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GSE58827: Dynamics of the Mouse Liver

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Results for Egr3

Z-value: 0.72

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Transcription factors associated with Egr3

Gene Symbol Gene ID Gene Info
Egr3
ENSMUSG00000033730.5 early growth response 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Egr3mm39_v1_chr14_+_70314652_70314671-0.163.5e-01Click!

Activity profile of Egr3 motif

Sorted Z-values of Egr3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_94063823 5.19 ENSMUST00000044602.8
Ces1g
carboxylesterase 1G
chr14_+_66205932 4.03 ENSMUST00000022616.14
Clu
clusterin
chr12_-_84497718 3.79 ENSMUST00000085192.7
ENSMUST00000220491.2
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr1_+_133291302 3.26 ENSMUST00000135222.9
Etnk2
ethanolamine kinase 2
chr6_-_124519240 3.07 ENSMUST00000159463.8
ENSMUST00000162844.2
ENSMUST00000160505.8
ENSMUST00000162443.8
C1s1
complement component 1, s subcomponent 1
chr10_-_68114543 2.77 ENSMUST00000219238.2
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr17_+_25798059 2.58 ENSMUST00000141606.3
ENSMUST00000063344.15
ENSMUST00000116641.9
Lmf1
lipase maturation factor 1
chr11_-_98666159 2.44 ENSMUST00000064941.7
Nr1d1
nuclear receptor subfamily 1, group D, member 1
chr5_-_134776101 2.33 ENSMUST00000015138.13
Eln
elastin
chr4_-_129132963 1.95 ENSMUST00000097873.10
C77080
expressed sequence C77080
chr19_-_38113249 1.65 ENSMUST00000112335.4
Rbp4
retinol binding protein 4, plasma
chr11_-_69586626 1.56 ENSMUST00000108649.3
ENSMUST00000174159.8
ENSMUST00000181810.8
Tnfsfm13
Tnfsf12
tumor necrosis factor (ligand) superfamily, membrane-bound member 13
tumor necrosis factor (ligand) superfamily, member 12
chr7_-_30754792 1.54 ENSMUST00000206328.2
Fxyd1
FXYD domain-containing ion transport regulator 1
chr10_+_106306122 1.51 ENSMUST00000029404.17
ENSMUST00000217854.2
Ppfia2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr19_-_38113056 1.47 ENSMUST00000236283.2
Rbp4
retinol binding protein 4, plasma
chr7_+_34818709 1.40 ENSMUST00000205391.2
ENSMUST00000042985.11
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr11_+_4833186 1.38 ENSMUST00000139737.2
Nipsnap1
nipsnap homolog 1
chr6_+_91661074 1.10 ENSMUST00000205480.2
ENSMUST00000206545.2
Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr11_-_68277631 1.09 ENSMUST00000021284.4
Ntn1
netrin 1
chr8_+_119010458 1.05 ENSMUST00000117160.2
Cdh13
cadherin 13
chr10_-_59057570 0.96 ENSMUST00000220156.2
ENSMUST00000165971.3
Septin10
septin 10
chrX_-_47602395 0.93 ENSMUST00000114945.9
ENSMUST00000037349.8
Aifm1
apoptosis-inducing factor, mitochondrion-associated 1
chr2_-_121244251 0.91 ENSMUST00000038073.5
Catsper2
cation channel, sperm associated 2
chr2_+_121244256 0.88 ENSMUST00000028683.14
Pdia3
protein disulfide isomerase associated 3
chr13_+_59733163 0.87 ENSMUST00000166923.9
Naa35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr11_-_109613040 0.86 ENSMUST00000020938.8
Fam20a
FAM20A, golgi associated secretory pathway pseudokinase
chr18_-_38068456 0.85 ENSMUST00000080033.7
ENSMUST00000115631.8
ENSMUST00000115634.8
Diaph1
diaphanous related formin 1
chr10_-_127504416 0.82 ENSMUST00000129252.2
Nab2
Ngfi-A binding protein 2
chr18_-_38068430 0.82 ENSMUST00000025337.14
Diaph1
diaphanous related formin 1
chr16_-_94171853 0.80 ENSMUST00000113914.8
ENSMUST00000113905.8
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr13_-_85437201 0.79 ENSMUST00000223598.2
Rasa1
RAS p21 protein activator 1
chr5_+_65127412 0.73 ENSMUST00000031080.15
Fam114a1
family with sequence similarity 114, member A1
chr2_-_58457168 0.73 ENSMUST00000056376.12
Acvr1
activin A receptor, type 1
chr4_+_57637817 0.71 ENSMUST00000150412.4
Pakap
paralemmin A kinase anchor protein
chr13_-_85437118 0.69 ENSMUST00000109552.3
Rasa1
RAS p21 protein activator 1
chr2_-_143853122 0.69 ENSMUST00000016072.12
ENSMUST00000037875.6
Rrbp1
ribosome binding protein 1
chr16_-_45664664 0.67 ENSMUST00000036355.13
Phldb2
pleckstrin homology like domain, family B, member 2
chr16_-_45664591 0.67 ENSMUST00000076333.12
Phldb2
pleckstrin homology like domain, family B, member 2
chr7_+_43361930 0.63 ENSMUST00000066834.8
Klk13
kallikrein related-peptidase 13
chr18_-_84104507 0.61 ENSMUST00000060303.10
Tshz1
teashirt zinc finger family member 1
chr5_+_138278502 0.60 ENSMUST00000160729.8
Stag3
stromal antigen 3
chr18_-_84104574 0.59 ENSMUST00000175783.3
Tshz1
teashirt zinc finger family member 1
chr4_+_40948407 0.57 ENSMUST00000030128.6
Chmp5
charged multivesicular body protein 5
chr9_-_50639367 0.56 ENSMUST00000117646.8
Dixdc1
DIX domain containing 1
chr7_+_48608800 0.56 ENSMUST00000183659.8
Nav2
neuron navigator 2
chr13_+_59733073 0.55 ENSMUST00000168367.8
ENSMUST00000022038.15
Naa35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr10_+_80134917 0.52 ENSMUST00000154212.8
Apc2
APC regulator of WNT signaling pathway 2
chr10_-_17898838 0.51 ENSMUST00000220433.2
Abracl
ABRA C-terminal like
chr7_-_45159739 0.51 ENSMUST00000211682.2
ENSMUST00000033096.16
ENSMUST00000209436.2
ENSMUST00000211343.2
Nucb1
nucleobindin 1
chrX_+_142447361 0.51 ENSMUST00000126592.8
ENSMUST00000156449.8
ENSMUST00000155215.8
ENSMUST00000112865.8
Pak3
p21 (RAC1) activated kinase 3
chrX_+_35459621 0.49 ENSMUST00000115256.2
Zcchc12
zinc finger, CCHC domain containing 12
chr17_-_46638874 0.45 ENSMUST00000047970.14
Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chrX_+_142447286 0.44 ENSMUST00000112868.8
Pak3
p21 (RAC1) activated kinase 3
chr5_-_21850579 0.44 ENSMUST00000051358.11
Fbxl13
F-box and leucine-rich repeat protein 13
chr11_-_68277799 0.44 ENSMUST00000135141.2
Ntn1
netrin 1
chr10_+_40759815 0.43 ENSMUST00000105509.2
Wasf1
WASP family, member 1
chr5_-_138278223 0.42 ENSMUST00000014089.9
ENSMUST00000161827.8
Gpc2
glypican 2 (cerebroglycan)
chr5_-_62923463 0.40 ENSMUST00000076623.8
ENSMUST00000159470.3
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_158190090 0.39 ENSMUST00000194369.6
ENSMUST00000195311.6
Astn1
astrotactin 1
chr16_-_94171556 0.39 ENSMUST00000113906.9
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr10_+_40759468 0.37 ENSMUST00000019975.14
Wasf1
WASP family, member 1
chr7_+_144450260 0.36 ENSMUST00000033389.7
ENSMUST00000207229.2
Fgf15
fibroblast growth factor 15
chr2_+_27055245 0.36 ENSMUST00000000910.7
Dbh
dopamine beta hydroxylase
chr17_-_46638915 0.35 ENSMUST00000167360.8
Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr3_+_93301003 0.34 ENSMUST00000045912.3
Rptn
repetin
chr11_-_99313078 0.33 ENSMUST00000017741.4
Krt12
keratin 12
chr10_+_3784877 0.32 ENSMUST00000239159.2
Plekhg1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr15_-_98676007 0.32 ENSMUST00000226655.2
ENSMUST00000228546.2
ENSMUST00000023732.12
ENSMUST00000226610.2
Wnt10b
wingless-type MMTV integration site family, member 10B
chr10_+_83558729 0.32 ENSMUST00000150459.3
1500009L16Rik
RIKEN cDNA 1500009L16 gene
chr3_+_106943472 0.32 ENSMUST00000052718.5
Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr16_+_21023505 0.31 ENSMUST00000006112.7
Ephb3
Eph receptor B3
chr12_+_49429790 0.31 ENSMUST00000021333.5
Foxg1
forkhead box G1
chr16_-_94171533 0.30 ENSMUST00000113910.8
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr9_-_54956032 0.29 ENSMUST00000034854.8
Chrnb4
cholinergic receptor, nicotinic, beta polypeptide 4
chr11_-_89587671 0.29 ENSMUST00000128717.9
Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr19_+_6276408 0.29 ENSMUST00000025698.14
ENSMUST00000113526.2
Gpha2
glycoprotein hormone alpha 2
chr19_+_59447950 0.29 ENSMUST00000174353.2
Emx2
empty spiracles homeobox 2
chr7_-_45159790 0.29 ENSMUST00000211765.2
Nucb1
nucleobindin 1
chr10_-_17898938 0.27 ENSMUST00000220110.2
Abracl
ABRA C-terminal like
chr2_-_69416365 0.27 ENSMUST00000100051.9
ENSMUST00000092551.5
ENSMUST00000080953.12
Lrp2
low density lipoprotein receptor-related protein 2
chr1_+_120268299 0.26 ENSMUST00000037286.12
C1ql2
complement component 1, q subcomponent-like 2
chr4_-_20778530 0.25 ENSMUST00000119374.8
Nkain3
Na+/K+ transporting ATPase interacting 3
chr9_-_58111589 0.25 ENSMUST00000217578.2
ENSMUST00000114144.9
ENSMUST00000214649.2
Islr
Islr2
immunoglobulin superfamily containing leucine-rich repeat
immunoglobulin superfamily containing leucine-rich repeat 2
chr14_-_21790463 0.24 ENSMUST00000120984.9
Dusp13
dual specificity phosphatase 13
chrX_+_159945990 0.24 ENSMUST00000077375.5
Scml2
Scm polycomb group protein like 2
chr1_-_164135008 0.24 ENSMUST00000027866.11
ENSMUST00000120447.8
ENSMUST00000086032.4
Blzf1
basic leucine zipper nuclear factor 1
chr17_-_80022480 0.23 ENSMUST00000234361.2
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
chr17_-_80022463 0.23 ENSMUST00000024894.2
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
chr11_+_71641806 0.22 ENSMUST00000108511.8
Wscd1
WSC domain containing 1
chr11_+_71641505 0.21 ENSMUST00000021168.14
Wscd1
WSC domain containing 1
chrX_+_159945740 0.21 ENSMUST00000074802.12
ENSMUST00000019101.11
ENSMUST00000112345.8
Scml2
Scm polycomb group protein like 2
chr8_-_49008881 0.20 ENSMUST00000110345.8
Tenm3
teneurin transmembrane protein 3
chr6_-_83549399 0.20 ENSMUST00000206592.2
ENSMUST00000206400.2
Stambp
STAM binding protein
chr9_+_21077010 0.19 ENSMUST00000039413.15
Pde4a
phosphodiesterase 4A, cAMP specific
chr7_+_18810167 0.19 ENSMUST00000108479.2
Dmwd
dystrophia myotonica-containing WD repeat motif
chr7_+_3648264 0.19 ENSMUST00000206287.2
ENSMUST00000038913.16
Cnot3
CCR4-NOT transcription complex, subunit 3
chr14_+_55747902 0.19 ENSMUST00000165262.8
ENSMUST00000074225.11
Cpne6
copine VI
chr15_-_78428865 0.18 ENSMUST00000053239.4
Sstr3
somatostatin receptor 3
chr7_+_80510658 0.17 ENSMUST00000132163.8
ENSMUST00000205361.2
ENSMUST00000147125.2
Zscan2
zinc finger and SCAN domain containing 2
chr19_-_38212544 0.17 ENSMUST00000067167.6
Fra10ac1
FRA10AC1 homolog (human)
chr12_+_49429574 0.16 ENSMUST00000179669.3
Foxg1
forkhead box G1
chr10_-_40759307 0.15 ENSMUST00000044166.9
Cdc40
cell division cycle 40
chr11_-_107805830 0.15 ENSMUST00000039071.3
Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr11_-_103158190 0.14 ENSMUST00000021324.3
Map3k14
mitogen-activated protein kinase kinase kinase 14
chr10_-_17898977 0.14 ENSMUST00000020002.9
Abracl
ABRA C-terminal like
chr7_-_118783820 0.13 ENSMUST00000084650.6
Gpr139
G protein-coupled receptor 139
chr17_+_87590308 0.12 ENSMUST00000041110.12
ENSMUST00000125875.8
Ttc7
tetratricopeptide repeat domain 7
chr1_-_161615927 0.11 ENSMUST00000193648.2
Fasl
Fas ligand (TNF superfamily, member 6)
chr1_-_9369463 0.11 ENSMUST00000140295.8
Sntg1
syntrophin, gamma 1
chr16_-_88087087 0.11 ENSMUST00000211444.2
ENSMUST00000023652.16
ENSMUST00000072256.13
Grik1
glutamate receptor, ionotropic, kainate 1
chr8_+_63404395 0.08 ENSMUST00000119068.8
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr3_-_126955976 0.08 ENSMUST00000182994.8
Ank2
ankyrin 2, brain
chr9_+_119723931 0.08 ENSMUST00000036561.8
ENSMUST00000217472.2
ENSMUST00000215307.2
Wdr48
WD repeat domain 48
chr15_+_99122742 0.06 ENSMUST00000041415.5
Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr3_+_105359641 0.06 ENSMUST00000098761.10
Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
chr1_-_161616031 0.06 ENSMUST00000000834.4
Fasl
Fas ligand (TNF superfamily, member 6)
chr4_+_32238950 0.05 ENSMUST00000037416.13
Bach2
BTB and CNC homology, basic leucine zipper transcription factor 2
chr9_+_55056648 0.04 ENSMUST00000121677.8
Ube2q2
ubiquitin-conjugating enzyme E2Q family member 2
chr5_+_138278777 0.04 ENSMUST00000048028.15
ENSMUST00000162245.8
ENSMUST00000161691.2
Stag3
stromal antigen 3
chr4_+_99812912 0.04 ENSMUST00000102783.5
Pgm1
phosphoglucomutase 1
chr12_+_86999366 0.03 ENSMUST00000191463.2
Cipc
CLOCK interacting protein, circadian
chr8_+_63404228 0.03 ENSMUST00000118003.8
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr6_-_88851579 0.02 ENSMUST00000061262.11
ENSMUST00000140455.8
ENSMUST00000145780.2
Podxl2
podocalyxin-like 2
chr16_+_94171477 0.01 ENSMUST00000117648.9
ENSMUST00000147352.8
ENSMUST00000150346.8
ENSMUST00000155692.8
ENSMUST00000153988.9
ENSMUST00000139513.9
ENSMUST00000141856.8
ENSMUST00000152117.8
ENSMUST00000150097.8
ENSMUST00000122895.8
ENSMUST00000151770.8
ENSMUST00000231569.2
ENSMUST00000147046.8
ENSMUST00000149885.8
ENSMUST00000127667.8
ENSMUST00000119131.3
ENSMUST00000145883.2
Ttc3
tetratricopeptide repeat domain 3
chr9_-_79869299 0.00 ENSMUST00000172973.2
Filip1
filamin A interacting protein 1
chr3_+_97808506 0.00 ENSMUST00000029476.9
ENSMUST00000130620.2
ENSMUST00000122288.2
Sec22b
SEC22 homolog B, vesicle trafficking protein

Network of associatons between targets according to the STRING database.

First level regulatory network of Egr3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0090320 chylomicron assembly(GO:0034378) regulation of chylomicron remnant clearance(GO:0090320)
0.9 3.8 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.7 4.0 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.6 3.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.5 2.4 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.4 2.6 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.4 1.1 GO:0001762 beta-alanine transport(GO:0001762) taurine transport(GO:0015734)
0.3 3.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3 0.9 GO:1903334 positive regulation of protein folding(GO:1903334)
0.2 3.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 2.8 GO:0060613 fat pad development(GO:0060613)
0.2 0.6 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.2 1.2 GO:0060023 soft palate development(GO:0060023)
0.2 0.8 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.2 0.5 GO:0021852 pyramidal neuron migration(GO:0021852)
0.2 0.5 GO:0002930 trabecular meshwork development(GO:0002930) endothelial cell-cell adhesion(GO:0071603)
0.2 1.1 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 0.7 GO:0003274 endocardial cushion fusion(GO:0003274) positive regulation of determination of dorsal identity(GO:2000017)
0.1 1.5 GO:1903278 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.1 1.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 1.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.6 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.1 1.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.4 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.1 1.4 GO:0000050 urea cycle(GO:0000050)
0.1 0.6 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.8 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.3 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 1.5 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 0.9 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.1 0.3 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.4 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1 0.9 GO:0070166 enamel mineralization(GO:0070166)
0.1 1.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 1.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.9 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.0 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 1.6 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0 0.3 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.3 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.3 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.5 2.3 GO:0071953 elastic fiber(GO:0071953)
0.4 1.4 GO:0031417 NatC complex(GO:0031417)
0.3 4.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.8 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.6 GO:0000802 transverse filament(GO:0000802)
0.1 0.4 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.1 0.9 GO:0042825 TAP complex(GO:0042825)
0.1 1.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.1 0.9 GO:0036128 CatSper complex(GO:0036128)
0.1 1.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 1.7 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 3.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0034632 retinol transporter activity(GO:0034632)
0.8 3.3 GO:0004103 choline kinase activity(GO:0004103)
0.4 1.1 GO:0005368 beta-alanine transmembrane transporter activity(GO:0001761) taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
0.3 0.9 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.2 0.9 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 1.1 GO:0055100 adiponectin binding(GO:0055100)
0.2 4.0 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.4 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 1.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.7 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 2.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.3 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 1.4 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.1 1.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 3.8 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 1.5 GO:0043422 platelet-derived growth factor receptor binding(GO:0005161) protein kinase B binding(GO:0043422)
0.0 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.7 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 5.2 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 1.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 3.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.5 GO:0032183 SUMO binding(GO:0032183)
0.0 0.5 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 4.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 5.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 2.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 3.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.5 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 2.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 2.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis