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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Stat6

Z-value: 1.39

Motif logo

Transcription factors associated with Stat6

Gene Symbol Gene ID Gene Info
ENSMUSG00000002147.19 Stat6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Stat6mm39_v1_chr10_+_127478844_127478914-0.028.9e-01Click!

Activity profile of Stat6 motif

Sorted Z-values of Stat6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_87684299 8.31 ENSMUST00000020779.11
myeloperoxidase
chr9_-_70328816 8.06 ENSMUST00000034742.8
cyclin B2
chr11_+_87684548 6.59 ENSMUST00000143021.9
myeloperoxidase
chr4_+_120523758 5.51 ENSMUST00000094814.6
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr15_-_82128888 4.10 ENSMUST00000089155.6
ENSMUST00000089157.11
centromere protein M
chr15_-_82128538 3.81 ENSMUST00000229747.2
ENSMUST00000230408.2
centromere protein M
chr14_-_56499690 3.80 ENSMUST00000015581.6
granzyme B
chr17_+_48607405 3.65 ENSMUST00000170941.3
triggering receptor expressed on myeloid cells-like 2
chr17_+_48606948 3.49 ENSMUST00000233092.2
triggering receptor expressed on myeloid cells-like 2
chr7_+_126690525 3.30 ENSMUST00000056288.7
ENSMUST00000206102.2
expressed sequence AI467606
chr18_+_50186349 3.22 ENSMUST00000148159.3
tumor necrosis factor, alpha-induced protein 8
chr1_+_134110142 3.18 ENSMUST00000082060.10
ENSMUST00000153856.8
ENSMUST00000133701.8
ENSMUST00000132873.8
chitinase-like 1
chrX_-_47551990 3.17 ENSMUST00000033429.9
ENSMUST00000140486.2
E74-like factor 4 (ets domain transcription factor)
chr5_+_114924106 2.94 ENSMUST00000137519.2
ankyrin repeat domain 13a
chr2_+_24235300 2.90 ENSMUST00000114485.9
ENSMUST00000114482.3
interleukin 1 receptor antagonist
chr7_-_126399574 2.74 ENSMUST00000106348.8
aldolase A, fructose-bisphosphate
chr1_+_134109888 2.74 ENSMUST00000156873.8
chitinase-like 1
chr2_-_113678999 2.72 ENSMUST00000102545.8
ENSMUST00000110948.8
Rho GTPase activating protein 11A
chr14_+_26722319 2.39 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr1_+_171594690 2.33 ENSMUST00000015460.5
signaling lymphocytic activation molecule family member 1
chr3_+_96939732 2.12 ENSMUST00000132256.8
ENSMUST00000072600.7
gap junction protein, alpha 5
chr7_-_126399208 2.09 ENSMUST00000133514.8
ENSMUST00000151137.8
aldolase A, fructose-bisphosphate
chr1_-_23948764 2.09 ENSMUST00000129254.8
small ArfGAP 1
chr7_-_126399778 2.02 ENSMUST00000141355.4
aldolase A, fructose-bisphosphate
chr17_-_90217868 1.99 ENSMUST00000086423.6
predicted pseudogene 10184
chr10_+_97315465 1.97 ENSMUST00000105287.11
decorin
chr11_-_83421333 1.88 ENSMUST00000035938.3
chemokine (C-C motif) ligand 5
chr19_+_10819896 1.88 ENSMUST00000025646.3
solute carrier family 15, member 3
chr6_+_8520006 1.85 ENSMUST00000162567.8
ENSMUST00000161217.8
glucocorticoid induced transcript 1
chr5_-_148329615 1.83 ENSMUST00000138257.8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr11_+_78079243 1.82 ENSMUST00000002128.14
ENSMUST00000150941.8
RAB34, member RAS oncogene family
chr17_+_29309942 1.72 ENSMUST00000119901.9
cyclin-dependent kinase inhibitor 1A (P21)
chr11_+_75422516 1.71 ENSMUST00000149727.8
ENSMUST00000108433.8
ENSMUST00000042561.14
ENSMUST00000143035.8
solute carrier family 43, member 2
chr1_-_181670599 1.69 ENSMUST00000193030.6
lamin B receptor
chr2_+_120331693 1.59 ENSMUST00000141181.9
calpain 3
chr16_-_22084700 1.51 ENSMUST00000161286.8
transformer 2 beta
chr19_-_5974825 1.48 ENSMUST00000055458.6
CDC42 effector protein (Rho GTPase binding) 2
chr11_-_78074377 1.48 ENSMUST00000102483.5
ribosomal protein L23A
chr11_-_55310724 1.45 ENSMUST00000108858.8
ENSMUST00000141530.2
secreted acidic cysteine rich glycoprotein
chr3_+_90383425 1.45 ENSMUST00000001042.10
interleukin enhancer binding factor 2
chr3_-_96201248 1.44 ENSMUST00000029748.8
Fc receptor, IgG, high affinity I
chr1_+_130659700 1.43 ENSMUST00000039323.8
expressed sequence AA986860
chr10_-_128462616 1.41 ENSMUST00000026420.7
ribosomal protein S26
chr16_+_97157934 1.36 ENSMUST00000047275.8
beta-site APP-cleaving enzyme 2
chr12_-_15866763 1.35 ENSMUST00000020922.8
ENSMUST00000221215.2
ENSMUST00000221518.2
tribbles pseudokinase 2
chr8_+_106331866 1.34 ENSMUST00000043531.10
RHO family interacting cell polarization regulator 1
chr16_-_23709564 1.34 ENSMUST00000004480.5
somatostatin
chr2_-_148285450 1.33 ENSMUST00000099269.4
CD93 antigen
chr6_+_57679621 1.30 ENSMUST00000050077.15
LanC (bacterial lantibiotic synthetase component C)-like 2
chr2_+_29236815 1.27 ENSMUST00000028139.11
ENSMUST00000113830.11
mediator complex subunit 27
chr4_-_116982804 1.26 ENSMUST00000183310.2
BTB (POZ) domain containing 19
chr2_+_120331784 1.25 ENSMUST00000151342.3
calpain 3
chr2_-_113678945 1.25 ENSMUST00000110949.9
Rho GTPase activating protein 11A
chr4_+_116565784 1.24 ENSMUST00000138305.8
ENSMUST00000125671.8
ENSMUST00000130828.8
coiled-coil domain containing 163
chrX_+_162694397 1.24 ENSMUST00000140845.2
adaptor-related protein complex 1, sigma 2 subunit
chr11_+_75422925 1.20 ENSMUST00000169547.9
solute carrier family 43, member 2
chr2_-_14060774 1.16 ENSMUST00000114753.8
ENSMUST00000091429.12
3-hydroxyacyl-CoA dehydratase 1
chr15_+_6451721 1.13 ENSMUST00000163082.2
disabled 2, mitogen-responsive phosphoprotein
chr4_+_116565706 1.13 ENSMUST00000030452.13
ENSMUST00000106462.9
coiled-coil domain containing 163
chr6_+_57679455 1.13 ENSMUST00000072954.8
LanC (bacterial lantibiotic synthetase component C)-like 2
chr2_-_14060840 1.11 ENSMUST00000074854.9
3-hydroxyacyl-CoA dehydratase 1
chr7_+_28050077 1.09 ENSMUST00000082134.6
ribosomal protein S16
chr18_+_42669322 1.06 ENSMUST00000236418.2
transcription elongation regulator 1 (CA150)
chr11_+_68393845 1.04 ENSMUST00000102613.8
ENSMUST00000060441.7
phosphoinositide-3-kinase regulatory subunit 5
chr2_+_31578537 1.03 ENSMUST00000075759.13
c-abl oncogene 1, non-receptor tyrosine kinase
chr6_-_87510200 1.03 ENSMUST00000113637.9
ENSMUST00000071024.7
Rho GTPase activating protein 25
chr1_+_171668173 1.02 ENSMUST00000136479.8
CD84 antigen
chr9_+_86625694 1.02 ENSMUST00000179574.2
ENSMUST00000036426.13
protease, serine 35
chr5_+_31212165 1.00 ENSMUST00000202795.4
ENSMUST00000201182.4
ENSMUST00000200953.4
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chrX_+_133657312 0.99 ENSMUST00000081834.10
ENSMUST00000086880.11
ENSMUST00000086884.5
armadillo repeat containing, X-linked 3
chr11_+_101136821 0.98 ENSMUST00000129680.8
receptor (calcitonin) activity modifying protein 2
chr4_+_130202388 0.98 ENSMUST00000070532.8
fatty acid binding protein 3, muscle and heart
chr13_-_41513215 0.97 ENSMUST00000224803.2
neural precursor cell expressed, developmentally down-regulated gene 9
chr19_+_12647803 0.97 ENSMUST00000207341.3
ENSMUST00000208494.3
ENSMUST00000208657.3
olfactory receptor 1442
chr13_+_43938251 0.95 ENSMUST00000015540.4
CD83 antigen
chr14_-_56472102 0.94 ENSMUST00000015585.4
granzyme C
chr5_+_31212110 0.93 ENSMUST00000013773.12
ENSMUST00000201838.4
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr5_-_140368482 0.92 ENSMUST00000196566.5
sorting nexin 8
chr4_+_116565819 0.90 ENSMUST00000106463.8
coiled-coil domain containing 163
chr10_+_80905869 0.88 ENSMUST00000005057.7
thimet oligopeptidase 1
chr10_-_79940168 0.86 ENSMUST00000219260.2
strawberry notch 2
chr14_-_22039543 0.85 ENSMUST00000043409.9
zinc finger protein 503
chr1_-_44157916 0.84 ENSMUST00000027213.14
ENSMUST00000065767.9
protein O-glucosyltransferase 2
chr17_-_7639378 0.82 ENSMUST00000231397.2
predicted gene, 49630
chr16_-_56533179 0.81 ENSMUST00000136394.8
Trk-fused gene
chr8_-_85414528 0.81 ENSMUST00000001975.6
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr2_-_73284262 0.80 ENSMUST00000102679.8
WAS/WASL interacting protein family, member 1
chr3_+_153549846 0.79 ENSMUST00000044089.4
ankyrin repeat and SOCS box-containing 17
chr3_+_14706781 0.71 ENSMUST00000029071.9
carbonic anhydrase 13
chr15_-_81810349 0.71 ENSMUST00000023113.7
polymerase (RNA) III (DNA directed) polypeptide H
chr6_-_101354858 0.70 ENSMUST00000075994.11
PDZ domain containing RING finger 3
chr12_-_57244096 0.70 ENSMUST00000044634.12
solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21
chr6_-_141719536 0.68 ENSMUST00000148411.2
predicted gene 5724
chr7_+_44465353 0.68 ENSMUST00000208626.2
ENSMUST00000057195.17
nucleoporin 62
chr15_-_93417380 0.68 ENSMUST00000109255.3
prickle planar cell polarity protein 1
chr5_-_5315968 0.67 ENSMUST00000115451.8
ENSMUST00000115452.8
ENSMUST00000131392.8
cyclin-dependent kinase 14
chr9_-_49710190 0.67 ENSMUST00000114476.8
ENSMUST00000193547.6
neural cell adhesion molecule 1
chr19_+_29229147 0.67 ENSMUST00000025705.7
ENSMUST00000065796.10
ENSMUST00000236990.2
Janus kinase 2
chr9_+_53757448 0.66 ENSMUST00000048485.7
sarcolipin
chr11_+_96242422 0.64 ENSMUST00000100523.7
homeobox B2
chr14_-_104760051 0.63 ENSMUST00000022716.4
ENSMUST00000228448.2
ENSMUST00000227640.2
ORC ubiquitin ligase 1
chr7_+_44465806 0.62 ENSMUST00000207103.2
ENSMUST00000118125.9
nucleoporin 62
interleukin 4 induced 1
chr18_-_38417390 0.62 ENSMUST00000025311.8
protocadherin 12
chr19_-_8690330 0.57 ENSMUST00000206598.2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr7_+_80764564 0.57 ENSMUST00000119083.2
solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
chr14_-_55950939 0.56 ENSMUST00000168729.8
ENSMUST00000228123.2
ENSMUST00000178034.9
transglutaminase 1, K polypeptide
chr1_+_88154727 0.55 ENSMUST00000061013.13
ENSMUST00000113130.8
maestro heat-like repeat family member 2A
chr5_+_117501557 0.55 ENSMUST00000111959.2
WD repeat and SOCS box-containing 2
chr18_-_15536747 0.55 ENSMUST00000079081.8
aquaporin 4
chr4_-_149747644 0.54 ENSMUST00000105689.8
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr7_+_80764547 0.54 ENSMUST00000026820.11
solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
chr18_-_36859732 0.53 ENSMUST00000061829.8
CD14 antigen
chr6_+_48695535 0.53 ENSMUST00000127537.6
ENSMUST00000052503.8
predicted gene, 28053
GTPase, IMAP family member 7
chr8_-_106427696 0.51 ENSMUST00000042608.8
adrenocortical dysplasia
chr7_+_44465714 0.47 ENSMUST00000208172.2
nucleoporin 62
chr18_+_32970278 0.46 ENSMUST00000053663.11
WD repeat domain 36
chr3_-_8988854 0.46 ENSMUST00000042148.6
mitochondrial ribosomal protein S28
chr9_-_49710058 0.46 ENSMUST00000192584.2
ENSMUST00000166811.9
neural cell adhesion molecule 1
chr7_+_88079534 0.43 ENSMUST00000208478.2
RAB38, member RAS oncogene family
chr5_+_21577640 0.42 ENSMUST00000035799.6
fibrinogen-like protein 2
chr18_-_38417444 0.41 ENSMUST00000194012.2
protocadherin 12
chr1_+_120048890 0.41 ENSMUST00000027637.13
ENSMUST00000112644.9
ENSMUST00000056038.15
RIKEN cDNA 3110009E18 gene
chr18_+_32970363 0.39 ENSMUST00000166214.9
WD repeat domain 36
chr11_+_76297969 0.38 ENSMUST00000021203.7
ENSMUST00000152183.2
translocase of inner mitochondrial membrane 22
chr9_+_74959259 0.38 ENSMUST00000170310.2
ENSMUST00000166549.2
cAMP-regulated phosphoprotein 19
chr5_+_8710059 0.36 ENSMUST00000047753.5
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
chr8_-_85414220 0.34 ENSMUST00000238449.2
ENSMUST00000238687.2
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr3_-_116601451 0.31 ENSMUST00000159670.3
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chr3_+_67799510 0.30 ENSMUST00000063263.5
ENSMUST00000182006.4
IQ motif containing J
Iqcj and Schip1 fusion protein
chr6_+_127430668 0.30 ENSMUST00000039680.7
poly (ADP-ribose) polymerase family, member 11
chr14_+_3576275 0.30 ENSMUST00000151926.8
ubiquitin-conjugating enzyme E2E 2
chr11_+_75422953 0.30 ENSMUST00000127226.3
solute carrier family 43, member 2
chr19_+_3818112 0.29 ENSMUST00000005518.16
ENSMUST00000237440.2
ENSMUST00000152935.8
ENSMUST00000176262.8
ENSMUST00000176407.8
ENSMUST00000176926.8
ENSMUST00000176512.8
lysine methyltransferase 5B
chr7_+_127160751 0.28 ENSMUST00000190278.3
transmembrane protein 265
chr9_+_38288382 0.28 ENSMUST00000214865.2
olfactory receptor 251
chr6_+_149226891 0.26 ENSMUST00000189837.2
retroelement silencing factor 1
chr5_-_6926523 0.26 ENSMUST00000164784.2
zinc finger protein 804B
chr9_+_100956734 0.25 ENSMUST00000085177.5
MSL complex subunit 2
chr10_-_100425067 0.23 ENSMUST00000218821.2
ENSMUST00000054471.10
RIKEN cDNA 4930430F08 gene
chr2_+_118730823 0.22 ENSMUST00000151162.2
bromo adjacent homology domain containing 1
chr1_-_160134873 0.21 ENSMUST00000193185.6
RAB GTPase activating protein 1-like
chr18_+_24338729 0.19 ENSMUST00000170243.8
polypeptide N-acetylgalactosaminyltransferase 1
chr14_+_76082533 0.18 ENSMUST00000110894.9
tumor protein, translationally-controlled 1
chr5_+_90708962 0.18 ENSMUST00000094615.8
ENSMUST00000200765.2
albumin superfamily member 1
chr4_+_116565898 0.18 ENSMUST00000135499.8
coiled-coil domain containing 163
chr10_-_51507527 0.18 ENSMUST00000219286.2
ENSMUST00000020062.4
ENSMUST00000218684.2
G protein-coupled receptor, family C, group 6, member A
chr5_-_125201872 0.18 ENSMUST00000055256.14
nuclear receptor co-repressor 2
chr6_+_38358404 0.18 ENSMUST00000162554.8
ENSMUST00000161751.8
tetratricopeptide repeat domain 26
chr4_-_43454600 0.17 ENSMUST00000098105.4
ENSMUST00000098104.10
ENSMUST00000030179.11
CD72 antigen
chr13_-_77283534 0.17 ENSMUST00000159462.3
ENSMUST00000151524.9
SMC5-SMC6 complex localization factor 1
chr14_+_61844899 0.16 ENSMUST00000225582.2
ENSMUST00000051184.10
potassium channel regulator
chr2_-_87466089 0.15 ENSMUST00000090711.3
olfactory receptor 1132
chr11_+_108477903 0.15 ENSMUST00000146912.9
centrosomal protein 112
chr11_+_83743746 0.15 ENSMUST00000108113.3
HNF1 homeobox B
chr18_+_37827413 0.15 ENSMUST00000193414.2
protocadherin gamma subfamily A, 5
chr15_+_51741138 0.14 ENSMUST00000136129.2
UTP23 small subunit processome component
chr7_-_44465998 0.13 ENSMUST00000209072.2
ENSMUST00000047356.11
activating transcription factor 5
chr6_+_34840057 0.12 ENSMUST00000074949.4
transmembrane protein 140
chr4_+_32982981 0.10 ENSMUST00000098190.10
ENSMUST00000029946.14
Ras-related GTP binding D
chr10_+_126914755 0.09 ENSMUST00000039259.7
ENSMUST00000217941.2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr5_-_88823049 0.08 ENSMUST00000133532.8
ENSMUST00000150438.2
G-rich RNA sequence binding factor 1
chr7_+_140462343 0.07 ENSMUST00000163610.9
ENSMUST00000164681.8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr7_+_100435548 0.07 ENSMUST00000216021.2
family with sequence similarity 168, member A
chrX_-_104919201 0.05 ENSMUST00000198209.2
ATRX, chromatin remodeler
chr6_-_78445846 0.05 ENSMUST00000032089.3
regenerating islet-derived 3 gamma
chr9_+_43978290 0.05 ENSMUST00000034508.14
ubiquitin specific peptidase 2
chr7_-_103535459 0.04 ENSMUST00000216303.2
olfactory receptor 66
chr18_+_37488174 0.04 ENSMUST00000192867.2
ENSMUST00000051163.3
protocadherin beta 8
chr7_-_65020655 0.03 ENSMUST00000032729.8
tight junction protein 1
chr19_-_11852453 0.03 ENSMUST00000213954.2
ENSMUST00000217617.2
olfactory receptor 1419
chr1_+_37068387 0.02 ENSMUST00000067178.14
ENSMUST00000238500.2
von Willebrand factor A domain containing 3B
chr1_+_179788675 0.02 ENSMUST00000076687.12
ENSMUST00000097450.10
ENSMUST00000212756.2
CDC42 binding protein kinase alpha
chr17_+_37689924 0.01 ENSMUST00000215518.2
olfactory receptor 105, pseudogene
chr7_+_66489465 0.00 ENSMUST00000098382.10
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 14.9 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.9 4.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.8 2.3 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.7 3.7 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.7 2.1 GO:0003294 atrial ventricular junction remodeling(GO:0003294) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.6 2.4 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.6 2.9 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.5 1.4 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.5 1.9 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.4 1.3 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.4 6.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4 1.8 GO:1905171 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.3 1.0 GO:1990051 negative regulation of phospholipase C activity(GO:1900275) activation of protein kinase C activity(GO:1990051)
0.3 1.3 GO:2001107 negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.3 1.8 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.3 1.1 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.3 1.1 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.3 1.9 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.3 0.5 GO:0071725 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.3 3.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.3 5.9 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 2.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.7 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.2 1.0 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.2 0.7 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.2 0.7 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.2 2.4 GO:0030916 otic vesicle formation(GO:0030916)
0.2 0.9 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.2 0.6 GO:0021570 rhombomere 4 development(GO:0021570)
0.2 1.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.2 0.5 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.2 1.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 1.0 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.7 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.6 GO:0060356 leucine import(GO:0060356)
0.1 0.5 GO:0070295 renal water absorption(GO:0070295)
0.1 1.8 GO:0015809 arginine transport(GO:0015809)
0.1 1.7 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 1.9 GO:0006857 oligopeptide transport(GO:0006857)
0.1 1.0 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 6.9 GO:0043029 T cell homeostasis(GO:0043029)
0.1 1.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 2.3 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 0.4 GO:2001025 positive regulation of response to drug(GO:2001025)
0.1 0.7 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.1 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.2 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.4 GO:0090383 platelet dense granule organization(GO:0060155) phagosome acidification(GO:0090383) melanosome assembly(GO:1903232)
0.1 0.5 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 2.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.6 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.2 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 3.2 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.2 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.0 5.5 GO:0043627 response to estrogen(GO:0043627)
0.0 1.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0061228 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.0 1.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 1.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:1990166 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.0 1.4 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 2.5 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.0 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 1.0 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 1.2 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0044247 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 0.9 GO:0001895 retina homeostasis(GO:0001895)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.8 GO:0044194 cytolytic granule(GO:0044194)
0.9 14.9 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.6 1.7 GO:0070557 PCNA-p21 complex(GO:0070557)
0.4 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 6.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 1.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 1.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 1.0 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 1.8 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.7 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.9 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 2.0 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 1.5 GO:0031932 TORC2 complex(GO:0031932)
0.1 2.1 GO:0005922 connexon complex(GO:0005922)
0.1 1.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) nuclear lamina(GO:0005652) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 4.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 0.5 GO:0070187 telosome(GO:0070187)
0.0 1.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 7.9 GO:0000776 kinetochore(GO:0000776)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 2.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 3.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.9 GO:0030904 retromer complex(GO:0030904)
0.0 3.1 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 3.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.3 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.8 2.3 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.7 6.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.6 1.9 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.6 1.9 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298) CCR1 chemokine receptor binding(GO:0031726)
0.6 1.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.5 2.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.5 5.9 GO:0008061 chitin binding(GO:0008061)
0.4 1.1 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.2 1.8 GO:0051425 PTB domain binding(GO:0051425)
0.2 1.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 14.9 GO:0004601 peroxidase activity(GO:0004601)
0.2 1.4 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.8 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 2.8 GO:0031432 titin binding(GO:0031432)
0.2 1.4 GO:0001515 opioid peptide activity(GO:0001515)
0.2 1.3 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.0 GO:0097643 amylin receptor activity(GO:0097643)
0.1 1.6 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.4 GO:0036461 BLOC-2 complex binding(GO:0036461)
0.1 0.7 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.4 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 1.6 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 2.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.4 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.1 1.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.3 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.1 0.5 GO:0071723 lipopeptide binding(GO:0071723)
0.1 5.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.0 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 3.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 3.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.5 GO:0015288 porin activity(GO:0015288)
0.1 1.0 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 1.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 3.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.5 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 2.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.7 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0 1.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 15.0 PID IL23 PATHWAY IL23-mediated signaling events
0.2 1.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 8.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 3.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 6.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.9 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.0 PID ATM PATHWAY ATM pathway
0.0 1.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 6.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 7.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 7.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 0.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 2.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 2.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.1 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 3.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+