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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Tbx4

Z-value: 1.29

Motif logo

Transcription factors associated with Tbx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000000094.13 Tbx4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx4mm39_v1_chr11_+_85780807_85780889-0.473.8e-03Click!

Activity profile of Tbx4 motif

Sorted Z-values of Tbx4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_+_20579322 11.63 ENSMUST00000087638.4
aldehyde dehydrogenase family 1, subfamily A1
chr10_+_87697155 5.70 ENSMUST00000122100.3
insulin-like growth factor 1
chr17_-_34218301 5.03 ENSMUST00000235463.2
histocompatibility 2, K1, K region
chr19_+_37686240 4.82 ENSMUST00000025946.7
cytochrome P450, family 26, subfamily a, polypeptide 1
chr7_-_100307601 3.54 ENSMUST00000138830.2
ENSMUST00000107044.10
ENSMUST00000116287.9
pleckstrin homology domain containing, family B (evectins) member 1
chr10_-_86541349 2.90 ENSMUST00000020238.14
heat shock protein 90, beta (Grp94), member 1
chr16_-_23807602 2.77 ENSMUST00000023151.6
B cell leukemia/lymphoma 6
chr7_-_100307571 2.49 ENSMUST00000107043.8
pleckstrin homology domain containing, family B (evectins) member 1
chr4_+_43641262 2.19 ENSMUST00000123351.8
ENSMUST00000128549.3
natriuretic peptide receptor 2
chr9_-_43151179 1.98 ENSMUST00000034512.7
out at first homolog
chr19_-_42190589 1.86 ENSMUST00000018966.8
secreted frizzled-related sequence protein 5
chr15_+_57558048 1.71 ENSMUST00000096430.11
zinc fingers and homeoboxes 2
chr4_+_53440516 1.55 ENSMUST00000107651.9
ENSMUST00000107647.8
solute carrier family 44, member 1
chr7_+_46445512 1.53 ENSMUST00000006774.11
ENSMUST00000165031.8
general transcription factor II H, polypeptide 1
chr9_+_102885156 1.52 ENSMUST00000035148.13
solute carrier organic anion transporter family, member 2a1
chr3_-_75464066 1.41 ENSMUST00000162138.2
ENSMUST00000029424.12
ENSMUST00000161137.8
programmed cell death 10
chr11_+_95304903 1.29 ENSMUST00000107724.9
ENSMUST00000150884.8
ENSMUST00000107722.8
ENSMUST00000127713.2
speckle-type BTB/POZ protein
chr7_-_28001624 1.25 ENSMUST00000108315.4
delta like canonical Notch ligand 3
chr14_+_45588509 1.21 ENSMUST00000226873.2
serine/threonine/tyrosine interaction protein
chr2_+_164404499 1.13 ENSMUST00000017867.10
ENSMUST00000109344.9
ENSMUST00000109345.9
WAP four-disulfide core domain 2
chr11_+_78068931 1.10 ENSMUST00000147819.8
TLC domain containing 1
chr2_-_147887810 1.09 ENSMUST00000109964.8
forkhead box A2
chr3_+_40905066 1.07 ENSMUST00000191805.7
La ribonucleoprotein domain family, member 1B
chr1_-_105284383 1.04 ENSMUST00000058688.7
ring finger protein 152
chr13_+_96679110 1.04 ENSMUST00000179226.8
ceramide transporter 1
chrX_+_100427331 1.02 ENSMUST00000119190.2
gap junction protein, beta 1
chr13_-_111626562 1.01 ENSMUST00000091236.11
ENSMUST00000047627.14
GC-rich promoter binding protein 1
chr13_+_96679233 0.99 ENSMUST00000077672.12
ENSMUST00000109444.3
ceramide transporter 1
chr7_-_28078671 0.98 ENSMUST00000209061.2
zinc finger protein 36
chr10_+_86541675 0.96 ENSMUST00000075632.14
ENSMUST00000217747.2
ENSMUST00000061458.9
tetratricopeptide repeat domain 41
chr15_-_81244940 0.95 ENSMUST00000023040.9
solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
chr15_-_76004395 0.94 ENSMUST00000239552.1
epiplakin 1
chr14_-_55762395 0.94 ENSMUST00000228287.2
neural retina leucine zipper gene
chr14_-_55762416 0.92 ENSMUST00000178694.3
neural retina leucine zipper gene
chr6_+_42263644 0.92 ENSMUST00000163936.8
chloride channel, voltage-sensitive 1
chr3_+_40905216 0.92 ENSMUST00000191872.6
ENSMUST00000200432.2
La ribonucleoprotein domain family, member 1B
chr1_-_57010921 0.92 ENSMUST00000114415.10
special AT-rich sequence binding protein 2
chr3_+_75464837 0.91 ENSMUST00000161776.8
ENSMUST00000029423.9
serine (or cysteine) peptidase inhibitor, clade I, member 1
chr13_-_96678987 0.91 ENSMUST00000022172.12
polymerase (DNA directed), kappa
chr18_-_46345661 0.90 ENSMUST00000037011.6
tripartite motif-containing 36
chr14_-_55762432 0.89 ENSMUST00000062232.15
neural retina leucine zipper gene
chr17_-_79244460 0.88 ENSMUST00000024885.10
CCAAT/enhancer binding protein zeta
chr6_+_42263609 0.88 ENSMUST00000238845.2
ENSMUST00000031894.13
chloride channel, voltage-sensitive 1
chr1_-_105284407 0.87 ENSMUST00000172299.2
ring finger protein 152
chrM_+_9459 0.83 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr11_-_23720953 0.83 ENSMUST00000102864.5
reticuloendotheliosis oncogene
chr2_+_28403084 0.81 ENSMUST00000135803.8
ral guanine nucleotide dissociation stimulator
chr1_-_132953068 0.80 ENSMUST00000186617.7
ENSMUST00000067429.10
ENSMUST00000067398.13
ENSMUST00000188090.7
transformed mouse 3T3 cell double minute 4
chrX_+_167819606 0.80 ENSMUST00000087016.11
ENSMUST00000112129.8
ENSMUST00000112131.9
Rho GTPase activating protein 6
chr18_+_36414122 0.77 ENSMUST00000051301.6
purine rich element binding protein A
chr6_-_28261881 0.77 ENSMUST00000115320.8
ENSMUST00000123098.8
ENSMUST00000115321.9
ENSMUST00000155494.2
zinc finger protein 800
chr11_-_98040377 0.76 ENSMUST00000103143.10
F-box and leucine-rich repeat protein 20
chr5_+_120651158 0.74 ENSMUST00000111889.2
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr14_+_45588632 0.73 ENSMUST00000228818.2
serine/threonine/tyrosine interaction protein
chr19_+_21249636 0.72 ENSMUST00000237651.2
zinc finger, AN1-type domain 5
chr2_+_32498997 0.71 ENSMUST00000143625.2
ENSMUST00000128811.2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr16_+_84631956 0.71 ENSMUST00000009120.8
GA repeat binding protein, alpha
chr4_-_63779562 0.71 ENSMUST00000030047.3
tumor necrosis factor (ligand) superfamily, member 8
chr16_-_9812410 0.71 ENSMUST00000115835.8
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
chr13_-_96678844 0.69 ENSMUST00000223475.2
polymerase (DNA directed), kappa
chr11_-_106192627 0.68 ENSMUST00000103071.4
growth hormone
chrM_+_10167 0.67 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr11_-_86435579 0.66 ENSMUST00000138810.3
ENSMUST00000058286.9
ENSMUST00000154617.8
ribosomal protein S6 kinase, polypeptide 1
chr2_+_103254465 0.66 ENSMUST00000171693.8
E74-like factor 5
chr14_-_30665232 0.65 ENSMUST00000006704.17
ENSMUST00000163118.2
inter-alpha trypsin inhibitor, heavy chain 1
chr2_+_136733421 0.65 ENSMUST00000141463.8
SLX4 interacting protein
chr13_+_93440572 0.65 ENSMUST00000109493.9
homer scaffolding protein 1
chr3_-_121056944 0.65 ENSMUST00000128909.8
ENSMUST00000029777.14
TLC domain containing 4
chr6_+_7555053 0.64 ENSMUST00000090679.9
ENSMUST00000184986.2
tachykinin 1
chr2_+_103254401 0.63 ENSMUST00000028609.14
E74-like factor 5
chr16_+_84631789 0.62 ENSMUST00000114184.8
GA repeat binding protein, alpha
chr9_+_108174052 0.62 ENSMUST00000035230.7
aminomethyltransferase
chr4_-_19922599 0.61 ENSMUST00000029900.6
ATPase, H+ transporting, lysosomal V0 subunit D2
chr7_-_119694400 0.60 ENSMUST00000209154.3
ENSMUST00000046993.4
dynein, axonemal, heavy chain 3
chr15_+_38219447 0.59 ENSMUST00000081966.5
outer dense fiber of sperm tails 1
chr4_+_156214969 0.58 ENSMUST00000209248.2
ring finger 223
chr11_-_51748450 0.58 ENSMUST00000020655.14
ENSMUST00000109090.8
jade family PHD finger 2
chr5_-_24556602 0.57 ENSMUST00000036092.10
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr6_-_28831746 0.57 ENSMUST00000062304.7
leucine rich repeat containing 4
chr16_+_62635039 0.57 ENSMUST00000055557.6
syntaxin 19
chr12_+_88920169 0.56 ENSMUST00000057634.14
neurexin III
chr5_+_17779721 0.56 ENSMUST00000169603.2
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chrM_+_9870 0.55 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr8_-_32499513 0.55 ENSMUST00000208205.3
neuregulin 1
chr2_-_103627937 0.55 ENSMUST00000028607.13
cell cycle associated protein 1
chr14_+_54014387 0.54 ENSMUST00000103670.4
T cell receptor alpha variable 3-4
chr6_-_139987135 0.54 ENSMUST00000032356.13
phospholipase C, zeta 1
chr7_+_45890379 0.53 ENSMUST00000164538.2
otogelin
chr7_-_73663422 0.51 ENSMUST00000026896.10
ENSMUST00000191970.2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr4_-_42168603 0.49 ENSMUST00000098121.4
predicted gene 13305
chr4_-_42665763 0.49 ENSMUST00000238770.2
interleukin 11 receptor, alpha chain 2
chr18_+_69654572 0.48 ENSMUST00000200862.4
transcription factor 4
chr9_+_32283779 0.47 ENSMUST00000047334.10
potassium inwardly-rectifying channel, subfamily J, member 1
chr1_+_59563453 0.46 ENSMUST00000186434.3
predicted gene 973
chr12_+_102915102 0.46 ENSMUST00000101099.12
unc-79 homolog
chr11_-_22236795 0.45 ENSMUST00000180360.8
ENSMUST00000109563.9
EH domain binding protein 1
chr13_+_113346193 0.45 ENSMUST00000038144.9
endothelial cell-specific molecule 1
chr7_+_79460475 0.45 ENSMUST00000107394.3
mesoderm posterior 2
chr14_+_52131067 0.44 ENSMUST00000047726.12
solute carrier family 39 (zinc transporter), member 2
chr12_+_102915709 0.44 ENSMUST00000179002.8
unc-79 homolog
chr4_+_148085179 0.43 ENSMUST00000103230.5
natriuretic peptide type A
chr16_-_9812787 0.42 ENSMUST00000199708.5
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
chrX_+_41239872 0.42 ENSMUST00000123245.8
stromal antigen 2
chr7_-_46445085 0.42 ENSMUST00000123725.2
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
chrX_-_161612373 0.42 ENSMUST00000041370.11
ENSMUST00000112316.9
ENSMUST00000112315.2
taxilin gamma
chr5_+_115568638 0.42 ENSMUST00000131079.8
musashi RNA-binding protein 1
chr1_+_153541020 0.41 ENSMUST00000152114.8
ENSMUST00000111812.8
regulator of G-protein signaling 8
chr12_+_88689638 0.40 ENSMUST00000190626.7
ENSMUST00000167103.8
neurexin III
chr15_+_10952418 0.40 ENSMUST00000022853.15
ENSMUST00000110523.2
C1q and tumor necrosis factor related protein 3
chr2_+_54326443 0.39 ENSMUST00000136642.2
polypeptide N-acetylgalactosaminyltransferase 13
chr1_-_3741721 0.39 ENSMUST00000070533.5
X-linked Kx blood group related 4
chr14_-_70879694 0.39 ENSMUST00000227123.2
ENSMUST00000022697.7
fibroblast growth factor 17
chr7_+_4240697 0.38 ENSMUST00000117550.2
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr18_+_69654992 0.36 ENSMUST00000201627.4
transcription factor 4
chr2_+_54326329 0.35 ENSMUST00000112636.8
ENSMUST00000112635.8
ENSMUST00000112634.8
polypeptide N-acetylgalactosaminyltransferase 13
chr11_+_23256883 0.35 ENSMUST00000180046.8
ubiquitin specific peptidase 34
chr6_-_126143710 0.34 ENSMUST00000050484.9
neurotrophin 3
chr13_-_108295018 0.34 ENSMUST00000225830.2
ENSMUST00000223734.2
ENSMUST00000163558.3
NADH:ubiquinone oxidoreductase complex assembly factor 2
chr6_-_24956296 0.34 ENSMUST00000127247.4
transmembrane protein 229A
chr19_-_28941264 0.34 ENSMUST00000161813.2
spermatogenesis associated 6 like
chr18_+_69654900 0.33 ENSMUST00000202057.4
transcription factor 4
chr4_-_72770859 0.33 ENSMUST00000179234.2
ENSMUST00000078617.5
aldolase 1 A, retrogene 1
chr9_+_32027335 0.33 ENSMUST00000174641.8
Rho GTPase activating protein 32
chr7_-_108529375 0.33 ENSMUST00000055745.5
NLR family, pyrin domain containing 10
chrX_+_99773784 0.32 ENSMUST00000113744.2
glycerophosphodiester phosphodiesterase domain containing 2
chr2_+_52747855 0.32 ENSMUST00000155586.9
ENSMUST00000090952.11
ENSMUST00000127122.9
ENSMUST00000049483.14
ENSMUST00000050719.13
formin-like 2
chrX_-_156826262 0.32 ENSMUST00000026750.15
ENSMUST00000112513.2
connector enhancer of kinase suppressor of Ras 2
chr11_-_99511257 0.32 ENSMUST00000073853.3
predicted gene 11562
chr9_-_58109627 0.31 ENSMUST00000216231.2
immunoglobulin superfamily containing leucine-rich repeat 2
chr3_+_55369384 0.31 ENSMUST00000200352.2
doublecortin-like kinase 1
chr3_-_30194559 0.30 ENSMUST00000108271.10
MDS1 and EVI1 complex locus
chr2_+_164810139 0.30 ENSMUST00000202479.4
solute carrier family 12, member 5
chr4_+_117706559 0.30 ENSMUST00000163288.2
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr10_+_97528915 0.29 ENSMUST00000060703.6
coiled-coil glutamate-rich protein 1
chr12_-_31684588 0.28 ENSMUST00000020979.9
ENSMUST00000177962.9
B cell receptor associated protein 29
chr3_+_55369149 0.28 ENSMUST00000199585.5
ENSMUST00000070418.9
doublecortin-like kinase 1
chr19_-_37184692 0.28 ENSMUST00000132580.8
ENSMUST00000079754.11
ENSMUST00000136286.8
ENSMUST00000126188.8
ENSMUST00000126781.2
cytoplasmic polyadenylation element binding protein 3
chr4_+_125384481 0.28 ENSMUST00000030676.8
glutamate receptor, ionotropic, kainate 3
chr13_+_81034214 0.28 ENSMUST00000161441.2
arrestin domain containing 3
chr8_-_32499556 0.28 ENSMUST00000207470.3
ENSMUST00000207417.3
ENSMUST00000238826.2
neuregulin 1
chr4_+_42950367 0.27 ENSMUST00000084662.12
DnaJ heat shock protein family (Hsp40) member B5
chr3_-_94490023 0.27 ENSMUST00000029783.16
sorting nexin family member 27
chr6_-_94677118 0.27 ENSMUST00000101126.3
ENSMUST00000032105.11
leucine-rich repeats and immunoglobulin-like domains 1
chr12_-_11258973 0.26 ENSMUST00000049877.3
mesogenin 1
chr7_-_79443536 0.26 ENSMUST00000032760.6
mesoderm posterior 1
chr5_+_115568002 0.26 ENSMUST00000067168.9
musashi RNA-binding protein 1
chr14_+_53574579 0.26 ENSMUST00000179580.3
T cell receptor alpha variable 13N-3
chrX_+_99773523 0.25 ENSMUST00000019503.14
glycerophosphodiester phosphodiesterase domain containing 2
chr2_+_130038463 0.24 ENSMUST00000166774.3
transmembrane channel-like gene family 2
chr1_-_161615927 0.24 ENSMUST00000193648.2
Fas ligand (TNF superfamily, member 6)
chr4_+_11191354 0.23 ENSMUST00000170901.8
cyclin E2
chr13_-_89890609 0.23 ENSMUST00000109546.9
versican
chrX_-_58613428 0.23 ENSMUST00000119833.8
ENSMUST00000131319.8
fibroblast growth factor 13
chr15_-_100583044 0.23 ENSMUST00000230312.2
chymotrypsin-like elastase family, member 1
chr1_+_6800275 0.23 ENSMUST00000043578.13
ENSMUST00000139756.8
ENSMUST00000131467.8
ENSMUST00000150761.8
ENSMUST00000151281.8
suppression of tumorigenicity 18
chr3_+_126391046 0.23 ENSMUST00000106401.8
calcium/calmodulin-dependent protein kinase II, delta
chr1_+_153541339 0.20 ENSMUST00000147700.8
ENSMUST00000147482.8
regulator of G-protein signaling 8
chr11_+_23256909 0.20 ENSMUST00000137823.8
ubiquitin specific peptidase 34
chr3_+_55369288 0.19 ENSMUST00000198412.5
ENSMUST00000199169.5
ENSMUST00000199702.5
ENSMUST00000198437.5
doublecortin-like kinase 1
chr11_-_94398162 0.19 ENSMUST00000040692.9
MYCBP associated protein
chr9_-_69668204 0.18 ENSMUST00000071281.5
forkhead box B1
chr1_+_74582044 0.18 ENSMUST00000113749.8
ENSMUST00000067916.13
ENSMUST00000113747.8
ENSMUST00000113750.8
phospholipase C, delta 4
chr19_-_32080496 0.18 ENSMUST00000235213.2
ENSMUST00000236504.2
N-acylsphingosine amidohydrolase 2
chr1_+_153541412 0.17 ENSMUST00000111814.8
ENSMUST00000111810.2
regulator of G-protein signaling 8
chr17_+_35878332 0.16 ENSMUST00000044326.5
RIKEN cDNA 2300002M23 gene
chr9_-_40915895 0.16 ENSMUST00000180384.3
cytotoxic and regulatory T cell molecule
chr7_-_46445305 0.15 ENSMUST00000107653.8
ENSMUST00000107654.8
ENSMUST00000014562.14
ENSMUST00000152759.8
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
chr8_-_32408864 0.15 ENSMUST00000073884.7
ENSMUST00000238812.2
neuregulin 1
chr1_-_126758520 0.15 ENSMUST00000162646.8
NCK-associated protein 5
chr6_+_72281587 0.15 ENSMUST00000183018.8
ENSMUST00000182014.10
surfactant associated protein B
chr2_-_91013193 0.14 ENSMUST00000111370.9
ENSMUST00000111376.8
ENSMUST00000099723.9
MAP-kinase activating death domain
chr1_+_40619215 0.14 ENSMUST00000027233.9
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr3_-_158267771 0.13 ENSMUST00000199890.5
ENSMUST00000238317.3
ENSMUST00000200137.5
ENSMUST00000106044.6
leucine rich repeat containing 7
chr16_-_32630847 0.13 ENSMUST00000179384.3
somatomedin B domain containing 1
chr2_-_13016570 0.13 ENSMUST00000061545.7
C1q-like 3
chr16_+_23807232 0.13 ENSMUST00000210705.2
predicted gene, 37419
chr12_-_56392646 0.13 ENSMUST00000021416.9
MAP3K12 binding inhibitory protein 1
chr18_-_65527078 0.13 ENSMUST00000035548.16
alpha-kinase 2
chr2_-_57004933 0.12 ENSMUST00000028166.9
nuclear receptor subfamily 4, group A, member 2
chr4_+_53440389 0.12 ENSMUST00000107646.9
ENSMUST00000102911.10
solute carrier family 44, member 1
chr9_-_102231884 0.12 ENSMUST00000035129.14
ENSMUST00000085169.12
ENSMUST00000149800.3
Eph receptor B1
chr2_-_91013362 0.12 ENSMUST00000066420.12
MAP-kinase activating death domain
chr1_+_66507523 0.11 ENSMUST00000061620.17
ENSMUST00000212557.3
unc-80, NALCN activator
chrX_+_41591410 0.11 ENSMUST00000005839.11
SH2 domain containing 1A
chr19_+_5742880 0.11 ENSMUST00000235661.2
mitogen-activated protein kinase kinase kinase 11
chr9_+_106247943 0.11 ENSMUST00000173748.2
dual specificity phosphatase 7
chr9_-_15834052 0.11 ENSMUST00000217187.2
FAT atypical cadherin 3
chr16_-_50151350 0.10 ENSMUST00000114488.8
bobby sox HMG box containing
chr9_-_40915858 0.09 ENSMUST00000188848.8
ENSMUST00000034519.13
cytotoxic and regulatory T cell molecule
chr8_-_32408380 0.09 ENSMUST00000208497.3
ENSMUST00000207584.3
neuregulin 1
chrX_+_41591476 0.08 ENSMUST00000115070.8
ENSMUST00000153948.2
SH2 domain containing 1A
chr19_+_23881821 0.07 ENSMUST00000237688.2
amyloid beta (A4) precursor protein binding, family A, member 1
chr2_+_106525938 0.07 ENSMUST00000016530.14
metallophosphoesterase domain containing 2
chr6_-_145811028 0.06 ENSMUST00000111703.2
basic helix-loop-helix family, member e41
chr16_-_32617783 0.06 ENSMUST00000115116.8
ENSMUST00000041123.9
mucin 20
chr4_+_119397710 0.06 ENSMUST00000160219.2
forkhead box J3
chrX_+_41591355 0.06 ENSMUST00000189753.7
SH2 domain containing 1A
chr19_+_28941292 0.05 ENSMUST00000045674.4
phospholipid phosphatase 6
chr18_+_32948436 0.04 ENSMUST00000025237.5
thymic stromal lymphopoietin
chr9_-_99592058 0.01 ENSMUST00000136429.8
claudin 18

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 10.8 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.0 5.0 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.8 5.7 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.7 2.8 GO:0043380 regulation of memory T cell differentiation(GO:0043380)
0.7 4.8 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.6 1.9 GO:0045204 MAPK export from nucleus(GO:0045204)
0.6 1.9 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.6 2.8 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.5 1.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.3 1.0 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.3 1.0 GO:1904582 positive regulation of intracellular mRNA localization(GO:1904582)
0.3 2.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 1.2 GO:0007386 compartment pattern specification(GO:0007386)
0.2 1.7 GO:0015871 choline transport(GO:0015871)
0.2 1.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.2 0.6 GO:0035934 corticosterone secretion(GO:0035934)
0.2 0.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 1.3 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.2 2.9 GO:0071318 cellular response to ATP(GO:0071318)
0.2 2.0 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.2 1.6 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 1.1 GO:0033058 directional locomotion(GO:0033058)
0.1 1.8 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.3 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.6 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 0.3 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.1 1.1 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 1.9 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.4 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.3 GO:0040040 thermosensory behavior(GO:0040040)
0.1 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.3 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.7 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 1.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.3 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.1 0.8 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.1 0.3 GO:0002355 detection of tumor cell(GO:0002355)
0.1 1.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.6 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 1.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.9 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 1.5 GO:0015732 prostaglandin transport(GO:0015732)
0.1 0.4 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.1 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.6 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.3 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 1.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0007403 glial cell fate determination(GO:0007403)
0.0 0.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.5 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.8 GO:0003283 atrial septum development(GO:0003283)
0.0 0.8 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 1.0 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:0060309 elastin catabolic process(GO:0060309)
0.0 0.7 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.5 GO:0007343 egg activation(GO:0007343)
0.0 0.2 GO:0007412 axon target recognition(GO:0007412) hypothalamus cell migration(GO:0021855) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.6 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 1.1 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.6 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.7 GO:0003016 respiratory system process(GO:0003016)
0.0 0.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 1.2 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.8 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.1 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.7 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.8 GO:0001662 behavioral fear response(GO:0001662)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.4 5.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 0.9 GO:0060205 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.2 2.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 1.5 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.0 GO:0070578 RISC-loading complex(GO:0070578)
0.1 2.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.8 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.6 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.6 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 2.8 GO:0005657 replication fork(GO:0005657)
0.0 0.7 GO:0030061 mitochondrial crista(GO:0030061)
0.0 4.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.1 GO:0030673 axolemma(GO:0030673)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.7 GO:0070469 respiratory chain(GO:0070469)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.6 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.8 4.8 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 1.9 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 5.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.3 1.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.3 1.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 2.9 GO:0046790 virion binding(GO:0046790)
0.2 0.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.0 GO:0051185 coenzyme transporter activity(GO:0051185)
0.2 0.7 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.2 2.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 2.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.4 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.7 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 5.7 GO:0043539 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.5 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 1.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.3 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.1 1.0 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.6 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 1.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0070052 collagen V binding(GO:0070052)
0.0 1.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 1.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 6.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.6 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 PID IGF1 PATHWAY IGF1 pathway
0.0 3.5 PID FOXO PATHWAY FoxO family signaling
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 2.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.2 PID IFNG PATHWAY IFN-gamma pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 11.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 2.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 4.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.0 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells