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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Tal1

Z-value: 7.19

Motif logo

Transcription factors associated with Tal1

Gene Symbol Gene ID Gene Info
ENSMUSG00000028717.13 Tal1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tal1mm39_v1_chr4_+_114916703_1149167590.979.3e-23Click!

Activity profile of Tal1 motif

Sorted Z-values of Tal1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tal1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_-_103159892 90.35 ENSMUST00000133600.8
ENSMUST00000134554.2
ENSMUST00000156927.8
nuclear factor, erythroid derived 2
chr15_-_103160082 82.43 ENSMUST00000149111.8
ENSMUST00000132836.8
nuclear factor, erythroid derived 2
chr17_+_41121979 70.59 ENSMUST00000024721.8
ENSMUST00000233740.2
Rhesus blood group-associated A glycoprotein
chr1_-_132295617 59.00 ENSMUST00000142609.8
transmembrane and coiled-coil domains 2
chr17_+_37180437 56.90 ENSMUST00000060524.11
tripartite motif-containing 10
chr4_+_134591847 56.23 ENSMUST00000030627.8
Rh blood group, D antigen
chr6_+_86055018 52.17 ENSMUST00000205034.3
ENSMUST00000203724.3
adducin 2 (beta)
chr4_-_119047202 51.84 ENSMUST00000239029.2
ENSMUST00000138395.9
ENSMUST00000156746.3
erythroblast membrane-associated protein
chr8_+_81220410 46.28 ENSMUST00000063359.8
glycophorin A
chr1_+_131566044 45.81 ENSMUST00000073350.13
cathepsin E
chr17_-_26417982 45.61 ENSMUST00000142410.2
ENSMUST00000120333.8
ENSMUST00000039113.14
protein disulfide isomerase associated 2
chr5_+_90920294 45.33 ENSMUST00000031320.8
platelet factor 4
chr14_-_44112974 44.63 ENSMUST00000179200.2
eosinophil-associated, ribonuclease A family, member 1
chr1_+_131566223 43.76 ENSMUST00000112411.2
cathepsin E
chr8_+_85428059 43.12 ENSMUST00000238364.2
ENSMUST00000238562.2
ENSMUST00000037165.6
lymphoblastomic leukemia 1
chr4_-_119047167 42.52 ENSMUST00000030396.15
erythroblast membrane-associated protein
chr9_-_21874802 42.46 ENSMUST00000006397.7
erythropoietin receptor
chr6_+_86055048 42.00 ENSMUST00000032069.8
adducin 2 (beta)
chr5_+_90920353 41.47 ENSMUST00000202625.2
platelet factor 4
chrX_+_8137881 39.55 ENSMUST00000115590.2
solute carrier family 38, member 5
chr7_-_103502404 36.52 ENSMUST00000033229.5
hemoglobin Y, beta-like embryonic chain
chr1_+_174000304 36.46 ENSMUST00000027817.8
spectrin alpha, erythrocytic 1
chr14_-_44057096 36.33 ENSMUST00000100691.4
eosinophil-associated, ribonuclease A family, member 1
chr11_-_79971750 36.12 ENSMUST00000103233.10
ENSMUST00000061283.15
cytokine receptor-like factor 3
chr10_-_62178453 35.31 ENSMUST00000143179.2
ENSMUST00000130422.8
hexokinase 1
chr4_-_119047180 33.51 ENSMUST00000150864.3
ENSMUST00000141227.9
erythroblast membrane-associated protein
chr4_-_119047146 33.38 ENSMUST00000124626.9
erythroblast membrane-associated protein
chr7_+_99243812 32.04 ENSMUST00000162290.2
arrestin, beta 1
chr9_+_20940669 31.51 ENSMUST00000001040.7
ENSMUST00000215077.2
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr14_+_52091156 31.12 ENSMUST00000169070.2
ENSMUST00000074477.7
eosinophil-associated, ribonuclease A family, member 6
chr16_-_18440388 30.89 ENSMUST00000167388.3
glycoprotein Ib, beta polypeptide
chr8_+_23525101 28.77 ENSMUST00000117662.8
ENSMUST00000117296.8
ENSMUST00000141784.9
ankyrin 1, erythroid
chr17_+_31427023 26.79 ENSMUST00000173776.2
ENSMUST00000048656.15
ubiquitin associated and SH3 domain containing, A
chr1_-_181669891 26.29 ENSMUST00000193028.2
ENSMUST00000191878.6
ENSMUST00000005003.12
lamin B receptor
chr11_+_32226400 25.67 ENSMUST00000020531.9
hemoglobin X, alpha-like embryonic chain in Hba complex
chr6_+_41331039 24.75 ENSMUST00000072103.7
trypsin 10
chr2_+_84669739 22.54 ENSMUST00000146816.8
ENSMUST00000028469.14
solute carrier family 43, member 1
chr15_+_80507671 22.36 ENSMUST00000043149.9
GRB2-related adaptor protein 2
chr15_+_78810919 22.09 ENSMUST00000089377.6
lectin, galactose binding, soluble 1
chr11_+_58808830 21.99 ENSMUST00000020792.12
ENSMUST00000108818.4
butyrophilin-like 10
chr17_-_33932346 21.32 ENSMUST00000173392.2
membrane associated ring-CH-type finger 2
chrX_-_106446928 21.11 ENSMUST00000033591.6
integral membrane protein 2A
chr6_-_136834725 21.04 ENSMUST00000032341.3
ADP-ribosyltransferase 4
chr8_+_95712151 20.93 ENSMUST00000212799.2
adhesion G protein-coupled receptor G1
chr11_-_102360664 20.34 ENSMUST00000103086.4
integrin alpha 2b
chr4_+_132701413 19.91 ENSMUST00000030693.13
FGR proto-oncogene, Src family tyrosine kinase
chr12_+_111387978 19.66 ENSMUST00000222897.2
exocyst complex component 3-like 4
chr7_+_110372860 19.65 ENSMUST00000143786.2
adenosine monophosphate deaminase 3
chr7_-_4400704 19.57 ENSMUST00000108590.4
ENSMUST00000206928.2
glycoprotein 6 (platelet)
chr3_-_14873406 19.22 ENSMUST00000181860.8
ENSMUST00000144327.3
carbonic anhydrase 1
chr8_-_86091946 19.18 ENSMUST00000034133.14
myosin light chain kinase 3
chr11_+_32226893 19.16 ENSMUST00000145569.2
hemoglobin X, alpha-like embryonic chain in Hba complex
chr6_+_41435846 19.05 ENSMUST00000031910.8
protease, serine 1 (trypsin 1)
chrX_+_92718695 18.02 ENSMUST00000045898.4
phosphate cytidylyltransferase 1, choline, beta isoform
chr9_+_107828136 17.26 ENSMUST00000049348.9
ENSMUST00000194271.2
TRAF-interacting protein
chr14_+_26722319 17.18 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr17_+_35133435 16.76 ENSMUST00000007249.15
solute carrier family 44, member 4
chr8_+_85428391 16.50 ENSMUST00000238338.2
lymphoblastomic leukemia 1
chr9_-_110886306 16.45 ENSMUST00000195968.2
ENSMUST00000111888.3
chemokine (C-C motif) receptor-like 2
chr14_+_44340111 16.45 ENSMUST00000074839.7
eosinophil-associated, ribonuclease A family, member 2
chr16_+_49620883 16.40 ENSMUST00000229640.2
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr2_-_153083322 15.96 ENSMUST00000056924.14
pleiomorphic adenoma gene-like 2
chr5_-_24235295 15.75 ENSMUST00000101513.9
family with sequence similarity 126, member A
chr10_-_93727003 15.25 ENSMUST00000180840.8
methionine aminopeptidase 2
chr11_+_117673107 14.67 ENSMUST00000050874.14
ENSMUST00000106334.9
transmembrane channel-like gene family 8
chr4_-_155012643 13.63 ENSMUST00000123514.8
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
chr2_-_156848923 13.25 ENSMUST00000146413.8
ENSMUST00000103129.9
ENSMUST00000103130.8
DSN1 homolog, MIS12 kinetochore complex component
chr3_-_98800524 13.06 ENSMUST00000029464.9
hydroxyacid oxidase 2
chr5_-_24235646 13.02 ENSMUST00000197617.5
ENSMUST00000030849.13
family with sequence similarity 126, member A
chrX_+_55493325 12.80 ENSMUST00000079663.7
predicted gene 2174
chr19_+_58748132 12.76 ENSMUST00000026081.5
pancreatic lipase-related protein 2
chr17_+_34824827 12.53 ENSMUST00000037489.15
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr16_-_19801781 12.37 ENSMUST00000058839.10
kelch-like 6
chr4_-_41464816 12.14 ENSMUST00000108055.9
ENSMUST00000154535.8
ENSMUST00000030148.6
kinesin family member 24
chr7_+_97492124 12.10 ENSMUST00000033040.12
p21 (RAC1) activated kinase 1
chr6_-_25809209 12.08 ENSMUST00000115330.8
protection of telomeres 1A
chr6_+_30541581 11.90 ENSMUST00000096066.5
carboxypeptidase A2, pancreatic
chr2_-_153067297 11.81 ENSMUST00000099194.4
TSPY-like 3
chr5_+_137628377 11.55 ENSMUST00000175968.8
leucine-rich repeats and calponin homology (CH) domain containing 4
chr11_+_58839716 11.18 ENSMUST00000078267.5
H2B.U histone 2
chr15_+_57849269 10.64 ENSMUST00000050374.3
family with sequence similarity 83, member A
chr10_-_128462616 10.35 ENSMUST00000026420.7
ribosomal protein S26
chr11_+_117673198 10.08 ENSMUST00000117781.8
transmembrane channel-like gene family 8
chr10_+_13376745 10.07 ENSMUST00000060212.13
ENSMUST00000121465.3
fucosidase, alpha-L- 2, plasma
chr16_+_58490625 9.98 ENSMUST00000060077.7
coproporphyrinogen oxidase
chr2_-_102731691 9.58 ENSMUST00000111192.3
ENSMUST00000111190.9
ENSMUST00000111198.9
ENSMUST00000111191.9
ENSMUST00000060516.14
ENSMUST00000099673.9
ENSMUST00000005218.15
ENSMUST00000111194.8
CD44 antigen
chr11_+_94827050 9.57 ENSMUST00000001547.8
collagen, type I, alpha 1
chr14_+_22069877 9.55 ENSMUST00000161249.8
ENSMUST00000159777.8
ENSMUST00000162540.2
leucine rich melanocyte differentiation associated
chr10_-_80257681 9.46 ENSMUST00000156244.2
transcription factor 3
chr8_-_78244412 9.10 ENSMUST00000210922.2
ENSMUST00000210519.2
Rho GTPase activating protein 10
chrX_-_137985960 8.86 ENSMUST00000033626.15
ENSMUST00000060824.4
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr4_-_56802266 8.80 ENSMUST00000030140.3
elongator complex protein 1
chr4_-_59438633 8.62 ENSMUST00000040166.14
ENSMUST00000107544.2
sushi domain containing 1
chr15_-_74635423 8.56 ENSMUST00000040404.8
lymphocyte antigen 6 complex, locus D
chr10_+_97400990 8.36 ENSMUST00000038160.6
lumican
chr9_-_110886576 8.24 ENSMUST00000199839.5
chemokine (C-C motif) receptor-like 2
chr6_-_25809188 8.20 ENSMUST00000115327.8
protection of telomeres 1A
chr13_-_95661726 8.18 ENSMUST00000022185.10
coagulation factor II (thrombin) receptor-like 1
chr6_+_41279199 7.99 ENSMUST00000031913.5
trypsin 4
chr5_-_137145030 7.95 ENSMUST00000054384.6
ENSMUST00000152207.2
tripartite motif-containing 56
chr11_-_117673008 7.90 ENSMUST00000152304.3
transmembrane channel-like gene family 6
chrX_-_137985979 7.86 ENSMUST00000152457.2
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr6_-_34294377 7.67 ENSMUST00000154655.2
ENSMUST00000102980.11
aldo-keto reductase family 1, member B3 (aldose reductase)
chr2_+_29951766 7.63 ENSMUST00000149578.8
SET nuclear oncogene
chr9_+_66257747 7.48 ENSMUST00000042824.13
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr4_+_132262853 7.23 ENSMUST00000094657.10
ENSMUST00000105940.10
ENSMUST00000105939.10
ENSMUST00000150207.8
DnaJ heat shock protein family (Hsp40) member C8
chr6_+_67586695 7.18 ENSMUST00000103303.3
immunoglobulin kappa variable 1-135
chr13_+_49835576 7.02 ENSMUST00000165316.8
ENSMUST00000047363.14
isoleucine-tRNA synthetase
chr2_+_126922156 6.99 ENSMUST00000142737.3
biliverdin reductase A
chr1_-_23961379 6.85 ENSMUST00000027339.14
small ArfGAP 1
chr7_-_115445315 6.76 ENSMUST00000166207.3
SRY (sex determining region Y)-box 6
chr7_+_16807965 6.62 ENSMUST00000071399.13
ENSMUST00000118367.3
pregnancy specific glycoprotein 16
chr3_+_89043879 6.53 ENSMUST00000107482.10
ENSMUST00000127058.2
pyruvate kinase liver and red blood cell
chr3_+_89043440 6.50 ENSMUST00000047111.13
pyruvate kinase liver and red blood cell
chr13_+_49835667 6.46 ENSMUST00000172254.3
isoleucine-tRNA synthetase
chr5_+_115983292 6.40 ENSMUST00000137952.8
ENSMUST00000148245.8
citron
chr4_+_56802338 6.30 ENSMUST00000045368.12
actin binding transcription modulator
chr2_+_29951859 5.92 ENSMUST00000102866.10
SET nuclear oncogene
chr11_-_78067446 5.85 ENSMUST00000148154.3
ENSMUST00000017549.13
NIMA (never in mitosis gene a)-related expressed kinase 8
chr7_+_142052569 5.83 ENSMUST00000078497.15
ENSMUST00000105953.10
ENSMUST00000179658.8
ENSMUST00000105954.10
ENSMUST00000105952.10
ENSMUST00000105955.8
ENSMUST00000074187.13
ENSMUST00000169299.9
ENSMUST00000105957.10
ENSMUST00000180152.8
ENSMUST00000105950.11
ENSMUST00000105958.10
ENSMUST00000105949.8
troponin T3, skeletal, fast
chr11_+_117672902 5.60 ENSMUST00000127080.9
transmembrane channel-like gene family 8
chr19_+_4608836 5.48 ENSMUST00000236457.2
pyruvate carboxylase
chr14_+_22069709 5.47 ENSMUST00000075639.11
leucine rich melanocyte differentiation associated
chr9_+_99125420 5.31 ENSMUST00000185799.7
ENSMUST00000093795.10
ENSMUST00000190715.7
ENSMUST00000191335.7
ENSMUST00000190078.7
centrosomal protein 70
chr3_+_116653113 5.11 ENSMUST00000040260.11
ferric-chelate reductase 1
chr6_+_117840031 5.00 ENSMUST00000172088.8
ENSMUST00000079405.15
zinc finger protein 239
chr14_+_51366512 4.94 ENSMUST00000095923.4
ribonuclease, RNase A family, 6
chr6_-_87567690 4.82 ENSMUST00000203636.2
ENSMUST00000050887.9
ENSMUST00000204682.3
prokineticin receptor 1
chr10_-_117060377 4.81 ENSMUST00000020382.8
YEATS domain containing 4
chr9_+_59198829 4.78 ENSMUST00000217570.2
ENSMUST00000026266.9
ADP-dependent glucokinase
chr9_-_106764627 4.42 ENSMUST00000055843.9
RNA binding motif protein 15B
chr19_-_29344694 4.41 ENSMUST00000138051.2
plasminogen receptor, C-terminal lysine transmembrane protein
chr8_+_105066924 4.35 ENSMUST00000212081.2
CKLF-like MARVEL transmembrane domain containing 3
chr17_-_26080429 4.34 ENSMUST00000079461.15
ENSMUST00000176923.9
WD repeat domain 90
chr7_+_45683122 4.08 ENSMUST00000033121.7
nodal modulator 1
chr19_+_29344846 4.06 ENSMUST00000016640.8
CD274 antigen
chr1_-_171476495 3.94 ENSMUST00000194791.2
ENSMUST00000192024.6
SLAM family member 7
chr1_-_171476559 3.84 ENSMUST00000111276.9
ENSMUST00000194531.6
SLAM family member 7
chr4_+_41569775 3.81 ENSMUST00000102963.10
dynein axonemal intermediate chain 1
chr8_+_108162985 3.81 ENSMUST00000166615.3
ENSMUST00000213097.2
ENSMUST00000212205.2
WW domain containing E3 ubiquitin protein ligase 2
chr1_-_52271455 3.73 ENSMUST00000114512.8
glutaminase
chr3_+_88528743 3.66 ENSMUST00000170653.9
ENSMUST00000177303.8
rho/rac guanine nucleotide exchange factor (GEF) 2
chr18_-_36859732 3.57 ENSMUST00000061829.8
CD14 antigen
chr6_-_38331482 3.46 ENSMUST00000031850.10
ENSMUST00000114898.3
zinc finger CCCH type, antiviral 1
chr2_-_120561983 3.25 ENSMUST00000110701.8
ENSMUST00000110700.2
congenital dyserythropoietic anemia, type I (human)
chr7_+_4467730 3.19 ENSMUST00000086372.8
ENSMUST00000169820.8
ENSMUST00000163893.8
ENSMUST00000170635.2
EPS8-like 1
chr13_-_13568106 3.13 ENSMUST00000021738.10
ENSMUST00000220628.2
G protein-coupled receptor 137B
chr3_-_83749036 3.08 ENSMUST00000029623.11
toll-like receptor 2
chr14_-_44161016 2.99 ENSMUST00000159175.2
eosinophil-associated, ribonuclease A family, member 10
chr12_-_114477427 2.97 ENSMUST00000191803.2
immunoglobulin heavy variable V1-5
chr2_+_181506130 2.95 ENSMUST00000039551.9
polymerase (RNA) III (DNA directed) polypeptide K
chr5_-_137202790 2.82 ENSMUST00000041226.11
mucin 3, intestinal
chr2_-_152857239 2.82 ENSMUST00000028972.9
p53 and DNA damage regulated 1
chr6_+_125048230 2.75 ENSMUST00000140346.9
ENSMUST00000171989.3
lysophosphatidic acid receptor 5
chr9_-_65734826 2.75 ENSMUST00000159109.2
zinc finger protein 609
chr9_+_32547529 2.62 ENSMUST00000238819.2
E26 avian leukemia oncogene 1, 5' domain
chr5_+_123482496 2.56 ENSMUST00000031391.9
ENSMUST00000117971.2
B cell CLL/lymphoma 7A
chr13_-_74882328 2.55 ENSMUST00000223309.2
calpastatin
chr7_+_139900771 2.53 ENSMUST00000214594.2
olfactory receptor 525
chr11_+_65698001 2.30 ENSMUST00000071465.9
ENSMUST00000018491.8
zinc finger with KRAB and SCAN domains 6
chr1_-_74076279 2.05 ENSMUST00000187281.7
tensin 1
chr2_+_143874979 2.04 ENSMUST00000037722.9
ENSMUST00000110032.2
BANF family member 2
chr1_+_171386752 2.01 ENSMUST00000004829.13
CD244 molecule A
chr15_+_12205095 2.01 ENSMUST00000038172.16
myotubularin related protein 12
chr1_-_131161312 1.93 ENSMUST00000212202.2
Ras association (RalGDS/AF-6) domain family member 5
chr2_-_6726417 1.91 ENSMUST00000142941.8
ENSMUST00000150624.9
ENSMUST00000100429.11
ENSMUST00000182879.8
CUGBP, Elav-like family member 2
chr17_-_13350642 1.90 ENSMUST00000232960.2
ENSMUST00000084966.6
ENSMUST00000233405.2
unc-93 homolog A
chr6_+_17306334 1.79 ENSMUST00000007799.13
ENSMUST00000115456.6
caveolin 1, caveolae protein
chr2_-_166885414 1.69 ENSMUST00000067584.7
zinc finger, NFX1-type containing 1
chr11_+_67090878 1.69 ENSMUST00000124516.8
ENSMUST00000018637.15
ENSMUST00000129018.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr2_-_87504008 1.66 ENSMUST00000213835.2
olfactory receptor 1135
chr14_+_64097739 1.59 ENSMUST00000022528.6
PIN2/TERF1 interacting, telomerase inhibitor 1
chr2_-_20973692 1.57 ENSMUST00000114594.8
Rho GTPase activating protein 21
chr12_-_114528632 1.47 ENSMUST00000195337.2
ENSMUST00000103497.2
immunoglobulin heavy variable V15-2
chr5_-_134205559 1.47 ENSMUST00000076228.3
reculator of chromosome condensation 1 like
chr10_+_42378026 1.47 ENSMUST00000105500.8
ENSMUST00000019939.12
sorting nexin 3
chr12_-_108859123 1.41 ENSMUST00000161154.2
ENSMUST00000161410.8
tryptophanyl-tRNA synthetase
chr12_-_115884332 1.30 ENSMUST00000103548.3
immunoglobulin heavy variable 1-81
chr9_-_105398346 1.26 ENSMUST00000176770.8
ENSMUST00000085133.13
ATPase, Ca++-sequestering
chr10_+_80972089 1.25 ENSMUST00000048128.15
zinc finger and BTB domain containing 7a
chr9_-_21042521 1.18 ENSMUST00000216874.2
ENSMUST00000214454.2
ENSMUST00000214864.2
tyrosine kinase 2
chr10_+_80972368 1.14 ENSMUST00000119606.8
ENSMUST00000146895.2
ENSMUST00000121840.8
zinc finger and BTB domain containing 7a
chr17_-_48739874 1.13 ENSMUST00000046549.5
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr16_+_17328924 1.12 ENSMUST00000232372.2
leucine-zipper-like transcriptional regulator, 1
chr14_+_54713703 1.02 ENSMUST00000164697.8
rad and gem related GTP binding protein 2
chr18_+_89195089 1.01 ENSMUST00000236644.2
ENSMUST00000236828.2
CD226 antigen
chr10_-_129962924 0.94 ENSMUST00000074161.2
olfactory receptor 824
chr7_-_104983311 0.93 ENSMUST00000211006.3
ENSMUST00000216230.2
olfactory receptor 690
chr7_+_97130135 0.79 ENSMUST00000026126.10
integrator complex subunit 4
chr9_+_39932760 0.70 ENSMUST00000215956.3
olfactory receptor 981
chr1_-_173363523 0.68 ENSMUST00000139092.8
interferon activated gene 214
chr8_+_105066980 0.64 ENSMUST00000211885.2
CKLF-like MARVEL transmembrane domain containing 3
chr5_-_53864595 0.64 ENSMUST00000200691.4
cholecystokinin A receptor
chr1_-_44140820 0.63 ENSMUST00000152239.8
testis expressed 30
chr6_+_48624158 0.60 ENSMUST00000203083.3
GTPase, IMAP family member 8
chr4_-_118036827 0.56 ENSMUST00000097911.9
lysine (K)-specific demethylase 4A
chr3_+_98129463 0.52 ENSMUST00000029469.5
regenerating islet-derived family, member 4
chr15_-_34356567 0.51 ENSMUST00000179647.2
RIKEN cDNA 9430069I07 gene
chr6_-_68732577 0.47 ENSMUST00000103332.2
immunoglobulin kappa variable 4-92
chr6_+_48624295 0.46 ENSMUST00000078223.6
ENSMUST00000203509.2
GTPase, IMAP family member 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
31.7 126.8 GO:0072488 ammonium transmembrane transport(GO:0072488)
17.4 86.8 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
11.5 172.8 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
9.0 81.3 GO:0015671 oxygen transport(GO:0015671)
7.4 22.1 GO:0034118 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
5.6 16.8 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
5.6 16.7 GO:0033189 response to vitamin A(GO:0033189)
5.3 16.0 GO:0034378 chylomicron assembly(GO:0034378)
5.1 20.3 GO:0060382 regulation of DNA strand elongation(GO:0060382)
5.0 59.6 GO:0001955 blood vessel maturation(GO:0001955)
4.7 89.6 GO:0016540 protein autoprocessing(GO:0016540)
4.5 13.5 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
4.4 35.3 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
4.0 32.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
3.9 46.3 GO:0047484 regulation of response to osmotic stress(GO:0047484)
3.5 21.1 GO:0002317 plasma cell differentiation(GO:0002317)
3.3 13.2 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
3.2 19.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
3.0 42.5 GO:0061032 visceral serous pericardium development(GO:0061032)
3.0 12.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
2.7 8.2 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
2.7 66.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
2.6 7.7 GO:0090420 hexitol metabolic process(GO:0006059) naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
2.4 9.6 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
2.4 94.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
2.2 39.6 GO:0015816 glycine transport(GO:0015816)
2.2 55.9 GO:0038065 collagen-activated signaling pathway(GO:0038065)
2.0 10.0 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
2.0 19.6 GO:0032264 IMP salvage(GO:0032264)
1.7 65.2 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
1.7 6.6 GO:0071725 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
1.6 16.4 GO:0008228 opsonization(GO:0008228)
1.6 17.2 GO:0030916 otic vesicle formation(GO:0030916)
1.3 13.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.2 9.5 GO:0002326 B cell lineage commitment(GO:0002326)
1.2 19.7 GO:0051601 exocyst localization(GO:0051601)
1.1 10.1 GO:0006004 fucose metabolic process(GO:0006004)
1.1 5.5 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.1 15.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
1.1 15.2 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
1.1 12.8 GO:0019374 galactolipid metabolic process(GO:0019374)
1.0 30.3 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
1.0 8.4 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.9 37.8 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.9 7.0 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.9 19.9 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.9 13.6 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.8 20.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.8 59.0 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.8 6.8 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.7 28.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.7 12.5 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.7 36.1 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.7 22.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.6 11.6 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.6 4.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.6 3.7 GO:0006543 glutamine catabolic process(GO:0006543)
0.6 4.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.5 1.6 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.5 5.0 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.5 22.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.5 3.7 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.4 5.8 GO:0035330 regulation of hippo signaling(GO:0035330)
0.4 7.5 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.4 13.1 GO:0042537 benzene-containing compound metabolic process(GO:0042537)
0.3 19.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.3 15.0 GO:0030318 melanocyte differentiation(GO:0030318)
0.3 2.6 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.3 1.3 GO:0032468 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.3 1.6 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 12.4 GO:0002467 germinal center formation(GO:0002467)
0.3 3.5 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.3 3.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.2 23.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 6.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 6.8 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.2 1.0 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.2 18.7 GO:0070527 platelet aggregation(GO:0070527)
0.2 4.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 12.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 1.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 13.6 GO:0006334 nucleosome assembly(GO:0006334)
0.2 0.6 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.1 2.8 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 2.6 GO:0007343 egg activation(GO:0007343)
0.1 21.1 GO:0007596 blood coagulation(GO:0007596)
0.1 3.2 GO:0031497 chromatin assembly(GO:0031497)
0.1 8.7 GO:0001541 ovarian follicle development(GO:0001541)
0.1 2.7 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 3.0 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 6.0 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.1 1.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 9.5 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.1 5.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 3.8 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 0.2 GO:0051977 lysophospholipid transport(GO:0051977)
0.1 4.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 2.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.6 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 5.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 2.0 GO:1901998 toxin transport(GO:1901998)
0.0 0.8 GO:0016180 snRNA processing(GO:0016180)
0.0 2.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 1.1 GO:0070232 regulation of T cell apoptotic process(GO:0070232)
0.0 15.7 GO:0006935 chemotaxis(GO:0006935)
0.0 0.2 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.9 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
10.2 81.3 GO:0005833 hemoglobin complex(GO:0005833)
6.3 94.2 GO:0008290 F-actin capping protein complex(GO:0008290)
6.1 36.5 GO:0032437 cuticular plate(GO:0032437)
5.7 80.2 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
4.4 13.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
3.2 9.6 GO:0005584 collagen type I trimer(GO:0005584)
2.0 20.3 GO:0070187 telosome(GO:0070187)
1.9 40.2 GO:0031143 pseudopodium(GO:0031143)
1.9 20.9 GO:0097451 glial limiting end-foot(GO:0097451)
1.6 19.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.5 7.7 GO:0097454 Schwann cell microvillus(GO:0097454)
1.5 5.8 GO:0097543 ciliary inversin compartment(GO:0097543)
1.3 26.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
1.1 28.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.0 3.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.9 174.4 GO:0032993 protein-DNA complex(GO:0032993)
0.8 13.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.8 8.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.8 19.7 GO:0000145 exocyst(GO:0000145)
0.8 32.4 GO:0097228 sperm principal piece(GO:0097228)
0.6 9.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.6 12.1 GO:0071437 invadopodium(GO:0071437)
0.6 12.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.5 20.3 GO:0008305 integrin complex(GO:0008305)
0.4 3.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 19.9 GO:0016235 aggresome(GO:0016235)
0.3 2.8 GO:0016272 prefoldin complex(GO:0016272)
0.2 111.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 24.7 GO:0072562 blood microparticle(GO:0072562)
0.2 10.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 4.8 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 2.9 GO:0005861 troponin complex(GO:0005861)
0.1 12.6 GO:0005871 kinesin complex(GO:0005871)
0.1 3.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 13.6 GO:0005811 lipid particle(GO:0005811)
0.1 1.5 GO:0032009 early phagosome(GO:0032009)
0.1 10.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 36.3 GO:0031965 nuclear membrane(GO:0031965)
0.1 7.2 GO:0045171 intercellular bridge(GO:0045171)
0.1 6.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 23.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 18.6 GO:0016324 apical plasma membrane(GO:0016324)
0.1 3.7 GO:0002102 podosome(GO:0002102)
0.1 159.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 11.6 GO:0016605 PML body(GO:0016605)
0.1 52.7 GO:0005768 endosome(GO:0005768)
0.1 1.7 GO:0032982 myosin filament(GO:0032982)
0.1 9.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 81.1 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.0 0.8 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 3.7 GO:0005759 mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
14.5 86.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
10.7 32.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
9.1 36.5 GO:0031721 hemoglobin alpha binding(GO:0031721)
6.8 20.3 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
6.4 44.8 GO:0005344 oxygen transporter activity(GO:0005344)
5.5 22.1 GO:0048030 disaccharide binding(GO:0048030)
5.0 19.9 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
4.6 141.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
4.5 18.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
4.5 13.5 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
4.4 35.3 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
4.1 20.3 GO:0070051 fibrinogen binding(GO:0070051)
3.8 45.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
3.4 10.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
3.3 13.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
2.9 172.8 GO:0050699 WW domain binding(GO:0050699)
2.9 28.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
2.8 39.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
2.7 87.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
2.6 13.0 GO:0004743 pyruvate kinase activity(GO:0004743)
2.4 26.3 GO:0070087 chromo shadow domain binding(GO:0070087)
2.1 19.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
2.0 8.2 GO:0015057 thrombin receptor activity(GO:0015057)
2.0 19.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.9 19.2 GO:0004064 arylesterase activity(GO:0004064)
1.5 21.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.5 16.4 GO:0070053 thrombospondin receptor activity(GO:0070053)
1.4 19.6 GO:0038064 collagen receptor activity(GO:0038064)
1.4 7.0 GO:0004074 biliverdin reductase activity(GO:0004074)
1.4 5.5 GO:0004736 pyruvate carboxylase activity(GO:0004736)
1.3 24.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
1.2 9.5 GO:0070644 vitamin D response element binding(GO:0070644)
1.1 89.3 GO:0030507 spectrin binding(GO:0030507)
1.0 3.1 GO:0042497 triacyl lipopeptide binding(GO:0042497)
1.0 9.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
1.0 130.8 GO:0004540 ribonuclease activity(GO:0004540)
0.9 3.6 GO:0071723 lipopeptide binding(GO:0071723)
0.9 7.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.8 5.8 GO:0030899 calcium-dependent ATPase activity(GO:0030899) troponin I binding(GO:0031013)
0.8 10.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.8 4.8 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.8 12.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.6 5.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.6 3.7 GO:0004359 glutaminase activity(GO:0004359)
0.6 9.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.5 12.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.5 22.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.5 41.4 GO:0005518 collagen binding(GO:0005518)
0.4 3.5 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.4 13.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.4 11.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 2.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.4 1.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.3 15.2 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.3 1.3 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.3 21.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 33.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.3 23.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 1.6 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.3 6.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 1.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2 3.2 GO:0042608 T cell receptor binding(GO:0042608)
0.2 43.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 27.8 GO:0005178 integrin binding(GO:0005178)
0.1 14.6 GO:0042562 hormone binding(GO:0042562)
0.1 3.0 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 1.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 32.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 12.1 GO:0003777 microtubule motor activity(GO:0003777)
0.1 3.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 3.8 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 6.4 GO:0097110 scaffold protein binding(GO:0097110)
0.1 1.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 13.8 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 2.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 56.3 GO:0008270 zinc ion binding(GO:0008270)
0.1 48.7 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 8.3 GO:0000149 SNARE binding(GO:0000149)
0.1 10.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 11.2 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 5.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 14.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 21.9 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 2.0 GO:0019208 phosphatase regulator activity(GO:0019208)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 114.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
1.3 22.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
1.2 31.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.1 40.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.6 12.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.6 14.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.6 9.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.5 29.0 PID EPO PATHWAY EPO signaling pathway
0.5 26.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.5 59.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.5 22.1 PID RAS PATHWAY Regulation of Ras family activation
0.4 37.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 92.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 9.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 8.2 ST GA12 PATHWAY G alpha 12 Pathway
0.2 13.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 6.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 8.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 6.4 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 19.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 3.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.0 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 86.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
2.5 40.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
2.0 76.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
1.2 63.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.1 20.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
1.1 62.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
1.0 159.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.9 34.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.8 32.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.8 8.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.8 4.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.8 9.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.8 19.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.7 16.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.7 19.9 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.7 17.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.7 18.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.6 32.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.6 19.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.6 35.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.5 15.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.5 14.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.4 13.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 3.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.3 9.0 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.3 3.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 3.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 12.3 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.2 10.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 9.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 13.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 8.9 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 1.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 13.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 5.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 3.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK