Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Zfp423

Z-value: 1.00

Motif logo

logo of

Transcription factors associated with Zfp423

Gene Symbol Gene ID Gene Info
Zfp423
ENSMUSG00000045333.16 Zfp423

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp423mm39_v1_chr8_-_88531018_885310670.455.5e-03Click!

Activity profile of Zfp423 motif

Sorted Z-values of Zfp423 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp423

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_86605146 6.21 ENSMUST00000043400.9
Asprv1
aspartic peptidase, retroviral-like 1
chr12_+_109425769 5.29 ENSMUST00000173812.2
Dlk1
delta like non-canonical Notch ligand 1
chr10_+_60185093 3.28 ENSMUST00000105459.2
Vsir
V-set immunoregulatory receptor
chr9_-_37464200 3.23 ENSMUST00000065668.12
Nrgn
neurogranin
chrX_-_74174450 3.22 ENSMUST00000114092.8
ENSMUST00000132501.8
ENSMUST00000153318.8
ENSMUST00000155742.2
Mpp1
membrane protein, palmitoylated
chrX_-_74174608 3.17 ENSMUST00000033775.9
Mpp1
membrane protein, palmitoylated
chr11_+_54793569 3.02 ENSMUST00000082430.11
Gpx3
glutathione peroxidase 3
chr15_+_78128990 2.99 ENSMUST00000096357.12
Ncf4
neutrophil cytosolic factor 4
chr19_+_10019023 2.94 ENSMUST00000237672.2
Fads3
fatty acid desaturase 3
chr2_+_154633265 2.84 ENSMUST00000140713.3
ENSMUST00000137333.8
Raly
a
hnRNP-associated with lethal yellow
nonagouti
chrX_-_74174524 2.83 ENSMUST00000114091.8
Mpp1
membrane protein, palmitoylated
chr11_+_54793743 2.47 ENSMUST00000149324.3
Gpx3
glutathione peroxidase 3
chr4_-_106321363 2.23 ENSMUST00000049507.6
Pcsk9
proprotein convertase subtilisin/kexin type 9
chr15_+_78129040 2.12 ENSMUST00000133618.3
Ncf4
neutrophil cytosolic factor 4
chr17_-_23864237 1.97 ENSMUST00000024696.9
Mmp25
matrix metallopeptidase 25
chr4_+_126915104 1.92 ENSMUST00000030623.8
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr19_+_7245591 1.86 ENSMUST00000066646.12
Rcor2
REST corepressor 2
chr8_-_84425724 1.85 ENSMUST00000005616.16
Pkn1
protein kinase N1
chr17_+_69463786 1.82 ENSMUST00000112680.8
ENSMUST00000080208.7
ENSMUST00000225977.2
Epb41l3
erythrocyte membrane protein band 4.1 like 3
chr19_+_10018914 1.62 ENSMUST00000115995.4
Fads3
fatty acid desaturase 3
chr16_+_49675969 1.59 ENSMUST00000229101.2
ENSMUST00000230836.2
ENSMUST00000229206.2
ENSMUST00000084838.14
ENSMUST00000230281.2
Cd47
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr5_-_22549688 1.57 ENSMUST00000062372.14
ENSMUST00000161356.8
Reln
reelin
chr7_-_141023199 1.52 ENSMUST00000106005.9
Pidd1
p53 induced death domain protein 1
chr4_+_129407374 1.50 ENSMUST00000062356.7
Marcksl1
MARCKS-like 1
chr16_+_17307503 1.43 ENSMUST00000023448.15
Aifm3
apoptosis-inducing factor, mitochondrion-associated 3
chrX_+_100298134 1.28 ENSMUST00000062000.6
Foxo4
forkhead box O4
chr19_+_6451667 1.28 ENSMUST00000113471.3
ENSMUST00000113469.3
Rasgrp2
RAS, guanyl releasing protein 2
chr7_-_5017642 1.14 ENSMUST00000207412.2
ENSMUST00000077385.15
ENSMUST00000165320.3
Fiz1
Flt3 interacting zinc finger protein 1
chr7_-_126625617 1.13 ENSMUST00000032916.6
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr4_-_116982804 1.07 ENSMUST00000183310.2
Btbd19
BTB (POZ) domain containing 19
chr2_+_38229270 1.06 ENSMUST00000143783.9
Lhx2
LIM homeobox protein 2
chr7_+_127084283 0.88 ENSMUST00000048896.8
Fbrs
fibrosin
chr19_-_10847121 0.87 ENSMUST00000120524.2
ENSMUST00000025645.14
Tmem132a
transmembrane protein 132A
chr15_-_103242697 0.86 ENSMUST00000229373.2
Zfp385a
zinc finger protein 385A
chr7_+_18737944 0.73 ENSMUST00000053713.5
Irf2bp1
interferon regulatory factor 2 binding protein 1
chr2_+_164627743 0.62 ENSMUST00000174070.8
ENSMUST00000172577.8
ENSMUST00000056181.7
Snx21
sorting nexin family member 21
chr9_+_120321557 0.60 ENSMUST00000007139.6
Eif1b
eukaryotic translation initiation factor 1B
chr3_+_114697710 0.60 ENSMUST00000081752.13
Olfm3
olfactomedin 3
chr17_-_32385826 0.53 ENSMUST00000087723.5
Notch3
notch 3
chr2_+_164627913 0.50 ENSMUST00000152471.2
Snx21
sorting nexin family member 21
chr8_+_27750349 0.49 ENSMUST00000033880.7
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr4_+_154321982 0.47 ENSMUST00000152159.8
Megf6
multiple EGF-like-domains 6
chr17_-_37178079 0.47 ENSMUST00000025329.13
ENSMUST00000174195.8
Trim15
tripartite motif-containing 15
chr17_+_69463846 0.47 ENSMUST00000238898.2
Epb41l3
erythrocyte membrane protein band 4.1 like 3
chr10_-_14581203 0.47 ENSMUST00000149485.2
ENSMUST00000154132.8
Vta1
vesicle (multivesicular body) trafficking 1
chr19_+_41818409 0.44 ENSMUST00000087155.5
Frat1
frequently rearranged in advanced T cell lymphomas
chr6_+_7844759 0.43 ENSMUST00000040159.6
C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr7_-_19192672 0.43 ENSMUST00000239292.2
ENSMUST00000085715.7
Mark4
MAP/microtubule affinity regulating kinase 4
chr17_-_23939700 0.39 ENSMUST00000201734.4
1520401A03Rik
RIKEN cDNA 1520401A03 gene
chr4_-_148711211 0.36 ENSMUST00000186947.7
ENSMUST00000105699.8
Tardbp
TAR DNA binding protein
chr2_+_106523532 0.30 ENSMUST00000111063.8
Mpped2
metallophosphoesterase domain containing 2
chr19_-_5781503 0.29 ENSMUST00000162976.2
Znrd2
zinc ribbon domain containing 2
chr15_+_101191077 0.28 ENSMUST00000071328.7
Smim41
small integral membrane protein 41
chr15_+_101191099 0.25 ENSMUST00000191426.2
Smim41
small integral membrane protein 41
chr7_-_79443536 0.24 ENSMUST00000032760.6
Mesp1
mesoderm posterior 1
chr16_-_45474413 0.24 ENSMUST00000036732.9
BC016579
cDNA sequence, BC016579
chr16_-_20972750 0.23 ENSMUST00000170665.3
Teddm3
transmembrane epididymal family member 3
chr5_-_136594286 0.21 ENSMUST00000176172.8
Cux1
cut-like homeobox 1
chr10_-_80223475 0.20 ENSMUST00000105350.3
Mex3d
mex3 RNA binding family member D
chr18_+_34892599 0.20 ENSMUST00000097622.4
Fam53c
family with sequence similarity 53, member C
chr2_+_93017916 0.18 ENSMUST00000090554.11
Trp53i11
transformation related protein 53 inducible protein 11
chr2_+_93017887 0.14 ENSMUST00000150462.8
ENSMUST00000111266.8
Trp53i11
transformation related protein 53 inducible protein 11
chr12_-_69230760 0.14 ENSMUST00000110620.2
ENSMUST00000110619.2
ENSMUST00000054544.7
Rpl36al
ribosomal protein L36A-like
chr1_+_156386414 0.14 ENSMUST00000166172.9
ENSMUST00000027888.13
Abl2
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr17_-_25652750 0.14 ENSMUST00000159610.8
ENSMUST00000159048.8
ENSMUST00000078496.12
Cacna1h
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr7_+_63803583 0.13 ENSMUST00000085222.12
ENSMUST00000206277.2
Trpm1
transient receptor potential cation channel, subfamily M, member 1
chr11_+_81992662 0.10 ENSMUST00000000194.4
Ccl12
chemokine (C-C motif) ligand 12
chr10_+_80972089 0.09 ENSMUST00000048128.15
Zbtb7a
zinc finger and BTB domain containing 7a
chr7_+_63803663 0.02 ENSMUST00000206314.2
Trpm1
transient receptor potential cation channel, subfamily M, member 1
chr7_-_45519853 0.01 ENSMUST00000211713.2
Grin2d
glutamate receptor, ionotropic, NMDA2D (epsilon 4)
chr19_+_55730242 0.00 ENSMUST00000111662.11
ENSMUST00000041717.14
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr10_+_80972368 0.00 ENSMUST00000119606.8
ENSMUST00000146895.2
ENSMUST00000121840.8
Zbtb7a
zinc finger and BTB domain containing 7a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.6 2.2 GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805)
0.5 3.3 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.4 1.6 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.2 2.0 GO:0060022 hard palate development(GO:0060022)
0.2 9.2 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.2 0.9 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 2.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 1.8 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 5.1 GO:0045730 respiratory burst(GO:0045730)
0.2 5.5 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.2 1.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.2 1.9 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 5.3 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 1.6 GO:0008228 opsonization(GO:0008228)
0.1 1.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.5 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.5 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.1 1.5 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 0.2 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.1 3.2 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.1 0.5 GO:0072103 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.1 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.1 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 1.4 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 6.1 GO:0016485 protein processing(GO:0016485)
0.0 1.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.7 GO:0042462 eye photoreceptor cell development(GO:0042462)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:1990666 PCSK9-LDLR complex(GO:1990666) PCSK9-AnxA2 complex(GO:1990667)
0.3 5.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 3.2 GO:0044327 dendritic spine head(GO:0044327)
0.2 1.9 GO:0042382 paraspeckles(GO:0042382)
0.1 2.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 9.2 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 1.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 2.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 7.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.9 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.5 2.8 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.5 1.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.4 5.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 5.5 GO:0008430 selenium binding(GO:0008430)
0.3 1.6 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 6.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 1.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 3.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 2.0 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 1.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 5.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.3 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.5 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.1 5.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 5.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)