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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Tfap2b

Z-value: 1.74

Motif logo

Transcription factors associated with Tfap2b

Gene Symbol Gene ID Gene Info
ENSMUSG00000025927.14 Tfap2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfap2bmm39_v1_chr1_+_19282278_192823300.124.9e-01Click!

Activity profile of Tfap2b motif

Sorted Z-values of Tfap2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_76756772 24.73 ENSMUST00000166101.2
spectrin beta, erythrocytic
chr11_-_102255999 18.67 ENSMUST00000006749.10
solute carrier family 4 (anion exchanger), member 1
chr2_-_131001916 12.72 ENSMUST00000103188.10
ENSMUST00000133602.8
ENSMUST00000028800.12
RIKEN cDNA 1700037H04 gene
chr1_-_132294807 10.93 ENSMUST00000136828.3
transmembrane and coiled-coil domains 2
chr11_-_70146156 8.47 ENSMUST00000108574.3
ENSMUST00000000329.9
arachidonate 12-lipoxygenase
chr3_-_84387700 8.15 ENSMUST00000194027.2
ENSMUST00000107689.7
FH2 domain containing 1
chr7_-_45175570 7.72 ENSMUST00000167273.2
ENSMUST00000042105.11
protein phosphatase 1, regulatory subunit 15A
chr7_+_25386418 7.06 ENSMUST00000002678.10
transforming growth factor, beta 1
chr4_-_140501507 6.39 ENSMUST00000026381.7
peptidyl arginine deiminase, type IV
chr13_-_55635851 6.05 ENSMUST00000109921.9
ENSMUST00000109923.9
ENSMUST00000021950.15
drebrin 1
chr17_+_33774681 5.84 ENSMUST00000087605.13
ENSMUST00000174695.2
myosin IF
chr8_+_106024294 5.24 ENSMUST00000015003.10
E2F transcription factor 4
chr2_+_119572770 5.02 ENSMUST00000028758.8
inositol 1,4,5-trisphosphate 3-kinase A
chr7_-_97811525 4.35 ENSMUST00000107112.2
calpain 5
chr4_-_133694607 3.99 ENSMUST00000105893.8
high mobility group nucleosomal binding domain 2
chr3_-_137687284 3.88 ENSMUST00000136613.4
ENSMUST00000029806.13
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
chr2_-_30720345 3.56 ENSMUST00000041726.4
ankyrin repeat and SOCS box-containing 6
chr11_-_99383938 3.50 ENSMUST00000006969.8
keratin 23
chr4_-_133694543 3.46 ENSMUST00000123234.8
high mobility group nucleosomal binding domain 2
chr19_-_6065872 3.37 ENSMUST00000164843.10
calpain 1
chr6_-_83031358 3.21 ENSMUST00000113962.8
ENSMUST00000089645.13
ENSMUST00000113963.8
HtrA serine peptidase 2
chr17_+_35133435 3.17 ENSMUST00000007249.15
solute carrier family 44, member 4
chr6_+_91492910 2.98 ENSMUST00000040607.6
LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
chr5_-_115438971 2.87 ENSMUST00000112090.2
dynein light chain LC8-type 1
chr4_-_133695204 2.86 ENSMUST00000100472.10
ENSMUST00000136327.2
high mobility group nucleosomal binding domain 2
chr18_+_60907668 2.84 ENSMUST00000025511.11
ribosomal protein S14
chr18_+_60907698 2.81 ENSMUST00000118551.8
ribosomal protein S14
chr5_-_115439016 2.77 ENSMUST00000009157.4
dynein light chain LC8-type 1
chr6_+_91492988 2.73 ENSMUST00000206947.2
LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
chr9_+_54606144 2.73 ENSMUST00000120452.8
DnaJ heat shock protein family (Hsp40) member A4
chr19_+_6952580 2.68 ENSMUST00000237084.2
ENSMUST00000236218.2
ENSMUST00000237235.2
protein phosphatase 1, regulatory inhibitor subunit 14B
chr2_+_30176395 2.64 ENSMUST00000064447.12
nucleoporin 188
chr6_-_124710030 2.63 ENSMUST00000173647.2
protein tyrosine phosphatase, non-receptor type 6
chr7_+_43896146 2.61 ENSMUST00000055858.14
ENSMUST00000137702.8
ENSMUST00000188111.7
ENSMUST00000185481.7
ENSMUST00000146155.8
ENSMUST00000107949.8
ENSMUST00000084937.11
ENSMUST00000107950.9
ENSMUST00000107948.8
ENSMUST00000187524.7
ENSMUST00000137742.8
ENSMUST00000125318.3
RIKEN cDNA 2410002F23 gene
predicted gene 28496
chr17_+_43327412 2.61 ENSMUST00000024708.6
tumor necrosis factor receptor superfamily, member 21
chr7_+_141027763 2.60 ENSMUST00000106003.2
ribosomal protein, large P2
chr19_-_6065415 2.58 ENSMUST00000237519.2
calpain 1
chr11_+_121150798 2.56 ENSMUST00000106113.2
forkhead box K2
chrX_+_9138995 2.54 ENSMUST00000015486.7
X-linked Kx blood group
chr9_+_118881838 2.54 ENSMUST00000051386.13
ENSMUST00000074734.13
villin-like
chr9_-_50256268 2.53 ENSMUST00000076364.6
ribosomal protein L10, pseudogene 3
chr17_+_34808772 2.51 ENSMUST00000038244.15
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr3_-_132655954 2.51 ENSMUST00000042744.16
ENSMUST00000117811.8
nephronectin
chr17_+_29709723 2.50 ENSMUST00000024811.9
proviral integration site 1
chr2_-_154411765 2.48 ENSMUST00000103145.11
E2F transcription factor 1
chr2_-_11506893 2.46 ENSMUST00000114845.10
ENSMUST00000171188.9
ENSMUST00000179584.8
ENSMUST00000028114.13
ENSMUST00000114846.9
ENSMUST00000170196.9
ENSMUST00000191668.6
ENSMUST00000049849.12
ENSMUST00000114844.8
ENSMUST00000100411.4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr12_+_85733415 2.38 ENSMUST00000040536.6
basic leucine zipper transcription factor, ATF-like
chr19_+_6952319 2.38 ENSMUST00000070850.8
protein phosphatase 1, regulatory inhibitor subunit 14B
chr17_+_34809132 2.36 ENSMUST00000173772.2
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr19_-_53026965 2.35 ENSMUST00000183274.8
ENSMUST00000182097.2
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr2_+_158610003 2.33 ENSMUST00000029183.3
family with sequence similarity 83, member D
chr4_-_133695264 2.31 ENSMUST00000102553.11
high mobility group nucleosomal binding domain 2
chr5_-_36555434 2.21 ENSMUST00000037370.14
ENSMUST00000070720.8
sortilin-related VPS10 domain containing receptor 2
chr5_+_142946598 2.21 ENSMUST00000129306.4
fascin actin-bundling protein 1
chr3_-_132655804 2.20 ENSMUST00000117164.8
ENSMUST00000093971.5
ENSMUST00000042729.16
nephronectin
chr12_-_111638722 2.19 ENSMUST00000001304.9
creatine kinase, brain
chr7_+_141027557 2.18 ENSMUST00000106004.8
ribosomal protein, large P2
chr16_-_21982049 2.15 ENSMUST00000100052.11
insulin-like growth factor 2 mRNA binding protein 2
chr14_-_30329765 2.13 ENSMUST00000112207.8
ENSMUST00000112206.8
ENSMUST00000112202.8
ENSMUST00000112203.2
protein kinase C, delta
chr8_+_85449632 2.09 ENSMUST00000098571.5
RIKEN cDNA G430095P16 gene
chr13_+_13612136 2.08 ENSMUST00000005532.9
nidogen 1
chr10_-_59787646 2.08 ENSMUST00000020308.5
DNA-damage-inducible transcript 4
chr17_+_29020064 2.06 ENSMUST00000004985.11
bromodomain and PHD finger containing, 3
chr8_+_106331866 2.06 ENSMUST00000043531.10
RHO family interacting cell polarization regulator 1
chr10_-_75757393 2.05 ENSMUST00000121304.2
ENSMUST00000000925.10
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
chrX_+_70600481 2.03 ENSMUST00000123100.2
high mobility group box 3
chr6_-_124710084 2.02 ENSMUST00000112484.10
protein tyrosine phosphatase, non-receptor type 6
chr11_-_58059293 2.01 ENSMUST00000172035.8
ENSMUST00000035604.13
ENSMUST00000102711.9
gem nuclear organelle associated protein 5
chr6_+_88442391 2.01 ENSMUST00000032165.16
RuvB-like protein 1
chr15_+_61859255 2.01 ENSMUST00000160009.2
myelocytomatosis oncogene
chr11_+_60590584 2.01 ENSMUST00000108719.4
LLGL1 scribble cell polarity complex component
chr15_-_97729341 1.98 ENSMUST00000079838.14
ENSMUST00000118294.8
histone deacetylase 7
chr8_+_72050292 1.98 ENSMUST00000143662.8
niban apoptosis regulator 3
chr11_+_60590498 1.96 ENSMUST00000052346.10
LLGL1 scribble cell polarity complex component
chr15_-_79571977 1.86 ENSMUST00000023061.7
Josephin domain containing 1
chr16_+_58490625 1.85 ENSMUST00000060077.7
coproporphyrinogen oxidase
chr8_+_79754980 1.80 ENSMUST00000087927.11
ENSMUST00000098614.9
zinc finger protein 827
chrX_-_9335525 1.73 ENSMUST00000015484.10
cytochrome b-245, beta polypeptide
chr8_+_105267431 1.65 ENSMUST00000056051.11
carbonic anhydrase 7
chr9_-_106762818 1.64 ENSMUST00000185707.2
RNA binding motif protein 15B
chr2_-_181335518 1.61 ENSMUST00000108776.8
ENSMUST00000108771.2
regulator of G-protein signaling 19
chr11_+_69856222 1.60 ENSMUST00000018713.13
claudin 7
chr7_-_45116316 1.60 ENSMUST00000033093.10
BCL2-associated X protein
chr11_+_32483290 1.57 ENSMUST00000102821.4
serine/threonine kinase 10
chr15_+_102427149 1.55 ENSMUST00000146756.8
ENSMUST00000142194.3
TARBP2, RISC loading complex RNA binding subunit
chr7_-_45116216 1.53 ENSMUST00000210392.2
ENSMUST00000211365.2
BCL2-associated X protein
chr17_-_46593917 1.52 ENSMUST00000225359.2
ENSMUST00000225080.2
ENSMUST00000225943.2
ENSMUST00000012440.14
ENSMUST00000164342.10
ENSMUST00000180283.2
tight junction associated protein 1
chr19_-_6065799 1.51 ENSMUST00000235138.2
calpain 1
chr8_+_40876827 1.51 ENSMUST00000049389.11
ENSMUST00000128166.8
ENSMUST00000167766.2
zinc finger, DHHC domain containing 2
chr11_+_102080489 1.45 ENSMUST00000078975.8
glucose 6 phosphatase, catalytic, 3
chr15_-_103242697 1.43 ENSMUST00000229373.2
zinc finger protein 385A
chr8_+_106412905 1.40 ENSMUST00000213019.2
capping protein regulator and myosin 1 linker 2
chr2_+_30176418 1.32 ENSMUST00000138666.8
ENSMUST00000113634.3
nucleoporin 188
chr19_+_6451667 1.30 ENSMUST00000113471.3
ENSMUST00000113469.3
RAS, guanyl releasing protein 2
chr14_+_30973407 1.30 ENSMUST00000022458.11
Brca1 associated protein 1
chr5_+_31070739 1.29 ENSMUST00000031055.8
elastin microfibril interfacer 1
chr2_+_38229270 1.28 ENSMUST00000143783.9
LIM homeobox protein 2
chr9_+_121589044 1.27 ENSMUST00000093772.4
zinc finger protein 651
chr7_+_89780785 1.23 ENSMUST00000208684.2
phosphatidylinositol binding clathrin assembly protein
chr7_+_24990596 1.21 ENSMUST00000164820.2
capicua transcriptional repressor
chr16_-_20245071 1.20 ENSMUST00000115547.9
ENSMUST00000096199.5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr7_-_45116197 1.20 ENSMUST00000211195.2
ENSMUST00000210019.2
BCL2-associated X protein
chr8_+_117983803 1.18 ENSMUST00000166750.9
c-Maf inducing protein
chr2_-_91854844 1.12 ENSMUST00000028663.5
cAMP responsive element binding protein 3-like 1
chr5_+_138192536 1.12 ENSMUST00000057773.5
metallo-beta-lactamase domain containing 1
chr16_-_20245138 1.10 ENSMUST00000079158.13
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr2_+_155798457 1.10 ENSMUST00000109619.9
ENSMUST00000094421.11
ENSMUST00000039994.14
ENSMUST00000151569.8
ENSMUST00000109618.2
centrosomal protein 250
chr12_-_15866763 1.09 ENSMUST00000020922.8
ENSMUST00000221215.2
ENSMUST00000221518.2
tribbles pseudokinase 2
chr1_+_86454431 1.09 ENSMUST00000045897.15
ENSMUST00000186255.7
ENSMUST00000188699.7
prothymosin alpha
chr17_-_48189815 1.06 ENSMUST00000154108.2
forkhead box P4
chr10_-_127047396 1.05 ENSMUST00000013970.9
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr8_+_111448092 1.04 ENSMUST00000052457.15
MTSS I-BAR domain containing 2
chr17_-_13211374 1.02 ENSMUST00000159551.8
ENSMUST00000160781.8
Wilms tumour 1-associating protein
chr7_+_24981604 1.01 ENSMUST00000163320.8
ENSMUST00000005578.13
capicua transcriptional repressor
chr7_+_127078371 0.99 ENSMUST00000205432.3
fibrosin
chr11_-_102187445 0.99 ENSMUST00000107132.3
ENSMUST00000073234.9
ataxin 7-like 3
chr10_-_119075910 0.99 ENSMUST00000020315.13
cullin associated and neddylation disassociated 1
chrX_+_149830166 0.97 ENSMUST00000026296.8
FYVE, RhoGEF and PH domain containing 1
chr15_-_38300937 0.96 ENSMUST00000227920.2
ENSMUST00000074043.7
ENSMUST00000228416.2
Kruppel-like factor 10
chr17_+_36152383 0.95 ENSMUST00000082337.13
mediator of DNA damage checkpoint 1
chr6_+_38528269 0.95 ENSMUST00000163047.8
ENSMUST00000161538.8
ENSMUST00000057692.11
LUC7-like 2 (S. cerevisiae)
chr19_+_38043446 0.88 ENSMUST00000236044.2
ENSMUST00000116506.8
ENSMUST00000096096.12
ENSMUST00000169673.3
centrosomal protein 55
chr13_-_53440087 0.88 ENSMUST00000021918.10
receptor tyrosine kinase-like orphan receptor 2
chr1_+_86454511 0.88 ENSMUST00000188533.2
prothymosin alpha
chr4_+_59035088 0.83 ENSMUST00000041160.13
guanine nucleotide binding protein (G protein), gamma 10
chr4_-_136563154 0.82 ENSMUST00000105846.9
ENSMUST00000059287.14
ENSMUST00000105845.9
Eph receptor B2
chr5_-_103777145 0.81 ENSMUST00000031263.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr14_-_86986541 0.81 ENSMUST00000226254.2
diaphanous related formin 3
chr19_+_5790918 0.80 ENSMUST00000081496.6
latent transforming growth factor beta binding protein 3
chr13_+_48816466 0.79 ENSMUST00000021813.5
BarH-like homeobox 1
chr17_-_71156639 0.77 ENSMUST00000134654.2
ENSMUST00000172229.8
ENSMUST00000127719.2
TGFB-induced factor homeobox 1
chr7_-_126625657 0.76 ENSMUST00000205568.2
MYC-associated zinc finger protein (purine-binding transcription factor)
chr4_+_132903646 0.76 ENSMUST00000105912.2
WASP family, member 2
chr12_+_108376801 0.72 ENSMUST00000054955.14
echinoderm microtubule associated protein like 1
chr2_+_14828903 0.71 ENSMUST00000193800.6
calcium channel, voltage-dependent, beta 2 subunit
chr7_-_126046814 0.71 ENSMUST00000146973.2
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr7_+_28834276 0.69 ENSMUST00000161522.8
ENSMUST00000204845.3
ENSMUST00000205027.3
ENSMUST00000204194.3
ENSMUST00000203070.3
ENSMUST00000203380.3
RAS guanyl releasing protein 4
chr7_-_45045097 0.68 ENSMUST00000211121.2
ENSMUST00000074575.11
small nuclear ribonucleoprotein 70 (U1)
chr15_-_101833160 0.67 ENSMUST00000023797.8
keratin 4
chr11_-_115977755 0.67 ENSMUST00000074628.13
ENSMUST00000106444.4
WW domain binding protein 2
chr1_+_86082474 0.66 ENSMUST00000113309.9
ENSMUST00000186509.7
ENSMUST00000027434.15
ENSMUST00000131412.8
armadillo repeat containing 9
chrX_+_48559327 0.64 ENSMUST00000114904.10
Rho GTPase activating protein 36
chr14_-_24054927 0.64 ENSMUST00000145596.3
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr11_+_107438751 0.61 ENSMUST00000100305.8
ENSMUST00000075012.8
ENSMUST00000106746.8
helicase with zinc finger domain
chr15_+_103411461 0.61 ENSMUST00000023132.5
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr11_-_75345482 0.60 ENSMUST00000173320.8
WD repeat domain 81
chr19_-_42741148 0.59 ENSMUST00000236659.2
ENSMUST00000076505.4
pyridine nucleotide-disulphide oxidoreductase domain 2
chr1_-_96799832 0.58 ENSMUST00000071985.6
solute carrier organic anion transporter family, member 4C1
chr9_+_118881926 0.58 ENSMUST00000131647.2
villin-like
chr8_-_123404811 0.57 ENSMUST00000006525.14
ENSMUST00000064674.13
CBFA2/RUNX1 translocation partner 3
chr11_-_75069618 0.57 ENSMUST00000071562.3
candidate tumor suppressor in ovarian cancer 2
chr17_+_83522700 0.56 ENSMUST00000170794.8
protein kinase domain containing, cytoplasmic
chr17_-_46593574 0.56 ENSMUST00000224230.2
ENSMUST00000225288.2
tight junction associated protein 1
chr17_-_32503689 0.55 ENSMUST00000127893.8
bromodomain containing 4
chr3_-_8732316 0.55 ENSMUST00000042412.5
hairy/enhancer-of-split related with YRPW motif 1
chr10_-_81201642 0.55 ENSMUST00000020456.5
RIKEN cDNA 4930404N11 gene
chr2_-_93787441 0.55 ENSMUST00000099689.5
predicted gene 13889
chr8_+_70354828 0.54 ENSMUST00000050373.7
testis-specific serine kinase 6
chrX_+_158410229 0.52 ENSMUST00000112456.9
SH3-domain kinase binding protein 1
chr7_-_127048280 0.50 ENSMUST00000053392.11
zinc finger protein 689
chr6_+_124986627 0.50 ENSMUST00000046064.17
ENSMUST00000152752.8
ENSMUST00000088308.10
ENSMUST00000112425.8
ENSMUST00000084275.12
zinc finger protein 384
chr7_-_4687916 0.48 ENSMUST00000206306.2
ENSMUST00000205952.2
ENSMUST00000079970.6
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr11_+_69909245 0.48 ENSMUST00000231415.2
ENSMUST00000108588.9
discs large MAGUK scaffold protein 4
chr1_-_143578542 0.47 ENSMUST00000018337.9
cell division cycle 73, Paf1/RNA polymerase II complex component
chr9_-_96993169 0.46 ENSMUST00000085206.11
solute carrier family 25, member 36
chr11_+_55360502 0.46 ENSMUST00000018727.4
GTPase activating protein (SH3 domain) binding protein 1
chr18_+_3507917 0.46 ENSMUST00000025075.3
BMP and activin membrane-bound inhibitor
chr11_-_94133527 0.44 ENSMUST00000061469.4
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr11_+_35011953 0.44 ENSMUST00000069837.4
slit guidance ligand 3
chr19_-_53932581 0.44 ENSMUST00000236885.2
ENSMUST00000236098.2
ENSMUST00000236370.2
BBSome interacting protein 1
chr7_+_86645323 0.44 ENSMUST00000233714.2
ENSMUST00000233648.2
ENSMUST00000164462.3
ENSMUST00000233730.2
vomeronasal 2, receptor 79
chr13_+_24685508 0.43 ENSMUST00000238974.2
RHO family interacting cell polarization regulator 2
chr12_+_102094977 0.43 ENSMUST00000159329.8
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr17_-_55932192 0.43 ENSMUST00000168440.3
vomeronasal 2, receptor 118
chr12_+_108376884 0.42 ENSMUST00000109857.8
echinoderm microtubule associated protein like 1
chr9_+_35819708 0.41 ENSMUST00000176049.2
ENSMUST00000176153.2
prostate and testis expressed 13
chr17_-_36011378 0.41 ENSMUST00000119825.8
discoidin domain receptor family, member 1
chr17_-_80369762 0.40 ENSMUST00000061331.14
heterogeneous nuclear ribonucleoprotein L-like
chr6_+_8209216 0.40 ENSMUST00000040017.8
meiosis regulator for oocyte development
chr18_+_61058684 0.39 ENSMUST00000102888.10
ENSMUST00000025519.11
calcium/calmodulin-dependent protein kinase II alpha
chr8_-_123405392 0.38 ENSMUST00000134045.2
CBFA2/RUNX1 translocation partner 3
chr6_+_7844759 0.38 ENSMUST00000040159.6
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr12_+_84116099 0.37 ENSMUST00000046422.11
ENSMUST00000072505.5
acyl-CoA thioesterase 5
chr9_+_38288382 0.36 ENSMUST00000214865.2
olfactory receptor 251
chr2_-_155199300 0.34 ENSMUST00000165234.2
ENSMUST00000077626.13
phosphatidylinositol glycan anchor biosynthesis, class U
chr7_-_126625739 0.34 ENSMUST00000205461.2
MYC-associated zinc finger protein (purine-binding transcription factor)
chr11_-_50183129 0.33 ENSMUST00000059458.5
mastermind like transcriptional coactivator 1
chr15_+_99476935 0.32 ENSMUST00000023752.6
aquaporin 2
chr9_+_110673565 0.31 ENSMUST00000176403.8
protease, serine 46
chr8_+_96058907 0.31 ENSMUST00000034245.16
U6 snRNA biogenesis 1
chr2_-_93787383 0.30 ENSMUST00000148314.3
predicted gene 13889
chr3_-_108322868 0.30 ENSMUST00000090558.10
cadherin, EGF LAG seven-pass G-type receptor 2
chr13_+_55097200 0.29 ENSMUST00000026994.14
ENSMUST00000109994.9
unc-5 netrin receptor A
chr16_-_20244631 0.29 ENSMUST00000077867.10
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr3_+_141170941 0.28 ENSMUST00000106236.9
unc-5 netrin receptor C
chr19_-_53932867 0.26 ENSMUST00000235688.2
ENSMUST00000235348.2
BBSome interacting protein 1
chr13_-_54616618 0.23 ENSMUST00000026990.6
THO complex 3
chrX_+_48559432 0.22 ENSMUST00000042444.7
Rho GTPase activating protein 36
chr6_+_38528738 0.22 ENSMUST00000161227.8
LUC7-like 2 (S. cerevisiae)
chr1_+_39940043 0.22 ENSMUST00000168431.7
ENSMUST00000163854.9
mitogen-activated protein kinase kinase kinase kinase 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
2.4 7.1 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of hyaluronan biosynthetic process(GO:1900126)
2.0 6.1 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
1.7 8.5 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
1.4 4.3 GO:0032976 release of matrix enzymes from mitochondria(GO:0032976) B cell receptor apoptotic signaling pathway(GO:1990117)
1.3 6.4 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
1.1 3.2 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
1.1 3.2 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.9 4.7 GO:0097195 pilomotor reflex(GO:0097195)
0.8 0.8 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.7 2.7 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.6 2.5 GO:2001107 negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.6 2.5 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.6 16.5 GO:0015701 bicarbonate transport(GO:0015701)
0.6 4.6 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.6 26.6 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.6 4.0 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.5 2.1 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.5 2.1 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.5 2.0 GO:0090096 lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.5 1.4 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.4 2.5 GO:0031133 regulation of axon diameter(GO:0031133)
0.4 7.5 GO:0016540 protein autoprocessing(GO:0016540)
0.4 1.7 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.4 2.0 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.4 12.6 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.4 5.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4 5.0 GO:0006020 inositol metabolic process(GO:0006020)
0.4 5.6 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.4 1.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.4 1.4 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.3 2.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.3 1.3 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.3 5.8 GO:0043312 neutrophil degranulation(GO:0043312)
0.3 2.5 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.3 0.6 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.3 0.8 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.3 5.2 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.3 1.6 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423) negative regulation of defense response to virus by host(GO:0050689)
0.2 2.2 GO:0030035 microspike assembly(GO:0030035)
0.2 0.7 GO:0051659 maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
0.2 2.3 GO:0010815 bradykinin catabolic process(GO:0010815)
0.2 4.9 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 1.1 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.2 1.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.2 1.7 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.2 1.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2 3.0 GO:0045820 negative regulation of glycolytic process(GO:0045820)
0.2 5.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 1.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 0.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 0.9 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.2 5.9 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.2 2.7 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 2.4 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.2 0.3 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.4 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.1 1.4 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 2.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 9.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 0.4 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1 2.0 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.3 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.6 GO:0060082 response to carbon monoxide(GO:0034465) eye blink reflex(GO:0060082)
0.1 1.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 1.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 1.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 1.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 1.1 GO:1901249 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.1 0.5 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.7 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.6 GO:0090005 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 4.8 GO:0006414 translational elongation(GO:0006414)
0.1 2.0 GO:0043486 histone exchange(GO:0043486)
0.1 1.0 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.9 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 0.3 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.3 GO:0070384 growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 2.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 1.0 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 2.3 GO:0051310 metaphase plate congression(GO:0051310)
0.0 1.0 GO:0016578 histone deubiquitination(GO:0016578)
0.0 3.1 GO:0051693 actin filament capping(GO:0051693)
0.0 0.5 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.7 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 1.0 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.0 1.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.6 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.1 GO:0045186 zonula adherens assembly(GO:0045186)
0.0 0.5 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.8 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 1.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.6 GO:0097186 amelogenesis(GO:0097186)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 1.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.0 0.1 GO:0046959 habituation(GO:0046959)
0.0 0.8 GO:0048536 spleen development(GO:0048536)
0.0 1.5 GO:0051028 mRNA transport(GO:0051028)
0.0 0.1 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0042414 epinephrine metabolic process(GO:0042414)
0.0 0.8 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 24.7 GO:0008091 spectrin(GO:0008091)
1.5 6.1 GO:1902737 dendritic filopodium(GO:1902737)
1.4 4.3 GO:0097144 BAX complex(GO:0097144)
0.6 5.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.6 4.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.5 4.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.5 7.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.5 2.5 GO:0035189 Rb-E2F complex(GO:0035189)
0.4 2.2 GO:0044393 microspike(GO:0044393)
0.4 4.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 0.7 GO:0031673 H zone(GO:0031673)
0.3 4.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 5.6 GO:1904115 axon cytoplasm(GO:1904115)
0.2 2.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 2.0 GO:0097255 R2TP complex(GO:0097255)
0.2 3.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 1.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 2.0 GO:0032797 SMN complex(GO:0032797)
0.1 1.0 GO:0036396 MIS complex(GO:0036396)
0.1 1.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.1 17.9 GO:0014704 intercalated disc(GO:0014704)
0.1 1.4 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.4 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.1 1.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.4 GO:0060171 stereocilium membrane(GO:0060171)
0.1 3.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.9 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 2.1 GO:0071564 npBAF complex(GO:0071564)
0.1 5.8 GO:0031941 filamentous actin(GO:0031941)
0.1 2.1 GO:0005605 basal lamina(GO:0005605)
0.1 1.0 GO:0090543 Flemming body(GO:0090543)
0.1 3.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 4.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.7 GO:0034464 BBSome(GO:0034464)
0.1 1.0 GO:0000124 SAGA complex(GO:0000124)
0.1 1.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 7.1 GO:0005902 microvillus(GO:0005902)
0.1 0.3 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 1.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.6 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 2.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 4.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 1.3 GO:0008305 integrin complex(GO:0008305)
0.0 0.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.8 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 6.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.2 GO:0005776 autophagosome(GO:0005776)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.5 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
1.4 5.7 GO:0030629 U6 snRNA 3'-end binding(GO:0030629)
1.3 6.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.2 7.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.0 41.9 GO:0030506 ankyrin binding(GO:0030506)
0.7 2.0 GO:0030622 U4atac snRNA binding(GO:0030622)
0.6 5.0 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.5 2.1 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.5 5.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.4 4.3 GO:0051434 BH3 domain binding(GO:0051434)
0.4 1.3 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.4 1.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.4 11.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 1.4 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.4 4.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.4 6.0 GO:0005522 profilin binding(GO:0005522)
0.3 2.4 GO:0004111 creatine kinase activity(GO:0004111)
0.3 5.6 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.3 1.9 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 2.1 GO:0043237 laminin-1 binding(GO:0043237)
0.2 1.6 GO:0070883 pre-miRNA binding(GO:0070883)
0.2 1.7 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 1.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 0.6 GO:0035939 microsatellite binding(GO:0035939)
0.2 7.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 1.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 5.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 6.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 4.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 2.1 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 5.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.6 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 1.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 3.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.1 2.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 2.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.5 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 1.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.6 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.7 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 0.7 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.3 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.4 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 1.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.8 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.5 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 2.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 1.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 4.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 5.2 GO:0051015 actin filament binding(GO:0051015)
0.0 5.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 3.2 GO:0005178 integrin binding(GO:0005178)
0.0 2.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 7.3 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 2.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.0 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.4 7.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 6.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 4.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 2.5 PID IL5 PATHWAY IL5-mediated signaling events
0.1 6.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 4.0 PID MYC PATHWAY C-MYC pathway
0.1 4.6 PID EPO PATHWAY EPO signaling pathway
0.1 5.9 PID BMP PATHWAY BMP receptor signaling
0.1 2.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 7.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 3.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 3.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.0 PID ATM PATHWAY ATM pathway
0.0 2.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 2.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 24.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 14.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.3 5.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 8.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 4.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 2.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 2.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 5.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 4.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 2.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 3.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 5.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 2.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 11.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 4.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 0.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 1.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 2.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 2.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 2.2 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation