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GSE58827: Dynamics of the Mouse Liver
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Results for E2f1
Z-value: 5.77
Motif logo
Transcription factors associated with E2f1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
E2f1
|
ENSMUSG00000027490.18 | E2F transcription factor 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| E2f1 | mm39_v1_chr2_-_154411765_154411812 | 0.96 | 3.5e-20 | Click! |
Activity profile of E2f1 motif
Sorted Z-values of E2f1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of E2f1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 22.5 | 67.5 | GO:0003331 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
| 14.3 | 171.5 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 10.6 | 53.0 | GO:0072138 | mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) |
| 10.2 | 41.0 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 9.8 | 48.9 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
| 8.8 | 26.3 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
| 7.9 | 31.6 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 7.5 | 67.6 | GO:0046208 | spermine catabolic process(GO:0046208) |
| 7.1 | 28.3 | GO:1904009 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009) |
| 6.7 | 40.3 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 6.6 | 33.2 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 6.4 | 148.1 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 6.4 | 38.5 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
| 6.4 | 19.1 | GO:0018160 | peptidyl-pyrromethane cofactor linkage(GO:0018160) |
| 6.2 | 18.5 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
| 6.0 | 18.0 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
| 6.0 | 18.0 | GO:1900158 | negative regulation of bone mineralization involved in bone maturation(GO:1900158) |
| 5.8 | 40.7 | GO:0051572 | negative regulation of histone H3-K4 methylation(GO:0051572) |
| 5.8 | 52.0 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 5.6 | 16.9 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 5.6 | 22.5 | GO:0015904 | tetracycline transport(GO:0015904) |
| 5.4 | 21.7 | GO:1903943 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 5.4 | 16.1 | GO:0044413 | evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) |
| 5.4 | 59.1 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 5.3 | 16.0 | GO:0045004 | DNA replication proofreading(GO:0045004) |
| 5.3 | 21.3 | GO:0090096 | lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096) |
| 5.3 | 42.6 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
| 4.9 | 44.5 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 4.9 | 19.7 | GO:0000915 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 4.9 | 146.4 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 4.8 | 38.6 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
| 4.7 | 19.0 | GO:0060265 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) |
| 4.7 | 14.2 | GO:0098884 | postsynaptic neurotransmitter receptor internalization(GO:0098884) |
| 4.6 | 74.2 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
| 4.6 | 78.3 | GO:0033280 | response to vitamin D(GO:0033280) |
| 4.6 | 18.2 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 4.5 | 13.5 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) |
| 4.4 | 22.2 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 4.4 | 22.1 | GO:1904970 | brush border assembly(GO:1904970) |
| 4.4 | 8.8 | GO:0072356 | chromosome passenger complex localization to kinetochore(GO:0072356) |
| 4.3 | 21.7 | GO:1904975 | response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976) |
| 4.3 | 17.3 | GO:0072355 | histone H3-T3 phosphorylation(GO:0072355) |
| 4.2 | 29.4 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 4.1 | 20.4 | GO:0031509 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
| 4.1 | 20.3 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
| 4.0 | 24.0 | GO:0042117 | monocyte activation(GO:0042117) |
| 3.9 | 3.9 | GO:1905066 | regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) |
| 3.8 | 15.4 | GO:2001148 | dipeptide transmembrane transport(GO:0035442) regulation of oligopeptide transport(GO:0090088) regulation of dipeptide transport(GO:0090089) positive regulation of oligopeptide transport(GO:2000878) positive regulation of dipeptide transport(GO:2000880) regulation of dipeptide transmembrane transport(GO:2001148) positive regulation of dipeptide transmembrane transport(GO:2001150) |
| 3.7 | 11.0 | GO:1990428 | miRNA transport(GO:1990428) |
| 3.6 | 32.8 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 3.6 | 46.9 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 3.6 | 14.4 | GO:1904800 | regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) |
| 3.5 | 14.2 | GO:0055048 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 3.5 | 3.5 | GO:0072401 | signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) |
| 3.5 | 21.1 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 3.5 | 28.1 | GO:0042167 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 3.5 | 7.0 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 3.3 | 20.1 | GO:0045950 | negative regulation of mitotic recombination(GO:0045950) |
| 3.3 | 13.3 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 3.3 | 6.6 | GO:0072708 | response to sorbitol(GO:0072708) |
| 3.2 | 16.0 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 3.1 | 9.3 | GO:0045660 | positive regulation of neutrophil differentiation(GO:0045660) |
| 3.1 | 31.0 | GO:0007000 | nucleolus organization(GO:0007000) |
| 3.1 | 58.8 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 3.0 | 27.4 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 3.0 | 21.3 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 3.0 | 9.0 | GO:0042822 | pyridoxal phosphate metabolic process(GO:0042822) |
| 3.0 | 17.9 | GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) |
| 3.0 | 5.9 | GO:0031938 | regulation of chromatin silencing at telomere(GO:0031938) |
| 2.9 | 14.7 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 2.9 | 11.5 | GO:0009257 | 10-formyltetrahydrofolate biosynthetic process(GO:0009257) |
| 2.8 | 45.0 | GO:0019985 | translesion synthesis(GO:0019985) |
| 2.8 | 5.5 | GO:0015675 | nickel cation transport(GO:0015675) |
| 2.8 | 8.3 | GO:0010767 | regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) |
| 2.8 | 88.1 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
| 2.7 | 21.7 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
| 2.7 | 13.4 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 2.7 | 48.1 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 2.7 | 16.0 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 2.7 | 16.0 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 2.6 | 7.9 | GO:0009955 | adaxial/abaxial pattern specification(GO:0009955) regulation of adaxial/abaxial pattern formation(GO:2000011) |
| 2.6 | 7.8 | GO:2000422 | regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424) |
| 2.5 | 7.6 | GO:0071874 | cellular response to norepinephrine stimulus(GO:0071874) |
| 2.5 | 10.1 | GO:0098795 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
| 2.5 | 7.5 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 2.5 | 40.1 | GO:0046599 | regulation of centriole replication(GO:0046599) |
| 2.5 | 7.4 | GO:0072757 | cellular response to camptothecin(GO:0072757) |
| 2.4 | 7.2 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) |
| 2.4 | 12.0 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 2.4 | 4.7 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 2.3 | 18.5 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 2.2 | 8.8 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 2.1 | 2.1 | GO:0000019 | regulation of mitotic recombination(GO:0000019) |
| 2.1 | 46.0 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 2.1 | 8.3 | GO:0070650 | actin filament bundle distribution(GO:0070650) |
| 2.1 | 6.2 | GO:2000813 | negative regulation of barbed-end actin filament capping(GO:2000813) |
| 2.0 | 8.1 | GO:0051316 | attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316) |
| 2.0 | 12.1 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 1.9 | 5.8 | GO:0032240 | negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832) |
| 1.9 | 11.6 | GO:0006116 | NADH oxidation(GO:0006116) |
| 1.9 | 34.5 | GO:0030261 | chromosome condensation(GO:0030261) |
| 1.9 | 81.5 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
| 1.9 | 5.6 | GO:0032066 | nucleolus to nucleoplasm transport(GO:0032066) |
| 1.9 | 5.6 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
| 1.8 | 9.2 | GO:0048539 | bone marrow development(GO:0048539) |
| 1.8 | 7.2 | GO:1904046 | negative regulation of vascular endothelial growth factor production(GO:1904046) |
| 1.8 | 10.7 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 1.8 | 12.5 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 1.8 | 21.3 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 1.8 | 7.1 | GO:1901003 | negative regulation of fermentation(GO:1901003) |
| 1.8 | 5.3 | GO:1903281 | positive regulation of calcium:sodium antiporter activity(GO:1903281) |
| 1.8 | 17.7 | GO:0045719 | negative regulation of glycogen biosynthetic process(GO:0045719) |
| 1.8 | 7.0 | GO:2000409 | positive regulation of T cell extravasation(GO:2000409) |
| 1.7 | 1.7 | GO:0060057 | apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) |
| 1.7 | 12.1 | GO:0032055 | negative regulation of translation in response to stress(GO:0032055) negative regulation of interleukin-1 beta secretion(GO:0050713) |
| 1.7 | 6.9 | GO:0060447 | bud outgrowth involved in lung branching(GO:0060447) |
| 1.7 | 15.1 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 1.7 | 5.0 | GO:0032907 | transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 1.7 | 15.0 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 1.7 | 3.3 | GO:1901970 | positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101) |
| 1.6 | 6.6 | GO:0035524 | proline transmembrane transport(GO:0035524) |
| 1.6 | 3.3 | GO:0090004 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004) |
| 1.6 | 4.9 | GO:1901874 | regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874) |
| 1.6 | 19.7 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 1.6 | 3.2 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 1.6 | 33.4 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 1.6 | 9.4 | GO:0002326 | B cell lineage commitment(GO:0002326) |
| 1.6 | 50.3 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 1.6 | 9.4 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 1.6 | 4.7 | GO:0014057 | positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) |
| 1.6 | 10.9 | GO:0035625 | receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
| 1.6 | 9.4 | GO:0060160 | negative regulation of dopamine receptor signaling pathway(GO:0060160) |
| 1.6 | 14.0 | GO:0031125 | rRNA 3'-end processing(GO:0031125) |
| 1.5 | 7.7 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 1.5 | 12.4 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 1.5 | 4.6 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 1.5 | 3.0 | GO:1990918 | double-strand break repair involved in meiotic recombination(GO:1990918) |
| 1.5 | 16.5 | GO:0033260 | nuclear DNA replication(GO:0033260) |
| 1.5 | 6.0 | GO:1902263 | apoptotic process involved in embryonic digit morphogenesis(GO:1902263) |
| 1.5 | 6.0 | GO:0001777 | T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013) |
| 1.5 | 4.4 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 1.4 | 28.5 | GO:0051383 | kinetochore organization(GO:0051383) |
| 1.4 | 31.1 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 1.4 | 7.0 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 1.4 | 8.3 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 1.4 | 4.2 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 1.4 | 4.1 | GO:0007228 | positive regulation of hh target transcription factor activity(GO:0007228) |
| 1.4 | 4.1 | GO:0009107 | lipoate biosynthetic process(GO:0009107) |
| 1.4 | 5.4 | GO:0003017 | lymph circulation(GO:0003017) |
| 1.3 | 10.8 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 1.3 | 2.7 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
| 1.3 | 34.9 | GO:0045830 | positive regulation of isotype switching(GO:0045830) |
| 1.3 | 9.3 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 1.3 | 9.2 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 1.3 | 9.1 | GO:0010693 | negative regulation of alkaline phosphatase activity(GO:0010693) |
| 1.3 | 10.3 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 1.3 | 14.1 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 1.3 | 23.0 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 1.3 | 2.5 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
| 1.3 | 3.8 | GO:0042938 | dipeptide transport(GO:0042938) |
| 1.3 | 3.8 | GO:1903288 | positive regulation of potassium ion import(GO:1903288) |
| 1.3 | 16.3 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 1.2 | 12.5 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 1.2 | 29.5 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 1.2 | 8.5 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 1.2 | 3.6 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
| 1.2 | 6.0 | GO:0072734 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 1.2 | 8.4 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
| 1.2 | 22.8 | GO:0045005 | DNA-dependent DNA replication maintenance of fidelity(GO:0045005) |
| 1.2 | 4.7 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
| 1.2 | 12.9 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 1.2 | 3.5 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
| 1.2 | 10.4 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 1.1 | 18.3 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 1.1 | 6.9 | GO:0060398 | regulation of growth hormone receptor signaling pathway(GO:0060398) |
| 1.1 | 9.1 | GO:1903208 | neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208) |
| 1.1 | 5.6 | GO:0010825 | positive regulation of centrosome duplication(GO:0010825) |
| 1.1 | 4.5 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 1.1 | 12.1 | GO:0009086 | methionine biosynthetic process(GO:0009086) |
| 1.1 | 6.6 | GO:0019042 | viral latency(GO:0019042) |
| 1.1 | 6.4 | GO:0034508 | centromere complex assembly(GO:0034508) |
| 1.0 | 33.5 | GO:0044381 | glucose import in response to insulin stimulus(GO:0044381) |
| 1.0 | 94.9 | GO:0051225 | spindle assembly(GO:0051225) |
| 1.0 | 12.4 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 1.0 | 13.3 | GO:0072431 | signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) |
| 1.0 | 10.0 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 1.0 | 3.0 | GO:0097021 | lymphocyte migration into lymphoid organs(GO:0097021) |
| 1.0 | 9.9 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 1.0 | 8.8 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 1.0 | 13.6 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.9 | 3.8 | GO:0014010 | Schwann cell proliferation(GO:0014010) |
| 0.9 | 2.8 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
| 0.9 | 18.9 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.9 | 27.0 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.9 | 3.6 | GO:1900756 | protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923) |
| 0.8 | 5.1 | GO:1902963 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.8 | 3.3 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 0.8 | 1.7 | GO:0060435 | bronchiole development(GO:0060435) |
| 0.8 | 2.5 | GO:0045626 | interleukin-4-mediated signaling pathway(GO:0035771) negative regulation of T-helper 1 cell differentiation(GO:0045626) positive regulation of dendritic cell apoptotic process(GO:2000670) |
| 0.8 | 3.2 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
| 0.8 | 1.6 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 0.8 | 5.4 | GO:0035385 | Roundabout signaling pathway(GO:0035385) |
| 0.8 | 1.5 | GO:2000328 | regulation of T-helper 17 cell lineage commitment(GO:2000328) |
| 0.8 | 1.5 | GO:0002842 | positive regulation of T cell mediated immune response to tumor cell(GO:0002842) |
| 0.7 | 2.2 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.7 | 9.7 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.7 | 2.9 | GO:0071651 | positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651) |
| 0.7 | 6.6 | GO:0070535 | histone H2A K63-linked ubiquitination(GO:0070535) |
| 0.7 | 1.5 | GO:1905216 | positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216) |
| 0.7 | 7.2 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.7 | 1.4 | GO:0034970 | histone H3-R2 methylation(GO:0034970) histone H3-R17 methylation(GO:0034971) |
| 0.7 | 3.6 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
| 0.7 | 7.1 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.7 | 5.0 | GO:0010288 | response to lead ion(GO:0010288) |
| 0.7 | 2.8 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 0.7 | 3.5 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
| 0.7 | 6.9 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
| 0.7 | 2.8 | GO:0003360 | brainstem development(GO:0003360) |
| 0.7 | 22.0 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.7 | 19.9 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.7 | 5.3 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.7 | 10.7 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.7 | 3.3 | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
| 0.7 | 12.4 | GO:0048368 | lateral mesoderm development(GO:0048368) |
| 0.7 | 5.9 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.6 | 4.5 | GO:0010626 | negative regulation of Schwann cell proliferation(GO:0010626) |
| 0.6 | 7.7 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.6 | 8.3 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.6 | 20.8 | GO:0051310 | metaphase plate congression(GO:0051310) |
| 0.6 | 4.4 | GO:0032202 | telomere assembly(GO:0032202) |
| 0.6 | 0.6 | GO:0061141 | lung ciliated cell differentiation(GO:0061141) |
| 0.6 | 2.5 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
| 0.6 | 4.3 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.6 | 1.8 | GO:0007494 | midgut development(GO:0007494) |
| 0.6 | 0.6 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 0.6 | 10.9 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.6 | 5.4 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 0.6 | 3.6 | GO:0035022 | positive regulation of Rac protein signal transduction(GO:0035022) |
| 0.6 | 3.6 | GO:0018202 | peptidyl-histidine modification(GO:0018202) |
| 0.6 | 6.0 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
| 0.6 | 6.0 | GO:0035878 | nail development(GO:0035878) |
| 0.6 | 22.6 | GO:0006378 | mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631) |
| 0.6 | 1.8 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.6 | 5.3 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.6 | 2.9 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 0.6 | 11.2 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.6 | 7.0 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.6 | 2.9 | GO:0070668 | mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668) |
| 0.6 | 2.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.6 | 2.2 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.6 | 15.7 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.5 | 14.7 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.5 | 1.6 | GO:0036016 | response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) |
| 0.5 | 1.1 | GO:1903679 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 0.5 | 2.6 | GO:1905169 | protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171) |
| 0.5 | 1.6 | GO:0042275 | error-free postreplication DNA repair(GO:0042275) |
| 0.5 | 2.6 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
| 0.5 | 4.1 | GO:0032392 | DNA geometric change(GO:0032392) |
| 0.5 | 8.2 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.5 | 2.0 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.5 | 12.1 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.5 | 2.0 | GO:0021960 | anterior commissure morphogenesis(GO:0021960) |
| 0.5 | 7.6 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
| 0.5 | 5.5 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.5 | 4.5 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.5 | 11.9 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.5 | 7.4 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
| 0.5 | 1.5 | GO:0046061 | dATP catabolic process(GO:0046061) |
| 0.5 | 4.4 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.5 | 5.4 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.5 | 7.3 | GO:0000070 | mitotic sister chromatid segregation(GO:0000070) |
| 0.5 | 1.5 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 0.5 | 1.4 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
| 0.5 | 3.8 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.5 | 8.0 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
| 0.5 | 0.5 | GO:0072368 | regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368) |
| 0.5 | 0.9 | GO:0071288 | cellular response to mercury ion(GO:0071288) |
| 0.5 | 2.8 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
| 0.5 | 0.9 | GO:1901674 | histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) |
| 0.5 | 3.7 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.5 | 11.4 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.5 | 46.0 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.4 | 6.7 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
| 0.4 | 5.7 | GO:0071850 | mitotic cell cycle arrest(GO:0071850) |
| 0.4 | 0.4 | GO:0002840 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) |
| 0.4 | 3.3 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 0.4 | 7.1 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 0.4 | 3.7 | GO:1902510 | regulation of apoptotic DNA fragmentation(GO:1902510) |
| 0.4 | 8.3 | GO:0061615 | glycolytic process through fructose-6-phosphate(GO:0061615) |
| 0.4 | 14.0 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.4 | 3.3 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
| 0.4 | 5.6 | GO:0061072 | iris morphogenesis(GO:0061072) |
| 0.4 | 6.0 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.4 | 1.5 | GO:0061152 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 0.4 | 0.4 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
| 0.4 | 4.2 | GO:0071684 | blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
| 0.4 | 11.7 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.4 | 3.0 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 0.4 | 16.7 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.4 | 4.1 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.4 | 1.5 | GO:1902477 | defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477) |
| 0.4 | 4.4 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 0.4 | 3.2 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 0.4 | 1.4 | GO:2000656 | regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657) |
| 0.4 | 6.5 | GO:0060510 | Type II pneumocyte differentiation(GO:0060510) |
| 0.4 | 2.9 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.4 | 6.8 | GO:0036093 | germ cell proliferation(GO:0036093) |
| 0.4 | 0.7 | GO:0003220 | left ventricular cardiac muscle tissue morphogenesis(GO:0003220) |
| 0.3 | 17.8 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.3 | 6.3 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.3 | 8.3 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.3 | 14.1 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
| 0.3 | 1.7 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 0.3 | 3.2 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.3 | 15.8 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.3 | 1.6 | GO:0003349 | epicardium-derived cardiac endothelial cell differentiation(GO:0003349) cardiac vascular smooth muscle cell development(GO:0060948) |
| 0.3 | 5.7 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.3 | 5.0 | GO:0071158 | positive regulation of cell cycle arrest(GO:0071158) |
| 0.3 | 6.8 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.3 | 2.1 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.3 | 4.6 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.3 | 12.3 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 0.3 | 6.6 | GO:0006907 | pinocytosis(GO:0006907) |
| 0.3 | 7.6 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.3 | 1.1 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.3 | 10.3 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 0.3 | 27.6 | GO:0000910 | cytokinesis(GO:0000910) |
| 0.3 | 52.8 | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.3 | 1.1 | GO:0003256 | regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256) |
| 0.3 | 0.8 | GO:1902525 | regulation of protein monoubiquitination(GO:1902525) |
| 0.3 | 4.4 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
| 0.3 | 1.6 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.3 | 4.9 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
| 0.3 | 1.6 | GO:0034351 | negative regulation of glial cell apoptotic process(GO:0034351) |
| 0.3 | 4.0 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.3 | 2.1 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.3 | 5.7 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.3 | 1.3 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 0.2 | 1.7 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
| 0.2 | 18.5 | GO:0006661 | phosphatidylinositol biosynthetic process(GO:0006661) |
| 0.2 | 1.0 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.2 | 1.5 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.2 | 1.7 | GO:0048496 | maintenance of organ identity(GO:0048496) |
| 0.2 | 2.4 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.2 | 1.7 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.2 | 1.4 | GO:0034465 | response to carbon monoxide(GO:0034465) eye blink reflex(GO:0060082) |
| 0.2 | 6.8 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.2 | 7.6 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
| 0.2 | 1.4 | GO:0045583 | regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585) |
| 0.2 | 2.0 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.2 | 1.5 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.2 | 0.6 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
| 0.2 | 1.9 | GO:0007289 | spermatid nucleus differentiation(GO:0007289) |
| 0.2 | 1.0 | GO:0060767 | epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) |
| 0.2 | 16.9 | GO:0032755 | positive regulation of interleukin-6 production(GO:0032755) |
| 0.2 | 0.8 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.2 | 3.6 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
| 0.2 | 2.0 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.2 | 0.8 | GO:0070350 | RNA repair(GO:0042245) white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) |
| 0.2 | 0.8 | GO:0009146 | purine nucleoside triphosphate catabolic process(GO:0009146) |
| 0.2 | 1.2 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.2 | 4.1 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.2 | 3.1 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.2 | 0.4 | GO:0043697 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) |
| 0.2 | 3.4 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.2 | 4.6 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.2 | 0.8 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.2 | 0.9 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.2 | 0.2 | GO:1901994 | negative regulation of meiotic cell cycle phase transition(GO:1901994) |
| 0.2 | 8.9 | GO:0009409 | response to cold(GO:0009409) |
| 0.2 | 1.2 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.2 | 1.2 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.2 | 0.5 | GO:0060671 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 0.2 | 1.5 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.2 | 4.3 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.2 | 3.3 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 0.2 | 2.3 | GO:0070203 | regulation of establishment of protein localization to telomere(GO:0070203) protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173) |
| 0.2 | 2.6 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.2 | 0.2 | GO:0072610 | interleukin-12 secretion(GO:0072610) regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184) |
| 0.2 | 0.9 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.2 | 5.1 | GO:0033045 | regulation of sister chromatid segregation(GO:0033045) |
| 0.1 | 1.9 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.1 | 1.5 | GO:0035608 | protein deglutamylation(GO:0035608) |
| 0.1 | 6.8 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.1 | 3.9 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.1 | 2.6 | GO:0032695 | negative regulation of interleukin-12 production(GO:0032695) |
| 0.1 | 7.1 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.1 | 2.1 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.1 | 0.5 | GO:2000973 | regulation of pro-B cell differentiation(GO:2000973) |
| 0.1 | 2.5 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.1 | 5.5 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.1 | 1.2 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.1 | 1.2 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.1 | 3.2 | GO:0021535 | cell migration in hindbrain(GO:0021535) |
| 0.1 | 1.9 | GO:0006356 | regulation of transcription from RNA polymerase I promoter(GO:0006356) |
| 0.1 | 2.1 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
| 0.1 | 0.2 | GO:0061209 | cell proliferation involved in mesonephros development(GO:0061209) |
| 0.1 | 1.4 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.1 | 2.5 | GO:0070193 | synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193) |
| 0.1 | 8.0 | GO:0001954 | positive regulation of cell-matrix adhesion(GO:0001954) |
| 0.1 | 4.4 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.1 | 0.7 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
| 0.1 | 0.7 | GO:0048291 | isotype switching to IgG isotypes(GO:0048291) |
| 0.1 | 1.3 | GO:0070586 | cell-cell adhesion involved in gastrulation(GO:0070586) |
| 0.1 | 1.8 | GO:0061050 | regulation of cell growth involved in cardiac muscle cell development(GO:0061050) |
| 0.1 | 3.1 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.1 | 2.5 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.1 | 1.8 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.1 | 1.7 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) |
| 0.1 | 2.1 | GO:0002076 | osteoblast development(GO:0002076) |
| 0.1 | 0.7 | GO:0009099 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
| 0.1 | 4.3 | GO:0032330 | regulation of chondrocyte differentiation(GO:0032330) |
| 0.1 | 4.3 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.1 | 2.5 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.1 | 1.3 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.1 | 0.6 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.1 | 1.2 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
| 0.1 | 3.6 | GO:0033344 | cholesterol efflux(GO:0033344) |
| 0.1 | 0.2 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.1 | 1.3 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 0.1 | 1.2 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.1 | 6.5 | GO:0016573 | histone acetylation(GO:0016573) |
| 0.1 | 2.1 | GO:0048147 | negative regulation of fibroblast proliferation(GO:0048147) |
| 0.1 | 0.6 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 0.3 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) |
| 0.1 | 1.5 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 2.6 | GO:0050710 | negative regulation of cytokine secretion(GO:0050710) |
| 0.1 | 8.2 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.1 | 2.8 | GO:0051384 | response to glucocorticoid(GO:0051384) |
| 0.1 | 1.5 | GO:0030539 | male genitalia development(GO:0030539) |
| 0.1 | 1.9 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.1 | 4.4 | GO:0006413 | translational initiation(GO:0006413) |
| 0.1 | 0.2 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
| 0.0 | 3.8 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 0.6 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
| 0.0 | 0.2 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.0 | 1.4 | GO:0060122 | inner ear receptor stereocilium organization(GO:0060122) |
| 0.0 | 1.0 | GO:0031069 | hair follicle morphogenesis(GO:0031069) |
| 0.0 | 0.2 | GO:0070897 | DNA-templated transcriptional preinitiation complex assembly(GO:0070897) |
| 0.0 | 0.9 | GO:0022038 | corpus callosum development(GO:0022038) |
| 0.0 | 2.4 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.0 | 3.1 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.2 | GO:0097503 | sialylation(GO:0097503) |
| 0.0 | 0.1 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.2 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 0.0 | 0.3 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 0.0 | 2.0 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
| 0.0 | 1.1 | GO:0010212 | response to ionizing radiation(GO:0010212) |
| 0.0 | 0.7 | GO:0018196 | peptidyl-asparagine modification(GO:0018196) |
| 0.0 | 0.2 | GO:0006047 | UDP-N-acetylglucosamine metabolic process(GO:0006047) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 20.3 | 121.6 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 16.5 | 264.8 | GO:0042555 | MCM complex(GO:0042555) |
| 11.9 | 35.7 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 11.2 | 44.9 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 7.6 | 60.4 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 7.5 | 60.2 | GO:0008091 | spectrin(GO:0008091) |
| 6.5 | 39.3 | GO:0031523 | Myb complex(GO:0031523) |
| 6.4 | 38.2 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 5.6 | 66.7 | GO:0000796 | condensin complex(GO:0000796) |
| 5.5 | 16.5 | GO:1990423 | RZZ complex(GO:1990423) |
| 5.4 | 54.3 | GO:0042382 | paraspeckles(GO:0042382) |
| 5.1 | 20.4 | GO:0001740 | Barr body(GO:0001740) |
| 5.0 | 35.1 | GO:0005638 | lamin filament(GO:0005638) |
| 4.9 | 19.7 | GO:0008275 | gamma-tubulin small complex(GO:0008275) |
| 4.7 | 14.1 | GO:0000811 | GINS complex(GO:0000811) |
| 4.5 | 31.6 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 4.5 | 45.0 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 4.3 | 12.8 | GO:1990879 | CST complex(GO:1990879) |
| 4.2 | 12.5 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 4.0 | 23.9 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 3.7 | 11.2 | GO:1990031 | pinceau fiber(GO:1990031) |
| 3.5 | 14.0 | GO:0071920 | cleavage body(GO:0071920) |
| 3.4 | 40.8 | GO:0000801 | central element(GO:0000801) |
| 3.3 | 19.7 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 3.2 | 16.0 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 3.2 | 16.0 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 3.2 | 28.5 | GO:0045298 | tubulin complex(GO:0045298) |
| 3.1 | 12.4 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 3.0 | 5.9 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 2.9 | 14.7 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 2.9 | 20.5 | GO:0098536 | deuterosome(GO:0098536) |
| 2.9 | 2.9 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
| 2.9 | 31.4 | GO:0097451 | glial limiting end-foot(GO:0097451) |
| 2.8 | 8.5 | GO:0070877 | microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095) |
| 2.8 | 14.2 | GO:0061673 | mitotic spindle astral microtubule(GO:0061673) |
| 2.7 | 8.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 2.4 | 7.3 | GO:0005673 | transcription factor TFIIE complex(GO:0005673) |
| 2.3 | 16.4 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 2.3 | 20.9 | GO:0070652 | HAUS complex(GO:0070652) |
| 2.3 | 9.1 | GO:1990037 | Lewy body core(GO:1990037) |
| 2.3 | 9.1 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
| 2.2 | 31.5 | GO:0005652 | nuclear lamina(GO:0005652) |
| 2.2 | 17.8 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 2.2 | 22.1 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 2.2 | 23.8 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 2.2 | 135.8 | GO:0005657 | replication fork(GO:0005657) |
| 2.0 | 24.0 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 2.0 | 5.9 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
| 1.9 | 23.3 | GO:0034709 | methylosome(GO:0034709) |
| 1.9 | 9.7 | GO:0043293 | apoptosome(GO:0043293) |
| 1.9 | 5.7 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 1.8 | 16.6 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 1.8 | 21.2 | GO:0000974 | Prp19 complex(GO:0000974) |
| 1.7 | 32.6 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 1.7 | 20.5 | GO:0001739 | sex chromatin(GO:0001739) |
| 1.7 | 8.5 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 1.7 | 11.8 | GO:0097513 | myosin II filament(GO:0097513) |
| 1.7 | 5.0 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 1.6 | 21.9 | GO:0005688 | U6 snRNP(GO:0005688) |
| 1.5 | 8.8 | GO:0070876 | SOSS complex(GO:0070876) |
| 1.3 | 14.5 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 1.3 | 11.8 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 1.3 | 75.4 | GO:0015030 | Cajal body(GO:0015030) |
| 1.3 | 7.6 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 1.2 | 13.7 | GO:0000228 | nuclear chromosome(GO:0000228) |
| 1.2 | 6.1 | GO:0030870 | Mre11 complex(GO:0030870) |
| 1.2 | 11.0 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 1.2 | 11.6 | GO:0061574 | ASAP complex(GO:0061574) |
| 1.2 | 6.9 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 1.1 | 46.6 | GO:0051233 | spindle midzone(GO:0051233) |
| 1.1 | 5.6 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 1.1 | 5.6 | GO:0071953 | elastic fiber(GO:0071953) |
| 1.1 | 13.2 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 1.1 | 15.2 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 1.1 | 21.6 | GO:0044453 | nuclear membrane part(GO:0044453) |
| 1.1 | 66.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 1.1 | 19.4 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 1.1 | 11.7 | GO:0031415 | NatA complex(GO:0031415) |
| 1.1 | 11.7 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 1.1 | 9.5 | GO:0032797 | SMN complex(GO:0032797) |
| 1.0 | 16.4 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 1.0 | 9.2 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 1.0 | 10.8 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 1.0 | 5.8 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 1.0 | 6.7 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 1.0 | 4.8 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 0.9 | 11.9 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.9 | 5.3 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.9 | 3.5 | GO:0071014 | U2-type post-mRNA release spliceosomal complex(GO:0071008) post-mRNA release spliceosomal complex(GO:0071014) |
| 0.8 | 4.2 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.8 | 9.9 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.8 | 6.6 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.8 | 52.8 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.8 | 12.8 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.7 | 7.5 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.7 | 2.9 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.7 | 5.1 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.7 | 9.4 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.7 | 6.5 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.7 | 2.1 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.7 | 54.9 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.7 | 18.1 | GO:0045120 | pronucleus(GO:0045120) |
| 0.7 | 28.5 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.7 | 13.2 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.7 | 7.5 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.7 | 4.0 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.7 | 32.4 | GO:0030673 | axolemma(GO:0030673) |
| 0.7 | 21.1 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.6 | 41.1 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.6 | 60.4 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.6 | 3.7 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.6 | 3.1 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.6 | 4.9 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.6 | 7.3 | GO:0031264 | death-inducing signaling complex(GO:0031264) |
| 0.6 | 9.0 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.6 | 5.3 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.6 | 7.7 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.6 | 4.7 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.6 | 8.7 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.6 | 9.8 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.6 | 17.6 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.6 | 6.8 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.6 | 17.7 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.6 | 2.8 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.6 | 9.9 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.5 | 5.5 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.5 | 2.7 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.5 | 3.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.5 | 3.7 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.5 | 10.5 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.5 | 51.7 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.5 | 2.0 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.5 | 2.5 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.5 | 82.1 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.5 | 2.0 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.5 | 8.6 | GO:0036038 | MKS complex(GO:0036038) |
| 0.5 | 5.7 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.5 | 26.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.5 | 4.2 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
| 0.5 | 11.2 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
| 0.5 | 7.9 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.5 | 4.1 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.4 | 4.5 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.4 | 6.7 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.4 | 3.5 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.4 | 10.7 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.4 | 1.2 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.4 | 3.9 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.4 | 16.5 | GO:0008305 | integrin complex(GO:0008305) |
| 0.4 | 2.6 | GO:0097433 | dense body(GO:0097433) |
| 0.4 | 7.0 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.4 | 1.1 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.4 | 14.0 | GO:0016592 | mediator complex(GO:0016592) |
| 0.4 | 3.2 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.4 | 4.3 | GO:0090533 | cation-transporting ATPase complex(GO:0090533) |
| 0.4 | 5.7 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.4 | 3.5 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.3 | 21.9 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.3 | 6.0 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.3 | 14.6 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.3 | 3.2 | GO:0010369 | chromocenter(GO:0010369) |
| 0.3 | 1.3 | GO:0005606 | laminin-1 complex(GO:0005606) laminin-3 complex(GO:0005608) |
| 0.3 | 1.6 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 0.3 | 9.3 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.3 | 15.2 | GO:0002102 | podosome(GO:0002102) |
| 0.3 | 5.4 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.3 | 1.8 | GO:0016589 | NURF complex(GO:0016589) |
| 0.3 | 4.1 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.3 | 3.8 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.3 | 4.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.3 | 8.1 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.3 | 16.4 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.3 | 34.9 | GO:0032432 | actin filament bundle(GO:0032432) |
| 0.3 | 88.8 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.3 | 1.4 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.3 | 8.6 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.3 | 27.7 | GO:0005811 | lipid particle(GO:0005811) |
| 0.3 | 4.1 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.3 | 6.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.3 | 6.5 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.3 | 5.6 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.3 | 28.1 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.3 | 6.0 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.3 | 7.1 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.3 | 21.5 | GO:0016605 | PML body(GO:0016605) |
| 0.2 | 2.2 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.2 | 24.1 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.2 | 2.5 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.2 | 1.6 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 0.2 | 1.0 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 0.2 | 5.3 | GO:0030904 | retromer complex(GO:0030904) |
| 0.2 | 1.4 | GO:0008274 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 0.2 | 1.5 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.2 | 0.9 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.2 | 11.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.2 | 2.0 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 0.2 | 2.6 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.2 | 4.0 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.2 | 2.6 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.1 | 2.3 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 11.7 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.1 | 20.3 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.1 | 2.2 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.1 | 2.8 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.1 | 1.5 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 1.4 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.1 | 1.5 | GO:0031091 | platelet alpha granule(GO:0031091) |
| 0.1 | 9.2 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 1.9 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 5.4 | GO:0016235 | aggresome(GO:0016235) |
| 0.1 | 0.9 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 26.4 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.1 | 0.9 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.1 | 0.9 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.1 | 3.4 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 0.6 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.1 | 5.4 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 0.2 | GO:0090576 | RNA polymerase III transcription factor complex(GO:0090576) |
| 0.1 | 2.4 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 2.4 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 4.9 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 0.5 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
| 0.1 | 1.5 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 1.1 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 11.3 | GO:0001726 | ruffle(GO:0001726) |
| 0.1 | 0.9 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.1 | 1.7 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.1 | 0.5 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.1 | 2.6 | GO:0016591 | DNA-directed RNA polymerase II, holoenzyme(GO:0016591) |
| 0.1 | 13.5 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 3.3 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 0.7 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.0 | 9.9 | GO:0005694 | chromosome(GO:0005694) |
| 0.0 | 11.7 | GO:0043292 | contractile fiber(GO:0043292) |
| 0.0 | 5.2 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 1.2 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.8 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 0.7 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 3.1 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.4 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 0.8 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 0.1 | GO:0031501 | mannosyltransferase complex(GO:0031501) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 22.5 | 67.6 | GO:0052895 | norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895) |
| 20.3 | 121.6 | GO:0016728 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 14.9 | 44.8 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 11.7 | 35.1 | GO:0003896 | DNA primase activity(GO:0003896) |
| 11.5 | 92.0 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
| 10.2 | 51.0 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 9.4 | 28.1 | GO:0042602 | riboflavin reductase (NADPH) activity(GO:0042602) |
| 6.4 | 19.1 | GO:0004418 | hydroxymethylbilane synthase activity(GO:0004418) |
| 6.1 | 18.2 | GO:0004615 | phosphomannomutase activity(GO:0004615) |
| 6.0 | 17.9 | GO:0004088 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 5.7 | 5.7 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 5.6 | 22.5 | GO:0008493 | tetracycline transporter activity(GO:0008493) |
| 5.3 | 16.0 | GO:0031753 | endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755) |
| 4.8 | 9.5 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 4.5 | 17.8 | GO:0071207 | histone pre-mRNA stem-loop binding(GO:0071207) |
| 4.4 | 53.2 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 4.4 | 26.6 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 4.3 | 187.8 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 4.2 | 12.5 | GO:0004798 | thymidylate kinase activity(GO:0004798) |
| 4.2 | 20.8 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 4.0 | 43.9 | GO:0043142 | single-stranded DNA-dependent ATPase activity(GO:0043142) |
| 4.0 | 16.0 | GO:0030519 | snoRNP binding(GO:0030519) |
| 3.9 | 11.6 | GO:0004611 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 3.6 | 25.2 | GO:0043515 | kinetochore binding(GO:0043515) |
| 3.6 | 14.2 | GO:0032357 | guanine/thymine mispair binding(GO:0032137) oxidized purine DNA binding(GO:0032357) |
| 3.4 | 30.3 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 3.3 | 26.7 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 3.1 | 31.2 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 3.0 | 60.6 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 2.9 | 11.5 | GO:0004329 | formate-tetrahydrofolate ligase activity(GO:0004329) |
| 2.9 | 31.5 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 2.8 | 14.2 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 2.8 | 14.0 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
| 2.7 | 10.9 | GO:0004938 | alpha2-adrenergic receptor activity(GO:0004938) |
| 2.7 | 21.8 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 2.6 | 7.7 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 2.5 | 7.6 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 2.5 | 35.2 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 2.4 | 36.6 | GO:0043047 | single-stranded telomeric DNA binding(GO:0043047) |
| 2.4 | 11.9 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 2.3 | 18.6 | GO:0051425 | PTB domain binding(GO:0051425) |
| 2.3 | 11.5 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 2.2 | 2.2 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 2.2 | 13.4 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 2.2 | 22.2 | GO:0004064 | arylesterase activity(GO:0004064) |
| 2.2 | 22.1 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 2.2 | 13.2 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 2.2 | 15.1 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 2.1 | 8.3 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 2.1 | 8.3 | GO:0070137 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 2.1 | 4.1 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) |
| 2.0 | 8.2 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 2.0 | 14.3 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 2.0 | 21.7 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 2.0 | 82.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 1.9 | 5.8 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 1.9 | 5.8 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 1.9 | 11.5 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 1.9 | 11.4 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 1.9 | 5.6 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 1.8 | 44.1 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 1.7 | 10.3 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 1.7 | 8.5 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 1.7 | 40.5 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 1.7 | 5.0 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 1.7 | 21.5 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 1.6 | 32.7 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 1.6 | 4.8 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 1.6 | 4.7 | GO:0032129 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 1.5 | 4.6 | GO:0098640 | integrin binding involved in cell-matrix adhesion(GO:0098640) |
| 1.5 | 13.5 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 1.5 | 4.4 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 1.5 | 11.8 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 1.4 | 47.8 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 1.4 | 4.3 | GO:0019797 | procollagen-proline 3-dioxygenase activity(GO:0019797) |
| 1.4 | 10.0 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
| 1.4 | 8.4 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 1.4 | 20.6 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 1.4 | 13.6 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 1.4 | 5.4 | GO:0048495 | Roundabout binding(GO:0048495) |
| 1.3 | 9.4 | GO:0031750 | D3 dopamine receptor binding(GO:0031750) |
| 1.3 | 12.1 | GO:0050897 | cobalt ion binding(GO:0050897) |
| 1.3 | 5.4 | GO:0042978 | ornithine decarboxylase activator activity(GO:0042978) |
| 1.3 | 18.5 | GO:0032552 | deoxyribonucleotide binding(GO:0032552) |
| 1.3 | 11.9 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
| 1.3 | 3.8 | GO:0042895 | antibiotic transporter activity(GO:0042895) |
| 1.3 | 5.1 | GO:0071796 | K6-linked polyubiquitin binding(GO:0071796) |
| 1.3 | 5.0 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 1.3 | 6.3 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 1.3 | 32.6 | GO:0035173 | histone kinase activity(GO:0035173) |
| 1.3 | 18.8 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 1.2 | 6.2 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
| 1.2 | 3.7 | GO:0001096 | TFIIF-class transcription factor binding(GO:0001096) |
| 1.2 | 8.4 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
| 1.2 | 15.6 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 1.2 | 9.6 | GO:0015099 | nickel cation transmembrane transporter activity(GO:0015099) |
| 1.2 | 4.7 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 1.2 | 3.5 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
| 1.2 | 6.9 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 1.1 | 12.3 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 1.1 | 48.8 | GO:0030506 | ankyrin binding(GO:0030506) |
| 1.1 | 5.5 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 1.1 | 29.7 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 1.1 | 12.0 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 1.1 | 10.8 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 1.1 | 14.0 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 1.1 | 3.2 | GO:0070878 | primary miRNA binding(GO:0070878) |
| 1.0 | 12.4 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 1.0 | 16.3 | GO:0031386 | protein tag(GO:0031386) |
| 1.0 | 60.9 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 1.0 | 4.0 | GO:0045183 | translation factor activity, non-nucleic acid binding(GO:0045183) |
| 1.0 | 24.8 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 1.0 | 29.8 | GO:0043274 | phospholipase binding(GO:0043274) |
| 1.0 | 3.0 | GO:0030116 | glial cell-derived neurotrophic factor receptor binding(GO:0030116) |
| 0.9 | 4.7 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.9 | 39.2 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.9 | 5.4 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.9 | 30.8 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.8 | 6.6 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.8 | 9.0 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.8 | 3.2 | GO:0038025 | reelin receptor activity(GO:0038025) |
| 0.8 | 7.2 | GO:0043559 | insulin binding(GO:0043559) |
| 0.8 | 62.8 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.8 | 4.0 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.8 | 0.8 | GO:0035870 | dITP diphosphatase activity(GO:0035870) |
| 0.8 | 26.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.8 | 7.7 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.8 | 12.3 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.8 | 6.9 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.7 | 5.1 | GO:0055104 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 0.7 | 34.4 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.7 | 8.6 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 0.7 | 10.7 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
| 0.7 | 9.9 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.7 | 8.3 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.7 | 14.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.7 | 6.6 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 0.6 | 20.0 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.6 | 4.5 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.6 | 1.8 | GO:0004962 | endothelin receptor activity(GO:0004962) |
| 0.6 | 16.6 | GO:0031005 | filamin binding(GO:0031005) |
| 0.6 | 6.1 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.6 | 3.0 | GO:1990188 | euchromatin binding(GO:1990188) |
| 0.6 | 1.8 | GO:0019002 | GMP binding(GO:0019002) |
| 0.6 | 4.1 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 0.6 | 9.4 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.6 | 14.1 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.6 | 4.7 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.6 | 2.9 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.6 | 8.0 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
| 0.6 | 1.7 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.5 | 3.3 | GO:0001602 | pancreatic polypeptide receptor activity(GO:0001602) |
| 0.5 | 3.3 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.5 | 12.0 | GO:0010181 | FMN binding(GO:0010181) |
| 0.5 | 57.0 | GO:0004386 | helicase activity(GO:0004386) |
| 0.5 | 19.4 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.5 | 26.2 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.5 | 5.3 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.5 | 28.6 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.5 | 7.2 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.5 | 59.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.5 | 3.1 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.5 | 2.0 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.5 | 4.6 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.5 | 5.1 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.5 | 96.9 | GO:0042393 | histone binding(GO:0042393) |
| 0.5 | 3.9 | GO:0048019 | receptor antagonist activity(GO:0048019) |
| 0.5 | 6.2 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.5 | 5.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.5 | 9.9 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.5 | 4.2 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.5 | 4.1 | GO:0005113 | patched binding(GO:0005113) |
| 0.5 | 26.5 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.5 | 9.1 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.5 | 3.2 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.5 | 1.8 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.4 | 6.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.4 | 2.1 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.4 | 22.5 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.4 | 11.2 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.4 | 8.6 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.4 | 2.8 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.4 | 1.6 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.4 | 2.4 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.4 | 2.4 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 0.4 | 19.0 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.4 | 5.8 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.4 | 9.9 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.4 | 3.8 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.4 | 3.8 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.4 | 15.3 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.4 | 4.8 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.4 | 5.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.4 | 4.0 | GO:0070739 | protein-glutamic acid ligase activity(GO:0070739) |
| 0.4 | 2.5 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.4 | 12.5 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.3 | 1.7 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.3 | 24.4 | GO:0070888 | E-box binding(GO:0070888) |
| 0.3 | 2.0 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 0.3 | 4.0 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.3 | 1.7 | GO:0070548 | L-glutamine aminotransferase activity(GO:0070548) |
| 0.3 | 2.3 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 0.3 | 14.2 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.3 | 4.8 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.3 | 3.5 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 0.3 | 19.9 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.3 | 7.4 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.3 | 2.8 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.3 | 27.7 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.3 | 7.2 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.3 | 1.2 | GO:0003696 | satellite DNA binding(GO:0003696) |
| 0.3 | 2.4 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.3 | 1.2 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
| 0.3 | 1.1 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.3 | 8.6 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.3 | 5.4 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.3 | 15.0 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.3 | 15.7 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.3 | 3.9 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.3 | 22.0 | GO:0051287 | NAD binding(GO:0051287) |
| 0.3 | 1.3 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.3 | 0.8 | GO:1990931 | oxidative DNA demethylase activity(GO:0035516) RNA N6-methyladenosine dioxygenase activity(GO:1990931) |
| 0.3 | 2.6 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.3 | 1.0 | GO:0051022 | Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.2 | 3.4 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.2 | 8.5 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.2 | 10.7 | GO:0043531 | ADP binding(GO:0043531) |
| 0.2 | 4.1 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.2 | 5.8 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.2 | 0.6 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 0.2 | 3.6 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.2 | 41.1 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.2 | 13.7 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.2 | 37.7 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.2 | 8.6 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.2 | 21.0 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.2 | 0.9 | GO:0045340 | mercury ion binding(GO:0045340) |
| 0.2 | 6.0 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.2 | 0.7 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.2 | 1.4 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.2 | 0.7 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
| 0.2 | 1.0 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 0.2 | 1.7 | GO:1990446 | snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446) |
| 0.2 | 1.2 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.2 | 1.2 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.2 | 1.3 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.2 | 7.4 | GO:0019003 | GDP binding(GO:0019003) |
| 0.2 | 3.2 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.2 | 5.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.2 | 5.3 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.2 | 4.5 | GO:0003954 | NADH dehydrogenase activity(GO:0003954) |
| 0.1 | 1.2 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.1 | 8.5 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.1 | 2.9 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 4.0 | GO:0016866 | intramolecular transferase activity(GO:0016866) |
| 0.1 | 5.5 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.1 | 0.9 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 3.3 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 3.4 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.1 | 3.4 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 0.8 | GO:0000828 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.1 | 0.9 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.1 | 6.5 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.1 | 7.1 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.1 | 11.0 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.1 | 5.2 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 18.0 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.1 | 4.0 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 2.5 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 10.6 | GO:0031072 | heat shock protein binding(GO:0031072) |
| 0.1 | 1.6 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 7.5 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.1 | 8.1 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.1 | 1.8 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 2.3 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 33.4 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.1 | 6.9 | GO:0015370 | solute:sodium symporter activity(GO:0015370) |
| 0.1 | 0.7 | GO:0004084 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.1 | 1.4 | GO:0016278 | lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279) |
| 0.1 | 3.5 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 0.7 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.1 | 2.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 0.4 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.1 | 1.0 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 9.1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 0.5 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.1 | 1.7 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 1.5 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 1.1 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 3.1 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 15.8 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 0.2 | GO:0000995 | transcription factor activity, core RNA polymerase binding(GO:0000990) transcription factor activity, core RNA polymerase III binding(GO:0000995) transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007) |
| 0.0 | 1.8 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.3 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.0 | 0.2 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.0 | 1.7 | GO:0016763 | transferase activity, transferring pentosyl groups(GO:0016763) |
| 0.0 | 2.0 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 39.8 | GO:0003723 | RNA binding(GO:0003723) |
| 0.0 | 1.3 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 2.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 13.2 | GO:0008270 | zinc ion binding(GO:0008270) |
| 0.0 | 3.3 | GO:0019902 | phosphatase binding(GO:0019902) |
| 0.0 | 0.2 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.0 | 0.8 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.4 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.3 | 291.0 | PID ATR PATHWAY | ATR signaling pathway |
| 3.0 | 341.0 | PID E2F PATHWAY | E2F transcription factor network |
| 2.4 | 9.5 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 2.2 | 123.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 1.7 | 26.6 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 1.4 | 49.1 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 1.4 | 11.5 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 1.0 | 12.1 | PID MYC PATHWAY | C-MYC pathway |
| 1.0 | 15.8 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 1.0 | 19.3 | PID ATM PATHWAY | ATM pathway |
| 1.0 | 117.6 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.9 | 26.6 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.9 | 31.9 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.8 | 38.5 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.7 | 23.3 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.6 | 21.4 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.6 | 12.3 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.6 | 13.5 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.6 | 11.4 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.6 | 8.2 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.6 | 2.2 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.6 | 16.6 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.5 | 5.3 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.5 | 14.9 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.5 | 39.4 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.5 | 9.3 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.5 | 6.9 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.5 | 23.4 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.5 | 24.8 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.4 | 7.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.4 | 21.3 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.4 | 19.2 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.4 | 19.8 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.4 | 13.2 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.4 | 19.5 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.3 | 5.6 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.3 | 8.2 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.3 | 4.9 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.3 | 6.9 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.3 | 3.9 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.3 | 2.0 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.2 | 9.6 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.2 | 2.1 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.2 | 4.3 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.2 | 3.4 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.2 | 3.4 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.2 | 3.8 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.2 | 4.5 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.2 | 9.8 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.2 | 12.5 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.2 | 2.4 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.2 | 4.5 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.1 | 3.2 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.1 | 1.5 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.1 | 6.9 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 13.4 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.1 | 2.8 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 10.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 9.1 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 2.2 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.1 | 4.8 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 6.0 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.1 | 2.5 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.1 | 6.4 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.1 | 0.5 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 4.1 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.1 | 2.7 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 2.1 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.7 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 0.4 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.9 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.6 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 0.5 | PID BMP PATHWAY | BMP receptor signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 16.9 | 269.7 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 6.5 | 150.2 | REACTOME DNA STRAND ELONGATION | Genes involved in DNA strand elongation |
| 6.2 | 136.9 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 5.0 | 89.9 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 4.7 | 88.7 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 3.2 | 16.0 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 3.2 | 9.5 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 3.0 | 51.0 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 2.7 | 32.8 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 2.7 | 56.8 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 2.3 | 30.3 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 2.1 | 62.6 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 2.0 | 32.3 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 2.0 | 24.0 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 2.0 | 21.9 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 2.0 | 47.2 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 1.9 | 44.8 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 1.9 | 69.7 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 1.9 | 30.2 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 1.8 | 39.8 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 1.8 | 75.5 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 1.7 | 6.9 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 1.6 | 25.6 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 1.5 | 5.9 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 1.5 | 67.2 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 1.4 | 24.2 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 1.3 | 68.2 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 1.2 | 30.0 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 1.2 | 39.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 1.2 | 77.5 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 1.1 | 34.5 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 1.1 | 7.5 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 1.1 | 8.5 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 1.0 | 19.9 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.9 | 33.6 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.9 | 106.4 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.7 | 19.4 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.7 | 18.2 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.7 | 9.3 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.7 | 13.5 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.7 | 13.2 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.7 | 21.8 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.7 | 23.7 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.7 | 5.4 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.6 | 53.4 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.6 | 48.5 | REACTOME MITOTIC G2 G2 M PHASES | Genes involved in Mitotic G2-G2/M phases |
| 0.6 | 24.5 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.6 | 5.0 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.6 | 10.9 | REACTOME PLATELET AGGREGATION PLUG FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 0.6 | 7.2 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.5 | 13.0 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.5 | 7.4 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.5 | 6.2 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.5 | 6.1 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.5 | 7.5 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.5 | 25.9 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.5 | 7.0 | REACTOME RNA POL I TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |
| 0.5 | 5.1 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.4 | 3.1 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.4 | 5.3 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.4 | 24.4 | REACTOME REGULATION OF APOPTOSIS | Genes involved in Regulation of Apoptosis |
| 0.4 | 11.0 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.4 | 19.9 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.4 | 5.0 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.4 | 1.5 | REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
| 0.4 | 8.5 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.4 | 4.4 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 0.4 | 3.2 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.4 | 11.4 | REACTOME CHROMOSOME MAINTENANCE | Genes involved in Chromosome Maintenance |
| 0.3 | 30.6 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.3 | 3.2 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.3 | 6.8 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.3 | 8.5 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.3 | 10.5 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.3 | 2.5 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.3 | 12.6 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.3 | 8.2 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.3 | 11.8 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.2 | 4.0 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.2 | 18.6 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.2 | 14.1 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.2 | 11.3 | REACTOME LATE PHASE OF HIV LIFE CYCLE | Genes involved in Late Phase of HIV Life Cycle |
| 0.2 | 1.2 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.2 | 4.5 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.2 | 13.6 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.2 | 2.9 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.2 | 0.4 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.2 | 11.5 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.2 | 1.8 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.2 | 2.2 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.2 | 14.4 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.2 | 0.8 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.2 | 2.5 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.2 | 15.0 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.1 | 3.8 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.1 | 2.5 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.1 | 4.3 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.1 | 1.3 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.1 | 3.1 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 5.0 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 5.0 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 6.0 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.1 | 2.3 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.1 | 2.3 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.1 | 1.1 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.1 | 2.0 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.1 | 0.6 | REACTOME OPSINS | Genes involved in Opsins |
| 0.1 | 2.4 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 2.2 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.8 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 0.6 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 0.6 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.7 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.4 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |