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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Stat1

Z-value: 1.40

Motif logo

Transcription factors associated with Stat1

Gene Symbol Gene ID Gene Info
ENSMUSG00000026104.15 Stat1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Stat1mm39_v1_chr1_+_52158599_521586600.298.6e-02Click!

Activity profile of Stat1 motif

Sorted Z-values of Stat1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_34389269 10.46 ENSMUST00000007449.9
aldo-keto reductase family 1, member B7
chr9_+_110867807 9.76 ENSMUST00000197575.2
lactotransferrin
chr4_+_114916703 5.61 ENSMUST00000162489.2
T cell acute lymphocytic leukemia 1
chr1_+_134110142 5.35 ENSMUST00000082060.10
ENSMUST00000153856.8
ENSMUST00000133701.8
ENSMUST00000132873.8
chitinase-like 1
chrX_-_8011952 5.26 ENSMUST00000115615.9
ENSMUST00000115616.8
ENSMUST00000115621.9
RNA binding motif (RNP1, RRM) protein 3
chr4_+_120523758 5.07 ENSMUST00000094814.6
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr3_-_107145968 4.96 ENSMUST00000197758.5
prokineticin 1
chrX_-_8011918 4.90 ENSMUST00000115619.8
ENSMUST00000115617.10
ENSMUST00000040010.10
RNA binding motif (RNP1, RRM) protein 3
chr14_-_70864448 4.31 ENSMUST00000110984.4
dematin actin binding protein
chr7_+_43086432 4.00 ENSMUST00000070518.4
natural killer cell group 7 sequence
chr1_+_134109888 3.70 ENSMUST00000156873.8
chitinase-like 1
chr6_+_41498716 3.47 ENSMUST00000070380.5
protease, serine 2
chr14_-_70864666 3.41 ENSMUST00000022694.17
dematin actin binding protein
chr6_+_40941688 3.18 ENSMUST00000076638.7
RIKEN cDNA 1810009J06 gene
chr8_-_71060911 3.12 ENSMUST00000210580.2
ENSMUST00000211608.2
ENSMUST00000049908.11
single stranded DNA binding protein 4
chr7_+_43086554 3.04 ENSMUST00000206741.2
natural killer cell group 7 sequence
chrX_-_72974357 2.49 ENSMUST00000155597.2
ENSMUST00000114379.8
renin binding protein
chr4_-_63965161 2.49 ENSMUST00000107377.10
tenascin C
chr14_-_55950939 2.46 ENSMUST00000168729.8
ENSMUST00000228123.2
ENSMUST00000178034.9
transglutaminase 1, K polypeptide
chr3_+_96939732 2.41 ENSMUST00000132256.8
ENSMUST00000072600.7
gap junction protein, alpha 5
chr17_+_29309942 2.40 ENSMUST00000119901.9
cyclin-dependent kinase inhibitor 1A (P21)
chr5_-_140687995 2.36 ENSMUST00000135028.5
ENSMUST00000077890.12
ENSMUST00000041783.14
ENSMUST00000142081.6
IQ motif containing E
chrX_-_72974440 2.22 ENSMUST00000116578.8
renin binding protein
chr15_-_97729341 1.97 ENSMUST00000079838.14
ENSMUST00000118294.8
histone deacetylase 7
chr11_+_69886603 1.87 ENSMUST00000018716.10
PHD finger protein 23
chr7_-_99770653 1.86 ENSMUST00000208670.2
ENSMUST00000032969.14
polymerase (DNA-directed), delta 3, accessory subunit
chr6_+_129374260 1.84 ENSMUST00000032262.14
C-type lectin domain family 1, member b
chr8_+_121463090 1.84 ENSMUST00000160943.3
ENSMUST00000047737.10
ENSMUST00000162658.8
interferon regulatory factor 8
chr3_-_96201248 1.77 ENSMUST00000029748.8
Fc receptor, IgG, high affinity I
chr11_+_69886652 1.73 ENSMUST00000101526.9
PHD finger protein 23
chr10_-_61619790 1.69 ENSMUST00000020283.5
macroH2A.2 histone
chr3_-_144412394 1.63 ENSMUST00000200532.2
SH3-domain GRB2-like B1 (endophilin)
chr4_+_114945905 1.59 ENSMUST00000171877.8
ENSMUST00000177647.8
ENSMUST00000106548.9
ENSMUST00000030488.3
PDZK1 interacting protein 1
chr6_+_129374441 1.54 ENSMUST00000112081.9
ENSMUST00000112079.3
C-type lectin domain family 1, member b
chr2_-_163592127 1.44 ENSMUST00000017841.4
adenosine deaminase
chr5_+_136023649 1.39 ENSMUST00000111142.9
ENSMUST00000111145.10
ENSMUST00000111144.8
ENSMUST00000199239.5
ENSMUST00000005072.10
ENSMUST00000130345.2
deltex 2, E3 ubiquitin ligase
chr3_-_88417251 1.39 ENSMUST00000149068.2
lamin A
chr7_-_99770280 1.30 ENSMUST00000208184.2
polymerase (DNA-directed), delta 3, accessory subunit
chr12_-_91351177 1.30 ENSMUST00000141429.8
centrosomal protein 128
chr6_+_42326760 1.26 ENSMUST00000203652.3
ENSMUST00000070635.13
zyxin
chr4_+_63478478 1.24 ENSMUST00000080336.4
transmembrane protein 268
chr19_-_46950355 1.23 ENSMUST00000236501.2
5'-nucleotidase, cytosolic II
chr7_+_79836581 1.23 ENSMUST00000032754.9
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr16_-_20245071 1.21 ENSMUST00000115547.9
ENSMUST00000096199.5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr6_+_42326714 1.18 ENSMUST00000203846.3
zyxin
chr10_+_128139227 1.13 ENSMUST00000218315.2
ENSMUST00000219721.2
PAN2 poly(A) specific ribonuclease subunit
chr10_-_95252712 1.13 ENSMUST00000020215.16
suppressor of cytokine signaling 2
chr7_-_30643444 1.12 ENSMUST00000062620.9
hepcidin antimicrobial peptide
chr4_+_63478454 1.09 ENSMUST00000124332.8
ENSMUST00000150360.8
transmembrane protein 268
chr9_-_30833748 1.08 ENSMUST00000065112.7
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
chr7_-_127185512 1.05 ENSMUST00000205839.2
coiled-coil domain containing 189
chr9_+_86625694 1.05 ENSMUST00000179574.2
ENSMUST00000036426.13
protease, serine 35
chr12_-_112637998 1.04 ENSMUST00000128300.9
thymoma viral proto-oncogene 1
chr1_+_171594690 1.01 ENSMUST00000015460.5
signaling lymphocytic activation molecule family member 1
chr15_-_93417380 1.00 ENSMUST00000109255.3
prickle planar cell polarity protein 1
chr5_-_148988110 1.00 ENSMUST00000110505.8
high mobility group box 1
chr4_-_129472328 1.00 ENSMUST00000052835.9
family with sequence similarity 167, member B
chr10_+_128139191 1.00 ENSMUST00000005825.8
PAN2 poly(A) specific ribonuclease subunit
chr11_+_101136821 1.00 ENSMUST00000129680.8
receptor (calcitonin) activity modifying protein 2
chr16_-_20245138 0.96 ENSMUST00000079158.13
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr11_-_59937302 0.96 ENSMUST00000000310.14
ENSMUST00000102693.9
ENSMUST00000148512.2
phosphatidylethanolamine N-methyltransferase
chr15_-_37459570 0.95 ENSMUST00000119730.8
ENSMUST00000120746.8
neurocalcin delta
chr4_-_136613498 0.92 ENSMUST00000046384.9
complement component 1, q subcomponent, beta polypeptide
chr7_-_100232276 0.91 ENSMUST00000152876.3
ENSMUST00000150042.8
ENSMUST00000132888.9
mitochondrial ribosomal protein L48
chr2_+_150590956 0.90 ENSMUST00000094467.6
ectonucleoside triphosphate diphosphohydrolase 6
chr6_-_65121892 0.89 ENSMUST00000031982.5
hematopoietic prostaglandin D synthase
chr6_+_28475099 0.88 ENSMUST00000168362.2
staphylococcal nuclease and tudor domain containing 1
chr5_+_90708962 0.83 ENSMUST00000094615.8
ENSMUST00000200765.2
albumin superfamily member 1
chr7_-_126224848 0.79 ENSMUST00000032961.4
nuclear protein transcription regulator 1
chr6_+_42326528 0.78 ENSMUST00000203329.3
zyxin
chr11_-_45846291 0.78 ENSMUST00000011398.13
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr8_+_11778039 0.75 ENSMUST00000110909.9
Rho guanine nucleotide exchange factor (GEF7)
chr6_-_122317484 0.71 ENSMUST00000112600.9
polyhomeotic 1
chr7_-_44665639 0.69 ENSMUST00000085383.11
SR-related CTD-associated factor 1
chr4_-_129534853 0.67 ENSMUST00000046425.16
ENSMUST00000133803.8
taxilin alpha
chr4_-_129534752 0.66 ENSMUST00000132217.8
ENSMUST00000130017.2
ENSMUST00000154105.8
taxilin alpha
chr7_-_100505486 0.65 ENSMUST00000139604.8
RELT tumor necrosis factor receptor
chr12_+_86129329 0.65 ENSMUST00000054565.8
ENSMUST00000222821.2
ENSMUST00000222905.2
intraflagellar transport 43
chr19_+_37184927 0.64 ENSMUST00000024078.15
ENSMUST00000112391.8
membrane associated ring-CH-type finger 5
chr7_-_108774367 0.63 ENSMUST00000207178.2
LIM domain only 1
chr8_+_11777721 0.63 ENSMUST00000210104.2
Rho guanine nucleotide exchange factor (GEF7)
chr17_-_48145466 0.62 ENSMUST00000066368.13
MyoD family inhibitor
chr8_+_71126012 0.62 ENSMUST00000146972.3
ENSMUST00000210071.2
ENSMUST00000210987.2
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr14_-_118943591 0.61 ENSMUST00000036554.14
ENSMUST00000166646.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr17_+_36134398 0.61 ENSMUST00000173493.8
ENSMUST00000173147.8
flotillin 1
chr18_-_33596890 0.61 ENSMUST00000237066.2
neuronal regeneration related protein
chr6_-_48025845 0.61 ENSMUST00000095944.10
zinc finger protein 777
chr14_+_55842002 0.60 ENSMUST00000138037.2
interferon regulatory factor 9
chr18_-_38417390 0.59 ENSMUST00000025311.8
protocadherin 12
chr8_-_112064783 0.57 ENSMUST00000056157.14
ENSMUST00000120432.3
mixed lineage kinase domain-like
chr10_-_78427721 0.57 ENSMUST00000040580.7
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr8_-_125296435 0.56 ENSMUST00000238882.2
ENSMUST00000063278.7
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr8_+_71125876 0.55 ENSMUST00000034311.15
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr3_+_89136353 0.54 ENSMUST00000041142.4
mucin 1, transmembrane
chr11_-_98620200 0.54 ENSMUST00000126565.2
ENSMUST00000100500.9
ENSMUST00000017354.13
mediator complex subunit 24
chr3_-_108117754 0.52 ENSMUST00000117784.8
ENSMUST00000119650.8
ENSMUST00000117409.8
ataxin 7-like 2
chr2_+_128942900 0.52 ENSMUST00000103205.11
polymerase (RNA) I polypeptide B
chr2_+_128942919 0.52 ENSMUST00000028874.8
polymerase (RNA) I polypeptide B
chr10_-_79911245 0.50 ENSMUST00000217972.2
strawberry notch 2
chr10_-_81102740 0.50 ENSMUST00000046114.5
mitochondrial ribosomal protein L54
chr10_+_40225272 0.48 ENSMUST00000044672.11
ENSMUST00000095743.4
cyclin-dependent kinase 19
chr18_+_42644552 0.48 ENSMUST00000237602.2
ENSMUST00000236088.2
ENSMUST00000025375.15
transcription elongation regulator 1 (CA150)
chr4_-_129534403 0.47 ENSMUST00000084264.12
taxilin alpha
chr5_+_75312939 0.46 ENSMUST00000202681.4
ENSMUST00000000476.15
platelet derived growth factor receptor, alpha polypeptide
chr10_-_95253042 0.45 ENSMUST00000135822.8
suppressor of cytokine signaling 2
chr2_-_126341757 0.45 ENSMUST00000040128.12
ATPase, class I, type 8B, member 4
chrX_+_158086253 0.44 ENSMUST00000112491.2
ribosomal protein S6 kinase polypeptide 3
chr17_+_36134122 0.44 ENSMUST00000001569.15
ENSMUST00000174080.8
flotillin 1
chr9_+_86454018 0.44 ENSMUST00000185566.7
ENSMUST00000034988.10
ENSMUST00000179212.3
RWD domain containing 2A
chr1_+_171041539 0.44 ENSMUST00000005820.11
ENSMUST00000075469.12
ENSMUST00000155126.8
nuclear receptor subfamily 1, group I, member 3
chr18_-_33596468 0.43 ENSMUST00000171533.9
neuronal regeneration related protein
chr6_+_127423779 0.43 ENSMUST00000112191.8
poly (ADP-ribose) polymerase family, member 11
chr18_-_52662917 0.43 ENSMUST00000171470.8
lysyl oxidase
chr13_-_46881388 0.40 ENSMUST00000021803.10
nucleoporin 153
chr18_-_38417444 0.39 ENSMUST00000194012.2
protocadherin 12
chr5_+_52991351 0.38 ENSMUST00000031072.14
anaphase promoting complex subunit 4
chr1_+_36346824 0.38 ENSMUST00000142319.8
ENSMUST00000097778.9
ENSMUST00000115031.8
ENSMUST00000115032.8
ENSMUST00000137906.2
ENSMUST00000115029.2
AT rich interactive domain 5A (MRF1-like)
chr16_-_31898088 0.38 ENSMUST00000023467.9
p21 (RAC1) activated kinase 2
chr19_-_46315543 0.37 ENSMUST00000223917.2
ENSMUST00000224447.2
ENSMUST00000041391.5
ENSMUST00000096029.12
pleckstrin and Sec7 domain containing
chr16_+_17326810 0.37 ENSMUST00000231292.2
leucine-zipper-like transcriptional regulator, 1
chr18_-_33596792 0.37 ENSMUST00000051087.16
neuronal regeneration related protein
chr1_+_171041583 0.36 ENSMUST00000111328.8
nuclear receptor subfamily 1, group I, member 3
chr19_-_40260286 0.36 ENSMUST00000182432.2
PDZ and LIM domain 1 (elfin)
chr18_-_52662728 0.36 ENSMUST00000025409.9
lysyl oxidase
chr9_+_44893077 0.35 ENSMUST00000034602.9
CD3 antigen, delta polypeptide
chr16_+_17327076 0.35 ENSMUST00000232242.2
leucine-zipper-like transcriptional regulator, 1
chr17_+_36134450 0.35 ENSMUST00000172846.2
flotillin 1
chr11_+_81926394 0.35 ENSMUST00000000193.6
chemokine (C-C motif) ligand 2
chr7_+_45204317 0.34 ENSMUST00000107752.12
hydroxysteroid (17-beta) dehydrogenase 14
chr17_+_34364206 0.34 ENSMUST00000041982.9
ENSMUST00000171231.8
histocompatibility 2, class II, locus Mb2
chr5_+_35198853 0.34 ENSMUST00000030985.10
ENSMUST00000202573.2
hepatocyte growth factor activator
chr7_+_89780785 0.32 ENSMUST00000208684.2
phosphatidylinositol binding clathrin assembly protein
chr8_-_106052884 0.30 ENSMUST00000210412.2
ENSMUST00000210801.2
ENSMUST00000070508.8
leucine rich repeat containing 29
chr10_+_20188207 0.30 ENSMUST00000092678.10
ENSMUST00000043881.12
BCL2-associated transcription factor 1
chr9_-_123507937 0.29 ENSMUST00000040960.13
solute carrier family 6 (neurotransmitter transporter), member 20A
chr9_-_71393175 0.27 ENSMUST00000233263.2
ENSMUST00000034720.12
polymerase (RNA) II (DNA directed) polypeptide M
chr19_-_40260060 0.27 ENSMUST00000068439.13
PDZ and LIM domain 1 (elfin)
chr17_+_28910302 0.21 ENSMUST00000004990.14
ENSMUST00000114754.8
ENSMUST00000062694.16
mitogen-activated protein kinase 14
chr18_+_37453427 0.20 ENSMUST00000078271.4
protocadherin beta 5
chr18_-_43610829 0.19 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr11_+_53660834 0.19 ENSMUST00000108920.10
ENSMUST00000140866.9
ENSMUST00000108922.9
interferon regulatory factor 1
chr17_+_28910393 0.18 ENSMUST00000124886.9
ENSMUST00000114758.9
mitogen-activated protein kinase 14
chr10_+_20188269 0.18 ENSMUST00000185800.7
BCL2-associated transcription factor 1
chrX_-_99670174 0.18 ENSMUST00000015812.12
PDZ domain containing 11
chr6_-_122317457 0.17 ENSMUST00000160843.8
polyhomeotic 1
chr5_-_34671236 0.17 ENSMUST00000114359.2
ENSMUST00000030991.14
ENSMUST00000087737.10
TNFAIP3 interacting protein 2
chr16_-_20244631 0.16 ENSMUST00000077867.10
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr14_-_122153185 0.15 ENSMUST00000055475.9
G protein-coupled receptor 18
chr9_-_44437694 0.15 ENSMUST00000062215.8
chemokine (C-X-C motif) receptor 5
chr8_-_112064393 0.15 ENSMUST00000145862.3
mixed lineage kinase domain-like
chr19_+_36811615 0.15 ENSMUST00000025729.12
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chrX_-_8118541 0.14 ENSMUST00000115594.8
ENSMUST00000115595.8
ENSMUST00000033513.10
FtsJ RNA methyltransferase homolog 1 (E. coli)
chr12_-_11315755 0.13 ENSMUST00000166117.4
ENSMUST00000219600.2
ENSMUST00000218487.2
GEN1, Holliday junction 5' flap endonuclease
chr11_-_72106418 0.13 ENSMUST00000021157.9
mediator complex subunit 31
chr5_-_6926523 0.12 ENSMUST00000164784.2
zinc finger protein 804B
chr4_+_83335947 0.12 ENSMUST00000030206.10
ENSMUST00000071544.11
small nuclear RNA activating complex, polypeptide 3
chr16_+_21613068 0.11 ENSMUST00000211443.2
ENSMUST00000231300.2
ENSMUST00000209449.2
ENSMUST00000181780.9
ENSMUST00000209728.2
ENSMUST00000181960.3
ENSMUST00000209429.2
ENSMUST00000180830.3
ENSMUST00000231988.2
RIKEN cDNA 1300002E11 gene
mitogen-activated protein kinase kinase kinase 13
chr15_-_37458768 0.10 ENSMUST00000116445.9
neurocalcin delta
chr17_+_34406523 0.09 ENSMUST00000170086.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr16_-_42160957 0.08 ENSMUST00000102817.5
growth associated protein 43
chr11_+_101315893 0.08 ENSMUST00000040561.6
RUN domain containing 1
chr15_+_34238174 0.07 ENSMUST00000022867.5
ENSMUST00000226627.2
lysosomal-associated protein transmembrane 4B
chr16_+_91169770 0.06 ENSMUST00000089042.7
interferon (alpha and beta) receptor 2
chr11_+_96173355 0.05 ENSMUST00000125410.2
homeobox B8
chr17_+_34406762 0.05 ENSMUST00000041633.15
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr8_-_71229293 0.05 ENSMUST00000034296.15
phosphoinositide-3-kinase regulatory subunit 2
chr16_-_59138611 0.04 ENSMUST00000216261.2
olfactory receptor 204
chr2_-_117173312 0.04 ENSMUST00000178884.8
RAS guanyl releasing protein 1
chr2_-_117173190 0.03 ENSMUST00000173541.8
ENSMUST00000172901.8
ENSMUST00000173252.2
RAS guanyl releasing protein 1
chr2_-_37312881 0.03 ENSMUST00000112936.4
ENSMUST00000112934.8
ring finger and CCCH-type zinc finger domains 2
chr12_-_108859123 0.02 ENSMUST00000161154.2
ENSMUST00000161410.8
tryptophanyl-tRNA synthetase
chr8_+_26022141 0.02 ENSMUST00000210846.2
ENSMUST00000167764.2
fibroblast growth factor receptor 1
chr3_+_138233004 0.02 ENSMUST00000196990.5
ENSMUST00000200239.5
ENSMUST00000200100.2
eukaryotic translation initiation factor 4E
chr2_+_101716577 0.01 ENSMUST00000028584.8
COMM domain containing 9
chr3_-_57202301 0.01 ENSMUST00000171384.8
transmembrane 4 superfamily member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.8 GO:0044010 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) membrane disruption in other organism(GO:0051673) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
1.9 5.6 GO:0060217 hemangioblast cell differentiation(GO:0060217)
1.3 7.7 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.8 2.4 GO:0010645 atrial ventricular junction remodeling(GO:0003294) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.7 4.7 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.6 2.5 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.6 1.8 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.5 1.6 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.5 1.4 GO:0002314 germinal center B cell differentiation(GO:0002314) adenosine catabolic process(GO:0006154) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) purine deoxyribonucleoside metabolic process(GO:0046122) negative regulation of mucus secretion(GO:0070256)
0.4 3.6 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.4 9.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.4 3.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.3 1.0 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.3 1.0 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.3 1.0 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.3 1.1 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.3 1.0 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.3 1.0 GO:0017126 nucleologenesis(GO:0017126)
0.2 1.4 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.2 1.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 2.5 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.2 10.2 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.2 3.5 GO:0031000 response to caffeine(GO:0031000)
0.2 0.5 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.2 2.4 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 0.9 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 1.0 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.4 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.5 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 1.0 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 2.0 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.3 GO:0035702 immune complex clearance by monocytes and macrophages(GO:0002436) monocyte homeostasis(GO:0035702) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
0.1 0.6 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 2.1 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1 0.4 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.5 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 1.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 1.8 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.1 2.7 GO:0030220 platelet formation(GO:0030220)
0.1 0.3 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.3 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.2 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 1.6 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.6 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.8 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 4.8 GO:0043627 response to estrogen(GO:0043627)
0.0 1.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.2 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0 0.4 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.6 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.6 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.4 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 4.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.7 GO:0070266 necroptotic process(GO:0070266)
0.0 0.2 GO:0023035 CD40 signaling pathway(GO:0023035) toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.9 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 1.7 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0033193 Lsd1/2 complex(GO:0033193)
1.6 9.8 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
1.1 7.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.8 2.4 GO:0070557 PCNA-p21 complex(GO:0070557)
0.4 2.1 GO:0031251 PAN complex(GO:0031251)
0.2 1.4 GO:0005638 lamin filament(GO:0005638)
0.2 1.0 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 0.6 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 1.4 GO:0000322 storage vacuole(GO:0000322)
0.1 2.4 GO:0005922 connexon complex(GO:0005922)
0.1 1.2 GO:0005688 U6 snRNP(GO:0005688)
0.1 1.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 2.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.9 GO:0097433 dense body(GO:0097433)
0.1 11.4 GO:0015934 large ribosomal subunit(GO:0015934)
0.1 1.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.9 GO:0001739 sex chromatin(GO:0001739)
0.1 0.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.6 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.3 GO:0044299 C-fiber(GO:0044299)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 5.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 2.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 1.0 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.7 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 10.5 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
1.1 10.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.8 2.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.8 9.0 GO:0008061 chitin binding(GO:0008061)
0.6 2.4 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.3 1.0 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.3 9.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.3 4.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.3 1.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 0.8 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.3 1.8 GO:0019770 IgG receptor activity(GO:0019770)
0.2 2.5 GO:0045545 syndecan binding(GO:0045545)
0.2 2.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 0.9 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 1.0 GO:0097643 amylin receptor activity(GO:0097643)
0.2 0.5 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 1.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.2 GO:0042731 PH domain binding(GO:0042731)
0.1 2.0 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 5.6 GO:0070888 E-box binding(GO:0070888)
0.1 7.1 GO:0043621 protein self-association(GO:0043621)
0.1 5.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 1.6 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.1 1.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 1.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.0 0.9 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 4.0 GO:0008083 growth factor activity(GO:0008083)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 1.1 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 1.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 1.7 GO:0043492 ATPase activity, coupled to movement of substances(GO:0043492)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 2.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 4.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 3.5 REACTOME DEFENSINS Genes involved in Defensins
0.2 3.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 2.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.9 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 2.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 5.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.9 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)