin binding(GO:0031432)
0.5	21.9	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.5	2.8	GO:0045322	unmethylated CpG binding(GO:0045322)
0.4	3.9	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.4	8.1	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.4	33.5	GO:0030507	spectrin binding(GO:0030507)
0.4	1.5	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.4	8.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.3	1.3	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
0.3	6.2	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3	4.9	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.3	2.0	GO:0008417	fucosyltransferase activity(GO:0008417)
0.3	8.9	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.3	20.6	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2	15.7	GO:0016860	intramolecular oxidoreductase activity(GO:0016860)
0.2	8.6	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.2	2.7	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2	8.9	GO:0001786	phosphatidylserine binding(GO:0001786)
0.2	9.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2	45.9	GO:0017124	SH3 domain binding(GO:0017124)
0.2	7.1	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2	2.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.2	1.0	GO:0004111	creatine kinase activity(GO:0004111)
0.2	1.6	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2	9.7	GO:0048365	Rac GTPase binding(GO:0048365)
0.2	1.7	GO:0004579	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2	14.9	GO:0030295	protein kinase activator activity(GO:0030295)
0.2	8.6	GO:0008307	structural constituent of muscle(GO:0008307)
0.2	2.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	1.4	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	10.2	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1	1.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	24.1	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	10.8	GO:0097110	scaffold protein binding(GO:0097110)
0.1	3.5	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	1.4	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	1.5	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1	14.9	GO:0005254	chloride channel activity(GO:0005254)
0.1	22.9	GO:0019903	protein phosphatase binding(GO:0019903)
0.1	15.9	GO:0019887	protein kinase regulator activity(GO:0019887)
0.1	3.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	2.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	1.9	GO:0070300	phosphatidic acid binding(GO:0070300)
0.1	6.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	3.1	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	1.9	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	0.5	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	9.6	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1	2.0	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1	1.6	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.8	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1	6.7	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	3.4	GO:0042805	actinin binding(GO:0042805)
0.1	4.2	GO:0019902	phosphatase binding(GO:0019902)
0.1	5.1	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	27.2	GO:0045296	cadherin binding(GO:0045296)
0.1	13.1	GO:0052689	carboxylic ester hydrolase activity(GO:0052689)
0.1	4.5	GO:0004177	aminopeptidase activity(GO:0004177)
0.1	1.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	2.1	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0	10.5	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.0	7.8	GO:0005125	cytokine activity(GO:0005125)
0.0	0.9	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.7	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	1.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	2.7	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	8.7	GO:0051020	GTPase binding(GO:0051020)
0.0	2.1	GO:0005518	collagen binding(GO:0005518)
0.0	0.3	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.0	0.3	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.2	GO:0009019	tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0	3.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	1.7	GO:0008083	growth factor activity(GO:0008083)
0.0	2.3	GO:0005178	integrin binding(GO:0005178)
0.0	4.1	GO:0042393	histone binding(GO:0042393)
0.0	0.9	GO:0043022	ribosome binding(GO:0043022)
0.0	1.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.3	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	3.3	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.1	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.0	0.8	GO:0004004	RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.5	GO:0043531	ADP binding(GO:0043531)
0.0	2.7	GO:0000287	magnesium ion binding(GO:0000287)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	52.5	PID IL5 PATHWAY	IL5-mediated signaling events
1.1	61.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.8	58.3	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.7	67.1	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.6	23.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.6	57.2	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.5	40.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.5	11.4	PID IL3 PATHWAY	IL3-mediated signaling events
0.4	19.8	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.3	15.3	PID IL12 2PATHWAY	IL12-mediated signaling events
0.3	17.0	PID IL4 2PATHWAY	IL4-mediated signaling events
0.3	12.3	PID ARF6 PATHWAY	Arf6 signaling events
0.2	2.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.2	10.7	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.2	1.8	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.2	14.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2	8.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.2	8.5	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2	8.6	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.2	5.5	PID AURORA A PATHWAY	Aurora A signaling
0.1	14.1	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.1	10.7	PID P53 REGULATION PATHWAY	p53 pathway
0.1	2.7	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	2.6	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	2.4	PID BCR 5PATHWAY	BCR signaling pathway
0.1	2.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	22.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	1.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	1.4	PID ARF 3PATHWAY	Arf1 pathway
0.0	2.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	2.1	PID AURORA B PATHWAY	Aurora B signaling
0.0	2.1	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.7	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	1.0	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	1.9	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.6	PID LKB1 PATHWAY	LKB1 signaling events
0.0	1.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	2.4	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.6	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	4.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.5	PID TNF PATHWAY	TNF receptor signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	34.6	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
1.4	11.5	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
1.4	22.8	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
1.4	29.8	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
1.1	56.9	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
1.0	13.7	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
1.0	19.2	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.9	16.8	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.9	70.6	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.7	25.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.7	57.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.7	16.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.6	8.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.5	8.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.5	2.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.4	32.0	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.4	15.7	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.4	89.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.4	9.9	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.4	6.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.4	12.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	3.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.3	6.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.3	19.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.3	10.0	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.3	4.0	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.3	3.0	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.3	2.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.3	6.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3	5.0	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	22.0	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.2	5.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	9.6	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2	2.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.2	1.8	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.2	3.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	2.6	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	13.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.5	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	1.6	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	1.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	8.7	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.1	0.8	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.1	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	2.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	4.2	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.1	2.0	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	1.6	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.7	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	2.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	2.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	6.0	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	4.7	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	4.9	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.2	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.0	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	1.2	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase