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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Tbx20

Z-value: 0.52

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Transcription factors associated with Tbx20

Gene Symbol Gene ID Gene Info
Tbx20
ENSMUSG00000031965.16 Tbx20

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx20mm39_v1_chr9_-_24685572_246855990.019.4e-01Click!

Activity profile of Tbx20 motif

Sorted Z-values of Tbx20 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx20

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr8_-_106660470 9.97 ENSMUST00000034368.8
Ctrl
chymotrypsin-like
chr5_-_53864874 1.13 ENSMUST00000031093.5
Cckar
cholecystokinin A receptor
chr8_-_23184070 0.44 ENSMUST00000131767.2
Ikbkb
inhibitor of kappaB kinase beta
chr2_+_122129379 0.25 ENSMUST00000028656.2
Duoxa2
dual oxidase maturation factor 2
chr9_+_44410417 0.25 ENSMUST00000074989.7
ENSMUST00000218913.2
Bcl9l
B cell CLL/lymphoma 9-like
chr11_-_21321144 0.23 ENSMUST00000060895.6
Ugp2
UDP-glucose pyrophosphorylase 2
chr1_-_136877277 0.22 ENSMUST00000168126.7
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chr1_-_136876902 0.19 ENSMUST00000195428.2
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chr7_+_114344920 0.19 ENSMUST00000136645.8
ENSMUST00000169913.8
Insc
INSC spindle orientation adaptor protein
chr7_-_105436775 0.18 ENSMUST00000078482.13
Dchs1
dachsous cadherin related 1
chr17_-_13087012 0.18 ENSMUST00000089015.10
Mas1
MAS1 oncogene
chrX_+_98086187 0.18 ENSMUST00000036606.14
Stard8
START domain containing 8
chr11_-_51748450 0.17 ENSMUST00000020655.14
ENSMUST00000109090.8
Jade2
jade family PHD finger 2
chr2_-_122128930 0.13 ENSMUST00000237546.2
Duox2
dual oxidase 2
chr11_+_98239230 0.12 ENSMUST00000078694.13
Ppp1r1b
protein phosphatase 1, regulatory inhibitor subunit 1B
chr11_-_23720953 0.11 ENSMUST00000102864.5
Rel
reticuloendotheliosis oncogene
chr8_-_129791969 0.08 ENSMUST00000125112.8
ENSMUST00000108747.3
ENSMUST00000214889.2
ENSMUST00000095158.11
Ccdc7a
coiled-coil domain containing 7A
chr9_-_72946928 0.08 ENSMUST00000184389.8
Pigb
phosphatidylinositol glycan anchor biosynthesis, class B
chr8_+_129793610 0.06 ENSMUST00000108745.8
Ccdc7b
coiled-coil domain containing 7B
chr8_+_129793635 0.06 ENSMUST00000026912.8
Ccdc7b
coiled-coil domain containing 7B
chr10_+_75160692 0.06 ENSMUST00000217703.2
Adora2a
adenosine A2a receptor
chr7_-_104577264 0.06 ENSMUST00000215359.2
Olfr668
olfactory receptor 668
chr2_+_54326329 0.05 ENSMUST00000112636.8
ENSMUST00000112635.8
ENSMUST00000112634.8
Galnt13
polypeptide N-acetylgalactosaminyltransferase 13
chr4_+_152200770 0.04 ENSMUST00000035275.8
Tnfrsf25
tumor necrosis factor receptor superfamily, member 25
chr17_-_29456750 0.04 ENSMUST00000137727.3
Cpne5
copine V
chr19_+_5497575 0.02 ENSMUST00000025850.7
ENSMUST00000236774.2
Fosl1
fos-like antigen 1
chr1_+_24216691 0.01 ENSMUST00000054588.15
Col9a1
collagen, type IX, alpha 1
chr12_+_51395154 0.01 ENSMUST00000121521.2
G2e3
G2/M-phase specific E3 ubiquitin ligase
chrY_+_7722941 0.01 ENSMUST00000189007.2
Gm28576
predicted gene 28576
chrY_+_7253787 0.01 ENSMUST00000186194.2
Gm28998
predicted gene 28998
chr6_+_15196950 0.01 ENSMUST00000140557.8
ENSMUST00000131414.8
ENSMUST00000115469.8
Foxp2
forkhead box P2
chr9_+_35580941 0.00 ENSMUST00000217565.2
Pate2
prostate and testis expressed 2
chr7_-_45750050 0.00 ENSMUST00000209291.2
Kcnj11
potassium inwardly rectifying channel, subfamily J, member 11

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0090274 reduction of food intake in response to dietary excess(GO:0002023) positive regulation of somatostatin secretion(GO:0090274)
0.1 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.3 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 10.0 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation