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GSE58827: Dynamics of the Mouse Liver

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Results for E2f3

Z-value: 1.61

Motif logo

Transcription factors associated with E2f3

Gene Symbol Gene ID Gene Info
ENSMUSG00000016477.19 E2F transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f3mm39_v1_chr13_-_30170031_301700480.937.5e-16Click!

Activity profile of E2f3 motif

Sorted Z-values of E2f3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_6733411 13.70 ENSMUST00000239104.2
ENSMUST00000051209.11
paternally expressed 3
chr3_-_84387700 12.85 ENSMUST00000194027.2
ENSMUST00000107689.7
FH2 domain containing 1
chr2_+_117942357 12.51 ENSMUST00000039559.9
thrombospondin 1
chr2_-_126975804 10.48 ENSMUST00000110387.4
non-SMC condensin I complex, subunit H
chr12_+_24758968 9.68 ENSMUST00000154588.2
ribonucleotide reductase M2
chr11_+_11635908 9.37 ENSMUST00000065433.12
IKAROS family zinc finger 1
chr12_-_4924341 9.20 ENSMUST00000137337.8
ENSMUST00000045921.14
major facilitator superfamily domain containing 2B
chr12_-_69274936 8.29 ENSMUST00000221411.2
ENSMUST00000021359.7
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr12_+_24758724 8.11 ENSMUST00000153058.8
ribonucleotide reductase M2
chr5_-_113957362 8.06 ENSMUST00000202555.2
selectin, platelet (p-selectin) ligand
chr15_+_84116231 7.98 ENSMUST00000023072.7
parvin, beta
chr3_+_10077608 7.87 ENSMUST00000029046.9
fatty acid binding protein 5, epidermal
chr7_+_13012735 7.82 ENSMUST00000098814.13
ENSMUST00000146998.9
ligase I, DNA, ATP-dependent
chr12_+_24758240 7.70 ENSMUST00000020980.12
ribonucleotide reductase M2
chr10_+_20223516 7.54 ENSMUST00000169712.3
ENSMUST00000217608.2
mitochondrial fission regulator 2
chr4_+_43957401 7.49 ENSMUST00000030202.14
GLI pathogenesis-related 2
chr9_+_64188857 7.44 ENSMUST00000215031.2
ENSMUST00000213165.2
ENSMUST00000213289.2
ENSMUST00000216594.2
ENSMUST00000034964.7
timeless interacting protein
chr8_+_95712151 7.06 ENSMUST00000212799.2
adhesion G protein-coupled receptor G1
chr8_+_123294740 6.46 ENSMUST00000006760.3
chromatin licensing and DNA replication factor 1
chr5_-_113957318 6.38 ENSMUST00000201194.4
selectin, platelet (p-selectin) ligand
chr4_+_43957677 6.29 ENSMUST00000107855.2
GLI pathogenesis-related 2
chr4_-_140805613 5.92 ENSMUST00000030760.15
NECAP endocytosis associated 2
chr10_-_93425553 5.22 ENSMUST00000020203.7
small nuclear ribonucleoprotein polypeptide F
chr15_-_83479312 5.19 ENSMUST00000016901.5
tubulin tyrosine ligase-like family, member 12
chr5_-_148336711 5.07 ENSMUST00000048116.15
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chrX_-_101232978 4.92 ENSMUST00000033683.8
ribosomal protein S4, X-linked
chr5_-_68004743 4.45 ENSMUST00000072971.13
ENSMUST00000113652.8
ENSMUST00000113651.8
ENSMUST00000037380.15
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr15_-_79967543 4.23 ENSMUST00000081650.15
ribosomal protein L3
chr16_-_4536943 4.13 ENSMUST00000120056.8
ENSMUST00000074970.8
NmrA-like family domain containing 1
chr11_-_101442663 4.11 ENSMUST00000017290.11
breast cancer 1, early onset
chr16_-_4536992 4.06 ENSMUST00000115851.10
NmrA-like family domain containing 1
chr3_+_68912302 3.80 ENSMUST00000136502.8
ENSMUST00000107803.7
structural maintenance of chromosomes 4
chr2_+_150628655 3.68 ENSMUST00000045441.8
brain glycogen phosphorylase
chr4_+_132495636 3.67 ENSMUST00000102561.11
replication protein A2
chr11_+_115455260 3.58 ENSMUST00000021085.11
nucleoporin 85
chr2_+_150751475 3.55 ENSMUST00000028948.5
GINS complex subunit 1 (Psf1 homolog)
chr17_+_27136065 3.52 ENSMUST00000078961.6
kinesin family member C5B
chrX_+_20570145 3.48 ENSMUST00000033383.3
ubiquitin specific peptidase 11
chr4_+_109137561 3.43 ENSMUST00000177089.8
ENSMUST00000175776.8
ENSMUST00000132165.9
epidermal growth factor receptor pathway substrate 15
chr18_+_31922173 3.18 ENSMUST00000025106.5
ENSMUST00000234146.2
polymerase (RNA) II (DNA directed) polypeptide D
chr18_+_67933169 3.11 ENSMUST00000025425.7
centrosomal protein 192
chr17_-_71782296 3.11 ENSMUST00000127430.2
SMC hinge domain containing 1
chr10_-_80754016 3.11 ENSMUST00000057623.14
ENSMUST00000179022.8
lamin B2
chr5_-_36555434 3.04 ENSMUST00000037370.14
ENSMUST00000070720.8
sortilin-related VPS10 domain containing receptor 2
chr13_-_55477535 3.01 ENSMUST00000021941.8
Max dimerization protein 3
chr7_+_89779421 2.96 ENSMUST00000207225.2
ENSMUST00000207484.2
ENSMUST00000209068.2
phosphatidylinositol binding clathrin assembly protein
chr13_-_51947685 2.80 ENSMUST00000110040.9
ENSMUST00000021900.14
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr18_+_11790409 2.77 ENSMUST00000047322.8
retinoblastoma binding protein 8, endonuclease
chr8_-_124586159 2.76 ENSMUST00000034452.12
centriole, cilia and spindle associated protein
chr1_-_128287347 2.74 ENSMUST00000190495.2
ENSMUST00000027601.11
minichromosome maintenance complex component 6
chr2_+_109111083 2.65 ENSMUST00000028527.8
kinesin family member 18A
chr16_-_78173645 2.54 ENSMUST00000023570.14
BTG anti-proliferation factor 3
chr12_+_111505216 2.54 ENSMUST00000050993.11
eukaryotic translation initiation factor 5
chr5_-_65855511 2.45 ENSMUST00000201948.4
PDS5 cohesin associated factor A
chr8_+_106587212 2.43 ENSMUST00000008594.9
nuclear transport factor 2
chr12_+_111505253 2.34 ENSMUST00000220803.2
eukaryotic translation initiation factor 5
chr8_+_106587268 2.31 ENSMUST00000212610.2
ENSMUST00000212484.2
ENSMUST00000212200.2
nuclear transport factor 2
chr6_-_72322116 2.30 ENSMUST00000070345.5
ubiquitin specific peptidase 39
chr11_-_84020382 2.25 ENSMUST00000018795.13
transcriptional adaptor 2A
chr1_-_66902429 2.23 ENSMUST00000027153.6
acyl-Coenzyme A dehydrogenase, long-chain
chr8_-_57940834 2.22 ENSMUST00000034022.4
sin3 associated polypeptide
chr4_-_34614883 2.21 ENSMUST00000140334.2
ENSMUST00000108142.8
ENSMUST00000048706.10
origin recognition complex, subunit 3
chr8_-_120331936 2.20 ENSMUST00000093099.13
TATA-box binding protein associated factor, RNA polymerase I, C
chr4_+_109137462 2.18 ENSMUST00000102729.10
epidermal growth factor receptor pathway substrate 15
chrX_-_72703330 2.14 ENSMUST00000114473.8
ENSMUST00000002087.14
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr17_+_29251602 2.12 ENSMUST00000130216.3
serine and arginine-rich splicing factor 3
chr10_-_61619790 2.11 ENSMUST00000020283.5
macroH2A.2 histone
chr17_+_36152383 2.05 ENSMUST00000082337.13
mediator of DNA damage checkpoint 1
chr6_+_120440159 2.05 ENSMUST00000002976.5
interleukin 17 receptor A
chr8_+_95584146 2.01 ENSMUST00000211939.2
ENSMUST00000212124.2
polymerase (RNA) II (DNA directed) polypeptide C
chr5_-_100867520 2.00 ENSMUST00000112908.2
ENSMUST00000045617.15
heparanase
chr2_+_115412148 1.94 ENSMUST00000166472.8
ENSMUST00000110918.3
CDAN1 interacting nuclease 1
chr5_-_123038329 1.93 ENSMUST00000031435.14
lysine (K)-specific demethylase 2B
chr18_-_52662728 1.90 ENSMUST00000025409.9
lysyl oxidase
chr17_-_67661382 1.87 ENSMUST00000223982.2
ENSMUST00000224091.2
protein tyrosine phosphatase, receptor type, M
chr14_-_30348153 1.87 ENSMUST00000112211.9
ENSMUST00000112210.11
protein kinase C, delta
chr3_-_51248032 1.86 ENSMUST00000062009.14
ENSMUST00000194641.6
E74-like factor 2
chr19_+_53588808 1.85 ENSMUST00000025930.10
structural maintenance of chromosomes 3
chr13_-_21715202 1.84 ENSMUST00000156674.3
ENSMUST00000110481.3
ENSMUST00000045228.12
zinc finger with KRAB and SCAN domains 8
chr2_+_31560725 1.83 ENSMUST00000038474.14
ENSMUST00000137156.2
exosome component 2
chr16_+_91444730 1.81 ENSMUST00000119368.8
ENSMUST00000114037.9
ENSMUST00000114036.9
ENSMUST00000122302.8
Son DNA binding protein
chr1_-_191307648 1.71 ENSMUST00000027933.11
denticleless E3 ubiquitin protein ligase
chr4_+_11485945 1.71 ENSMUST00000055372.14
ENSMUST00000059914.13
vir like m6A methyltransferase associated
chr12_-_111638722 1.69 ENSMUST00000001304.9
creatine kinase, brain
chr12_+_111504450 1.67 ENSMUST00000166123.9
ENSMUST00000222441.2
eukaryotic translation initiation factor 5
chr12_+_86725459 1.67 ENSMUST00000021681.4
vasohibin 1
chr15_+_99870661 1.67 ENSMUST00000100206.4
La ribonucleoprotein domain family, member 4
chr4_+_34614939 1.66 ENSMUST00000029968.14
ENSMUST00000148519.3
arginyl-tRNA synthetase 2, mitochondrial
chr9_-_57673128 1.64 ENSMUST00000065330.8
CDC-like kinase 3
chr3_-_84063067 1.61 ENSMUST00000047368.8
meiotic nuclear divisions 1
chr8_+_95584078 1.61 ENSMUST00000109521.4
polymerase (RNA) II (DNA directed) polypeptide C
chr4_+_130202388 1.60 ENSMUST00000070532.8
fatty acid binding protein 3, muscle and heart
chr10_-_80512117 1.60 ENSMUST00000200082.5
MAP kinase-interacting serine/threonine kinase 2
chr2_+_32766126 1.59 ENSMUST00000028135.15
niban apoptosis regulator 2
chr5_-_68004702 1.59 ENSMUST00000135930.8
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr8_-_123303569 1.50 ENSMUST00000006764.9
adenine phosphoribosyl transferase
chr8_-_123303352 1.48 ENSMUST00000211823.2
ENSMUST00000212093.2
adenine phosphoribosyl transferase
chr8_-_70449018 1.42 ENSMUST00000065169.12
ENSMUST00000212478.2
GATA zinc finger domain containing 2A
chr4_-_108436514 1.42 ENSMUST00000079213.6
PRP38 pre-mRNA processing factor 38 (yeast) domain containing A
chr9_-_62888156 1.42 ENSMUST00000098651.6
ENSMUST00000214830.2
protein inhibitor of activated STAT 1
chr17_+_24633614 1.41 ENSMUST00000115371.9
ENSMUST00000088512.13
ENSMUST00000163717.2
RNA binding protein with serine rich domain 1
chr5_-_34093678 1.39 ENSMUST00000030993.8
negative elongation factor complex member A, Whsc2
chr12_+_80992294 1.38 ENSMUST00000110354.8
ENSMUST00000110352.10
ENSMUST00000110351.8
ENSMUST00000110356.3
serine and arginine-rich splicing factor 5
chr11_+_55104609 1.35 ENSMUST00000108867.2
solute carrier family 36 (proton/amino acid symporter), member 1
chr5_-_148336574 1.29 ENSMUST00000202457.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr9_-_39514931 1.29 ENSMUST00000119722.8
expressed sequence AW551984
chrX_-_104973003 1.28 ENSMUST00000130980.2
ENSMUST00000113573.8
ATRX, chromatin remodeler
chr1_+_127701901 1.26 ENSMUST00000112570.2
ENSMUST00000027587.15
cyclin T2
chr18_+_35252470 1.26 ENSMUST00000237154.2
catenin (cadherin associated protein), alpha 1
chr16_-_91443794 1.20 ENSMUST00000232367.2
ENSMUST00000231380.2
ENSMUST00000231444.2
ENSMUST00000232289.2
ENSMUST00000120450.2
ENSMUST00000023684.14
phosphoribosylglycinamide formyltransferase
chr9_+_56979307 1.19 ENSMUST00000169879.8
transcriptional regulator, SIN3A (yeast)
chr5_-_65855199 1.17 ENSMUST00000031104.7
PDS5 cohesin associated factor A
chr10_+_80062468 1.16 ENSMUST00000130260.2
PWWP domain containing 3A, DNA repair factor
chr4_+_11486002 1.16 ENSMUST00000108307.3
vir like m6A methyltransferase associated
chr10_+_80634488 1.15 ENSMUST00000151928.8
splicing factor 3a, subunit 2
chr10_+_75152705 1.12 ENSMUST00000105420.3
adenosine A2a receptor
chr6_-_97594498 1.12 ENSMUST00000113355.9
FERM domain containing 4B
chr16_+_91282121 1.11 ENSMUST00000023689.11
ENSMUST00000117748.8
interferon (alpha and beta) receptor 1
chr9_+_113760376 1.08 ENSMUST00000214095.2
ENSMUST00000116492.3
ENSMUST00000216558.2
upstream binding protein 1
chr18_+_44513547 1.07 ENSMUST00000202306.2
ENSMUST00000025350.10
decapping mRNA 2
chr19_+_38384428 1.07 ENSMUST00000054098.4
solute carrier family 35, member G1
chr12_-_21423607 1.07 ENSMUST00000064536.13
a disintegrin and metallopeptidase domain 17
chr17_-_80369626 1.06 ENSMUST00000184635.8
heterogeneous nuclear ribonucleoprotein L-like
chr3_-_95125002 1.03 ENSMUST00000107209.8
GA repeat binding protein, beta 2
chr2_-_179867605 1.03 ENSMUST00000015791.6
laminin, alpha 5
chr18_+_9957906 1.03 ENSMUST00000025137.9
THO complex 1
chr15_-_79430942 1.01 ENSMUST00000054014.9
ENSMUST00000229877.2
DEAD box helicase 17
chr10_-_30476658 1.00 ENSMUST00000019927.7
tRNA methyltransferase 11
chr3_-_65299967 1.00 ENSMUST00000119896.2
signal sequence receptor, gamma
chr8_-_70448872 1.00 ENSMUST00000177851.9
GATA zinc finger domain containing 2A
chr12_-_21423551 0.98 ENSMUST00000101551.10
a disintegrin and metallopeptidase domain 17
chr7_-_5016237 0.97 ENSMUST00000208944.2
Flt3 interacting zinc finger protein 1
chr3_-_41696906 0.91 ENSMUST00000026866.15
sodium channel and clathrin linker 1
chr10_+_33780993 0.89 ENSMUST00000169670.8
radial spoke head 4 homolog A (Chlamydomonas)
chr8_+_104837939 0.88 ENSMUST00000209911.2
cadherin 5
chr7_+_100021425 0.88 ENSMUST00000098259.11
ENSMUST00000051777.15
C2 calcium-dependent domain containing 3
chr15_+_99870787 0.87 ENSMUST00000231160.2
La ribonucleoprotein domain family, member 4
chr17_-_80369762 0.87 ENSMUST00000061331.14
heterogeneous nuclear ribonucleoprotein L-like
chr16_-_43709968 0.86 ENSMUST00000023387.14
queuine tRNA-ribosyltransferase accessory subunit 2
chr12_+_112112621 0.84 ENSMUST00000128402.3
kinesin family member 26A
chr1_+_156386414 0.82 ENSMUST00000166172.9
ENSMUST00000027888.13
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr17_-_48145466 0.81 ENSMUST00000066368.13
MyoD family inhibitor
chr3_+_66892979 0.80 ENSMUST00000162362.8
ENSMUST00000065074.14
ENSMUST00000065047.13
arginine/serine-rich coiled-coil 1
chr3_+_33854305 0.78 ENSMUST00000196139.5
ENSMUST00000200271.5
ENSMUST00000198529.5
ENSMUST00000117915.8
ENSMUST00000108210.9
ENSMUST00000196975.5
tetratricopeptide repeat domain 14
chr3_-_95125190 0.76 ENSMUST00000136139.8
GA repeat binding protein, beta 2
chr11_-_86435579 0.75 ENSMUST00000138810.3
ENSMUST00000058286.9
ENSMUST00000154617.8
ribosomal protein S6 kinase, polypeptide 1
chr4_+_116565784 0.74 ENSMUST00000138305.8
ENSMUST00000125671.8
ENSMUST00000130828.8
coiled-coil domain containing 163
chrX_-_104972938 0.74 ENSMUST00000198448.5
ENSMUST00000199233.5
ENSMUST00000134507.8
ENSMUST00000154866.8
ENSMUST00000128968.8
ENSMUST00000134381.8
ENSMUST00000150914.8
ATRX, chromatin remodeler
chr13_+_54722833 0.73 ENSMUST00000156024.2
ADP-ribosylation factor-like 10
chr6_-_88818832 0.72 ENSMUST00000032169.8
ankyrin repeat and BTB (POZ) domain containing 1
chr19_+_45006552 0.69 ENSMUST00000237043.2
ENSMUST00000178087.3
leucine zipper, putative tumor suppressor 2
chr11_+_60066681 0.67 ENSMUST00000102688.2
retinoic acid induced 1
chr13_-_21586858 0.64 ENSMUST00000117721.8
ENSMUST00000070785.16
ENSMUST00000116433.2
ENSMUST00000223831.2
ENSMUST00000116434.11
ENSMUST00000224820.2
zinc finger with KRAB and SCAN domains 3
chr5_+_8943943 0.62 ENSMUST00000196067.2
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr1_+_90531183 0.62 ENSMUST00000186750.2
COP9 signalosome subunit 8
chrX_-_72703652 0.61 ENSMUST00000114472.8
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr19_-_5416626 0.60 ENSMUST00000237167.2
BAF nuclear assembly factor 1
chr7_+_23781311 0.59 ENSMUST00000207002.2
ENSMUST00000068975.6
ENSMUST00000203854.3
zinc finger protein 180
chr11_-_20199359 0.59 ENSMUST00000050611.14
ENSMUST00000109596.8
ENSMUST00000162811.2
centrosomal protein 68
chrX_-_8042129 0.59 ENSMUST00000143984.2
TBC1 domain family, member 25
chr4_+_116565706 0.59 ENSMUST00000030452.13
ENSMUST00000106462.9
coiled-coil domain containing 163
chr12_-_69728572 0.57 ENSMUST00000183277.8
ENSMUST00000035773.14
SOS Ras/Rho guanine nucleotide exchange factor 2
chr14_-_55101505 0.52 ENSMUST00000142283.4
homeodomain leucine zipper-encoding gene
chr12_+_111504640 0.51 ENSMUST00000222375.2
ENSMUST00000222388.2
eukaryotic translation initiation factor 5
chr3_+_66893031 0.49 ENSMUST00000046542.13
ENSMUST00000162693.8
arginine/serine-rich coiled-coil 1
chr3_+_97920819 0.46 ENSMUST00000079812.8
notch 2
chr11_+_113539995 0.46 ENSMUST00000018805.15
component of oligomeric golgi complex 1
chr8_-_35432783 0.45 ENSMUST00000033929.6
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr1_-_135241429 0.45 ENSMUST00000134088.3
ENSMUST00000081104.10
translocase of inner mitochondrial membrane 17a
chr2_+_180240015 0.45 ENSMUST00000103059.2
collagen, type IX, alpha 3
chr16_+_12927547 0.44 ENSMUST00000023206.14
excision repair cross-complementing rodent repair deficiency, complementation group 4
chr11_-_62348599 0.44 ENSMUST00000127471.9
nuclear receptor co-repressor 1
chr16_+_91282183 0.41 ENSMUST00000129878.2
interferon (alpha and beta) receptor 1
chr7_+_140774962 0.41 ENSMUST00000047093.11
leucine rich repeat containing 56
chr11_+_65698001 0.40 ENSMUST00000071465.9
ENSMUST00000018491.8
zinc finger with KRAB and SCAN domains 6
chr15_+_99870714 0.37 ENSMUST00000230956.2
La ribonucleoprotein domain family, member 4
chr18_-_13074834 0.35 ENSMUST00000122175.8
ENSMUST00000142467.2
ENSMUST00000074352.11
oxysterol binding protein-like 1A
chr18_+_11790888 0.35 ENSMUST00000234499.2
retinoblastoma binding protein 8, endonuclease
chr1_-_4563821 0.35 ENSMUST00000191939.2
SRY (sex determining region Y)-box 17
chr9_+_55949141 0.35 ENSMUST00000114276.3
reticulocalbin 2
chr1_-_95595280 0.34 ENSMUST00000043336.11
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr12_-_21423524 0.34 ENSMUST00000232107.2
a disintegrin and metallopeptidase domain 17
chr18_-_84607615 0.33 ENSMUST00000125763.3
zinc finger protein 407
chr17_-_33007238 0.33 ENSMUST00000159086.10
zinc finger protein 871
chr9_-_78350486 0.32 ENSMUST00000070742.14
ENSMUST00000034898.14
cyclic GMP-AMP synthase
chr8_+_84626715 0.30 ENSMUST00000141158.8
adhesion G protein-coupled receptor L1
chr16_-_22258469 0.29 ENSMUST00000079601.13
ets variant 5
chr12_-_100865783 0.28 ENSMUST00000053668.10
G protein-coupled receptor 68
chr18_+_37637317 0.27 ENSMUST00000052179.8
protocadherin beta 20
chr17_+_28075495 0.25 ENSMUST00000233809.2
UHRF1 (ICBP90) binding protein 1
chr2_+_156154219 0.23 ENSMUST00000037096.9
cyclic nucleotide binding domain containing 2
chr10_+_43354807 0.23 ENSMUST00000167488.9
BEN domain containing 3
chr18_+_37544717 0.21 ENSMUST00000051126.4
protocadherin beta 10
chr18_+_47245204 0.21 ENSMUST00000234633.2
heat shock protein 1 (chaperonin 10), related sequence 1
chr2_+_34999497 0.17 ENSMUST00000028235.11
ENSMUST00000156933.8
ENSMUST00000028237.15
ENSMUST00000113032.8
centriolin
chr5_-_39801940 0.17 ENSMUST00000152057.2
ENSMUST00000053116.7
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr6_+_71808427 0.15 ENSMUST00000171057.2
inner membrane protein, mitochondrial
chr2_-_120183575 0.15 ENSMUST00000028752.8
ENSMUST00000102501.10
VPS39 HOPS complex subunit
chr3_+_41697046 0.14 ENSMUST00000120167.8
ENSMUST00000108065.9
ENSMUST00000146165.8
ENSMUST00000192193.6
ENSMUST00000119572.8
ENSMUST00000026867.14
ENSMUST00000026868.13
DNA segment, Chr 3, ERATO Doi 751, expressed
chrX_+_134739783 0.14 ENSMUST00000173804.8
ENSMUST00000113136.8
G protein-coupled receptor associated sorting protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.5 GO:0010752 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
3.1 9.4 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
2.9 14.4 GO:0050902 leukocyte adhesive activation(GO:0050902)
2.6 10.5 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
2.2 2.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
2.2 6.5 GO:0036034 mediator complex assembly(GO:0036034) DNA replication preinitiation complex assembly(GO:0071163) response to sorbitol(GO:0072708) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
2.0 8.0 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
1.7 8.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
1.5 7.4 GO:0048478 replication fork protection(GO:0048478)
1.3 11.4 GO:1902969 mitotic DNA replication(GO:1902969)
1.2 4.7 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
1.1 25.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
1.1 3.2 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
1.0 3.1 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.8 4.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.7 3.0 GO:0006168 adenine salvage(GO:0006168) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.7 6.7 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.7 2.8 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.7 2.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.5 5.6 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.5 3.0 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.5 1.9 GO:0021993 initiation of neural tube closure(GO:0021993)
0.5 1.9 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.5 1.8 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.4 3.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.4 1.3 GO:0019085 early viral transcription(GO:0019085)
0.4 1.7 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.4 7.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.4 2.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.4 1.6 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.4 2.4 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.4 6.4 GO:0015809 arginine transport(GO:0015809)
0.4 2.2 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.3 3.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.3 7.9 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.3 1.7 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.3 1.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.3 0.9 GO:0061511 centriole elongation(GO:0061511)
0.3 7.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 2.4 GO:0021995 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2 1.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 4.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 0.5 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.2 2.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.8 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.2 1.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 0.8 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.2 1.9 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.2 0.6 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 2.9 GO:0080009 mRNA methylation(GO:0080009)
0.2 0.6 GO:0019043 establishment of viral latency(GO:0019043)
0.2 1.3 GO:1904907 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.2 13.8 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.2 2.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 1.3 GO:0015808 L-alanine transport(GO:0015808)
0.2 2.8 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.2 1.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.7 GO:0019985 translesion synthesis(GO:0019985)
0.2 3.1 GO:0046599 regulation of centriole replication(GO:0046599)
0.2 1.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.4 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1 3.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 2.1 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 3.7 GO:0009251 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 1.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 1.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 5.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 4.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 7.5 GO:0000266 mitochondrial fission(GO:0000266)
0.1 2.7 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.4 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 1.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 1.3 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 0.6 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 0.8 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 1.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.3 GO:0060807 cardiogenic plate morphogenesis(GO:0003142) regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification(GO:0060807) regulation of cardiac cell fate specification(GO:2000043)
0.1 1.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 1.6 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 1.9 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.1 0.9 GO:0001955 blood vessel maturation(GO:0001955)
0.1 3.6 GO:0048246 macrophage chemotaxis(GO:0048246)
0.1 1.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 3.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 5.3 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.6 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.0 GO:0035802 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.3 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.8 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.4 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 2.9 GO:0045727 positive regulation of translation(GO:0045727)
0.0 2.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 1.0 GO:0001755 neural crest cell migration(GO:0001755)
0.0 1.0 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.7 GO:0006414 translational elongation(GO:0006414)
0.0 1.9 GO:0008033 tRNA processing(GO:0008033)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.9 GO:0003341 cilium movement(GO:0003341) axoneme assembly(GO:0035082)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 25.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
2.2 2.2 GO:0031261 nuclear pre-replicative complex(GO:0005656) DNA replication preinitiation complex(GO:0031261) pre-replicative complex(GO:0036387)
2.1 10.5 GO:0000799 nuclear condensin complex(GO:0000799)
1.7 8.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.5 7.4 GO:0031298 replication fork protection complex(GO:0031298)
1.4 12.5 GO:0005577 fibrinogen complex(GO:0005577)
1.2 3.5 GO:0000811 GINS complex(GO:0000811)
0.9 5.2 GO:0005683 U7 snRNP(GO:0005683)
0.8 14.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.8 3.1 GO:0001740 Barr body(GO:0001740)
0.6 7.1 GO:0097451 glial limiting end-foot(GO:0097451)
0.6 10.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.6 2.8 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.5 3.8 GO:0000796 condensin complex(GO:0000796)
0.4 2.2 GO:0000125 PCAF complex(GO:0000125)
0.4 3.1 GO:0005638 lamin filament(GO:0005638)
0.4 14.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.4 4.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.4 2.9 GO:0036396 MIS complex(GO:0036396)
0.4 4.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.4 2.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 1.4 GO:0032021 NELF complex(GO:0032021)
0.3 2.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.3 1.9 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.3 1.0 GO:0043259 laminin-10 complex(GO:0043259)
0.3 3.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 6.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 1.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.2 2.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 3.8 GO:0016580 Sin3 complex(GO:0016580)
0.2 2.7 GO:0042555 MCM complex(GO:0042555)
0.2 1.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.4 GO:0061574 ASAP complex(GO:0061574)
0.1 1.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 7.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.0 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 3.1 GO:0000242 pericentriolar material(GO:0000242)
0.1 2.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.9 GO:0071439 clathrin complex(GO:0071439)
0.1 1.3 GO:0005915 zonula adherens(GO:0005915)
0.1 1.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 6.6 GO:0005776 autophagosome(GO:0005776)
0.1 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 4.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 4.3 GO:0005871 kinesin complex(GO:0005871)
0.0 6.5 GO:0000776 kinetochore(GO:0000776)
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.8 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.9 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 3.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 8.8 GO:0030027 lamellipodium(GO:0030027)
0.0 1.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 7.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 3.7 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.6 GO:0016528 sarcoplasm(GO:0016528)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 4.7 GO:0016607 nuclear speck(GO:0016607)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 1.6 GO:0045111 intermediate filament cytoskeleton(GO:0045111)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 25.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
3.1 12.5 GO:0070052 collagen V binding(GO:0070052)
1.5 10.5 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.0 3.0 GO:0002055 adenine binding(GO:0002055) adenine phosphoribosyltransferase activity(GO:0003999)
0.9 3.7 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.9 2.7 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.9 3.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.9 7.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.8 7.8 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.7 6.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.6 2.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.5 1.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.5 1.9 GO:0036033 mediator complex binding(GO:0036033)
0.5 3.2 GO:0050733 RS domain binding(GO:0050733)
0.4 1.3 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.3 1.7 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.3 1.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 4.2 GO:0008097 5S rRNA binding(GO:0008097)
0.3 3.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.3 3.7 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.3 3.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 9.4 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.2 8.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 1.7 GO:0004111 creatine kinase activity(GO:0004111)
0.2 2.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 2.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 1.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.2 3.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.2 1.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 1.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 2.0 GO:0045545 syndecan binding(GO:0045545)
0.2 3.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 6.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 0.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 1.6 GO:0070538 oleic acid binding(GO:0070538)
0.1 1.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 2.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 2.2 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 2.9 GO:0008143 poly(A) binding(GO:0008143)
0.1 7.9 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.8 GO:0015616 DNA translocase activity(GO:0015616)
0.1 4.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 1.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 2.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.1 0.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 6.9 GO:0019843 rRNA binding(GO:0019843)
0.1 2.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 7.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 2.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 4.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.4 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 1.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 4.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 3.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 2.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 14.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.3 10.8 PID ATM PATHWAY ATM pathway
0.3 14.3 PID AURORA B PATHWAY Aurora B signaling
0.2 11.1 PID ATR PATHWAY ATR signaling pathway
0.2 14.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 20.0 PID E2F PATHWAY E2F transcription factor network
0.1 1.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 7.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 4.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 7.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 5.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 3.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 2.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 3.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.9 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 29.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.9 17.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.6 8.3 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.4 6.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.4 5.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3 6.8 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.3 8.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 2.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 2.9 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 3.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 1.8 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 5.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 2.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 3.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 1.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 8.5 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 13.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 3.5 REACTOME KINESINS Genes involved in Kinesins
0.1 1.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 6.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 0.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 16.5 REACTOME TRANSLATION Genes involved in Translation
0.1 1.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 3.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 2.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 3.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 3.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 3.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production