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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Stat4_Stat3_Stat5b

Z-value: 1.86

Motif logo

Transcription factors associated with Stat4_Stat3_Stat5b

Gene Symbol Gene ID Gene Info
ENSMUSG00000062939.12 Stat4
ENSMUSG00000004040.17 Stat3
ENSMUSG00000020919.12 Stat5b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Stat3mm39_v1_chr11_-_100830183_1008302620.555.3e-04Click!
Stat5bmm39_v1_chr11_-_100713348_1007134050.511.4e-03Click!
Stat4mm39_v1_chr1_+_52047368_52047413-0.325.7e-02Click!

Activity profile of Stat4_Stat3_Stat5b motif

Sorted Z-values of Stat4_Stat3_Stat5b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat4_Stat3_Stat5b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_+_30608433 11.80 ENSMUST00000120269.11
ENSMUST00000078490.14
ENSMUST00000006703.15
inter alpha-trypsin inhibitor, heavy chain 4
chr14_+_30608478 11.68 ENSMUST00000168782.4
inter alpha-trypsin inhibitor, heavy chain 4
chr3_-_107145968 10.43 ENSMUST00000197758.5
prokineticin 1
chr8_-_125296435 8.55 ENSMUST00000238882.2
ENSMUST00000063278.7
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr6_+_41498716 7.94 ENSMUST00000070380.5
protease, serine 2
chr10_-_95252712 7.18 ENSMUST00000020215.16
suppressor of cytokine signaling 2
chr11_+_69945157 6.91 ENSMUST00000108585.9
ENSMUST00000018699.13
asialoglycoprotein receptor 1
chr17_-_56428968 6.88 ENSMUST00000041357.9
leucine-rich alpha-2-glycoprotein 1
chr19_+_40078132 6.49 ENSMUST00000068094.13
ENSMUST00000080171.3
cytochrome P450, family 2, subfamily c, polypeptide 50
chr13_-_42001075 6.48 ENSMUST00000179758.8
androgen dependent TFPI regulating protein
chr13_-_42001102 5.89 ENSMUST00000121404.8
androgen dependent TFPI regulating protein
chr9_+_107173907 5.75 ENSMUST00000168260.2
cytokine inducible SH2-containing protein
chr13_-_42000958 5.56 ENSMUST00000072012.10
androgen dependent TFPI regulating protein
chr11_-_83421333 5.51 ENSMUST00000035938.3
chemokine (C-C motif) ligand 5
chr11_+_78389913 5.38 ENSMUST00000017488.5
vitronectin
chr4_+_148686985 5.15 ENSMUST00000105701.9
ENSMUST00000052060.7
mannan-binding lectin serine peptidase 2
chr10_-_126906123 5.03 ENSMUST00000060991.6
tetraspanin 31
chr9_+_107174081 4.89 ENSMUST00000167072.2
cytokine inducible SH2-containing protein
chr12_-_103956176 4.83 ENSMUST00000151709.3
ENSMUST00000176246.3
ENSMUST00000074693.13
ENSMUST00000120251.9
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr3_+_20011251 4.70 ENSMUST00000108328.8
ceruloplasmin
chr11_+_48977852 4.55 ENSMUST00000046704.7
ENSMUST00000203810.3
ENSMUST00000203149.3
interferon gamma inducible protein 47
olfactory receptor 56
chr7_+_107166653 4.52 ENSMUST00000120990.2
olfactomedin-like 1
chr3_+_20011201 4.46 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
ceruloplasmin
chr3_+_20011405 4.38 ENSMUST00000108325.9
ceruloplasmin
chr15_+_10224052 3.99 ENSMUST00000128450.8
ENSMUST00000148257.8
ENSMUST00000128921.8
prolactin receptor
chr11_+_48977888 3.93 ENSMUST00000214804.2
interferon gamma inducible protein 47
chrX_+_59044796 3.91 ENSMUST00000033477.5
coagulation factor IX
chr6_+_41331039 3.87 ENSMUST00000072103.7
trypsin 10
chr10_-_95253042 3.86 ENSMUST00000135822.8
suppressor of cytokine signaling 2
chr18_+_32087883 3.86 ENSMUST00000223753.2
LIM and senescent cell antigen like domains 2
chr1_-_172722589 3.85 ENSMUST00000027824.7
serum amyloid P-component
chr1_-_155688551 3.78 ENSMUST00000194632.2
ENSMUST00000111764.8
quiescin Q6 sulfhydryl oxidase 1
chr5_+_8010445 3.69 ENSMUST00000115421.3
STEAP family member 4
chr7_-_81356653 3.51 ENSMUST00000026922.15
homer scaffolding protein 2
chr1_-_155688635 3.41 ENSMUST00000035325.15
quiescin Q6 sulfhydryl oxidase 1
chr6_-_41291634 3.40 ENSMUST00000064324.12
trypsin 5
chr9_-_71070506 3.34 ENSMUST00000074465.9
aquaporin 9
chr7_-_81356557 3.32 ENSMUST00000207983.2
homer scaffolding protein 2
chr14_-_55950939 3.26 ENSMUST00000168729.8
ENSMUST00000228123.2
ENSMUST00000178034.9
transglutaminase 1, K polypeptide
chr7_+_107166925 3.22 ENSMUST00000239087.2
olfactomedin-like 1
chr8_+_105652867 3.13 ENSMUST00000034355.11
ENSMUST00000109410.4
carboxylesterase 2E
chr15_-_54783357 3.05 ENSMUST00000167541.3
ENSMUST00000171545.9
ENSMUST00000041591.16
ENSMUST00000173516.8
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr2_-_28453374 2.89 ENSMUST00000028161.6
carboxyl ester lipase
chr1_+_171041539 2.88 ENSMUST00000005820.11
ENSMUST00000075469.12
ENSMUST00000155126.8
nuclear receptor subfamily 1, group I, member 3
chr1_+_171041583 2.88 ENSMUST00000111328.8
nuclear receptor subfamily 1, group I, member 3
chr16_-_35691914 2.86 ENSMUST00000042665.9
poly (ADP-ribose) polymerase family, member 14
chr17_+_43978377 2.84 ENSMUST00000233627.2
ENSMUST00000233437.2
cytochrome P450, family 39, subfamily a, polypeptide 1
chr5_+_90708962 2.80 ENSMUST00000094615.8
ENSMUST00000200765.2
albumin superfamily member 1
chr17_+_43978280 2.71 ENSMUST00000170988.2
cytochrome P450, family 39, subfamily a, polypeptide 1
chr2_-_84605764 2.68 ENSMUST00000111641.2
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr7_-_30623592 2.64 ENSMUST00000217812.2
ENSMUST00000074671.9
hepcidin antimicrobial peptide 2
chr5_+_137568982 2.63 ENSMUST00000196471.5
ENSMUST00000198783.5
transferrin receptor 2
chr17_+_34406523 2.62 ENSMUST00000170086.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_+_34406762 2.62 ENSMUST00000041633.15
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_+_121323577 2.59 ENSMUST00000032200.16
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr15_+_25933632 2.55 ENSMUST00000228327.2
reticulophagy regulator 1
chr16_+_62674661 2.54 ENSMUST00000023629.9
protein S (alpha)
chr6_+_34389269 2.52 ENSMUST00000007449.9
aldo-keto reductase family 1, member B7
chr17_+_25097199 2.49 ENSMUST00000050714.8
insulin-like growth factor binding protein, acid labile subunit
chr18_-_3281089 2.47 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr19_+_4761181 2.44 ENSMUST00000008991.8
spectrin beta, non-erythrocytic 2
chr7_-_105249308 2.39 ENSMUST00000210531.2
ENSMUST00000033185.10
hemopexin
chr7_+_127399776 2.39 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr11_-_59937302 2.35 ENSMUST00000000310.14
ENSMUST00000102693.9
ENSMUST00000148512.2
phosphatidylethanolamine N-methyltransferase
chr7_+_127399789 2.35 ENSMUST00000125188.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr14_+_66208253 2.33 ENSMUST00000138191.8
clusterin
chr14_+_66208059 2.23 ENSMUST00000127387.8
clusterin
chr7_+_127400016 2.16 ENSMUST00000106271.2
ENSMUST00000138432.2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr17_-_34406193 2.12 ENSMUST00000173831.3
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr4_-_57916283 2.11 ENSMUST00000063816.6
RIKEN cDNA D630039A03 gene
chr15_-_37458768 2.08 ENSMUST00000116445.9
neurocalcin delta
chr11_+_120421496 2.08 ENSMUST00000026119.8
glucagon receptor
chr14_+_66208498 2.06 ENSMUST00000128539.8
clusterin
chr3_+_82915031 2.02 ENSMUST00000048486.13
ENSMUST00000194175.2
fibrinogen gamma chain
chr1_-_170803680 2.00 ENSMUST00000027966.14
ENSMUST00000081103.12
ENSMUST00000159688.2
Fc receptor, IgG, low affinity IIb
chr6_-_5496261 1.98 ENSMUST00000203347.3
ENSMUST00000019721.7
pyruvate dehydrogenase kinase, isoenzyme 4
chr15_+_102011352 1.96 ENSMUST00000169627.9
tensin 2
chr11_-_48884999 1.95 ENSMUST00000146439.8
T cell specific GTPase 1
chr7_+_127399848 1.94 ENSMUST00000139068.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr7_+_29607917 1.91 ENSMUST00000186475.2
zinc finger protein 383
chr15_+_102011415 1.90 ENSMUST00000046144.10
tensin 2
chr5_+_89034666 1.88 ENSMUST00000148750.8
solute carrier family 4 (anion exchanger), member 4
chr17_+_29309942 1.85 ENSMUST00000119901.9
cyclin-dependent kinase inhibitor 1A (P21)
chr14_+_66208613 1.85 ENSMUST00000144619.2
clusterin
chr15_+_10249646 1.82 ENSMUST00000134410.8
prolactin receptor
chr17_-_79292856 1.80 ENSMUST00000118991.2
protein kinase D3
chr9_+_119168714 1.80 ENSMUST00000176351.8
acetyl-Coenzyme A acyltransferase 1A
chr10_-_127190280 1.79 ENSMUST00000059718.6
inhibin beta-E
chr19_+_38469504 1.79 ENSMUST00000182481.8
phospholipase C, epsilon 1
chr6_+_138118565 1.77 ENSMUST00000118091.8
microsomal glutathione S-transferase 1
chr15_-_37459570 1.75 ENSMUST00000119730.8
ENSMUST00000120746.8
neurocalcin delta
chr4_-_129472328 1.72 ENSMUST00000052835.9
family with sequence similarity 167, member B
chr11_+_81926394 1.62 ENSMUST00000000193.6
chemokine (C-C motif) ligand 2
chr17_-_32639936 1.62 ENSMUST00000170392.9
ENSMUST00000237165.2
ENSMUST00000235892.2
ENSMUST00000114455.3
peptidoglycan recognition protein 2
chr9_-_107556823 1.62 ENSMUST00000010205.9
guanine nucleotide binding protein, alpha transducing 1
chr2_-_84605732 1.58 ENSMUST00000023994.10
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr16_-_30086317 1.56 ENSMUST00000064856.9
carboxypeptidase N, polypeptide 2
chr5_+_134212836 1.55 ENSMUST00000016086.10
GTF2I repeat domain containing 2
chr8_+_105996469 1.52 ENSMUST00000172525.8
ENSMUST00000174837.8
ENSMUST00000173859.2
heat shock transcription factor 4
chr13_+_112600604 1.51 ENSMUST00000183663.8
ENSMUST00000184311.8
ENSMUST00000183886.8
interleukin 6 signal transducer
chr4_-_115875055 1.50 ENSMUST00000049095.6
fatty acid amide hydrolase
chr5_-_5564730 1.49 ENSMUST00000115445.8
ENSMUST00000179804.8
ENSMUST00000125110.2
ENSMUST00000115446.8
claudin 12
chr5_-_104125226 1.46 ENSMUST00000048118.15
hydroxysteroid (17-beta) dehydrogenase 13
chr5_+_35198853 1.45 ENSMUST00000030985.10
ENSMUST00000202573.2
hepatocyte growth factor activator
chr6_+_34575435 1.45 ENSMUST00000079391.10
ENSMUST00000142512.8
ENSMUST00000115027.8
ENSMUST00000115026.8
caldesmon 1
chr5_-_104125270 1.39 ENSMUST00000112803.3
hydroxysteroid (17-beta) dehydrogenase 13
chr5_-_104125192 1.37 ENSMUST00000120320.8
hydroxysteroid (17-beta) dehydrogenase 13
chr7_+_37883074 1.36 ENSMUST00000178876.10
RIKEN cDNA 1600014C10 gene
chr7_+_27878894 1.36 ENSMUST00000085901.13
ENSMUST00000172761.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr1_-_170804116 1.35 ENSMUST00000159969.8
Fc receptor, IgG, low affinity IIb
chr9_-_103107495 1.34 ENSMUST00000035158.16
transferrin
chr16_-_23807602 1.33 ENSMUST00000023151.6
B cell leukemia/lymphoma 6
chr18_-_33596890 1.32 ENSMUST00000237066.2
neuronal regeneration related protein
chr9_-_51240201 1.32 ENSMUST00000039959.11
ENSMUST00000238450.3
RIKEN cDNA 1810046K07 gene
chr5_-_5564873 1.32 ENSMUST00000060947.14
claudin 12
chr2_+_27567246 1.29 ENSMUST00000166775.8
retinoid X receptor alpha
chr1_-_169575203 1.29 ENSMUST00000027991.12
ENSMUST00000111357.2
regulator of G-protein signaling 4
chr7_+_27879650 1.27 ENSMUST00000172467.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr11_+_53660834 1.27 ENSMUST00000108920.10
ENSMUST00000140866.9
ENSMUST00000108922.9
interferon regulatory factor 1
chr2_+_27566452 1.26 ENSMUST00000129514.8
retinoid X receptor alpha
chr18_-_33596468 1.25 ENSMUST00000171533.9
neuronal regeneration related protein
chr5_-_77555881 1.25 ENSMUST00000163898.6
ENSMUST00000046746.10
insulin-like growth factor binding protein 7
chr17_-_28569574 1.24 ENSMUST00000114799.8
ENSMUST00000219703.3
TEA domain family member 3
chr2_-_168554774 1.22 ENSMUST00000123156.8
ENSMUST00000156555.2
ATPase, class II, type 9A
chr17_+_28910393 1.21 ENSMUST00000124886.9
ENSMUST00000114758.9
mitogen-activated protein kinase 14
chr15_+_88960327 1.18 ENSMUST00000165690.2
TraB domain containing
chr19_-_58443593 1.17 ENSMUST00000135730.2
ENSMUST00000152507.8
glial cell line derived neurotrophic factor family receptor alpha 1
chr11_-_109613040 1.15 ENSMUST00000020938.8
FAM20A, golgi associated secretory pathway pseudokinase
chr14_-_45767232 1.15 ENSMUST00000149723.2
fermitin family member 2
chr7_+_37883300 1.11 ENSMUST00000179992.10
RIKEN cDNA 1600014C10 gene
chr15_-_89263448 1.09 ENSMUST00000049968.9
outer dense fiber of sperm tails 3B
chr7_+_23969822 1.09 ENSMUST00000108438.10
zinc finger protein 93
chr11_-_48762170 1.08 ENSMUST00000049519.4
ENSMUST00000097271.4
immunity-related GTPase family M member 1
chr14_-_56499690 1.08 ENSMUST00000015581.6
granzyme B
chr9_+_20927271 1.08 ENSMUST00000086399.6
intercellular adhesion molecule 1
chr7_-_30643444 1.07 ENSMUST00000062620.9
hepcidin antimicrobial peptide
chr5_-_137608726 1.06 ENSMUST00000197912.5
procollagen C-endopeptidase enhancer protein
chr4_-_129534752 1.06 ENSMUST00000132217.8
ENSMUST00000130017.2
ENSMUST00000154105.8
taxilin alpha
chr18_-_33596792 1.06 ENSMUST00000051087.16
neuronal regeneration related protein
chr4_-_107889267 1.05 ENSMUST00000106709.9
podocan
chr15_-_75963446 1.05 ENSMUST00000228366.3
nuclear receptor binding protein 2
chr4_-_140344373 1.05 ENSMUST00000154979.2
Rho guanine nucleotide exchange factor (GEF) 10-like
chr7_+_101859542 1.04 ENSMUST00000140631.2
ENSMUST00000120879.8
ENSMUST00000146996.8
post-GPI attachment to proteins 2
chr11_-_21522193 1.03 ENSMUST00000102874.11
ENSMUST00000238916.2
malate dehydrogenase 1, NAD (soluble)
chr2_-_104324035 1.03 ENSMUST00000111124.8
homeodomain interacting protein kinase 3
chr6_+_108637577 1.02 ENSMUST00000032194.11
basic helix-loop-helix family, member e40
chr18_+_61178211 1.02 ENSMUST00000025522.11
ENSMUST00000115274.2
platelet derived growth factor receptor, beta polypeptide
chr11_+_53661251 1.02 ENSMUST00000138913.8
ENSMUST00000123376.8
ENSMUST00000019043.13
ENSMUST00000133291.3
interferon regulatory factor 1
chr12_+_76593799 1.01 ENSMUST00000218380.2
ENSMUST00000219751.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr9_-_44920899 1.01 ENSMUST00000102832.3
CD3 antigen, epsilon polypeptide
chr15_+_100202642 1.01 ENSMUST00000067752.5
ENSMUST00000229588.2
methyltransferase like 7A1
chr11_+_118324652 1.01 ENSMUST00000106286.3
C1q and tumor necrosis factor related protein 1
chr11_-_21521934 1.00 ENSMUST00000239073.2
malate dehydrogenase 1, NAD (soluble)
chr11_-_53321242 1.00 ENSMUST00000109019.8
ubiquinol-cytochrome c reductase, complex III subunit VII
chr4_-_107889136 0.99 ENSMUST00000106708.8
podocan
chr11_-_51748450 0.99 ENSMUST00000020655.14
ENSMUST00000109090.8
jade family PHD finger 2
chr17_-_28569721 0.99 ENSMUST00000156862.3
TEA domain family member 3
chr18_-_60860594 0.98 ENSMUST00000235795.2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr16_-_17711950 0.98 ENSMUST00000155943.9
DiGeorge syndrome critical region gene 2
chr10_-_53951796 0.96 ENSMUST00000105470.9
mannosidase 1, alpha
chr17_+_35345292 0.94 ENSMUST00000061859.7
DNA segment, Chr 17, human D6S53E
chr3_-_95646856 0.94 ENSMUST00000153026.8
ENSMUST00000123143.8
ENSMUST00000137912.8
ENSMUST00000029753.14
ENSMUST00000131376.8
ENSMUST00000117507.10
ENSMUST00000128885.8
ENSMUST00000147217.2
extracellular matrix protein 1
chr7_+_37883216 0.93 ENSMUST00000177983.2
RIKEN cDNA 1600014C10 gene
chr5_-_137608886 0.91 ENSMUST00000142675.8
procollagen C-endopeptidase enhancer protein
chr11_-_52165682 0.91 ENSMUST00000238914.2
transcription factor 7, T cell specific
chr3_-_82957104 0.91 ENSMUST00000048246.5
fibrinogen beta chain
chr3_+_89136353 0.90 ENSMUST00000041142.4
mucin 1, transmembrane
chr16_+_90535212 0.90 ENSMUST00000038197.3
melanocortin 2 receptor accessory protein
chr16_+_17327076 0.89 ENSMUST00000232242.2
leucine-zipper-like transcriptional regulator, 1
chr11_+_96920956 0.89 ENSMUST00000153482.2
secernin 2
chr15_-_60696790 0.89 ENSMUST00000100635.5
LRAT domain containing 1
chr6_-_136638926 0.87 ENSMUST00000032336.7
phospholipase B domain containing 1
chr1_+_178014983 0.85 ENSMUST00000161075.8
ENSMUST00000027783.14
desumoylating isopeptidase 2
chr16_-_56984137 0.85 ENSMUST00000231733.2
nitrilase family, member 2
chr11_-_69586347 0.84 ENSMUST00000181261.2
tumor necrosis factor (ligand) superfamily, member 12
chr4_+_107035566 0.83 ENSMUST00000030361.11
transmembrane protein 59
chr10_-_53951825 0.83 ENSMUST00000003843.16
mannosidase 1, alpha
chr19_-_10502468 0.83 ENSMUST00000025570.8
ENSMUST00000236455.2
succinate dehydrogenase complex assembly factor 2
chr8_-_111532495 0.83 ENSMUST00000150680.2
ENSMUST00000076846.11
interleukin 34
chr5_-_140687995 0.82 ENSMUST00000135028.5
ENSMUST00000077890.12
ENSMUST00000041783.14
ENSMUST00000142081.6
IQ motif containing E
chr11_-_78427061 0.81 ENSMUST00000017759.9
ENSMUST00000108277.3
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr9_+_123822000 0.81 ENSMUST00000039171.9
chemokine (C-C motif) receptor 3
chr4_+_11704438 0.80 ENSMUST00000108304.9
GTP binding protein (gene overexpressed in skeletal muscle)
chr2_+_101716577 0.79 ENSMUST00000028584.8
COMM domain containing 9
chr15_+_99290832 0.78 ENSMUST00000160635.8
ENSMUST00000161250.8
ENSMUST00000229392.2
ENSMUST00000161778.8
transmembrane BAX inhibitor motif containing 6
chr6_+_48372520 0.77 ENSMUST00000114571.8
ENSMUST00000031815.12
ENSMUST00000203371.3
KRAB-A domain containing 1
chr4_+_32238950 0.77 ENSMUST00000037416.13
BTB and CNC homology, basic leucine zipper transcription factor 2
chr1_+_178015287 0.77 ENSMUST00000159284.2
desumoylating isopeptidase 2
chr4_-_49473904 0.77 ENSMUST00000135976.2
acyl-coenzyme A amino acid N-acyltransferase 1
chr4_+_107035615 0.76 ENSMUST00000128123.3
ENSMUST00000106753.3
transmembrane protein 59
chr19_+_10502679 0.76 ENSMUST00000235674.2
cleavage and polyadenylation specific factor 7
chr3_+_90155479 0.75 ENSMUST00000015467.9
solute carrier family 39 (zinc transporter), member 1
chr9_+_108880221 0.75 ENSMUST00000200629.5
ENSMUST00000200515.5
ENSMUST00000197689.5
ENSMUST00000196954.5
ENSMUST00000198376.5
ENSMUST00000197483.5
ENSMUST00000198295.5
shisa family member 5
chr16_-_20549294 0.75 ENSMUST00000231826.2
ENSMUST00000076422.13
ENSMUST00000232217.2
thrombopoietin
chr10_+_128745214 0.74 ENSMUST00000220308.2
CD63 antigen
chr11_-_106469938 0.73 ENSMUST00000103070.3
testis expressed gene 2
chr8_-_11528615 0.73 ENSMUST00000033900.7
RAB20, member RAS oncogene family
chr6_+_108637816 0.73 ENSMUST00000163617.2
basic helix-loop-helix family, member e40
chr8_+_11777721 0.71 ENSMUST00000210104.2
Rho guanine nucleotide exchange factor (GEF7)
chr19_+_10502612 0.71 ENSMUST00000237321.2
ENSMUST00000038379.5
cleavage and polyadenylation specific factor 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
1.9 5.6 GO:0030573 bile acid catabolic process(GO:0030573)
1.7 5.2 GO:0046967 cytosol to ER transport(GO:0046967)
1.4 4.3 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.4 8.5 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.4 5.5 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.3 3.8 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.0 5.0 GO:0002434 immune complex clearance(GO:0002434)
1.0 5.9 GO:0038161 prolactin signaling pathway(GO:0038161)
0.9 3.7 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.9 11.7 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.8 3.3 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.8 3.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.7 2.9 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.6 2.3 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.5 6.5 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.5 1.6 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.5 2.6 GO:0009992 cellular water homeostasis(GO:0009992)
0.5 5.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.5 2.5 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.5 3.6 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.5 1.5 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.5 23.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.5 2.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.5 17.1 GO:0006825 copper ion transport(GO:0006825)
0.4 1.8 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.4 5.4 GO:0097421 smooth muscle cell-matrix adhesion(GO:0061302) liver regeneration(GO:0097421)
0.4 7.9 GO:0031000 response to caffeine(GO:0031000)
0.4 3.9 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.4 11.2 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.4 2.6 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.4 1.5 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.4 1.1 GO:0060464 lung lobe formation(GO:0060464) diaphragm morphogenesis(GO:0060540) cardiac muscle tissue regeneration(GO:0061026)
0.4 4.0 GO:0097460 ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.4 1.8 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 2.8 GO:0033762 response to glucagon(GO:0033762)
0.3 1.0 GO:2000591 cell migration involved in vasculogenesis(GO:0035441) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.3 3.1 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.3 1.3 GO:0043380 regulation of memory T cell differentiation(GO:0043380)
0.3 6.8 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.3 0.3 GO:0021762 substantia nigra development(GO:0021762)
0.3 0.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 0.9 GO:1904766 negative regulation of macroautophagy by TORC1 signaling(GO:1904766)
0.3 2.5 GO:0061709 reticulophagy(GO:0061709)
0.3 10.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3 1.4 GO:0031438 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.3 1.6 GO:0051342 sensory perception of umami taste(GO:0050917) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.3 1.6 GO:0032827 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.2 1.7 GO:0021539 subthalamus development(GO:0021539)
0.2 1.8 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.2 0.7 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.2 4.6 GO:0042730 fibrinolysis(GO:0042730)
0.2 2.0 GO:0006108 malate metabolic process(GO:0006108)
0.2 1.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 1.3 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.2 10.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.2 3.7 GO:0014850 response to muscle activity(GO:0014850)
0.2 1.0 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 0.7 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.2 2.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 6.3 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.2 1.1 GO:0046813 T cell antigen processing and presentation(GO:0002457) receptor-mediated virion attachment to host cell(GO:0046813)
0.2 0.5 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.2 1.0 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 0.5 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.2 0.5 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 0.8 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.2 6.9 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 0.5 GO:1903465 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.1 0.4 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 1.8 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 1.4 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 3.5 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.8 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.8 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.6 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.4 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.1 0.5 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 4.3 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.6 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.7 GO:2001023 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) regulation of response to drug(GO:2001023)
0.1 0.5 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.3 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.3 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.1 0.5 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 1.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.6 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.9 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.7 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.4 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.3 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 1.0 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.6 GO:0071484 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.5 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.8 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 0.3 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.1 0.5 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.9 GO:0033153 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.1 0.3 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.1 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.2 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 1.0 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 1.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.3 GO:0071725 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.3 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 2.1 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 1.0 GO:0097531 mast cell migration(GO:0097531)
0.1 0.7 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.1 0.2 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 1.5 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.2 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.6 GO:0032621 interleukin-18 production(GO:0032621)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 1.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.7 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 1.1 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.4 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 1.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 1.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 10.3 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 0.7 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.5 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.2 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.1 0.3 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.1 0.4 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.2 GO:0015755 response to fructose(GO:0009750) fructose transport(GO:0015755) cellular response to fructose stimulus(GO:0071332)
0.1 0.8 GO:0042448 progesterone metabolic process(GO:0042448)
0.1 0.1 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.2 GO:0003294 atrial ventricular junction remodeling(GO:0003294) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.4 GO:1904526 regulation of microtubule binding(GO:1904526)
0.0 0.1 GO:0021627 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.0 1.8 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 4.9 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 2.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.4 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.4 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.5 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 5.0 GO:0007586 digestion(GO:0007586)
0.0 0.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.4 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 3.5 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 2.5 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 1.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.3 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.9 GO:0070168 negative regulation of bone mineralization(GO:0030502) negative regulation of biomineral tissue development(GO:0070168)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.6 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.1 GO:0044849 estrous cycle(GO:0044849)
0.0 0.1 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.9 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685) termination of signal transduction(GO:0023021)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 1.1 GO:0070266 necroptotic process(GO:0070266)
0.0 1.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.8 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 3.5 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 1.0 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 2.6 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 0.4 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 0.5 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.1 GO:0021660 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.0 0.3 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 1.3 GO:0050810 regulation of steroid biosynthetic process(GO:0050810)
0.0 0.2 GO:0098907 T-tubule organization(GO:0033292) protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0 0.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 1.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 3.4 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.0 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.1 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 1.5 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.5 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.9 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.2 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.5 GO:0048820 hair follicle maturation(GO:0048820)
0.0 1.5 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 0.2 GO:0032735 positive regulation of interleukin-12 production(GO:0032735)
0.0 0.0 GO:0060379 negative regulation of cardioblast differentiation(GO:0051892) cardiac muscle cell myoblast differentiation(GO:0060379)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 1.0 GO:0031638 zymogen activation(GO:0031638)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 1.0 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.1 GO:0071236 cellular response to antibiotic(GO:0071236)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.7 5.2 GO:0042825 TAP complex(GO:0042825)
0.6 1.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.6 8.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.5 1.5 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.4 1.3 GO:0031904 endosome lumen(GO:0031904)
0.4 2.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 1.8 GO:0017177 glucosidase II complex(GO:0017177)
0.3 2.9 GO:0005577 fibrinogen complex(GO:0005577)
0.3 4.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 2.4 GO:0008091 spectrin(GO:0008091)
0.3 0.9 GO:0036020 endolysosome membrane(GO:0036020)
0.3 6.8 GO:0032426 stereocilium tip(GO:0032426)
0.2 2.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 65.1 GO:0072562 blood microparticle(GO:0072562)
0.2 1.1 GO:0044194 cytolytic granule(GO:0044194)
0.2 1.6 GO:0044299 C-fiber(GO:0044299)
0.2 2.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.2 2.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 1.4 GO:0030478 actin cap(GO:0030478)
0.1 1.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 7.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.5 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.6 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.1 GO:0000322 storage vacuole(GO:0000322)
0.1 0.6 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.6 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 1.1 GO:0044754 autolysosome(GO:0044754)
0.1 0.4 GO:0031251 PAN complex(GO:0031251)
0.1 0.4 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 2.3 GO:0042588 zymogen granule(GO:0042588)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.1 0.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.4 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 5.4 GO:0005811 lipid particle(GO:0005811)
0.0 2.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0005915 zonula adherens(GO:0005915)
0.0 1.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 2.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 4.1 GO:0055037 recycling endosome(GO:0055037)
0.0 2.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 2.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 2.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 9.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 32.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.8 GO:0051233 spindle midzone(GO:0051233)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 10.0 GO:0005912 adherens junction(GO:0005912)
0.0 0.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0043219 lateral loop(GO:0043219)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 15.5 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.3 GO:0044447 axoneme part(GO:0044447)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
1.9 5.6 GO:0008396 oxysterol 7-alpha-hydroxylase activity(GO:0008396)
1.8 11.0 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
1.8 5.5 GO:0031726 receptor signaling protein tyrosine kinase activator activity(GO:0030298) CCR1 chemokine receptor binding(GO:0031726)
1.7 5.2 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
1.6 6.5 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
1.4 7.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
1.2 13.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.2 5.8 GO:0004925 prolactin receptor activity(GO:0004925)
1.0 6.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
1.0 2.9 GO:0050253 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
0.9 23.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.7 2.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.7 3.3 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.6 1.9 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.6 3.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.6 1.8 GO:0008775 acetate CoA-transferase activity(GO:0008775)
0.6 4.0 GO:0019770 IgG receptor activity(GO:0019770)
0.5 3.8 GO:0001849 complement component C1q binding(GO:0001849)
0.5 2.6 GO:0004998 transferrin receptor activity(GO:0004998)
0.5 1.5 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.5 2.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.5 5.4 GO:0001846 opsonin binding(GO:0001846)
0.5 3.7 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.5 1.4 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.4 5.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.4 2.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.4 8.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.4 2.4 GO:0015232 heme transporter activity(GO:0015232)
0.4 1.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.4 2.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.4 4.3 GO:0001848 complement binding(GO:0001848)
0.3 3.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 8.5 GO:0051787 misfolded protein binding(GO:0051787)
0.3 2.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 2.5 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 0.8 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.3 1.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 1.6 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.3 2.0 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 0.7 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.2 5.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 1.4 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 0.7 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.2 2.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 2.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 2.7 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 0.5 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.2 0.6 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.2 0.6 GO:0019809 spermidine binding(GO:0019809)
0.2 1.8 GO:0043426 MRF binding(GO:0043426)
0.2 2.9 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 3.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 1.0 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.4 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.5 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 7.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 7.6 GO:0038024 cargo receptor activity(GO:0038024)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.7 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 21.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 2.1 GO:0070628 proteasome binding(GO:0070628)
0.1 1.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 1.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.5 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 11.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 1.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.6 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 3.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.3 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 1.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.4 GO:0004697 protein kinase C activity(GO:0004697)
0.1 9.0 GO:0008083 growth factor activity(GO:0008083)
0.1 0.4 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.2 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.6 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.8 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 1.0 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 0.7 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 11.9 GO:0003924 GTPase activity(GO:0003924)
0.0 1.6 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.6 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 3.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.0 GO:0015149 hexose transmembrane transporter activity(GO:0015149)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 1.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.8 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 1.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 2.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 2.1 GO:0005178 integrin binding(GO:0005178)
0.0 1.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.7 GO:0043531 ADP binding(GO:0043531)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 2.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 10.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.3 10.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 5.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 53.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 5.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 3.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 11.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 13.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 6.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 4.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 8.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.5 PID IL27 PATHWAY IL27-mediated signaling events
0.1 0.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 14.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.3 PID IL23 PATHWAY IL23-mediated signaling events
0.1 3.7 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 1.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 2.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 3.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.1 PID AURORA A PATHWAY Aurora A signaling
0.0 4.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.6 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 3.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID SHP2 PATHWAY SHP2 signaling
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 14.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.7 5.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.6 7.9 REACTOME DEFENSINS Genes involved in Defensins
0.5 26.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.5 6.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 14.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 5.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 0.7 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.2 2.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 3.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 4.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 1.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 1.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 2.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 1.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 3.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 2.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 6.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 18.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 3.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 5.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 2.1 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 2.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 8.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.8 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 6.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 5.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 3.7 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 1.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.5 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants