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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Tlx1

Z-value: 2.49

Motif logo

Transcription factors associated with Tlx1

Gene Symbol Gene ID Gene Info
ENSMUSG00000025215.11 Tlx1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tlx1mm39_v1_chr19_+_45139908_45140034-0.144.3e-01Click!

Activity profile of Tlx1 motif

Sorted Z-values of Tlx1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tlx1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_55152002 28.07 ENSMUST00000003569.6
indolethylamine N-methyltransferase
chr9_-_57590926 21.48 ENSMUST00000034860.5
cytochrome P450, family 1, subfamily a, polypeptide 2
chr7_+_119125426 19.43 ENSMUST00000066465.3
acyl-CoA synthetase medium-chain family member 5
chr7_+_119125546 19.35 ENSMUST00000207387.2
ENSMUST00000207813.2
acyl-CoA synthetase medium-chain family member 5
chr7_+_119125443 18.83 ENSMUST00000207440.2
acyl-CoA synthetase medium-chain family member 5
chr7_+_26534730 16.95 ENSMUST00000005685.15
cytochrome P450, family 2, subfamily a, polypeptide 5
chr7_-_97066937 15.03 ENSMUST00000043077.8
thyroid hormone responsive
chr17_-_56428968 10.56 ENSMUST00000041357.9
leucine-rich alpha-2-glycoprotein 1
chr10_-_39901249 9.76 ENSMUST00000163705.3
major facilitator superfamily domain containing 4B1
chr14_+_66208253 9.23 ENSMUST00000138191.8
clusterin
chr10_+_128089965 9.19 ENSMUST00000060782.5
ENSMUST00000218722.2
apolipoprotein N
chr10_-_81127057 8.49 ENSMUST00000045744.7
tight junction protein 3
chr14_+_66208059 8.35 ENSMUST00000127387.8
clusterin
chr14_+_51328534 7.97 ENSMUST00000022428.13
ENSMUST00000171688.9
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr14_+_66208498 7.89 ENSMUST00000128539.8
clusterin
chr11_+_115353290 7.73 ENSMUST00000106532.4
ENSMUST00000092445.12
ENSMUST00000153466.2
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr19_+_32597379 7.71 ENSMUST00000236290.2
ENSMUST00000025833.7
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr14_+_66208613 7.58 ENSMUST00000144619.2
clusterin
chr7_+_26006594 7.39 ENSMUST00000098657.5
cytochrome P450, family 2, subfamily a, polypeptide 4
chr5_+_146016064 7.12 ENSMUST00000035571.10
cytochrome P450, family 3, subfamily a, polypeptide 59
chr13_-_42001075 6.87 ENSMUST00000179758.8
androgen dependent TFPI regulating protein
chr7_-_12732067 6.70 ENSMUST00000032539.14
ENSMUST00000120903.8
solute carrier family 27 (fatty acid transporter), member 5
chr13_-_42000958 6.42 ENSMUST00000072012.10
androgen dependent TFPI regulating protein
chr13_-_42001102 6.21 ENSMUST00000121404.8
androgen dependent TFPI regulating protein
chr9_+_77824646 6.02 ENSMUST00000034904.14
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr16_-_18245352 5.75 ENSMUST00000000335.12
catechol-O-methyltransferase
chr2_+_118998235 5.62 ENSMUST00000057454.4
GTP cyclohydrolase I feedback regulator
chr7_-_12731594 5.51 ENSMUST00000133977.3
solute carrier family 27 (fatty acid transporter), member 5
chr17_+_32904629 5.34 ENSMUST00000008801.7
cytochrome P450, family 4, subfamily f, polypeptide 15
chr17_+_32904601 5.28 ENSMUST00000168171.8
cytochrome P450, family 4, subfamily f, polypeptide 15
chr5_-_77262968 5.27 ENSMUST00000081964.7
HOP homeobox
chr19_-_46661501 5.21 ENSMUST00000236174.2
cytochrome P450, family 17, subfamily a, polypeptide 1
chr19_-_46661321 5.18 ENSMUST00000026012.8
cytochrome P450, family 17, subfamily a, polypeptide 1
chr4_-_57916283 4.76 ENSMUST00000063816.6
RIKEN cDNA D630039A03 gene
chr3_-_63872189 4.61 ENSMUST00000029402.15
solute carrier family 33 (acetyl-CoA transporter), member 1
chr1_-_162687254 4.54 ENSMUST00000131058.8
flavin containing monooxygenase 1
chr1_-_162687369 4.53 ENSMUST00000193078.6
flavin containing monooxygenase 1
chr11_-_75313412 4.50 ENSMUST00000138661.8
ENSMUST00000000769.14
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr11_-_75313350 4.42 ENSMUST00000125982.2
ENSMUST00000137103.8
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr7_-_126275529 4.24 ENSMUST00000106372.11
ENSMUST00000155419.3
ENSMUST00000106373.9
sulfotransferase family 1A, phenol-preferring, member 1
chr2_-_91025441 4.13 ENSMUST00000002177.9
nuclear receptor subfamily 1, group H, member 3
chr5_+_115061293 4.06 ENSMUST00000031540.11
ENSMUST00000112143.4
2'-5' oligoadenylate synthetase-like 1
chr17_-_32639936 4.06 ENSMUST00000170392.9
ENSMUST00000237165.2
ENSMUST00000235892.2
ENSMUST00000114455.3
peptidoglycan recognition protein 2
chr3_+_123061094 4.02 ENSMUST00000047923.12
ENSMUST00000200333.2
Sec24 related gene family, member D (S. cerevisiae)
chr10_-_76949762 4.01 ENSMUST00000072755.12
collagen, type XVIII, alpha 1
chr13_+_12580743 3.98 ENSMUST00000221560.2
ENSMUST00000071973.8
endoplasmic reticulum oxidoreductase 1 beta
chr10_-_76949510 3.96 ENSMUST00000105409.8
collagen, type XVIII, alpha 1
chr2_+_26969384 3.83 ENSMUST00000091233.7
ADAMTS-like 2
chr3_-_63872079 3.79 ENSMUST00000161659.8
solute carrier family 33 (acetyl-CoA transporter), member 1
chr1_+_133173826 3.58 ENSMUST00000105082.9
ENSMUST00000038295.15
pleckstrin homology domain containing, family A member 6
chr3_+_57643477 3.46 ENSMUST00000041826.14
ENSMUST00000198510.5
ENSMUST00000200497.5
ENSMUST00000198214.5
ENSMUST00000200600.5
ENSMUST00000198249.5
ENSMUST00000199041.2
ring finger protein 13
chr15_-_82291372 3.34 ENSMUST00000230198.2
ENSMUST00000230248.2
ENSMUST00000072776.5
ENSMUST00000229911.2
cytochrome P450, family 2, subfamily d, polypeptide 10
chr4_-_129121676 3.28 ENSMUST00000106051.8
expressed sequence C77080
chr3_-_88162012 3.21 ENSMUST00000171887.4
Rhesus blood group-associated B glycoprotein
chr4_-_138095277 3.19 ENSMUST00000030535.4
cytidine deaminase
chr2_-_91025208 3.16 ENSMUST00000111355.8
nuclear receptor subfamily 1, group H, member 3
chr4_+_139350152 3.16 ENSMUST00000039818.10
aldehyde dehydrogenase 4 family, member A1
chr11_+_96920956 3.13 ENSMUST00000153482.2
secernin 2
chr2_-_91025380 3.04 ENSMUST00000111356.8
nuclear receptor subfamily 1, group H, member 3
chr11_+_96920751 3.02 ENSMUST00000021249.11
secernin 2
chr3_-_107838895 3.02 ENSMUST00000133947.9
ENSMUST00000124215.2
ENSMUST00000106688.8
ENSMUST00000106687.9
glutathione S-transferase, mu 7
chr9_+_106325860 2.90 ENSMUST00000185527.3
abhydrolase domain containing 14b
chr9_+_106324952 2.87 ENSMUST00000215475.2
ENSMUST00000187106.7
ENSMUST00000190167.7
abhydrolase domain containing 14b
chr2_-_130506484 2.81 ENSMUST00000089559.11
DDRGK domain containing 1
chr10_-_127457001 2.76 ENSMUST00000049149.15
low density lipoprotein receptor-related protein 1
chr15_+_81686622 2.75 ENSMUST00000109553.10
thyrotroph embryonic factor
chr2_-_91025492 2.69 ENSMUST00000111354.2
nuclear receptor subfamily 1, group H, member 3
chr3_+_81904229 2.66 ENSMUST00000029641.10
acid-sensing (proton-gated) ion channel family member 5
chr19_-_3962733 2.66 ENSMUST00000075092.8
ENSMUST00000235847.2
ENSMUST00000235301.2
ENSMUST00000237341.2
NADH:ubiquinone oxidoreductase core subunit S8
chr9_-_106315518 2.65 ENSMUST00000024031.13
ENSMUST00000190972.3
aminoacylase 1
chr17_-_24428351 2.61 ENSMUST00000024931.6
netrin 3
chr7_-_80053063 2.60 ENSMUST00000147150.2
furin (paired basic amino acid cleaving enzyme)
chr6_-_115228800 2.57 ENSMUST00000205131.2
tissue inhibitor of metalloproteinase 4
chr11_-_77784922 2.51 ENSMUST00000017597.5
pipecolic acid oxidase
chr14_+_29730931 2.47 ENSMUST00000067620.12
choline dehydrogenase
chr8_-_96161414 2.44 ENSMUST00000211908.2
cilia and flagella associated protein 20
chr13_+_12580772 2.42 ENSMUST00000220811.2
endoplasmic reticulum oxidoreductase 1 beta
chr10_-_89369432 2.40 ENSMUST00000105297.2
nuclear receptor subfamily 1, group H, member 4
chr3_-_107839133 2.39 ENSMUST00000004137.11
glutathione S-transferase, mu 7
chr6_-_33037107 2.36 ENSMUST00000115091.2
ENSMUST00000127666.8
coiled-coil-helix-coiled-coil-helix domain containing 3
chr10_-_127456791 2.36 ENSMUST00000118455.2
ENSMUST00000121829.8
low density lipoprotein receptor-related protein 1
chr1_+_87501721 2.33 ENSMUST00000166259.8
ENSMUST00000172222.8
ENSMUST00000163606.8
neuraminidase 2
chr6_-_33037191 2.32 ENSMUST00000066379.11
coiled-coil-helix-coiled-coil-helix domain containing 3
chr11_+_109376432 2.30 ENSMUST00000106697.8
arylsulfatase G
chr3_-_85653573 2.25 ENSMUST00000118408.8
family with sequence similarity 160, member A1
chr6_+_48570817 2.24 ENSMUST00000154010.8
ENSMUST00000009420.15
ENSMUST00000163452.7
ENSMUST00000118229.2
ENSMUST00000135151.3
replication initiator 1
chr16_+_4501934 2.20 ENSMUST00000060067.12
ENSMUST00000115854.4
ENSMUST00000229529.2
DnaJ heat shock protein family (Hsp40) member A3
chrX_+_72271878 2.19 ENSMUST00000105111.4
factor 8-associated gene A
chr15_-_74869684 2.16 ENSMUST00000190188.2
ENSMUST00000189068.7
ENSMUST00000186526.7
ENSMUST00000187171.2
ENSMUST00000187994.7
lymphocyte antigen 6 complex, locus A
chr12_+_95658987 2.10 ENSMUST00000057324.4
fibronectin leucine rich transmembrane protein 2
chr6_+_55428963 2.08 ENSMUST00000070736.12
ENSMUST00000070756.12
ENSMUST00000166962.8
adenylate cyclase activating polypeptide 1 receptor 1
chr4_-_115504907 2.00 ENSMUST00000102707.10
cytochrome P450, family 4, subfamily b, polypeptide 1
chrX_-_71699740 1.93 ENSMUST00000055966.13
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr7_-_127490139 1.88 ENSMUST00000205300.2
ENSMUST00000121394.3
protease, serine 53
chr4_-_103072343 1.87 ENSMUST00000150285.8
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr6_-_115229128 1.86 ENSMUST00000032462.9
tissue inhibitor of metalloproteinase 4
chr9_-_20887967 1.83 ENSMUST00000214218.2
sphingosine-1-phosphate receptor 2
chr11_+_28803188 1.82 ENSMUST00000020759.12
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr11_+_4833186 1.78 ENSMUST00000139737.2
nipsnap homolog 1
chr10_+_60925130 1.76 ENSMUST00000020298.8
pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1
chr5_+_124621521 1.75 ENSMUST00000111453.2
small nuclear ribonucleoprotein 35 (U11/U12)
chr14_-_63415235 1.72 ENSMUST00000054963.10
farnesyl diphosphate farnesyl transferase 1
chr14_+_14296748 1.71 ENSMUST00000022268.10
pyruvate dehydrogenase (lipoamide) beta
chr17_-_12726591 1.70 ENSMUST00000024595.4
solute carrier family 22 (organic cation transporter), member 3
chr4_+_59581617 1.67 ENSMUST00000107528.8
hydroxysteroid dehydrogenase like 2
chr1_+_176642226 1.66 ENSMUST00000056773.15
ENSMUST00000027785.15
serologically defined colon cancer antigen 8
chr10_+_60925108 1.66 ENSMUST00000218005.2
pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1
chrX_+_93278526 1.64 ENSMUST00000113908.8
ENSMUST00000113916.10
kelch-like 15
chr1_+_167177545 1.58 ENSMUST00000028004.11
aldehyde dehydrogenase 9, subfamily A1
chr4_+_59581557 1.56 ENSMUST00000030078.12
hydroxysteroid dehydrogenase like 2
chr2_-_26012751 1.53 ENSMUST00000140993.2
ENSMUST00000028300.6
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr6_+_17306414 1.52 ENSMUST00000150901.2
caveolin 1, caveolae protein
chr17_+_6157154 1.50 ENSMUST00000149756.8
tubby like protein 4
chr11_-_120604551 1.50 ENSMUST00000106154.8
ENSMUST00000106155.4
ENSMUST00000055424.13
ENSMUST00000026137.8
centromere protein X
chrX_+_93278588 1.49 ENSMUST00000096369.10
ENSMUST00000113911.9
kelch-like 15
chr13_-_74642055 1.48 ENSMUST00000202645.4
ENSMUST00000221173.2
zinc finger protein 825
chr2_+_164674782 1.48 ENSMUST00000103093.10
cathepsin A
chr1_-_87501548 1.47 ENSMUST00000068681.12
neuronal guanine nucleotide exchange factor
chr5_+_34706936 1.44 ENSMUST00000179943.3
SH3-domain binding protein 2
chr2_+_81883566 1.41 ENSMUST00000047527.8
zinc finger protein 804A
chr5_-_139805661 1.41 ENSMUST00000147328.2
transmembrane protein 184a
chr2_+_90677499 1.41 ENSMUST00000136872.8
ENSMUST00000150232.8
ENSMUST00000111467.4
mitochondrial carrier 2
chr6_-_52185674 1.40 ENSMUST00000062829.9
homeobox A6
chr8_-_96161466 1.39 ENSMUST00000213086.2
ENSMUST00000034249.8
cilia and flagella associated protein 20
chr9_+_44684450 1.39 ENSMUST00000238800.2
ENSMUST00000147559.8
intraflagellar transport 46
chr11_+_115656246 1.39 ENSMUST00000093912.11
ENSMUST00000136720.8
ENSMUST00000103034.10
ENSMUST00000141871.8
transmembrane protein 94
chr2_+_164674801 1.39 ENSMUST00000103092.9
ENSMUST00000151493.3
ENSMUST00000127650.8
cathepsin A
chr9_-_124075271 1.39 ENSMUST00000071300.13
ENSMUST00000185949.2
ENSMUST00000177714.8
RIKEN cDNA 2010315B03 gene
chr8_+_12623016 1.37 ENSMUST00000210276.2
ENSMUST00000010579.8
ENSMUST00000209428.2
sperm acrosome associated 7
chr2_+_84880776 1.36 ENSMUST00000111605.9
tankyrase 1 binding protein 1
chr5_-_38649291 1.35 ENSMUST00000129099.8
solute carrier family 2 (facilitated glucose transporter), member 9
chr1_+_172309337 1.34 ENSMUST00000127052.8
immunoglobulin superfamily, member 9
chrX_-_7440480 1.34 ENSMUST00000115742.9
ENSMUST00000150787.8
protein phosphatase 1, regulatory subunit 3F
chr2_-_71377088 1.33 ENSMUST00000024159.8
distal-less homeobox 2
chr5_+_150119860 1.33 ENSMUST00000202600.4
FRY microtubule binding protein
chr8_-_70805861 1.31 ENSMUST00000215817.2
ENSMUST00000075666.8
UPF1 regulator of nonsense transcripts homolog (yeast)
chr3_+_102927901 1.28 ENSMUST00000198180.5
ENSMUST00000197827.5
ENSMUST00000199240.5
ENSMUST00000199420.5
ENSMUST00000199571.5
ENSMUST00000197488.5
cold shock domain containing E1, RNA binding
chr5_+_34706911 1.22 ENSMUST00000118545.8
SH3-domain binding protein 2
chr2_-_155661324 1.22 ENSMUST00000124586.2
cDNA sequence BC029722
chr9_+_44684324 1.20 ENSMUST00000214854.3
ENSMUST00000125877.8
intraflagellar transport 46
chr18_+_13139992 1.19 ENSMUST00000041676.3
ENSMUST00000234084.2
ENSMUST00000234565.2
histamine receptor H4
chr7_+_141047416 1.14 ENSMUST00000209988.2
CD151 antigen
chr1_-_37904135 1.13 ENSMUST00000155852.7
ENSMUST00000193669.2
ENSMUST00000041815.15
testis specific 10
chrX_-_47763355 1.11 ENSMUST00000053970.4
G-protein coupled receptor 119
chr1_+_162398084 1.11 ENSMUST00000132158.8
ENSMUST00000135241.8
vesicle-associated membrane protein 4
chr7_+_141047298 1.11 ENSMUST00000106000.10
ENSMUST00000209892.2
ENSMUST00000177840.9
CD151 antigen
chr6_-_73198608 1.09 ENSMUST00000064948.13
ENSMUST00000114040.8
dynein, axonemal, heavy chain 6
chr2_-_144173615 1.07 ENSMUST00000103171.10
ovo like zinc finger 2
chr9_+_65172455 1.07 ENSMUST00000048762.8
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr7_+_40547608 1.06 ENSMUST00000044705.12
V-set and transmembrane domain containing 2B
chr13_-_98951627 1.05 ENSMUST00000224992.2
ENSMUST00000225840.2
FCH domain only 2
chr3_-_104419128 1.03 ENSMUST00000199070.5
ENSMUST00000046316.11
ENSMUST00000198332.2
leucine-rich repeats and immunoglobulin-like domains 2
chr13_+_43938251 1.02 ENSMUST00000015540.4
CD83 antigen
chr6_-_138635447 1.02 ENSMUST00000054786.6
immunoglobulin (CD79A) binding protein 1b
chr18_-_33596468 1.02 ENSMUST00000171533.9
neuronal regeneration related protein
chr4_+_48045143 1.01 ENSMUST00000030025.10
nuclear receptor subfamily 4, group A, member 3
chr1_-_172034251 1.00 ENSMUST00000155109.2
phosphoprotein enriched in astrocytes 15A
chr7_+_123061535 1.00 ENSMUST00000098056.6
aquaporin 8
chr18_+_70605722 0.99 ENSMUST00000174118.8
StAR-related lipid transfer (START) domain containing 6
chr19_-_11796085 0.97 ENSMUST00000211047.2
ENSMUST00000075304.14
ENSMUST00000211641.2
syntaxin 3
chr1_-_162687488 0.97 ENSMUST00000134098.8
ENSMUST00000111518.3
flavin containing monooxygenase 1
chr16_-_48814294 0.96 ENSMUST00000114516.8
DAZ interacting protein 3, zinc finger
chr1_-_132953068 0.96 ENSMUST00000186617.7
ENSMUST00000067429.10
ENSMUST00000067398.13
ENSMUST00000188090.7
transformed mouse 3T3 cell double minute 4
chr6_+_17306379 0.96 ENSMUST00000115455.3
caveolin 1, caveolae protein
chr8_+_84874881 0.95 ENSMUST00000093375.5
break repair meiotic recombinase recruitment factor 1
chr11_+_97689819 0.95 ENSMUST00000143571.2
LIM and SH3 protein 1
chr18_+_70605691 0.95 ENSMUST00000164223.8
StAR-related lipid transfer (START) domain containing 6
chr16_-_48814437 0.95 ENSMUST00000121869.8
DAZ interacting protein 3, zinc finger
chr7_+_123061497 0.92 ENSMUST00000033023.10
aquaporin 8
chr15_+_74828272 0.91 ENSMUST00000188042.2
lymphocyte antigen 6 complex, locus E
chr3_+_106943472 0.90 ENSMUST00000052718.5
potassium voltage-gated channel, shaker-related subfamily, member 3
chr1_+_139349912 0.90 ENSMUST00000200243.5
ENSMUST00000039867.10
zinc finger and BTB domain containing 41
chr2_+_32518402 0.90 ENSMUST00000156578.8
adenylate kinase 1
chr17_+_34149820 0.90 ENSMUST00000234226.2
ral guanine nucleotide dissociation stimulator-like 2
chr6_+_55429162 0.90 ENSMUST00000167484.2
adenylate cyclase activating polypeptide 1 receptor 1
chr3_+_99792699 0.89 ENSMUST00000164539.2
sperm associated antigen 17
chr19_-_42740898 0.87 ENSMUST00000237747.2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr10_-_80374941 0.87 ENSMUST00000020383.6
ATPase, class I, type 8B, member 3
chr11_-_8989582 0.87 ENSMUST00000043377.6
Sad1 and UNC84 domain containing 3
chr3_-_6685492 0.87 ENSMUST00000091364.4
RIKEN cDNA 1700008P02 gene
chr19_+_5497575 0.87 ENSMUST00000025850.7
ENSMUST00000236774.2
fos-like antigen 1
chr10_-_33972503 0.86 ENSMUST00000069125.8
calcium homeostasis modulator family member 5
chr17_-_27947863 0.84 ENSMUST00000167489.2
ENSMUST00000138970.3
ENSMUST00000025054.10
ENSMUST00000114870.9
SAM pointed domain containing ets transcription factor
chr7_+_27829229 0.84 ENSMUST00000150948.2
RIKEN cDNA 9530053A07 gene
chr18_-_33597060 0.83 ENSMUST00000168890.2
neuronal regeneration related protein
chr5_-_135378729 0.82 ENSMUST00000201784.4
ENSMUST00000201791.4
FK506 binding protein 6
chr19_-_61129211 0.80 ENSMUST00000143264.8
ENSMUST00000205854.2
zinc finger protein 950
chr11_+_98337655 0.80 ENSMUST00000019456.5
growth factor receptor bound protein 7
chr18_-_64688271 0.79 ENSMUST00000235459.2
ATPase, class I, type 8B, member 1
chr7_+_43959637 0.79 ENSMUST00000107938.8
SH3 and multiple ankyrin repeat domains 1
chr8_-_68270936 0.78 ENSMUST00000120071.8
pleckstrin and Sec7 domain containing 3
chr17_+_9207165 0.78 ENSMUST00000024650.12
RIKEN cDNA 1700010I14 gene
chr17_+_31514780 0.77 ENSMUST00000237460.2
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr1_-_182110303 0.77 ENSMUST00000035295.6
delta(4)-desaturase, sphingolipid 1
chr8_-_69848167 0.75 ENSMUST00000072427.7
ENSMUST00000213012.2
ENSMUST00000239456.2
predicted gene 10033
chr18_+_90597896 0.75 ENSMUST00000211710.2
ENSMUST00000209969.3
predicted gene 45871
chr11_+_116547932 0.75 ENSMUST00000116318.3
photoreceptor disc component
chr16_+_87151073 0.74 ENSMUST00000054442.11
ENSMUST00000118310.8
ENSMUST00000120284.8
ENSMUST00000118115.2
N-6 adenine-specific DNA methyltransferase 1 (putative)
chr13_+_83672389 0.74 ENSMUST00000200394.5
myocyte enhancer factor 2C
chr6_+_83055581 0.72 ENSMUST00000177177.8
ENSMUST00000176089.2
polycomb group ring finger 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 33.1 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
5.4 21.5 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
3.3 13.0 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
2.9 11.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
1.9 7.7 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
1.4 5.8 GO:0045963 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
1.3 8.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651) positive regulation of phospholipase A2 activity(GO:0032430)
1.3 5.1 GO:0032429 regulation of phospholipase A2 activity(GO:0032429) positive regulation of lysosomal protein catabolic process(GO:1905167)
1.1 3.2 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.1 3.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
1.0 2.9 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.8 2.5 GO:0006553 lysine metabolic process(GO:0006553)
0.8 3.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.8 2.4 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.7 8.9 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.7 24.3 GO:0019373 epoxygenase P450 pathway(GO:0019373) response to stilbenoid(GO:0035634)
0.7 4.1 GO:0032824 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.7 5.4 GO:0043651 linoleic acid metabolic process(GO:0043651) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.7 2.0 GO:0018879 biphenyl metabolic process(GO:0018879)
0.6 10.4 GO:0042448 progesterone metabolic process(GO:0042448)
0.6 2.6 GO:0090472 dibasic protein processing(GO:0090472)
0.6 3.8 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.6 14.3 GO:0017144 drug metabolic process(GO:0017144)
0.6 1.7 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.6 2.8 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.5 59.3 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.5 6.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.5 1.5 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.5 15.0 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.5 5.3 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.5 5.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.4 3.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.4 1.3 GO:1902871 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.4 2.5 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.4 2.3 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.4 2.2 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.4 2.8 GO:0009313 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.3 3.4 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.3 2.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.3 1.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.3 4.7 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.3 8.0 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.3 10.6 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.3 4.7 GO:0042407 cristae formation(GO:0042407)
0.3 1.9 GO:0015722 canalicular bile acid transport(GO:0015722)
0.3 1.3 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.3 1.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 1.0 GO:1900623 positive regulation of mast cell cytokine production(GO:0032765) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 1.4 GO:0018992 germ-line sex determination(GO:0018992)
0.2 4.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 0.9 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 0.6 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.2 0.4 GO:0042374 menaquinone metabolic process(GO:0009233) phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.2 1.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 3.0 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.2 0.5 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2 1.7 GO:0098881 synaptic vesicle docking(GO:0016081) exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 1.6 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.2 28.0 GO:0009308 amine metabolic process(GO:0009308)
0.2 0.9 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 2.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.9 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.4 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 1.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 1.7 GO:0015695 organic cation transport(GO:0015695)
0.1 1.1 GO:0060214 endocardium formation(GO:0060214)
0.1 0.6 GO:1904970 brush border assembly(GO:1904970)
0.1 0.3 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.1 1.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.7 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 0.8 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 2.6 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 0.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 1.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.4 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1 1.0 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 1.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996) regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.1 1.5 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.9 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 1.3 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.8 GO:0046959 habituation(GO:0046959)
0.1 0.3 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 1.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.3 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 0.9 GO:0048241 epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.1 2.2 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.1 1.8 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.2 GO:2000506 positive regulation of small intestine smooth muscle contraction(GO:1904349) negative regulation of energy homeostasis(GO:2000506)
0.1 1.3 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.4 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 0.7 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.5 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.3 GO:0050968 sensory perception of sour taste(GO:0050915) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 0.9 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 2.7 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 1.0 GO:0003181 atrioventricular valve morphogenesis(GO:0003181)
0.1 0.4 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.1 1.6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 1.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 1.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.6 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 7.8 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 2.9 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.0 3.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 2.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.7 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 1.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 1.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.8 GO:0034063 stress granule assembly(GO:0034063)
0.0 5.2 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 5.9 GO:0008643 carbohydrate transport(GO:0008643)
0.0 1.2 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.0 0.4 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.7 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.5 GO:0061512 protein localization to cilium(GO:0061512)
0.0 1.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 1.1 GO:0003341 cilium movement(GO:0003341)
0.0 2.7 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.2 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 3.7 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.4 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 1.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.7 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.0 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0 0.3 GO:0048485 sympathetic nervous system development(GO:0048485)
0.0 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:1901317 regulation of sperm motility(GO:1901317)
0.0 0.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.5 GO:0043030 regulation of macrophage activation(GO:0043030)
0.0 1.7 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.7 GO:0048678 response to axon injury(GO:0048678)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 1.2 GO:0030216 keratinocyte differentiation(GO:0030216)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0032311 angiogenin-PRI complex(GO:0032311)
2.2 33.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
1.5 6.0 GO:0097447 dendritic tree(GO:0097447)
0.6 4.7 GO:0061617 MICOS complex(GO:0061617)
0.5 8.9 GO:0043203 axon hillock(GO:0043203)
0.5 1.9 GO:0046691 intracellular canaliculus(GO:0046691)
0.4 1.5 GO:0071821 FANCM-MHF complex(GO:0071821)
0.3 24.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 1.7 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.2 1.9 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 4.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 0.9 GO:1990716 axonemal central apparatus(GO:1990716)
0.2 1.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 58.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 2.6 GO:0000243 commitment complex(GO:0000243)
0.2 1.0 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 2.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 5.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 2.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 3.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 8.4 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.1 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.6 GO:0005927 muscle tendon junction(GO:0005927)
0.1 1.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.9 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 10.0 GO:0005604 basement membrane(GO:0005604)
0.1 2.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.9 GO:0001520 outer dense fiber(GO:0001520)
0.1 2.1 GO:0034451 centriolar satellite(GO:0034451)
0.1 13.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 2.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 2.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 4.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.1 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 3.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 1.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.2 GO:0005811 lipid particle(GO:0005811)
0.0 4.5 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 5.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 5.6 GO:0043197 dendritic spine(GO:0043197)
0.0 1.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 39.2 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 2.3 GO:0005814 centriole(GO:0005814)
0.0 0.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 1.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 3.5 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 6.2 GO:0019866 organelle inner membrane(GO:0019866)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 3.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 57.6 GO:0003996 acyl-CoA ligase activity(GO:0003996)
3.6 21.5 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
3.5 28.1 GO:0008172 S-methyltransferase activity(GO:0008172)
2.4 7.1 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
2.2 13.0 GO:0032810 sterol response element binding(GO:0032810)
1.9 7.7 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.9 5.8 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
1.7 8.4 GO:0051185 coenzyme transporter activity(GO:0051185)
1.3 33.1 GO:0051787 misfolded protein binding(GO:0051787)
1.1 3.4 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
1.1 4.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
1.0 3.8 GO:0050436 microfibril binding(GO:0050436)
0.9 10.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.8 12.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.8 24.3 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.7 3.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.7 4.1 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.6 2.8 GO:0052794 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.5 6.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5 10.4 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.5 2.4 GO:0038181 bile acid receptor activity(GO:0038181)
0.5 1.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.4 2.5 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.4 2.3 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.4 3.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 1.7 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.3 5.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 4.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 2.6 GO:0004046 aminoacylase activity(GO:0004046)
0.3 11.1 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.3 2.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 5.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) aromatase activity(GO:0070330)
0.3 1.7 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.3 1.9 GO:0004969 histamine receptor activity(GO:0004969)
0.3 1.3 GO:2001069 glycogen binding(GO:2001069)
0.3 6.1 GO:0016805 dipeptidase activity(GO:0016805)
0.3 2.7 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.2 2.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 4.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.6 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 0.8 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.2 1.7 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 1.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 5.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 3.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 2.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 1.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 2.6 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 9.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 5.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 3.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.4 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 2.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 7.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.9 GO:0015250 water channel activity(GO:0015250)
0.1 1.4 GO:0003796 lysozyme activity(GO:0003796)
0.1 10.6 GO:0020037 heme binding(GO:0020037)
0.1 2.1 GO:0045499 chemorepellent activity(GO:0045499)
0.1 8.2 GO:0005507 copper ion binding(GO:0005507)
0.1 0.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 2.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.8 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.2 GO:0031768 ghrelin receptor binding(GO:0031768)
0.1 1.5 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 1.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 2.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 2.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.8 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.9 GO:0043495 protein anchor(GO:0043495)
0.0 2.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 6.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 1.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 4.4 GO:0000149 SNARE binding(GO:0000149)
0.0 1.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 2.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.5 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.3 GO:0003727 single-stranded RNA binding(GO:0003727)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 32.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.3 15.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 9.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 11.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 2.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 5.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
1.1 12.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.9 12.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.7 10.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.3 2.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 6.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 31.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 4.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 12.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 2.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 9.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 14.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 4.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 1.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 2.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 3.0 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 3.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 7.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 6.5 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins