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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Twist1

Z-value: 0.85

Motif logo

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Transcription factors associated with Twist1

Gene Symbol Gene ID Gene Info
Twist1
ENSMUSG00000035799.7 Twist1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Twist1mm39_v1_chr12_+_34007645_34007670-0.048.0e-01Click!

Activity profile of Twist1 motif

Sorted Z-values of Twist1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Twist1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_-_41012435 19.40 ENSMUST00000031931.6
2210010C04Rik
RIKEN cDNA 2210010C04 gene
chr6_+_30639217 16.72 ENSMUST00000031806.10
Cpa1
carboxypeptidase A1, pancreatic
chr8_-_106660470 12.46 ENSMUST00000034368.8
Ctrl
chymotrypsin-like
chr7_-_142233270 6.19 ENSMUST00000162317.2
ENSMUST00000125933.2
ENSMUST00000105931.8
ENSMUST00000105930.8
ENSMUST00000105933.8
ENSMUST00000105932.2
ENSMUST00000000220.3
Ins2
insulin II
chr15_+_100202642 1.63 ENSMUST00000067752.5
ENSMUST00000229588.2
Mettl7a1
methyltransferase like 7A1
chr18_-_16942289 1.47 ENSMUST00000025166.14
Cdh2
cadherin 2
chr6_-_40976413 1.30 ENSMUST00000166306.3
Gm2663
predicted gene 2663
chr19_+_38995463 1.24 ENSMUST00000025966.5
Cyp2c55
cytochrome P450, family 2, subfamily c, polypeptide 55
chr6_+_40941688 1.21 ENSMUST00000076638.7
1810009J06Rik
RIKEN cDNA 1810009J06 gene
chr7_+_127400016 1.18 ENSMUST00000106271.2
ENSMUST00000138432.2
Hsd3b7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr9_+_83430363 1.14 ENSMUST00000188241.7
ENSMUST00000113215.10
Sh3bgrl2
SH3 domain binding glutamic acid-rich protein like 2
chr2_+_71811526 1.01 ENSMUST00000090826.12
ENSMUST00000102698.10
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr5_+_8943943 0.98 ENSMUST00000196067.2
Abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr1_+_171265103 0.91 ENSMUST00000043839.5
F11r
F11 receptor
chr2_-_26012751 0.91 ENSMUST00000140993.2
ENSMUST00000028300.6
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr17_+_37253802 0.90 ENSMUST00000040498.12
Rnf39
ring finger protein 39
chr4_-_57143437 0.84 ENSMUST00000095076.10
ENSMUST00000030142.4
Epb41l4b
erythrocyte membrane protein band 4.1 like 4b
chr15_-_100497863 0.82 ENSMUST00000073837.13
Pou6f1
POU domain, class 6, transcription factor 1
chr16_+_31482658 0.78 ENSMUST00000115201.8
Dlg1
discs large MAGUK scaffold protein 1
chr16_-_59421342 0.75 ENSMUST00000172910.3
Crybg3
beta-gamma crystallin domain containing 3
chr2_+_29855572 0.72 ENSMUST00000113719.9
ENSMUST00000113717.8
ENSMUST00000113741.8
ENSMUST00000100225.9
ENSMUST00000095083.11
ENSMUST00000046257.14
Sptan1
spectrin alpha, non-erythrocytic 1
chr2_-_65068917 0.71 ENSMUST00000090896.10
ENSMUST00000155082.2
Cobll1
Cobl-like 1
chr7_-_70010341 0.64 ENSMUST00000032768.15
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr8_+_106032205 0.60 ENSMUST00000109375.4
ENSMUST00000212033.2
Elmo3
engulfment and cell motility 3
chr17_+_74645936 0.58 ENSMUST00000224711.2
ENSMUST00000024869.8
ENSMUST00000233611.2
Spast
spastin
chr8_-_78337297 0.58 ENSMUST00000141202.2
ENSMUST00000152168.8
Tmem184c
transmembrane protein 184C
chr16_+_31482745 0.57 ENSMUST00000100001.10
ENSMUST00000064477.14
Dlg1
discs large MAGUK scaffold protein 1
chr9_+_60701749 0.57 ENSMUST00000214354.2
ENSMUST00000050183.7
ENSMUST00000217656.2
Uaca
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr2_+_31777273 0.56 ENSMUST00000138325.8
ENSMUST00000028187.7
Lamc3
laminin gamma 3
chr6_-_134543876 0.53 ENSMUST00000032322.15
ENSMUST00000126836.4
Lrp6
low density lipoprotein receptor-related protein 6
chr13_+_104246245 0.51 ENSMUST00000044385.14
Sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr13_-_104246084 0.51 ENSMUST00000224945.2
ENSMUST00000109315.5
Nln
neurolysin (metallopeptidase M3 family)
chr7_-_80051455 0.49 ENSMUST00000120753.3
Furin
furin (paired basic amino acid cleaving enzyme)
chr4_-_123458465 0.49 ENSMUST00000238731.2
Macf1
microtubule-actin crosslinking factor 1
chr12_+_4642987 0.48 ENSMUST00000062580.8
ENSMUST00000220311.2
Itsn2
intersectin 2
chr9_-_44920899 0.47 ENSMUST00000102832.3
Cd3e
CD3 antigen, epsilon polypeptide
chr9_-_114673158 0.43 ENSMUST00000047013.4
Cmtm8
CKLF-like MARVEL transmembrane domain containing 8
chr11_+_102993865 0.41 ENSMUST00000152971.2
Acbd4
acyl-Coenzyme A binding domain containing 4
chr19_-_11243530 0.39 ENSMUST00000169159.3
Ms4a1
membrane-spanning 4-domains, subfamily A, member 1
chr10_+_70080913 0.38 ENSMUST00000046807.7
Slc16a9
solute carrier family 16 (monocarboxylic acid transporters), member 9
chr13_+_73775001 0.38 ENSMUST00000022104.9
Tert
telomerase reverse transcriptase
chr15_+_100251030 0.38 ENSMUST00000075675.7
ENSMUST00000088142.6
ENSMUST00000176287.2
Methig1
Mettl7a2
methyltransferase hypoxia inducible domain containing 1
methyltransferase like 7A2
chr9_+_57037974 0.37 ENSMUST00000160147.8
ENSMUST00000161663.8
ENSMUST00000034836.16
ENSMUST00000161182.8
Man2c1
mannosidase, alpha, class 2C, member 1
chr19_+_5790918 0.36 ENSMUST00000081496.6
Ltbp3
latent transforming growth factor beta binding protein 3
chr14_+_101967343 0.33 ENSMUST00000100337.10
Lmo7
LIM domain only 7
chr5_+_31454939 0.32 ENSMUST00000201675.3
Gckr
glucokinase regulatory protein
chr18_+_4920513 0.31 ENSMUST00000126977.8
Svil
supervillin
chrX_+_56098908 0.30 ENSMUST00000114751.9
ENSMUST00000088652.6
Htatsf1
HIV TAT specific factor 1
chr5_+_149335214 0.30 ENSMUST00000093110.12
Medag
mesenteric estrogen dependent adipogenesis
chr6_-_83808717 0.29 ENSMUST00000058383.9
Paip2b
poly(A) binding protein interacting protein 2B
chr7_+_82516491 0.29 ENSMUST00000082237.7
Mex3b
mex3 RNA binding family member B
chr13_-_58261406 0.28 ENSMUST00000160860.9
Klhl3
kelch-like 3
chr1_+_90926443 0.27 ENSMUST00000189505.7
ENSMUST00000185531.7
ENSMUST00000068116.13
Lrrfip1
leucine rich repeat (in FLII) interacting protein 1
chr2_-_142743438 0.26 ENSMUST00000230763.2
ENSMUST00000043589.8
Kif16b
kinesin family member 16B
chr9_+_83430395 0.26 ENSMUST00000188030.2
Sh3bgrl2
SH3 domain binding glutamic acid-rich protein like 2
chr5_-_35886605 0.26 ENSMUST00000070203.14
Sh3tc1
SH3 domain and tetratricopeptide repeats 1
chr3_+_89958940 0.25 ENSMUST00000159064.8
4933434E20Rik
RIKEN cDNA 4933434E20 gene
chr11_+_99755302 0.25 ENSMUST00000092694.4
Gm11559
predicted gene 11559
chr2_-_142743354 0.25 ENSMUST00000211861.2
Kif16b
kinesin family member 16B
chr7_+_24310171 0.24 ENSMUST00000206422.2
Phldb3
pleckstrin homology like domain, family B, member 3
chr5_+_31454787 0.23 ENSMUST00000201166.4
ENSMUST00000072228.9
Gckr
glucokinase regulatory protein
chr10_+_61010983 0.22 ENSMUST00000143207.8
ENSMUST00000148181.8
ENSMUST00000151886.8
Tbata
thymus, brain and testes associated
chr9_+_65172455 0.22 ENSMUST00000048762.8
Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr11_+_109541400 0.22 ENSMUST00000106676.8
Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
chr8_+_53964721 0.22 ENSMUST00000211424.2
ENSMUST00000033920.6
Aga
aspartylglucosaminidase
chr18_-_67857594 0.21 ENSMUST00000120934.8
ENSMUST00000025420.14
ENSMUST00000122412.2
Ptpn2
protein tyrosine phosphatase, non-receptor type 2
chr7_-_30814652 0.19 ENSMUST00000168884.8
ENSMUST00000108102.9
Hpn
hepsin
chr6_-_29164981 0.19 ENSMUST00000007993.16
Rbm28
RNA binding motif protein 28
chr13_+_104246259 0.18 ENSMUST00000160322.8
ENSMUST00000159574.2
Sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr11_+_109541747 0.17 ENSMUST00000049527.7
Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
chr7_-_4448180 0.15 ENSMUST00000138798.2
Rdh13
retinol dehydrogenase 13 (all-trans and 9-cis)
chr11_+_69826603 0.15 ENSMUST00000018698.12
Ybx2
Y box protein 2
chr15_-_57755753 0.15 ENSMUST00000022993.7
Derl1
Der1-like domain family, member 1
chr15_+_100232810 0.14 ENSMUST00000075420.6
Mettl7a3
methyltransferase like 7A3
chr9_-_54569128 0.14 ENSMUST00000034822.12
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr19_+_28941292 0.14 ENSMUST00000045674.4
Plpp6
phospholipid phosphatase 6
chr11_+_69826719 0.13 ENSMUST00000149194.8
Ybx2
Y box protein 2
chr4_-_126362372 0.13 ENSMUST00000097888.10
ENSMUST00000239399.2
Ago1
argonaute RISC catalytic subunit 1
chr17_+_45874800 0.12 ENSMUST00000224905.2
ENSMUST00000226086.2
ENSMUST00000041353.7
Slc35b2
solute carrier family 35, member B2
chr6_-_124410452 0.12 ENSMUST00000124998.2
ENSMUST00000238807.2
Clstn3
calsyntenin 3
chr2_+_107120934 0.12 ENSMUST00000037012.3
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr9_-_63509747 0.11 ENSMUST00000080527.12
ENSMUST00000042322.11
Iqch
IQ motif containing H
chr3_-_104869237 0.11 ENSMUST00000029429.6
Wnt2b
wingless-type MMTV integration site family, member 2B
chr7_-_4448631 0.11 ENSMUST00000008579.14
Rdh13
retinol dehydrogenase 13 (all-trans and 9-cis)
chr8_-_71834543 0.11 ENSMUST00000002466.9
Nr2f6
nuclear receptor subfamily 2, group F, member 6
chr11_-_76070325 0.11 ENSMUST00000167114.8
ENSMUST00000094015.11
ENSMUST00000108419.9
ENSMUST00000170730.3
ENSMUST00000129256.2
ENSMUST00000056601.11
Vps53
VPS53 GARP complex subunit
chr11_+_76070483 0.10 ENSMUST00000129853.8
Tlcd3a
TLC domain containing 3A
chr9_-_57375269 0.08 ENSMUST00000215059.2
ENSMUST00000046587.8
ENSMUST00000214256.2
Scamp5
secretory carrier membrane protein 5
chr17_+_34029484 0.08 ENSMUST00000048560.11
ENSMUST00000172649.8
ENSMUST00000173789.2
Kank3
KN motif and ankyrin repeat domains 3
chr5_-_23880939 0.07 ENSMUST00000196388.5
Srpk2
serine/arginine-rich protein specific kinase 2
chr7_+_6442835 0.07 ENSMUST00000168341.2
Olfr1344
olfactory receptor 1344
chr1_+_174329361 0.06 ENSMUST00000030039.13
Fmn2
formin 2
chr2_-_79959802 0.06 ENSMUST00000102653.8
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr18_+_61044830 0.06 ENSMUST00000040359.6
Arsi
arylsulfatase i
chr16_+_18630522 0.05 ENSMUST00000115578.10
Ufd1
ubiquitin recognition factor in ER-associated degradation 1
chr7_-_84339045 0.04 ENSMUST00000209165.2
Zfand6
zinc finger, AN1-type domain 6
chr2_-_45007407 0.04 ENSMUST00000176438.9
Zeb2
zinc finger E-box binding homeobox 2
chr11_-_113600346 0.04 ENSMUST00000173655.8
ENSMUST00000100248.6
Cpsf4l
cleavage and polyadenylation specific factor 4-like
chr2_-_32674435 0.04 ENSMUST00000102813.2
Cfap157
cilia and flagella associated protein 157
chrX_-_18327610 0.03 ENSMUST00000044188.5
Dipk2b
divergent protein kinase domain 2B
chr17_+_75772475 0.03 ENSMUST00000095204.6
Rasgrp3
RAS, guanyl releasing protein 3
chr11_-_94440025 0.03 ENSMUST00000040487.4
Rsad1
radical S-adenosyl methionine domain containing 1
chr8_-_112120442 0.02 ENSMUST00000038475.9
Fa2h
fatty acid 2-hydroxylase
chr4_-_135221810 0.02 ENSMUST00000105856.9
Nipal3
NIPA-like domain containing 3
chr12_+_102915102 0.02 ENSMUST00000101099.12
Unc79
unc-79 homolog
chr9_-_54568950 0.01 ENSMUST00000128624.2
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr11_-_109188892 0.01 ENSMUST00000106706.8
Rgs9
regulator of G-protein signaling 9
chr15_-_76004395 0.01 ENSMUST00000239552.1
EPPK1
epiplakin 1
chr9_-_83688294 0.00 ENSMUST00000034796.14
ENSMUST00000183614.2
Elovl4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr18_+_40390013 0.00 ENSMUST00000096572.2
ENSMUST00000236889.2
Kctd16
potassium channel tetramerisation domain containing 16

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
0.3 1.3 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.3 1.0 GO:1903412 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
0.3 0.9 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.2 1.5 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.2 1.0 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.2 0.5 GO:0061348 planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
0.2 0.6 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.4 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.5 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.4 GO:0036363 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 1.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 1.2 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.5 GO:0009750 response to fructose(GO:0009750)
0.1 0.5 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 0.2 GO:1903972 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104) regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.1 0.2 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.6 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.5 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.4 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.6 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.6 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.4 GO:0046415 urate metabolic process(GO:0046415)
0.0 46.5 GO:0006508 proteolysis(GO:0006508)
0.0 0.0 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.6 GO:0014002 astrocyte development(GO:0014002)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.1 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.3 GO:0072697 protein localization to cell cortex(GO:0072697)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0044316 cone cell pedicle(GO:0044316)
0.2 5.7 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.2 1.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.5 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.7 GO:0032437 cuticular plate(GO:0032437)
0.1 0.6 GO:0043293 apoptosome(GO:0043293)
0.1 1.5 GO:0016342 catenin complex(GO:0016342)
0.1 1.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.9 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0000938 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.0 2.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0036501 UFD1-NPL4 complex(GO:0036501)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 37.0 GO:0005615 extracellular space(GO:0005615)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 16.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 1.2 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.3 1.2 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
0.2 1.3 GO:0097016 L27 domain binding(GO:0097016)
0.2 0.5 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.2 1.0 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 6.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 35.2 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 0.5 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.2 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.4 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein