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GSE58827: Dynamics of the Mouse Liver

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Results for Atoh1_Bhlhe23

Z-value: 0.41

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Transcription factors associated with Atoh1_Bhlhe23

Gene Symbol Gene ID Gene Info
Atoh1
ENSMUSG00000073043.6 atonal bHLH transcription factor 1
Bhlhe23
ENSMUSG00000045493.5 basic helix-loop-helix family, member e23

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Atoh1mm39_v1_chr6_+_64706101_647061170.192.7e-01Click!

Activity profile of Atoh1_Bhlhe23 motif

Sorted Z-values of Atoh1_Bhlhe23 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_70945434 3.43 ENSMUST00000228346.2
Xpo7
exportin 7
chr7_+_127503812 3.26 ENSMUST00000151451.3
ENSMUST00000124533.3
ENSMUST00000206745.2
ENSMUST00000206140.2
Bckdk
branched chain ketoacid dehydrogenase kinase
chr14_+_43951187 2.55 ENSMUST00000094051.6
Gm7324
predicted gene 7324
chr7_-_126303947 2.37 ENSMUST00000032949.14
Coro1a
coronin, actin binding protein 1A
chrX_+_55500170 1.96 ENSMUST00000039374.9
ENSMUST00000101553.9
ENSMUST00000186445.7
Ints6l
integrator complex subunit 6 like
chr8_-_107792264 1.94 ENSMUST00000034393.7
Tmed6
transmembrane p24 trafficking protein 6
chr7_-_126303887 1.81 ENSMUST00000131415.8
Coro1a
coronin, actin binding protein 1A
chr10_-_128237087 1.77 ENSMUST00000042666.13
Slc39a5
solute carrier family 39 (metal ion transporter), member 5
chr10_-_128236317 1.76 ENSMUST00000167859.2
ENSMUST00000218858.2
Slc39a5
solute carrier family 39 (metal ion transporter), member 5
chr7_-_126736979 1.76 ENSMUST00000049931.6
Spn
sialophorin
chr9_-_21829385 1.73 ENSMUST00000128442.2
ENSMUST00000119055.8
ENSMUST00000122211.8
ENSMUST00000115351.10
Rab3d
RAB3D, member RAS oncogene family
chr11_-_69493567 1.67 ENSMUST00000138694.2
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr10_-_128236366 1.58 ENSMUST00000219131.2
Slc39a5
solute carrier family 39 (metal ion transporter), member 5
chr9_+_56344700 1.57 ENSMUST00000239472.2
ENSMUSG00000118653.2
ubiquitin-conjugating enzyme E2S (Ube2s) retrogene
chr11_-_97673203 1.26 ENSMUST00000128801.2
ENSMUST00000103146.5
Rpl23
ribosomal protein L23
chrX_+_70599524 1.26 ENSMUST00000072699.13
ENSMUST00000114582.9
ENSMUST00000015361.11
ENSMUST00000088874.10
Hmgb3
high mobility group box 3
chr7_-_126303689 1.25 ENSMUST00000135087.8
Coro1a
coronin, actin binding protein 1A
chr19_-_46033353 1.15 ENSMUST00000026252.14
ENSMUST00000156585.9
ENSMUST00000185355.7
ENSMUST00000152946.8
Ldb1
LIM domain binding 1
chr3_-_126792056 1.15 ENSMUST00000044443.15
Ank2
ankyrin 2, brain
chr19_-_53577499 1.13 ENSMUST00000095978.5
Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr9_-_71803354 0.98 ENSMUST00000184448.8
Tcf12
transcription factor 12
chr3_+_87814147 0.94 ENSMUST00000159492.8
Hdgf
heparin binding growth factor
chr11_+_58845502 0.93 ENSMUST00000108817.5
ENSMUST00000047697.12
H2aw
Trim17
H2A.W histone
tripartite motif-containing 17
chr11_-_72441054 0.89 ENSMUST00000021154.7
Spns3
spinster homolog 3
chr7_+_127503251 0.86 ENSMUST00000071056.14
Bckdk
branched chain ketoacid dehydrogenase kinase
chr10_-_25076008 0.85 ENSMUST00000100012.3
Akap7
A kinase (PRKA) anchor protein 7
chr11_+_31822211 0.78 ENSMUST00000020543.13
ENSMUST00000109412.9
Cpeb4
cytoplasmic polyadenylation element binding protein 4
chr3_+_3573084 0.77 ENSMUST00000108393.8
Hnf4g
hepatocyte nuclear factor 4, gamma
chr7_+_28488380 0.77 ENSMUST00000209035.2
ENSMUST00000059857.8
Rinl
Ras and Rab interactor-like
chr6_-_119925387 0.76 ENSMUST00000162541.8
Wnk1
WNK lysine deficient protein kinase 1
chr16_+_57173456 0.75 ENSMUST00000159816.8
Filip1l
filamin A interacting protein 1-like
chr5_+_3393893 0.73 ENSMUST00000165117.8
ENSMUST00000197385.2
Cdk6
cyclin-dependent kinase 6
chr2_-_174188505 0.72 ENSMUST00000168292.2
Gm20721
predicted gene, 20721
chr9_+_106158212 0.69 ENSMUST00000072206.14
Poc1a
POC1 centriolar protein A
chr1_-_182929025 0.67 ENSMUST00000171366.7
Disp1
dispatched RND transporter family member 1
chr15_-_91075933 0.61 ENSMUST00000069511.8
Abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chrX_+_158491589 0.60 ENSMUST00000080394.13
Sh3kbp1
SH3-domain kinase binding protein 1
chr13_+_37529184 0.59 ENSMUST00000021860.7
Ly86
lymphocyte antigen 86
chr1_+_150268544 0.59 ENSMUST00000124973.9
Tpr
translocated promoter region, nuclear basket protein
chr19_+_37184927 0.58 ENSMUST00000024078.15
ENSMUST00000112391.8
Marchf5
membrane associated ring-CH-type finger 5
chr5_-_74229021 0.57 ENSMUST00000119154.8
ENSMUST00000068058.14
Usp46
ubiquitin specific peptidase 46
chr19_-_37153436 0.56 ENSMUST00000142973.2
ENSMUST00000154376.8
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr2_+_173918715 0.55 ENSMUST00000087908.10
ENSMUST00000044638.13
ENSMUST00000156054.2
Stx16
syntaxin 16
chr18_+_34892599 0.55 ENSMUST00000097622.4
Fam53c
family with sequence similarity 53, member C
chr19_-_53360197 0.52 ENSMUST00000086887.2
Gm10197
predicted gene 10197
chr6_+_5390386 0.52 ENSMUST00000183358.2
Asb4
ankyrin repeat and SOCS box-containing 4
chr15_+_84553801 0.51 ENSMUST00000171460.8
Prr5
proline rich 5 (renal)
chr11_+_120123727 0.49 ENSMUST00000122148.8
ENSMUST00000044985.14
Bahcc1
BAH domain and coiled-coil containing 1
chr11_-_69811347 0.49 ENSMUST00000108610.8
Eif5a
eukaryotic translation initiation factor 5A
chr11_-_115494692 0.48 ENSMUST00000125097.2
ENSMUST00000019135.14
ENSMUST00000106508.10
Gga3
golgi associated, gamma adaptin ear containing, ARF binding protein 3
chr11_+_100211363 0.45 ENSMUST00000152521.2
Eif1
eukaryotic translation initiation factor 1
chr11_-_87295292 0.45 ENSMUST00000067692.13
Rad51c
RAD51 paralog C
chr3_-_59127571 0.44 ENSMUST00000199675.2
ENSMUST00000170388.6
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr11_-_101308441 0.42 ENSMUST00000070395.9
Aarsd1
alanyl-tRNA synthetase domain containing 1
chr1_+_177272215 0.42 ENSMUST00000192851.2
ENSMUST00000193480.2
ENSMUST00000195388.2
Zbtb18
zinc finger and BTB domain containing 18
chr1_-_170133901 0.41 ENSMUST00000179801.3
Gm7694
predicted gene 7694
chr5_-_90487583 0.41 ENSMUST00000197021.2
Ankrd17
ankyrin repeat domain 17
chr3_-_95902949 0.40 ENSMUST00000123006.8
ENSMUST00000130043.8
Plekho1
pleckstrin homology domain containing, family O member 1
chr13_+_108182941 0.39 ENSMUST00000224361.2
ENSMUST00000224390.2
Smim15
small integral membrane protein 15
chrX_+_35592006 0.38 ENSMUST00000016383.10
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr3_-_129834788 0.38 ENSMUST00000168644.3
Sec24b
Sec24 related gene family, member B (S. cerevisiae)
chr11_+_95734028 0.36 ENSMUST00000107709.8
Gngt2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr9_+_111011327 0.33 ENSMUST00000216430.2
Lrrfip2
leucine rich repeat (in FLII) interacting protein 2
chr2_-_71198091 0.32 ENSMUST00000151937.8
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr17_-_47143214 0.32 ENSMUST00000233537.2
Bicral
BRD4 interacting chromatin remodeling complex associated protein like
chr5_+_75312939 0.31 ENSMUST00000202681.4
ENSMUST00000000476.15
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr9_+_111011388 0.31 ENSMUST00000217117.2
Lrrfip2
leucine rich repeat (in FLII) interacting protein 2
chr16_+_57173632 0.30 ENSMUST00000099667.3
Filip1l
filamin A interacting protein 1-like
chr10_+_70040504 0.28 ENSMUST00000190199.2
Mrln
myoregulin
chr12_-_114901026 0.27 ENSMUST00000103516.2
ENSMUST00000191868.2
Ighv1-42
immunoglobulin heavy variable V1-42
chr11_+_95734419 0.27 ENSMUST00000107708.2
Gngt2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr10_+_70040483 0.26 ENSMUST00000020090.8
Mrln
myoregulin
chr7_+_4928784 0.26 ENSMUST00000057612.9
Ssc5d
scavenger receptor cysteine rich family, 5 domains
chr5_-_120887864 0.26 ENSMUST00000053909.13
ENSMUST00000081491.13
Oas2
2'-5' oligoadenylate synthetase 2
chr11_+_68393845 0.24 ENSMUST00000102613.8
ENSMUST00000060441.7
Pik3r6
phosphoinositide-3-kinase regulatory subunit 5
chr9_+_19620729 0.23 ENSMUST00000217450.4
ENSMUST00000212013.4
Olfr857
olfactory receptor 857
chr6_-_128252540 0.22 ENSMUST00000130454.8
Tead4
TEA domain family member 4
chr15_+_101071948 0.21 ENSMUST00000000544.12
Acvr1b
activin A receptor, type 1B
chr7_+_30399208 0.21 ENSMUST00000013227.8
2200002J24Rik
RIKEN cDNA 2200002J24 gene
chr5_-_124325213 0.20 ENSMUST00000161938.8
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr17_-_48189815 0.20 ENSMUST00000154108.2
Foxp4
forkhead box P4
chr9_+_19716202 0.19 ENSMUST00000212540.3
ENSMUST00000217280.2
Olfr859
olfactory receptor 859
chr6_-_12749192 0.19 ENSMUST00000172356.8
Thsd7a
thrombospondin, type I, domain containing 7A
chr8_+_26092252 0.19 ENSMUST00000136107.9
ENSMUST00000146919.8
ENSMUST00000139966.8
ENSMUST00000142395.8
ENSMUST00000143445.2
Nsd3
nuclear receptor binding SET domain protein 3
chr5_+_123648523 0.17 ENSMUST00000031384.6
B3gnt4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr1_+_177273226 0.17 ENSMUST00000077225.8
Zbtb18
zinc finger and BTB domain containing 18
chr4_-_82768958 0.16 ENSMUST00000139401.2
Zdhhc21
zinc finger, DHHC domain containing 21
chr17_-_87255295 0.15 ENSMUST00000233995.2
ENSMUST00000065758.8
ENSMUST00000235110.2
Atp6v1e2
ATPase, H+ transporting, lysosomal V1 subunit E2
chr1_+_156386414 0.15 ENSMUST00000166172.9
ENSMUST00000027888.13
Abl2
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr3_-_123029782 0.15 ENSMUST00000106427.8
ENSMUST00000198584.2
Synpo2
synaptopodin 2
chr3_+_137770813 0.14 ENSMUST00000163080.3
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr12_+_86781154 0.14 ENSMUST00000095527.6
Lrrc74a
leucine rich repeat containing 74A
chr2_+_61876806 0.14 ENSMUST00000102735.10
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr2_-_25471703 0.14 ENSMUST00000114217.3
ENSMUST00000191602.2
Ajm1
apical junction component 1
chr13_+_16189041 0.14 ENSMUST00000164993.2
Inhba
inhibin beta-A
chr7_+_17799863 0.13 ENSMUST00000108487.9
Ceacam12
carcinoembryonic antigen-related cell adhesion molecule 12
chr15_-_89726063 0.13 ENSMUST00000029441.4
Syt10
synaptotagmin X
chr5_-_142594549 0.13 ENSMUST00000037048.9
Mmd2
monocyte to macrophage differentiation-associated 2
chr15_+_99870787 0.13 ENSMUST00000231160.2
Larp4
La ribonucleoprotein domain family, member 4
chr4_-_110149916 0.13 ENSMUST00000106601.8
Elavl4
ELAV like RNA binding protein 4
chr1_-_131441962 0.12 ENSMUST00000185445.3
Srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr3_+_125197722 0.12 ENSMUST00000173932.8
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr9_+_26910995 0.11 ENSMUST00000213770.2
ENSMUST00000213683.2
ENSMUST00000039161.10
Thyn1
thymocyte nuclear protein 1
chr7_+_17799849 0.11 ENSMUST00000032520.9
Ceacam12
carcinoembryonic antigen-related cell adhesion molecule 12
chr7_+_17799889 0.11 ENSMUST00000108483.2
Ceacam12
carcinoembryonic antigen-related cell adhesion molecule 12
chr6_-_52203146 0.10 ENSMUST00000114425.3
Hoxa9
homeobox A9
chr6_-_12749409 0.10 ENSMUST00000119581.7
Thsd7a
thrombospondin, type I, domain containing 7A
chr18_+_74349189 0.10 ENSMUST00000025444.8
Cxxc1
CXXC finger 1 (PHD domain)
chr8_+_11778039 0.10 ENSMUST00000110909.9
Arhgef7
Rho guanine nucleotide exchange factor (GEF7)
chr6_+_17636979 0.09 ENSMUST00000015877.14
ENSMUST00000152005.3
Capza2
capping protein (actin filament) muscle Z-line, alpha 2
chr2_-_79287095 0.09 ENSMUST00000041099.5
Neurod1
neurogenic differentiation 1
chr7_-_119461027 0.09 ENSMUST00000137888.2
ENSMUST00000142120.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr16_-_17540685 0.09 ENSMUST00000232163.2
ENSMUST00000232202.2
ENSMUST00000080936.14
ENSMUST00000232645.2
ENSMUST00000232431.2
Med15
mediator complex subunit 15
chr2_-_36782948 0.09 ENSMUST00000217215.3
Olfr353
olfactory receptor 353
chr11_+_53324126 0.08 ENSMUST00000018382.7
Gdf9
growth differentiation factor 9
chr7_-_133203838 0.08 ENSMUST00000033275.4
Tex36
testis expressed 36
chr16_-_26810402 0.08 ENSMUST00000231299.2
Gmnc
geminin coiled-coil domain containing
chr11_+_73051228 0.07 ENSMUST00000006104.10
ENSMUST00000135202.8
ENSMUST00000136894.3
P2rx5
purinergic receptor P2X, ligand-gated ion channel, 5
chr3_-_10366229 0.06 ENSMUST00000119761.2
ENSMUST00000029043.13
Fabp12
fatty acid binding protein 12
chr11_-_69811717 0.05 ENSMUST00000152589.2
ENSMUST00000108612.8
ENSMUST00000108611.8
Eif5a
eukaryotic translation initiation factor 5A
chr4_+_136150835 0.05 ENSMUST00000088677.5
ENSMUST00000121571.8
ENSMUST00000117699.2
Htr1d
5-hydroxytryptamine (serotonin) receptor 1D
chr6_-_3494587 0.05 ENSMUST00000049985.15
Hepacam2
HEPACAM family member 2
chr6_-_124208815 0.05 ENSMUST00000233936.2
ENSMUST00000100968.4
Vmn2r27
vomeronasal 2, receptor27
chr7_+_55443931 0.05 ENSMUST00000205796.2
Tubgcp5
tubulin, gamma complex associated protein 5
chr7_+_55443893 0.05 ENSMUST00000032627.5
Tubgcp5
tubulin, gamma complex associated protein 5
chr2_-_156022054 0.04 ENSMUST00000126992.8
ENSMUST00000146288.8
ENSMUST00000029149.13
ENSMUST00000109587.9
ENSMUST00000109584.8
Rbm39
RNA binding motif protein 39
chr16_-_17540805 0.04 ENSMUST00000012259.9
ENSMUST00000232236.2
Med15
mediator complex subunit 15
chr16_+_43056218 0.04 ENSMUST00000146708.8
Zbtb20
zinc finger and BTB domain containing 20
chr12_+_86781141 0.03 ENSMUST00000223308.2
Lrrc74a
leucine rich repeat containing 74A
chr11_+_73244561 0.03 ENSMUST00000108465.4
Olfr20
olfactory receptor 20
chr14_-_79461316 0.03 ENSMUST00000040802.5
Zfp957
zinc finger protein 957
chr2_+_111491764 0.03 ENSMUST00000213511.2
ENSMUST00000207228.3
ENSMUST00000208983.2
Olfr1299
Gm44840
olfactory receptor 1299
predicted gene 44840
chr11_+_117157024 0.02 ENSMUST00000019038.15
Septin9
septin 9
chr11_+_49138278 0.02 ENSMUST00000109194.2
Mgat1
mannoside acetylglucosaminyltransferase 1
chr11_-_76468527 0.02 ENSMUST00000176179.8
Abr
active BCR-related gene
chr6_-_113478779 0.02 ENSMUST00000101059.4
ENSMUST00000204268.3
ENSMUST00000205170.2
ENSMUST00000205075.2
ENSMUST00000204134.3
Prrt3
proline-rich transmembrane protein 3
chr15_-_27788693 0.02 ENSMUST00000226287.2
Trio
triple functional domain (PTPRF interacting)
chr1_+_9978863 0.01 ENSMUST00000052843.12
ENSMUST00000171802.8
ENSMUST00000125294.9
ENSMUST00000140948.9
Mcmdc2
minichromosome maintenance domain containing 2
chr16_-_59090028 0.01 ENSMUST00000099656.2
Olfr201
olfactory receptor 201
chr6_+_91881193 0.01 ENSMUST00000205686.2
4930590J08Rik
RIKEN cDNA 4930590J08 gene
chr15_+_101013704 0.01 ENSMUST00000229954.2
Ankrd33
ankyrin repeat domain 33
chr19_-_11833365 0.01 ENSMUST00000079875.4
Olfr1418
olfactory receptor 1418
chr15_+_101013619 0.00 ENSMUST00000070875.8
ENSMUST00000231158.2
Ankrd33
ankyrin repeat domain 33
chr16_-_57113207 0.00 ENSMUST00000023434.15
ENSMUST00000120112.2
ENSMUST00000119407.8
Tmem30c
transmembrane protein 30C
chr3_-_107240989 0.00 ENSMUST00000061772.11
Rbm15
RNA binding motif protein 15
chr2_-_38955452 0.00 ENSMUST00000112850.9
Golga1
golgi autoantigen, golgin subfamily a, 1
chr15_+_99870714 0.00 ENSMUST00000230956.2
Larp4
La ribonucleoprotein domain family, member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Atoh1_Bhlhe23

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.7 5.4 GO:0032796 uropod organization(GO:0032796) early endosome to recycling endosome transport(GO:0061502)
0.6 1.8 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
0.4 1.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.3 1.7 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.3 1.7 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.3 1.3 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.2 0.7 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.2 0.7 GO:0007225 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.2 1.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 0.6 GO:0046832 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.2 0.6 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 0.8 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 0.9 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 3.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.5 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 1.1 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.6 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.1 0.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 0.4 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.5 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.1 0.7 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.3 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.6 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.3 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.6 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.5 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.5 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.6 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 3.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.4 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 0.7 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.2 5.4 GO:0032426 stereocilium tip(GO:0032426)
0.2 1.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.8 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.4 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.1 GO:0043512 inhibin A complex(GO:0043512)
0.0 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.7 GO:0042588 zymogen granule(GO:0042588)
0.0 3.4 GO:0005643 nuclear pore(GO:0005643)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.9 GO:0031430 M band(GO:0031430)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 5.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 0.7 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 1.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.9 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 1.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 5.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 1.1 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.7 GO:0031489 myosin V binding(GO:0031489)
0.1 0.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.7 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0034711 inhibin binding(GO:0034711)
0.0 0.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.9 GO:0016208 AMP binding(GO:0016208)
0.0 0.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 1.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 3.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation