ISMARA results: Cux1

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GSE58827: Dynamics of the Mouse Liver

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Results for Cux1

Z-value: 1.34

Motif logo

Transcription factors associated with Cux1

Gene Symbol	Gene ID	Gene Info
Cux1 Ensembl NCBI MGI UniProt	ENSMUSG00000029705.18	cut-like homeobox 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Cux1	mm39_v1_chr5_-_136596299_136596390	-0.52	1.1e-03	Click!

Activity profile of Cux1 motif

Sorted Z-values of Cux1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr19_+_39275518 Show fit	12.99	ENSMUST00000003137.15	Cyp2c29 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily c, polypeptide 29
chr19_+_38995463 Show fit	11.71	ENSMUST00000025966.5	Cyp2c55 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily c, polypeptide 55
chr7_-_99345016 Show fit	10.89	ENSMUST00000107086.9	Slco2b1 Ensembl NCBI MGI UniProt Show fit	solute carrier organic anion transporter family, member 2b1
chr19_-_44396092 Show fit	10.74	ENSMUST00000041331.4	Scd1 Ensembl NCBI MGI UniProt Show fit	stearoyl-Coenzyme A desaturase 1
chr4_-_62069046 Show fit	8.51	ENSMUST00000077719.4	Mup21 Ensembl NCBI MGI UniProt Show fit	major urinary protein 21
chr13_-_4573312 Show fit	8.15	ENSMUST00000221564.2 ENSMUST00000078239.5 ENSMUST00000080361.13	Akr1c20 Ensembl NCBI MGI UniProt Show fit	aldo-keto reductase family 1, member C20
chr8_-_94006345 Show fit	7.85	ENSMUST00000034178.9	Ces1f Ensembl NCBI MGI UniProt Show fit	carboxylesterase 1F
chr7_+_26819334 Show fit	7.67	ENSMUST00000003100.10	Cyp2f2 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily f, polypeptide 2
chr7_-_99344779 Show fit	6.70	ENSMUST00000137914.2 ENSMUST00000207090.2 ENSMUST00000208225.2	Slco2b1 Ensembl NCBI MGI UniProt Show fit	solute carrier organic anion transporter family, member 2b1
chr19_-_40062174 Show fit	6.40	ENSMUST00000048959.5	Cyp2c54 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily c, polypeptide 54
chr19_-_44396269 Show fit	6.36	ENSMUST00000235741.2	Scd1 Ensembl NCBI MGI UniProt Show fit	stearoyl-Coenzyme A desaturase 1
chr4_+_115156243 Show fit	6.34	ENSMUST00000084343.4	Cyp4a12a Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily a, polypeptide 12a
chr8_-_93956143 Show fit	6.06	ENSMUST00000176282.2 ENSMUST00000034173.14	Ces1e Ensembl NCBI MGI UniProt Show fit	carboxylesterase 1E
chr17_+_24955613 Show fit	5.88	ENSMUST00000115262.9	Msrb1 Ensembl NCBI MGI UniProt Show fit	methionine sulfoxide reductase B1
chr11_+_78389913 Show fit	5.77	ENSMUST00000017488.5	Vtn Ensembl NCBI MGI UniProt Show fit	vitronectin
chr19_+_39980868 Show fit	5.69	ENSMUST00000049178.3	Cyp2c37 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2. subfamily c, polypeptide 37
chr7_-_99344832 Show fit	5.66	ENSMUST00000145381.8	Slco2b1 Ensembl NCBI MGI UniProt Show fit	solute carrier organic anion transporter family, member 2b1
chr16_+_22739028 Show fit	5.50	ENSMUST00000232097.2	Fetub Ensembl NCBI MGI UniProt Show fit	fetuin beta
chr9_-_118986123 Show fit	5.36	ENSMUST00000010795.5	Acaa1b Ensembl NCBI MGI UniProt Show fit	acetyl-Coenzyme A acyltransferase 1B
chr5_-_89605622 Show fit	5.27	ENSMUST00000049209.13	Gc Ensembl NCBI MGI UniProt Show fit	vitamin D binding protein
chr8_+_110717062 Show fit	5.25	ENSMUST00000001720.14 ENSMUST00000143741.2	Tat Ensembl NCBI MGI UniProt Show fit	tyrosine aminotransferase
chr9_+_46179899 Show fit	5.18	ENSMUST00000121598.8	Apoa5 Ensembl NCBI MGI UniProt Show fit	apolipoprotein A-V
chr7_-_19432308 Show fit	5.16	ENSMUST00000173739.8	Apoe Ensembl NCBI MGI UniProt Show fit	apolipoprotein E
chr17_-_35077089 Show fit	4.76	ENSMUST00000153400.8	Cfb Ensembl NCBI MGI UniProt Show fit	complement factor B
chr11_-_96807192 Show fit	4.59	ENSMUST00000144731.8 ENSMUST00000127048.8	Cdk5rap3 Ensembl NCBI MGI UniProt Show fit	CDK5 regulatory subunit associated protein 3
chr1_+_58152295 Show fit	4.56	ENSMUST00000040999.14 ENSMUST00000162011.3	Aox3 Ensembl NCBI MGI UniProt Show fit	aldehyde oxidase 3
chr17_+_24955647 Show fit	4.49	ENSMUST00000101800.7	Msrb1 Ensembl NCBI MGI UniProt Show fit	methionine sulfoxide reductase B1
chr11_-_96807273 Show fit	4.42	ENSMUST00000103152.11	Cdk5rap3 Ensembl NCBI MGI UniProt Show fit	CDK5 regulatory subunit associated protein 3
chr6_-_128503666 Show fit	4.42	ENSMUST00000143664.2 ENSMUST00000112132.8	Pzp Ensembl NCBI MGI UniProt Show fit	PZP, alpha-2-macroglobulin like
chr1_+_131725119 Show fit	3.91	ENSMUST00000112393.9 ENSMUST00000048660.12	Pm20d1 Ensembl NCBI MGI UniProt Show fit	peptidase M20 domain containing 1
chr16_+_22739191 Show fit	3.86	ENSMUST00000116625.10	Fetub Ensembl NCBI MGI UniProt Show fit	fetuin beta
chr6_+_121323577 Show fit	3.85	ENSMUST00000032200.16	Slc6a12 Ensembl NCBI MGI UniProt Show fit	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chrM_+_10167 Show fit	3.79	ENSMUST00000082414.1	mt-Nd4 Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded NADH dehydrogenase 4
chr10_-_126956991 Show fit	3.65	ENSMUST00000080975.6 ENSMUST00000164259.9	Os9 Ensembl NCBI MGI UniProt Show fit	amplified in osteosarcoma
chr11_-_70910058 Show fit	3.64	ENSMUST00000108523.10 ENSMUST00000143850.8	Derl2 Ensembl NCBI MGI UniProt Show fit	Der1-like domain family, member 2
chr11_-_96807233 Show fit	3.57	ENSMUST00000130774.2	Cdk5rap3 Ensembl NCBI MGI UniProt Show fit	CDK5 regulatory subunit associated protein 3
chr1_+_180878797 Show fit	3.48	ENSMUST00000036819.7	9130409I23Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 9130409I23 gene
chr7_-_99340830 Show fit	3.45	ENSMUST00000208713.2	Slco2b1 Ensembl NCBI MGI UniProt Show fit	solute carrier organic anion transporter family, member 2b1
chr9_-_103182246 Show fit	3.33	ENSMUST00000142540.2	1300017J02Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1300017J02 gene
chr4_+_104623505 Show fit	3.29	ENSMUST00000031663.10 ENSMUST00000065072.7	C8b Ensembl NCBI MGI UniProt Show fit	complement component 8, beta polypeptide
chr13_+_4109566 Show fit	3.27	ENSMUST00000041768.7	Akr1c14 Ensembl NCBI MGI UniProt Show fit	aldo-keto reductase family 1, member C14
chr8_-_110305672 Show fit	3.26	ENSMUST00000074898.8	Hp Ensembl NCBI MGI UniProt Show fit	haptoglobin
chr7_+_44033520 Show fit	3.26	ENSMUST00000118962.8 ENSMUST00000118831.8	Syt3 Ensembl NCBI MGI UniProt Show fit	synaptotagmin III
chr3_-_157630690 Show fit	3.25	ENSMUST00000118539.2	Cth Ensembl NCBI MGI UniProt Show fit	cystathionase (cystathionine gamma-lyase)
chr12_-_103704417 Show fit	3.24	ENSMUST00000095450.11 ENSMUST00000187220.2	Serpina1b Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) preptidase inhibitor, clade A, member 1B
chr5_-_147831610 Show fit	3.21	ENSMUST00000118527.8 ENSMUST00000031655.4 ENSMUST00000138244.2	Slc46a3 Ensembl NCBI MGI UniProt Show fit	solute carrier family 46, member 3
chr5_-_87572060 Show fit	3.11	ENSMUST00000072818.6	Ugt2b38 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B38
chr19_-_4889314 Show fit	3.07	ENSMUST00000235245.2 ENSMUST00000037246.7	Ccs Ensembl NCBI MGI UniProt Show fit	copper chaperone for superoxide dismutase
chr12_-_103829810 Show fit	3.05	ENSMUST00000085056.8 ENSMUST00000072876.12 ENSMUST00000124717.2	Serpina1a Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade A, member 1A
chr3_-_63872189 Show fit	3.05	ENSMUST00000029402.15	Slc33a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 33 (acetyl-CoA transporter), member 1
chr17_+_84990541 Show fit	3.02	ENSMUST00000045714.15 ENSMUST00000171915.2	Abcg8 Ensembl NCBI MGI UniProt Show fit	ATP binding cassette subfamily G member 8
chr9_-_26910833 Show fit	3.01	ENSMUST00000060513.8 ENSMUST00000120367.8	Acad8 Ensembl NCBI MGI UniProt Show fit	acyl-Coenzyme A dehydrogenase family, member 8
chr1_+_87998487 Show fit	2.97	ENSMUST00000073772.5	Ugt1a9 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 1 family, polypeptide A9
chr15_-_100583044 Show fit	2.95	ENSMUST00000230312.2	Cela1 Ensembl NCBI MGI UniProt Show fit	chymotrypsin-like elastase family, member 1
chr19_-_4889284 Show fit	2.94	ENSMUST00000236451.2 ENSMUST00000236178.2	Ccs Ensembl NCBI MGI UniProt Show fit	copper chaperone for superoxide dismutase
chr2_-_23939401 Show fit	2.90	ENSMUST00000051416.12	Hnmt Ensembl NCBI MGI UniProt Show fit	histamine N-methyltransferase
chr3_+_94280101 Show fit	2.73	ENSMUST00000029795.10	Rorc Ensembl NCBI MGI UniProt Show fit	RAR-related orphan receptor gamma
chr5_+_87148697 Show fit	2.72	ENSMUST00000031186.9	Ugt2b35 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B35
chr11_-_106471420 Show fit	2.69	ENSMUST00000153870.2	Tex2 Ensembl NCBI MGI UniProt Show fit	testis expressed gene 2
chr18_-_60860594 Show fit	2.68	ENSMUST00000235795.2	Ndst1 Ensembl NCBI MGI UniProt Show fit	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr11_+_69945157 Show fit	2.64	ENSMUST00000108585.9 ENSMUST00000018699.13	Asgr1 Ensembl NCBI MGI UniProt Show fit	asialoglycoprotein receptor 1
chrX_-_8059597 Show fit	2.64	ENSMUST00000143223.2 ENSMUST00000033509.15	Ebp Ensembl NCBI MGI UniProt Show fit	phenylalkylamine Ca2+ antagonist (emopamil) binding protein
chr11_+_51654511 Show fit	2.55	ENSMUST00000020653.6	Sar1b Ensembl NCBI MGI UniProt Show fit	secretion associated Ras related GTPase 1B
chr1_-_179373826 Show fit	2.55	ENSMUST00000027769.6	Tfb2m Ensembl NCBI MGI UniProt Show fit	transcription factor B2, mitochondrial
chrX_+_7588505 Show fit	2.54	ENSMUST00000207675.2 ENSMUST00000116633.9 ENSMUST00000208996.2 ENSMUST00000144148.4 ENSMUST00000125991.9 ENSMUST00000148624.8	Wdr45 Ensembl NCBI MGI UniProt Show fit	WD repeat domain 45
chr7_+_142606476 Show fit	2.50	ENSMUST00000037941.10	Cd81 Ensembl NCBI MGI UniProt Show fit	CD81 antigen
chr4_-_63072367 Show fit	2.45	ENSMUST00000030041.5	Ambp Ensembl NCBI MGI UniProt Show fit	alpha 1 microglobulin/bikunin precursor
chr4_+_62278932 Show fit	2.44	ENSMUST00000084526.12	Slc31a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 31, member 1
chr7_+_44034225 Show fit	2.42	ENSMUST00000120262.2	Syt3 Ensembl NCBI MGI UniProt Show fit	synaptotagmin III
chr6_-_124718316 Show fit	2.41	ENSMUST00000004389.6	Grcc10 Ensembl NCBI MGI UniProt Show fit	gene rich cluster, C10 gene
chr12_-_103923145 Show fit	2.39	ENSMUST00000085054.5	Serpina1e Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade A, member 1E
chr1_+_16758629 Show fit	2.38	ENSMUST00000026881.11	Ly96 Ensembl NCBI MGI UniProt Show fit	lymphocyte antigen 96
chrX_+_7588453 Show fit	2.37	ENSMUST00000043045.10 ENSMUST00000207386.2 ENSMUST00000116634.9 ENSMUST00000208072.2 ENSMUST00000207589.2 ENSMUST00000208618.2 ENSMUST00000208443.2 ENSMUST00000207541.2 ENSMUST00000208528.2 ENSMUST00000115689.10 ENSMUST00000131077.9 ENSMUST00000115688.8 ENSMUST00000208156.2	Wdr45 Ensembl NCBI MGI UniProt Show fit Gm45208 Ensembl NCBI MGI UniProt Show fit	WD repeat domain 45 predicted gene 45208
chr9_+_103940575 Show fit	2.32	ENSMUST00000120854.8	Acad11 Ensembl NCBI MGI UniProt Show fit	acyl-Coenzyme A dehydrogenase family, member 11
chr1_+_88128323 Show fit	2.30	ENSMUST00000049289.9	Ugt1a2 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 1 family, polypeptide A2
chrX_+_100420873 Show fit	2.27	ENSMUST00000052130.14	Gjb1 Ensembl NCBI MGI UniProt Show fit	gap junction protein, beta 1
chr2_-_84605732 Show fit	2.25	ENSMUST00000023994.10	Serping1 Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade G, member 1
chr11_+_73090270 Show fit	2.23	ENSMUST00000006105.7	Shpk Ensembl NCBI MGI UniProt Show fit	sedoheptulokinase
chr2_-_84605764 Show fit	2.22	ENSMUST00000111641.2	Serping1 Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade G, member 1
chr1_+_107289659 Show fit	2.17	ENSMUST00000027566.3	Serpinb11 Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr7_+_130633776 Show fit	2.17	ENSMUST00000084509.7 ENSMUST00000213064.3 ENSMUST00000208311.4	Dmbt1 Ensembl NCBI MGI UniProt Show fit	deleted in malignant brain tumors 1
chr10_+_80165787 Show fit	2.15	ENSMUST00000105358.8 ENSMUST00000105357.2 ENSMUST00000105354.8 ENSMUST00000105355.8	Reep6 Ensembl NCBI MGI UniProt Show fit	receptor accessory protein 6
chr9_-_50657800 Show fit	2.14	ENSMUST00000239417.2 ENSMUST00000034564.4	2310030G06Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2310030G06 gene
chrX_+_100427331 Show fit	2.13	ENSMUST00000119190.2	Gjb1 Ensembl NCBI MGI UniProt Show fit	gap junction protein, beta 1
chr18_+_50261268 Show fit	2.11	ENSMUST00000025385.7	Hsd17b4 Ensembl NCBI MGI UniProt Show fit	hydroxysteroid (17-beta) dehydrogenase 4
chr5_+_3646066 Show fit	2.08	ENSMUST00000006061.13 ENSMUST00000121291.8 ENSMUST00000142516.2	Pex1 Ensembl NCBI MGI UniProt Show fit	peroxisomal biogenesis factor 1
chr9_-_100916946 Show fit	2.07	ENSMUST00000035116.12	Pccb Ensembl NCBI MGI UniProt Show fit	propionyl Coenzyme A carboxylase, beta polypeptide
chr6_+_88701810 Show fit	2.02	ENSMUST00000089449.5	Mgll Ensembl NCBI MGI UniProt Show fit	monoglyceride lipase
chr18_-_56695333 Show fit	2.02	ENSMUST00000066208.13 ENSMUST00000172734.8	Aldh7a1 Ensembl NCBI MGI UniProt Show fit	aldehyde dehydrogenase family 7, member A1
chr3_-_89186940 Show fit	2.01	ENSMUST00000118860.2 ENSMUST00000029566.9	Efna1 Ensembl NCBI MGI UniProt Show fit	ephrin A1
chrX_+_141011173 Show fit	2.01	ENSMUST00000112914.8	Nxt2 Ensembl NCBI MGI UniProt Show fit	nuclear transport factor 2-like export factor 2
chr1_+_16758731 Show fit	2.00	ENSMUST00000190366.2	Ly96 Ensembl NCBI MGI UniProt Show fit	lymphocyte antigen 96
chr5_-_87686048 Show fit	2.00	ENSMUST00000031199.11	Sult1b1 Ensembl NCBI MGI UniProt Show fit	sulfotransferase family 1B, member 1
chr9_-_100916910 Show fit	2.00	ENSMUST00000142676.8 ENSMUST00000149322.8 ENSMUST00000189498.2	Pccb Ensembl NCBI MGI UniProt Show fit	propionyl Coenzyme A carboxylase, beta polypeptide
chr2_-_165997551 Show fit	1.99	ENSMUST00000109249.9 ENSMUST00000146497.9	Sulf2 Ensembl NCBI MGI UniProt Show fit	sulfatase 2
chr2_-_165997179 Show fit	1.99	ENSMUST00000088086.4	Sulf2 Ensembl NCBI MGI UniProt Show fit	sulfatase 2
chr4_+_43493344 Show fit	1.97	ENSMUST00000030181.12 ENSMUST00000107922.3	Ccdc107 Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 107
chr7_+_44240310 Show fit	1.95	ENSMUST00000107906.6	Kcnc3 Ensembl NCBI MGI UniProt Show fit	potassium voltage gated channel, Shaw-related subfamily, member 3
chr16_+_70110837 Show fit	1.93	ENSMUST00000163832.8	Gbe1 Ensembl NCBI MGI UniProt Show fit	glucan (1,4-alpha-), branching enzyme 1
chr13_+_93810911 Show fit	1.93	ENSMUST00000048001.8	Dmgdh Ensembl NCBI MGI UniProt Show fit	dimethylglycine dehydrogenase precursor
chr15_+_88703786 Show fit	1.92	ENSMUST00000024042.5	Creld2 Ensembl NCBI MGI UniProt Show fit	cysteine-rich with EGF-like domains 2
chr14_-_118370144 Show fit	1.90	ENSMUST00000022727.10 ENSMUST00000228543.2	Tgds Ensembl NCBI MGI UniProt Show fit	TDP-glucose 4,6-dehydratase
chrX_+_150784841 Show fit	1.88	ENSMUST00000026289.10 ENSMUST00000112617.4	Hsd17b10 Ensembl NCBI MGI UniProt Show fit	hydroxysteroid (17-beta) dehydrogenase 10
chr1_-_162726234 Show fit	1.88	ENSMUST00000111510.8 ENSMUST00000045902.13	Fmo2 Ensembl NCBI MGI UniProt Show fit	flavin containing monooxygenase 2
chr11_-_106378622 Show fit	1.87	ENSMUST00000001059.9 ENSMUST00000106799.2 ENSMUST00000106800.2	Ern1 Ensembl NCBI MGI UniProt Show fit	endoplasmic reticulum (ER) to nucleus signalling 1
chr7_+_29883611 Show fit	1.83	ENSMUST00000208441.2	Cox7a1 Ensembl NCBI MGI UniProt Show fit	cytochrome c oxidase subunit 7A1
chrM_+_9870 Show fit	1.82	ENSMUST00000084013.1	mt-Nd4l Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded NADH dehydrogenase 4L
chr6_+_78402956 Show fit	1.81	ENSMUST00000079926.6	Reg1 Ensembl NCBI MGI UniProt Show fit	regenerating islet-derived 1
chr2_+_151947444 Show fit	1.80	ENSMUST00000041500.8	Srxn1 Ensembl NCBI MGI UniProt Show fit	sulfiredoxin 1 homolog (S. cerevisiae)
chr10_+_80165961 Show fit	1.78	ENSMUST00000186864.7 ENSMUST00000040081.7	Reep6 Ensembl NCBI MGI UniProt Show fit	receptor accessory protein 6
chr17_+_31652029 Show fit	1.78	ENSMUST00000136384.9	Pde9a Ensembl NCBI MGI UniProt Show fit	phosphodiesterase 9A
chr14_+_69409251 Show fit	1.76	ENSMUST00000062437.10	Nkx2-6 Ensembl NCBI MGI UniProt Show fit	NK2 homeobox 6
chr19_+_38469504 Show fit	1.74	ENSMUST00000182481.8	Plce1 Ensembl NCBI MGI UniProt Show fit	phospholipase C, epsilon 1
chr16_+_22676589 Show fit	1.73	ENSMUST00000004574.14 ENSMUST00000178320.2 ENSMUST00000166487.10	Dnajb11 Ensembl NCBI MGI UniProt Show fit	DnaJ heat shock protein family (Hsp40) member B11
chr13_-_34314328 Show fit	1.72	ENSMUST00000075774.5	Tubb2b Ensembl NCBI MGI UniProt Show fit	tubulin, beta 2B class IIB
chr3_-_89009214 Show fit	1.72	ENSMUST00000081848.13	Fdps Ensembl NCBI MGI UniProt Show fit	farnesyl diphosphate synthetase
chr3_-_63872079 Show fit	1.71	ENSMUST00000161659.8	Slc33a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 33 (acetyl-CoA transporter), member 1
chr14_+_118374511 Show fit	1.70	ENSMUST00000022728.4	Gpr180 Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 180
chr3_-_88204286 Show fit	1.70	ENSMUST00000107556.10	Tsacc Ensembl NCBI MGI UniProt Show fit	TSSK6 activating co-chaperone
chr11_-_60243695 Show fit	1.69	ENSMUST00000095254.12 ENSMUST00000102683.11 ENSMUST00000093048.13 ENSMUST00000093046.13 ENSMUST00000064019.15 ENSMUST00000102682.5	Tom1l2 Ensembl NCBI MGI UniProt Show fit	target of myb1-like 2 (chicken)
chr3_-_88204145 Show fit	1.68	ENSMUST00000010682.4	Tsacc Ensembl NCBI MGI UniProt Show fit	TSSK6 activating co-chaperone
chr11_-_82655132 Show fit	1.68	ENSMUST00000021040.10 ENSMUST00000100722.5	Cct6b Ensembl NCBI MGI UniProt Show fit	chaperonin containing Tcp1, subunit 6b (zeta)
chr3_-_89009153 Show fit	1.64	ENSMUST00000199668.3 ENSMUST00000196709.5	Fdps Ensembl NCBI MGI UniProt Show fit	farnesyl diphosphate synthetase
chr3_-_113198765 Show fit	1.61	ENSMUST00000179568.3	Amy2a4 Ensembl NCBI MGI UniProt Show fit	amylase 2a4
chr16_-_90731394 Show fit	1.60	ENSMUST00000142340.2	Cfap298 Ensembl NCBI MGI UniProt Show fit	cilia and flagella associate protien 298
chr8_-_78337226 Show fit	1.60	ENSMUST00000034030.15	Tmem184c Ensembl NCBI MGI UniProt Show fit	transmembrane protein 184C
chr7_-_140462187 Show fit	1.60	ENSMUST00000211179.2	Sirt3 Ensembl NCBI MGI UniProt Show fit	sirtuin 3
chr12_-_112905721 Show fit	1.59	ENSMUST00000221497.2 ENSMUST00000002881.5 ENSMUST00000221397.2	Nudt14 Ensembl NCBI MGI UniProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr13_-_67081138 Show fit	1.59	ENSMUST00000021991.11	Mterf3 Ensembl NCBI MGI UniProt Show fit	mitochondrial transcription termination factor 3
chr10_-_24587884 Show fit	1.58	ENSMUST00000135846.2	Enpp1 Ensembl NCBI MGI UniProt Show fit	ectonucleotide pyrophosphatase/phosphodiesterase 1
chrX_+_141010919 Show fit	1.57	ENSMUST00000042329.12	Nxt2 Ensembl NCBI MGI UniProt Show fit	nuclear transport factor 2-like export factor 2
chr19_+_46587523 Show fit	1.56	ENSMUST00000138302.9 ENSMUST00000099376.11	Wbp1l Ensembl NCBI MGI UniProt Show fit	WW domain binding protein 1 like
chr7_-_140462221 Show fit	1.56	ENSMUST00000026559.14	Sirt3 Ensembl NCBI MGI UniProt Show fit	sirtuin 3
chr11_-_50216426 Show fit	1.55	ENSMUST00000179865.8 ENSMUST00000020637.9	Canx Ensembl NCBI MGI UniProt Show fit	calnexin
chr13_-_67080968 Show fit	1.53	ENSMUST00000172597.8 ENSMUST00000173773.2	Mterf3 Ensembl NCBI MGI UniProt Show fit	mitochondrial transcription termination factor 3
chr7_+_16186704 Show fit	1.51	ENSMUST00000019302.10	Tmem160 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 160
chr8_+_11547506 Show fit	1.50	ENSMUST00000177955.8 ENSMUST00000033901.11 ENSMUST00000178721.2	Naxd Ensembl NCBI MGI UniProt Show fit	NAD(P)HX dehydratase
chr3_-_116388334 Show fit	1.50	ENSMUST00000197190.5 ENSMUST00000198454.2	Trmt13 Ensembl NCBI MGI UniProt Show fit	tRNA methyltransferase 13
chr16_+_29398149 Show fit	1.47	ENSMUST00000160597.8	Opa1 Ensembl NCBI MGI UniProt Show fit	OPA1, mitochondrial dynamin like GTPase
chr14_-_25769457 Show fit	1.47	ENSMUST00000069180.8	Zcchc24 Ensembl NCBI MGI UniProt Show fit	zinc finger, CCHC domain containing 24
chr16_+_29398165 Show fit	1.46	ENSMUST00000161186.8 ENSMUST00000038867.13	Opa1 Ensembl NCBI MGI UniProt Show fit	OPA1, mitochondrial dynamin like GTPase
chr15_-_11399666 Show fit	1.45	ENSMUST00000022849.7	Tars Ensembl NCBI MGI UniProt Show fit	threonyl-tRNA synthetase
chr7_+_4240697 Show fit	1.45	ENSMUST00000117550.2	Lilra5 Ensembl NCBI MGI UniProt Show fit	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr11_-_59937302 Show fit	1.44	ENSMUST00000000310.14 ENSMUST00000102693.9 ENSMUST00000148512.2	Pemt Ensembl NCBI MGI UniProt Show fit	phosphatidylethanolamine N-methyltransferase
chr3_+_63202687 Show fit	1.44	ENSMUST00000194836.6 ENSMUST00000191633.6	Mme Ensembl NCBI MGI UniProt Show fit	membrane metallo endopeptidase
chr11_-_53313950 Show fit	1.44	ENSMUST00000036045.6	Leap2 Ensembl NCBI MGI UniProt Show fit	liver-expressed antimicrobial peptide 2
chr3_+_20011201 Show fit	1.43	ENSMUST00000091309.12 ENSMUST00000108329.8 ENSMUST00000003714.13	Cp Ensembl NCBI MGI UniProt Show fit	ceruloplasmin
chrM_+_3906 Show fit	1.43	ENSMUST00000082396.1	mt-Nd2 Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded NADH dehydrogenase 2
chr6_-_24527545 Show fit	1.41	ENSMUST00000118558.5	Ndufa5 Ensembl NCBI MGI UniProt Show fit	NADH:ubiquinone oxidoreductase subunit A5
chr16_+_96162854 Show fit	1.41	ENSMUST00000113794.8	Igsf5 Ensembl NCBI MGI UniProt Show fit	immunoglobulin superfamily, member 5
chr8_-_78337297 Show fit	1.41	ENSMUST00000141202.2 ENSMUST00000152168.8	Tmem184c Ensembl NCBI MGI UniProt Show fit	transmembrane protein 184C
chr10_-_71180763 Show fit	1.41	ENSMUST00000045887.9	Cisd1 Ensembl NCBI MGI UniProt Show fit	CDGSH iron sulfur domain 1
chr15_-_89263790 Show fit	1.40	ENSMUST00000238996.2	Odf3b Ensembl NCBI MGI UniProt Show fit	outer dense fiber of sperm tails 3B
chr2_-_165996716 Show fit	1.40	ENSMUST00000139266.2	Sulf2 Ensembl NCBI MGI UniProt Show fit	sulfatase 2
chr11_-_95966407 Show fit	1.40	ENSMUST00000107686.8 ENSMUST00000107684.2	Atp5g1 Ensembl NCBI MGI UniProt Show fit	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
chr6_-_88021999 Show fit	1.40	ENSMUST00000113598.8	Rab7 Ensembl NCBI MGI UniProt Show fit	RAB7, member RAS oncogene family
chr7_-_137012444 Show fit	1.39	ENSMUST00000120340.2 ENSMUST00000117404.8 ENSMUST00000068996.13	9430038I01Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 9430038I01 gene
chr2_-_130506484 Show fit	1.39	ENSMUST00000089559.11	Ddrgk1 Ensembl NCBI MGI UniProt Show fit	DDRGK domain containing 1
chr16_+_34842764 Show fit	1.38	ENSMUST00000061156.10	Hacd2 Ensembl NCBI MGI UniProt Show fit	3-hydroxyacyl-CoA dehydratase 2
chr1_+_172525613 Show fit	1.38	ENSMUST00000038495.5	Crp Ensembl NCBI MGI UniProt Show fit	C-reactive protein, pentraxin-related
chr3_-_113166153 Show fit	1.38	ENSMUST00000098673.5	Amy2a5 Ensembl NCBI MGI UniProt Show fit	amylase 2a5
chr14_-_9184969 Show fit	1.37	ENSMUST00000070323.12	Synpr Ensembl NCBI MGI UniProt Show fit	synaptoporin
chr16_-_90731611 Show fit	1.36	ENSMUST00000149833.8	Cfap298 Ensembl NCBI MGI UniProt Show fit	cilia and flagella associate protien 298
chr11_-_120604551 Show fit	1.35	ENSMUST00000106154.8 ENSMUST00000106155.4 ENSMUST00000055424.13 ENSMUST00000026137.8	Cenpx Ensembl NCBI MGI UniProt Show fit	centromere protein X
chr9_-_56835633 Show fit	1.34	ENSMUST00000050916.7	Snx33 Ensembl NCBI MGI UniProt Show fit	sorting nexin 33
chr1_+_171173237 Show fit	1.33	ENSMUST00000135941.8	Pfdn2 Ensembl NCBI MGI UniProt Show fit	prefoldin 2
chr12_+_103498542 Show fit	1.33	ENSMUST00000021631.12	Ppp4r4 Ensembl NCBI MGI UniProt Show fit	protein phosphatase 4, regulatory subunit 4
chr7_-_27373939 Show fit	1.33	ENSMUST00000138243.2	Map3k10 Ensembl NCBI MGI UniProt Show fit	mitogen-activated protein kinase kinase kinase 10
chr6_+_30639217 Show fit	1.32	ENSMUST00000031806.10	Cpa1 Ensembl NCBI MGI UniProt Show fit	carboxypeptidase A1, pancreatic
chr5_-_91550853 Show fit	1.31	ENSMUST00000121044.6	Btc Ensembl NCBI MGI UniProt Show fit	betacellulin, epidermal growth factor family member
chr17_-_35265514 Show fit	1.31	ENSMUST00000007250.14	Msh5 Ensembl NCBI MGI UniProt Show fit	mutS homolog 5
chr3_+_20011251 Show fit	1.30	ENSMUST00000108328.8	Cp Ensembl NCBI MGI UniProt Show fit	ceruloplasmin
chr3_-_58433313 Show fit	1.30	ENSMUST00000029385.9	Serp1 Ensembl NCBI MGI UniProt Show fit	stress-associated endoplasmic reticulum protein 1
chr8_-_3767547 Show fit	1.29	ENSMUST00000058040.7	Clec4g Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 4, member g
chr19_+_45064539 Show fit	1.28	ENSMUST00000026234.5	Kazald1 Ensembl NCBI MGI UniProt Show fit	Kazal-type serine peptidase inhibitor domain 1
chrX_-_100838004 Show fit	1.28	ENSMUST00000147742.9	Gm4779 Ensembl NCBI MGI UniProt Show fit	predicted gene 4779
chr10_-_17898838 Show fit	1.27	ENSMUST00000220433.2	Abracl Ensembl NCBI MGI UniProt Show fit	ABRA C-terminal like
chr10_+_79505203 Show fit	1.25	ENSMUST00000020552.8 ENSMUST00000239401.2	Tpgs1 Ensembl NCBI MGI UniProt Show fit	tubulin polyglutamylase complex subunit 1
chr1_-_183078488 Show fit	1.24	ENSMUST00000057062.12	Brox Ensembl NCBI MGI UniProt Show fit	BRO1 domain and CAAX motif containing
chr9_-_108911438 Show fit	1.23	ENSMUST00000192801.2	Tma7 Ensembl NCBI MGI UniProt Show fit	translational machinery associated 7
chr13_+_67080864 Show fit	1.23	ENSMUST00000021990.4	Ptdss1 Ensembl NCBI MGI UniProt Show fit	phosphatidylserine synthase 1
chr17_-_33979280 Show fit	1.23	ENSMUST00000173860.8	Rab11b Ensembl NCBI MGI UniProt Show fit	RAB11B, member RAS oncogene family
chr18_-_68433398 Show fit	1.22	ENSMUST00000042852.7	Fam210a Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 210, member A
chr2_+_15060051 Show fit	1.22	ENSMUST00000069870.11 ENSMUST00000239125.2 ENSMUST00000193836.3	Arl5b Ensembl NCBI MGI UniProt Show fit	ADP-ribosylation factor-like 5B
chr4_+_41465134 Show fit	1.22	ENSMUST00000030154.7	Nudt2 Ensembl NCBI MGI UniProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 2
chr5_+_54155814 Show fit	1.22	ENSMUST00000117661.9	Stim2 Ensembl NCBI MGI UniProt Show fit	stromal interaction molecule 2
chr5_+_3646355 Show fit	1.21	ENSMUST00000195894.2	Pex1 Ensembl NCBI MGI UniProt Show fit	peroxisomal biogenesis factor 1
chr10_+_62897353 Show fit	1.20	ENSMUST00000178684.3 ENSMUST00000020266.15	Pbld1 Ensembl NCBI MGI UniProt Show fit	phenazine biosynthesis-like protein domain containing 1
chr19_+_43770619 Show fit	1.19	ENSMUST00000026208.6	Abcc2 Ensembl NCBI MGI UniProt Show fit	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr4_-_91288221 Show fit	1.19	ENSMUST00000102799.10	Elavl2 Ensembl NCBI MGI UniProt Show fit	ELAV like RNA binding protein 1
chr9_+_46151994 Show fit	1.18	ENSMUST00000034585.7	Apoa4 Ensembl NCBI MGI UniProt Show fit	apolipoprotein A-IV
chr6_+_95094721 Show fit	1.18	ENSMUST00000032107.10 ENSMUST00000119582.3	Kbtbd8 Ensembl NCBI MGI UniProt Show fit	kelch repeat and BTB (POZ) domain containing 8
chr1_-_78488795 Show fit	1.18	ENSMUST00000170511.3	BC035947 Ensembl NCBI MGI UniProt Show fit	cDNA sequence BC035947
chrM_+_7006 Show fit	1.17	ENSMUST00000082405.1	mt-Co2 Ensembl NCBI MGI UniProt Show fit	mitochondrially encoded cytochrome c oxidase II
chrX_+_100419965 Show fit	1.13	ENSMUST00000119080.8	Gjb1 Ensembl NCBI MGI UniProt Show fit	gap junction protein, beta 1
chr3_+_144276154 Show fit	1.13	ENSMUST00000082437.11	Selenof Ensembl NCBI MGI UniProt Show fit	selenoprotein F
chr11_-_76969230 Show fit	1.13	ENSMUST00000102494.8	Nsrp1 Ensembl NCBI MGI UniProt Show fit	nuclear speckle regulatory protein 1
chr5_+_54155871 Show fit	1.13	ENSMUST00000201469.4	Stim2 Ensembl NCBI MGI UniProt Show fit	stromal interaction molecule 2
chr11_-_3881995 Show fit	1.12	ENSMUST00000020710.11 ENSMUST00000109989.10 ENSMUST00000109991.8 ENSMUST00000109993.9	Tcn2 Ensembl NCBI MGI UniProt Show fit	transcobalamin 2
chr6_-_128415640 Show fit	1.12	ENSMUST00000032508.11	Fkbp4 Ensembl NCBI MGI UniProt Show fit	FK506 binding protein 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Cux1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.7	17.1	GO:1903699	tarsal gland development(GO:1903699)
5.3	26.7	GO:0071718	sodium-independent icosanoid transport(GO:0071718)
2.6	7.9	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
2.6	10.4	GO:0030091	protein repair(GO:0030091)
2.6	7.7	GO:0090420	naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
1.7	14.0	GO:0071569	protein ufmylation(GO:0071569)
1.7	5.2	GO:1903000	regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
1.5	18.1	GO:0043651	linoleic acid metabolic process(GO:0043651)
1.5	4.5	GO:0001869	regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.3	5.2	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
1.2	1.2	GO:0050787	detoxification of mercury ion(GO:0050787)
1.1	3.3	GO:0060152	peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
1.1	3.3	GO:2000295	regulation of hydrogen peroxide catabolic process(GO:2000295)
0.9	4.6	GO:0009115	xanthine catabolic process(GO:0009115)
0.9	5.4	GO:0014846	esophagus smooth muscle contraction(GO:0014846)
0.8	2.5	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.8	3.4	GO:0045338	farnesyl diphosphate metabolic process(GO:0045338)
0.8	3.3	GO:0019343	cysteine biosynthetic process via cystathionine(GO:0019343)
0.8	3.9	GO:0009992	cellular water homeostasis(GO:0009992)
0.7	4.2	GO:0030300	regulation of intestinal cholesterol absorption(GO:0030300)
0.7	18.6	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.7	2.0	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
0.7	7.3	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.6	4.4	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.6	2.9	GO:0010636	positive regulation of mitochondrial fusion(GO:0010636)
0.6	5.3	GO:0006572	tyrosine catabolic process(GO:0006572)
0.6	2.9	GO:0001692	histamine metabolic process(GO:0001692)
0.6	1.2	GO:1902958	neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.6	5.8	GO:0097421	liver regeneration(GO:0097421)
0.6	3.9	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.6	2.2	GO:0035962	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.5	5.5	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.5	2.5	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.5	7.3	GO:0009812	flavonoid metabolic process(GO:0009812)
0.5	1.9	GO:1903542	negative regulation of exosomal secretion(GO:1903542)
0.5	2.4	GO:0036343	psychomotor behavior(GO:0036343)
0.5	8.0	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.5	2.8	GO:0072592	oxygen metabolic process(GO:0072592)
0.4	1.8	GO:0055014	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.4	2.9	GO:0060309	elastin catabolic process(GO:0060309)
0.4	2.8	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987) mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.4	2.0	GO:0014028	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) notochord formation(GO:0014028)
0.4	1.2	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.4	1.2	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.4	1.4	GO:0060912	cardiac cell fate specification(GO:0060912)
0.4	2.1	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.3	2.4	GO:0098705	copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.3	2.0	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.3	1.3	GO:0080163	regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.3	1.0	GO:0042231	interleukin-13 biosynthetic process(GO:0042231)
0.3	1.0	GO:0042853	glycine biosynthetic process, by transamination of glyoxylate(GO:0019265) L-alanine catabolic process(GO:0042853) oxalic acid secretion(GO:0046724)
0.3	4.2	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.3	0.9	GO:1902868	cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.3	4.9	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.3	0.9	GO:0035627	ceramide transport(GO:0035627)
0.3	2.7	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3	2.3	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.3	0.9	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.3	1.4	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.3	0.8	GO:0016132	brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132)
0.3	0.8	GO:0090650	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.3	0.8	GO:1900275	negative regulation of phospholipase C activity(GO:1900275)
0.3	0.8	GO:1904155	DN2 thymocyte differentiation(GO:1904155) DN3 thymocyte differentiation(GO:1904156)
0.2	2.7	GO:0072615	interleukin-17 secretion(GO:0072615)
0.2	1.2	GO:0045054	constitutive secretory pathway(GO:0045054)
0.2	4.5	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.2	0.7	GO:0060133	somatotropin secreting cell development(GO:0060133)
0.2	0.9	GO:1905154	negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.2	0.9	GO:0097032	respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2	0.9	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.2	0.6	GO:0001788	antibody-dependent cellular cytotoxicity(GO:0001788)
0.2	1.9	GO:0019695	choline metabolic process(GO:0019695)
0.2	4.5	GO:0042359	vitamin D metabolic process(GO:0042359)
0.2	2.9	GO:0035092	sperm chromatin condensation(GO:0035092)
0.2	1.4	GO:0071492	cellular response to UV-A(GO:0071492)
0.2	0.6	GO:0040040	thermosensory behavior(GO:0040040)
0.2	8.5	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.2	0.6	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.2	0.4	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2	1.1	GO:0015889	cobalamin transport(GO:0015889)
0.2	0.7	GO:1900110	negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.2	1.1	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.2	1.6	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.2	1.4	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.2	1.7	GO:1902669	positive regulation of axon guidance(GO:1902669)
0.2	1.3	GO:0036089	cleavage furrow formation(GO:0036089)
0.2	0.5	GO:2000845	negative regulation of glucagon secretion(GO:0070093) positive regulation of testosterone secretion(GO:2000845)
0.2	0.5	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
0.2	1.1	GO:0036476	neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.2	8.4	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.2	0.6	GO:0061511	centriole elongation(GO:0061511)
0.2	1.1	GO:0072092	ureteric bud invasion(GO:0072092)
0.1	0.7	GO:0070494	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1	3.0	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.1	4.8	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1	3.9	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1	0.6	GO:0072061	establishment or maintenance of polarity of embryonic epithelium(GO:0016332) inner medullary collecting duct development(GO:0072061)
0.1	1.1	GO:0070417	cellular response to cold(GO:0070417)
0.1	2.0	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.4	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1	4.0	GO:0006825	copper ion transport(GO:0006825)
0.1	1.0	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.1	1.0	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1	0.5	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1	0.4	GO:1902623	negative regulation of neutrophil migration(GO:1902623)
0.1	0.6	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.1	0.6	GO:0051684	maintenance of Golgi location(GO:0051684)
0.1	0.4	GO:0090076	relaxation of skeletal muscle(GO:0090076)
0.1	0.5	GO:1901162	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1	1.3	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.1	0.3	GO:1904328	regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1	0.6	GO:0001951	intestinal D-glucose absorption(GO:0001951)
0.1	0.6	GO:0006538	glutamate catabolic process(GO:0006538)
0.1	1.6	GO:0018298	protein-chromophore linkage(GO:0018298)
0.1	0.5	GO:0072362	regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1	0.5	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1	0.5	GO:0032917	polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1	1.3	GO:0051026	chiasma assembly(GO:0051026)
0.1	0.8	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	0.8	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	2.3	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1	1.2	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1	1.2	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	1.3	GO:0035810	positive regulation of urine volume(GO:0035810)
0.1	4.1	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.1	6.0	GO:0022904	respiratory electron transport chain(GO:0022904)
0.1	0.3	GO:0048372	neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) positive regulation of cardiac ventricle development(GO:1904414)
0.1	1.5	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.7	GO:0051715	cytolysis in other organism(GO:0051715)
0.1	0.4	GO:0090669	telomerase RNA stabilization(GO:0090669)
0.1	1.8	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	0.2	GO:0001806	type IV hypersensitivity(GO:0001806)
0.1	0.6	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	1.0	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1	0.3	GO:2000588	positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.1	0.5	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1	0.8	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1	1.0	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.1	0.6	GO:0098700	neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1	0.3	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.1	5.6	GO:0009062	fatty acid catabolic process(GO:0009062)
0.1	0.2	GO:2000016	negative regulation of determination of dorsal identity(GO:2000016)
0.1	0.5	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1	1.3	GO:0034587	piRNA metabolic process(GO:0034587)
0.1	0.9	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1	4.0	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.1	1.3	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	1.5	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	0.2	GO:0009240	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.1	0.6	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1	0.8	GO:0042407	cristae formation(GO:0042407)
0.1	0.7	GO:2001028	positive regulation of endothelial cell chemotaxis(GO:2001028)
0.1	1.7	GO:0016556	mRNA modification(GO:0016556)
0.1	1.6	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	1.4	GO:0042761	fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.1	2.6	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1	0.3	GO:0035106	operant conditioning(GO:0035106)
0.1	6.2	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.1	0.5	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.1	1.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.1	0.7	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1	1.7	GO:0006458	'de novo' protein folding(GO:0006458)
0.1	1.4	GO:0043457	regulation of cellular respiration(GO:0043457)
0.1	0.3	GO:0046878	positive regulation of saliva secretion(GO:0046878)
0.0	0.3	GO:0021650	vestibulocochlear nerve formation(GO:0021650)
0.0	0.2	GO:1902310	positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0	0.2	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0	0.1	GO:0036269	swimming behavior(GO:0036269)
0.0	0.2	GO:0010578	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0	0.3	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.7	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.4	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0	0.8	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.1	GO:0033693	peripheral nervous system axon regeneration(GO:0014012) neurofilament bundle assembly(GO:0033693)
0.0	0.6	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.0	8.8	GO:0006694	steroid biosynthetic process(GO:0006694)
0.0	0.8	GO:0044331	cell-cell adhesion mediated by cadherin(GO:0044331)
0.0	0.3	GO:0036394	amylase secretion(GO:0036394)
0.0	0.5	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.1	GO:0043060	meiotic metaphase I plate congression(GO:0043060) meiotic metaphase plate congression(GO:0051311)
0.0	0.6	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.7	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.0	0.1	GO:1904092	regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
0.0	0.3	GO:0060460	left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
0.0	2.3	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.5	GO:0046037	GMP metabolic process(GO:0046037)
0.0	0.3	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.0	0.8	GO:0034063	stress granule assembly(GO:0034063)
0.0	3.7	GO:0019236	response to pheromone(GO:0019236)
0.0	0.9	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.4	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.0	1.4	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	8.7	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.0	0.3	GO:0021842	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0	0.5	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.2	GO:0014717	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0	0.6	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.2	GO:0042446	hormone biosynthetic process(GO:0042446)
0.0	0.4	GO:0002827	positive regulation of T-helper 1 type immune response(GO:0002827)
0.0	0.8	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.5	GO:0010225	response to UV-C(GO:0010225)
0.0	0.2	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.4	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	1.1	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	2.0	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.5	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.3	GO:0060253	negative regulation of glial cell proliferation(GO:0060253)
0.0	0.4	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.2	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.6	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.2	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0	0.4	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.5	GO:0023019	signal transduction involved in regulation of gene expression(GO:0023019)
0.0	0.9	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968)
0.0	0.4	GO:0060539	diaphragm development(GO:0060539)
0.0	0.9	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.0	1.7	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	1.6	GO:0060395	SMAD protein signal transduction(GO:0060395)
0.0	0.6	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	1.7	GO:0032835	glomerulus development(GO:0032835)
0.0	0.6	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.7	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.3	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	1.5	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.0	0.5	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.0	0.1	GO:0098912	membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0	0.7	GO:0009409	response to cold(GO:0009409)
0.0	0.2	GO:0015747	urate transport(GO:0015747)
0.0	0.8	GO:0001881	receptor recycling(GO:0001881)
0.0	0.2	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.2	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0	0.3	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	0.5	GO:0031424	keratinization(GO:0031424)
0.0	1.7	GO:0006457	protein folding(GO:0006457)
0.0	0.1	GO:0022601	menstrual cycle phase(GO:0022601)
0.0	0.2	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.2	GO:0045794	negative regulation of cell volume(GO:0045794)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.3	GO:0035634	response to stilbenoid(GO:0035634)
0.0	0.7	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839)
0.0	0.4	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0	0.9	GO:0014032	neural crest cell development(GO:0014032)
0.0	1.5	GO:0014013	regulation of gliogenesis(GO:0014013)
0.0	0.5	GO:0007628	adult walking behavior(GO:0007628)
0.0	0.1	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.0	GO:0002355	detection of tumor cell(GO:0002355)
0.0	0.3	GO:0051646	mitochondrion localization(GO:0051646)
0.0	1.0	GO:0051289	protein homotetramerization(GO:0051289)
0.0	0.2	GO:0045187	regulation of circadian sleep/wake cycle, sleep(GO:0045187)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	3.9	GO:0044317	rod spherule(GO:0044317)
1.0	5.2	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.9	2.8	GO:1990630	IRE1-RACK1-PP2A complex(GO:1990630)
0.5	4.4	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.5	5.8	GO:0005796	Golgi lumen(GO:0005796)
0.5	3.6	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.5	2.9	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.5	3.7	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.4	3.3	GO:0005579	membrane attack complex(GO:0005579)
0.4	6.5	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.3	4.8	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.3	27.1	GO:0009925	basal plasma membrane(GO:0009925)
0.3	2.7	GO:0070552	BRISC complex(GO:0070552)
0.2	6.1	GO:0005922	connexon complex(GO:0005922)
0.2	0.7	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.2	1.6	GO:0097441	basilar dendrite(GO:0097441)
0.2	0.6	GO:0030312	external encapsulating structure(GO:0030312)
0.2	0.9	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2	3.6	GO:0042627	chylomicron(GO:0042627)
0.2	0.6	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.2	0.7	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.2	2.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.2	0.8	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2	0.6	GO:0044316	cone cell pedicle(GO:0044316)
0.1	0.7	GO:0005640	nuclear outer membrane(GO:0005640)
0.1	1.6	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.1	13.7	GO:0070469	respiratory chain(GO:0070469)
0.1	0.5	GO:1990415	Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1	1.3	GO:0016272	prefoldin complex(GO:0016272)
0.1	1.7	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	1.7	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533)
0.1	1.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.1	18.8	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	0.8	GO:0033647	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.1	0.7	GO:0072487	MSL complex(GO:0072487)
0.1	9.7	GO:0005811	lipid particle(GO:0005811)
0.1	5.3	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	0.8	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1	5.8	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	4.6	GO:0032809	neuronal cell body membrane(GO:0032809)
0.1	1.0	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	0.2	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.1	17.6	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	2.0	GO:0043196	varicosity(GO:0043196)
0.1	0.6	GO:0061617	MICOS complex(GO:0061617)
0.1	0.9	GO:0032009	early phagosome(GO:0032009)
0.1	0.9	GO:0036156	inner dynein arm(GO:0036156)
0.1	0.7	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	1.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	0.8	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	1.1	GO:0042588	zymogen granule(GO:0042588)
0.1	1.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.3	GO:0002142	stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.1	0.7	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1	0.7	GO:0030891	VCB complex(GO:0030891)
0.1	0.3	GO:0098890	extrinsic component of postsynaptic membrane(GO:0098890)
0.0	0.6	GO:0032433	filopodium tip(GO:0032433)
0.0	0.9	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	1.5	GO:0005614	interstitial matrix(GO:0005614)
0.0	1.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.7	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.8	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.7	GO:0043083	synaptic cleft(GO:0043083)
0.0	2.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	0.7	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0005715	late recombination nodule(GO:0005715)
0.0	0.1	GO:0002095	caveolar macromolecular signaling complex(GO:0002095)
0.0	77.0	GO:0005783	endoplasmic reticulum(GO:0005783)
0.0	0.7	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.3	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.7	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.3	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	1.2	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.3	GO:0098839	postsynaptic density membrane(GO:0098839)
0.0	0.6	GO:0032590	dendrite membrane(GO:0032590)
0.0	3.7	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.9	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.9	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.6	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	0.6	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.3	GO:0071203	WASH complex(GO:0071203)
0.0	1.0	GO:0016235	aggresome(GO:0016235)
0.0	2.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.6	GO:0010369	chromocenter(GO:0010369)
0.0	3.3	GO:0000795	synaptonemal complex(GO:0000795)
0.0	1.1	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.5	GO:0016580	Sin3 complex(GO:0016580)
0.0	1.3	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	1.9	GO:0055037	recycling endosome(GO:0055037)
0.0	0.6	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.5	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	2.0	GO:0030175	filopodium(GO:0030175)
0.0	2.3	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	1.3	GO:0031526	brush border membrane(GO:0031526)
0.0	0.6	GO:0001533	cornified envelope(GO:0001533)
0.0	1.9	GO:0031514	motile cilium(GO:0031514)
0.0	0.7	GO:0032421	stereocilium bundle(GO:0032421)
0.0	0.1	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	1.0	GO:0030139	endocytic vesicle(GO:0030139)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.5	18.1	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
2.2	13.4	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
2.2	13.0	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
1.8	5.3	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.7	10.4	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.7	5.2	GO:0046911	metal chelating activity(GO:0046911)
1.4	4.1	GO:0004658	propionyl-CoA carboxylase activity(GO:0004658)
1.3	5.3	GO:1902271	D3 vitamins binding(GO:1902271)
1.3	6.4	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.2	27.2	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
1.0	6.0	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.0	4.8	GO:0051185	coenzyme transporter activity(GO:0051185)
0.9	4.6	GO:0004031	aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdenum ion binding(GO:0030151)
0.9	6.3	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.9	3.5	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.8	2.5	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.8	3.4	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.8	2.3	GO:0017099	very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.8	5.4	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.7	4.4	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.7	2.1	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.7	2.0	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372)
0.6	2.4	GO:0019862	IgA binding(GO:0019862)
0.6	13.2	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
0.6	4.5	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.5	3.3	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.5	2.0	GO:0008802	betaine-aldehyde dehydrogenase activity(GO:0008802)
0.5	12.6	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.5	2.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.5	1.9	GO:0003844	1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.5	1.9	GO:0046997	oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.5	1.4	GO:0080023	3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.5	2.7	GO:0008142	oxysterol binding(GO:0008142)
0.4	3.0	GO:0004556	alpha-amylase activity(GO:0004556)
0.4	9.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.4	5.4	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.4	1.2	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.4	2.7	GO:0042328	heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.4	2.6	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.4	2.3	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.3	3.8	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3	5.5	GO:0005243	gap junction channel activity(GO:0005243)
0.3	4.4	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.3	1.3	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.3	3.3	GO:1901612	cardiolipin binding(GO:1901612)
0.3	8.1	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.3	10.0	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3	1.6	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.3	1.9	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.3	1.2	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.3	6.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.3	0.9	GO:0005110	frizzled-2 binding(GO:0005110)
0.3	0.8	GO:0047598	sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598)
0.3	0.6	GO:1902379	chemoattractant activity involved in axon guidance(GO:1902379)
0.3	0.8	GO:0030350	iron-responsive element binding(GO:0030350)
0.3	0.8	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.3	10.7	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.3	0.8	GO:0004368	glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.3	1.0	GO:0004103	choline kinase activity(GO:0004103)
0.3	6.8	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.3	2.8	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2	4.2	GO:0070403	NAD+ binding(GO:0070403)
0.2	2.2	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.2	0.7	GO:1901375	acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.2	5.9	GO:0001848	complement binding(GO:0001848)
0.2	1.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.2	0.2	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2	2.4	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.2	3.3	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.2	1.6	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.2	0.8	GO:0033883	pyridoxal phosphatase activity(GO:0033883)
0.2	5.7	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2	2.9	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.2	0.6	GO:0031531	thyrotropin-releasing hormone receptor binding(GO:0031531)
0.2	3.6	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2	0.4	GO:0001847	opsonin receptor activity(GO:0001847)
0.2	0.9	GO:0097001	ceramide binding(GO:0097001)
0.2	2.9	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.2	0.7	GO:0005008	hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2	0.7	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.2	0.9	GO:1904288	BAT3 complex binding(GO:1904288)
0.2	1.0	GO:0008453	alanine-glyoxylate transaminase activity(GO:0008453)
0.2	0.5	GO:0004510	tryptophan 5-monooxygenase activity(GO:0004510)
0.2	2.3	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.2	3.0	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.1	0.4	GO:0097604	temperature-gated cation channel activity(GO:0097604)
0.1	0.5	GO:0019809	spermidine binding(GO:0019809)
0.1	1.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1	1.4	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	4.9	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1	0.4	GO:0004771	sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
0.1	2.2	GO:0017127	cholesterol transporter activity(GO:0017127)
0.1	2.5	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.1	1.4	GO:0030983	mismatched DNA binding(GO:0030983)
0.1	1.1	GO:0031419	cobalamin binding(GO:0031419)
0.1	2.8	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.1	0.8	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	0.6	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	0.5	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.7	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.6	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	2.3	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1	0.6	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	11.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.7	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	4.0	GO:0001786	phosphatidylserine binding(GO:0001786)
0.1	0.3	GO:0030156	benzodiazepine receptor binding(GO:0030156)
0.1	0.4	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.1	1.8	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.1	0.9	GO:0043121	neurotrophin binding(GO:0043121) nerve growth factor binding(GO:0048406)
0.1	2.6	GO:0042605	peptide antigen binding(GO:0042605)
0.1	1.2	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.1	0.9	GO:0019957	C-C chemokine binding(GO:0019957)
0.1	0.6	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1	0.3	GO:0038100	nodal binding(GO:0038100) activin receptor binding(GO:0070697)
0.1	0.7	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.5	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.1	0.7	GO:0070097	delta-catenin binding(GO:0070097)
0.1	1.2	GO:0035497	cAMP response element binding(GO:0035497)
0.1	0.6	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	1.2	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	1.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.1	0.7	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	0.3	GO:0008384	IkappaB kinase activity(GO:0008384)
0.1	0.6	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.5	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	0.5	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.1	4.4	GO:0038024	cargo receptor activity(GO:0038024)
0.1	2.0	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.1	1.1	GO:0001972	retinoic acid binding(GO:0001972)
0.1	0.5	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	3.4	GO:0016836	hydro-lyase activity(GO:0016836)
0.0	0.2	GO:0004452	isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.0	0.2	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0	1.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.2	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.0	0.9	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.7	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.7	GO:0001164	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.9	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.3	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	2.0	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.0	0.6	GO:0015926	glucosidase activity(GO:0015926)
0.0	2.2	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.9	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.4	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	2.4	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.4	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0	0.9	GO:0031489	myosin V binding(GO:0031489)
0.0	0.3	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	2.1	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0	0.2	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.0	2.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	2.4	GO:0051082	unfolded protein binding(GO:0051082)
0.0	5.1	GO:0052689	carboxylic ester hydrolase activity(GO:0052689)
0.0	0.1	GO:0005136	interleukin-4 receptor binding(GO:0005136)
0.0	1.4	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	1.0	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	1.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	1.0	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	1.1	GO:0016876	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	3.1	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0	0.5	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.3	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.3	GO:0019956	chemokine binding(GO:0019956)
0.0	0.3	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0001595	angiotensin receptor activity(GO:0001595)
0.0	0.1	GO:0001607	neuromedin U receptor activity(GO:0001607)
0.0	0.1	GO:0015154	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.2	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	2.4	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	2.0	GO:0016503	pheromone receptor activity(GO:0016503)
0.0	1.1	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.5	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	1.7	GO:0008170	N-methyltransferase activity(GO:0008170)
0.0	0.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.5	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.2	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.8	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.6	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.2	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	1.2	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0	0.1	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.3	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	1.6	GO:0008083	growth factor activity(GO:0008083)
0.0	0.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.4	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.9	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.8	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2	4.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	5.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	4.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	4.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	2.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	1.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	5.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	17.8	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	2.7	PID ARF6 PATHWAY	Arf6 signaling events
0.1	3.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	2.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	3.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	3.1	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	1.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.7	PID ARF 3PATHWAY	Arf1 pathway
0.0	1.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.6	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.4	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.5	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.6	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	26.7	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.4	10.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.3	4.8	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.3	4.7	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.3	6.1	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.3	3.0	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	4.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2	6.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.2	4.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.2	4.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.2	4.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2	7.7	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.2	3.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.2	2.8	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.1	6.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	2.0	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	5.3	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.1	4.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	2.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1	1.6	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	3.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	0.8	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	2.5	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	2.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	2.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	4.8	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	0.8	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	2.9	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	0.9	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	1.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	2.3	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	3.3	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	1.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	3.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	3.1	REACTOME UNFOLDED PROTEIN RESPONSE	Genes involved in Unfolded Protein Response
0.0	4.0	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.3	REACTOME NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Neurotransmitter Release Cycle
0.0	0.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	2.1	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	1.3	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	5.2	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.9	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.5	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.4	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	2.0	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	1.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.7	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.8	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	1.5	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.6	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins

Results for Cux1

Z-value: 1.34

Motif logo

Transcription factors associated with Cux1

Activity-expression correlation:

Activity profile of Cux1 motif

Sorted Z-values of Cux1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Cux1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: