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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Tead1

Z-value: 1.23

Motif logo

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Transcription factors associated with Tead1

Gene Symbol Gene ID Gene Info
Tead1
ENSMUSG00000055320.19 Tead1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tead1mm39_v1_chr7_+_112278520_1122785320.829.5e-10Click!

Activity profile of Tead1 motif

Sorted Z-values of Tead1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tead1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_-_43558386 7.14 ENSMUST00000130353.2
Tln1
talin 1
chr7_-_33832640 5.11 ENSMUST00000038537.9
Wtip
WT1-interacting protein
chr12_+_85793313 4.13 ENSMUST00000040461.4
Flvcr2
feline leukemia virus subgroup C cellular receptor 2
chr11_+_61967821 3.58 ENSMUST00000092415.9
ENSMUST00000201015.4
ENSMUST00000202744.4
ENSMUST00000201723.4
ENSMUST00000202179.2
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr8_+_57964921 3.28 ENSMUST00000067925.8
Hmgb2
high mobility group box 2
chr7_-_143056252 3.23 ENSMUST00000010904.5
Phlda2
pleckstrin homology like domain, family A, member 2
chr15_+_6416229 3.08 ENSMUST00000110664.9
ENSMUST00000110663.9
ENSMUST00000161812.8
ENSMUST00000160134.8
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr18_+_50186349 2.86 ENSMUST00000148159.3
Tnfaip8
tumor necrosis factor, alpha-induced protein 8
chr11_-_115903504 2.60 ENSMUST00000021114.5
Galk1
galactokinase 1
chr11_-_100861713 2.51 ENSMUST00000060792.6
Cavin1
caveolae associated 1
chr8_+_57964956 2.45 ENSMUST00000210871.2
Hmgb2
high mobility group box 2
chr5_-_115438971 2.15 ENSMUST00000112090.2
Dynll1
dynein light chain LC8-type 1
chr2_+_156617329 2.05 ENSMUST00000088552.7
Myl9
myosin, light polypeptide 9, regulatory
chr18_+_50164043 1.93 ENSMUST00000145726.2
ENSMUST00000128377.2
Tnfaip8
tumor necrosis factor, alpha-induced protein 8
chr17_-_71575584 1.84 ENSMUST00000233148.2
Emilin2
elastin microfibril interfacer 2
chr18_+_62086122 1.83 ENSMUST00000051720.6
ENSMUST00000235860.2
Sh3tc2
SH3 domain and tetratricopeptide repeats 2
chr18_-_35795233 1.82 ENSMUST00000025209.12
ENSMUST00000096573.4
Spata24
spermatogenesis associated 24
chr17_+_47904441 1.78 ENSMUST00000182874.3
Ccnd3
cyclin D3
chr17_+_47904355 1.72 ENSMUST00000182209.8
Ccnd3
cyclin D3
chr18_-_35795175 1.64 ENSMUST00000236574.2
ENSMUST00000236971.2
Spata24
spermatogenesis associated 24
chr7_+_24603779 1.60 ENSMUST00000206906.2
ENSMUST00000206011.2
ENSMUST00000117419.8
ENSMUST00000205295.2
Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1
chr1_+_135764092 1.57 ENSMUST00000188028.7
ENSMUST00000178204.8
ENSMUST00000190451.7
ENSMUST00000189732.7
ENSMUST00000189355.7
Tnnt2
troponin T2, cardiac
chr2_-_60711706 1.43 ENSMUST00000164147.8
ENSMUST00000112509.2
Rbms1
RNA binding motif, single stranded interacting protein 1
chr15_+_54274151 1.41 ENSMUST00000036737.4
Colec10
collectin sub-family member 10
chr6_+_146789978 1.36 ENSMUST00000016631.14
ENSMUST00000203730.3
ENSMUST00000111623.9
Ppfibp1
PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr1_+_51328265 1.33 ENSMUST00000051572.8
Cavin2
caveolae associated 2
chr9_-_44624496 1.27 ENSMUST00000144251.8
ENSMUST00000156918.8
Phldb1
pleckstrin homology like domain, family B, member 1
chr15_+_6416079 1.23 ENSMUST00000080880.12
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr6_+_87405968 1.21 ENSMUST00000032125.7
Bmp10
bone morphogenetic protein 10
chr6_-_42350188 1.14 ENSMUST00000073387.5
ENSMUST00000204357.2
Epha1
Eph receptor A1
chr8_-_123278054 1.12 ENSMUST00000156333.9
ENSMUST00000067252.14
Piezo1
piezo-type mechanosensitive ion channel component 1
chr14_-_54815000 1.10 ENSMUST00000054487.10
Ajuba
ajuba LIM protein
chr4_-_139695337 1.09 ENSMUST00000105031.4
Klhdc7a
kelch domain containing 7A
chr5_+_136996713 1.03 ENSMUST00000001790.6
Cldn15
claudin 15
chr10_-_42152684 1.01 ENSMUST00000175881.8
ENSMUST00000056974.4
ENSMUST00000105502.8
ENSMUST00000105501.2
Foxo3
forkhead box O3
chr7_+_3340013 0.96 ENSMUST00000204541.2
Myadm
myeloid-associated differentiation marker
chr17_-_71309815 0.95 ENSMUST00000123686.8
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr14_-_70585874 0.95 ENSMUST00000152067.8
Slc39a14
solute carrier family 39 (zinc transporter), member 14
chr5_+_117501557 0.94 ENSMUST00000111959.2
Wsb2
WD repeat and SOCS box-containing 2
chr11_-_55310724 0.93 ENSMUST00000108858.8
ENSMUST00000141530.2
Sparc
secreted acidic cysteine rich glycoprotein
chr6_-_37419030 0.87 ENSMUST00000041093.6
Creb3l2
cAMP responsive element binding protein 3-like 2
chr4_-_62278761 0.85 ENSMUST00000107461.2
ENSMUST00000084528.10
Fkbp15
FK506 binding protein 15
chr17_+_69569184 0.85 ENSMUST00000224951.2
Epb41l3
erythrocyte membrane protein band 4.1 like 3
chr6_+_17306334 0.81 ENSMUST00000007799.13
ENSMUST00000115456.6
Cav1
caveolin 1, caveolae protein
chr6_+_120341055 0.80 ENSMUST00000005108.10
Kdm5a
lysine (K)-specific demethylase 5A
chr4_+_15265798 0.77 ENSMUST00000062684.9
Tmem64
transmembrane protein 64
chr7_-_109215754 0.72 ENSMUST00000084738.5
Denn2b
DENN domain containing 2B
chr3_+_31049896 0.72 ENSMUST00000108249.9
Prkci
protein kinase C, iota
chr11_-_5331734 0.66 ENSMUST00000172492.8
Znrf3
zinc and ring finger 3
chr2_-_120234539 0.66 ENSMUST00000090042.12
ENSMUST00000110729.2
ENSMUST00000090046.12
Tmem87a
transmembrane protein 87A
chr9_-_8004586 0.65 ENSMUST00000086580.12
ENSMUST00000065353.13
Yap1
yes-associated protein 1
chr19_-_57185928 0.61 ENSMUST00000111544.8
Ablim1
actin-binding LIM protein 1
chr1_+_135693818 0.61 ENSMUST00000038945.6
Phlda3
pleckstrin homology like domain, family A, member 3
chr4_-_129636073 0.61 ENSMUST00000066257.6
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chr17_+_5991555 0.60 ENSMUST00000115791.10
ENSMUST00000080283.13
Synj2
synaptojanin 2
chr16_-_38620688 0.59 ENSMUST00000057767.6
Upk1b
uroplakin 1B
chr7_-_28071919 0.59 ENSMUST00000119990.8
Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr15_+_78726824 0.58 ENSMUST00000059619.3
Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chr5_+_24631829 0.55 ENSMUST00000155598.8
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr7_-_28071658 0.54 ENSMUST00000094644.11
Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr14_+_5894220 0.53 ENSMUST00000063750.8
Rarb
retinoic acid receptor, beta
chr5_+_21850811 0.49 ENSMUST00000148873.8
ENSMUST00000072896.13
Armc10
armadillo repeat containing 10
chr8_+_129450766 0.49 ENSMUST00000149116.2
Itgb1
integrin beta 1 (fibronectin receptor beta)
chr19_-_23425757 0.49 ENSMUST00000036069.8
Mamdc2
MAM domain containing 2
chr8_+_122677231 0.48 ENSMUST00000093078.13
ENSMUST00000170857.8
ENSMUST00000026354.15
ENSMUST00000174753.8
ENSMUST00000172511.8
Banp
BTG3 associated nuclear protein
chr11_+_68961599 0.48 ENSMUST00000075980.12
ENSMUST00000094081.5
Tmem107
transmembrane protein 107
chr18_+_60659257 0.47 ENSMUST00000223984.2
ENSMUST00000025505.7
ENSMUST00000223590.2
Dctn4
dynactin 4
chr15_-_36283244 0.46 ENSMUST00000228358.2
ENSMUST00000022890.10
Rnf19a
ring finger protein 19A
chr1_-_155848917 0.46 ENSMUST00000138762.8
Cep350
centrosomal protein 350
chr6_-_128101275 0.46 ENSMUST00000127105.8
Tspan9
tetraspanin 9
chr4_-_62278673 0.42 ENSMUST00000084527.10
ENSMUST00000098033.10
Fkbp15
FK506 binding protein 15
chr7_-_65020655 0.41 ENSMUST00000032729.8
Tjp1
tight junction protein 1
chr5_+_103573367 0.41 ENSMUST00000048957.11
Ptpn13
protein tyrosine phosphatase, non-receptor type 13
chr17_-_71309012 0.39 ENSMUST00000128179.2
ENSMUST00000150456.2
ENSMUST00000233357.2
ENSMUST00000233417.2
Myl12a
Gm49909
myosin, light chain 12A, regulatory, non-sarcomeric
predicted gene, 49909
chr12_-_98703664 0.39 ENSMUST00000170188.8
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr19_-_57185988 0.38 ENSMUST00000099294.9
Ablim1
actin-binding LIM protein 1
chr11_-_85125889 0.36 ENSMUST00000018625.10
Appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr3_+_96011810 0.36 ENSMUST00000132980.8
ENSMUST00000138206.8
ENSMUST00000090785.9
ENSMUST00000035519.12
Otud7b
OTU domain containing 7B
chr1_+_189460461 0.36 ENSMUST00000097442.9
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr5_+_77099229 0.35 ENSMUST00000141687.2
Paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
chr19_-_57185808 0.35 ENSMUST00000111546.8
Ablim1
actin-binding LIM protein 1
chr19_-_57185861 0.35 ENSMUST00000111550.8
Ablim1
actin-binding LIM protein 1
chr11_+_115824108 0.34 ENSMUST00000140991.2
Sap30bp
SAP30 binding protein
chr18_+_44513547 0.34 ENSMUST00000202306.2
ENSMUST00000025350.10
Dcp2
decapping mRNA 2
chr9_-_65298934 0.33 ENSMUST00000068307.4
Kbtbd13
kelch repeat and BTB (POZ) domain containing 13
chr6_-_98319684 0.30 ENSMUST00000164491.3
Mdfic2
MyoD family inhibitor domain containing 2
chr17_-_36012932 0.28 ENSMUST00000166980.9
ENSMUST00000145900.8
Ddr1
discoidin domain receptor family, member 1
chr10_+_93476903 0.24 ENSMUST00000020204.5
Ntn4
netrin 4
chr1_-_160134873 0.23 ENSMUST00000193185.6
Rabgap1l
RAB GTPase activating protein 1-like
chr2_-_25982160 0.18 ENSMUST00000114159.9
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr14_-_123151162 0.17 ENSMUST00000160401.8
Ggact
gamma-glutamylamine cyclotransferase
chr2_+_20524587 0.17 ENSMUST00000114604.9
ENSMUST00000066509.10
Etl4
enhancer trap locus 4
chrX_-_103457431 0.17 ENSMUST00000033695.6
Abcb7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr6_+_34575435 0.17 ENSMUST00000079391.10
ENSMUST00000142512.8
ENSMUST00000115027.8
ENSMUST00000115026.8
Cald1
caldesmon 1
chr16_+_26281885 0.13 ENSMUST00000161053.8
ENSMUST00000115302.2
Cldn16
claudin 16
chr12_+_71184614 0.12 ENSMUST00000045907.16
2700049A03Rik
RIKEN cDNA 2700049A03 gene
chr11_+_62711057 0.12 ENSMUST00000055006.12
ENSMUST00000072639.10
Trim16
tripartite motif-containing 16
chr3_+_122304778 0.11 ENSMUST00000198659.2
Bcar3
breast cancer anti-estrogen resistance 3
chr17_-_48145466 0.11 ENSMUST00000066368.13
Mdfi
MyoD family inhibitor
chr2_+_91287846 0.07 ENSMUST00000028689.4
Lrp4
low density lipoprotein receptor-related protein 4
chr18_-_9450097 0.06 ENSMUST00000053917.6
Ccny
cyclin Y
chr5_-_86616849 0.06 ENSMUST00000101073.3
Tmprss11a
transmembrane protease, serine 11a
chr5_-_135518098 0.06 ENSMUST00000201998.2
Hip1
huntingtin interacting protein 1
chr6_-_119173348 0.04 ENSMUST00000187474.7
ENSMUST00000187940.7
Cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr7_+_140796096 0.02 ENSMUST00000153081.2
Rassf7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr11_+_115865535 0.02 ENSMUST00000021107.14
ENSMUST00000169928.8
ENSMUST00000106461.8
Itgb4
integrin beta 4
chr6_-_128277701 0.00 ENSMUST00000143004.2
ENSMUST00000006311.13
ENSMUST00000112157.4
ENSMUST00000133118.2
Tead4
TEA domain family member 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.9 2.6 GO:0006059 hexitol metabolic process(GO:0006059) glycolytic process from galactose(GO:0061623)
0.7 4.3 GO:0035026 leading edge cell differentiation(GO:0035026)
0.6 2.5 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.6 5.7 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.6 8.0 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.6 5.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.4 1.6 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 1.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 0.7 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 0.6 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.2 0.8 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.2 2.1 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.8 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 0.5 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.1 1.0 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.1 3.5 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 1.2 GO:1903242 regulation of cardiac muscle adaptation(GO:0010612) positive regulation of sarcomere organization(GO:0060298) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.1 1.3 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.5 GO:0040010 positive regulation of growth rate(GO:0040010)
0.1 0.7 GO:0060242 contact inhibition(GO:0060242)
0.1 0.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 1.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.2 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.1 4.8 GO:0032611 interleukin-1 beta production(GO:0032611)
0.1 0.4 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.7 GO:0035089 establishment of apical/basal cell polarity(GO:0035089)
0.0 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 1.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0071044 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) histone mRNA catabolic process(GO:0071044)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 2.0 GO:0070527 platelet aggregation(GO:0070527)
0.0 1.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.1 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.9 GO:0006826 iron ion transport(GO:0006826)
0.0 0.4 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.9 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.0 0.9 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 0.7 GO:0071148 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.2 0.5 GO:0034665 integrin alpha1-beta1 complex(GO:0034665) integrin alpha7-beta1 complex(GO:0034677) integrin alpha10-beta1 complex(GO:0034680) integrin alpha11-beta1 complex(GO:0034681)
0.1 2.1 GO:1904115 axon cytoplasm(GO:1904115)
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.1 3.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 6.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.7 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 3.2 GO:0005581 collagen trimer(GO:0005581)
0.0 1.3 GO:0099738 cell cortex region(GO:0099738)
0.0 0.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 7.2 GO:0001726 ruffle(GO:0001726)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 5.7 GO:0000793 condensed chromosome(GO:0000793)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.2 GO:0005901 caveola(GO:0005901)
0.0 1.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.1 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.1 GO:0015232 heme transporter activity(GO:0015232)
0.6 2.6 GO:0004335 galactokinase activity(GO:0004335)
0.6 5.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.5 7.1 GO:0030274 LIM domain binding(GO:0030274)
0.4 2.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 4.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.6 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.2 0.8 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 1.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 2.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 1.2 GO:0031433 telethonin binding(GO:0031433)
0.1 1.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 4.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 1.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.9 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 3.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 1.0 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 1.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 3.0 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 3.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 3.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 2.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 7.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 4.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 2.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 3.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 0.7 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 1.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane