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GSE58827: Dynamics of the Mouse Liver

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Results for Creb3

Z-value: 1.09

Motif logo

Transcription factors associated with Creb3

Gene Symbol Gene ID Gene Info
ENSMUSG00000028466.16 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Creb3mm39_v1_chr4_+_43562706_435629470.363.0e-02Click!

Activity profile of Creb3 motif

Sorted Z-values of Creb3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_58152295 8.17 ENSMUST00000040999.14
ENSMUST00000162011.3
aldehyde oxidase 3
chr13_-_4573312 7.68 ENSMUST00000221564.2
ENSMUST00000078239.5
ENSMUST00000080361.13
aldo-keto reductase family 1, member C20
chr17_+_35658131 7.07 ENSMUST00000071951.14
ENSMUST00000116598.10
ENSMUST00000078205.14
ENSMUST00000076256.8
histocompatibility 2, Q region locus 7
chr2_+_172994841 6.35 ENSMUST00000029017.6
phosphoenolpyruvate carboxykinase 1, cytosolic
chr3_+_123061094 6.04 ENSMUST00000047923.12
ENSMUST00000200333.2
Sec24 related gene family, member D (S. cerevisiae)
chr7_-_34914675 5.88 ENSMUST00000118444.3
ENSMUST00000122409.8
low density lipoprotein receptor-related protein 3
chr9_+_103940575 4.68 ENSMUST00000120854.8
acyl-Coenzyme A dehydrogenase family, member 11
chr4_-_104967032 4.33 ENSMUST00000030243.8
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr17_-_57535003 4.16 ENSMUST00000177046.2
ENSMUST00000024988.15
complement component 3
chr10_-_4382311 4.03 ENSMUST00000126102.8
ENSMUST00000131853.2
ENSMUST00000042251.11
required for meiotic nuclear division 1 homolog
chr9_+_44290832 3.94 ENSMUST00000161318.8
ENSMUST00000217019.2
ENSMUST00000160902.8
hypoxia up-regulated 1
chr16_+_13721016 3.92 ENSMUST00000128757.8
Mpv17 transgene, kidney disease mutant-like
chr9_+_44290787 3.79 ENSMUST00000066601.13
hypoxia up-regulated 1
chrX_+_72830668 3.78 ENSMUST00000002090.3
signal sequence receptor, delta
chr11_-_96807192 3.70 ENSMUST00000144731.8
ENSMUST00000127048.8
CDK5 regulatory subunit associated protein 3
chr10_-_4382283 3.64 ENSMUST00000155172.8
required for meiotic nuclear division 1 homolog
chr11_-_61745843 3.56 ENSMUST00000004920.4
unc-51 like kinase 2
chrX_+_72830607 3.49 ENSMUST00000166518.8
signal sequence receptor, delta
chr10_+_41395410 3.44 ENSMUST00000019962.15
CD164 antigen
chr2_+_155118217 3.38 ENSMUST00000029128.4
microtubule-associated protein 1 light chain 3 alpha
chr11_-_96807273 3.36 ENSMUST00000103152.11
CDK5 regulatory subunit associated protein 3
chr14_-_59835285 3.31 ENSMUST00000022555.11
ENSMUST00000225839.2
ENSMUST00000056997.15
ENSMUST00000171683.3
ENSMUST00000167100.9
cytidine and dCMP deaminase domain containing 1
chr1_-_183150867 3.30 ENSMUST00000194543.4
melanoma inhibitory activity 3
chr2_+_71884943 3.24 ENSMUST00000028525.6
Rap guanine nucleotide exchange factor (GEF) 4
chr2_-_168584020 3.24 ENSMUST00000109177.8
ATPase, class II, type 9A
chr10_+_41395870 3.00 ENSMUST00000189300.2
CD164 antigen
chr11_-_86884507 2.91 ENSMUST00000018571.5
yippee like 2
chr11_-_96807233 2.80 ENSMUST00000130774.2
CDK5 regulatory subunit associated protein 3
chr11_-_72686853 2.69 ENSMUST00000156294.8
cytochrome b5 domain containing 2
chr2_-_143853122 2.67 ENSMUST00000016072.12
ENSMUST00000037875.6
ribosome binding protein 1
chr5_+_28276353 2.63 ENSMUST00000059155.11
insulin induced gene 1
chr10_+_128158413 2.58 ENSMUST00000219836.2
canopy FGF signaling regulator 2
chr5_+_113873864 2.55 ENSMUST00000065698.7
FIC domain containing
chr4_-_118401185 2.51 ENSMUST00000128098.8
transmembrane protein 125
chr11_-_60702081 2.51 ENSMUST00000018744.15
serine hydroxymethyltransferase 1 (soluble)
chr7_+_101859542 2.43 ENSMUST00000140631.2
ENSMUST00000120879.8
ENSMUST00000146996.8
post-GPI attachment to proteins 2
chr10_-_67120959 2.41 ENSMUST00000159002.2
ENSMUST00000077839.13
nuclear receptor binding factor 2
chr11_+_94544593 2.40 ENSMUST00000025278.8
mitochondrial ribosomal protein L27
chr11_-_72686627 2.38 ENSMUST00000079681.6
cytochrome b5 domain containing 2
chr8_-_106863423 2.37 ENSMUST00000146940.2
epithelial splicing regulatory protein 2
chr11_+_70104736 2.36 ENSMUST00000171032.8
solute carrier family 16 (monocarboxylic acid transporters), member 11
chr2_+_155224105 2.35 ENSMUST00000134218.2
transformation related protein 53 inducible nuclear protein 2
chr10_+_128158328 2.25 ENSMUST00000219037.2
ENSMUST00000026446.4
canopy FGF signaling regulator 2
chr7_+_26895206 2.23 ENSMUST00000179391.8
ENSMUST00000108379.8
cDNA sequence BC024978
chr11_-_51647290 2.22 ENSMUST00000109097.9
Sec24 related gene family, member A (S. cerevisiae)
chr4_+_59003121 2.20 ENSMUST00000095070.4
ENSMUST00000174664.2
DnaJ heat shock protein family (Hsp40) member C25
predicted gene 20503
chr8_-_106863521 2.20 ENSMUST00000115979.9
epithelial splicing regulatory protein 2
chr19_-_6886965 2.19 ENSMUST00000173091.2
peroxiredoxin 5
chr8_+_91635192 2.15 ENSMUST00000211403.2
chromodomain helicase DNA binding protein 9
chr3_+_89366632 2.12 ENSMUST00000107410.8
phosphomevalonate kinase
chr19_-_6887361 2.08 ENSMUST00000025904.12
peroxiredoxin 5
chr1_+_24717711 2.08 ENSMUST00000191471.7
LMBR1 domain containing 1
chr12_+_51424343 2.03 ENSMUST00000219434.2
ENSMUST00000021335.7
Sec1 family domain containing 1
chr6_-_71121347 1.97 ENSMUST00000160918.8
threonine synthase-like 2 (bacterial)
chr6_-_108162513 1.96 ENSMUST00000167338.8
ENSMUST00000172188.2
ENSMUST00000032191.16
sulfatase modifying factor 1
chr7_+_128125339 1.93 ENSMUST00000033136.9
BCL2-associated athanogene 3
chr9_-_44920899 1.89 ENSMUST00000102832.3
CD3 antigen, epsilon polypeptide
chr6_-_119825081 1.89 ENSMUST00000183703.8
ENSMUST00000183911.8
ELKS/RAB6-interacting/CAST family member 1
chr1_+_157334347 1.87 ENSMUST00000027881.15
SEC16 homolog B (S. cerevisiae)
chr6_-_71121324 1.87 ENSMUST00000074241.9
threonine synthase-like 2 (bacterial)
chr9_-_20887967 1.86 ENSMUST00000214218.2
sphingosine-1-phosphate receptor 2
chr17_+_46694646 1.85 ENSMUST00000113481.9
ENSMUST00000138127.8
zinc finger protein 318
chr17_-_56490887 1.84 ENSMUST00000019723.8
myeloid derived growth factor
chr1_+_157334298 1.83 ENSMUST00000086130.9
SEC16 homolog B (S. cerevisiae)
chr19_-_6886898 1.80 ENSMUST00000238095.2
peroxiredoxin 5
chr2_-_104324035 1.78 ENSMUST00000111124.8
homeodomain interacting protein kinase 3
chr17_+_45874800 1.77 ENSMUST00000224905.2
ENSMUST00000226086.2
ENSMUST00000041353.7
solute carrier family 35, member B2
chr9_-_103940247 1.74 ENSMUST00000035166.12
ubiquitin-like modifier activating enzyme 5
chr7_+_44145987 1.72 ENSMUST00000107927.5
family with sequence similarity 71, member E1
chr11_-_51647204 1.71 ENSMUST00000109092.8
ENSMUST00000064297.5
Sec24 related gene family, member A (S. cerevisiae)
chr7_-_44145830 1.71 ENSMUST00000118515.9
ENSMUST00000138328.3
ENSMUST00000239015.2
ENSMUST00000118808.9
ER membrane protein complex subunit 10
chr2_+_80145805 1.71 ENSMUST00000028392.8
DnaJ heat shock protein family (Hsp40) member C10
chr11_+_119989736 1.70 ENSMUST00000106223.4
ENSMUST00000185558.2
NADH:ubiquinone oxidoreductase complex assembly factor 8
chr7_+_44146012 1.70 ENSMUST00000205422.2
family with sequence similarity 71, member E1
chr2_+_67578556 1.69 ENSMUST00000180887.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr19_+_11943265 1.68 ENSMUST00000025590.11
oxysterol binding protein
chr1_+_24717722 1.65 ENSMUST00000186096.7
LMBR1 domain containing 1
chr12_+_69230931 1.63 ENSMUST00000060579.10
mannoside acetylglucosaminyltransferase 2
chr7_-_121666486 1.63 ENSMUST00000033159.4
glutamyl-tRNA synthetase 2, mitochondrial
chr1_+_75119419 1.56 ENSMUST00000097694.11
ENSMUST00000190240.7
reticulophagy regulator family member 2
chr11_+_53241561 1.55 ENSMUST00000060945.12
AF4/FMR2 family, member 4
chr10_-_115087309 1.55 ENSMUST00000020339.10
TBC1 domain family, member 15
chr19_+_8719033 1.52 ENSMUST00000176314.8
ENSMUST00000073430.14
ENSMUST00000175901.8
syntaxin 5A
chr1_-_175319842 1.52 ENSMUST00000195324.6
ENSMUST00000192227.6
ENSMUST00000194555.6
regulator of G protein signaling 7
chr10_-_128758757 1.49 ENSMUST00000135161.2
retinol dehydrogenase 5
chr1_+_75119809 1.47 ENSMUST00000186037.7
ENSMUST00000187901.2
reticulophagy regulator family member 2
chr6_-_119825020 1.46 ENSMUST00000184864.8
ELKS/RAB6-interacting/CAST family member 1
chr9_+_43996236 1.45 ENSMUST00000065461.9
ENSMUST00000176416.8
ubiquitin specific peptidase 2
chr11_-_86698484 1.45 ENSMUST00000018569.14
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr14_-_55880980 1.45 ENSMUST00000132338.8
transmembrane 9 superfamily member 1
chr19_+_8718777 1.44 ENSMUST00000176381.8
syntaxin 5A
chr10_+_121200984 1.43 ENSMUST00000040344.7
glucosamine (N-acetyl)-6-sulfatase
chr9_-_64928927 1.42 ENSMUST00000036615.7
3-hydroxyacyl-CoA dehydratase 3
chr9_+_59446823 1.40 ENSMUST00000026262.8
hexosaminidase A
chr11_-_20781009 1.40 ENSMUST00000047028.9
lectin, galactoside binding-like
chr14_-_55880708 1.39 ENSMUST00000120041.8
ENSMUST00000121937.8
ENSMUST00000133707.2
ENSMUST00000002391.15
ENSMUST00000121791.8
transmembrane 9 superfamily member 1
chr10_-_128759817 1.39 ENSMUST00000131271.2
biogenesis of lysosomal organelles complex-1, subunit 1
chr16_-_5021843 1.38 ENSMUST00000147567.2
ENSMUST00000023911.11
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr14_-_55881257 1.37 ENSMUST00000122358.8
transmembrane 9 superfamily member 1
chr1_+_75119472 1.35 ENSMUST00000189650.7
reticulophagy regulator family member 2
chrX_-_59937036 1.33 ENSMUST00000135107.4
SRY (sex determining region Y)-box 3
chr14_-_55881177 1.31 ENSMUST00000138085.2
transmembrane 9 superfamily member 1
chr19_+_8718837 1.28 ENSMUST00000177373.8
ENSMUST00000010254.16
syntaxin 5A
chr1_-_93373364 1.27 ENSMUST00000190321.7
ENSMUST00000042498.14
high density lipoprotein (HDL) binding protein
chr1_+_171173252 1.27 ENSMUST00000006579.5
prefoldin 2
chr7_+_45434755 1.26 ENSMUST00000233503.2
ENSMUST00000120005.10
ENSMUST00000211609.2
lemur tyrosine kinase 3
chr2_-_6327884 1.25 ENSMUST00000238876.2
RIKEN cDNA 1700014B07 gene
chr8_+_111760521 1.25 ENSMUST00000034441.8
alanyl-tRNA synthetase
chr16_-_4867703 1.24 ENSMUST00000115844.3
ENSMUST00000023189.15
glyoxylate reductase 1 homolog (Arabidopsis)
chr4_+_154041687 1.24 ENSMUST00000105645.9
ENSMUST00000058393.9
ENSMUST00000141493.8
RIKEN cDNA A430005L14 gene
chr7_+_44146029 1.23 ENSMUST00000205359.2
family with sequence similarity 71, member E1
chr2_-_132089667 1.21 ENSMUST00000110163.8
ENSMUST00000180286.2
ENSMUST00000028816.9
transmembrane protein 230
chr11_+_72686990 1.19 ENSMUST00000069395.7
ENSMUST00000172220.8
zinc finger, ZZ-type with EF hand domain 1
chr6_-_134874778 1.18 ENSMUST00000165392.8
ENSMUST00000204880.3
ENSMUST00000203409.3
ENSMUST00000046255.14
ENSMUST00000111932.8
ENSMUST00000149375.8
ENSMUST00000116515.9
G protein-coupled receptor 19
chr1_+_171910073 1.17 ENSMUST00000135192.8
coatomer protein complex subunit alpha
chr7_+_121666388 1.15 ENSMUST00000033158.6
ubiquitin family domain containing 1
chr8_+_46428551 1.14 ENSMUST00000034051.7
ENSMUST00000150943.2
UFM1-specific peptidase 2
chr11_+_52123016 1.13 ENSMUST00000109072.2
S-phase kinase-associated protein 1
chr1_+_185095232 1.12 ENSMUST00000046514.13
glutamyl-prolyl-tRNA synthetase
chr1_-_183126875 1.11 ENSMUST00000195233.3
melanoma inhibitory activity 3
chr6_-_119825054 1.11 ENSMUST00000079582.5
ELKS/RAB6-interacting/CAST family member 1
chr4_-_150994260 1.10 ENSMUST00000134751.8
ENSMUST00000030805.14
Parkinson disease (autosomal recessive, early onset) 7
chr9_+_108216466 1.09 ENSMUST00000193987.2
glutathione peroxidase 1
chr17_-_26727437 1.09 ENSMUST00000236661.2
ENSMUST00000025025.7
dual specificity phosphatase 1
chr9_-_50472605 1.06 ENSMUST00000034568.7
testis expressed 12
chr2_+_70491901 1.06 ENSMUST00000112201.8
ENSMUST00000028509.11
ENSMUST00000133432.8
ENSMUST00000112205.2
golgi reassembly stacking protein 2
chr5_+_107479023 1.06 ENSMUST00000031215.15
ENSMUST00000112677.10
bromodomain, testis-specific
chr7_-_118132520 1.05 ENSMUST00000209146.2
ENSMUST00000098090.10
ENSMUST00000032887.4
demethyl-Q 7
chr18_+_65933586 1.04 ENSMUST00000025394.14
ENSMUST00000236847.2
ENSMUST00000153193.3
SEC11 homolog C, signal peptidase complex subunit
chr10_-_80895949 1.04 ENSMUST00000219401.2
ENSMUST00000220317.2
ENSMUST00000005067.6
ENSMUST00000218208.2
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr16_-_13720949 1.03 ENSMUST00000023361.12
ENSMUST00000115802.2
pyridoxal-dependent decarboxylase domain containing 1
chr2_+_71283620 1.03 ENSMUST00000037210.9
methionyl aminopeptidase type 1D (mitochondrial)
chr5_+_129970882 1.03 ENSMUST00000201855.2
ENSMUST00000073945.6
vitamin K epoxide reductase complex, subunit 1-like 1
chr16_+_36695479 1.02 ENSMUST00000023534.7
ENSMUST00000114812.9
ENSMUST00000134616.8
golgi autoantigen, golgin subfamily b, macrogolgin 1
chr11_+_52122836 1.01 ENSMUST00000037324.12
ENSMUST00000166537.8
S-phase kinase-associated protein 1
chr6_+_29348068 1.00 ENSMUST00000173216.8
ENSMUST00000173694.5
ENSMUST00000172974.8
ENSMUST00000031779.17
ENSMUST00000090481.14
calumenin
chr4_+_109835224 1.00 ENSMUST00000061187.4
doublesex and mab-3 related transcription factor like family A2
chr16_-_13720915 0.99 ENSMUST00000115803.9
pyridoxal-dependent decarboxylase domain containing 1
chr9_-_50472620 0.98 ENSMUST00000217236.2
testis expressed 12
chr3_-_154798982 0.98 ENSMUST00000066568.6
fucose-1-phosphate guanylyltransferase
chr10_-_121933276 0.97 ENSMUST00000140299.3
ribitol xylosyltransferase 1
chr8_-_34614187 0.96 ENSMUST00000033910.9
leptin receptor overlapping transcript-like 1
chr8_+_109441276 0.95 ENSMUST00000043896.10
zinc finger homeobox 3
chr7_+_16609227 0.95 ENSMUST00000108493.3
dishevelled-binding antagonist of beta-catenin 3
chr7_-_46445085 0.94 ENSMUST00000123725.2
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
chr1_-_171910324 0.94 ENSMUST00000003550.11
nicastrin
chr11_+_54329014 0.93 ENSMUST00000046835.14
folliculin interacting protein 1
chr1_-_93373145 0.92 ENSMUST00000186787.7
high density lipoprotein (HDL) binding protein
chr3_+_89153704 0.92 ENSMUST00000168900.3
keratinocyte associated protein 2
chr1_+_171910343 0.91 ENSMUST00000027833.12
coatomer protein complex subunit alpha
chrX_-_135642025 0.91 ENSMUST00000155207.8
ENSMUST00000080411.13
ENSMUST00000169418.8
mortality factor 4 like 2
chr17_-_84773544 0.90 ENSMUST00000047524.10
thyroid adenoma associated
chr1_+_130947580 0.89 ENSMUST00000016673.6
interleukin 10
chr13_-_38712387 0.87 ENSMUST00000035988.16
thioredoxin domain containing 5
chr2_-_90900628 0.86 ENSMUST00000111436.3
ENSMUST00000073575.12
solute carrier family 39 (metal ion transporter), member 13
chr17_-_28569721 0.84 ENSMUST00000156862.3
TEA domain family member 3
chr11_+_82671934 0.83 ENSMUST00000092849.12
ENSMUST00000021039.12
ENSMUST00000080461.12
ENSMUST00000173347.8
ENSMUST00000173727.8
ENSMUST00000173009.8
ENSMUST00000131537.9
ENSMUST00000173722.8
ligase III, DNA, ATP-dependent
chr12_+_71356632 0.83 ENSMUST00000061273.12
ENSMUST00000150639.2
dishevelled-binding antagonist of beta-catenin 1
chr9_+_108216433 0.83 ENSMUST00000191997.2
glutathione peroxidase 1
chr8_+_95328694 0.83 ENSMUST00000211983.2
ring finger and SPRY domain containing 1
chr4_+_137321451 0.81 ENSMUST00000105840.8
ENSMUST00000105839.8
ENSMUST00000055131.13
ENSMUST00000105838.8
ubiquitin specific peptidase 48
chr1_+_119453849 0.81 ENSMUST00000183952.2
transmembrane protein 185B
chr7_+_127511681 0.80 ENSMUST00000033070.9
K(lysine) acetyltransferase 8
chr18_-_84703738 0.79 ENSMUST00000025546.17
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr16_-_13720863 0.79 ENSMUST00000115804.9
pyridoxal-dependent decarboxylase domain containing 1
chrX_+_106193060 0.79 ENSMUST00000125676.8
ENSMUST00000180182.2
purinergic receptor P2Y, G-protein coupled 10B
chr17_+_34341766 0.78 ENSMUST00000042121.11
histocompatibility 2, class II, locus DMa
chr11_+_69891398 0.77 ENSMUST00000019362.15
ENSMUST00000190940.2
dishevelled segment polarity protein 2
chr10_+_77458197 0.77 ENSMUST00000172772.2
ubiquitin-conjugating enzyme E2G 2
chr2_-_132089543 0.77 ENSMUST00000110164.8
transmembrane protein 230
chr15_-_99717956 0.76 ENSMUST00000109024.9
LIM domain and actin binding 1
chr3_+_30847024 0.74 ENSMUST00000029256.9
SEC62 homolog (S. cerevisiae)
chr14_-_78774201 0.74 ENSMUST00000123853.9
A kinase (PRKA) anchor protein 11
chr7_+_45522551 0.74 ENSMUST00000211234.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr9_-_20888054 0.73 ENSMUST00000054197.7
sphingosine-1-phosphate receptor 2
chr3_+_154799223 0.72 ENSMUST00000194376.2
leucine-rich repeats and IQ motif containing 3
chr12_-_4088905 0.71 ENSMUST00000111178.2
EFR3 homolog B
chr2_+_23046381 0.70 ENSMUST00000028117.4
YME1-like 1 (S. cerevisiae)
chr1_+_181952302 0.70 ENSMUST00000111018.2
ENSMUST00000027792.6
signal recognition particle 9
chr11_-_69871320 0.69 ENSMUST00000143175.2
elongator acetyltransferase complex subunit 5
chr5_+_120569764 0.68 ENSMUST00000031591.10
LIM homeobox protein 5
chr15_+_34238174 0.68 ENSMUST00000022867.5
ENSMUST00000226627.2
lysosomal-associated protein transmembrane 4B
chr14_+_79825131 0.68 ENSMUST00000054908.10
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr11_-_29975916 0.67 ENSMUST00000058902.6
echinoderm microtubule associated protein like 6
chr1_+_192855776 0.67 ENSMUST00000161235.3
ENSMUST00000160077.2
ENSMUST00000178744.2
ENSMUST00000192189.2
ENSMUST00000110831.4
ENSMUST00000191613.2
RIKEN cDNA A130010J15 gene
chr2_+_154975419 0.67 ENSMUST00000029126.15
ENSMUST00000109685.8
itchy, E3 ubiquitin protein ligase
chr3_+_154799163 0.66 ENSMUST00000192383.6
leucine-rich repeats and IQ motif containing 3
chr18_+_67597929 0.66 ENSMUST00000025411.9
PRELI domain containing 3A
chrX_-_7440480 0.66 ENSMUST00000115742.9
ENSMUST00000150787.8
protein phosphatase 1, regulatory subunit 3F
chr18_-_31742946 0.64 ENSMUST00000060396.7
solute carrier family 25, member 46
chr8_+_95328558 0.64 ENSMUST00000060389.10
ENSMUST00000212729.2
ENSMUST00000121101.2
ring finger and SPRY domain containing 1
chr18_-_35348049 0.63 ENSMUST00000091636.5
ENSMUST00000236680.2
leucine rich repeat transmembrane neuronal 2
chr17_-_34340918 0.62 ENSMUST00000151986.2
bromodomain containing 2
chr16_-_36695166 0.62 ENSMUST00000075946.12
ELL associated factor 2
chrX_+_106193167 0.62 ENSMUST00000137107.2
ENSMUST00000067249.3
purinergic receptor P2Y, G-protein coupled 10B
chr3_+_154799063 0.61 ENSMUST00000029833.13
leucine-rich repeats and IQ motif containing 3
chr13_-_100969878 0.61 ENSMUST00000067246.6
solute carrier family 30 (zinc transporter), member 5
chr13_-_54836077 0.60 ENSMUST00000150626.2
ENSMUST00000134177.8
ring finger protein 44
chr10_+_57508203 0.60 ENSMUST00000177438.8
protein kinase inhibitor beta, cAMP dependent, testis specific
chr9_-_103243039 0.59 ENSMUST00000035484.11
carnitine deficiency-associated gene expressed in ventricle 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Creb3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.2 GO:0009115 xanthine catabolic process(GO:0009115)
1.6 6.3 GO:0006114 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
1.5 6.1 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
1.4 11.6 GO:0071569 protein ufmylation(GO:0071569)
1.0 4.2 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.9 17.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.9 3.7 GO:0038016 insulin receptor internalization(GO:0038016)
0.8 2.5 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.8 3.8 GO:0006566 threonine metabolic process(GO:0006566)
0.7 7.7 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.7 4.8 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.7 3.9 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.6 3.2 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.6 7.7 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.6 2.2 GO:0010269 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) response to selenium ion(GO:0010269)
0.5 2.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.4 4.3 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.4 1.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.4 4.2 GO:0090166 Golgi disassembly(GO:0090166)
0.4 2.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.4 3.6 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.3 2.0 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.3 3.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.3 0.9 GO:0060300 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) regulation of cytokine activity(GO:0060300)
0.3 1.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.3 1.4 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.3 0.8 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298)
0.3 1.1 GO:1902958 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) glycolate biosynthetic process(GO:0046295) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.3 1.6 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.3 1.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.3 0.8 GO:0002501 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.3 1.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 1.0 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.3 2.6 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.2 4.3 GO:0055089 fatty acid homeostasis(GO:0055089)
0.2 0.7 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.2 0.6 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.2 1.8 GO:0051503 adenine nucleotide transport(GO:0051503)
0.2 0.6 GO:1902868 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.2 0.8 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 1.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 1.7 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 4.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 4.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.2 1.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.2 8.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 7.1 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 1.0 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.7 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.6 GO:0070829 heterochromatin maintenance(GO:0070829)
0.1 0.9 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 1.4 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.5 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 1.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.7 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.1 1.8 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.7 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 4.6 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.8 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.9 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.8 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.1 0.3 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.1 0.8 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 6.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.7 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.1 0.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 2.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 1.4 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 1.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 1.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 1.5 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 0.4 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.1 1.0 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.9 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.7 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 2.4 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 1.1 GO:0007141 male meiosis I(GO:0007141)
0.0 1.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.9 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 1.3 GO:0007530 sex determination(GO:0007530)
0.0 0.9 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 0.8 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 1.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0021763 subthalamic nucleus development(GO:0021763) superior vena cava morphogenesis(GO:0060578)
0.0 0.5 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 1.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0098970 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.9 GO:0044819 mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819)
0.0 6.9 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 2.2 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.0 1.1 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 2.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.4 GO:0061088 cobalt ion transport(GO:0006824) sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 1.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.6 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 1.1 GO:0001706 endoderm formation(GO:0001706)
0.0 1.8 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.4 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 2.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0016093 polyprenol metabolic process(GO:0016093)
0.0 1.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 1.4 GO:0030203 glycosaminoglycan metabolic process(GO:0030203)
0.0 0.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 2.4 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 2.0 GO:0048489 synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480)
0.0 2.1 GO:0007601 visual perception(GO:0007601)
0.0 0.6 GO:0051452 intracellular pH reduction(GO:0051452)
0.0 1.5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.0 GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393)
0.0 0.4 GO:0032456 endocytic recycling(GO:0032456)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.6 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.6 3.2 GO:0044316 cone cell pedicle(GO:0044316)
0.6 9.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.6 10.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.5 7.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 2.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 2.4 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.3 2.4 GO:0097413 Lewy body(GO:0097413)
0.3 4.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 0.9 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 3.4 GO:0044754 autolysosome(GO:0044754)
0.2 3.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 0.6 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 6.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 4.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 0.5 GO:0055087 Ski complex(GO:0055087)
0.2 2.0 GO:0000801 central element(GO:0000801)
0.2 1.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 4.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 2.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.3 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.8 GO:0072487 MSL complex(GO:0072487)
0.1 1.0 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 0.7 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 3.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 4.2 GO:0031201 SNARE complex(GO:0031201)
0.1 1.4 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 1.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.9 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.2 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.1 1.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 2.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 10.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.5 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.0 1.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 5.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 5.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 1.6 GO:0005795 Golgi stack(GO:0005795)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 4.2 GO:0072562 blood microparticle(GO:0072562)
0.0 7.9 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 3.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 6.2 GO:0005874 microtubule(GO:0005874)
0.0 1.9 GO:0030018 Z disc(GO:0030018)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.6 8.2 GO:0030151 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdenum ion binding(GO:0030151)
1.6 6.3 GO:0070905 serine binding(GO:0070905)
1.6 4.7 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
1.5 6.1 GO:0072541 peroxynitrite reductase activity(GO:0072541)
1.5 4.4 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.6 1.8 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.4 1.7 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.4 7.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.4 1.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.4 1.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.4 9.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.4 1.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 1.0 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.3 3.7 GO:0031419 cobalamin binding(GO:0031419)
0.3 3.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 7.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.3 1.4 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.3 1.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.3 1.1 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.2 4.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 1.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 1.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.6 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 0.7 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 1.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 2.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 1.0 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.7 GO:2001069 glycogen binding(GO:2001069)
0.1 1.8 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 3.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 5.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.5 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.4 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.7 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 1.4 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 0.4 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 1.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.8 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 3.8 GO:0030552 cAMP binding(GO:0030552)
0.1 1.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 2.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 2.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.8 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 2.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 2.7 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 2.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.7 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.9 GO:0015250 water channel activity(GO:0015250)
0.0 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 5.9 GO:0000149 SNARE binding(GO:0000149)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.8 GO:0016805 dipeptidase activity(GO:0016805)
0.0 5.1 GO:0020037 heme binding(GO:0020037)
0.0 0.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 1.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 2.0 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 1.5 GO:0030332 cyclin binding(GO:0030332)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 4.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.6 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.1 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.3 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 4.0 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 1.1 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.5 GO:0008565 protein transporter activity(GO:0008565)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 4.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 2.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 2.4 PID ARF 3PATHWAY Arf1 pathway
0.1 6.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 4.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 2.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 4.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 6.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 4.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 2.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 2.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 1.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 2.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 4.4 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 3.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 3.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.8 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 3.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.6 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.9 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 2.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 3.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 3.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 2.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening