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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Tbx5

Z-value: 2.01

Motif logo

Transcription factors associated with Tbx5

Gene Symbol Gene ID Gene Info
ENSMUSG00000018263.12 Tbx5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx5mm39_v1_chr5_+_119970733_1199707800.095.9e-01Click!

Activity profile of Tbx5 motif

Sorted Z-values of Tbx5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_-_106660470 15.12 ENSMUST00000034368.8
chymotrypsin-like
chr3_-_20329823 12.20 ENSMUST00000011607.6
carboxypeptidase B1 (tissue)
chr6_+_30639217 11.85 ENSMUST00000031806.10
carboxypeptidase A1, pancreatic
chr7_-_126651847 7.65 ENSMUST00000205424.2
zymogen granule protein 16
chr15_-_100583044 7.28 ENSMUST00000230312.2
chymotrypsin-like elastase family, member 1
chr14_+_80237691 7.17 ENSMUST00000228749.2
ENSMUST00000088735.4
olfactomedin 4
chr3_-_100396635 7.06 ENSMUST00000061455.9
terminal nucleotidyltransferase 5C
chr10_+_43455919 6.78 ENSMUST00000214476.2
CD24a antigen
chr1_-_132318039 6.74 ENSMUST00000132435.2
transmembrane and coiled-coil domains 2
chr15_-_103163860 6.55 ENSMUST00000075192.13
nuclear factor, erythroid derived 2
chr14_-_70855980 6.36 ENSMUST00000228001.2
dematin actin binding protein
chr7_-_142220553 6.32 ENSMUST00000105935.8
insulin-like growth factor 2
chr10_+_75402090 6.08 ENSMUST00000129232.8
ENSMUST00000143792.8
gamma-glutamyltransferase 1
chr8_+_23525101 5.74 ENSMUST00000117662.8
ENSMUST00000117296.8
ENSMUST00000141784.9
ankyrin 1, erythroid
chr2_-_32277773 5.10 ENSMUST00000050785.14
lipocalin 2
chr2_+_103800553 5.04 ENSMUST00000111140.3
ENSMUST00000111139.3
LIM domain only 2
chr15_+_73620213 4.99 ENSMUST00000053232.8
protein tyrosine phosphatase 4a3
chr2_+_103800459 4.81 ENSMUST00000111143.8
ENSMUST00000138815.2
LIM domain only 2
chr11_+_70529944 4.76 ENSMUST00000055184.7
ENSMUST00000108551.3
glycoprotein 1b, alpha polypeptide
chr7_-_44888220 4.56 ENSMUST00000210372.2
ENSMUST00000209779.2
ENSMUST00000098461.10
ENSMUST00000211373.2
CD37 antigen
chr2_-_32278245 4.56 ENSMUST00000192241.2
lipocalin 2
chr5_-_148336711 4.54 ENSMUST00000048116.15
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr9_-_95727267 4.51 ENSMUST00000093800.9
plastin 1 (I-isoform)
chr15_-_89310060 4.38 ENSMUST00000109313.9
carnitine palmitoyltransferase 1b, muscle
chr11_+_53410552 4.00 ENSMUST00000108987.8
ENSMUST00000121334.8
ENSMUST00000117061.8
septin 8
chr4_+_114916703 3.86 ENSMUST00000162489.2
T cell acute lymphocytic leukemia 1
chr7_-_44888532 3.85 ENSMUST00000033063.15
CD37 antigen
chr7_+_28682253 3.85 ENSMUST00000085835.8
mitogen-activated protein kinase kinase kinase kinase 1
chr11_-_87766350 3.77 ENSMUST00000049768.4
eosinophil peroxidase
chr14_-_56322654 3.71 ENSMUST00000015594.9
mast cell protease 8
chr15_-_82917495 3.53 ENSMUST00000231165.2
Nfat activating molecule with ITAM motif 1
chrX_-_36253309 3.52 ENSMUST00000060474.14
ENSMUST00000053456.11
ENSMUST00000115239.10
septin 6
chr10_+_60182630 3.45 ENSMUST00000020301.14
ENSMUST00000105460.8
ENSMUST00000170507.8
V-set immunoregulatory receptor
chr2_-_181333597 3.43 ENSMUST00000108778.8
ENSMUST00000165416.8
regulator of G-protein signaling 19
chr7_+_81508741 3.32 ENSMUST00000041890.8
transmembrane 6 superfamily member 1
chr6_-_49191891 3.30 ENSMUST00000031838.9
insulin-like growth factor 2 mRNA binding protein 3
chr17_+_47816137 3.18 ENSMUST00000182935.8
ENSMUST00000182506.8
cyclin D3
chr17_+_47816074 3.17 ENSMUST00000183177.8
ENSMUST00000182848.8
cyclin D3
chr3_+_108291145 3.14 ENSMUST00000090561.10
ENSMUST00000102629.8
ENSMUST00000128089.2
proline/serine-rich coiled-coil 1
chr17_+_47815968 3.14 ENSMUST00000182129.8
ENSMUST00000171031.8
cyclin D3
chr17_-_28736483 2.99 ENSMUST00000114792.8
ENSMUST00000177939.8
FK506 binding protein 5
chr11_+_68986043 2.96 ENSMUST00000101004.9
period circadian clock 1
chr17_+_47908025 2.92 ENSMUST00000183206.2
cyclin D3
chr11_-_46203047 2.91 ENSMUST00000129474.2
ENSMUST00000093166.11
ENSMUST00000165599.9
cytoplasmic FMR1 interacting protein 2
chr19_+_3372296 2.85 ENSMUST00000237938.2
carnitine palmitoyltransferase 1a, liver
chr11_+_115044966 2.82 ENSMUST00000021076.6
RAB37, member RAS oncogene family
chr6_+_35229628 2.81 ENSMUST00000130875.8
RIKEN cDNA 1810058I24 gene
chr15_+_79578141 2.79 ENSMUST00000230898.2
ENSMUST00000229046.2
GTP binding protein 1
chr7_+_43086432 2.67 ENSMUST00000070518.4
natural killer cell group 7 sequence
chr7_-_44888465 2.66 ENSMUST00000210078.2
CD37 antigen
chrX_+_99669343 2.63 ENSMUST00000048962.4
kinesin family member 4
chr17_+_47816042 2.61 ENSMUST00000183044.8
ENSMUST00000037333.17
cyclin D3
chr7_+_140711181 2.57 ENSMUST00000026568.10
phosphatidylserine synthase 2
chr12_-_114252202 2.49 ENSMUST00000195124.6
ENSMUST00000103481.3
immunoglobulin heavy variable 3-6
chr5_-_22549688 2.47 ENSMUST00000062372.14
ENSMUST00000161356.8
reelin
chr11_+_78079243 2.44 ENSMUST00000002128.14
ENSMUST00000150941.8
RAB34, member RAS oncogene family
chr10_+_80692948 2.39 ENSMUST00000220091.2
signal peptide peptidase like 2B
chr6_+_35229589 2.34 ENSMUST00000152147.8
RIKEN cDNA 1810058I24 gene
chr9_+_72952115 2.33 ENSMUST00000184146.8
ENSMUST00000034722.5
RAB27A, member RAS oncogene family
chr6_+_4504814 2.31 ENSMUST00000141483.8
collagen, type I, alpha 2
chr15_-_82128538 2.30 ENSMUST00000229747.2
ENSMUST00000230408.2
centromere protein M
chr17_+_48571298 2.29 ENSMUST00000059873.14
ENSMUST00000154335.8
ENSMUST00000136272.8
ENSMUST00000125426.8
ENSMUST00000153420.2
triggering receptor expressed on myeloid cells-like 4
chr3_-_92493507 2.21 ENSMUST00000194965.6
sperm mitochondria-associated cysteine-rich protein
chr14_-_51295099 2.19 ENSMUST00000227764.2
ribonuclease, RNase A family, 12 (non-active)
chr19_-_10282218 2.18 ENSMUST00000039327.11
diacylglycerol lipase, alpha
chr7_+_43086554 2.17 ENSMUST00000206741.2
natural killer cell group 7 sequence
chr15_+_79231720 2.15 ENSMUST00000096350.11
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr3_+_90173813 2.15 ENSMUST00000098914.10
DENN/MADD domain containing 4B
chr9_+_37439367 2.11 ENSMUST00000002011.14
endothelial cell-specific adhesion molecule
chr11_-_100305654 2.03 ENSMUST00000066489.13
prolyl 3-hydroxylase family member 4 (non-enzymatic)
chr19_+_38085510 2.02 ENSMUST00000067098.8
free fatty acid receptor 4
chr4_-_43045685 1.99 ENSMUST00000107956.8
ENSMUST00000107957.8
family with sequence similarity 214, member B
chrX_-_48886577 1.97 ENSMUST00000033442.14
ENSMUST00000114891.2
immunoglobulin superfamily, member 1
chr12_-_113823290 1.92 ENSMUST00000103459.5
immunoglobulin heavy variable 5-17
chr11_+_69792642 1.92 ENSMUST00000177138.8
ENSMUST00000108617.10
ENSMUST00000177476.8
ENSMUST00000061837.11
neuralized E3 ubiquitin protein ligase 4
chr1_+_91294133 1.86 ENSMUST00000086861.12
erythroferrone
chr7_-_45044606 1.85 ENSMUST00000209858.2
small nuclear ribonucleoprotein 70 (U1)
chr15_+_79230777 1.81 ENSMUST00000229130.2
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr18_-_55123153 1.80 ENSMUST00000064763.7
zinc finger protein 608
chr1_+_39407183 1.79 ENSMUST00000195123.6
ribosomal protein L31
chr7_-_25488060 1.76 ENSMUST00000002677.11
ENSMUST00000085948.11
AXL receptor tyrosine kinase
chr7_-_141023902 1.76 ENSMUST00000026580.12
p53 induced death domain protein 1
chr9_-_106762818 1.69 ENSMUST00000185707.2
RNA binding motif protein 15B
chr4_+_132495636 1.68 ENSMUST00000102561.11
replication protein A2
chr4_-_117740624 1.64 ENSMUST00000030266.12
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr19_+_54033681 1.63 ENSMUST00000237285.2
adrenergic receptor, alpha 2a
chr11_+_78079562 1.62 ENSMUST00000108322.9
RAB34, member RAS oncogene family
chr7_+_89779564 1.62 ENSMUST00000208742.2
ENSMUST00000049537.9
phosphatidylinositol binding clathrin assembly protein
chr1_-_167112784 1.60 ENSMUST00000053686.9
uridine-cytidine kinase 2
chr6_-_40562700 1.58 ENSMUST00000177178.2
ENSMUST00000129948.9
ENSMUST00000101491.11
C-type lectin domain family 5, member a
chr7_+_24967094 1.57 ENSMUST00000169266.8
capicua transcriptional repressor
chr9_+_108820846 1.57 ENSMUST00000198140.5
ENSMUST00000051873.15
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr7_-_24771717 1.55 ENSMUST00000003468.10
glutamate receptor, ionotropic, kainate 5 (gamma 2)
chr10_+_122514669 1.46 ENSMUST00000161487.8
ENSMUST00000067918.12
protein phosphatase 1H (PP2C domain containing)
chr7_-_35096133 1.41 ENSMUST00000154597.2
ENSMUST00000032704.12
Fanconi anemia core complex associated protein 24
chr6_+_17307639 1.40 ENSMUST00000115453.2
caveolin 1, caveolae protein
chr8_-_85413707 1.39 ENSMUST00000238301.2
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr11_+_96820220 1.37 ENSMUST00000062172.6
proline rich 15-like
chr1_+_132405099 1.36 ENSMUST00000190825.7
ENSMUST00000190997.7
ENSMUST00000187505.7
ENSMUST00000027700.15
ENSMUST00000188575.7
retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit
chr15_-_77653979 1.35 ENSMUST00000229259.2
myosin, heavy polypeptide 9, non-muscle
chr14_-_70414236 1.34 ENSMUST00000153735.8
PDZ and LIM domain 2
chrX_+_168468186 1.32 ENSMUST00000112107.8
ENSMUST00000112104.8
midline 1
chr12_-_113700190 1.32 ENSMUST00000103452.3
ENSMUST00000192264.2
immunoglobulin heavy variable 5-9-1
chr12_-_113589576 1.31 ENSMUST00000103446.2
immunoglobulin heavy variable 5-6
chr2_-_44817173 1.31 ENSMUST00000130991.8
glycosyltransferase-like domain containing 1
chrX_+_158623460 1.30 ENSMUST00000112451.8
ENSMUST00000112453.9
SH3-domain kinase binding protein 1
chr16_+_31247562 1.30 ENSMUST00000115227.10
3-hydroxybutyrate dehydrogenase, type 1
chr4_-_132125510 1.29 ENSMUST00000136711.2
ENSMUST00000084249.11
phosphatase and actin regulator 4
chr12_-_111638722 1.27 ENSMUST00000001304.9
creatine kinase, brain
chr8_+_121264161 1.24 ENSMUST00000118136.2
genetic suppressor element 1, coiled-coil protein
chr11_+_50101717 1.23 ENSMUST00000147468.8
mannoside acetylglucosaminyltransferase 4, isoenzyme B
chr17_+_32255071 1.22 ENSMUST00000081339.13
ribosomal RNA processing 1B
chr9_-_62444318 1.20 ENSMUST00000048043.12
coronin, actin binding protein, 2B
chr4_-_149858694 1.20 ENSMUST00000105686.3
solute carrier family 25, member 33
chr9_+_69902697 1.19 ENSMUST00000165389.8
BCL2/adenovirus E1B interacting protein 2
chr14_+_30973407 1.17 ENSMUST00000022458.11
Brca1 associated protein 1
chr8_+_121262528 1.16 ENSMUST00000120493.8
genetic suppressor element 1, coiled-coil protein
chr4_+_154255187 1.15 ENSMUST00000030897.15
multiple EGF-like-domains 6
chr4_-_133746138 1.15 ENSMUST00000051674.3
lin-28 homolog A (C. elegans)
chr3_+_123240562 1.14 ENSMUST00000029603.10
protease, serine 12 neurotrypsin (motopsin)
chr9_-_122123475 1.13 ENSMUST00000042546.4
anoctamin 10
chr18_+_82932747 1.12 ENSMUST00000071233.7
zinc finger protein 516
chr19_-_4861536 1.12 ENSMUST00000179909.8
ENSMUST00000172000.3
ENSMUST00000180008.2
ENSMUST00000113793.4
ENSMUST00000006625.8
predicted gene 21992
RNA binding motif protein 14
chr4_-_116982804 1.12 ENSMUST00000183310.2
BTB (POZ) domain containing 19
chr11_+_83553400 1.10 ENSMUST00000019074.4
chemokine (C-C motif) ligand 4
chr5_-_18093739 1.09 ENSMUST00000169095.6
ENSMUST00000197574.2
CD36 molecule
chr9_-_122123409 1.07 ENSMUST00000214409.2
anoctamin 10
chr17_+_28910714 1.07 ENSMUST00000233250.2
mitogen-activated protein kinase 14
chr18_+_23885390 1.07 ENSMUST00000170802.8
ENSMUST00000155708.8
ENSMUST00000118826.9
microtubule-associated protein, RP/EB family, member 2
chr8_+_106245368 1.05 ENSMUST00000034363.7
hydroxysteroid 11-beta dehydrogenase 2
chr3_+_96537235 1.00 ENSMUST00000048915.11
ENSMUST00000196456.5
ENSMUST00000198027.5
RNA binding motif protein 8a
chr7_+_25380583 0.99 ENSMUST00000108403.4
B9 protein domain 2
chrX_+_133195974 0.99 ENSMUST00000037687.8
transmembrane protein 35A
chr7_+_35096470 0.99 ENSMUST00000079414.12
centrosomal protein 89
chr5_-_100867520 0.98 ENSMUST00000112908.2
ENSMUST00000045617.15
heparanase
chrX_-_73009933 0.97 ENSMUST00000114372.3
ENSMUST00000033761.13
host cell factor C1
chr3_+_96537484 0.94 ENSMUST00000200647.2
RNA binding motif protein 8a
chr19_+_38384428 0.93 ENSMUST00000054098.4
solute carrier family 35, member G1
chr9_-_122123427 0.92 ENSMUST00000216670.2
anoctamin 10
chr11_+_6339061 0.91 ENSMUST00000109787.8
zinc finger, MIZ-type containing 2
chr19_-_46315543 0.91 ENSMUST00000223917.2
ENSMUST00000224447.2
ENSMUST00000041391.5
ENSMUST00000096029.12
pleckstrin and Sec7 domain containing
chr7_+_92426772 0.90 ENSMUST00000208945.2
RAB30, member RAS oncogene family
chr15_-_99355623 0.88 ENSMUST00000023747.14
NCK-associated protein 5-like
chr6_-_70237939 0.88 ENSMUST00000103386.3
immunoglobulin kappa variable 6-23
chr11_-_3321307 0.88 ENSMUST00000101640.10
ENSMUST00000101642.10
LIM motif-containing protein kinase 2
chr4_+_132291369 0.88 ENSMUST00000070690.8
platelet-activating factor receptor
chr6_-_113320858 0.88 ENSMUST00000155543.2
ENSMUST00000032409.15
calcium/calmodulin-dependent protein kinase I
chr12_-_113666198 0.88 ENSMUST00000103450.4
immunoglobulin heavy variable 5-12
chr5_-_148336574 0.87 ENSMUST00000202457.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chrX_+_73356597 0.87 ENSMUST00000114160.2
family with sequence similarity 50, member A
chr9_+_86625694 0.85 ENSMUST00000179574.2
ENSMUST00000036426.13
protease, serine 35
chr4_+_154954042 0.83 ENSMUST00000079269.14
ENSMUST00000163732.8
ENSMUST00000080559.13
membrane metallo-endopeptidase-like 1
chr2_-_131987008 0.82 ENSMUST00000028815.15
solute carrier family 23 (nucleobase transporters), member 2
chr9_-_116004386 0.81 ENSMUST00000035014.8
transforming growth factor, beta receptor II
chr11_+_20597149 0.80 ENSMUST00000109585.2
SERTA domain containing 2
chr6_-_136638926 0.79 ENSMUST00000032336.7
phospholipase B domain containing 1
chr6_-_49240944 0.79 ENSMUST00000204189.3
ENSMUST00000031841.9
transformer 2 alpha
chr13_+_49835667 0.79 ENSMUST00000172254.3
isoleucine-tRNA synthetase
chr9_-_62888156 0.78 ENSMUST00000098651.6
ENSMUST00000214830.2
protein inhibitor of activated STAT 1
chr18_+_36926929 0.78 ENSMUST00000001419.10
zinc finger, matrin type 2
chr17_+_28910393 0.78 ENSMUST00000124886.9
ENSMUST00000114758.9
mitogen-activated protein kinase 14
chr19_-_41373526 0.77 ENSMUST00000059672.9
phosphoinositide-3-kinase adaptor protein 1
chr6_+_17307272 0.77 ENSMUST00000115454.2
caveolin 1, caveolae protein
chr10_-_90918566 0.76 ENSMUST00000162618.8
ENSMUST00000020157.13
ENSMUST00000160788.2
apoptotic peptidase activating factor 1
chr2_+_24076481 0.76 ENSMUST00000057567.3
interleukin 1 family, member 9
chr1_-_74640504 0.76 ENSMUST00000136078.2
ENSMUST00000132081.2
ENSMUST00000113721.8
ENSMUST00000027357.12
ring finger protein 25
chr19_-_10581622 0.76 ENSMUST00000037678.7
triokinase, FMN cyclase
chr6_+_113284098 0.76 ENSMUST00000113122.8
ENSMUST00000204198.3
ENSMUST00000113121.8
ENSMUST00000113119.8
ENSMUST00000113117.4
ENSMUST00000204626.3
ENSMUST00000203577.2
bromodomain and PHD finger containing, 1
chr3_-_95264467 0.76 ENSMUST00000107171.10
ENSMUST00000015841.12
ENSMUST00000107170.3
SET domain, bifurcated 1
chr16_+_93480061 0.76 ENSMUST00000039620.7
carbonyl reductase 3
chr11_+_77923172 0.74 ENSMUST00000122342.2
ENSMUST00000092881.4
dehydrogenase/reductase (SDR family) member 13
chrX_-_7606445 0.73 ENSMUST00000128289.8
coiled-coil domain containing 120
chr7_-_3669882 0.72 ENSMUST00000145034.3
transmembrane channel-like gene family 4
chr3_+_126390600 0.70 ENSMUST00000106402.8
ENSMUST00000106399.8
ENSMUST00000066466.13
ENSMUST00000163226.8
ENSMUST00000199300.5
calcium/calmodulin-dependent protein kinase II, delta
chr1_-_131172903 0.70 ENSMUST00000027688.15
ENSMUST00000112442.2
Ras association (RalGDS/AF-6) domain family member 5
chr3_-_126792056 0.70 ENSMUST00000044443.15
ankyrin 2, brain
chr3_-_90373165 0.69 ENSMUST00000029540.13
natriuretic peptide receptor 1
chr7_-_140697719 0.69 ENSMUST00000067836.9
anoctamin 9
chr10_-_23977810 0.67 ENSMUST00000170267.3
trace amine-associated receptor 8C
chr12_-_113733922 0.67 ENSMUST00000180013.3
immunoglobulin heavy variable 2-9-1
chr12_-_113790741 0.67 ENSMUST00000103457.3
ENSMUST00000192877.2
immunoglobulin heavy variable 5-15
chr2_-_121287174 0.66 ENSMUST00000110613.9
ENSMUST00000056312.10
serine incorporator 4
chr16_-_18107046 0.65 ENSMUST00000232424.2
ENSMUST00000009321.11
DGCR8, microprocessor complex subunit
chr7_+_125151432 0.65 ENSMUST00000206217.2
ENSMUST00000205985.2
interleukin 4 receptor, alpha
chr2_-_25136857 0.65 ENSMUST00000228627.3
NADPH dependent diflavin oxidoreductase 1
chrX_+_20230720 0.63 ENSMUST00000033372.13
ENSMUST00000115391.8
ENSMUST00000115387.8
retinitis pigmentosa 2 homolog
chr11_-_96834771 0.63 ENSMUST00000107629.2
ENSMUST00000018803.12
pyridoxine 5'-phosphate oxidase
chr2_-_126985226 0.63 ENSMUST00000110386.2
ENSMUST00000132773.2
inositol 1,4,5-triphosphate receptor interacting protein-like 1
chr2_-_91274967 0.63 ENSMUST00000064652.14
ENSMUST00000102594.11
ENSMUST00000094835.9
RIKEN cDNA 1110051M20 gene
chr8_+_55024446 0.63 ENSMUST00000239166.2
ENSMUST00000239106.2
ENSMUST00000239152.2
ankyrin repeat and SOCs box-containing 5
chr7_-_28297565 0.62 ENSMUST00000040531.9
ENSMUST00000108283.8
sterile alpha motif domain containing 4B
p21 (RAC1) activated kinase 4
chr11_-_70111796 0.62 ENSMUST00000060010.3
ENSMUST00000190533.2
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr10_+_56253418 0.62 ENSMUST00000068581.9
ENSMUST00000217789.2
gap junction protein, alpha 1
chr1_+_74448535 0.59 ENSMUST00000027366.13
villin 1
chr4_+_62398262 0.58 ENSMUST00000030088.12
ENSMUST00000107449.4
B-box and SPRY domain containing
chr3_-_95214102 0.57 ENSMUST00000107183.8
ENSMUST00000164406.8
ENSMUST00000123365.2
annexin A9
chr11_-_69791712 0.57 ENSMUST00000108621.9
ENSMUST00000100969.9
RIKEN cDNA 2810408A11 gene
chr3_+_32762656 0.56 ENSMUST00000029214.14
actin-like 6A
chr2_-_119039247 0.55 ENSMUST00000038439.4
DnaJ heat shock protein family (Hsp40) member C17
chr11_+_77923100 0.55 ENSMUST00000021187.12
dehydrogenase/reductase (SDR family) member 13

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
2.3 6.8 GO:0034118 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
1.3 3.9 GO:0060217 hemangioblast cell differentiation(GO:0060217)
1.3 5.1 GO:1902896 terminal web assembly(GO:1902896)
1.3 3.8 GO:0002215 defense response to nematode(GO:0002215)
1.1 6.4 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
1.0 7.3 GO:0060309 elastin catabolic process(GO:0060309)
1.0 11.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.8 4.1 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.8 6.1 GO:1901748 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.6 2.5 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.6 9.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.6 14.5 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.5 2.2 GO:0099541 diacylglycerol catabolic process(GO:0046340) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.5 1.6 GO:0010138 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) CMP metabolic process(GO:0046035)
0.5 6.3 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.5 3.0 GO:0097167 circadian regulation of translation(GO:0097167)
0.5 3.4 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.5 1.5 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.4 6.7 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.4 0.9 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.4 1.3 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.4 2.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.4 2.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.4 3.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.4 1.8 GO:0097048 dendritic cell apoptotic process(GO:0097048) neutrophil clearance(GO:0097350) regulation of dendritic cell apoptotic process(GO:2000668)
0.4 1.1 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
0.3 0.7 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.3 6.1 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.3 1.3 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.3 3.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 1.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3 1.0 GO:0002663 B cell tolerance induction(GO:0002514) regulation of tolerance induction to self antigen(GO:0002649) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.3 1.3 GO:0061386 closure of optic fissure(GO:0061386)
0.3 5.4 GO:0015809 arginine transport(GO:0015809)
0.3 2.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.3 2.4 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.3 1.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.3 2.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.3 0.8 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.3 1.6 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.3 2.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.3 1.5 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.3 0.8 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.2 1.0 GO:0019046 release from viral latency(GO:0019046)
0.2 2.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 1.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.2 1.6 GO:0035625 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.2 1.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 0.9 GO:1902943 regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
0.2 1.1 GO:0070543 response to linoleic acid(GO:0070543)
0.2 0.6 GO:0036245 cellular response to menadione(GO:0036245)
0.2 0.6 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.2 0.6 GO:0098749 cerebellar neuron development(GO:0098749)
0.2 0.6 GO:0010652 positive regulation of glomerular filtration(GO:0003104) atrial ventricular junction remodeling(GO:0003294) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 1.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 0.8 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.2 1.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 0.8 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 2.9 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2 0.5 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.2 0.5 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265) L-alanine catabolic process(GO:0042853) oxalic acid secretion(GO:0046724)
0.2 1.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 2.3 GO:0043589 skin morphogenesis(GO:0043589)
0.2 0.5 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 1.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 6.2 GO:0048821 erythrocyte development(GO:0048821)
0.1 0.8 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 7.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.3 GO:0021570 rhombomere 4 development(GO:0021570)
0.1 3.4 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.9 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 3.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
0.1 1.1 GO:2000193 positive regulation of fatty acid transport(GO:2000193)
0.1 0.6 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.1 2.2 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.3 GO:0061296 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.1 1.6 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.1 3.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.7 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 2.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.2 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 3.1 GO:0046039 GTP metabolic process(GO:0046039)
0.1 0.3 GO:0046016 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.1 3.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.5 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 1.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 3.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.3 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.8 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.5 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 6.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 2.6 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.2 GO:0042117 monocyte activation(GO:0042117)
0.0 0.7 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.1 GO:0061723 glycophagy(GO:0061723)
0.0 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.4 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 2.8 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 1.6 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 2.0 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 3.5 GO:0051028 mRNA transport(GO:0051028)
0.0 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) regulation of apoptotic DNA fragmentation(GO:1902510)
0.0 1.5 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.3 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.5 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.2 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.0 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 1.1 GO:0009409 response to cold(GO:0009409)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.2 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0 0.4 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.5 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 20.4 GO:0006508 proteolysis(GO:0006508)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0033193 Lsd1/2 complex(GO:0033193)
0.9 6.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.8 2.3 GO:0005584 collagen type I trimer(GO:0005584)
0.6 7.1 GO:0005796 Golgi lumen(GO:0005796)
0.5 4.5 GO:1990357 terminal web(GO:1990357)
0.4 11.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.4 2.4 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.3 7.2 GO:0042581 specific granule(GO:0042581)
0.3 2.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 5.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 1.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 0.7 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.2 14.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 1.6 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 2.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 1.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 1.9 GO:0000243 commitment complex(GO:0000243)
0.1 2.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 6.9 GO:0001772 immunological synapse(GO:0001772)
0.1 1.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 2.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 2.2 GO:0043196 varicosity(GO:0043196)
0.1 1.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.6 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 1.8 GO:0018995 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 7.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 3.0 GO:0043596 nuclear replication fork(GO:0043596)
0.1 4.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 1.0 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.0 GO:0036038 MKS complex(GO:0036038)
0.1 1.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 7.3 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 5.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.6 GO:0005916 fascia adherens(GO:0005916)
0.0 2.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 1.0 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 3.3 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.8 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 2.1 GO:0030667 secretory granule membrane(GO:0030667)
0.0 2.0 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 41.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 1.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 6.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 4.7 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.6 GO:0030315 T-tubule(GO:0030315)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.8 24.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.6 5.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.6 5.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.5 1.6 GO:0004461 lactose synthase activity(GO:0004461)
0.5 6.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.4 1.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.4 1.3 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.4 1.6 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.4 1.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.4 2.5 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.4 1.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 1.0 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.3 1.5 GO:0004111 creatine kinase activity(GO:0004111)
0.3 6.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 4.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 0.8 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.3 1.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.3 1.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.3 0.8 GO:0004371 glycerone kinase activity(GO:0004371) FAD-AMP lyase (cyclizing) activity(GO:0034012) triokinase activity(GO:0050354)
0.2 14.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 2.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 1.6 GO:0004849 uridine kinase activity(GO:0004849)
0.2 2.0 GO:0034711 inhibin binding(GO:0034711)
0.2 16.6 GO:0070888 E-box binding(GO:0070888)
0.2 1.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 2.0 GO:0008527 taste receptor activity(GO:0008527)
0.2 2.6 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.2 1.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 1.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 2.4 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 3.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.9 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 4.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 3.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 1.9 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 6.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.1 2.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.7 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.8 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 1.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.7 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 1.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 6.6 GO:0050699 WW domain binding(GO:0050699)
0.1 3.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.6 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 3.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.0 GO:0045545 syndecan binding(GO:0045545)
0.1 2.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.5 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.1 6.8 GO:0030507 spectrin binding(GO:0030507)
0.1 0.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.0 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 2.3 GO:0031489 myosin V binding(GO:0031489)
0.1 19.9 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 1.3 GO:0043495 protein anchor(GO:0043495)
0.1 1.8 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 7.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.3 GO:0010181 FMN binding(GO:0010181)
0.1 0.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.5 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 3.6 GO:0004601 peroxidase activity(GO:0004601)
0.1 0.7 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 2.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 2.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.2 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 3.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 6.5 GO:0002020 protease binding(GO:0002020)
0.0 0.1 GO:2001070 starch binding(GO:2001070)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 5.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 2.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 2.2 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 13.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 5.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 4.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 4.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 8.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 0.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 5.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.8 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 2.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.7 PID ATR PATHWAY ATR signaling pathway
0.0 2.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.0 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 6.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 1.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 6.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 14.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 5.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 1.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 5.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 5.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 5.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 9.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 3.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 3.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 1.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 2.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.7 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 2.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)