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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Zkscan1

Z-value: 1.82

Motif logo

Transcription factors associated with Zkscan1

Gene Symbol Gene ID Gene Info
ENSMUSG00000029729.13 Zkscan1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zkscan1mm39_v1_chr5_+_138083345_138083410-0.326.1e-02Click!

Activity profile of Zkscan1 motif

Sorted Z-values of Zkscan1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zkscan1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_79716876 11.26 ENSMUST00000166201.2
proteinase 3
chr17_-_33937565 8.59 ENSMUST00000174040.2
ENSMUST00000173015.8
ENSMUST00000066121.13
ENSMUST00000186022.7
ENSMUST00000173329.8
ENSMUST00000172767.9
membrane associated ring-CH-type finger 2
chr15_-_74983786 8.20 ENSMUST00000191451.2
ENSMUST00000100542.10
lymphocyte antigen 6 complex, locus C2
chr8_-_72178340 6.78 ENSMUST00000153800.8
ENSMUST00000146100.8
FCH domain only 1
chr15_-_78456898 5.97 ENSMUST00000043214.8
Rac family small GTPase 2
chr2_+_84564394 5.68 ENSMUST00000238573.2
ENSMUST00000090729.9
yippee like 4
chr17_+_29042640 5.48 ENSMUST00000233088.2
ENSMUST00000233182.2
ENSMUST00000233520.2
bromodomain and PHD finger containing, 3
chr9_+_51124983 5.31 ENSMUST00000034554.9
POU domain, class 2, associating factor 1
chrX_-_48886577 5.27 ENSMUST00000033442.14
ENSMUST00000114891.2
immunoglobulin superfamily, member 1
chr15_+_75027089 5.11 ENSMUST00000190262.2
lymphocyte antigen 6 complex, locus G
chr4_-_140805613 4.59 ENSMUST00000030760.15
NECAP endocytosis associated 2
chr15_-_74920518 4.42 ENSMUST00000185372.2
ENSMUST00000187347.7
ENSMUST00000188845.7
ENSMUST00000185200.7
ENSMUST00000179762.8
ENSMUST00000191216.7
ENSMUST00000065408.16
lymphocyte antigen 6 complex, locus C1
chr17_+_29042544 4.38 ENSMUST00000140587.9
bromodomain and PHD finger containing, 3
chr7_-_132415257 4.29 ENSMUST00000097999.9
family with sequence similarity 53, member B
chr8_+_95712151 4.10 ENSMUST00000212799.2
adhesion G protein-coupled receptor G1
chr19_-_61216834 4.03 ENSMUST00000076046.7
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr12_-_79054050 3.67 ENSMUST00000056660.13
ENSMUST00000174721.8
transmembrane protein 229B
chr9_-_103357564 3.42 ENSMUST00000124310.5
beaded filament structural protein 2, phakinin
chr13_+_50571889 3.33 ENSMUST00000046974.5
F-box and WD-40 domain protein 17
chr2_+_118428690 3.28 ENSMUST00000038341.8
BUB1B, mitotic checkpoint serine/threonine kinase
chr10_-_79624758 3.26 ENSMUST00000020573.13
protease, serine 57
chr5_+_125518736 3.22 ENSMUST00000198811.2
Bri3 binding protein
chr10_-_81360059 3.17 ENSMUST00000043709.8
guanine nucleotide binding protein, alpha 15
chr6_-_83513222 3.12 ENSMUST00000075161.12
actin, gamma 2, smooth muscle, enteric
chr5_-_140307280 3.01 ENSMUST00000031534.9
MAD1 mitotic arrest deficient 1-like 1
chr7_-_132414823 3.00 ENSMUST00000106165.8
family with sequence similarity 53, member B
chr7_-_126399778 2.95 ENSMUST00000141355.4
aldolase A, fructose-bisphosphate
chrX_+_20736405 2.90 ENSMUST00000115342.10
ENSMUST00000009530.5
tissue inhibitor of metalloproteinase 1
chr6_+_47854138 2.80 ENSMUST00000061890.8
zinc finger protein 282
chr12_+_111387023 2.78 ENSMUST00000220852.2
exocyst complex component 3-like 4
chr2_+_156681927 2.39 ENSMUST00000081335.13
TGFB-induced factor homeobox 2
chr2_+_156681991 2.31 ENSMUST00000073352.10
TGFB-induced factor homeobox 2
chr6_-_83513184 2.30 ENSMUST00000205926.2
actin, gamma 2, smooth muscle, enteric
chr7_-_97811525 2.10 ENSMUST00000107112.2
calpain 5
chr19_+_53298906 2.07 ENSMUST00000003870.15
MAX interactor 1, dimerization protein
chr19_+_12775938 1.98 ENSMUST00000025601.8
leupaxin
chr7_+_96730763 1.95 ENSMUST00000004622.7
growth factor receptor bound protein 2-associated protein 2
chr11_+_104468107 1.83 ENSMUST00000106956.10
myosin, light polypeptide 4
chr15_-_74855264 1.80 ENSMUST00000023250.11
ENSMUST00000166694.2
lymphocyte antigen 6 complex, locus I
chr16_+_90182895 1.75 ENSMUST00000065856.8
hormonally upregulated Neu-associated kinase
chr9_+_118881838 1.48 ENSMUST00000051386.13
ENSMUST00000074734.13
villin-like
chr6_-_122317484 1.42 ENSMUST00000112600.9
polyhomeotic 1
chr10_-_79390911 1.39 ENSMUST00000170018.2
ENSMUST00000062855.15
ENSMUST00000165778.8
ENSMUST00000165028.8
MIER family member 2
chr17_+_25105617 1.35 ENSMUST00000117890.8
ENSMUST00000168265.8
ENSMUST00000120943.8
ENSMUST00000068508.13
ENSMUST00000119829.8
splA/ryanodine receptor domain and SOCS box containing 3
chr5_+_123532819 1.25 ENSMUST00000111596.8
ENSMUST00000068237.12
MLX interacting protein
chr11_+_69871952 1.22 ENSMUST00000108593.8
CTD nuclear envelope phosphatase 1
chr2_+_172235702 1.16 ENSMUST00000099061.9
ENSMUST00000103073.9
Cas scaffolding protein family member 4
chr7_-_132415408 1.15 ENSMUST00000134946.3
family with sequence similarity 53, member B
chr11_+_78717398 1.15 ENSMUST00000147875.9
ENSMUST00000141321.2
LYR motif containing 9
chr11_-_69872050 1.14 ENSMUST00000108594.8
elongator acetyltransferase complex subunit 5
chr7_+_28834276 1.13 ENSMUST00000161522.8
ENSMUST00000204845.3
ENSMUST00000205027.3
ENSMUST00000204194.3
ENSMUST00000203070.3
ENSMUST00000203380.3
RAS guanyl releasing protein 4
chr3_+_89043440 1.12 ENSMUST00000047111.13
pyruvate kinase liver and red blood cell
chr15_+_101308935 1.11 ENSMUST00000147662.8
keratin 7
chr2_+_172235820 1.08 ENSMUST00000109136.3
ENSMUST00000228775.2
Cas scaffolding protein family member 4
chr2_+_31135813 1.08 ENSMUST00000000199.8
neuronal calcium sensor 1
chr18_+_61238908 1.03 ENSMUST00000115268.4
colony stimulating factor 1 receptor
chr5_+_64969679 1.01 ENSMUST00000166409.6
ENSMUST00000197879.2
Kruppel-like factor 3 (basic)
chr2_+_90507552 1.01 ENSMUST00000057481.7
nucleoporin 160
chr12_+_116369017 0.99 ENSMUST00000084828.5
ENSMUST00000222469.2
ENSMUST00000221114.2
ENSMUST00000221970.2
non-SMC condensin II complex, subunit G2
chr1_+_171668173 0.92 ENSMUST00000136479.8
CD84 antigen
chr8_-_70980584 0.90 ENSMUST00000138260.8
ENSMUST00000117580.8
KxDL motif containing 1
chr2_+_112092271 0.89 ENSMUST00000028553.4
NOP10 ribonucleoprotein
chr14_-_52553764 0.82 ENSMUST00000135523.5
spalt like transcription factor 2
chr4_-_63414188 0.81 ENSMUST00000063650.10
ENSMUST00000102867.8
ENSMUST00000107393.8
ENSMUST00000084510.8
ENSMUST00000095038.8
ENSMUST00000119294.8
ENSMUST00000095037.2
ENSMUST00000063672.10
whirlin
chr5_+_125518609 0.80 ENSMUST00000049040.14
Bri3 binding protein
chr19_+_41818409 0.75 ENSMUST00000087155.5
frequently rearranged in advanced T cell lymphomas
chr8_+_4303067 0.68 ENSMUST00000011981.5
ENSMUST00000208316.2
small nuclear RNA activating complex, polypeptide 2
chr11_+_23234644 0.66 ENSMUST00000150750.3
exportin 1
chr2_+_118730823 0.63 ENSMUST00000151162.2
bromo adjacent homology domain containing 1
chrX_+_163156359 0.63 ENSMUST00000033751.8
vascular endothelial growth factor D
chr4_+_141171965 0.62 ENSMUST00000006377.13
zinc finger and BTB domain containing 17
chr10_+_79889322 0.59 ENSMUST00000105372.9
glutathione peroxidase 4
chr13_-_56283331 0.58 ENSMUST00000045788.9
ENSMUST00000016081.13
macroH2A.1 histone
chr19_+_44321531 0.57 ENSMUST00000058856.9
stearoyl-coenzyme A desaturase 4
chr6_-_122317457 0.56 ENSMUST00000160843.8
polyhomeotic 1
chr11_+_53992054 0.55 ENSMUST00000135653.8
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide
chrX_+_158155171 0.49 ENSMUST00000087143.7
eukaryotic translation initiation factor 1A, X-linked
chr5_-_134668152 0.48 ENSMUST00000036125.10
ENSMUST00000202622.4
eukaryotic translation initiation factor 4H
chr11_-_78056347 0.48 ENSMUST00000017530.4
TNF receptor associated factor 4
chr4_+_132948121 0.46 ENSMUST00000105910.2
CD164 sialomucin-like 2
chr1_-_93563406 0.45 ENSMUST00000027498.14
serine/threonine kinase 25 (yeast)
chr19_+_10914517 0.45 ENSMUST00000037261.4
prostaglandin D2 receptor 2
chr4_+_101276474 0.44 ENSMUST00000102780.8
ENSMUST00000106946.8
ENSMUST00000106945.8
adenylate kinase 4
chr1_-_93563201 0.40 ENSMUST00000133769.8
serine/threonine kinase 25 (yeast)
chr11_-_78402931 0.37 ENSMUST00000052566.8
transmembrane protein 199
chr15_-_74869684 0.35 ENSMUST00000190188.2
ENSMUST00000189068.7
ENSMUST00000186526.7
ENSMUST00000187171.2
ENSMUST00000187994.7
lymphocyte antigen 6 complex, locus A
chr7_-_118091135 0.35 ENSMUST00000178344.3
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr5_-_131567526 0.32 ENSMUST00000161374.8
autism susceptibility candidate 2
chr9_+_118881926 0.31 ENSMUST00000131647.2
villin-like
chr10_-_38998272 0.31 ENSMUST00000136546.8
family with sequence similarity 229, member B
chr6_+_57234937 0.30 ENSMUST00000228297.2
vomeronasal 1 receptor 15
chr14_-_40728839 0.28 ENSMUST00000152837.2
ENSMUST00000134715.8
peroxiredoxin like 2A
chr7_-_28661648 0.28 ENSMUST00000127210.8
actinin alpha 4
chr15_-_82505132 0.26 ENSMUST00000109515.3
cytochrome P450, family 2, subfamily d, polypeptide 34
chr15_-_79048674 0.26 ENSMUST00000230261.2
ENSMUST00000040019.5
SRY (sex determining region Y)-box 10
chr18_-_52662917 0.26 ENSMUST00000171470.8
lysyl oxidase
chr10_+_90665270 0.25 ENSMUST00000182202.8
ENSMUST00000182966.8
ankyrin repeat and sterile alpha motif domain containing 1B
chr17_+_34258411 0.24 ENSMUST00000087497.11
ENSMUST00000131134.9
ENSMUST00000235819.2
ENSMUST00000114255.9
ENSMUST00000114252.9
ENSMUST00000237989.2
collagen, type XI, alpha 2
chr9_+_98305014 0.24 ENSMUST00000052068.11
retinol binding protein 1, cellular
chr7_-_28661751 0.23 ENSMUST00000068045.14
ENSMUST00000217157.2
actinin alpha 4
chr10_+_90665639 0.22 ENSMUST00000179337.9
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_+_109263820 0.22 ENSMUST00000124209.8
tetratricopeptide repeat domain 39A
chr2_-_91795910 0.20 ENSMUST00000239257.2
diacylglycerol kinase zeta
chr2_-_127571836 0.19 ENSMUST00000028856.3
mal, T cell differentiation protein-like
chr19_-_53932581 0.17 ENSMUST00000236885.2
ENSMUST00000236098.2
ENSMUST00000236370.2
BBSome interacting protein 1
chr4_-_97472844 0.17 ENSMUST00000107067.8
ENSMUST00000107068.9
RIKEN cDNA E130114P18 gene
chr15_+_16778187 0.17 ENSMUST00000026432.8
cadherin 9
chr4_+_103476777 0.16 ENSMUST00000106827.8
disabled 1
chr6_+_83055321 0.16 ENSMUST00000165164.9
ENSMUST00000092614.9
polycomb group ring finger 1
chr9_+_106245792 0.16 ENSMUST00000172306.3
dual specificity phosphatase 7
chr1_+_90531183 0.16 ENSMUST00000186750.2
COP9 signalosome subunit 8
chr15_-_34356567 0.15 ENSMUST00000179647.2
RIKEN cDNA 9430069I07 gene
chr10_+_90665399 0.15 ENSMUST00000179694.9
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_+_120348919 0.14 ENSMUST00000058370.14
ENSMUST00000175970.8
ENSMUST00000176120.2
coiled-coil domain containing 137
chrX_-_103244703 0.13 ENSMUST00000087879.11
neurite extension and migration factor
chr2_-_73410632 0.12 ENSMUST00000028515.4
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr19_-_53932867 0.12 ENSMUST00000235688.2
ENSMUST00000235348.2
BBSome interacting protein 1
chr11_-_78313043 0.11 ENSMUST00000001122.6
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr17_+_5045178 0.11 ENSMUST00000092723.11
ENSMUST00000232180.2
ENSMUST00000115797.9
AT rich interactive domain 1B (SWI-like)
chr16_-_10265204 0.10 ENSMUST00000051118.7
trans-golgi network vesicle protein 23A
chr8_-_4375320 0.10 ENSMUST00000098950.6
ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
chr4_+_73931679 0.09 ENSMUST00000098006.9
ENSMUST00000084474.6
FERM domain containing 3
chr19_+_41471395 0.09 ENSMUST00000237208.2
ENSMUST00000238398.2
ligand dependent nuclear receptor corepressor
chr12_+_112586501 0.08 ENSMUST00000180015.9
adenylosuccinate synthetase like 1
chr2_+_153742294 0.07 ENSMUST00000088955.12
ENSMUST00000135501.3
BPI fold containing family B, member 6
chr6_+_90246088 0.07 ENSMUST00000058039.3
vomeronasal 1 receptor 54
chr19_+_43678109 0.07 ENSMUST00000081079.6
ectonucleoside triphosphate diphosphohydrolase 7
chr6_+_134012602 0.06 ENSMUST00000081028.13
ENSMUST00000111963.8
ets variant 6
chr4_+_126156118 0.06 ENSMUST00000030660.9
trafficking protein particle complex 3
chr11_+_42310557 0.05 ENSMUST00000007797.10
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr14_+_34395845 0.04 ENSMUST00000048263.14
WAPL cohesin release factor
chr19_+_5138562 0.04 ENSMUST00000238093.2
ENSMUST00000025811.6
ENSMUST00000237025.2
Yip1 interacting factor homolog A (S. cerevisiae)
chrX_-_103244784 0.03 ENSMUST00000118314.8
neurite extension and migration factor
chr17_+_47604995 0.03 ENSMUST00000190020.4
transcriptional regulating factor 1
chr10_+_94350687 0.02 ENSMUST00000065060.12
transmembrane and coiled coil domains 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.3 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.7 6.6 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.7 3.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.4 3.0 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.3 2.9 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.3 2.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 0.6 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.2 3.4 GO:0070307 lens fiber cell development(GO:0070307)
0.2 6.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 4.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 0.9 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 1.0 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.2 2.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 4.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 2.8 GO:0051601 exocyst localization(GO:0051601)
0.2 8.1 GO:0035411 catenin import into nucleus(GO:0035411)
0.2 3.2 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.2 2.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.8 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.5 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 1.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 9.9 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 0.6 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.2 GO:0033189 response to vitamin A(GO:0033189)
0.1 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 2.0 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.8 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 0.6 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 1.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.4 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 1.8 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 2.1 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.6 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 1.0 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 1.2 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.8 GO:0000578 embryonic axis specification(GO:0000578)
0.0 0.3 GO:0046033 AMP metabolic process(GO:0046033)
0.0 1.4 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.9 GO:0051693 actin filament capping(GO:0051693)
0.0 0.7 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 9.9 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.1 3.3 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.4 1.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.4 4.1 GO:0097451 glial limiting end-foot(GO:0097451)
0.3 1.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.2 3.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.2 0.9 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.2 2.0 GO:0001739 sex chromatin(GO:0001739)
0.2 1.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 0.8 GO:0002142 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.1 2.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 3.8 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 2.8 GO:0000145 exocyst(GO:0000145)
0.1 0.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 19.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.0 GO:0000796 condensin complex(GO:0000796)
0.1 6.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 1.1 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 2.0 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 3.0 GO:0005643 nuclear pore(GO:0005643)
0.0 4.5 GO:0005882 intermediate filament(GO:0005882)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 5.5 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 6.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.8 GO:0031672 A band(GO:0031672)
0.0 0.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 4.9 GO:0072562 blood microparticle(GO:0072562)
0.0 3.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 10.4 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.6 5.3 GO:0034711 inhibin binding(GO:0034711)
0.3 1.0 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.3 6.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.3 2.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 1.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 3.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 2.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.6 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 5.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 2.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.6 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 2.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 4.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 9.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.0 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0008430 selenium binding(GO:0008430)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.4 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 4.1 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 2.6 GO:0000149 SNARE binding(GO:0000149)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.0 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 15.3 PID CMYB PATHWAY C-MYB transcription factor network
0.1 4.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 5.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 4.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 3.3 PID PLK1 PATHWAY PLK1 signaling events
0.1 0.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 5.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 5.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 16.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 4.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 6.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.8 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 3.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.0 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S