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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Tfcp2

Z-value: 3.93

Motif logo

Transcription factors associated with Tfcp2

Gene Symbol Gene ID Gene Info
ENSMUSG00000009733.10 Tfcp2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfcp2mm39_v1_chr15_-_100449839_1004498920.421.1e-02Click!

Activity profile of Tfcp2 motif

Sorted Z-values of Tfcp2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfcp2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_43455919 41.33 ENSMUST00000214476.2
CD24a antigen
chr8_+_94899292 34.69 ENSMUST00000034214.8
ENSMUST00000212806.2
metallothionein 2
chr10_+_43455157 29.44 ENSMUST00000058714.10
CD24a antigen
chr17_-_48758538 24.73 ENSMUST00000024794.12
translocator protein 2
chr3_-_90603013 23.70 ENSMUST00000069960.12
ENSMUST00000117167.2
S100 calcium binding protein A9 (calgranulin B)
chr8_+_57964921 21.51 ENSMUST00000067925.8
high mobility group box 2
chr8_+_57964956 18.31 ENSMUST00000210871.2
high mobility group box 2
chr11_+_68936457 17.89 ENSMUST00000108666.8
ENSMUST00000021277.6
aurora kinase B
chr11_+_116423266 15.27 ENSMUST00000106386.8
ENSMUST00000145737.8
ENSMUST00000155102.8
ENSMUST00000063446.13
sphingosine kinase 1
chr13_-_100922910 14.11 ENSMUST00000174038.2
ENSMUST00000091295.14
ENSMUST00000072119.15
cyclin B1
chr10_+_75407356 13.33 ENSMUST00000143226.8
ENSMUST00000124259.8
gamma-glutamyltransferase 1
chr5_+_33815466 13.05 ENSMUST00000074849.13
ENSMUST00000079534.11
ENSMUST00000201633.2
transforming, acidic coiled-coil containing protein 3
chr17_+_28426752 12.90 ENSMUST00000002327.6
ENSMUST00000233560.2
ENSMUST00000233958.2
ENSMUST00000233170.2
differentially expressed in FDCP 6
chr4_-_154110324 12.34 ENSMUST00000130175.8
ENSMUST00000182151.8
small integral membrane protein 1
chr11_-_99328969 12.15 ENSMUST00000017743.3
keratin 20
chr4_-_133695204 12.06 ENSMUST00000100472.10
ENSMUST00000136327.2
high mobility group nucleosomal binding domain 2
chr4_-_154110073 11.88 ENSMUST00000182191.8
ENSMUST00000146543.9
ENSMUST00000146426.2
small integral membrane protein 1
chr11_+_23206001 11.81 ENSMUST00000020538.13
ENSMUST00000109551.8
ENSMUST00000102870.8
ENSMUST00000102869.8
exportin 1
chrX_+_72683020 11.76 ENSMUST00000019701.9
dual specificity phosphatase 9
chr4_-_154110383 11.71 ENSMUST00000132541.8
ENSMUST00000143047.8
small integral membrane protein 1
chr12_+_24758968 11.08 ENSMUST00000154588.2
ribonucleotide reductase M2
chr19_-_40576897 10.87 ENSMUST00000025979.13
aldehyde dehydrogenase 18 family, member A1
chr19_-_40576782 10.64 ENSMUST00000176939.8
aldehyde dehydrogenase 18 family, member A1
chr8_+_3715747 10.36 ENSMUST00000014118.4
mast cell expressed membrane protein 1
chr4_-_133695264 9.28 ENSMUST00000102553.11
high mobility group nucleosomal binding domain 2
chr5_+_33815910 9.09 ENSMUST00000114426.10
transforming, acidic coiled-coil containing protein 3
chr7_+_95860863 8.87 ENSMUST00000107165.8
teneurin transmembrane protein 4
chr11_+_96820091 8.55 ENSMUST00000054311.6
ENSMUST00000107636.4
proline rich 15-like
chr7_-_44983080 8.46 ENSMUST00000211743.2
ENSMUST00000042194.10
transient receptor potential cation channel, subfamily M, member 4
chr11_+_69805005 8.45 ENSMUST00000057884.6
G protein pathway suppressor 2
chr2_+_84629172 8.14 ENSMUST00000102642.9
ENSMUST00000150325.2
ubiquitin-conjugating enzyme E2L 6
chrX_-_36349055 7.84 ENSMUST00000115231.4
ribosomal protein L39
chr19_-_40576817 7.80 ENSMUST00000175932.2
ENSMUST00000176955.8
ENSMUST00000149476.3
aldehyde dehydrogenase 18 family, member A1
chrX_-_74174524 7.23 ENSMUST00000114091.8
membrane protein, palmitoylated
chr14_+_75373766 6.76 ENSMUST00000145303.8
lymphocyte cytosolic protein 1
chr5_+_107112186 6.73 ENSMUST00000117196.9
ENSMUST00000031221.12
ENSMUST00000076467.13
cell division cycle 7 (S. cerevisiae)
chr5_+_114924106 6.72 ENSMUST00000137519.2
ankyrin repeat domain 13a
chr17_+_28426831 6.67 ENSMUST00000233264.2
differentially expressed in FDCP 6
chr14_+_75373915 6.44 ENSMUST00000122840.8
lymphocyte cytosolic protein 1
chr15_+_89206923 6.41 ENSMUST00000066991.7
adrenomedullin 2
chr3_-_102871440 6.37 ENSMUST00000058899.13
nuclear receptor subfamily 1, group H, member 5
chr1_+_130659700 6.35 ENSMUST00000039323.8
expressed sequence AA986860
chr4_+_114945905 6.29 ENSMUST00000171877.8
ENSMUST00000177647.8
ENSMUST00000106548.9
ENSMUST00000030488.3
PDZK1 interacting protein 1
chr17_-_24746911 6.14 ENSMUST00000176652.8
TNF receptor-associated factor 7
chr10_+_79855454 6.12 ENSMUST00000043311.7
Rho GTPase activating protein 45
chr5_-_30278552 6.11 ENSMUST00000198095.2
ENSMUST00000196872.2
ENSMUST00000026846.11
thymidylate synthase
chr19_-_34143437 6.09 ENSMUST00000025686.9
ankyrin repeat domain 22
chr17_-_24746804 6.07 ENSMUST00000176353.8
ENSMUST00000176237.8
TNF receptor-associated factor 7
chr14_-_70945434 5.98 ENSMUST00000228346.2
exportin 7
chr8_-_111573401 5.89 ENSMUST00000042012.7
splicing factor 3b, subunit 3
chr17_+_35278011 5.78 ENSMUST00000007255.13
ENSMUST00000174493.8
dimethylarginine dimethylaminohydrolase 2
chr11_+_50267808 5.70 ENSMUST00000109142.8
heterogeneous nuclear ribonucleoprotein H1
chr9_+_50768224 5.68 ENSMUST00000174628.8
ENSMUST00000034560.14
ENSMUST00000114437.9
ENSMUST00000175645.8
ENSMUST00000176349.8
ENSMUST00000176798.8
ENSMUST00000175640.8
protein phosphatase 2, regulatory subunit A, beta
chr11_+_48691175 5.60 ENSMUST00000020640.8
receptor for activated C kinase 1
chrX_+_55824797 5.51 ENSMUST00000114773.10
four and a half LIM domains 1
chr5_-_140634773 5.46 ENSMUST00000197452.5
ENSMUST00000042661.8
tweety family member 3
chr2_-_51824937 5.26 ENSMUST00000102767.8
ENSMUST00000102768.8
RNA binding motif protein 43
chr8_+_124059414 5.19 ENSMUST00000010298.7
spire type actin nucleation factor 2
chr2_-_148285450 5.07 ENSMUST00000099269.4
CD93 antigen
chrX_+_7708034 4.95 ENSMUST00000033494.16
ENSMUST00000115666.8
OTU domain containing 5
chr7_+_141027763 4.88 ENSMUST00000106003.2
ribosomal protein, large P2
chrX_-_162859126 4.75 ENSMUST00000071667.9
siah E3 ubiquitin protein ligase 1B
chrX_-_162859095 4.75 ENSMUST00000037928.9
siah E3 ubiquitin protein ligase 1B
chr7_+_97480125 4.69 ENSMUST00000206351.2
p21 (RAC1) activated kinase 1
chr15_-_79976016 4.61 ENSMUST00000185306.3
ribosomal protein L3
chr2_+_84966569 4.56 ENSMUST00000057019.9
apelin receptor
chr18_+_11766333 4.54 ENSMUST00000115861.9
retinoblastoma binding protein 8, endonuclease
chr7_-_35096133 4.47 ENSMUST00000154597.2
ENSMUST00000032704.12
Fanconi anemia core complex associated protein 24
chr19_-_8690330 4.41 ENSMUST00000206598.2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr17_+_34812361 4.31 ENSMUST00000174532.2
pre B cell leukemia homeobox 2
chr10_+_13376745 4.30 ENSMUST00000060212.13
ENSMUST00000121465.3
fucosidase, alpha-L- 2, plasma
chr6_-_34294377 4.28 ENSMUST00000154655.2
ENSMUST00000102980.11
aldo-keto reductase family 1, member B3 (aldose reductase)
chr19_-_46917661 4.28 ENSMUST00000236727.2
5'-nucleotidase, cytosolic II
chr13_-_76166789 4.27 ENSMUST00000179078.9
ENSMUST00000167271.9
Rieske (Fe-S) domain containing
chr12_-_114252202 4.22 ENSMUST00000195124.6
ENSMUST00000103481.3
immunoglobulin heavy variable 3-6
chr3_-_92493507 4.13 ENSMUST00000194965.6
sperm mitochondria-associated cysteine-rich protein
chr6_+_5390386 3.92 ENSMUST00000183358.2
ankyrin repeat and SOCS box-containing 4
chr5_-_34794185 3.85 ENSMUST00000149657.5
major facilitator superfamily domain containing 10
chr19_-_38032006 3.85 ENSMUST00000172095.3
ENSMUST00000041475.16
myoferlin
chr8_+_121215155 3.77 ENSMUST00000034279.16
genetic suppressor element 1, coiled-coil protein
chr2_-_167852538 3.72 ENSMUST00000099073.3
RIPOR family member 3
chr6_-_116693849 3.64 ENSMUST00000056623.13
transmembrane protein 72
chr1_-_149836974 3.62 ENSMUST00000190507.2
ENSMUST00000070200.15
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr12_-_91712783 3.53 ENSMUST00000166967.2
stonin 2
chr15_-_103446354 3.51 ENSMUST00000023133.8
protein phosphatase 1, regulatory inhibitor subunit 1A
chr7_+_101619019 3.45 ENSMUST00000084852.13
nuclear mitotic apparatus protein 1
chr16_-_19079594 3.43 ENSMUST00000103752.3
ENSMUST00000197518.2
immunoglobulin lambda variable 2
chr19_-_38031774 3.33 ENSMUST00000226068.2
myoferlin
chr5_-_129864202 3.27 ENSMUST00000136507.4
phosphoserine phosphatase
chr14_+_30201569 3.13 ENSMUST00000022535.9
ENSMUST00000223658.2
decapping mRNA 1A
chr12_+_78908466 3.06 ENSMUST00000071230.8
eukaryotic translation initiation factor 2, subunit 1 alpha
chr5_-_142892457 3.04 ENSMUST00000167721.8
ENSMUST00000163829.2
ENSMUST00000100497.11
actin, beta
chr4_-_139079842 3.04 ENSMUST00000102503.10
mRNA turnover 4, ribosome maturation factor
chr9_+_123902143 3.02 ENSMUST00000168841.3
ENSMUST00000055918.7
chemokine (C-C motif) receptor 2
chr11_-_102207486 3.02 ENSMUST00000146896.9
ENSMUST00000079589.11
upstream binding transcription factor, RNA polymerase I
chr11_+_75422516 3.01 ENSMUST00000149727.8
ENSMUST00000108433.8
ENSMUST00000042561.14
ENSMUST00000143035.8
solute carrier family 43, member 2
chr3_+_58433236 2.96 ENSMUST00000029387.15
eukaryotic translation initiation factor 2A
chr8_+_70275079 2.94 ENSMUST00000164890.8
ENSMUST00000034325.6
ENSMUST00000238452.2
lysophosphatidic acid receptor 2
chrX_+_7708295 2.91 ENSMUST00000115667.10
ENSMUST00000115668.10
ENSMUST00000115665.2
OTU domain containing 5
chr8_-_61407760 2.87 ENSMUST00000110302.8
chloride channel, voltage-sensitive 3
chr5_-_134717443 2.83 ENSMUST00000015137.10
LIM-domain containing, protein kinase
chr11_-_102207516 2.81 ENSMUST00000107115.8
ENSMUST00000128016.2
upstream binding transcription factor, RNA polymerase I
chr1_-_60137263 2.80 ENSMUST00000143342.8
WD repeat domain 12
chr12_-_113700190 2.77 ENSMUST00000103452.3
ENSMUST00000192264.2
immunoglobulin heavy variable 5-9-1
chr7_+_35096470 2.73 ENSMUST00000079414.12
centrosomal protein 89
chr11_-_70860778 2.70 ENSMUST00000108530.2
ENSMUST00000035283.11
ENSMUST00000108531.8
nucleoporin 88
chr11_-_45846291 2.67 ENSMUST00000011398.13
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr8_+_34089597 2.67 ENSMUST00000009774.11
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
chr1_-_52230062 2.64 ENSMUST00000156887.8
ENSMUST00000129107.2
glutaminase
chr11_-_82719850 2.62 ENSMUST00000021036.13
ENSMUST00000074515.11
ENSMUST00000103218.3
ring finger and FYVE like domain containing protein
chr19_-_53932581 2.55 ENSMUST00000236885.2
ENSMUST00000236098.2
ENSMUST00000236370.2
BBSome interacting protein 1
chr6_-_39534765 2.47 ENSMUST00000036877.10
ENSMUST00000154149.2
DENN/MADD domain containing 2A
chr12_-_114286421 2.43 ENSMUST00000103483.3
immunoglobulin heavy variable V3-8
chr4_-_139079609 2.41 ENSMUST00000030513.13
ENSMUST00000155257.8
mRNA turnover 4, ribosome maturation factor
chr3_+_84859453 2.41 ENSMUST00000029727.8
F-box and WD-40 domain protein 7
chr11_-_8614497 2.41 ENSMUST00000020695.13
tensin 3
chr1_+_55091922 2.38 ENSMUST00000087617.11
ENSMUST00000027125.7
coenzyme Q10B
chr4_-_129334593 2.35 ENSMUST00000053042.6
ENSMUST00000106046.8
zinc finger and BTB domain containing 8b
chr16_-_3725515 2.33 ENSMUST00000177221.2
ENSMUST00000177323.8
RIKEN cDNA 1700037C18 gene
chr3_+_146156220 2.27 ENSMUST00000061937.13
ENSMUST00000029840.4
chitobiase
chr3_+_122522592 2.24 ENSMUST00000066728.10
phosphodiesterase 5A, cGMP-specific
chr19_-_45738002 2.17 ENSMUST00000070215.8
nucleoplasmin 3
chr6_-_142517340 2.14 ENSMUST00000203945.3
potassium inwardly-rectifying channel, subfamily J, member 8
chr5_+_129864044 2.06 ENSMUST00000201414.5
chaperonin containing Tcp1, subunit 6a (zeta)
chr9_-_67739607 1.98 ENSMUST00000054500.7
C2 calcium-dependent domain containing 4A
chr19_-_24178000 1.92 ENSMUST00000233658.3
tight junction protein 2
chr19_+_29344846 1.92 ENSMUST00000016640.8
CD274 antigen
chr18_+_61058684 1.91 ENSMUST00000102888.10
ENSMUST00000025519.11
calcium/calmodulin-dependent protein kinase II alpha
chr19_-_29344694 1.84 ENSMUST00000138051.2
plasminogen receptor, C-terminal lysine transmembrane protein
chr19_-_10847121 1.84 ENSMUST00000120524.2
ENSMUST00000025645.14
transmembrane protein 132A
chr3_+_123240562 1.78 ENSMUST00000029603.10
protease, serine 12 neurotrypsin (motopsin)
chr11_-_61065846 1.76 ENSMUST00000041683.9
ubiquitin specific peptidase 22
chr5_-_100648487 1.69 ENSMUST00000239512.1
lin-54 homolog (C. elegans)
chr11_-_8614667 1.61 ENSMUST00000239111.2
tensin 3
chr4_-_133329479 1.57 ENSMUST00000057311.4
stratifin
chr2_+_32460868 1.57 ENSMUST00000140592.8
ENSMUST00000028151.7
dolichol-phosphate (beta-D) mannosyltransferase 2
chr13_+_51562675 1.56 ENSMUST00000087978.5
sphingosine-1-phosphate receptor 3
chr15_-_11905697 1.53 ENSMUST00000066529.5
ENSMUST00000228603.2
natriuretic peptide receptor 3
chr16_+_43960183 1.50 ENSMUST00000159514.8
ENSMUST00000161326.8
ENSMUST00000063520.15
ENSMUST00000063542.8
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr11_-_95805710 1.46 ENSMUST00000038343.7
beta-1,4-N-acetyl-galactosaminyl transferase 2
chr14_-_54651442 1.45 ENSMUST00000227334.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr2_-_102016717 1.42 ENSMUST00000058790.12
low density lipoprotein receptor class A domain containing 3
chrX_-_20816841 1.40 ENSMUST00000009550.14
ELK1, member of ETS oncogene family
chr6_+_67838100 1.36 ENSMUST00000200586.2
ENSMUST00000103309.3
immunoglobulin kappa variable 17-127
chrX_+_151016224 1.36 ENSMUST00000112588.9
ENSMUST00000082177.13
lysine (K)-specific demethylase 5C
chr19_-_60849828 1.35 ENSMUST00000135808.8
sideroflexin 4
chr2_-_102016665 1.34 ENSMUST00000111222.2
low density lipoprotein receptor class A domain containing 3
chr7_-_7139723 1.33 ENSMUST00000211240.2
ENSMUST00000032622.9
zinc finger protein 773
chr19_+_6887059 1.31 ENSMUST00000088257.14
ENSMUST00000116551.10
tRNA methyltransferase 11-2
chr9_+_35334878 1.30 ENSMUST00000154652.8
cell adhesion molecule-related/down-regulated by oncogenes
chr4_-_132149704 1.27 ENSMUST00000152271.8
ENSMUST00000084170.12
phosphatase and actin regulator 4
chr4_+_118478357 1.26 ENSMUST00000147373.2
EBNA1 binding protein 2
chr3_-_95014090 1.23 ENSMUST00000005768.8
ENSMUST00000107232.9
ENSMUST00000107236.9
phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
chr4_+_109533753 1.22 ENSMUST00000102724.5
Fas-associated factor 1
chr15_-_78058214 1.22 ENSMUST00000016781.8
intraflagellar transport 27
chrX_+_52001108 1.20 ENSMUST00000078944.13
ENSMUST00000101587.10
ENSMUST00000154864.4
PHD finger protein 6
chr3_-_143908111 1.16 ENSMUST00000121796.8
LIM domain only 4
chr14_-_22039543 1.15 ENSMUST00000043409.9
zinc finger protein 503
chr4_-_49593875 1.08 ENSMUST00000151542.2
post-GPI attachment to proteins GalNAc transferase 4
chr9_-_65734826 1.07 ENSMUST00000159109.2
zinc finger protein 609
chr11_+_3845221 1.06 ENSMUST00000109996.8
ENSMUST00000055931.5
dual specificity phosphatase 18
chr10_+_69048506 1.05 ENSMUST00000167384.8
Rho-related BTB domain containing 1
chr10_+_79766254 1.02 ENSMUST00000131118.2
AT rich interactive domain 3A (BRIGHT-like)
chr3_+_95018324 1.01 ENSMUST00000009102.9
vacuolar protein sorting 72
chr13_+_95112852 1.00 ENSMUST00000160115.8
ENSMUST00000222995.2
ENSMUST00000160801.8
ENSMUST00000056512.14
WD repeat domain 41
chr11_-_45845992 0.99 ENSMUST00000109254.2
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr17_+_32671689 0.97 ENSMUST00000237491.2
cytochrome P450, family 4, subfamily f, polypeptide 39
chr3_-_143908060 0.93 ENSMUST00000121112.6
LIM domain only 4
chr9_+_108368032 0.90 ENSMUST00000166103.9
ENSMUST00000085044.14
ENSMUST00000193678.6
ENSMUST00000178075.8
ubiquitin specific peptidase 19
chr19_-_55229668 0.89 ENSMUST00000069183.8
guanylate cyclase 2g
chr12_-_114330574 0.87 ENSMUST00000103485.3
immunoglobulin heavy variable V12-3
chr2_+_156562956 0.87 ENSMUST00000109566.9
ENSMUST00000146412.9
ENSMUST00000177013.8
ENSMUST00000171030.9
DLG associated protein 4
chr14_-_21898992 0.84 ENSMUST00000124549.9
catechol-O-methyltransferase domain containing 1
chr13_+_119599287 0.83 ENSMUST00000026519.10
ENSMUST00000225186.2
ENSMUST00000224081.2
ENSMUST00000224312.2
RIKEN cDNA 4833420G17 gene
chr18_+_65715156 0.82 ENSMUST00000237553.2
ENSMUST00000237712.2
ENSMUST00000182684.8
zinc finger protein 532
chrX_+_163763588 0.80 ENSMUST00000167446.8
ENSMUST00000057150.8
Fanconi anemia, complementation group B
chr14_+_79718604 0.80 ENSMUST00000040131.13
E74-like factor 1
chr13_-_76166643 0.80 ENSMUST00000050997.2
Rieske (Fe-S) domain containing
chr4_-_149858694 0.80 ENSMUST00000105686.3
solute carrier family 25, member 33
chr18_+_61688378 0.79 ENSMUST00000165721.8
ENSMUST00000115246.9
ENSMUST00000166990.8
ENSMUST00000163205.8
ENSMUST00000170862.8
casein kinase 1, alpha 1
chr3_-_95014218 0.76 ENSMUST00000107233.9
phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
chr18_+_37880027 0.75 ENSMUST00000193404.2
protocadherin gamma subfamily A, 10
chr11_+_103857541 0.71 ENSMUST00000057921.10
ENSMUST00000063347.12
ADP-ribosylation factor 2
chr3_+_138233004 0.71 ENSMUST00000196990.5
ENSMUST00000200239.5
ENSMUST00000200100.2
eukaryotic translation initiation factor 4E
chr19_-_8906686 0.70 ENSMUST00000096242.5
rod outer segment membrane protein 1
chr18_+_37869950 0.68 ENSMUST00000091935.7
protocadherin gamma subfamily A, 9
chr10_-_129962924 0.66 ENSMUST00000074161.2
olfactory receptor 824
chr12_-_70160491 0.62 ENSMUST00000222237.2
ninein
chr4_-_116024788 0.58 ENSMUST00000030465.10
ENSMUST00000143426.2
tetraspanin 1
chr11_+_4852212 0.54 ENSMUST00000142543.3
THO complex 5
chr2_+_16361582 0.52 ENSMUST00000114703.10
plexin domain containing 2
chr9_+_15150341 0.45 ENSMUST00000034413.8
V-set and transmembrane domain containing 5
chr17_+_37148015 0.45 ENSMUST00000179968.8
ENSMUST00000130367.8
ENSMUST00000053434.15
ENSMUST00000130801.8
ENSMUST00000144182.8
ENSMUST00000123715.8
tripartite motif-containing 26
chr2_-_132420047 0.43 ENSMUST00000028822.14
glycerophosphocholine phosphodiesterase 1
chr14_-_45096827 0.43 ENSMUST00000095959.2
prostaglandin D receptor
chr16_-_32630847 0.43 ENSMUST00000179384.3
somatomedin B domain containing 1
chr3_-_41696906 0.42 ENSMUST00000026866.15
sodium channel and clathrin linker 1
chr10_-_127587576 0.42 ENSMUST00000079692.6
G protein-coupled receptor 182
chr16_+_20492267 0.42 ENSMUST00000115460.8
eukaryotic translation initiation factor 4, gamma 1
chr3_+_90201388 0.42 ENSMUST00000199607.5
GATA zinc finger domain containing 2B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
23.6 70.8 GO:0034117 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
9.8 29.3 GO:0006592 ornithine biosynthetic process(GO:0006592)
7.9 23.7 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
6.0 17.9 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
4.3 34.7 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
4.0 39.8 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
3.5 14.1 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
2.8 8.5 GO:1903116 positive regulation of actin filament-based movement(GO:1903116)
2.2 8.9 GO:0060912 cardiac cell fate specification(GO:0060912)
2.2 15.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
2.0 7.9 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
1.7 5.1 GO:0042128 nitrate assimilation(GO:0042128)
1.7 13.3 GO:1901748 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
1.5 4.6 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
1.5 14.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.4 4.3 GO:0090420 hexitol metabolic process(GO:0006059) naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
1.4 5.6 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
1.3 5.2 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
1.2 6.1 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
1.2 4.7 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
1.1 6.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
1.1 25.6 GO:0030953 astral microtubule organization(GO:0030953)
1.0 8.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
1.0 3.9 GO:0015904 tetracycline transport(GO:0015904)
1.0 2.9 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.9 2.8 GO:1902567 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.9 4.4 GO:0060356 leucine import(GO:0060356)
0.9 12.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.7 3.6 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.7 2.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.7 2.6 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.6 19.3 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.6 13.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.6 3.0 GO:1990928 response to amino acid starvation(GO:1990928)
0.6 4.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.6 5.8 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.5 9.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.5 1.6 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.5 7.8 GO:0002227 innate immune response in mucosa(GO:0002227)
0.5 3.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.5 4.5 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.5 2.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.5 4.3 GO:0006004 fucose metabolic process(GO:0006004)
0.5 10.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.4 5.8 GO:0006527 arginine catabolic process(GO:0006527)
0.4 2.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.4 1.3 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.4 3.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.4 7.2 GO:0001778 plasma membrane repair(GO:0001778)
0.4 12.2 GO:0045109 intermediate filament organization(GO:0045109)
0.4 2.2 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678) positive regulation of oocyte development(GO:0060282)
0.3 3.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.3 3.9 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 2.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.3 2.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3 1.9 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.3 10.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 0.8 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.3 4.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 1.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 1.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.2 1.2 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.2 1.6 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 1.9 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 2.1 GO:1990573 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915) potassium ion import across plasma membrane(GO:1990573)
0.2 1.8 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 1.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.2 0.7 GO:0061386 closure of optic fissure(GO:0061386)
0.2 7.2 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.2 4.5 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.2 1.5 GO:0002158 osteoclast proliferation(GO:0002158)
0.2 0.8 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.2 0.6 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.2 1.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 2.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 1.9 GO:0098970 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 1.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 8.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 2.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 2.1 GO:1903405 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 5.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 1.5 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 2.8 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.1 1.6 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 2.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.4 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 4.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 4.9 GO:0006414 translational elongation(GO:0006414)
0.1 0.5 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 6.0 GO:0006611 protein export from nucleus(GO:0006611)
0.1 1.8 GO:0016578 histone deubiquitination(GO:0016578)
0.1 5.7 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.1 2.2 GO:0009303 rRNA transcription(GO:0009303)
0.1 8.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 2.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.3 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.1 0.3 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 1.0 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 3.7 GO:0006400 tRNA modification(GO:0006400)
0.0 2.7 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 1.4 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.0 GO:0043486 histone exchange(GO:0043486)
0.0 2.0 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.2 GO:0060058 bile acid signaling pathway(GO:0038183) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 2.6 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 5.9 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 1.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.7 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.3 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.6 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.7 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.8 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 1.2 GO:0090102 cochlea development(GO:0090102)
0.0 0.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.9 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.4 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 3.7 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 1.9 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 1.2 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.0 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.4 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 14.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
3.0 17.9 GO:0032133 chromosome passenger complex(GO:0032133)
2.6 70.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.9 5.6 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
1.6 9.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.0 3.1 GO:0043614 multi-eIF complex(GO:0043614)
0.9 11.8 GO:0005642 annulate lamellae(GO:0005642)
0.9 4.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.7 3.5 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.6 1.9 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.6 2.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.6 3.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4 3.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.4 13.2 GO:0001891 phagocytic cup(GO:0001891)
0.4 1.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 2.8 GO:0070545 PeBoW complex(GO:0070545)
0.3 5.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.3 8.5 GO:0034706 sodium channel complex(GO:0034706)
0.2 2.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 17.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 6.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 3.8 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 2.6 GO:0034464 BBSome(GO:0034464)
0.2 4.7 GO:0071437 invadopodium(GO:0071437)
0.2 1.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 1.5 GO:0031415 NatA complex(GO:0031415)
0.1 36.4 GO:0000793 condensed chromosome(GO:0000793)
0.1 2.9 GO:0042581 specific granule(GO:0042581)
0.1 2.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 2.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 3.8 GO:0042588 zymogen granule(GO:0042588)
0.1 1.8 GO:0000124 SAGA complex(GO:0000124)
0.1 6.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.8 GO:0043083 synaptic cleft(GO:0043083)
0.1 8.7 GO:0005643 nuclear pore(GO:0005643)
0.1 0.9 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 11.3 GO:0005882 intermediate filament(GO:0005882)
0.1 12.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 5.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 1.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 2.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.3 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.5 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 8.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 2.1 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.9 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0000235 astral microtubule(GO:0000235)
0.0 0.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 2.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 7.3 GO:0005901 caveola(GO:0005901)
0.0 5.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 22.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 19.9 GO:0005813 centrosome(GO:0005813)
0.0 5.3 GO:0001650 fibrillar center(GO:0001650)
0.0 2.6 GO:0031526 brush border membrane(GO:0031526)
0.0 10.7 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 3.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 4.5 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 3.3 GO:0030139 endocytic vesicle(GO:0030139)
0.0 3.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 15.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.2 GO:0000776 kinetochore(GO:0000776)
0.0 3.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.0 GO:0005815 microtubule organizing center(GO:0005815)
0.0 4.0 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 5.7 GO:0005925 focal adhesion(GO:0005925)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.3 GO:0004350 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
6.4 63.5 GO:0050786 RAGE receptor binding(GO:0050786)
3.1 70.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
2.4 14.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.7 15.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
1.6 9.9 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.4 4.3 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
1.4 17.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
1.4 8.1 GO:0042296 ISG15 transferase activity(GO:0042296)
1.2 3.7 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
1.1 13.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
1.0 5.1 GO:0098809 nitrite reductase activity(GO:0098809)
1.0 7.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
1.0 5.8 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
1.0 3.9 GO:0008493 tetracycline transporter activity(GO:0008493)
0.9 2.8 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.9 17.9 GO:0035174 histone serine kinase activity(GO:0035174)
0.7 2.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.7 11.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.7 5.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.7 2.1 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.6 5.1 GO:0001849 complement component C1q binding(GO:0001849)
0.5 3.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.5 5.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.5 4.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.5 6.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.4 2.6 GO:0004359 glutaminase activity(GO:0004359)
0.4 2.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.4 3.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.4 2.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.4 1.6 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 2.4 GO:0048039 ubiquinone binding(GO:0048039)
0.3 4.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.3 24.7 GO:0015485 cholesterol binding(GO:0015485)
0.3 4.6 GO:0008097 5S rRNA binding(GO:0008097)
0.3 1.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.3 1.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 2.3 GO:0004568 chitinase activity(GO:0004568)
0.2 2.1 GO:0017098 sulfonylurea receptor binding(GO:0017098) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 0.7 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
0.2 2.0 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 4.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 3.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 5.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 6.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.2 1.4 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 1.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.0 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 7.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 3.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.7 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 2.2 GO:0030553 cGMP binding(GO:0030553)
0.1 0.2 GO:1902121 lithocholic acid binding(GO:1902121)
0.1 6.0 GO:0043022 ribosome binding(GO:0043022)
0.1 12.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 8.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 3.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 4.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.4 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 1.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 11.5 GO:0051015 actin filament binding(GO:0051015)
0.0 3.1 GO:0019894 kinesin binding(GO:0019894)
0.0 2.6 GO:0002039 p53 binding(GO:0002039)
0.0 1.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 4.6 GO:0005179 hormone activity(GO:0005179)
0.0 2.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.8 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 28.2 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 4.3 GO:0044325 ion channel binding(GO:0044325)
0.0 2.2 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.7 GO:0097110 scaffold protein binding(GO:0097110)
0.0 16.1 GO:0019904 protein domain specific binding(GO:0019904)
0.0 3.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0017069 snRNA binding(GO:0017069)
0.0 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 44.7 PID AURORA A PATHWAY Aurora A signaling
0.6 11.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.5 16.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.3 12.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 14.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 21.7 PID E2F PATHWAY E2F transcription factor network
0.2 19.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 12.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 2.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 2.4 PID MYC PATHWAY C-MYC pathway
0.1 3.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 6.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 7.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 7.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.8 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 3.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.1 PID SHP2 PATHWAY SHP2 signaling
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 39.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.1 14.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
1.0 11.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.8 21.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.7 20.2 REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION Genes involved in E2F mediated regulation of DNA replication
0.4 19.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.4 5.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 2.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.3 6.2 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.3 16.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3 4.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.3 4.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 13.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 3.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 17.9 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.2 3.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 3.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 4.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 17.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 3.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 5.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 2.8 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 5.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.9 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 2.1 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 1.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 0.7 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1 2.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 5.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 5.2 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 2.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 8.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions