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GSE58827: Dynamics of the Mouse Liver

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Results for Atf7_E4f1

Z-value: 0.83

Motif logo

Transcription factors associated with Atf7_E4f1

Gene Symbol Gene ID Gene Info
ENSMUSG00000099083.8 activating transcription factor 7
ENSMUSG00000024137.10 E4F transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E4f1mm39_v1_chr17_-_24674252_246743660.334.7e-02Click!
Atf7mm39_v1_chr15_-_102533494_102533535-0.222.1e-01Click!

Activity profile of Atf7_E4f1 motif

Sorted Z-values of Atf7_E4f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_36626101 5.86 ENSMUST00000029270.10
cyclin A2
chr5_+_123214332 4.27 ENSMUST00000067505.15
ENSMUST00000111619.10
ENSMUST00000160344.2
transmembrane protein 120B
chr8_+_117648474 3.60 ENSMUST00000034205.5
ENSMUST00000212775.2
centromere protein N
chr5_+_143534455 3.26 ENSMUST00000169329.8
ENSMUST00000067145.12
ENSMUST00000119488.2
ENSMUST00000118121.2
ENSMUST00000200267.2
ENSMUST00000196487.2
family with sequence similarity 220, member A
family with sequence similarity 220, member A
chr14_-_69522431 3.01 ENSMUST00000183882.2
ENSMUST00000037064.5
solute carrier family 25, member 37
chr11_+_113510135 2.90 ENSMUST00000146390.3
somatostatin receptor 2
chr8_-_86091946 2.79 ENSMUST00000034133.14
myosin light chain kinase 3
chr8_-_86091970 2.77 ENSMUST00000121972.8
myosin light chain kinase 3
chr10_+_75407356 2.72 ENSMUST00000143226.8
ENSMUST00000124259.8
gamma-glutamyltransferase 1
chr7_+_3706992 2.72 ENSMUST00000006496.15
ENSMUST00000108623.8
ENSMUST00000139818.2
ENSMUST00000108625.8
ribosomal protein S9
chr10_-_81214293 2.71 ENSMUST00000140901.8
fizzy and cell division cycle 20 related 1
chr7_+_44117444 2.63 ENSMUST00000206887.2
ENSMUST00000117324.8
ENSMUST00000120852.8
ENSMUST00000134398.3
ENSMUST00000118628.8
Josephin domain containing 2
chr15_+_79231720 2.55 ENSMUST00000096350.11
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr14_-_69740670 2.50 ENSMUST00000180059.3
ENSMUST00000179116.3
predicted gene, 16867
chr15_+_79232137 2.43 ENSMUST00000163691.3
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr15_+_98972850 2.42 ENSMUST00000039665.8
trophinin associated protein
chr7_+_44117511 2.32 ENSMUST00000121922.3
ENSMUST00000208117.2
Josephin domain containing 2
chr3_+_103078971 2.29 ENSMUST00000005830.15
breast carcinoma amplified sequence 2
chr12_-_69205882 2.26 ENSMUST00000037023.9
ribosomal protein S29
chr7_+_44117404 2.20 ENSMUST00000035844.11
Josephin domain containing 2
chr7_+_44117475 2.17 ENSMUST00000118493.8
Josephin domain containing 2
chr6_-_86646118 2.17 ENSMUST00000001184.10
MAX dimerization protein 1
chr3_+_89366425 2.15 ENSMUST00000029564.12
phosphomevalonate kinase
chr4_-_133972890 2.13 ENSMUST00000030644.8
zinc finger protein 593
chr1_+_134383247 2.12 ENSMUST00000112232.8
ENSMUST00000027725.11
ENSMUST00000116528.2
kelch-like 12
chr11_+_22940519 2.12 ENSMUST00000173867.8
chaperonin containing Tcp1, subunit 4 (delta)
chr11_+_113510207 2.06 ENSMUST00000106630.2
somatostatin receptor 2
chr8_-_124675939 2.02 ENSMUST00000044795.8
nucleoporin 133
chr7_-_133304244 1.95 ENSMUST00000209636.2
ENSMUST00000153698.3
uroporphyrinogen III synthase
chr3_+_40754489 1.93 ENSMUST00000203295.3
polo like kinase 4
chr2_-_126975804 1.90 ENSMUST00000110387.4
non-SMC condensin I complex, subunit H
chr2_+_164587901 1.87 ENSMUST00000017443.14
ENSMUST00000109326.10
deoxynucleotidyltransferase, terminal, interacting protein 1
chr4_+_130253925 1.86 ENSMUST00000105994.4
small nuclear ribonucleoprotein 40 (U5)
chr1_-_134006847 1.82 ENSMUST00000020692.7
BTG anti-proliferation factor 2
chr12_+_103354915 1.82 ENSMUST00000101094.9
ENSMUST00000021620.13
OTU domain, ubiquitin aldehyde binding 2
chr11_+_22940599 1.82 ENSMUST00000020562.5
chaperonin containing Tcp1, subunit 4 (delta)
chr16_-_57427179 1.81 ENSMUST00000114371.5
ENSMUST00000232413.2
cms small ribosomal subunit 1
chr18_-_62313019 1.78 ENSMUST00000053640.5
adrenergic receptor, beta 2
chr2_-_132095146 1.77 ENSMUST00000028817.7
proliferating cell nuclear antigen
chr3_-_127346882 1.75 ENSMUST00000197668.2
ENSMUST00000029588.10
La ribonucleoprotein domain family, member 7
chr12_+_112611322 1.75 ENSMUST00000109755.5
SIVA1, apoptosis-inducing factor
chr2_+_164587948 1.74 ENSMUST00000109327.4
deoxynucleotidyltransferase, terminal, interacting protein 1
chr11_-_78056347 1.73 ENSMUST00000017530.4
TNF receptor associated factor 4
chr7_-_141649003 1.73 ENSMUST00000039926.10
dual specificity phosphatase 8
chr7_+_97437709 1.67 ENSMUST00000206984.2
p21 (RAC1) activated kinase 1
chr12_+_112611069 1.66 ENSMUST00000021728.12
SIVA1, apoptosis-inducing factor
chr3_+_134918298 1.66 ENSMUST00000062893.12
centromere protein E
chr17_-_71833752 1.61 ENSMUST00000232863.2
ENSMUST00000024851.10
NDC80 kinetochore complex component
chr7_+_141027763 1.61 ENSMUST00000106003.2
ribosomal protein, large P2
chr6_-_49240944 1.60 ENSMUST00000204189.3
ENSMUST00000031841.9
transformer 2 alpha
chr10_-_17823736 1.57 ENSMUST00000037879.8
hdc homolog, cell cycle regulator
chr9_-_96360676 1.54 ENSMUST00000057500.6
ring finger protein 7
chr7_+_102090892 1.46 ENSMUST00000033283.10
ribonucleotide reductase M1
chr5_+_33978035 1.46 ENSMUST00000075812.11
ENSMUST00000114397.9
ENSMUST00000155880.8
nuclear receptor binding SET domain protein 2
chr12_+_4132567 1.39 ENSMUST00000020986.15
ENSMUST00000049584.6
DnaJ heat shock protein family (Hsp40) member C27
chr7_+_141027557 1.36 ENSMUST00000106004.8
ribosomal protein, large P2
chr14_-_87378641 1.36 ENSMUST00000168889.3
ENSMUST00000022599.14
diaphanous related formin 3
chr13_+_75855695 1.31 ENSMUST00000222194.2
ENSMUST00000223535.2
ENSMUST00000222853.2
elongation factor for RNA polymerase II 2
chr13_+_22227359 1.29 ENSMUST00000110452.2
H2B clustered histone 11
chr4_-_131802561 1.28 ENSMUST00000105970.8
ENSMUST00000105975.8
erythrocyte membrane protein band 4.1
chr10_-_30076543 1.25 ENSMUST00000099985.6
centromere protein W
chr9_+_20799471 1.25 ENSMUST00000004203.6
peter pan homolog
chrX_-_8011952 1.25 ENSMUST00000115615.9
ENSMUST00000115616.8
ENSMUST00000115621.9
RNA binding motif (RNP1, RRM) protein 3
chr6_-_30304512 1.25 ENSMUST00000094543.3
ENSMUST00000102993.10
ubiquitin-conjugating enzyme E2H
chr3_+_89366632 1.23 ENSMUST00000107410.8
phosphomevalonate kinase
chr4_-_117013396 1.22 ENSMUST00000102696.5
ribosomal protein S8
chr8_-_85567256 1.21 ENSMUST00000003911.13
ENSMUST00000109761.9
ENSMUST00000128035.2
RAD23 homolog A, nucleotide excision repair protein
chr17_-_37269425 1.20 ENSMUST00000172518.8
RNA polymerase I subunit H
chr9_-_96360648 1.20 ENSMUST00000071301.5
ring finger protein 7
chr5_-_110801213 1.19 ENSMUST00000042147.6
NOC4 like
chr11_-_97673203 1.19 ENSMUST00000128801.2
ENSMUST00000103146.5
ribosomal protein L23
chr11_-_40624200 1.18 ENSMUST00000020579.9
hyaluronan mediated motility receptor (RHAMM)
chr7_+_45367479 1.16 ENSMUST00000072503.13
ENSMUST00000211061.2
ENSMUST00000209693.2
ribosomal protein L18
chr10_-_111833138 1.15 ENSMUST00000074805.12
GLI pathogenesis-related 1 (glioma)
chr15_+_79975520 1.14 ENSMUST00000009728.13
ENSMUST00000009727.12
synaptogyrin 1
chr7_+_45367545 1.14 ENSMUST00000209287.2
ribosomal protein L18
chrX_-_8011918 1.11 ENSMUST00000115619.8
ENSMUST00000115617.10
ENSMUST00000040010.10
RNA binding motif (RNP1, RRM) protein 3
chr17_-_37269330 1.09 ENSMUST00000113669.9
RNA polymerase I subunit H
chr6_-_25809209 1.09 ENSMUST00000115330.8
protection of telomeres 1A
chr17_+_32255071 1.09 ENSMUST00000081339.13
ribosomal RNA processing 1B
chr7_-_30364394 1.08 ENSMUST00000019697.9
HAUS augmin-like complex, subunit 5
chrX_+_134894573 1.06 ENSMUST00000058119.9
adipocyte-related X-chromosome expressed sequence 2
chr15_-_38519499 1.05 ENSMUST00000110329.8
ENSMUST00000065308.13
antizyme inhibitor 1
chr8_+_67312847 1.03 ENSMUST00000118009.2
nuclear assembly factor 1 ribonucleoprotein
chr9_+_54606144 1.03 ENSMUST00000120452.8
DnaJ heat shock protein family (Hsp40) member A4
chr1_-_75455915 1.02 ENSMUST00000079205.14
ENSMUST00000094818.4
chondroitin polymerizing factor
chr8_-_26087475 1.02 ENSMUST00000210810.2
ENSMUST00000210616.2
ENSMUST00000079160.8
leucine zipper-EF-hand containing transmembrane protein 2
chr4_-_131802606 1.01 ENSMUST00000146021.8
erythrocyte membrane protein band 4.1
chr5_+_33176160 0.98 ENSMUST00000019109.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr8_+_123829089 0.98 ENSMUST00000000756.6
ribosomal protein L13
chr17_-_34043502 0.97 ENSMUST00000087342.13
ENSMUST00000173844.8
ribosomal protein S28
chr16_+_49519561 0.96 ENSMUST00000046777.11
ENSMUST00000142682.9
intraflagellar transport 57
chr7_+_30113170 0.95 ENSMUST00000207982.2
ENSMUST00000032800.10
TYRO protein tyrosine kinase binding protein
chr13_-_21937997 0.95 ENSMUST00000074752.4
H2A clustered histone 15
chr6_-_131270136 0.94 ENSMUST00000032307.12
mago homolog B, exon junction complex core component
chr2_+_109111083 0.94 ENSMUST00000028527.8
kinesin family member 18A
chr12_+_73333641 0.92 ENSMUST00000153941.8
ENSMUST00000122920.8
ENSMUST00000101313.4
solute carrier family 38, member 6
chr17_+_26882171 0.91 ENSMUST00000236346.2
ATPase, H+ transporting, lysosomal V0 subunit E
chr17_-_34043320 0.91 ENSMUST00000173879.8
ENSMUST00000166693.3
ENSMUST00000173019.8
ribosomal protein S28
chr11_+_69805005 0.90 ENSMUST00000057884.6
G protein pathway suppressor 2
chr17_-_26727437 0.87 ENSMUST00000236661.2
ENSMUST00000025025.7
dual specificity phosphatase 1
chr3_+_40754448 0.87 ENSMUST00000026858.11
polo like kinase 4
chr2_-_156848923 0.86 ENSMUST00000146413.8
ENSMUST00000103129.9
ENSMUST00000103130.8
DSN1 homolog, MIS12 kinetochore complex component
chr7_-_105393519 0.86 ENSMUST00000141116.2
TATA-box binding protein associated factor 10
chr14_-_67309866 0.86 ENSMUST00000225380.2
ENSMUST00000089230.7
protein phosphatase 2, regulatory subunit B, alpha
chr13_+_8935537 0.84 ENSMUST00000169314.9
isopentenyl-diphosphate delta isomerase
chr7_-_44635813 0.84 ENSMUST00000208829.2
ENSMUST00000207370.2
ENSMUST00000107843.11
protein arginine N-methyltransferase 1
chr6_+_113508636 0.83 ENSMUST00000036340.12
ENSMUST00000204827.3
Fanconi anemia, complementation group D2
chr19_-_5962798 0.82 ENSMUST00000118623.2
D4, zinc and double PHD fingers family 2
chr1_+_59724108 0.82 ENSMUST00000027174.10
ENSMUST00000190231.7
ENSMUST00000191142.7
ENSMUST00000185772.7
NOP58 ribonucleoprotein
chr13_-_9046020 0.82 ENSMUST00000222098.2
GTP binding protein 4
chr19_-_24938909 0.81 ENSMUST00000025815.10
COBW domain containing 1
chr12_+_108572015 0.81 ENSMUST00000109854.9
Ena-vasodilator stimulated phosphoprotein
chr10_-_128361731 0.81 ENSMUST00000026427.8
extended synaptotagmin-like protein 1
chr7_-_44635740 0.81 ENSMUST00000209056.3
ENSMUST00000209124.2
ENSMUST00000208312.2
ENSMUST00000207659.2
ENSMUST00000045325.14
protein arginine N-methyltransferase 1
chr14_+_47710005 0.80 ENSMUST00000043112.9
ENSMUST00000163324.8
ENSMUST00000228668.2
ENSMUST00000168833.9
F-box protein 34
chr8_+_75836187 0.79 ENSMUST00000164309.3
ENSMUST00000212426.2
ENSMUST00000212811.2
minichromosome maintenance complex component 5
chr5_+_101912939 0.76 ENSMUST00000031273.9
CDP-diacylglycerol synthase 1
chr11_-_86999481 0.75 ENSMUST00000051395.9
proline rich 11
chr14_+_47710085 0.75 ENSMUST00000095941.9
F-box protein 34
chr18_+_82932747 0.74 ENSMUST00000071233.7
zinc finger protein 516
chr13_-_100881117 0.74 ENSMUST00000078573.5
ENSMUST00000109333.8
mitochondrial ribosomal protein S36
chr12_+_102710008 0.74 ENSMUST00000057416.8
transmembrane protein 251
chr11_+_68792364 0.73 ENSMUST00000073471.13
ENSMUST00000101014.9
ENSMUST00000128952.8
ENSMUST00000167436.3
ribosomal protein L26
chr5_+_114582327 0.73 ENSMUST00000137167.8
ENSMUST00000112239.9
ENSMUST00000124260.8
ENSMUST00000125650.6
ENSMUST00000043760.15
mevalonate kinase
chr8_-_4375320 0.73 ENSMUST00000098950.6
ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
chr1_+_175708341 0.71 ENSMUST00000195196.6
ENSMUST00000194306.6
ENSMUST00000193822.6
exonuclease 1
chr7_+_127503251 0.71 ENSMUST00000071056.14
branched chain ketoacid dehydrogenase kinase
chr16_-_31984272 0.70 ENSMUST00000231836.2
ENSMUST00000115163.4
ENSMUST00000144345.2
ENSMUST00000143682.8
ENSMUST00000115165.10
ENSMUST00000099991.11
ENSMUST00000130410.8
negative regulator of reactive oxygen species
chr13_+_38220971 0.70 ENSMUST00000021866.10
RIO kinase 1
chr8_+_71151581 0.69 ENSMUST00000095267.8
jun D proto-oncogene
chr16_+_21828223 0.69 ENSMUST00000023561.8
SUMO/sentrin specific peptidase 2
chr8_-_23143422 0.69 ENSMUST00000033938.7
polymerase (DNA directed), beta
chr5_+_24369961 0.69 ENSMUST00000049887.13
nucleoporin like 2
chr10_-_128383508 0.68 ENSMUST00000152539.8
ENSMUST00000133458.2
ENSMUST00000040572.10
zinc finger CCCH type containing 10
chr8_-_81466126 0.68 ENSMUST00000043359.9
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr2_-_163486998 0.68 ENSMUST00000017851.4
serine incorporator 3
chr14_-_30741012 0.68 ENSMUST00000037739.8
guanine nucleotide binding protein-like 3 (nucleolar)
chr17_-_37269153 0.67 ENSMUST00000172823.2
RNA polymerase I subunit H
chr11_-_88608920 0.67 ENSMUST00000092794.12
musashi RNA-binding protein 2
chr9_-_59393893 0.66 ENSMUST00000171975.8
ariadne RBR E3 ubiquitin protein ligase 1
chr15_+_43340609 0.66 ENSMUST00000022962.8
ER membrane protein complex subunit 2
chr10_+_72490705 0.65 ENSMUST00000105431.8
ENSMUST00000160337.2
ZW10 interactor
chr13_+_120151982 0.65 ENSMUST00000179869.3
ENSMUST00000224188.2
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
chr11_+_87000032 0.65 ENSMUST00000020794.6
spindle and kinetochore associated complex subunit 2
chr17_-_35055843 0.64 ENSMUST00000077477.12
serine/threonine kinase 19
chr10_-_78248771 0.64 ENSMUST00000062678.11
ribosomal RNA processing 1
chr5_-_130284366 0.63 ENSMUST00000026387.11
SBDS ribosome maturation factor
chr12_+_79177523 0.62 ENSMUST00000021550.7
arginase type II
chr18_+_11790409 0.62 ENSMUST00000047322.8
retinoblastoma binding protein 8, endonuclease
chr11_-_70128678 0.61 ENSMUST00000108575.9
RIKEN cDNA 0610010K14 gene
chr10_+_72490677 0.61 ENSMUST00000020081.11
ZW10 interactor
chr6_+_54658609 0.61 ENSMUST00000190641.7
ENSMUST00000187701.2
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr2_-_132420074 0.60 ENSMUST00000110136.8
ENSMUST00000124107.8
ENSMUST00000060955.12
glycerophosphocholine phosphodiesterase 1
chr11_+_59099147 0.60 ENSMUST00000020719.7
RIKEN cDNA 2310033P09 gene
chr7_-_103778992 0.59 ENSMUST00000053743.6
ubiquilin 5
chr2_-_124965537 0.59 ENSMUST00000142718.8
ENSMUST00000152367.8
ENSMUST00000067780.10
ENSMUST00000147105.8
myelin basic protein expression factor 2, repressor
chr13_-_96807346 0.59 ENSMUST00000022176.15
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
chr6_-_25809188 0.59 ENSMUST00000115327.8
protection of telomeres 1A
chr19_-_4675352 0.58 ENSMUST00000224707.2
ENSMUST00000237059.2
Ras converting CAAX endopeptidase 1
chr5_-_38719025 0.58 ENSMUST00000005234.13
WD repeat domain 1
chr11_-_101442663 0.58 ENSMUST00000017290.11
breast cancer 1, early onset
chr11_+_100211363 0.58 ENSMUST00000152521.2
eukaryotic translation initiation factor 1
chr13_+_21938258 0.58 ENSMUST00000091709.3
H2B clustered histone 15
chr11_-_69563133 0.57 ENSMUST00000163666.3
eukaryotic translation initiation factor 4A1
chr4_-_46138397 0.57 ENSMUST00000144495.2
ENSMUST00000107770.2
ENSMUST00000156021.2
ENSMUST00000107772.8
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr19_-_61215743 0.56 ENSMUST00000237386.2
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr11_-_59054521 0.56 ENSMUST00000137433.2
ENSMUST00000054523.6
IBA57 homolog, iron-sulfur cluster assembly
chr15_-_79571977 0.55 ENSMUST00000023061.7
Josephin domain containing 1
chr9_+_64718708 0.55 ENSMUST00000213926.2
DENN/MADD domain containing 4A
chr11_+_76134541 0.55 ENSMUST00000040577.5
mitochondrial rRNA methyltransferase 3
chr1_+_75145275 0.55 ENSMUST00000162768.8
ENSMUST00000160439.8
ENSMUST00000027394.12
zinc finger, AN1 type domain 2B
chr5_+_137628377 0.55 ENSMUST00000175968.8
leucine-rich repeats and calponin homology (CH) domain containing 4
chr16_+_21613068 0.54 ENSMUST00000211443.2
ENSMUST00000231300.2
ENSMUST00000209449.2
ENSMUST00000181780.9
ENSMUST00000209728.2
ENSMUST00000181960.3
ENSMUST00000209429.2
ENSMUST00000180830.3
ENSMUST00000231988.2
RIKEN cDNA 1300002E11 gene
mitogen-activated protein kinase kinase kinase 13
chr7_+_44397837 0.54 ENSMUST00000002275.15
vaccinia related kinase 3
chr17_-_28126679 0.53 ENSMUST00000025057.5
TATA-box binding protein associated factor 11
chr11_-_70128712 0.53 ENSMUST00000108577.8
ENSMUST00000108579.8
ENSMUST00000021181.13
ENSMUST00000108578.9
ENSMUST00000102569.10
RIKEN cDNA 0610010K14 gene
chr2_+_120439858 0.53 ENSMUST00000124187.8
HAUS augmin-like complex, subunit 2
chr9_+_20914012 0.52 ENSMUST00000003386.7
mitochondrial ribosomal protein L4
chr7_+_30411634 0.52 ENSMUST00000005692.14
ENSMUST00000170371.2
ATPase, H+/K+ exchanging, gastric, alpha polypeptide
chr1_-_165064455 0.52 ENSMUST00000043235.8
TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
chr19_+_36903471 0.51 ENSMUST00000099494.4
B-TFIID TATA-box binding protein associated factor 1
chr17_-_57318271 0.51 ENSMUST00000002733.7
general transcription factor IIF, polypeptide 1
chr11_+_110858842 0.51 ENSMUST00000180023.8
ENSMUST00000106636.8
potassium inwardly-rectifying channel, subfamily J, member 16
chr14_+_51045298 0.51 ENSMUST00000036126.7
poly (ADP-ribose) polymerase family, member 2
chr11_+_68582731 0.51 ENSMUST00000102611.10
myosin, heavy polypeptide 10, non-muscle
chr4_+_46138576 0.51 ENSMUST00000030014.9
nuclear cap binding protein subunit 1
chr1_-_191307648 0.50 ENSMUST00000027933.11
denticleless E3 ubiquitin protein ligase
chr19_-_61216834 0.49 ENSMUST00000076046.7
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr4_-_151142351 0.49 ENSMUST00000030797.4
vesicle-associated membrane protein 3
chr2_-_36026614 0.49 ENSMUST00000122456.8
RNA binding motif protein 18
chr17_+_35201130 0.49 ENSMUST00000173004.2
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr9_+_20914211 0.48 ENSMUST00000214124.2
ENSMUST00000216818.2
mitochondrial ribosomal protein L4
chr5_+_150446064 0.48 ENSMUST00000044620.11
ENSMUST00000202003.4
breast cancer 2, early onset
chr10_-_128329693 0.48 ENSMUST00000217776.2
ENSMUST00000219236.2
ENSMUST00000217733.2
ENSMUST00000218127.2
ENSMUST00000217969.2
ENSMUST00000164181.2
myosin, light polypeptide 6, alkali, smooth muscle and non-muscle
chr15_-_51728893 0.48 ENSMUST00000022925.10
eukaryotic translation initiation factor 3, subunit H
chr7_+_90091937 0.47 ENSMUST00000061767.5
CREB/ATF bZIP transcription factor
chr7_-_101859379 0.47 ENSMUST00000210682.2
nucleoporin 98
chr10_+_79518002 0.47 ENSMUST00000020550.13
cell division cycle 34
chr3_+_127347099 0.46 ENSMUST00000043108.9
ENSMUST00000196141.5
ENSMUST00000195955.2
zinc finger, GRF-type containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Atf7_E4f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.9 5.6 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.6 1.9 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.5 3.9 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.5 1.9 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.5 1.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.4 1.8 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.4 1.8 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.4 1.7 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.4 1.7 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.4 1.5 GO:0003290 atrial septum secundum morphogenesis(GO:0003290)
0.4 1.4 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.4 2.8 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.3 2.7 GO:1901748 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.3 2.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.3 1.6 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.3 1.0 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.3 1.3 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.3 5.0 GO:0030432 peristalsis(GO:0030432)
0.3 1.2 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.3 1.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.3 2.0 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.3 1.0 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.3 0.8 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845) negative regulation of histone phosphorylation(GO:0033128)
0.3 3.6 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 1.2 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.2 2.9 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.2 2.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.2 3.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.2 0.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 1.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 3.3 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.2 2.3 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.2 0.7 GO:1902164 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 0.5 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.2 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.2 0.5 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.2 0.6 GO:0010958 regulation of amino acid import(GO:0010958)
0.2 0.8 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 5.1 GO:0034508 centromere complex assembly(GO:0034508)
0.1 0.4 GO:2000847 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 1.3 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 2.7 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.7 GO:0009597 detection of virus(GO:0009597)
0.1 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 1.9 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.5 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 2.3 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 1.3 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 1.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.4 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.1 0.8 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.9 GO:0007000 nucleolus organization(GO:0007000)
0.1 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.4 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.1 5.7 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 1.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 2.5 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.1 1.1 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.1 0.5 GO:0021763 subthalamic nucleus development(GO:0021763) superior vena cava morphogenesis(GO:0060578)
0.1 0.3 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.1 0.2 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
0.1 0.7 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.6 GO:0048539 bone marrow development(GO:0048539)
0.1 1.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 1.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.5 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.2 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.1 0.2 GO:0051385 response to mineralocorticoid(GO:0051385)
0.1 0.2 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.1 0.2 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 4.5 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 0.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.9 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 0.2 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.1 1.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 1.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.3 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.9 GO:0070365 hepatocyte differentiation(GO:0070365)
0.1 0.2 GO:0021764 amygdala development(GO:0021764)
0.1 0.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 3.8 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.3 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 3.1 GO:0009409 response to cold(GO:0009409)
0.1 3.0 GO:0006414 translational elongation(GO:0006414)
0.1 1.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 0.2 GO:1990173 protein localization to nucleoplasm(GO:1990173)
0.1 0.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.2 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.2 GO:0002191 formation of cytoplasmic translation initiation complex(GO:0001732) cap-dependent translational initiation(GO:0002191)
0.1 0.5 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.6 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.5 GO:0030035 microspike assembly(GO:0030035)
0.1 0.7 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 1.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.7 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.8 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 6.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.9 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.1 GO:0032202 telomere assembly(GO:0032202)
0.0 0.2 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.0 0.2 GO:0035617 stress granule disassembly(GO:0035617)
0.0 1.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 1.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 1.0 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.8 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.2 GO:0060702 regulation of endoribonuclease activity(GO:0060699) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.0 0.5 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.5 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.2 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 3.9 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 0.1 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.2 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.9 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.9 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.4 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.7 GO:0002076 osteoblast development(GO:0002076)
0.0 0.2 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.3 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.5 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.5 GO:0030049 muscle filament sliding(GO:0030049)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.6 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 1.1 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 2.6 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.0 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.0 0.0 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 0.3 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.3 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 1.3 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:0006379 mRNA cleavage(GO:0006379)
0.0 3.6 GO:0045444 fat cell differentiation(GO:0045444)
0.0 1.5 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343) motor behavior(GO:0061744)
0.0 4.6 GO:0008380 RNA splicing(GO:0008380)
0.0 0.0 GO:0061187 histone H4-K20 demethylation(GO:0035574) regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0046878 angiotensin-mediated drinking behavior(GO:0003051) positive regulation of saliva secretion(GO:0046878)
0.0 0.4 GO:0046329 negative regulation of JNK cascade(GO:0046329)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.5 2.7 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.5 5.9 GO:0001940 male pronucleus(GO:0001940)
0.4 1.6 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.4 2.8 GO:0098536 deuterosome(GO:0098536)
0.4 4.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.4 1.9 GO:0000799 nuclear condensin complex(GO:0000799)
0.3 0.9 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.3 3.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 1.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 1.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 3.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 0.6 GO:0042643 actomyosin, actin portion(GO:0042643)
0.2 1.8 GO:0070187 telosome(GO:0070187)
0.2 1.6 GO:0070652 HAUS complex(GO:0070652)
0.2 0.9 GO:0000125 PCAF complex(GO:0000125)
0.2 2.9 GO:0000974 Prp19 complex(GO:0000974)
0.2 2.2 GO:0016589 NURF complex(GO:0016589)
0.1 0.7 GO:0035976 AP1 complex(GO:0035976)
0.1 8.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.6 GO:0034709 methylosome(GO:0034709)
0.1 0.9 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 2.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 8.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 2.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 3.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.8 GO:0033503 HULC complex(GO:0033503)
0.1 1.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.5 GO:0044393 microspike(GO:0044393)
0.1 0.8 GO:0070761 box C/D snoRNP complex(GO:0031428) pre-snoRNP complex(GO:0070761)
0.1 1.0 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 4.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.7 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 1.9 GO:0005682 U5 snRNP(GO:0005682)
0.1 2.0 GO:0030686 90S preribosome(GO:0030686)
0.1 1.7 GO:0071437 invadopodium(GO:0071437)
0.1 0.5 GO:0097513 myosin II filament(GO:0097513)
0.1 1.0 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 1.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.0 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 6.8 GO:0000776 kinetochore(GO:0000776)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 1.0 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.6 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 3.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 2.0 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0002095 caveolar macromolecular signaling complex(GO:0002095)
0.0 1.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.7 GO:0099738 cell cortex region(GO:0099738)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.2 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 1.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.8 GO:0090544 BAF-type complex(GO:0090544)
0.0 1.2 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 3.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.5 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0097677 STAT family protein binding(GO:0097677)
0.8 5.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.7 2.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.6 5.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.6 1.8 GO:0030337 DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
0.6 1.7 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.5 4.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.5 2.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.4 1.8 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.4 1.6 GO:0030519 snoRNP binding(GO:0030519)
0.4 1.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.4 1.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.3 1.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.3 1.9 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.3 0.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 1.9 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.3 1.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.3 1.8 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.3 0.8 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 2.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 1.0 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 1.2 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.2 1.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 0.7 GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.2 1.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 1.7 GO:0043515 kinetochore binding(GO:0043515)
0.2 2.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 0.6 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 0.5 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.2 2.7 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 0.5 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.2 0.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.7 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 0.4 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 3.5 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 6.2 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 1.5 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.3 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 3.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.8 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 2.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 7.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 12.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.0 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 1.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 4.3 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.0 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 1.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 2.1 GO:0019843 rRNA binding(GO:0019843)
0.1 3.4 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.1 0.7 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.5 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.5 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 2.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.9 GO:0048156 tau protein binding(GO:0048156)
0.0 1.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0008821 recombinase activity(GO:0000150) crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.3 GO:0043022 ribosome binding(GO:0043022)
0.0 1.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 4.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.4 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 1.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.9 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 1.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.0 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 2.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 3.9 PID BARD1 PATHWAY BARD1 signaling events
0.1 6.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 2.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.9 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 0.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.5 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.9 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 6.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 4.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 8.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.0 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 8.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 3.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 1.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 3.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 0.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 2.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 4.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.9 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.6 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 3.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 3.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins