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GSE58827: Dynamics of the Mouse Liver

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Results for Ddit3

Z-value: 0.53

Motif logo

Transcription factors associated with Ddit3

Gene Symbol Gene ID Gene Info
ENSMUSG00000025408.16 DNA-damage inducible transcript 3
ENSMUSG00000116429.2 DNA-damage inducible transcript 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ddit3mm39_v1_chr10_+_127126643_127126698-0.382.1e-02Click!

Activity profile of Ddit3 motif

Sorted Z-values of Ddit3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_105858432 2.29 ENSMUST00000161289.2
carboxylesterase 4A
chr2_+_119181703 2.23 ENSMUST00000028780.4
ChaC, cation transport regulator 1
chr14_-_67106037 1.46 ENSMUST00000022629.9
dihydropyrimidinase-like 2
chr7_-_46365108 1.29 ENSMUST00000006956.9
ENSMUST00000210913.2
serum amyloid A 3
chr5_+_33879018 0.76 ENSMUST00000201437.4
ENSMUST00000067150.14
ENSMUST00000169212.9
ENSMUST00000114411.9
ENSMUST00000164207.10
ENSMUST00000087820.8
fibroblast growth factor receptor 3
chr11_-_95966407 0.75 ENSMUST00000107686.8
ENSMUST00000107684.2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
chr11_+_70104929 0.72 ENSMUST00000094055.10
ENSMUST00000126296.8
ENSMUST00000136328.2
ENSMUST00000153993.3
solute carrier family 16 (monocarboxylic acid transporters), member 11
chr6_+_21215472 0.68 ENSMUST00000081542.6
potassium voltage-gated channel, Shal-related family, member 2
chr6_+_45036970 0.67 ENSMUST00000114641.8
contactin associated protein-like 2
chr6_+_90443293 0.66 ENSMUST00000203607.2
Kruppel-like factor 15
chr6_+_38511758 0.65 ENSMUST00000019833.5
formation of mitochondrial complex V assembly factor 1
chr11_-_95966477 0.63 ENSMUST00000090541.12
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
chr18_+_39126178 0.62 ENSMUST00000097593.9
Rho GTPase activating protein 26
chr8_-_71085097 0.60 ENSMUST00000110103.2
growth differentiation factor 15
chr11_+_70104736 0.60 ENSMUST00000171032.8
solute carrier family 16 (monocarboxylic acid transporters), member 11
chr1_-_51955054 0.54 ENSMUST00000018561.14
ENSMUST00000114537.9
myosin IB
chr8_+_85807566 0.54 ENSMUST00000140621.2
WD repeat domain 83 opposite strand
chr1_-_51955126 0.53 ENSMUST00000046390.14
myosin IB
chr3_-_91990439 0.51 ENSMUST00000058150.8
loricrin
chr8_+_85807369 0.50 ENSMUST00000079764.14
WD repeat domain 83 opposite strand
chr11_+_95152355 0.50 ENSMUST00000021242.5
tachykinin 4
chr7_+_43362823 0.49 ENSMUST00000206554.2
kallikrein related-peptidase 13
chr9_+_20556088 0.49 ENSMUST00000162303.8
ENSMUST00000161486.8
ubiquitin-like 5
chr1_-_5089564 0.48 ENSMUST00000002533.15
regulator of G-protein signaling 20
chr18_+_37440497 0.47 ENSMUST00000056712.4
protocadherin beta 4
chr7_+_126376099 0.44 ENSMUST00000038614.12
ENSMUST00000170882.8
ENSMUST00000106359.2
ENSMUST00000106357.8
ENSMUST00000145762.8
yippee like 3
chr8_+_46080840 0.43 ENSMUST00000135336.9
sorbin and SH3 domain containing 2
chr7_+_126376353 0.43 ENSMUST00000106356.2
yippee like 3
chr9_+_20556147 0.43 ENSMUST00000161882.8
ubiquitin-like 5
chr18_-_35760260 0.42 ENSMUST00000025212.8
solute carrier family 23 (nucleobase transporters), member 1
chr5_-_44139121 0.42 ENSMUST00000199894.2
fibroblast growth factor binding protein 1
chr5_+_137551790 0.42 ENSMUST00000136565.8
ENSMUST00000149292.8
ENSMUST00000125489.2
actin-like 6B
chr11_-_103109247 0.41 ENSMUST00000103076.2
spermatogenesis associated 32
chr3_+_29568055 0.38 ENSMUST00000140288.2
EGF-like and EMI domain containing 1
chr2_-_90735171 0.38 ENSMUST00000005647.4
NADH:ubiquinone oxidoreductase core subunit S3
chr11_+_60619224 0.38 ENSMUST00000018743.5
mitochondrial elongation factor 2
chr7_+_126376319 0.38 ENSMUST00000132643.2
yippee like 3
chr5_-_44139099 0.37 ENSMUST00000061299.9
fibroblast growth factor binding protein 1
chr11_+_110289941 0.37 ENSMUST00000020949.12
ENSMUST00000100260.2
mitogen-activated protein kinase kinase 6
chr9_+_65278979 0.37 ENSMUST00000239433.2
ubiquitin-associated protein 1-like
chr7_+_30475819 0.37 ENSMUST00000041703.10
dermokine
chr8_+_12965876 0.37 ENSMUST00000110876.9
ENSMUST00000110879.9
mcf.2 transforming sequence-like
chr14_+_66208253 0.37 ENSMUST00000138191.8
clusterin
chr19_+_47853981 0.37 ENSMUST00000120645.8
glutathione S-transferase omega 2
chr17_-_25459086 0.36 ENSMUST00000038973.7
ENSMUST00000115154.11
N-acetylglucosamine-1-phosphotransferase, gamma subunit
chr5_+_137551774 0.36 ENSMUST00000136088.8
ENSMUST00000139395.8
actin-like 6B
chr11_+_110888313 0.35 ENSMUST00000106635.2
potassium inwardly-rectifying channel, subfamily J, member 16
chr14_+_53913598 0.35 ENSMUST00000103662.6
T cell receptor alpha variable 9-4
chr15_+_102922247 0.35 ENSMUST00000001709.3
homeobox C5
chr8_-_100143029 0.34 ENSMUST00000155527.8
ENSMUST00000142129.8
ENSMUST00000093249.11
ENSMUST00000142475.3
ENSMUST00000128860.8
cadherin 8
chr18_+_39126325 0.33 ENSMUST00000137497.9
Rho GTPase activating protein 26
chr17_-_15163362 0.33 ENSMUST00000238668.2
ENSMUST00000228330.2
WD repeat domain 27
chr19_+_47854012 0.32 ENSMUST00000237514.2
glutathione S-transferase omega 2
chr7_-_103845192 0.32 ENSMUST00000106859.3
olfactory receptor 649
chr5_+_32616566 0.32 ENSMUST00000202078.2
protein phosphatase 1 catalytic subunit beta
chr8_-_111808488 0.32 ENSMUST00000188466.7
C-type lectin domain family 18, member A
chr1_+_36753607 0.32 ENSMUST00000208994.2
RIKEN cDNA 4933424G06 gene
chr7_+_144450260 0.32 ENSMUST00000033389.7
ENSMUST00000207229.2
fibroblast growth factor 15
chr11_+_54194624 0.31 ENSMUST00000093106.12
acyl-CoA synthetase long-chain family member 6
chr10_-_95158827 0.31 ENSMUST00000220279.2
CASP2 and RIPK1 domain containing adaptor with death domain
chr14_+_66208498 0.30 ENSMUST00000128539.8
clusterin
chr7_+_99659121 0.30 ENSMUST00000107084.8
chordin-like 2
chr7_+_30681287 0.30 ENSMUST00000128384.3
family with sequence similarity 187, member B
chrX_+_165021919 0.30 ENSMUST00000060210.14
ENSMUST00000112233.8
glycoprotein m6b
chr2_-_121637469 0.30 ENSMUST00000110592.2
FERM domain containing 5
chr5_-_129916283 0.30 ENSMUST00000094280.4
coiled-coil-helix-coiled-coil-helix domain containing 2
chr19_+_47853954 0.29 ENSMUST00000235896.2
glutathione S-transferase omega 2
chr9_+_18848418 0.29 ENSMUST00000218385.2
olfactory receptor 832
chr15_-_12549963 0.29 ENSMUST00000189324.2
PDZ domain containing 2
chr9_-_45817666 0.29 ENSMUST00000161187.8
ring finger protein 214
chr5_-_53864595 0.29 ENSMUST00000200691.4
cholecystokinin A receptor
chr12_-_87149124 0.28 ENSMUST00000110176.2
neuroglobin
chr7_+_120682472 0.28 ENSMUST00000171880.3
ENSMUST00000047025.15
ENSMUST00000170106.2
ENSMUST00000168311.8
otoancorin
chr19_+_4889394 0.28 ENSMUST00000088653.3
coiled-coil domain containing 87
chrX_-_105528503 0.28 ENSMUST00000138724.8
ENSMUST00000149331.2
fibronectin type III domain containing 3C1
chr2_+_140012560 0.28 ENSMUST00000044825.5
NADH:ubiquinone oxidoreductase complex assembly factor 5
chr1_-_37469037 0.28 ENSMUST00000027286.7
cytochrome C oxidase assembly factor 5
chr2_+_109522781 0.27 ENSMUST00000111050.10
brain derived neurotrophic factor
chr19_+_8975249 0.27 ENSMUST00000236390.2
AHNAK nucleoprotein (desmoyokin)
chr9_+_57143839 0.27 ENSMUST00000093837.5
taste receptor cell gene 1
chr8_+_127025265 0.27 ENSMUST00000108759.3
solute carrier family 35, member F3
chr2_+_147203845 0.27 ENSMUST00000126068.9
paired box 1
chr2_-_153712996 0.26 ENSMUST00000028982.5
Sad1 and UNC84 domain containing 5
chr8_-_85807308 0.26 ENSMUST00000093357.12
WD repeat domain containing 83
chr10_-_95159410 0.25 ENSMUST00000217809.2
CASP2 and RIPK1 domain containing adaptor with death domain
chr7_+_102289455 0.25 ENSMUST00000098221.2
olfactory receptor 554
chr2_+_22959223 0.25 ENSMUST00000114523.10
acyl-Coenzyme A binding domain containing 5
chr3_+_108646974 0.25 ENSMUST00000133931.9
AKNA domain containing 1
chr4_-_56990306 0.25 ENSMUST00000053681.6
ferric-chelate reductase 1 like
chr4_+_154921916 0.25 ENSMUST00000207854.2
tetratricopeptide repeat domain 34
chr3_-_151541603 0.25 ENSMUST00000106126.2
prostaglandin F receptor
chr19_+_46750016 0.25 ENSMUST00000099373.12
ENSMUST00000077666.6
cyclin M2
chr2_+_90229027 0.24 ENSMUST00000216111.3
olfactory receptor 1274
chr6_+_18170686 0.24 ENSMUST00000045706.12
cystic fibrosis transmembrane conductance regulator
chr11_-_87716849 0.24 ENSMUST00000103177.10
lactoperoxidase
chr7_+_120276801 0.23 ENSMUST00000208454.2
ENSMUST00000060175.8
modulator of smoothened
chr17_+_26633794 0.23 ENSMUST00000182897.8
ENSMUST00000183077.8
ENSMUST00000053020.8
neuralized E3 ubiquitin protein ligase 1B
chr7_-_42376441 0.23 ENSMUST00000166837.2
predicted gene 17067
chr2_-_172296662 0.23 ENSMUST00000161334.2
glucosaminyl (N-acetyl) transferase family member 7
chr15_-_43733389 0.23 ENSMUST00000067469.6
transmembrane protein 74
chr4_-_117622747 0.23 ENSMUST00000062747.6
Kruppel-like factor 17
chrX_-_166638057 0.22 ENSMUST00000238211.2
FERM and PDZ domain containing 4
chr5_-_92511136 0.22 ENSMUST00000077820.6
chemokine (C-X-C motif) ligand 11
chr17_-_5468938 0.22 ENSMUST00000189788.2
lactate dehydrogenase A-like 6B
chr2_+_36263531 0.22 ENSMUST00000072114.4
ENSMUST00000217511.2
olfactory receptor 338
chr6_-_125143425 0.22 ENSMUST00000117757.9
ENSMUST00000073605.15
glyceraldehyde-3-phosphate dehydrogenase
chr3_-_153611775 0.22 ENSMUST00000005630.11
mutS homolog 4
chr7_-_23206631 0.22 ENSMUST00000227713.2
vomeronasal 1 receptor 167
chr3_-_58433313 0.22 ENSMUST00000029385.9
stress-associated endoplasmic reticulum protein 1
chr5_-_108922819 0.22 ENSMUST00000200159.2
ENSMUST00000212212.2
ring finger protein 212
chr4_+_112470794 0.22 ENSMUST00000058791.14
ENSMUST00000186969.2
selection and upkeep of intraepithelial T cells 2
chr2_-_91025208 0.22 ENSMUST00000111355.8
nuclear receptor subfamily 1, group H, member 3
chr4_-_101701220 0.22 ENSMUST00000106919.8
PRAME like 17
chr1_-_126420420 0.22 ENSMUST00000162877.8
NCK-associated protein 5
chr8_-_68270870 0.21 ENSMUST00000059374.5
pleckstrin and Sec7 domain containing 3
chrX_+_102465616 0.21 ENSMUST00000182089.2
predicted gene, 26992
chr13_+_34918820 0.21 ENSMUST00000039605.8
family with sequence similarity 50, member B
chr14_+_66208613 0.21 ENSMUST00000144619.2
clusterin
chr12_+_78738425 0.21 ENSMUST00000218697.2
ENSMUST00000219551.2
ENSMUST00000220396.2
family with sequence similarity 71, member D
chr6_-_125142539 0.20 ENSMUST00000183272.2
ENSMUST00000182052.8
ENSMUST00000182277.2
glyceraldehyde-3-phosphate dehydrogenase
chr6_+_17463748 0.20 ENSMUST00000115443.8
met proto-oncogene
chrX_-_59193003 0.20 ENSMUST00000033478.5
ENSMUST00000101531.10
mcf.2 transforming sequence
chr14_+_26789345 0.20 ENSMUST00000226105.2
interleukin 17 receptor D
chr9_-_121324705 0.20 ENSMUST00000216138.2
cholecystokinin
chr16_-_45544960 0.20 ENSMUST00000096057.5
transgelin 3
chr12_+_78738288 0.19 ENSMUST00000077968.5
family with sequence similarity 71, member D
chr11_-_6015736 0.19 ENSMUST00000002817.12
ENSMUST00000109813.9
ENSMUST00000090443.10
calcium/calmodulin-dependent protein kinase II, beta
chr18_+_37063237 0.19 ENSMUST00000193839.6
ENSMUST00000070797.7
protocadherin alpha 1
chr5_-_53864874 0.19 ENSMUST00000031093.5
cholecystokinin A receptor
chr14_+_53828314 0.19 ENSMUST00000103654.3
T cell receptor alpha variable 9-2
chr1_+_5658716 0.18 ENSMUST00000160777.8
ENSMUST00000239100.2
ENSMUST00000027038.11
opioid receptor, kappa 1
chr17_+_69382668 0.18 ENSMUST00000223610.2
erythrocyte membrane protein band 4.1 like 3
chr19_+_9824919 0.18 ENSMUST00000179814.3
secretoglobin, family 2A, member 2
chr4_+_129841340 0.18 ENSMUST00000128007.8
SPOC domain containing 1
chr7_-_125681577 0.18 ENSMUST00000073935.7
GSG1-like
chr2_-_91025441 0.18 ENSMUST00000002177.9
nuclear receptor subfamily 1, group H, member 3
chrX_-_74207359 0.18 ENSMUST00000101433.9
small integral membrane protein 9
chr17_-_15784582 0.18 ENSMUST00000147532.8
PR domain containing 9
chr2_-_90054837 0.18 ENSMUST00000213994.3
olfactory receptor 1506
chr14_-_51287620 0.17 ENSMUST00000076106.4
ribonuclease, RNase A family, 11 (non-active)
chr9_-_58009508 0.17 ENSMUST00000119665.2
coiled-coil domain containing 33
chr18_+_37554471 0.17 ENSMUST00000053073.6
protocadherin beta 11
chr3_-_152045986 0.17 ENSMUST00000199397.2
ENSMUST00000199334.5
ENSMUST00000068243.11
ENSMUST00000073089.13
mitoguardin 1
chr6_+_42377172 0.17 ENSMUST00000057398.4
taste receptor, type 2, member 143
chr9_-_121324744 0.17 ENSMUST00000035120.6
cholecystokinin
chr15_-_98674910 0.16 ENSMUST00000228594.2
ENSMUST00000226846.2
wingless-type MMTV integration site family, member 10B
chr7_+_84178162 0.16 ENSMUST00000180387.3
predicted gene 2115
chr6_+_116528102 0.16 ENSMUST00000122096.3
eukaryotic translation initiation factor 4A3 like 2
chr14_+_54183465 0.16 ENSMUST00000197130.5
ENSMUST00000103677.3
T cell receptor delta variable 2-1
chr1_-_161807205 0.16 ENSMUST00000162676.2
RIKEN cDNA 4930558K02 gene
chr6_+_120070307 0.16 ENSMUST00000112711.9
ninjurin 2
chr9_+_104446682 0.16 ENSMUST00000057742.15
copine IV
chr3_+_82287380 0.16 ENSMUST00000195793.2
microtubule-associated protein 9
chr5_-_131567526 0.16 ENSMUST00000161374.8
autism susceptibility candidate 2
chr4_+_101407608 0.15 ENSMUST00000094953.11
ENSMUST00000106933.2
DnaJ heat shock protein family (Hsp40) member C6
chr9_+_107957621 0.15 ENSMUST00000035211.14
macrophage stimulating 1 (hepatocyte growth factor-like)
chr2_+_121787131 0.15 ENSMUST00000110574.8
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr7_+_134870237 0.15 ENSMUST00000210697.2
ENSMUST00000097983.5
neuropeptide S
chr9_-_108305683 0.15 ENSMUST00000076592.4
interactor of HORMAD1 1
chr5_-_113229445 0.15 ENSMUST00000131708.2
ENSMUST00000117143.8
ENSMUST00000119627.8
crystallin, beta B3
chr7_-_104677667 0.15 ENSMUST00000215899.2
ENSMUST00000214318.3
olfactory receptor 675
chr19_-_5156995 0.15 ENSMUST00000237438.2
ENSMUST00000236149.2
ENSMUST00000025804.7
RAB1B, member RAS oncogene family
chr9_+_38312994 0.15 ENSMUST00000214648.3
ENSMUST00000056364.3
olfactory receptor 147
chr7_-_79443536 0.15 ENSMUST00000032760.6
mesoderm posterior 1
chr19_-_12209960 0.15 ENSMUST00000207710.3
olfactory receptor 1432
chr6_+_88701578 0.14 ENSMUST00000150180.4
ENSMUST00000163271.8
monoglyceride lipase
chr2_+_90152544 0.14 ENSMUST00000214797.3
olfactory receptor 1565
chr2_-_91025380 0.14 ENSMUST00000111356.8
nuclear receptor subfamily 1, group H, member 3
chr5_+_32616187 0.14 ENSMUST00000015100.15
protein phosphatase 1 catalytic subunit beta
chr2_+_152446244 0.14 ENSMUST00000058086.6
defensin beta 36
chrX_+_51880056 0.14 ENSMUST00000101588.2
coiled-coil domain containing 160
chr5_-_129856237 0.14 ENSMUST00000118268.9
phosphoserine phosphatase
chr2_+_131048998 0.14 ENSMUST00000153097.3
adaptor-related protein 5 complex, sigma 1 subunit
chr18_-_60724855 0.14 ENSMUST00000056533.9
myozenin 3
chr14_-_70890521 0.13 ENSMUST00000062629.5
nucleophosmin/nucleoplasmin 2
chr2_-_88837317 0.13 ENSMUST00000216271.3
ENSMUST00000214809.3
olfactory receptor 1215
chr1_+_187995096 0.13 ENSMUST00000060479.14
usherin
chr17_+_69382694 0.13 ENSMUST00000225062.2
erythrocyte membrane protein band 4.1 like 3
chr14_+_32972324 0.13 ENSMUST00000131086.3
Rho GTPase activating protein 22
chrY_-_35085749 0.13 ENSMUST00000180170.2
predicted gene, 20855
chr9_+_107957640 0.13 ENSMUST00000162886.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr7_+_23811739 0.13 ENSMUST00000120006.8
ENSMUST00000005413.4
zinc finger protein 112
chr6_+_88701810 0.13 ENSMUST00000089449.5
monoglyceride lipase
chr9_-_40015750 0.13 ENSMUST00000213858.2
olfactory receptor 984
chr6_+_71299758 0.12 ENSMUST00000065248.9
CD8 antigen, beta chain 1
chr6_+_41510925 0.12 ENSMUST00000103285.2
T cell receptor beta joining 1-2
chr12_+_53294940 0.12 ENSMUST00000223358.3
neuronal PAS domain protein 3
chr3_-_58729732 0.12 ENSMUST00000191233.4
MINDY lysine 48 deubiquitinase 4B, pseudogene
chr18_+_37466877 0.12 ENSMUST00000194655.2
ENSMUST00000061717.4
protocadherin beta 6
chr14_-_47805861 0.12 ENSMUST00000228784.2
ENSMUST00000042988.7
autophagy related 14
chr1_-_39616445 0.12 ENSMUST00000062525.11
ring finger protein 149
chr8_-_68270936 0.12 ENSMUST00000120071.8
pleckstrin and Sec7 domain containing 3
chr7_+_6392535 0.12 ENSMUST00000207465.2
ENSMUST00000208338.2
zinc finger protein 28
chr6_-_57821483 0.12 ENSMUST00000226191.2
vomeronasal 1 receptor 21
chr1_+_34160331 0.11 ENSMUST00000183006.5
dystonin
chr18_+_42408418 0.11 ENSMUST00000091920.6
ENSMUST00000046972.14
ENSMUST00000236240.2
RNA binding motif protein 27
chr4_+_151081538 0.11 ENSMUST00000030803.2
urotensin 2
chr2_-_91025492 0.11 ENSMUST00000111354.2
nuclear receptor subfamily 1, group H, member 3
chr16_+_4964849 0.11 ENSMUST00000165810.2
ENSMUST00000230616.2
SEC14-like lipid binding 5
chrY_+_79332266 0.11 ENSMUST00000178063.2
predicted gene, 20916

Network of associatons between targets according to the STRING database.

First level regulatory network of Ddit3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0021762 substantia nigra development(GO:0021762) alveolar secondary septum development(GO:0061144)
0.2 0.7 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 2.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.9 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.4 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.4 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 1.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.4 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.7 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 1.0 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.3 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.1 0.3 GO:0061193 taste bud development(GO:0061193)
0.1 0.5 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.2 GO:1902161 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) positive regulation of establishment of Sertoli cell barrier(GO:1904446) negative regulation of type B pancreatic cell development(GO:2000077)
0.1 0.8 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.4 GO:0035822 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.1 0.5 GO:0090274 reduction of food intake in response to dietary excess(GO:0002023) positive regulation of somatostatin secretion(GO:0090274)
0.1 0.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 0.2 GO:0060466 activation of meiosis involved in egg activation(GO:0060466)
0.1 0.3 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 1.9 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.3 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.2 GO:0046877 regulation of saliva secretion(GO:0046877)
0.1 0.3 GO:0015888 thiamine transport(GO:0015888)
0.1 0.3 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1 1.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:0061056 sclerotome development(GO:0061056)
0.0 0.3 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 1.4 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.7 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.3 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904)
0.0 0.1 GO:0033967 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.2 GO:0051885 positive regulation of anagen(GO:0051885)
0.0 0.3 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.0 0.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.6 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.4 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.0 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.1 GO:0002849 positive regulation of tolerance induction dependent upon immune response(GO:0002654) regulation of peripheral tolerance induction(GO:0002658) positive regulation of peripheral tolerance induction(GO:0002660) regulation of peripheral T cell tolerance induction(GO:0002849) positive regulation of peripheral T cell tolerance induction(GO:0002851)
0.0 0.2 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0043056 forward locomotion(GO:0043056)
0.0 0.4 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.7 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.6 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.6 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.1 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.5 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.3 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.0 GO:0035874 amiloride transport(GO:0015898) cellular response to copper ion starvation(GO:0035874) response to azide(GO:0097184) cellular response to azide(GO:0097185)
0.0 0.0 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.1 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.9 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0097632 extrinsic component of pre-autophagosomal structure membrane(GO:0097632)
0.0 0.2 GO:0005713 recombination nodule(GO:0005713)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.5 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 1.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.4 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 1.0 GO:0050610 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1 0.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.7 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.4 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.3 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 1.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.9 GO:0031386 protein tag(GO:0031386)
0.1 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.1 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.9 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.6 GO:0070513 death domain binding(GO:0070513)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 1.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0052597 diamine oxidase activity(GO:0052597) histamine oxidase activity(GO:0052598) methylputrescine oxidase activity(GO:0052599) propane-1,3-diamine oxidase activity(GO:0052600)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.9 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization